LOCUS       NZ_BMVR01000032        22703 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence32, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000032
VERSION     NZ_BMVR01000032.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 22703)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 22703
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000032.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22703
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..22703
                     /SMILES="C([*])C(-O)C=CCCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22703
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2986:18206](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2987..18206)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            <1..926
                     /locus_tag="IE274_RS38475"
     source          1..22703
                     /culture_collection="JCM:4753"
                     /db_xref="taxon:68200"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces flavofungini"
                     /strain="JCM 4753"
                     /submitter_seqid="sequence32"
                     /type_material="type strain of Streptomyces flavofungini"
     aSDomain        <7..164
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38475_PCP.1"
                     /evalue="1.30E-20"
                     /label="IE274_RS38475_PCP.1"
                     /locus_tag="IE274_RS38475"
                     /protein_end="53"
                     /protein_start="0"
                     /score="65.3"
                     /tool="antismash"
                     /translation="RVGVDDNFFTVGGHSLLATRLVSRIRTVLGVEIPMRVVFQYATVA
                     EMADCLTS"
     aSModule        <7..911
                     /domains="nrpspksdomains_IE274_RS38475_PCP.1"
                     /domains="nrpspksdomains_IE274_RS38475_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="IE274_RS38475"
                     /tool="antismash"
                     /type="unknown"
     CDS             <5..926
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PCP (0-53). E-value: 1.3e-20. Score:
                     65.3. Matches aSDomain: nrpspksdomains_IE274_RS38475_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (77-302). E-value: 6.8e-34.
                     Score: 110.2. Matches aSDomain:
                     nrpspksdomains_IE274_RS38475_Thioesterase.1"
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.5"
                     /locus_tag="IE274_RS38475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase domain-containing protein"
                     /protein_id="WP_229910109.1"
                     /sec_met_domain="PP-binding (E-value: 8.3e-16, bitscore:
                     47.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 9.6e-27, bitscore:
                     83.7, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.2e-08, bitscore: 21.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RVGVDDNFFTVGGHSLLATRLVSRIRTVLGVEIPMRVVFQYATVA
                     EMADCLTSGKESFSLTDPFGVVLPMKTDGDAGPLWFVHPGVGLSWVYLGFATQLGDRPV
                     YGIQARGFDGSELPGSIDEMVADYLEQILAVQPQGPFRLVGLSIGGTLAHALAGELQAR
                     GHEVALLGLLDCVPAEWFARNHTSLETAEVADVLAGYIPHTAPKGGDPADGAEDGERNS
                     LVRNASAIAVRHTDMMRAYTQPTYRGDAVFFNATLNPDETYAPQWAAYIEGTVAEHDVH
                     ATHLGMCRPRPAAEICRVLSRHLDSE"
     misc_feature    16..31
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.08"
                     /tool="antismash"
     aSDomain        237..911
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38475_Thioesterase.1"
                     /evalue="6.80E-34"
                     /label="IE274_RS38475_Thioesterase.1"
                     /locus_tag="IE274_RS38475"
                     /protein_end="302"
                     /protein_start="77"
                     /score="110.2"
                     /tool="antismash"
                     /translation="PLWFVHPGVGLSWVYLGFATQLGDRPVYGIQARGFDGSELPGSID
                     EMVADYLEQILAVQPQGPFRLVGLSIGGTLAHALAGELQARGHEVALLGLLDCVPAEWF
                     ARNHTSLETAEVADVLAGYIPHTAPKGGDPADGAEDGERNSLVRNASAIAVRHTDMMRA
                     YTQPTYRGDAVFFNATLNPDETYAPQWAAYIEGTVAEHDVHATHLGMCRPRPAAEICRV
                     LSR"
     CDS_motif       411..485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38475_0001"
                     /evalue="7.20E-10"
                     /label="NRPS-te1"
                     /locus_tag="IE274_RS38475"
                     /protein_end="160"
                     /protein_start="135"
                     /score="31.3"
                     /tool="antismash"
                     /translation="QPQGPFRLVGLSIGGTLAHALAGEL"
     gene            complement(993..2186)
                     /locus_tag="IE274_RS38480"
                     /old_locus_tag="GCM10010349_78600"
     CDS             complement(993..2186)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998796.1"
                     /locus_tag="IE274_RS38480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78600"
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="WP_190120603.1"
                     /transl_table=11
                     /translation="MSEQTGAPGAARAELVRQIYLAGISGHKPELSTDLTSLEEAARAV
                     LEPHAYAYIAGNAGTGTTGRANREAFERWRLLPRMWTGVSERDLSVTLFGQRLDAPVLL
                     APVAAQTVAHPEGELASVRAAADVGLPFVLSSVSSHSMEDVAKAAGSEPRWYQLYWPND
                     PAVAESLVRRVESAGYAAIVVTVDNPAFGYRPCDMDTAYIPFVHGHGIANFTSDPAFRA
                     GLPEDGGPLAAAGHWAKISSNPALTWDDLPRLRSWTTLPILIKGIQHPDDARKALASGA
                     NGVVVSNHGGRQLDGGVAALDVLPAVRAALGPDVPVLMDSGVRTGTDVVKALALGADAI
                     LLGRPYLYGLALAGQAGVEHVLRCLLADLDLALALTGSRSVADITRDLVVPSGPLAP"
     gene            complement(2183..2968)
                     /locus_tag="IE274_RS38485"
                     /old_locus_tag="GCM10010349_78610"
     CDS             complement(2183..2968)
                     /NRPS_PKS="Domain: Thioesterase (18-229). E-value: 9.2e-48.
                     Score: 155.6. Matches aSDomain:
                     nrpspksdomains_IE274_RS38485_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.5"
                     /locus_tag="IE274_RS38485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78610"
                     /product="thioesterase II family protein"
                     /protein_id="WP_190120604.1"
                     /sec_met_domain="Thioesterase (E-value: 5e-48, bitscore:
                     153.3, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.5e-15, bitscore:
                     45.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKKWIRTFHAKPDARARLVCFPHAGGPALAFTALSAALPADVE
                     LLAVQYPGRQDRRAEPFAEDVTTLAAGVVDALAAFDDRPLFLLGHSFGALVAFESARLL
                     EERAGLARLFASAAWPPSADWRAHAGGVHSDEELLGHVRWLGGVPDALLDDPETVAEMT
                     RLLRGDQEVLGRYQAADGAAVTAPLTVLLARDDPKNTAGQLADWERHTTGEYGLELLPG
                     GHFALTEPGPTVVPLLTRVIREDLRRAAATGTTGQVVGA"
     aSDomain        complement(2282..2914)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38485_Thioesterase.1"
                     /evalue="9.20E-48"
                     /label="IE274_RS38485_Thioesterase.1"
                     /locus_tag="IE274_RS38485"
                     /protein_end="229"
                     /protein_start="18"
                     /score="155.6"
                     /tool="antismash"
                     /translation="RLVCFPHAGGPALAFTALSAALPADVELLAVQYPGRQDRRAEPFA
                     EDVTTLAAGVVDALAAFDDRPLFLLGHSFGALVAFESARLLEERAGLARLFASAAWPPS
                     ADWRAHAGGVHSDEELLGHVRWLGGVPDALLDDPETVAEMTRLLRGDQEVLGRYQAADG
                     AAVTAPLTVLLARDDPKNTAGQLADWERHTTGEYGLELLPGGHFALTE"
     CDS_motif       complement(2657..2725)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38485_0001"
                     /evalue="1.20E-08"
                     /label="NRPS-te1"
                     /locus_tag="IE274_RS38485"
                     /protein_end="104"
                     /protein_start="81"
                     /score="27.3"
                     /tool="antismash"
                     /translation="DRPLFLLGHSFGALVAFESARLL"
     misc_feature    complement(2958..2974)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            complement(2987..9496)
                     /locus_tag="IE274_RS38490"
                     /old_locus_tag="GCM10010349_78620"
     CDS             complement(2987..9496)
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (38-463). E-value:
                     3.4e-183. Score: 601.3. Matches aSDomain:
                     nrpspksdomains_IE274_RS38490_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (571-871). E-value: 1.1e-104.
                     Score: 341.9. Matches aSDomain:
                     nrpspksdomains_IE274_RS38490_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (939-1106). E-value: 2.1e-52.
                     Score: 169.8. Matches aSDomain:
                     nrpspksdomains_IE274_RS38490_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1432-1741). E-value: 3.3e-107.
                     Score: 350.2. Matches aSDomain:
                     nrpspksdomains_IE274_RS38490_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1755-1932). E-value: 3.7e-54.
                     Score: 175.4. Matches aSDomain:
                     nrpspksdomains_IE274_RS38490_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (2030-2102). E-value: 6.4e-26.
                     Score: 82.5. Matches aSDomain:
                     nrpspksdomains_IE274_RS38490_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645776.1"
                     /locus_tag="IE274_RS38490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78620"
                     /product="type I polyketide synthase"
                     /protein_id="WP_190120605.1"
                     /sec_met_domain="mod_KS (E-value: 8.8e-228, bitscore:
                     745.2, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.6e-96, bitscore:
                     311.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-105, bitscore:
                     341.9, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 9.1e-17, bitscore:
                     50.4, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.1e-55, bitscore:
                     177.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9e-14, bitscore:
                     41.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASTSPQQVVAALRAALKENERLKAANARAEERAGEPMAIVGMGC
                     RFPGGVSSPQDLWQLVADEVDAVGAFPTDRGWDLSHLFDPDPDHAGTSYVEQGGFLYDA
                     ARFDPEFFGISPREAHAIDPQQRLLLETAWEAFEHAGIDPTTLRGSRTGVFVGTMYDDY
                     AARLSPAPEEYEAYLTIGSTGSVASGRISYTFGLQGPAITVDTACSSSLVALHLAVDSL
                     RRGECSLALAGGATLMATPNSFVEFSRQRGLSKDGRCKSFAAAADGTAWAEGAGLLLVE
                     RLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGPAQEALIKQALAGAGLSGADVDLL
                     EAHGTGTPLGDPLEANALLATYGAARTSANPLYLGSLKSNIGHAQAAAGVGGLIKLTMA
                     LRHGVLPKTLHVDEPSPNVDWSTGTLELLTEAKAWPRVDRPRRAAVSSFGIGGTNAHVI
                     LEQAPEPVERPAEERAGKSLPAVPHVLSAATEAALRAQADRLHQHLTAEPSVTADGLAP
                     LGLSLATTRAHLAHRAVLTAADRASLLTRLRALADDAADPEVVRGKAAEGRTAFLFAGQ
                     GSQRPGMGKDLYEAFPAYAAAFDAVCAVVDPQLAEPLAEVVLAAEGTPTADLLNRTEYT
                     QPALFAVEVALFRLFESWGIRPDAVLGHSVGAFAAVHAAGVLSLADAAQLAVARGRIMQ
                     RLPAGGAMVALRTSEEEAVGLLAGYAGKVSLAAVNGPAATVLSGDKEALAAAVRPFEEA
                     GGKATRLNVSHAFHSPLMEPALAEFRALAASLEFRSPELTVVSDLTGRAVEPDELADPD
                     YWARHLLSTVRFQDGVRGLAADGCVRFLELGPSGDLTAMAADCLAGQRTAHELIPSLRR
                     RHPETGTLLTALGRTHTSGGDVDWAAVFAGHGAHRVELPTYAFQRRPYWLDKRVVPGDV
                     RSAGLVALDHPTLTAVAELPEPDGLLLTGRLSLATHAWLADHKVGDQVLVPGTALLDLA
                     ARSARAAGCDVVEELLLEAPLIVAEDTEVQLRVFLSAPDATGSRAVTVHSRREDDTDLG
                     GWLRNASGSVAGATAEAAPADLTVWPPQGAEELAVAPDDLYADLAAKGLSYGPVFRGVK
                     AVYQRGDEVFAEVALPDGKQPGAGGYGLHPALLDAALHPSAAGGLTDSPGGRTLLPYAW
                     SNARTLGTADAALRVRLAPAGRNAISVDVADAAGKPVAAIGSLALRPAATASASDRDGL
                     YVPSWEALSELPAAGDTELWAVLGDFADEAPHGVVTRRFADQASLSEALDEGEEAPEVI
                     LLPVAAGRADGIPDPAAVRDSLRHVLTTAQLVLADDRLSATRLVAVTRGAVAVDAEQPT
                     GRLGPRSVWGLLRSAIAEHPGRFALLDEDGTAGSRAALAGAVAAAEPQLALRGGTAYRP
                     ALSTTAPGSTLRPPPNEPNWYLDYVAKSSFANLSFEPWPEIAEPLKEGQIRLRLRAAGL
                     NFREALLALGVIHASVDADASDNGGGGEGAGVVVEVGPGVTDLKPGDRVMGLINGIGPN
                     TVTDHRLVCRIPDGWSFRQAAAVPVTYLTAYYGLVDLARLGAGESVLVHAGAGGVGTAA
                     VQIAEHLGATVYATASRGKWDALRAAGVAEERIASSRTLDFEQSFLGVSGGQGVDVVLN
                     SLAGEFADASLRLLPRGGRFLEMGKTDRRDPAEVGARHPGVDYRAYDVREPGPDRIQGM
                     LQELLELFLQGALQAPPISVWDIRRAPDAFRYLSEARHIGKVVLALSDPDEPYDTTRAA
                     LVTGGLGWLGRLVARHLVAEHGVRSVVLMGRGAPTQDARRDIDELRARGVDVRVVACDA
                     ADRDALAAALAGLAADGVRVGSVLHAAGVLDDGILADLTPESLDRSLRPKVDAALHLHE
                     LTEHLGLDAFVLFSSLAGTMGSPAQGGYAAGNSFLDGLVEYRRSIGRPGVSIAWGLWEG
                     VGGMGAGLTDTDLTRLSRIGVAPLTPERGLELLDAAVRRDAPVAVAAAWHLAGLRDRLA
                     TGGTVPALLENLVPAPARGAEAATADAPAASAGTGDRLLDTVLQEVAAVLGHASGAVVD
                     PHGAFDQIGFDSLTAVELRNRLGAATGVKLPATFIYDWPTTTELVAHLKAEQGRVTGAA
                     GADGAAARPADPDRGPQALLDGITQLESVFAEVTGAQLGDAVRDTVTDRLTALLTKLGS
                     "
     aSDomain        complement(3191..3406)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38490_ACP.1"
                     /evalue="6.40E-26"
                     /label="IE274_RS38490_ACP.1"
                     /locus_tag="IE274_RS38490"
                     /protein_end="2102"
                     /protein_start="2030"
                     /score="82.5"
                     /tool="antismash"
                     /translation="LDTVLQEVAAVLGHASGAVVDPHGAFDQIGFDSLTAVELRNRLGA
                     ATGVKLPATFIYDWPTTTELVAHLKAE"
     aSModule        complement(3191..9382)
                     /complete
                     /domains="nrpspksdomains_IE274_RS38490_PKS_KS.1"
                     /domains="nrpspksdomains_IE274_RS38490_PKS_AT.1"
                     /domains="nrpspksdomains_IE274_RS38490_PKS_DH.1"
                     /domains="nrpspksdomains_IE274_RS38490_PKS_ER.1"
                     /domains="nrpspksdomains_IE274_RS38490_PKS_KR.1"
                     /domains="nrpspksdomains_IE274_RS38490_ACP.1"
                     /locus_tags="IE274_RS38490"
                     /monomer_pairings="mal -> redmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(3548..3574)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0016"
                     /evalue="4.50E+01"
                     /label="PKSI-ER_m4"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1983"
                     /protein_start="1974"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="PVAVAAAWH"
     aSDomain        complement(3701..4231)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38490_PKS_KR.1"
                     /evalue="3.70E-54"
                     /label="IE274_RS38490_PKS_KR.1"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1932"
                     /protein_start="1755"
                     /score="175.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="ALVTGGLGWLGRLVARHLVAEHGVRSVVLMGRGAPTQDARRDIDE
                     LRARGVDVRVVACDAADRDALAAALAGLAADGVRVGSVLHAAGVLDDGILADLTPESLD
                     RSLRPKVDAALHLHELTEHLGLDAFVLFSSLAGTMGSPAQGGYAAGNSFLDGLVEYRRS
                     IGRPGVSIAWGLWE"
     CDS_motif       complement(3746..3856)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0015"
                     /evalue="5.80E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1917"
                     /protein_start="1880"
                     /score="60.7"
                     /tool="antismash"
                     /translation="LDAFVLFSSLAGTMGSPAQGGYAAGNSFLDGLVEYRR"
     CDS_motif       complement(4136..4228)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0014"
                     /evalue="1.50E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1787"
                     /protein_start="1756"
                     /score="20.8"
                     /tool="antismash"
                     /translation="LVTGGLGWLGRLVARHLVAEHGVRSVVLMGR"
     CDS_motif       complement(4274..4321)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0013"
                     /evalue="3.20E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1741"
                     /protein_start="1725"
                     /score="20.0"
                     /tool="antismash"
                     /translation="AFRYLSEARHIGKVVL"
     aSDomain        complement(4274..5200)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38490_PKS_ER.1"
                     /evalue="3.30E-107"
                     /label="IE274_RS38490_PKS_ER.1"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1741"
                     /protein_start="1432"
                     /score="350.2"
                     /tool="antismash"
                     /translation="ANLSFEPWPEIAEPLKEGQIRLRLRAAGLNFREALLALGVIHASV
                     DADASDNGGGGEGAGVVVEVGPGVTDLKPGDRVMGLINGIGPNTVTDHRLVCRIPDGWS
                     FRQAAAVPVTYLTAYYGLVDLARLGAGESVLVHAGAGGVGTAAVQIAEHLGATVYATAS
                     RGKWDALRAAGVAEERIASSRTLDFEQSFLGVSGGQGVDVVLNSLAGEFADASLRLLPR
                     GGRFLEMGKTDRRDPAEVGARHPGVDYRAYDVREPGPDRIQGMLQELLELFLQGALQAP
                     PISVWDIRRAPDAFRYLSEARHIGKVVL"
     CDS_motif       complement(4577..4612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0012"
                     /evalue="1.40E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1640"
                     /protein_start="1628"
                     /score="14.4"
                     /tool="antismash"
                     /translation="GGQGVDVVLNSL"
     CDS_motif       complement(4748..4810)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0011"
                     /evalue="1.60E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1583"
                     /protein_start="1562"
                     /score="26.8"
                     /tool="antismash"
                     /translation="GESVLVHAGAGGVGTAAVQIA"
     CDS_motif       complement(4835..4879)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0010"
                     /evalue="1.60E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1554"
                     /protein_start="1539"
                     /score="15.0"
                     /tool="antismash"
                     /translation="AAAVPVTYLTAYYGL"
     aSDomain        complement(6179..6679)
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38490_PKS_DH.1"
                     /evalue="2.10E-52"
                     /label="IE274_RS38490_PKS_DH.1"
                     /locus_tag="IE274_RS38490"
                     /protein_end="1106"
                     /protein_start="939"
                     /score="169.8"
                     /tool="antismash"
                     /translation="HPTLTAVAELPEPDGLLLTGRLSLATHAWLADHKVGDQVLVPGTA
                     LLDLAARSARAAGCDVVEELLLEAPLIVAEDTEVQLRVFLSAPDATGSRAVTVHSRRED
                     DTDLGGWLRNASGSVAGATAEAAPADLTVWPPQGAEELAVAPDDLYADLAAKGLSYGPV
                     FRGV"
     CDS_motif       complement(6530..6595)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0009"
                     /evalue="2.40E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE274_RS38490"
                     /protein_end="989"
                     /protein_start="967"
                     /score="26.5"
                     /tool="antismash"
                     /translation="WLADHKVGDQVLVPGTALLDLA"
     aSDomain        complement(6884..7783)
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: False"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38490_PKS_AT.1"
                     /evalue="1.10E-104"
                     /label="IE274_RS38490_PKS_AT.1"
                     /locus_tag="IE274_RS38490"
                     /protein_end="871"
                     /protein_start="571"
                     /score="341.9"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFAGQGSQRPGMGKDLYEAFPAYAAAFDAVCAVVDPQLAEPLAEV
                     VLAAEGTPTADLLNRTEYTQPALFAVEVALFRLFESWGIRPDAVLGHSVGAFAAVHAAG
                     VLSLADAAQLAVARGRIMQRLPAGGAMVALRTSEEEAVGLLAGYAGKVSLAAVNGPAAT
                     VLSGDKEALAAAVRPFEEAGGKATRLNVSHAFHSPLMEPALAEFRALAASLEFRSPELT
                     VVSDLTGRAVEPDELADPDYWARHLLSTVRFQDGVRGLAADGCVRFLELGPSGDLTAMA
                     ADCLAGQRTAHELIPSLRR"
     CDS_motif       complement(7025..7060)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0008"
                     /evalue="5.40E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE274_RS38490"
                     /protein_end="824"
                     /protein_start="812"
                     /score="13.4"
                     /tool="antismash"
                     /translation="YWARHLLSTVRF"
     CDS_motif       complement(7283..7321)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0007"
                     /evalue="1.60E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE274_RS38490"
                     /protein_end="738"
                     /protein_start="725"
                     /score="11.8"
                     /tool="antismash"
                     /translation="AAVNGPAATVLSG"
     CDS_motif       complement(7415..7537)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0006"
                     /evalue="8.10E-19"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE274_RS38490"
                     /protein_end="694"
                     /protein_start="653"
                     /score="59.8"
                     /tool="antismash"
                     /translation="GIRPDAVLGHSVGAFAAVHAAGVLSLADAAQLAVARGRIMQ"
     CDS_motif       complement(7541..7609)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0005"
                     /evalue="8.00E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE274_RS38490"
                     /protein_end="652"
                     /protein_start="629"
                     /score="15.7"
                     /tool="antismash"
                     /translation="NRTEYTQPALFAVEVALFRLFES"
     CDS_motif       complement(7733..7786)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0004"
                     /evalue="2.50E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE274_RS38490"
                     /protein_end="588"
                     /protein_start="570"
                     /score="16.8"
                     /tool="antismash"
                     /translation="FLFAGQGSQRPGMGKDLY"
     aSDomain        complement(8108..9382)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38490_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.40E-183"
                     /label="IE274_RS38490_PKS_KS.1"
                     /locus_tag="IE274_RS38490"
                     /protein_end="463"
                     /protein_start="38"
                     /score="601.3"
                     /tool="antismash"
                     /translation="AIVGMGCRFPGGVSSPQDLWQLVADEVDAVGAFPTDRGWDLSHLF
                     DPDPDHAGTSYVEQGGFLYDAARFDPEFFGISPREAHAIDPQQRLLLETAWEAFEHAGI
                     DPTTLRGSRTGVFVGTMYDDYAARLSPAPEEYEAYLTIGSTGSVASGRISYTFGLQGPA
                     ITVDTACSSSLVALHLAVDSLRRGECSLALAGGATLMATPNSFVEFSRQRGLSKDGRCK
                     SFAAAADGTAWAEGAGLLLVERLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGPAQ
                     EALIKQALAGAGLSGADVDLLEAHGTGTPLGDPLEANALLATYGAARTSANPLYLGSLK
                     SNIGHAQAAAGVGGLIKLTMALRHGVLPKTLHVDEPSPNVDWSTGTLELLTEAKAWPRV
                     DRPRRAAVSSFGIGGTNAHVILEQAP"
     CDS_motif       complement(8330..8374)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0003"
                     /evalue="4.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE274_RS38490"
                     /protein_end="389"
                     /protein_start="374"
                     /score="9.8"
                     /tool="antismash"
                     /translation="GSLKSNIGHAQAAAG"
     CDS_motif       complement(8435..8479)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0002"
                     /evalue="2.60E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE274_RS38490"
                     /protein_end="354"
                     /protein_start="339"
                     /score="10.4"
                     /tool="antismash"
                     /translation="LEAHGTGTPLGDPLE"
     CDS_motif       complement(8855..8902)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38490_0001"
                     /evalue="1.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE274_RS38490"
                     /protein_end="214"
                     /protein_start="198"
                     /score="20.4"
                     /tool="antismash"
                     /translation="GPAITVDTACSSSLVA"
     gene            complement(9546..18206)
                     /locus_tag="IE274_RS38495"
                     /old_locus_tag="GCM10010349_78630"
     CDS             complement(9546..18206)
                     /EC_number="2.3.1.-"
                     /EC_number="6.4.-.-"
                     /GO_component="GO:0034081 - polyketide synthase complex
                     [Evidence IEA]"
                     /GO_process="GO:0030639 - polyketide biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (16-436). E-value:
                     1.7e-164. Score: 539.7. Matches aSDomain:
                     nrpspksdomains_IE274_RS38495_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (569-865). E-value: 1.8e-96.
                     Score: 314.9. Matches aSDomain:
                     nrpspksdomains_IE274_RS38495_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (979-1051). E-value: 1.4e-27. Score:
                     87.8. Matches aSDomain: nrpspksdomains_IE274_RS38495_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1076-1502). E-value:
                     2.7e-176. Score: 578.6. Matches aSDomain:
                     nrpspksdomains_IE274_RS38495_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (1617-1911). E-value: 1.7e-104.
                     Score: 341.3. Matches aSDomain:
                     nrpspksdomains_IE274_RS38495_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_DH (1979-2144). E-value: 5.1e-48.
                     Score: 155.5. Matches aSDomain:
                     nrpspksdomains_IE274_RS38495_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (2483-2661). E-value: 1.1e-61.
                     Score: 200.0. Matches aSDomain:
                     nrpspksdomains_IE274_RS38495_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (2761-2832). E-value: 4.2e-27.
                     Score: 86.3. Matches aSDomain:
                     nrpspksdomains_IE274_RS38495_ACP.2"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (2838-2884). E-value:
                     4.7e-05. Score: 16.1. Matches aSDomain:
                     nrpspksdomains_IE274_RS38495_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020556935.1"
                     /locus_tag="IE274_RS38495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78630"
                     /product="type I polyketide synthase"
                     /protein_id="WP_190120606.1"
                     /sec_met_domain="hyb_KS (E-value: 4.6e-170, bitscore:
                     555.1, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 2.2e-222, bitscore:
                     727.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.2e-92, bitscore:
                     299.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.3e-105, bitscore:
                     341.3, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4e-63, bitscore:
                     201.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.6e-15, bitscore:
                     44.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDNTRSDAGLAGEPIAVVGMSCRFPGAPDPEAYWRLLVTGRDA
                     VTDTPAERAELGLGIEHGPAGKGAFLDGIDRFDPGFFAIPPREAAMMDPQQRLVLELGW
                     EALEQAGVVPAGLQGGDTGIFLGATTGDYADLVHRSAGDGSNVTHHSFTGLDRSLIANR
                     VSYVLGLRGPSLTVDAGQASSLVAVHMACQSLRNGESEVALAGGVELHLAPEKTALAQK
                     FGGLSPDGRCYTFDARANGYVRGEGGAVVVLKTLRRALADGDRVHAVLRGSAVNNDGGG
                     AGLTVPHEDAQRDLLRRAHERAGTAPADVGYVELHGTGTPVGDPVEAAALGAVLGAARP
                     DGEPLLVGSVKTNIGHLGAAAGMAGLLKVVLSLTHGRLPPSLHYRSPNPRIPMAELNLR
                     VQDAVGDWPGAGAQRLAGVSSFSVGGTNCHVVVSSAPEGAEGAARAEGAADADSEGAVA
                     ATADVTDGQDAAPAVSASLRGATLPWLLSGRTSAAVRAQAERLLAHLESGTESAGDIGL
                     SLATTRTAFKHRAVLLGADRDELTAELAALAEGRRSATRISGTATARERVVFVFPGQGP
                     QWTGMAGDLLDASEVFRARFDECAAALAPHIDWDLEAVLRDAPGAASLEREDVAQPALF
                     AVMVSLAALWQSFGVRPAAVVGHSNGEISAAVVAGALSLEDGARVVARWSRAMLAVVGR
                     GTMLSVPLPVAEVTPRLSAWEGRLFVSAINGPRLFTLSGDVEAIEALRAELVAEGVQAR
                     RVPIGLAPHCAWMEVLREEILGLLAPIRPRTPTLPMYSTITGALVDGPVLDGAYWMSNL
                     TSTVDFERTVRELAPETGAFVEIAPHPVLGMALRQITEDVGSDAAVVGTLRRGEDGQRR
                     FLTSLAQLNASGAEVDWRPAFPADASVVELPTYAFQRRGYWLEGVAGTTAAPAGEAAPA
                     TASAPADNGPRADLVPAATAAACRESDAARADDGPGLRGLGPEETLARVLDLVRAEAAL
                     VLGHDGGDDVDPESAFTDLGFESVTAVEMRDRLVAATGLKLPATLLFNHPTPRHLAARV
                     AGEILGTTSAPKASGRRAAVRGGAEDDPIVIVSMACRFPGGVASPEDLWQLVLDGRDAI
                     SPFPENRGWPLGALFDDDPDRAGRSYAREGGFLHDADLFDAEFFGISPREATGLDPQQR
                     LVLETVWETVERSGIDPAELRGSDTGVYVGAMKQDYGPRLDADDDTASGYLLTGSFTSL
                     VSGRAAYTFGLQGPAVTVDTACSSSLVAVHMAARALRDGECDLAFAGGVTVMSSPGMFT
                     EFSRQRGLSPDGRCKAFADSADGTGWAEGAGMLMLERLSDARRRGHEVLAVVRGSALSQ
                     DGASNGLTAPNGLSQERVILDALAGADLTVADVDVVEAHGTGTTLGDPIEAQALLATYG
                     RRAGAVEPLYLGSLKSNVGHAQAAAGVGGLIKMVLAMRHGVLPRTLHIDAPSSHVDWTS
                     GAVALLTEARPWPETGRARRAGISSFGISGTNAHVIVEQAPAVEPAPRAAGPAPVPAAP
                     WLLSGRTGGALRAGAARLRDFVAAHPERDPADIGLSLMSARTRFAHTAAVVAEDREGFL
                     RGLAALAAGESAAGVLHGPPAVPTKAVTGRAGKGGTAFLFTGQGSQRLGMGRELYEHSP
                     AFAAALDTVCAHLDPHLPHAVRDVVFAAEGSDEAALLDQTLYTQAALFAVEVALFRLME
                     LSGLRADYLIGHSVGELAAAHAAGVLGLADACALVAARGRLMQAAPDGGAMVAVEATEE
                     EVRAALPRYAGRLDVAALNGPLAAVVAGDEGAALALAAAFEEQGRRTSRLKVSHAFHSH
                     HMDGVLDEFRAVAAGLTYAAPRIPVVSNLTGALATPEELASPDYWTSHLRGAVRFQDGV
                     RVLHEAGVTAYVELGPDAVLAAMVRNCLGEERAEAAAPVAVLRTGRSESLTVAAALGHA
                     ALRGAALDTARLFPGAVRTDLPTYAFQRERYWLTAAGNAPAQHSTGHPLLGQAVELAGG
                     QGWLFTGDIDPDAHRWLADHTLLGQPLLPGAAVAELALYAGRKSGAERVGDIALERPLP
                     LSEPMGLQLMVGPADADGSRAFTLYARPRAAVKDDWKRHAAGVLEVAGPTAAPEGSAAL
                     ALWPPLDAAPVPVDGRYAELAERGYEYGPAFQGLRAMWRRGAEVYAEVELPAAAHARGF
                     QLQPAALDSALQALVGDAGTRLVVPFAWSGLTLHSPGATALRVRIRRHGEDSCSVHIAD
                     ETGTPVLDAETLVVRELPAAALASAASADGAALFALDWAEPRTPGATPVGTWAVVGHDR
                     SHLTDAVRATGVSVDAYPDLAGLRRALDDGAAVPTVVVATGPGGSAAPSGCPTSEPVTS
                     GPATTGGPTEPGGPTAGPAAATRAALALAQAFLADPRLTGSRLAVVTERAVAVTADERV
                     DLAAAPVWGLLRSAQTEHPGRFTLVDTDGRPESGPGVVRAAAGADPQLALRAGRVTTPL
                     LRRHEPRTGAAPAFDATSHVLITGGLGTLGRLLARHLVMEHGVRRLLLTGRRGMSTPGA
                     EEFVASLRAAGAEVRVAACDTADRAALAGVLGAIPAEHPLTGVVHAAGVLDDAVLGSLT
                     PERLDAVLRPKAAGAAHLDELTRGLDLTAFVLFSSFAGTLGTPGQANYAAANAYLDGLA
                     QRRRAEGRPALSVAWGLWADESALTGHLGEADLLRLRRSGIGTLSAEDGLALFDAALGD
                     GAPVLTALVLDPRALDRTTAPAVLKHLAPHRSAAVAPPRDSAAELRGKLGRAPEREHRH
                     LVLQLVRAEVAAVLGQEPGQVPAGRRFQDLGLTSLSAVELRNRLLAATGVTLPPTLVFD
                     HPTPGSLAQWLLGALTPEPAGASVTTDGAGPHGLRHAPVGGGPSTSESLLDDMDTDDLI
                     RLALGDSET"
     aSDomain        complement(9555..9692)
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_PKS_Docking_Cterm.
                     1"
                     /evalue="4.70E-05"
                     /label="IE274_RS38495_PKS_Docking_Cterm.1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="2884"
                     /protein_start="2838"
                     /score="16.1"
                     /tool="antismash"
                     /translation="GASVTTDGAGPHGLRHAPVGGGPSTSESLLDDMDTDDLIRLALGD
                     S"
     aSDomain        complement(9711..9923)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_ACP.2"
                     /evalue="4.20E-27"
                     /label="IE274_RS38495_ACP.2"
                     /locus_tag="IE274_RS38495"
                     /protein_end="2832"
                     /protein_start="2761"
                     /score="86.3"
                     /tool="antismash"
                     /translation="LQLVRAEVAAVLGQEPGQVPAGRRFQDLGLTSLSAVELRNRLLAA
                     TGVTLPPTLVFDHPTPGSLAQWLLGA"
     aSModule        complement(9711..14978)
                     /complete
                     /domains="nrpspksdomains_IE274_RS38495_PKS_KS.2"
                     /domains="nrpspksdomains_IE274_RS38495_PKS_AT.2"
                     /domains="nrpspksdomains_IE274_RS38495_PKS_DH.1"
                     /domains="nrpspksdomains_IE274_RS38495_PKS_KR.1"
                     /domains="nrpspksdomains_IE274_RS38495_ACP.2"
                     /locus_tags="IE274_RS38495"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(10224..10757)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_PKS_KR.1"
                     /evalue="1.10E-61"
                     /label="IE274_RS38495_PKS_KR.1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="2661"
                     /protein_start="2483"
                     /score="200.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="VLITGGLGTLGRLLARHLVMEHGVRRLLLTGRRGMSTPGAEEFVA
                     SLRAAGAEVRVAACDTADRAALAGVLGAIPAEHPLTGVVHAAGVLDDAVLGSLTPERLD
                     AVLRPKAAGAAHLDELTRGLDLTAFVLFSSFAGTLGTPGQANYAAANAYLDGLAQRRRA
                     EGRPALSVAWGLWAD"
     CDS_motif       complement(10272..10376)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0027"
                     /evalue="1.50E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE274_RS38495"
                     /protein_end="2645"
                     /protein_start="2610"
                     /score="62.5"
                     /tool="antismash"
                     /translation="AFVLFSSFAGTLGTPGQANYAAANAYLDGLAQRRR"
     CDS_motif       complement(10659..10754)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0026"
                     /evalue="2.40E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="2516"
                     /protein_start="2484"
                     /score="26.6"
                     /tool="antismash"
                     /translation="LITGGLGTLGRLLARHLVMEHGVRRLLLTGRR"
     CDS_motif       complement(11775..11807)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0025"
                     /evalue="1.10E-02"
                     /label="PKSI-DH_m3"
                     /locus_tag="IE274_RS38495"
                     /protein_end="2144"
                     /protein_start="2133"
                     /score="8.8"
                     /tool="antismash"
                     /translation="GYEYGPAFQGL"
     aSDomain        complement(11775..12269)
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_PKS_DH.1"
                     /evalue="5.10E-48"
                     /label="IE274_RS38495_PKS_DH.1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="2144"
                     /protein_start="1979"
                     /score="155.5"
                     /tool="antismash"
                     /translation="HPLLGQAVELAGGQGWLFTGDIDPDAHRWLADHTLLGQPLLPGAA
                     VAELALYAGRKSGAERVGDIALERPLPLSEPMGLQLMVGPADADGSRAFTLYARPRAAV
                     KDDWKRHAAGVLEVAGPTAAPEGSAALALWPPLDAAPVPVDGRYAELAERGYEYGPAFQ
                     GL"
     CDS_motif       complement(12111..12185)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0024"
                     /evalue="2.50E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE274_RS38495"
                     /protein_end="2032"
                     /protein_start="2007"
                     /score="26.4"
                     /tool="antismash"
                     /translation="WLADHTLLGQPLLPGAAVAELALYA"
     aSDomain        complement(12474..13355)
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_PKS_AT.2"
                     /evalue="1.70E-104"
                     /label="IE274_RS38495_PKS_AT.2"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1911"
                     /protein_start="1617"
                     /score="341.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQRLGMGRELYEHSPAFAAALDTVCAHLDPHLPHAVRDV
                     VFAAEGSDEAALLDQTLYTQAALFAVEVALFRLMELSGLRADYLIGHSVGELAAAHAAG
                     VLGLADACALVAARGRLMQAAPDGGAMVAVEATEEEVRAALPRYAGRLDVAALNGPLAA
                     VVAGDEGAALALAAAFEEQGRRTSRLKVSHAFHSHHMDGVLDEFRAVAAGLTYAAPRIP
                     VVSNLTGALATPEELASPDYWTSHLRGAVRFQDGVRVLHEAGVTAYVELGPDAVLAAMV
                     RNCLGEERAEAAA"
     CDS_motif       complement(12597..12632)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0023"
                     /evalue="3.40E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1870"
                     /protein_start="1858"
                     /score="11.0"
                     /tool="antismash"
                     /translation="YWTSHLRGAVRF"
     CDS_motif       complement(12669..12701)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0022"
                     /evalue="1.60E-02"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1846"
                     /protein_start="1835"
                     /score="8.3"
                     /tool="antismash"
                     /translation="PRIPVVSNLTG"
     CDS_motif       complement(12855..12893)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0021"
                     /evalue="8.50E-02"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1784"
                     /protein_start="1771"
                     /score="6.5"
                     /tool="antismash"
                     /translation="AALNGPLAAVVAG"
     CDS_motif       complement(12987..13097)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0020"
                     /evalue="9.30E-19"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1740"
                     /protein_start="1703"
                     /score="59.6"
                     /tool="antismash"
                     /translation="DYLIGHSVGELAAAHAAGVLGLADACALVAARGRLMQ"
     CDS_motif       complement(13122..13166)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0019"
                     /evalue="1.00E-01"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1695"
                     /protein_start="1680"
                     /score="6.3"
                     /tool="antismash"
                     /translation="TQAALFAVEVALFRL"
     CDS_motif       complement(13305..13352)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0018"
                     /evalue="1.50E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1634"
                     /protein_start="1618"
                     /score="17.5"
                     /tool="antismash"
                     /translation="FTGQGSQRLGMGRELY"
     aSDomain        complement(13701..14978)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.70E-176"
                     /label="IE274_RS38495_PKS_KS.2"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1502"
                     /protein_start="1076"
                     /score="578.6"
                     /tool="antismash"
                     /translation="IVIVSMACRFPGGVASPEDLWQLVLDGRDAISPFPENRGWPLGAL
                     FDDDPDRAGRSYAREGGFLHDADLFDAEFFGISPREATGLDPQQRLVLETVWETVERSG
                     IDPAELRGSDTGVYVGAMKQDYGPRLDADDDTASGYLLTGSFTSLVSGRAAYTFGLQGP
                     AVTVDTACSSSLVAVHMAARALRDGECDLAFAGGVTVMSSPGMFTEFSRQRGLSPDGRC
                     KAFADSADGTGWAEGAGMLMLERLSDARRRGHEVLAVVRGSALSQDGASNGLTAPNGLS
                     QERVILDALAGADLTVADVDVVEAHGTGTTLGDPIEAQALLATYGRRAGAVEPLYLGSL
                     KSNVGHAQAAAGVGGLIKMVLAMRHGVLPRTLHIDAPSSHVDWTSGAVALLTEARPWPE
                     TGRARRAGISSFGISGTNAHVIVEQAP"
     CDS_motif       complement(13923..13967)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0017"
                     /evalue="1.10E-02"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1428"
                     /protein_start="1413"
                     /score="8.8"
                     /tool="antismash"
                     /translation="GSLKSNVGHAQAAAG"
     CDS_motif       complement(14028..14072)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0016"
                     /evalue="7.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1393"
                     /protein_start="1378"
                     /score="12.0"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       complement(14268..14306)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0015"
                     /evalue="1.10E+00"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1313"
                     /protein_start="1300"
                     /score="3.4"
                     /tool="antismash"
                     /translation="FADSADGTGWAEG"
     CDS_motif       complement(14448..14495)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0014"
                     /evalue="1.50E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1253"
                     /protein_start="1237"
                     /score="20.1"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       complement(14697..14723)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0013"
                     /evalue="1.20E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1170"
                     /protein_start="1161"
                     /score="5.9"
                     /tool="antismash"
                     /translation="DPQQRLVLE"
     aSDomain        complement(15054..15269)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_ACP.1"
                     /evalue="1.40E-27"
                     /label="IE274_RS38495_ACP.1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="1051"
                     /protein_start="979"
                     /score="87.8"
                     /tool="antismash"
                     /translation="LDLVRAEAALVLGHDGGDDVDPESAFTDLGFESVTAVEMRDRLVA
                     ATGLKLPATLLFNHPTPRHLAARVAGE"
     aSModule        complement(15054..18158)
                     /complete
                     /domains="nrpspksdomains_IE274_RS38495_PKS_KS.1"
                     /domains="nrpspksdomains_IE274_RS38495_PKS_AT.1"
                     /domains="nrpspksdomains_IE274_RS38495_ACP.1"
                     /locus_tags="IE274_RS38495"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(15612..16499)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_PKS_AT.1"
                     /evalue="1.80E-96"
                     /label="IE274_RS38495_PKS_AT.1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="865"
                     /protein_start="569"
                     /score="314.9"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGPQWTGMAGDLLDASEVFRARFDECAAALAPHIDWDLEAV
                     LRDAPGAASLEREDVAQPALFAVMVSLAALWQSFGVRPAAVVGHSNGEISAAVVAGALS
                     LEDGARVVARWSRAMLAVVGRGTMLSVPLPVAEVTPRLSAWEGRLFVSAINGPRLFTLS
                     GDVEAIEALRAELVAEGVQARRVPIGLAPHCAWMEVLREEILGLLAPIRPRTPTLPMYS
                     TITGALVDGPVLDGAYWMSNLTSTVDFERTVRELAPETGAFVEIAPHPVLGMALRQITE
                     DVGSDAAVVGTLRRG"
     CDS_motif       complement(15753..15800)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0012"
                     /evalue="1.30E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE274_RS38495"
                     /protein_end="818"
                     /protein_start="802"
                     /score="11.4"
                     /tool="antismash"
                     /translation="LDGAYWMSNLTSTVDF"
     CDS_motif       complement(15822..15854)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0011"
                     /evalue="1.40E+00"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="IE274_RS38495"
                     /protein_end="795"
                     /protein_start="784"
                     /score="2.7"
                     /tool="antismash"
                     /translation="PTLPMYSTITG"
     CDS_motif       complement(16008..16043)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0010"
                     /evalue="1.10E+00"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE274_RS38495"
                     /protein_end="733"
                     /protein_start="721"
                     /score="3.1"
                     /tool="antismash"
                     /translation="AINGPRLFTLSG"
     CDS_motif       complement(16155..16262)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0009"
                     /evalue="1.10E-16"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE274_RS38495"
                     /protein_end="684"
                     /protein_start="648"
                     /score="52.7"
                     /tool="antismash"
                     /translation="GVRPAAVVGHSNGEISAAVVAGALSLEDGARVVARW"
     CDS_motif       complement(16266..16334)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0008"
                     /evalue="3.40E-09"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE274_RS38495"
                     /protein_end="647"
                     /protein_start="624"
                     /score="28.9"
                     /tool="antismash"
                     /translation="EREDVAQPALFAVMVSLAALWQS"
     CDS_motif       complement(16449..16505)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0007"
                     /evalue="7.80E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="586"
                     /protein_start="567"
                     /score="24.3"
                     /tool="antismash"
                     /translation="VFVFPGQGPQWTGMAGDLL"
     CDS_motif       complement(16866..16895)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0006"
                     /evalue="3.20E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE274_RS38495"
                     /protein_end="447"
                     /protein_start="437"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="GAEGAARAEG"
     aSDomain        complement(16899..18158)
                     /ASF="found active site cysteine: False, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS38495_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.70E-164"
                     /label="IE274_RS38495_PKS_KS.1"
                     /locus_tag="IE274_RS38495"
                     /protein_end="436"
                     /protein_start="16"
                     /score="539.7"
                     /tool="antismash"
                     /translation="IAVVGMSCRFPGAPDPEAYWRLLVTGRDAVTDTPAERAELGLGIE
                     HGPAGKGAFLDGIDRFDPGFFAIPPREAAMMDPQQRLVLELGWEALEQAGVVPAGLQGG
                     DTGIFLGATTGDYADLVHRSAGDGSNVTHHSFTGLDRSLIANRVSYVLGLRGPSLTVDA
                     GQASSLVAVHMACQSLRNGESEVALAGGVELHLAPEKTALAQKFGGLSPDGRCYTFDAR
                     ANGYVRGEGGAVVVLKTLRRALADGDRVHAVLRGSAVNNDGGGAGLTVPHEDAQRDLLR
                     RAHERAGTAPADVGYVELHGTGTPVGDPVEAAALGAVLGAARPDGEPLLVGSVKTNIGH
                     LGAAAGMAGLLKVVLSLTHGRLPPSLHYRSPNPRIPMAELNLRVQDAVGDWPGAGAQRL
                     AGVSSFSVGGTNCHVVVSSAP"
     CDS_motif       complement(17121..17165)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0005"
                     /evalue="5.90E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE274_RS38495"
                     /protein_end="362"
                     /protein_start="347"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GSVKTNIGHLGAAAG"
     CDS_motif       complement(17226..17273)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0004"
                     /evalue="9.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE274_RS38495"
                     /protein_end="327"
                     /protein_start="311"
                     /score="11.7"
                     /tool="antismash"
                     /translation="YVELHGTGTPVGDPVE"
     CDS_motif       complement(17466..17504)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0003"
                     /evalue="1.00E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE274_RS38495"
                     /protein_end="247"
                     /protein_start="234"
                     /score="15.2"
                     /tool="antismash"
                     /translation="FDARANGYVRGEG"
     CDS_motif       complement(17646..17693)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0002"
                     /evalue="1.90E-02"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE274_RS38495"
                     /protein_end="187"
                     /protein_start="171"
                     /score="8.0"
                     /tool="antismash"
                     /translation="GPSLTVDAGQASSLVA"
     CDS_motif       complement(17904..17930)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS38495_0001"
                     /evalue="1.20E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE274_RS38495"
                     /protein_end="101"
                     /protein_start="92"
                     /score="5.9"
                     /tool="antismash"
                     /translation="DPQQRLVLE"
     gene            complement(18313..19476)
                     /locus_tag="IE274_RS38500"
                     /old_locus_tag="GCM10010349_78640"
     CDS             complement(18313..19476)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645774.1"
                     /locus_tag="IE274_RS38500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78640"
                     /product="cytochrome P450"
                     /protein_id="WP_229910110.1"
                     /sec_met_domain="p450 (E-value: 1.2e-22, bitscore: 69.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQCPYHRMGPLPDFFEPGEEDVKQIVTSAGDKMWLVRDYALSRL
                     VLADKRFSRAAAVAPGAPMFNDAQPVAESMVSMDGAEHARLRRTVIGAFTARKMAAMAP
                     GITAVTDRCLDALEERGPGADLVAGLADPLPLDVLCQLLGIPLDDGAKFRDWVEVLFDI
                     SASSPQEKARKRLELSGYMADLLATKRRAPADDLLSSLIQAQDRGELTPGELITLGLTL
                     LMAGYETTVGQIALSAHVLLSDPAGYRDLVEHPERVDAAVEELMRLTPATPLSFSRVAT
                     EPVRLGSVQVQAGEALMVSLLNGNRDAEVYPEPDRLEPEGRDSVHLTFGHGLHRCLGAP
                     LGRIQLQVVFRRLVERFPGLRFADVPEPVVWKDGMGTRGLSRLLVAW"
     misc_feature    19864..19877
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.53"
                     /tool="antismash"
     misc_feature    complement(19954..19971)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 18.25"
                     /tool="antismash"
     misc_feature    20174..20192
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.52"
                     /tool="antismash"
     misc_feature    20177..20190
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.06"
                     /tool="antismash"
     gene            complement(20279..20980)
                     /locus_tag="IE274_RS38505"
                     /old_locus_tag="GCM10010349_78650"
     CDS             complement(20279..20980)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845960.1"
                     /locus_tag="IE274_RS38505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78650"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_229910111.1"
                     /transl_table=11
                     /translation="MTPALTAPPVQTQTPTQPLTPVQVQVQTPALTKTPAPETAPTPAP
                     TRPRTRRTDAADEPVTRLALAARDGDPEAVERFVRALHRDVLRYVAHLSADPQAADDLA
                     QDTFLRALGSLHRFEGRSSARTWLLSIARRTVVDSLRHAAARPRLSDRDDWQAAAEQAQ
                     PRGLPGFDDGIALAELLDGIPAERREAFVLTQLLQQPYAEAAAAIGCPIGTVRSRVARA
                     RATLIEALAAA"
     gene            complement(21305..22192)
                     /locus_tag="IE274_RS38510"
                     /old_locus_tag="GCM10010349_78660"
     CDS             complement(21305..22192)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152482.1"
                     /locus_tag="IE274_RS38510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_78660"
                     /product="hypothetical protein"
                     /protein_id="WP_190120607.1"
                     /transl_table=11
                     /translation="MTGGRSCRAVRAAVFAAACVLLAATGHALMSSAPLPWWALPGAGG
                     VTFAGAWLLTGRERGVLAVTTASVVAQAALHTWFSLVQAMTQSSASGGASLAQQWARHL
                     LCGAGGTGMLPEADAVRAVTDAGLADRLHGPPPGHTQHSMGMQETVGAGTSGASGAGGA
                     HASMGHGMSGMHDASSAAPGTDSGMPDMTGMGGMHSGHDMGGMSPLGMLAAHLLAALLC
                     GLWLAYGERAAFRVGRAFAGWLVAPLRLVLRLPRPPHRPRLRPRRDFGARNARRLLLVH
                     AITSRGPPLGIAVV"
     misc_feature    22307..22322
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.08"
                     /tool="antismash"
ORIGIN
        1 agcgggtcgg cgtcgacgac aacttcttca ccgtcggtgg ccactccctg ctcgccaccc
       61 ggctcgtcag ccggatccgt acggtgctcg gcgtcgagat cccgatgcgc gtcgtgttcc
      121 agtacgccac cgtcgcggag atggccgact gcctcacctc gggcaaggag tcgttcagcc
      181 tcaccgaccc gttcggcgtg gtcctgccga tgaagaccga cggcgacgcg ggacccctgt
      241 ggttcgtcca ccccggtgtg ggcctctcct gggtctacct cggcttcgcc acgcagctcg
      301 gcgaccggcc ggtgtacggc atccaggcgc gcggcttcga cggctccgaa ctgccgggct
      361 ccatcgacga gatggtggcc gactacctgg agcagatcct cgccgtgcag ccgcagggcc
      421 ccttccggct ggtcggcctg tccatcggcg gcaccctggc gcacgccctc gcgggcgaac
      481 tgcaggcgcg cggccacgag gtggcactgc tcggcctcct cgactgcgtg cccgcggagt
      541 ggttcgcgcg gaaccacacg tccctggaga cggccgaggt ggcggacgtg ctcgccggat
      601 acatcccgca cacggcaccg aagggcggcg accccgccga cggggccgag gacggtgagc
      661 ggaactcgct cgtgcggaac gcgtccgcca tcgccgtccg gcacaccgac atgatgaggg
      721 cgtacacgca gccgacgtac cgaggcgacg cggtgttctt caacgcgacg ctgaaccccg
      781 acgagacgta cgcaccgcag tgggcggcgt acatcgaggg aacggtggcg gagcacgacg
      841 tccacgccac gcacctgggg atgtgccggc cgcgtcccgc ggcggagatc tgccgggtcc
      901 tcagccgtca cctcgacagc gagtagggag cgggccgtac gacaccacgg aggggcgagg
      961 ccgtccggcc ccgcccctcc gggacaacac acctagggcg cgagcggccc cgacgggacc
     1021 accaggtccc gggtgatgtc cgcgacgctc cggctcccgg tgagggccag cgccaggtcc
     1081 aggtcggcga gcaggcaccg caggacgtgc tccacccccg cctgcccggc cagcgcgaga
     1141 ccgtacaggt acggcctgcc gagcaggatc gcgtccgcgc cgagcgcgag cgccttgacc
     1201 acgtccgtgc ccgtgcgcac gcccgagtcc atcaggaccg ggacgtcggg cccgagggcc
     1261 gcgcgcaccg cgggcagcac gtcgagcgcg gccacaccgc cgtccaactg gcggccgccg
     1321 tggttggaga ccacgacacc gttggcgccg gacgcgagcg ccttgcgggc gtcgtccggg
     1381 tgctggatgc ccttgatgag gatcggcagc gtcgtccacg accgcaggcg cggcagatcg
     1441 tcccaggtga gcgccgggtt ggacgagatc ttcgcccagt gcccggcggc cgccagcggc
     1501 ccgccgtcct ccggcagccc ggctcggaag gccgggtcgc tggtgaagtt ggcgatgccg
     1561 tggccgtgca cgaacgggat gtacgcggtg tccatgtcgc agggccggta gccgaaggcg
     1621 gggttgtcca ccgtgaccac gatcgccgcg tacccggccg attcgacccg acggaccagg
     1681 gactcggcca ccgccgggtc gttcggccag tacaactggt accagcgcgg ctcgctcccg
     1741 gccgccttcg ccacgtcctc catggagtgc gaggagaccg acgacaggac gaacggcaga
     1801 ccgacgtcgg cggcggcgcg gaccgaggcc agctcgccct cggggtgcgc caccgtctgc
     1861 gcggccaccg gcgcgagcag caccggcgcg tccaggcgct gcccgaacag ggtcaccgac
     1921 aggtcccgct cgctgacccc cgtccacatc cgcggcagca gccgccaccg ctcgaacgcc
     1981 tcgcggttgg cgcggccggt cgtgccggtg cccgcgttgc ccgcgatgta ggcgtacgcg
     2041 tgcggttcga ggaccgcgcg cgccgcctcc tccagtgatg tcaggtccgt ggacagctcc
     2101 ggcttgtgcc cggagatacc ggccaggtag atctgccgga ccagctcggc acgggccgcc
     2161 cccggcgccc ccgtctgctc gctcatgcgc cgaccacctg tccggtcgtg ccggtggccg
     2221 cggcccgccg caggtcctcg cggatgacgc gggtgagcag cgggacgacc gtcgggccgg
     2281 gctcggtcag ggcgaagtgg ccgccgggca gcagctccag gccgtactcg cccgtggtgt
     2341 gccgctccca gtcggccagc tgcccggccg tgttcttcgg gtcgtcccgc gcgagcagga
     2401 ccgtcagcgg ggccgtcacg gcggcgccgt ccgcggcctg gtagcggccg aggacctcct
     2461 ggtcgccgcg caggaggcgc gtcatctcgg cgaccgtctc cgggtcgtcg agaagggcgt
     2521 ccggtacgcc gccgagccac cggacgtggc cgaggagctc ctcgtcggag tgcacgccgc
     2581 cggcgtgcgc ccgccagtcc gccgacggcg gccacgccgc cgaggcgaag agccgggcca
     2641 gaccggcccg ctcctcgagg agacgggccg actcgaaggc cacgagcgcg ccgaagctgt
     2701 gcccgagcag gaacagcgga cggtcgtcga acgcggcgag cgcgtccacg acacccgccg
     2761 cgagcgtcgt cacgtcctcg gcgaacggct cggccctgcg gtcctgccgc cccgggtact
     2821 gcacggccag cagctcgacg tcagcgggca gcgccgccga cagcgcggtg aacgcgagcg
     2881 cggggccccc ggcgtgcggg aagcacacca ggcgggcccg ggcgtcgggc ttcgcatgga
     2941 acgtacgaat ccatttcttg cgactcatgt gatggggttc tcttcctcaa gagccgagct
     3001 tggtcagcag ggcggtcaga cggtcggtca cggtgtcgcg caccgcgtca ccgagctgag
     3061 ccccggtgac ctcggcgaac accgactcca gctgggtgat cccgtcgagc agggcctgcg
     3121 ggccccggtc gggatccgcc gggcgcgcgg cggcgccgtc ggcccccgcg gcgcctgtga
     3181 cgcgtccctg ctccgccttc aggtgcgcca ccagctcggt cgtggtcggc cagtcgtaga
     3241 tgaaggtggc gggcagtttc acaccggtgg cggcgccgag ccggttgcgc agctccaccg
     3301 ccgtcagcga gtcgaacccg atctggtcga aggcgccgtg cgggtcgacg accgcgccgg
     3361 aggcgtggcc gaggacggcc gcgacctcct gcaggaccgt gtccaggagc cggtcgccgg
     3421 tgcccgcgct cgccgccggg gcgtcggccg tggcggcctc ggccccgcgg gcgggggccg
     3481 ggaccaggtt ctcgagcagc gcggggacgg tgccgccggt cgcgagccgg tcgcgcagcc
     3541 ccgccaggtg ccacgcggcg gccacggcca cgggggcgtc cctgcggacc gccgcgtcga
     3601 gcagttcgag gccccgctcc ggcgtcagcg gcgccacccc gatacggctc aggcgggtga
     3661 ggtcggtgtc ggtcagcccg gcgcccatgc cgccgacgcc ctcccacaga ccccacgcga
     3721 tcgacacgcc gggcctgccg atcgaccgcc ggtactcgac gaggccgtcg aggaaggagt
     3781 tgcccgccgc gtaaccgccc tgcgcgggcg agcccatggt gcccgcgagc gaggagaaca
     3841 gcacgaacgc gtccaggccc aggtgctccg tcagctcgtg caggtggagc gccgcgtcca
     3901 ccttcgggcg cagcgaccgg tccaggctct ccggggtcag gtcggcgagg atgccgtcgt
     3961 ccaggacacc ggccgcgtgc aggacgctgc cgacgcgcac gccgtccgcc gcgagaccgg
     4021 ccagggccgc ggccagcgcg tcccggtccg ccgcgtcgca cgccaccacc cgcacgtcca
     4081 cgccccgcgc acgcagctcg tcgatgtcgc gccgcgcgtc ctgcgtcggc gcgccccggc
     4141 ccatcaggac cacgctgcgc acgccgtgct cggccacgag gtgccgggcg acgagacggc
     4201 cgagccagcc cagaccgccg gtgacgaggg cggcgcgggt ggtgtcgtac ggctcgtccg
     4261 ggtcggacag ggcaaggacg accttgccga tgtgccgggc ctcgctcagg tagcggaacg
     4321 cgtcgggggc gcgccggatg tcccacaccg agatcggcgg ggcctgcagg gcgccctgca
     4381 ggaacagctc caggagttcc tggagcatgc cctggatgcg gtccgggccg ggctcgcgca
     4441 cgtcgtacgc gcggtagtcg acgcccgggt gccgggcgcc gacctcggcc gggtcgcgcc
     4501 ggtccgtctt gcccatctcc aggaaccggc cgccgcgcgg gagaaggcgc agcgacgcgt
     4561 cggcgaactc gcccgcgagg gagttcagga cgacgtcgac gccctggccg ccggagacgc
     4621 cgaggaagga ctgctcgaag tcgagcgtgc gggaggaggc gatgcgctcc tcggcgacgc
     4681 ccgcggcgcg cagcgcgtcc cacttgcccc ggctcgccgt cgcgtagacg gtcgcgccca
     4741 ggtgctcggc gatctggacg gccgcggtgc cgacgccgcc ggcgcccgcg tggacgagga
     4801 ccgactcgcc cgcaccgagg cgggccaggt ccaccaggcc gtagtacgcg gtcaggtagg
     4861 tcaccgggac cgcggcggcc tgccggaacg accagccgtc ggggatccgg cacaccaggc
     4921 ggtggtcggt caccgtgttc gggccgatgc cgttgatgag gcccatgacg cggtcgccgg
     4981 gcttgaggtc cgtgacgccg gggccgacct cgacgacgac tcccgcgccc tcgccgccac
     5041 cgccgttgtc ggacgcgtcc gcgtcgacgg aggcgtggat gacgccgagc gcgagcagcg
     5101 cctcacggaa gttcagaccg gcggcgcgca ggcgcagccg gatctggccc tccttgagcg
     5161 gttcggcgat ctccggccac ggctcgaagg acaggttcgc gaacgacgac ttggcgacgt
     5221 agtccaggta ccagttcggc tcgttcggcg gcgggcgcag cgtgctgccc ggggccgtgg
     5281 tgctcagggc cgggcggtag gcggtgccgc cgcgcagcgc gagctgcggc tcggcggcgg
     5341 cgacggcgcc cgcgagcgcc gcgcgggaac cggccgtgcc gtcctcgtcc aggagcgcga
     5401 agcggcccgg gtgctcggcg atcgccgacc gcagcaggcc ccacacggac cgcgggccga
     5461 gccgtccggt cggctgctcg gcgtccaccg cgaccgcgcc gcgcgtgacg gccaccaggc
     5521 gcgtcgccga caggcggtcg tcggcgagga cgagttgagc ggtcgtcagg acgtgccgca
     5581 gggagtcccg gacggccgcc gggtccggta tcccgtcggc gcggcccgcc gcgacgggca
     5641 gcaggatgac ctcgggagcc tcctcgccct cgtccagggc ctcggacaag gacgcctgat
     5701 cggcgaagcg gcgcgtgacg acgccgtgcg gcgcctcgtc cgcgaagtcg ccgaggacgg
     5761 cccacagttc cgtgtcgccg gcggcgggca gctccgaaag ggcctcccac gacggcacgt
     5821 acagcccgtc gcggtcgctc gccgaggccg tggcggccgg gcgcagcgcc agcgagccga
     5881 tggcggccac gggcttgccc gcggcgtcgg ccacgtccac ggagatcgcg tttcggcccg
     5941 ccggggccag ccgcacgcgc agcgcggcgt cggcggtgcc cagggtgcgg gcgttgctcc
     6001 aggcgtacgg cagcagcgtc ctgccgcccg gactgtcggt caggccaccg gccgccgacg
     6061 ggtgcagggc cgcgtcgagc agcgccgggt gcaggccgta gccgcccgcg ccgggctgct
     6121 tgccgtccgg cagcgccacc tcggcgaaca cctcgtcgcc gcgctggtac accgccttga
     6181 cgccacggaa caccgggccg tacgacaggc ccttcgcggc caggtcggcg tacaggtcgt
     6241 cgggggcgac cgccagctcc tcggcgccct gcggcggcca caccgtgagg tcggccgggg
     6301 ccgcctcggc ggtggccccg gcgacggagc cgctggcgtt gcgcagccag ccgccgaggt
     6361 cggtgtcgtc ctcgcggcgc gagtggaccg tcaccgcacg gctgccggtg gcgtccgggg
     6421 ccgagaggaa cacccgcagc tgcacctcgg tgtcctcggc gacgatcagc ggcgcctcca
     6481 ggagcagctc ttccacgacg tcgcagcccg ccgcacgtgc ggagcgcgcg gccaggtcga
     6541 gcagggccgt gcccggcacc aggacctggt cgccgacctt gtggtcggcc agccacgcgt
     6601 gcgtggccag ggagaggcgg ccggtgagca acaggccgtc cggctcgggg agttcggcga
     6661 cggccgtcag cgtcggatgg tcgagcgcga ccagaccggc cgagcgcacg tcaccgggga
     6721 cgacgcgctt gtcgagccag tacgggcggc gctggaaggc gtacgtcggc agctcgacgc
     6781 ggtgcgcgcc gtggcccgcg aacaccgcgg cccagtcgac gtcgccgccg ctggtgtggg
     6841 tgcggccgag cgcggtgagc agcgtcccgg tctccgggtg gcggcggcgc agcgagggga
     6901 tcagctcgtg cgcggtgcgc tgcccggcga ggcagtccgc ggccatcgcg gtgaggtcgc
     6961 cggacgggcc cagctccagg aaccggacgc agccgtcggc ggcgaggccg cgcacaccgt
     7021 cctggaagcg gacggtgctc agcaggtgcc gcgcccagta gtcggggtcg gcgagttcgt
     7081 cgggctccac ggcacgcccg gtgaggtccg agacgaccgt cagctccggg gagcggaact
     7141 ccaggctcgc ggcgagcgcg cggaactcgg cgagggccgg ctccatcagc ggggagtgga
     7201 aggcatggct gacgttcagc ctggtcgcct tgccaccggc ctcctcgaac ggcctgacgg
     7261 cggcggccag cgcctccttg tcgccggaca gcacggtcgc ggcggggccg ttgacggcgg
     7321 cgagggacac cttgcccgca tacccggcga ggagcccgac cgcctcctcc tcggaggtgc
     7381 gcagcgccac catggcgccg cccgcgggca gtcgctgcat gatccggccg cgggcgacgg
     7441 ccagctgtgc ggcgtccgcc agcgagagca ccccggccgc gtgcacggcc gcgaacgcgc
     7501 cgaccgagtg gccgagcacc gcgtccgggc ggatgcccca cgactcgaag agccggaaca
     7561 gcgccacctc gacggcgaac agcgcgggct gggtgtactc ggtgcggttc aggaggtcgg
     7621 ccgtgggcgt gccctcggcg gcgaggacca cctcggccag cggctcggcc agctgcgggt
     7681 cgaccaccgc gcacaccgcg tcgaaggccg cggcgtacgc ggggaacgcc tcgtacaagt
     7741 ccttgcccat gcccggacgc tgagagccct gaccggcgaa caggaacgcg gtgcggccct
     7801 cggccgcctt gccgcgcacg acctcggggt ccgccgcgtc gtcggcgagg gcgcgcaacc
     7861 gcgtcagcag ggacgcgcgg tcggcggccg tcaggaccgc gcggtgcgcc aggtgggcgc
     7921 gcgtggtggc aagggacagg ccgagcggcg cgaggccgtc ggcggtcacc gacggctcgg
     7981 ccgtcaggtg ctggtgcagc cggtcggcct gggcgcgcag ggcggcctcg gtggcggccg
     8041 acaggacgtg cggcacggcg ggcagcgact tgccggcccg ctcctcggcg ggccgttcga
     8101 cgggctcggg ggcctgctcc aggatgacgt gcgcgttggt gccgccgatg ccgaaggagg
     8161 acacggccgc gcgccggggg cggtcgaccc gcggccacgc cttggcctcc gtcagcagct
     8221 ccagggtgcc cgtggaccag tcgacgttcg ggctgggctc gtccacgtgc agcgtcttgg
     8281 gcagcacgcc gtgccgcagc gccatcgtca gcttgatgag gccaccgact ccggcggccg
     8341 cctgggcgtg cccgatgttc gacttcagcg agccgaggta cagcgggttg gccgaggtgc
     8401 gggccgcgcc gtacgtggcg agcagcgcgt tcgcctccag cgggtccccg agcggggtgc
     8461 cggtgccgtg cgcctccagg aggtccacgt cggcgccgct cagaccggca ccggccaggg
     8521 cctgcttgat cagggcttcc tgggcggggc cgttgggcgc cgtcaggccg ttgctcgcgc
     8581 cgtcctggtt gacggccgag ccgcgcacca ccgcgaggac ggggtggccg aggcggcggg
     8641 cgtcggagag gcgctcgacg agcagcaggc ccgcgccctc cgcccaggcg gtgccgtcgg
     8701 cggccgccgc gaaggacttg cagcggccgt ccttggacag gccgcgctgg cggctgaact
     8761 ccacgaagga gttgggggtc gccatcagcg tcgcgccgcc cgcgagggcg agcgagcact
     8821 cgccgcggcg cagcgagtcg acggccaggt gcagcgccac gagcgacgac gagcaggccg
     8881 tgtcgacggt gatcgccgga ccctgcagac cgaaggtgta cgagatccgg ccggaggcca
     8941 cactgccggt gctgccgatg gtcaggtacg cctcgtactc ctccggggcg ggggagaggc
     9001 gcgccgcgta gtcgtcgtac atggtgccga cgaacacgcc ggtgcggctg ccgcgcagcg
     9061 tcgtggggtc gatgcccgcg tgctcgaagg cctcccaggc ggtctccagg aggagccgct
     9121 gctgggggtc gatcgcgtgc gcctcgcgcg gcgagatgcc gaagaactcg gggtcgaacc
     9181 gcgcggcgtc gtagaggaat ccgccctgct cgacgtagga ggtgccggcg tggtcggggt
     9241 ccgggtcgaa caggtgggac aggtcccagc cgcggtcggt ggggaacgcg ccgaccgcgt
     9301 cgacctcgtc ggcgaccagc tgccacaggt cctgcggtga gctgacgccg ccggggaagc
     9361 ggcagcccat gccgacgatc gccatcggtt ccccggcgcg ctcctcggcg cgggcgttcg
     9421 cggccttcag ccgctcgttc tccttcagcg cggcccgcag cgcggcgacg acctgctggg
     9481 gcgatgtgga cgccatcgtg tccctccgtc cgtgtctttc tccacagctc gctgctgggg
     9541 ccgtgtcagg tctcactgtc gcccagagcc aggcggatca agtcgtcggt gtccatgtcg
     9601 tccaggaggc tttcgctcgt ggacgggccg ccgccgaccg gggcgtgccg caggccgtgc
     9661 ggaccggccc cgtccgtcgt gacggacgcc ccggcgggct cgggagtgag cgcgccgagc
     9721 agccactgcg ccagggaacc gggggtcgga tggtcgaaga ccagggtcgg cggcagcgtg
     9781 acaccggtcg cggcgagcag ccggttgcgg agctccaccg cgctcagcga ggtgaggccg
     9841 aggtcctgga agcggcggcc cgccggcacc tgccccggct cctggccgag gaccgcggcg
     9901 acctccgccc ggacgagctg gagcacgagg tgccggtgct cgcgctcggg cgcccggccc
     9961 agcttcccgc gcagttccgc cgccgagtcc cgcgggggcg ccacggccgc cgaccggtgc
    10021 ggggcgaggt gcttgaggac cgcgggggcg gtcgtccggt ccagggcgcg cgggtcgagc
    10081 acgagggccg tgaggaccgg cgcgccgtca ccgagcgccg cgtcgaacag ggcgagcccg
    10141 tcctcggcgg acagcgtccc gatgcccgac cgccgcagcc gcagcaggtc ggcctcgccg
    10201 aggtgtccgg tcagcgccga ctcgtccgcc cacaggcccc acgccacgga cagcgcgggc
    10261 cgcccctcgg cgcggcgccg ctgtgcgagg ccgtccaagt aggcgttggc cgccgcgtag
    10321 ttggcctggc ccggggtgcc gagcgtgccc gcgaacgacg agaacagcac gaacgccgtc
    10381 aggtcgagac cgcgcgtcag ctcgtccaga tgcgcggcac ccgcggcctt gggccgcagg
    10441 accgcgtcca ggcgctccgg ggtgagcgag ccgaggacgg cgtcgtcgag gacaccggca
    10501 gcgtgcacca cacccgtcag cgggtgctcc gccgggatcg cgccgaggac cccggcgagc
    10561 gcggcccggt cggccgtgtc gcaggccgcg acccgtacct cggcgccggc ggcccgcagg
    10621 gaggccacga actcctcggc gcccggggtg ctcatgccgc ggcggccggt cagcaggagc
    10681 cgtcgtacgc cgtgctccat gacgaggtgc cgggccagga ggcggcccag ggtgccgagg
    10741 ccaccggtga tcaggacgtg gctggtggcg tcgaaggccg gggcggcgcc ggtgcgcggc
    10801 tcgtgcctgc gcagcagcgg tgtcgtcacc cgcccggcac gcagcgccag ttgggggtcg
    10861 gcaccggcgg cggcgcggac cacgccgggc ccggactcgg ggcgcccgtc ggtgtcgacg
    10921 agggtgaagc ggccggggtg ctccgtctgc gcggagcgca gcaggcccca caccggggcc
    10981 gcggccaggt cgacgcgctc gtcggcggtg accgcgacgg cccgctcggt caccacggcg
    11041 agccgggagc cggtgaggcg ggggtcggcg aggaaggcct gggccagggc gagggccgcg
    11101 cgggtggcgg cggccggccc cgcggtgggc ccaccgggtt cggtgggccc accggtcgtg
    11161 gcgggcccgc tggtgacggg ctcgctggtg gggcaaccgc tgggtgcggc ggatcccccg
    11221 ggtccggtgg cgacgacgac ggtcggcacc gctgccccgt cgtcgagcgc ccggcgcagt
    11281 ccggccaggt cggggtaggc gtccacggac acccccgtgg cccggaccgc gtccgtcagg
    11341 tgggagcggt cgtgtcccac gaccgcccag gtgcccaccg gggtcgcccc cggcgtccgc
    11401 ggctcggccc agtccagggc gaacagggcc gccccgtcgg ccgacgcggc cgatgcgaga
    11461 gccgctgccg gaagctcgcg caccacgagg gtctcggcgt cgagaaccgg cgtaccggtc
    11521 tcgtcggcga tgtgcacgga gcaggagtcc tctccgtgcc gccggatccg gacgcgcagc
    11581 gcggtcgcgc cgggcgagtg cagggtcagg ccgctccagg cgaacggcac gacaagtcgg
    11641 gtgcccgcgt cgccgaccag ggcctgcagc gcggagtcga gcgcggccgg ttgcagttgg
    11701 aagccgcgtg cgtgcgccgc ggcgggcagc tcgacctcgg cgtacacctc ggcgccccgg
    11761 cgccacatgg cccgcagccc ctggaaggcg ggcccgtact cgtacccgcg ctcggcgagt
    11821 tcggcgtagc ggccgtcgac gggcaccggc gccgcgtcca gcggcggcca cagggccagg
    11881 gccgcggagc cctccggggc ggcggtgggc ccggcgacct ccaggacacc ggcggcgtgc
    11941 cgcttccagt cgtccttcac cgcggcccgg ggccgggcgt agagcgtgaa ggcgcgcgat
    12001 ccgtccgcgt cggccgggcc caccatcaac tgcaggccca tcggctcgga cagcggcagc
    12061 ggccgctcca gggcgatgtc gccgacgcgc tccgcaccgg acttgcgccc cgcgtacagg
    12121 gcgagttcgg cgacggccgc gcccggcagg aggggctggc cgaggagcgt gtggtcggcc
    12181 agccaccggt gcgcgtccgg gtcgatgtcg ccggtgaaca accagccctg gccaccggca
    12241 agttcgacgg cctgaccgag cagcgggtgc ccggtggagt gctgcgcggg cgcgttgccc
    12301 gccgcggtca gccagtagcg ctcgcgctgg aacgcgtacg tgggcaggtc ggtccgcacg
    12361 gcgccgggga agaggcgcgc ggtgtcgagc gcggcgccgc gcagcgcggc gtggccgagc
    12421 gcggcggcga cggtcaggga ctcggacctg cccgtgcgca gcaccgcgac gggcgccgcg
    12481 gcctcggccc gctcttcgcc cagacagttg cggaccatgg cggcgagcac cgcgtccggg
    12541 cccagctcca cgtacgcggt gacgcccgcc tcgtgcagca cccgcacgcc gtcctggaag
    12601 cggacggcgc cgcgcaggtg gctcgtccag tagtcgggcg aggccagctc ctcgggggtg
    12661 gcgagggcgc cggtgaggtt ggagacgacg gggatgcgcg gggcggcgta cgtcaggccc
    12721 gcggcgaccg cgcggaactc gtcgaggacg ccgtccatgt ggtgcgagtg gaaggcgtgg
    12781 ctgaccttca ggcgcgaggt gcggcggccc tgctcctcga aggcggcggc cagcgcgagc
    12841 gcggcgccct cgtcgccggc cacgaccgcg gcgagggggc cgttgagcgc ggcgacgtcc
    12901 aggcgcccgg cgtacctggg cagggccgcg cggacctcct cctccgtggc ctcgacggcg
    12961 accatcgcgc cgccgtccgg cgcggcctgc atcagccggc cgcgggccgc gaccagcgcg
    13021 caggcgtccg cgaggcccag cacgcccgcg gcgtgggcgg cggccagctc gccgacggag
    13081 tgcccgatga ggtagtcggc gcggaggccg ctgagctcca tgaggcggaa cagcgcgacc
    13141 tcgacggcga acagagccgc ctgtgtgtac agcgtctggt cgagcagggc cgcctcgtcg
    13201 ctgccctcgg ccgcgaacac cacgtcccgc accgcgtgcg gcagatgcgg gtcgaggtgc
    13261 gcgcacaccg tgtcgagggc ggcggcgaac gccgggctgt gctcgtacag ttcacgcccc
    13321 atgccgaggc gctgactgcc ctgaccggtg aacaggaacg ccgtcccgcc cttgccggcg
    13381 cggccggtga ccgccttggt gggaacggcg ggcgggccgt gcagcacccc ggcggcggac
    13441 tcgcccgcgg cgagcgcggc caggccccgc aggaagccct cgcggtcctc ggcgacgacg
    13501 gccgcggtgt gcgcgaaccg ggtgcgcgcg gacatcaacg acaggccgat gtcagcgggg
    13561 tcgcgctcgg ggtgcgcggc gacgaagtcc cgcagccggg ccgccccggc gcgcagcgcg
    13621 cccccggtgc ggcccgagag cagccacggc gcggccggga ccggcgcggg cccggcggcg
    13681 cgcggcgcgg gctccacggc gggcgcctgc tccacgatga cgtgggcgtt ggtgccgctg
    13741 atgccgaacg aggagatgcc cgcgcgccgg gcccggccgg tctcgggcca ggggcgcgcc
    13801 tcggtcagga gcgcgacggc gcccgacgtc cagtcgacgt ggctgctggg cgcgtcgatg
    13861 tgcagggtgc gcggcagcac gccgtgccgc atcgcgagga ccatcttgat cagaccgccg
    13921 acgcccgccg cggcctgtgc gtggccgacg ttggacttca gcgagcccag gtacagcggc
    13981 tcgacggcgc ccgcgcgccg cccgtacgtg gcgagcagcg cctgggcctc gatcgggtcg
    14041 cccagggtgg tgccggtgcc gtgcgcctcg acgacgtcca catcggcgac ggtcaggtcc
    14101 gcgcccgcga gcgcgtcgag gatgacgcgc tcctgggaga ggccgttggg ggcggtgaga
    14161 ccgttgctgg cgccgtcctg actgagcgcg gagccgcgca cgaccgcgag gacctcgtga
    14221 ccgcggcggc gcgcgtcgga caggcgctcc agcatcagca tgcccgcgcc ctcggcccag
    14281 ccggtgccgt cggcggagtc ggcgaacgcc ttgcagcgcc cgtcggggga caggccgcgc
    14341 tggcggctga actccgtgaa cattccgggg ctcgacatca cggtgacgcc gcccgcgaac
    14401 gcgaggtcgc actcgccgtc gcgcagcgcc cgcgcggcca tgtgcacggc cacgagcgag
    14461 gaggagcacg cggtgtcgac ggtgacggcg ggaccctgga ggccgaaggt gtacgcggcg
    14521 cggccggaga ccaggctggt gaagctgccg gtgagcagat agccgctcgc ggtgtcgtcg
    14581 tcggcgtcca ggcgggggcc gtagtcctgc ttcatggcgc cgacgtacac gccggtgtcg
    14641 ctgccgcgta gctcggcggg gtcgattccg cttcgctcga cggtctccca caccgtctcc
    14701 aggaccagcc gctgctgcgg gtccaggccg gtggcctcgc gcgggctgat gccgaagaac
    14761 tccgcgtcga acaggtcggc gtcgtgcagg aacccgccct cgcgggcgta ggagcggccc
    14821 gcgcggtccg ggtcgtcgtc gaacagggcg cccagcggcc agccgcggtt ctccgggaac
    14881 ggcgagatgg cgtcgcgccc gtcgaggacg agctgccaca ggtcctccgg cgaggccacg
    14941 ccgccgggga agcggcaggc catggagacg atcacgatcg ggtcatcctc ggcaccgccc
    15001 cgcacggccg ccctgcgccc gctcgccttc ggggcggacg tggtgccgag gatctccccg
    15061 gcgacgcggg cggcgaggtg ccgcggcgtc gggtggttga acaggagcgt ggccgggagc
    15121 ttcaggccgg tcgccgcgac caggcggtcg cgcatctcca cggcggtcac ggactcgaag
    15181 ccgaggtcgg tgaacgcgct ctcggggtcg acgtcgtcgc cgccgtcgtg gccgagcacc
    15241 agggccgcct cggcgcgcac caggtccagg acccgcgcca aggtctcctc cgggcccagc
    15301 ccgcgcagcc ccggcccgtc gtcggccctg gcggcgtcgg actcccggca cgccgcggcc
    15361 gtcgccgccg gtacgaggtc cgcgcgcggc ccgttgtcgg cgggggccga cgccgtggcg
    15421 ggcgcggcct cccccgccgg ggccgcggtg gtgcccgcga cgccctccag ccagtagccg
    15481 cgccgctgga acgcgtacgt cggcagctcc acgacggacg cgtccgcggg gaacgccgga
    15541 cgccaatcca cctccgcgcc actggcgttg agctgtgcca gcgaggtcag gaagcggcgc
    15601 tgcccgtcct cgccgcggcg cagcgtgccg acgacggccg cgtccgagcc gacgtcctcc
    15661 gtgatctgcc gcagcgccat gccgagcacc gggtgcgggg cgatctcgac gaacgcgccg
    15721 gtctcggggg cgagttcccg gacggtgcgc tcgaagtcca cggtgctggt gaggttgctc
    15781 atccagtacg cgccgtcgag caccggcccg tccacgagcg cgccggtgat ggtcgagtac
    15841 atcggcagcg tcggcgtacg cggccggatc ggcgccagca ggccgaggat ctcctcgcgg
    15901 agcacctcca tccacgcgca gtgcggcgcc aggccgatcg ggacgcgccg ggcctgtacg
    15961 ccctcggcga ccagctcggc ccgcagcgcc tcgatcgcct cgacgtcacc ggacagcgtg
    16021 aataggcggg gcccgttgat cgcggagacg aacaggcggc cctcccaggc ggacaggcgc
    16081 ggcgtgacct cggcgaccgg cagcggcacc gagagcatcg tgccccggcc gacgacggcc
    16141 agcatcgccc tgctccaccg cgccaccacc cgcgcgccgt cctccaggga cagtgccccg
    16201 gcgaccacgg cggcgctgat ctcgccgttg ctgtgcccga cgacggcggc cggccgcaca
    16261 ccgaacgact gccacagggc ggcgagggac accatcacgg cgaacagcgc gggctgggcc
    16321 acgtcctcgc gctccaggga ggccgcgccg ggcgcgtccc ggagcacggc ctccaggtcc
    16381 cagtcgatgt gcggcgcgag cgcggccgcg cactcgtcga accgggcccg gaacacctcg
    16441 gaggcgtcga gcaggtcgcc agccatgccg gtccactgcg ggccctggcc ggggaacacg
    16501 aacacgaccc gctcgcgcgc cgtggcggtc ccgctgatcc gcgtggccga acggcggccc
    16561 tcggcgagcg cggccagctc ggcggtcagc tcgtcgcggt cggcaccgag gaggacggcg
    16621 cggtgcttga aggcggtacg cgtggtggcg agcgagagcc cgatgtcacc ggcgctctcc
    16681 gtgccgctct ccaggtgggc gagcagccgc tcggcctggg cgcgcacggc ggcggaggtg
    16741 cggccggaga ggagccaggg gagggtggcg ccgcgcaggg aggcggagac ggcgggcgcc
    16801 gcgtcctgac catccgtcac atcggcggtg gcggcgacgg caccctcgga gtccgcatcc
    16861 gcagcgccct ccgccctcgc agcgccctcg gcaccctccg gcgccgagga caccaccaca
    16921 tggcagttgg tcccgccgac gctgaacgac gagacaccgg cgagccgttg tgcgcccgcg
    16981 ccgggccagt cgcccaccgc gtcctgcacc cgcaggttca actcggccat cgggatgcgg
    17041 gggttgggcg agcggtagtg caggctcggc ggcagccggc cgtgggtgag ggagaggacg
    17101 accttcagga gcccggccat accggccgcg gcgcccaggt gtccgatgtt ggtcttcacg
    17161 gagccgacga gcagcggctc gccgtcgggg cgggcggcgc cgagcacggc gccgagtgcg
    17221 gcggcctcga ccgggtcgcc cacgggggtg ccggtgccgt gcagttcgac gtagccgacg
    17281 tcggcgggcg cggtcccggc ccgctcgtgg gcgcggcgca gcaggtcgcg ctgggcgtcc
    17341 tcgtgcggga cggtgaggcc cgcgccgccg ccgtcgttgt tcacggcgct gccgcgcagc
    17401 acggcgtgca cgcggtcgcc gtcggcgagg gcccgccgca gcgtcttcag gacgacgacg
    17461 gcgccgccct caccgcgtac gtagccgttg gcgcgggcgt cgaaggtgta gcaccggccg
    17521 tcgggggaga ggccgccgaa cttctgggcc agggcggtct tctcgggcgc caggtgcagc
    17581 tcgacgccgc ccgcgagggc gacctcggac tcgccgttgc gcagcgactg gcaggccatg
    17641 tgcacggcga ccagggagga ggcctggccc gcgtcgacgg tcaggctcgg gccgcgcagg
    17701 ccgagcacgt acgagacgcg gttggcgatg aggctgcggt ccaggccggt gaaggagtgg
    17761 tgcgtgacgt tgctgccgtc accggcggag cggtgcacga ggtcggcgta gtcgccggtg
    17821 gtggcgccga ggaagatgcc ggtgtcgccg ccctggaggc cggcggggac caccccggcc
    17881 tgctccaggg cctcccagcc cagttcgagg acgagccgct gctgcgggtc catcatcgcc
    17941 gcctcgcgcg gcgggatggc gaagaagccc gggtcgaagc ggtcgatccc gtcgaggaag
    18001 gcacccttgc cggccggtcc gtgctcgatg ccgaggccga gctccgcgcg ctcggcgggc
    18061 gtgtcggtga cggcgtcccg cccggtcacg agcagccgcc agtacgcctc ggggtcgggg
    18121 gcgccgggga agcggcagga catcccgacg acggctatgg gttccccggc aagccctgca
    18181 tcgctgcggg tgttgtcaac agacatgcca ttcctcactg aaggtcaagc ggtgttcttg
    18241 ggagagccgc catcaggggg cgggcggcgc gcgaccgatg ggctgacggg ctaccgggcc
    18301 actacgcggc ggctaccagg cgacgagcag gcgcgagaga ccgcgggtgc ccatgccgtc
    18361 cttccacacc accggctcgg ggacgtcggc gaagcgcagt ccggggaacc gttcgacgag
    18421 tcggcggaag acgacctgga gctggatccg gccgagcggt gcgccgaggc agcggtgcag
    18481 tccgtggccg aacgtgaggt gcaccgagtc gcggccctcg ggttccaggc ggtcgggctc
    18541 ggggtagacc tcggcgtcgc ggttgccgtt caggagcgac accatcaggg cctcgcccgc
    18601 ctgcacctgg acgctgccga gccgcaccgg ctcggtggcg acgcgggaga agctcagggg
    18661 ggtggcgggg gtgaggcgca tcagctcctc gaccgccgcg tccacgcgct cggggtgctc
    18721 gaccaggtcg cggtaaccgg ccgggtcgga gagcagcacg tgcgcggaga gggcgatctg
    18781 gccgaccgtc gtctcgtagc cggccatcag cagggtcagg ccgagggtga tcagctcgcc
    18841 cggggtcagc tcgccccggt cctgcgcctg gatcagcgag gagagcaggt cgtccgcggg
    18901 cgcgcggcgc ttggtggcga gcaggtcggc catgtagccg ctgagttcga ggcgcttgcg
    18961 ggccttctcc tgcggggagc tggccgagat gtcgaagagc acctcgaccc agtcgcggaa
    19021 cttcgcgccg tcgtccagcg ggatgccgag gagctggcac agcacgtcca gcggcagcgg
    19081 gtcggcgagg cccgccacga ggtcggcgcc gggaccgcgc tcctccaggg cgtccaggca
    19141 gcggtccgtc accgccgtga tgcccggggc catcgcggcc atcttccggg cggtgaacgc
    19201 gccgatgacg gtcctgcgga ggcgggcgtg ctcggcgccg tccatgctca ccatcgactc
    19261 ggccacgggc tgcgcgtcgt tgaacatcgg ggcgcccggc gccacggcgg cggctctgct
    19321 gaaccgcttg tccgcgagga cgagacggct gagcgcgtag tcgcgcacga gccacatctt
    19381 gtcgcccgcc gacgtgacga tctgcttcac gtcctcctcg cccggctcga agaagtccgg
    19441 cagcggaccc atccggtgat aggggcactg cgtcatggtg gtctctcctc cccctggtgg
    19501 gtggctgcca ggtatccgga attcagcgat ccgtttatcg cggtgtcgcg acgccttatc
    19561 gcggtgtcgc gacgccgggg tgccgcggtg tcacggccgc cggacaggcg ccccgcgcac
    19621 cggtccggac gcgaagaggc ccgcagcggg ggcaggccgg ttacgcgtgc gccgaaagag
    19681 ccggaaagcc ggaaggggaa gcatgacgcg attgcgcggt ggcggccacg gccctatccc
    19741 ccttcacctc gaattcactg tgcgcaagcc tcggtcggcc ccgtgaatcc cgctccattc
    19801 cgtaccggga aaagagggcc gctgccgcgc ccgttcgcgg atttccagct ttctggccga
    19861 gctcgaacat acctcccggc cgggaaacgg tgaaccggga acgggagaca gcgggggtag
    19921 tcggcgaggt gctgtcgcgg gtgcgctcgc ggctgtcctg tcaacgggac gggctgcgct
    19981 gtcggtcctc gggtacgggg tccacggggt ccgcgccgag aggcgcgtgg ggccgggcct
    20041 gacgcgcgcg gcactcgttc agttgctctc cggctggttg ctctcgggcg aatcgcgaat
    20101 tccgtatgag cgagtgccgg gaagcctttg acgcattcat gagaaccggc ttcggatgtt
    20161 ctccgctgcg aactccggca tattcattca gcggttcgtg gtggacggcg gagggggtcg
    20221 ccgccgcggg tgcggcggcg accccctccg gatggtgccg acagctcagc tgtctccgtc
    20281 aggccgcggc gagcgcctcg atgagcgtgg cgcgggcccg ggcgacgcgg gagcggaccg
    20341 tgccgatggg acagccgatg gcggcggccg cctccgcgta cggctgctgg agcagttggg
    20401 tgaggacgaa cgcctcgcgc cgctcggccg gtatgccgtc gaggagttcg gcgagcgcga
    20461 tgccgtcgtc gaacccggga agaccgcgcg gctgagcctg ctcggcggcg gcctgccagt
    20521 cgtcgcggtc cgaaaggcgg ggccgcgcgg ccgcgtgccg caggctgtcg acgacggtgc
    20581 gccgcgcgat cgagagcagc caggtacgcg ccgacgaccg cccctcgaac cggtgcaggc
    20641 tgccgagcgc ccgcaggaac gtgtcctgcg cgaggtcgtc ggcggcctgc gggtcggcgc
    20701 tgaggtgcgc gacgtagcgc aggacgtccc ggtgcagagc ccgcacgaaa cgctcgacgg
    20761 cctcggggtc gccgtcacgc gcggcgagag cgagccgcgt gacgggttcg tcggcggcgt
    20821 cggtgcggcg ggtgcggggg cgggtggggg cgggggtggg tgcggtttcc ggtgcgggtg
    20881 tcttggtcag ggccggtgtc tggacctgga cctggaccgg tgtcaggggc tgggtcggtg
    20941 tctgggtctg gacagggggt gccgtcaggg caggagtcat cgcctgaagt ccttatggag
    21001 tccgggagtt cgggatccgg ccgccggggg cgggaccggt gaggtgtcgt acggcccggc
    21061 ggcgctgagg gcggcgcggg ccggtgcccg acgcgctcag ggcgtgcgtg cggcgacgtg
    21121 acgcggtggg gcgtgacgtg gcgggacgcg cgcgggcggt acgcggctcg acggcggggt
    21181 acgacggcac ggggcgcgga gccgtggggc gccgagccgt gcgtgcgaga ggaagccgta
    21241 ccgtgccgtg cggatgccgg gcgagcgccg tgcgttgccg tggcgggtcg ggggaaaccg
    21301 gctgtcagac gacagcgatc ccgaggggcg gacccctgga cgtgatggcg tggacgagga
    21361 gcaggcgccg cgcgttgcgg gcgccgaagt cgcgccgcgg gcgcagccgc ggccggtgcg
    21421 ggggccgcgg caggcgcagg acgagccgca gcggggcgac gagccagccc gcgaaggccc
    21481 ggccgacgcg gaacgcggcg cgctcgccgt acgcgagcca gagcccgcac agaagggcgg
    21541 ccaggaggtg cgcggcgagc atgccgagag gtgacatgcc gcccatgtcg tgaccggagt
    21601 gcatgccgcc catgccggtc atatcgggca tgccggagtc cgtccccggc gcggcacttg
    21661 aggcgtcgtg catgccggac atgccgtgcc ccatggaggc atgggcaccg cccgccccgg
    21721 atgccccgga ggtcccggca ccgacggtct cctgcatgcc catggagtgc tgggtgtgcc
    21781 ccggcggagg tccgtgcagc cggtcggcga ggcccgcgtc ggtgacggcg cgtaccgcgt
    21841 ccgcctccgg cagcatcccc gtaccgcccg ccccgcacag caggtgccgc gcccactgct
    21901 gggcgagcga cgcgccgccg ctcgccgagg actgggtcat cgcctgcacc agcgagaacc
    21961 aggtgtgcag cgcggcctgc gccacgacgg acgccgtggt gacggcgagg acgccgcgct
    22021 cgcgcccggt gaggagccag gcacccgcga acgtcacgcc gcccgcgccg ggcagcgccc
    22081 accagggcag cggcgccgac gacatcaggg cgtgccccgt ggccgcgagc agcacacagg
    22141 cggccgcgaa caccgcagcc cgtaccgcgc gacagcttcg gcccccagtc atggcggcct
    22201 catccttgca tccgcctcac ggcggcaacg ggcgggtccg gaatgttccg tcgggggcgg
    22261 ggtgaggcca ggtgcggcag gggcgggtgc gcgttgcgcc caggggtgtg gccggggtca
    22321 cgaagacgcc cgggaacccg ggagggcgcg gatccgactc ctgcgggagc gcgttgggcg
    22381 acgaccctcg gcgacgcggg agcgggcacc gccgtgcgcg cggactgatc agcacatacg
    22441 agacttcctg ggggcggccg agtggggacg gagcacgcgg ggcgcgggtc ggagcggata
    22501 ggacacgggg cggcggagcc gcatccggag ccgaaaccac acccgcatcc gcatccgcat
    22561 ccgcatccgc atccggagcc gcacccgcat ccggaactgc agtcgcagcc ggagagcacc
    22621 gagccgcagc ccctgccgga ggcacagccg cacctggacg gtgctgggtc gcacctggac
    22681 ggtgctgggt cgcacctgga cgg
//
