LOCUS       NZ_BMVR01000010        26584 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence10, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000010
VERSION     NZ_BMVR01000010.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 373740)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 83066
            Orig. end                         :: 109650
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26584
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26584
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26584
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16584](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16584
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(183..1115)
                     /locus_tag="IE274_RS25630"
                     /old_locus_tag="GCM10010349_52610"
     CDS             complement(183..1115)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="IE274_RS25630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52610"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_190118246.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAPPARGTATAAHKGRLRIALSITLTVMVVEIVGGIV
                     ADSLALIADATHMATDALGLSMALLAIHFANRPPSENRTFGYARAEILAALANCLLLFG
                     VGGYVLYEAVQRFVTPAATEGGLTMVFGLIGLLANLVSLALLMGGQKDSLNVRGAFLEV
                     LADALGSVAVLVSAALILLTGWQAADPIASIVIGLMIVPRTWKLLRETLNVLLESAPKG
                     VDMAEVRAHMLALPGVEDVHDLHAWTITSGMPVLSAHVVVSSEALTAIGHEKMLHELQL
                     CLGDHFDVEHCTFQLEPGGHAEHEPGLCH"
     gene            complement(1287..2267)
                     /gene="galE"
                     /locus_tag="IE274_RS25635"
                     /old_locus_tag="GCM10010349_52620"
     CDS             complement(1287..2267)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-209). E-value: 1e-11.
                     Score: 36.4. Matches aSDomain:
                     nrpspksdomains_IE274_RS25635_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639281.1"
                     /locus_tag="IE274_RS25635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52620"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_190118247.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9e-16, bitscore:
                     51.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3e-12, bitscore:
                     40.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWMITGGAGYIGAHVARVMAGAGERVVVLDDVSSGVPERLPSDI
                     PLVRGTSLDGGLLRRVFAEHAVTGVVHLAARKQVGESVEQPLRYYRENVGGLTTLLEAV
                     VDAGVKRFVFSSSAAVYGNPPDADLVAEDTPCAPVSPYGETKLAGEWLVRAAGRAHGLT
                     TTCLRYFNVAGSASPELADTGVFNVVPMVFDRLTRGEAPRVFGTDHPTPDGTCVRDYIH
                     VGDLAEAHLAAARRPAEPGSDLTVNIGRGEGVSVRELLTVIAEVTGDTREPLLEPRRAG
                     DAPRAVADVRLAAKALGFSARLGVREMVESAWAGWCLRHPEAVRG"
     aSDomain        complement(1641..2072)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS25635_NAD_binding_4.1"
                     /evalue="1.00E-11"
                     /label="IE274_RS25635_NAD_binding_4.1"
                     /locus_tag="IE274_RS25635"
                     /protein_end="209"
                     /protein_start="65"
                     /score="36.4"
                     /tool="antismash"
                     /translation="AVTGVVHLAARKQVGESVEQPLRYYRENVGGLTTLLEAVVDAGVK
                     RFVFSSSAAVYGNPPDADLVAEDTPCAPVSPYGETKLAGEWLVRAAGRAHGLTTTCLRY
                     FNVAGSASPELADTGVFNVVPMVFDRLTRGEAPRVFGTDH"
     CDS_motif       complement(2178..2264)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS25635_0001"
                     /evalue="6.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE274_RS25635"
                     /protein_end="30"
                     /protein_start="1"
                     /score="15.6"
                     /tool="antismash"
                     /translation="TWMITGGAGYIGAHVARVMAGAGERVVVL"
     gene            2523..4382
                     /locus_tag="IE274_RS25640"
                     /old_locus_tag="GCM10010349_52630"
     CDS             2523..4382
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="IE274_RS25640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52630"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_190118412.1"
                     /transl_table=11
                     /translation="MSTAILTGRPVPGSPLEGDLRSLGFDVRTAPEAASPEELEALLRD
                     LPATERVALVDSRFVGHVHALRLGLTDPRFPVSAVPGAMTAQASARRELTAALRTAVGA
                     AGAVEAAAAEATADGGRASVAVASDAVPDRVAAAVEASGTDVHRPELGTLVAALPGDPE
                     SRNSARQAVAAVDDEAVRLRGAVKARDGFFTTYCISPYSRYLARWCARRGLTPNQVTTA
                     SLLVAVIAAGCAATGTRGGFVAAGVLLLFSFVLDCTDGQLARYSLQYSTLGAWLDATFD
                     RAKEYAYYAGLALGAARGGDDVWALALGAMVLQTCRHVVDFSFNEANHDATGNTSPTAA
                     LSDKLDSVGWTVWLRRMIVLPIGERWALIAVLTAVSTPRITLVVLLIGCGLAACYTTAG
                     RVLRSLTRKATRTDRATAALADLADNGPLASAFAALRLRLPLPAPAVAFAGGAAVVCAA
                     LFSSYGSPWVVVGAVVYVIASGLALGRPLKGALDWLVPPFFRVAEYGTVLVLAAKADVN
                     GSLPAAFGLVAAVAYHHYDTVYRIKGGTGAPPRWLVRAIGGQEGRTLAVALAAFALHDT
                     DFTVALTALAVAVALVVLIESIRFWVTAHMRGAPAVHDEGEPA"
     gene            4379..5131
                     /locus_tag="IE274_RS25645"
                     /old_locus_tag="GCM10010349_52640"
     CDS             4379..5131
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="IE274_RS25645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52640"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_190118248.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.4e-10, bitscore:
                     34.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTETLPKALVPVVGEGTENELAVLDLTLK
                     NFAEIGLTEVAIIVGYKKEAVYDRKAALEAKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     IKHDVILANGDTVHPVSVEKTLLAARGDGKKIILALDTVKQLADEEMKVVVDPEKGVQK
                     ITKLMDPAEATGEYIGVTLIEGSAADELADALKTTFERDPDLYYEDGYQELVNRGFKVD
                     VAPIGDVTWVEIDNHDDLAKGREIACQY"
     gene            5119..6183
                     /locus_tag="IE274_RS25650"
                     /old_locus_tag="GCM10010349_52650"
     CDS             5119..6183
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413836.1"
                     /locus_tag="IE274_RS25650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52650"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_190118249.1"
                     /sec_met_domain="Fe-ADH (E-value: 8e-23, bitscore: 74.7,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRAGALNDLAGVLADQRICSSTGKLAIAIS
                     GGSGAVLRKRLAPSLPSAEWFEVGGGTLDDAIKLAEAMKKGRYDAVVGLGGGKIIDCAK
                     FAAARVGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVR
                     FVRSGIGDALSNISAIRDWELAARERGEDIDGLAAAMARQAGEAVLRHPGGVGDDGFLQ
                     VLAEGLVLTGIAMSVSGDSRPASGACHEINHAFDLLFPKRAASHGEQCGLGAAFAMYLR
                     GAREESAYMAEVLRRHGLPVLPEEIGFTVDEFVQVVEYAPQTRPGRYTILEHLNLNTDQ
                     IKDAYADYAKAIGS"
     gene            6161..6940
                     /locus_tag="IE274_RS25655"
                     /old_locus_tag="GCM10010349_52660"
     CDS             6161..6940
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="IE274_RS25655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52660"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_078619253.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPAGVKDRRSGEHWAGRMYMREISLRCDRYLV
                     NTRITPNQLTYLMTVAGVLAAPALLVPGIWGAVLGVVAVQLYLLLDCVDGEIARWRKQY
                     SMSGVYLDRVGAYLCDAAVLVGFGLRAADLWGSGRIDWLWAFLGTLAALGAILIKAETD
                     LVAVARHQQGMAPVQESAAEPRAAGMALARKAAAALKFHRLILGIEASLLILVLAIVDS
                     VRGDLFFSRVGVAVLAGIALLQTLLHLVSILVSSRLK"
     gene            7012..7857
                     /locus_tag="IE274_RS25660"
                     /old_locus_tag="GCM10010349_52670"
     CDS             7012..7857
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983096.1"
                     /locus_tag="IE274_RS25660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52670"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_190118413.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-10,
                     bitscore: 35.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNRPQELRALLDSVAKQDGDRVEVVVVGNGAPVPDVPAGVRTIE
                     LPENLGIPGGRNVGIEAFGPGGTDVDILLFLDDDGLLAHTDTAELCRAAFAADPELGII
                     SFRIADPDTGITQRRHVPRLRASDPMRSSRVTTFLGGANAVRTEVLKEVGGLPDAFFYA
                     HEETDLAWRALDAGWMIDYRADMVLFHPTTAPSRHAVYHRMVARNRVWLARRNLPALLV
                     PVYLGVWLLLTLARRPSRPALKAWFGGFKEGWTSPSGPRRPMKWRTVWRLTRLGRPPVI
                     "
     gene            7956..8885
                     /locus_tag="IE274_RS25665"
                     /old_locus_tag="GCM10010349_52680"
     CDS             7956..8885
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="IE274_RS25665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52680"
                     /product="ABC transporter permease"
                     /protein_id="WP_190118250.1"
                     /transl_table=11
                     /translation="MSETTQDGGVAVTAPPSPDDGLSPAELAAKYGLSVSGARPGLFEY
                     VSQLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNALVYFLIFGLILKADRGMS
                     REVYIPFLVTGVFVFTFTQSSVMAGVRAISGNLGLVRALHFPRASLPVSFSLQQLQQLL
                     FSMIVLFVVAVGFGSYPKLSWLLILPVLALQFLFNTGLALVMARLGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLKEHPAWIGDILQWNPAAIYMDLMRFALIDGYGSENLPPHVW
                     AVAAGWAVLVAVGGFVYFWKAEERYGRG"
     gene            8878..9663
                     /locus_tag="IE274_RS25670"
                     /old_locus_tag="GCM10010349_52690"
     CDS             8878..9663
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534466.1"
                     /locus_tag="IE274_RS25670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52690"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190118251.1"
                     /transl_table=11
                     /translation="MADDKSADRAHIPTVIADELHIVYRVNGAKTGKGSATSALSRIIK
                     RGEERGVRKVHAVRGVSFTAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEKGKVYTDGQ
                     PSLLGVNAALMNDLTGERNVILGGLAMGMSREQIRERYQDIVDFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEARIRELRKEAGSVFLVSH
                     NNKSIRDTCDRVLWLERGELRMDGPTDEVIKEYEKFTGK"
     gene            10001..10900
                     /gene="hpnC"
                     /locus_tag="IE274_RS25675"
                     /old_locus_tag="GCM10010349_52700"
     CDS             10001..10900
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377574.1"
                     /locus_tag="IE274_RS25675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52700"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_190118252.1"
                     /sec_met_domain="phytoene_synt (E-value: 5.6e-40, bitscore:
                     131.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-40,
                     bitscore: 133.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATDDLRLRDASAVLDKAADENFPVAPFFLPRAWREDLMAVYGYA
                     RLVDDIGDTDLDRGAAHARYLGADPEAAGDPLALLDAFEADLNKVFAGQDPGHPLLQAL
                     VPTVRRRGLTPEPFLGLIAANRQDQLVKRYETYDDLLAYCELSANPVGRLVLAITGTAT
                     PERIRLSDSVCTALQIVEHLQDVREDLGRDRVYLPAEDMKRFHVQERDLAVPTAGASVR
                     ALVAYEAERAHGLLNEGTPLVGSVHGRLKLLLAGFVAGGRAAIAAIAAAGYDVLPRPPK
                     PTKPRLVREVGAVLRGEG"
     gene            10897..11847
                     /gene="hpnD"
                     /locus_tag="IE274_RS25680"
                     /old_locus_tag="GCM10010349_52710"
     CDS             10897..11847
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139892.1"
                     /locus_tag="IE274_RS25680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52710"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_190118253.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.1e-56, bitscore:
                     186.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.4e-69,
                     bitscore: 228.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTVESEPRVSAPVLAAYSYCETVTGQQARNFAYGIRLLPTPKR
                     RAMSALYAFSRRVDDIGDGTLAPDVKGARLDDTRALLTRVRDGEVEEDDTDPVAVALSH
                     AAQHFPIPLGGLDELIDGVVMDVRGETYETWEDLKVYCRCVAGAIGRLSLGVFGTEPGA
                     LHAERAPEYADTLGLALQLTNILRDVREDALEGRTYLPADDLAKFGCSAGFSRPEPPAG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIEREPEAVLR
                     GRVSLPGREKAYVAVRGLSGFDARSVSRGAVRRRT"
     gene            11957..13363
                     /gene="hpnE"
                     /locus_tag="IE274_RS25685"
                     /old_locus_tag="GCM10010349_52720"
     CDS             11957..13363
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639271.1"
                     /locus_tag="IE274_RS25685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52720"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_190118254.1"
                     /sec_met_domain="DAO (E-value: 1.3e-10, bitscore: 35.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQDDRQPEGGADGAGKRASAVVVGGGLAGITSALALADAGLDVT
                     LLEGRPRLGGLAFSFQRGELTVDNGQHVYLRCCTAYRWFLDRVEGAHLAPVQDRLDVPV
                     LDADRNRLGRLRRTALPVPLHLAASLAGYPHLSLAERAAVGRAALALKGLDPADPALDS
                     QDFGSWLAARGQSKRAIEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSEPGAADIG
                     WARVPLGDIHDGLARKALDSAGVRTELRARVTSVSRSKNGGWRVEVPGESIPADTVVLA
                     VPQAETHDLLPDGALDEPDRLLGIDTAPILNIHVVYDRKVLRRPFFAALGTPVQWVFDR
                     TEASGLAQGQYLALSQSAAQDEIDAPVAALRERYLPELERLLPAAHGARVLDFFVTRER
                     TATFAPTPGVGRLRPGAHTNASGLYLAGAWTATGWPATMEGAVRSGITAARAALTALDR
                     PHGHLFEEAA"
     gene            13360..14484
                     /locus_tag="IE274_RS25690"
                     /old_locus_tag="GCM10010349_52730"
     CDS             13360..14484
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639270.1"
                     /locus_tag="IE274_RS25690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52730"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_190118255.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.2e-61, bitscore:
                     200.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLDLLGPPPHEPRTGTRGENVPTVPSAEPAAVDVTALLERGRTL
                     ATPVLRSAVDRLAPPMDTVAAYHFGWIDAAGNPAVGDGGKAVRPALALLSAEAAGASPE
                     TGVPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEIL
                     LELGTVEAGRATRRLTTATRALIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAV
                     SIGAVLGGADDATADILEKYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSL
                     PVVAALAAGGPASERLGELLAADAKSNDFDSFSEEEFAARAALIEQAGGREWTAEEARR
                     QHAVAIEALDAVQMPDQVRAQLTALADFVVVRKR"
     gene            14590..16584
                     /gene="shc"
                     /locus_tag="IE274_RS25695"
                     /old_locus_tag="GCM10010349_52740"
     CDS             14590..16584
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656371.1"
                     /locus_tag="IE274_RS25695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52740"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_190118256.1"
                     /sec_met_domain="T2TS (E-value: 2.8e-150, bitscore: 495.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAATPRAASATGTTDTTPAPPGVPGAAARAIERSTQ
                     FLLSRQDAQGWWKGDLATNVTMDAEDLLLRQFLGIQDESTTRAAGLFIRGEQRDDGTWA
                     TFYGGPGELSATIEAYVALRLAGDAPDAPHMAKASAWIRERGGIASARVFTRIWLALFG
                     WWKWDDLPELPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELH
                     TDASAPNPAKPLAPMASWDGVFQRMDKALHLYHKVAPRGVRKAAMNSAARWIIERQEND
                     GCWGGIQPPAVYSVIALHLMGYDLDHPVLKAGLASLDRFAVWREDGARMIEACQSPVWD
                     TCLAAIALADAGVPADHPQLVKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVAHPDKPRLENAIARGVRWNLGMQSKNGAWAAFDVDNTSSFPNR
                     LPFCDFGEVIDPPSADVTAHVVEMLAYEGKSHDPRTRRGVEWLLAEQEANGAWFGRWGV
                     NYVYGTGSVLPALVAAGLPASHPAIRRAVAWLESVQNDDGGWGEDLRSYRDEQWIGRGA
                     STASQTAWALLALLAAGERDAKCVERGVDWLVQTQTEDGSWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVNGEPALGASGKGG"
     gene            16584..17234
                     /locus_tag="IE274_RS25700"
                     /old_locus_tag="GCM10010349_52750"
     CDS             16584..17234
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639268.1"
                     /locus_tag="IE274_RS25700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52750"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_190118257.1"
                     /transl_table=11
                     /translation="MAVTPAPPGPAPLLVACALGIERLALRTGDRGGASGPMTVLRTGM
                     GPKAAERAVTTALGTPSLRDAAVVATGFCAGLAPGMHPGDLVVAEETRHDGGATPCVGT
                     ELLVEELVRALPRRTVHTGPLTGSDHVVRGHERGDLLATGAIAVDMESAVTLRTAAAAG
                     SRPVAAVRVVVDAPQHELVRIGTVRGGISAFRVLRAVLPAFFEWHRSSLLPRR"
     gene            17240..18262
                     /gene="hpnH"
                     /locus_tag="IE274_RS25705"
                     /old_locus_tag="GCM10010349_52760"
     CDS             17240..18262
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981497.1"
                     /locus_tag="IE274_RS25705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52760"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_030357039.1"
                     /sec_met_domain="PF04055 (E-value: 7.5e-19, bitscore: 62.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2e-10, bitscore: 34.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.4e-06, bitscore: 22.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVMPLRQSIKVATYLMEQKLRKRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKKKYVF
                     LCTNAMLLRKKMDKFTPSPYFAFAVHIDGMRERHDESVAKEGVFDEAVEAMKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDELQVDEMMLSPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRRRWRLNHSPLFLDFLEGKVDFQCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEKTDWSKYGRGKDERCANCMAHCGYEPTAVLATMGSLKESLRAMRETVNGNRG
                     "
     gene            18267..19433
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="IE274_RS25710"
                     /old_locus_tag="GCM10010349_52770"
     CDS             18267..19433
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534474.1"
                     /locus_tag="IE274_RS25710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52770"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_190118258.1"
                     /transl_table=11
                     /translation="MTPGVPVALGLPELPVRPLAERRLSRRIEVGPVAVGGGEPVSVQS
                     MTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALATIARKSQIPVIADIHFQP
                     KYVFAAIDAGCAAVRVNPGNIKQFDDRVRDIARAASDAGTPIRIGVNAGSLDARLLKKY
                     GKATPEALVESALWEASLFEEHGFRDIKISVKHNDPVVMVNAYRQLAAACDYPLHLGVT
                     EAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPAEEVKVGIQILESLNLRQRRLEI
                     VSCPSCGRAQVDVYKLADEVTAGLDGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGK
                     GQIFVKGEVVKTVPESKIVETLIEEAMKIAEQMEAAGVPSGVPDVTVS"
     gene            19457..21427
                     /gene="dxs"
                     /locus_tag="IE274_RS25715"
                     /old_locus_tag="GCM10010349_52780"
     CDS             19457..21427
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642848.1"
                     /locus_tag="IE274_RS25715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52780"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_190118259.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.2e-113,
                     bitscore: 372.8, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.3e-07, bitscore:
                     24.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILETIRGPHDLKALTEADLAELAEEIREFLVHAVARTGGHLGP
                     NLGVVELTMALHRVFESPVDRIVWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SAHDIVENSHASTALGWADGLAKARDVLGERGHVVAVIGDGALTGGMAWEALNNIAAAK
                     DQPLIIVVNDNERSYAPTIGGLANHLATLRTTDSYEQVLAWGKDFLQRTPVVGRTLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHDIKAVESALRRAKRFHGPVLVHCLTEK
                     GRGYEPALADEADRFHTVGVMDPLTCEPLAPSNGPSWTSVFGDEIVRIGAEREDVVAIT
                     AAMLHPVGLTKFAEAYPDRVWDVGIAEQHAAVAAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGPDGASHNGMWDLSVLQVVPGLRIAAPRDADQLRTQL
                     REAVAVDDAPTLLRFPKESVGPVIPAVDRVGVMDVLSRGPEEEEGTAADVLLVAVGVMA
                     PVCLGAADLLRERGISATVVDPRWVKPVDPALPELAGRHRLVAVVEDNSKASGVGAAVA
                     LALGEAEVDVPVRRFGIPDQFLAHAKRGEVLADLGLTPVEIAGSISATIARRDATGAGA
                     PEQAGPTGTKRAGAAGEENRA"
     gene            21424..22818
                     /locus_tag="IE274_RS25720"
                     /old_locus_tag="GCM10010349_52790"
     CDS             21424..22818
                     /NRPS_PKS="Domain: Aminotran_3 (44-366). E-value: 1e-89.
                     Score: 292.8. Matches aSDomain:
                     nrpspksdomains_IE274_RS25720_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642847.1"
                     /locus_tag="IE274_RS25720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52790"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_190118260.1"
                     /sec_met_domain="Aminotran_3 (E-value: 8.7e-89, bitscore:
                     291.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSMSKEFDLGRLLAERGGERYELHARHLNHQLPRMLHTIGFDKV
                     YERAEGAHFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDASLADLTRFDCQPL
                     PGLLAEQLLTHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCAHAFHGLTTGSL
                     SVNGEDGFRDGFAPLLPDTAVPLGDLDALRAELKKGDVAALIVEPIQGKGVHETPPGYL
                     RAAQELLHRHKALLIADEVQTGLGRTGAFYAYEHEDGVEPDLVCVAKALSGGYVPVGAT
                     LGKDWIFKKVYSSMDRVLVHSASFGANAQAMAAGLAVLAVMRDEKVVENARVTGDLLKS
                     RLGALVDRYELLSEVRGRGLMIGIEFGRPKSLKLRSRWTMLQAARKGLFAQMVVVPLLQ
                     KHRILTQVSGDHLEVIKLIPPLTVGEQDVDRFVAAFTAVMDDAHSGGGLMWDFGRTLVK
                     QAVANR"
     aSDomain        21556..22521
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS25720_Aminotran_3.1"
                     /evalue="1.00E-89"
                     /label="IE274_RS25720_Aminotran_3.1"
                     /locus_tag="IE274_RS25720"
                     /protein_end="366"
                     /protein_start="44"
                     /score="292.8"
                     /tool="antismash"
                     /translation="VYERAEGAHFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DASLADLTRFDCQPLPGLLAEQLLTHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCAHAFHGLTTGSLSVNGEDGFRDGFAPLLPDTAVPLGDLDALRAELKKGDVAALIVE
                     PIQGKGVHETPPGYLRAAQELLHRHKALLIADEVQTGLGRTGAFYAYEHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGANAQAMAAGLAVLAVMRDE
                     KVVENARVTGDLLKSRLGALVDRYELLSEVRGRGLMIGIEF"
     gene            22942..23616
                     /locus_tag="IE274_RS25725"
                     /old_locus_tag="GCM10010349_52800"
     CDS             22942..23616
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058825.1"
                     /locus_tag="IE274_RS25725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52800"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_229909804.1"
                     /transl_table=11
                     /translation="MNPAEPAGAAPEPGDAAADPHPDTVADALPVVAPQLRDLRRRAAL
                     TLEAAARAAGLSPAHLSRLETGQRQPSLPMLLALARTYGTTVSELLGETPAERHSVVRA
                     ADMEPTAAGGWTYWQAGAPGRGMQALRVHVPHGAQGDIVRVHPGEEWLYVLTGRLRLRL
                     GDTAYALAPGDSAHFDSLTPHRIAAADHGGADFLFVHTLLQSPATALCLGGPTQGDRHD
                     GT"
     gene            23639..23761
                     /locus_tag="IE274_RS25730"
                     /old_locus_tag="GCM10010349_52810"
     CDS             23639..23761
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642845.1"
                     /locus_tag="IE274_RS25730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52810"
                     /product="DUF6126 family protein"
                     /protein_id="WP_190118415.1"
                     /transl_table=11
                     /translation="MVLEEKFPRALWVRLIIYVAVGHVFAFFVYLLFVLGGQNQ"
     gene            complement(23807..24604)
                     /locus_tag="IE274_RS25735"
                     /old_locus_tag="GCM10010349_52820"
     CDS             complement(23807..24604)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="IE274_RS25735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_52820"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_190118261.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELAGVRNFRDVGGLPTLDGRRVRHGVLFRSGHLAH
                     ATDADAAFLGSLGLHTIFDFRNAADQRLEGPDVALPGVRNVNLPLSDPADGAEFWKMVR
                     DGDLDQLRSILSDGRAAGRMTASYRTIIEERTAEHSRVLHALAEDSVPALMHCAAGKDR
                     AGLSIAVTLLAVGVEREAIHADYLESNAAHRRYKVHRSSTSADAMSPEVMELLSPLFDA
                     RAEYLAAAFETIERTWGDTDTYLERGLGVKPQTRERLRERLLD"
     misc_feature    26545..26558
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
ORIGIN
        1 cggaaagtgg ggacagacgt gtcgccgcgc agggcagcgc cagccacgac agtcatcaac
       61 ccacctcttt cacttccgta aggtcctggc cagggtagca ctgtccgtga tcgggagtcc
      121 cgcccgtgcc tgctcggcct gtacgtgacc aggccgtacg tggccacgcg tccggtcgta
      181 cgtcagtggc acagccccgg ctcgtgctcc gcgtggccgc ccggctccag ctggaacgtg
      241 cagtgctcga cgtcgaagtg gtcgcccagg cagagctgca gctcgtgcag catcttctcg
      301 tggccgatgg cggtcagcgc ctcggagctg acgacgacgt gcgccgagag caccggcatc
      361 cccgacgtga tcgtccaggc gtgcaggtcg tgcacgtcct ccacgccggg cagggccagc
      421 atgtgggcgc ggacctcggc catgtcgacg cccttgggcg ccgattcgag caggacgttc
      481 agggtctccc gcagcagctt ccaggtgcgc gggacgatca tgagcccgat gacgatggag
      541 gcgatggggt cggcggcctg ccagccggtg agcaggatga gggcggccga gacgagcacc
      601 gcgaccgagc ccagcgcgtc cgcgaggacc tccaggaagg cgccgcgcac attgagactg
      661 tccttctggc cgcccatcag cagggccagc gagaccaggt tcgcgagcag gccgatcagg
      721 ccgaagacca tggtcaggcc gccctcggtc gcggcgggcg tgacgaaccg ttgcaccgcc
      781 tcgtacagga cgtacccgcc gacgccgaag agcagcagac agttggcgag cgccgccagg
      841 atctcggcgc gggcgtagcc gaaggtgcgg ttctcgctcg gcgggcggtt cgcgaagtgg
      901 atggcgagca gcgccatgct gaggcccagc gcgtccgtcg ccatgtgcgt cgcatccgcg
      961 atcagcgcga gggagtcggc gacgatgccg ccgacgatct ccaccaccat gacggtgagc
     1021 gtgatggaca gcgcgatgcg caggcgcccc ttgtgggcgg ccgtggccgt gccccgcgcg
     1081 ggcggtgcgt ggccgtggtc gtgtcctgcc cccatggcgc ggtcctccgt cgtcgtcggt
     1141 cgtcgccctg atccggacgc gaccttcagt caactacggg tggggggtat gcgcaacacg
     1201 ctcttgggaa ccgttgtcat atgctctgac ctgcggaaac actccgcagg tcagagcctt
     1261 gaaggtgact ttgcgggacg ctacgactag ccgcgcacgg cctccgggtg gcgcaggcac
     1321 cagcccgccc acgccgactc caccatctcg cgcaccccga gccgggcgct gaagcccagc
     1381 gccttcgcgg ccaggcgtac gtccgccacg gcgcgcggcg cgtcacccgc ccggcgcggt
     1441 tcgaggaggg gctcgcgcgt gtccccggtg acctccgcga tcacggtgag gagttcgcgt
     1501 acggaaacgc cctcgccgcg gccgatgttc accgtcagat cgctgcccgg ctcggcgggc
     1561 ctgcgggcgg cggcgagatg ggcctcggcg aggtcgccga cgtggatgta gtcccgcaca
     1621 caggtgccgt cgggcgtggg gtgatcggtg ccgaagacgc gcggggcctc gccgcgggtg
     1681 aggcggtcga agaccatcgg gaccacgttg aagacaccgg tgtccgccag ctccgggctg
     1741 gcggagcccg ccacgttgaa gtaccgcagg cacgtcgtgg tcagcccgtg ggcccgtccg
     1801 gccgcccgca ccagccactc accggccagc ttcgtctcgc cgtaggggct gaccggcgcg
     1861 cagggcgtgt cctcggcgac caggtcggcg tccggcgggt tgccgtagac ggccgccgac
     1921 gacgagaaga cgaaccgctt caccccggcg tccaccaccg cttcgaggag cgtcgtcagg
     1981 cccccgacgt tctcccggta gtagcgcagc ggctgctcca ccgattcgcc gacctgcttg
     2041 cgggcggcga gatgcacgac ccccgtcacc gcgtgctcgg cgaacacccg ccgcagcagg
     2101 cccccgtcga gcgaagtgcc ccgtaccagt ggaatgtccg acggcagccg ctccggcaca
     2161 cccgaggaga cgtcgtccag gacgaccacc cgctcacccg caccggccat gacccgcgcc
     2221 acatgcgccc cgatatatcc cgctccacct gtgatcatcc atgtcatggg cgtccacctt
     2281 aggctggctt ggtcggttgt ggaccccacg gtttgtggcc gcgggccgct ttcgaccatg
     2341 atgatcgcgg cggtcgagaa ccacgcagac cgcgctgatc ggggcgtgaa cgggcggtga
     2401 acgcccgctt ccattcatcc gatagcctct gccgacatgc cgcccggccg cctcgctgcc
     2461 cgggtgcccc cgtcacgcac gtgcccgcgc gagccgcgcc gggaatcaag gagtgagttc
     2521 gtctgtcgac cgccatcctc accggccggc cggtgcccgg ttcgccgctc gaaggcgatc
     2581 tgcggtccct gggcttcgac gtgcggaccg cccccgaggc ggcgtccccg gaagagctcg
     2641 aggccctgct gcgtgacctg cccgccaccg agcgcgtcgc cctcgtcgac agccgcttcg
     2701 tcggccacgt ccacgccctg cgcctcggcc tgaccgaccc gcgcttcccg gtgtccgccg
     2761 tgcccggcgc catgaccgcg caggcgtcgg cgcgccggga gctgacggcc gcgctgcgca
     2821 cggcagttgg ggccgccggg gctgtcgagg ccgctgccgc cgaggccacc gccgacggcg
     2881 gccgcgcgtc cgtggcggtc gcctccgacg ccgtgcccga ccgcgtcgcc gccgccgtcg
     2941 aggcctccgg caccgacgtg caccggcccg aactcggcac cctcgtcgcg gccctgcccg
     3001 gcgaccccga gtcccgcaac tccgcccgcc aggccgtcgc cgccgtcgac gacgaggccg
     3061 tccgcctgcg cggcgccgtg aaggcccgcg acggcttctt cacgacctac tgcatcagcc
     3121 cgtactcgcg ctacctcgcc cgctggtgcg cccgccgggg cctcaccccg aaccaggtca
     3181 ccaccgcctc cctgctggtg gcggtgatcg cggccggctg cgcggcgacc ggcacccgcg
     3241 gcggcttcgt cgccgccggc gtgctgctcc tgttctcctt cgtcctggac tgcacggacg
     3301 gccagctcgc ccgctactcg ctgcagtact ccacgctcgg cgcctggctc gacgcgacct
     3361 tcgaccgcgc caaggagtac gcgtactacg cgggcctcgc gctcggcgcc gcccgcggcg
     3421 gcgacgatgt gtgggcgctc gcgctcggcg cgatggtcct gcagacctgc cggcacgtcg
     3481 tggacttctc cttcaacgag gcgaaccacg acgccaccgg caacaccagc cccaccgccg
     3541 ccctctccga caagctcgac agcgtcggct ggacggtctg gctgcgccgc atgatcgtgc
     3601 tgcccatcgg cgaacgctgg gccctgatcg ccgtgctcac cgccgtcagc acgccccgca
     3661 tcaccctggt cgtcctgctc atcggctgcg gcctcgccgc ctgctacacc acggcagggc
     3721 gcgtgctgcg ctcgctgacc cgcaaggcga cccgcaccga ccgcgccacg gcggcgctcg
     3781 ccgacctcgc cgacaacggc ccgctcgcgt ccgccttcgc cgcgctgcgg ctgcgcctgc
     3841 cgctgcccgc gcccgccgtc gccttcgccg gcggcgccgc ggtggtctgc gcggccctct
     3901 tcagctccta cggcagcccg tgggtggtgg tcggcgccgt ggtgtacgtc atcgcgtccg
     3961 gactcgccct cggccgcccc ctcaagggcg ccctcgactg gctggtgccg ccgttcttcc
     4021 gggtcgcgga gtacggcacc gtactggtgc tggcggccaa agccgatgtg aacggaagcc
     4081 ttcccgcggc tttcggcctg gtggccgcgg tcgcctacca tcactacgac acggtgtacc
     4141 gcatcaaggg cggcaccggc gcgcccccgc gctggctggt gcgggcgatc ggcggccaag
     4201 agggcaggac cctggcggtc gcgctggccg ccttcgcact gcacgacaca gatttcaccg
     4261 tcgcgctcac ggctctcgcc gtggccgtgg cactcgtggt gctcatcgag agcatccgct
     4321 tctgggtgac cgctcacatg cgtggcgcac ccgccgtaca cgatgaagga gaacccgcat
     4381 gatcggcctc gtcctggctg ccggcgccgg ccggcgcctg cgtccctaca ccgaaacgct
     4441 gcccaaggcg ctggtgcccg tcgtgggcga gggaaccgag aatgagctgg ccgtcctcga
     4501 cctcaccctg aagaacttcg ccgagatcgg cctgaccgag gtcgcgatca tcgtcggcta
     4561 caagaaggaa gccgtctacg accgcaaggc ggccctggag gcgaagtacg gcctcaagct
     4621 gacgctcatc gacaacgaca aggccgagga gtggaacaac gcctactccc tgtggtgcgg
     4681 ccgtgacgcc atcaagcacg acgtgatcct cgccaacggc gacaccgtgc acccggtctc
     4741 cgtcgagaag acgctgctcg ccgcccgcgg cgacggcaag aagatcatcc tggccctcga
     4801 cacggtgaag cagctcgccg acgaggagat gaaggtcgtc gtggaccccg agaagggcgt
     4861 ccagaagatc accaagctga tggacccggc cgaggccacc ggtgagtaca tcggcgtcac
     4921 cctcatcgag ggctccgccg ccgacgagct cgccgacgcc ctgaagacca ccttcgagcg
     4981 cgaccccgac ctctactacg aggacggcta ccaggagctc gtcaaccgcg gcttcaaggt
     5041 cgacgtggcg ccgatcggcg acgtcacgtg ggtcgagatc gacaaccacg acgacctcgc
     5101 caaggggcgt gaaatcgcgt gccagtactg acgaggctca tcccctcgcc ggtcgtcgtc
     5161 gacatccggg caggggcgtt gaacgacctg gccggtgtcc tcgccgacca gcggatctgc
     5221 tcgtcgaccg gcaagctcgc catcgccatc agcggcggct ccggcgcggt gctgcgcaag
     5281 cggctcgcgc cgtcgctgcc gagcgctgaa tggttcgagg tgggcggcgg caccctcgat
     5341 gacgccatca agctcgccga ggccatgaag aagggccgct acgacgcggt cgtcggcctc
     5401 ggcggcggca agatcatcga ctgcgccaag ttcgccgcgg cgcgcgtcgg tctgccgctg
     5461 gtcgccgtcg cgacgaacct gtcgcacgac ggtctgtgct cgcccgtcgc gacgctcgac
     5521 aacgacgcgg gccgcggctc ctacggcgtg ccgaacccga tcgcggtcgt catcgacctc
     5581 gacgtcatcc gcgaggcccc ggtccgcttc gtgcgctccg gcatcggcga cgccctgtcc
     5641 aacatctccg cgatccggga ctgggagctg gccgcccgcg agcgcggcga ggacatcgac
     5701 ggcctggccg ccgcgatggc ccgccaggcc ggcgaggcgg tcctgcgcca ccccggcggc
     5761 gtcggcgacg acggcttcct gcaggtactc gccgagggcc tggtcctcac cggcatcgcc
     5821 atgtccgtct cgggcgactc ccgcccggcg tccggcgcct gccacgagat caaccacgcc
     5881 ttcgacctgc tcttccccaa gcgcgccgcg agccacggcg agcagtgcgg cctcggcgcc
     5941 gccttcgcga tgtacctgcg cggtgcccgc gaggagtcgg cgtacatggc ggaggtcctg
     6001 cgccgccacg gcctgccggt cctgcccgag gagatcggct tcaccgtgga cgagttcgtc
     6061 caggtcgtcg agtacgcgcc gcagacccgg ccgggccgct acacgatcct cgagcacctc
     6121 aatctgaaca ccgaccagat caaggacgca tacgccgact atgccaaggc catcggtagc
     6181 tgaactccgg cccgtcgttc accccgcggg ggtgaaggac cggcgcagcg gtgagcactg
     6241 ggcgggacgc atgtacatgc gggagatctc gctgcgctgc gaccgctacc tggtgaacac
     6301 caggatcacg cccaatcagc tgacctacct gatgaccgtc gcgggcgtcc tcgccgcccc
     6361 ggccctcctg gtgccgggga tctggggcgc ggtgctcggc gtcgtcgcgg tccagctcta
     6421 tctgctgctc gactgcgtcg acggcgagat cgcccgctgg cgcaagcagt actcgatgtc
     6481 cggggtgtac ctggaccggg tcggcgccta tctgtgcgac gcggcggtgc tggtcggctt
     6541 cggcctgcgc gccgccgacc tgtggggctc gggccgcatc gactggctgt gggccttcct
     6601 cggcaccctg gccgccctcg gcgccatcct gatcaaggcc gagaccgacc tcgtcgcggt
     6661 cgcccgccat cagcagggca tggctcccgt ccaggagtcg gcggccgagc cgcgcgccgc
     6721 cggcatggcc ctggcacgca aggccgcggc cgcgctgaag ttccaccggc tgatcctcgg
     6781 catcgaggcg tcgctgctga tcctggtcct cgcgatcgtg gactcggtca ggggagacct
     6841 gttcttctcc cgtgtcgggg tcgccgtgct cgcgggcatc gcgctcctgc agaccctgct
     6901 gcacctcgtg tccatcctcg tgtcgagcag gctgaagtga gtacaccgag ccccgccggt
     6961 acaccgggga cgtcgaccgc gccgctcaag gtcggcgcgg tcgtcatcac catgggcaac
     7021 cgcccccagg agctgcgcgc cctgctcgac tcggtcgcca agcaggacgg cgaccgggtc
     7081 gaggtggtcg tcgtcggcaa cggcgccccc gtgccggacg tgcccgcggg cgtgcgcacc
     7141 atagaactgc ccgagaacct gggcatcccg ggcgggcgca acgtgggcat cgaggccttc
     7201 ggcccgggcg gcaccgacgt cgacatcctg ctgttcctcg acgacgacgg gctgctcgcg
     7261 cacaccgaca ccgccgagct gtgccgcgcg gccttcgcgg cggaccccga gctcggcatc
     7321 atcagcttcc gcatcgccga cccggacacc ggcatcaccc agcgccgcca cgtgccgcgc
     7381 ctgcgcgcct cggacccgat gcgctcctcg cgcgtgacga cgttcctcgg cggcgccaac
     7441 gccgtgcgca ccgaggtcct gaaggaggtc ggcggcctgc cggacgcctt cttctacgcc
     7501 cacgaggaga cggacctcgc ctggcgcgcc ctggacgcgg gctggatgat cgactaccgc
     7561 gcggacatgg tgctcttcca ccccaccacg gccccctccc ggcacgcggt ctaccaccgc
     7621 atggtggccc gcaaccgcgt ctggctggcc cgccgcaacc tgcccgccct cctggtgccc
     7681 gtgtacctcg gcgtctggct cctgctgacc ctcgcccggc gcccctcgcg gcccgccctg
     7741 aaggcctggt tcggcggttt caaggagggc tggaccagcc cgagcggacc tcgccgcccc
     7801 atgaagtggc gtacggtgtg gcgcctgacc cggctgggcc gacctcctgt gatctgacaa
     7861 gctcgggtct gagaacattc gggccgtatt ccggtccctg gccccccagg cctacgcccg
     7921 accggccgtg catctgaaga cgaaagtttc ccctcgtgag tgagacaacg caggacggtg
     7981 gagtcgcggt gaccgcgcca ccgtcgcccg acgacgggct gtcccccgca gagctggcgg
     8041 ccaagtacgg cctgtccgtc agcggcgccc gtccgggtct tttcgagtac gtcagccagc
     8101 tctgggggcg gcgccacttc atcctcgcct tctcacaggc gaagctcacc gcccagtaca
     8161 gccaggccaa gctcggccag ctctggcagg tggcgacacc gctgctcaac gcgctcgtct
     8221 acttcctcat cttcggcctg atcctcaagg ccgaccgggg catgtcccgg gaggtgtaca
     8281 tcccgttcct cgtgacaggc gtcttcgtct tcaccttcac gcagagctcg gtgatggcgg
     8341 gcgtacgggc gatctcgggc aacctcggcc tggtgcgcgc gctgcacttc ccgcgcgcct
     8401 cgctgcccgt ctccttctcg ctgcagcagc tccagcagct gctgttctcg atgatcgtgc
     8461 tgttcgtggt ggcggtcggc ttcggcagct atccgaagct gtcctggctg ttgatcctgc
     8521 cggtgctcgc gctgcagttc ctcttcaaca ccgggctcgc gctggtcatg gcgcggctcg
     8581 gcagcaagac ccccgacctc gcgcagctga tgccgttcgt gatgcgcacc tggatgtacg
     8641 cgtccggcgt gatgttctcc atcccggtga tgctcaagga gcacccggcg tggatcggcg
     8701 acatcctcca gtggaacccg gccgccatct acatggacct gatgcgcttc gcgctcatcg
     8761 acggctacgg ctccgagaac ctgccgccgc acgtctgggc ggtcgcggcc ggctgggccg
     8821 tgctcgtcgc cgtgggcggc ttcgtgtact tctggaaggc ggaggagcgg tacggccgtg
     8881 gctgacgaca agagcgccga ccgggcgcac atccccaccg tcatcgcgga cgagctgcac
     8941 atcgtctacc gcgtcaacgg cgccaagacg ggcaagggca gcgccacctc cgcgctgagc
     9001 cgcatcatca agcgcggcga ggagcgcggc gtgcgcaagg tgcacgccgt ccgcggggtc
     9061 agcttcaccg cctaccgcgg cgaggcgatc ggcctcatcg ggtccaacgg ctccggcaag
     9121 tccaccctgc tgcgggccat cgcgggcctg ctcccggccg agaagggcaa ggtctacacc
     9181 gacggccagc cctcgctcct cggggtgaac gcggccctca tgaacgatct gaccggcgag
     9241 cgcaacgtca tcctcggcgg gctcgcgatg ggcatgagcc gtgagcagat cagggagcgc
     9301 taccaggaca tcgtcgactt ctccggcatc aacgagaagg gcgacttcat caccctgccg
     9361 atgcgcacct actcctccgg catggccgcc cgcctgcggt tctccatcgc ggcggccaag
     9421 gaccacgacg tgctgatgat cgacgaggcg ctggccaccg gcgaccgcaa gttccagaag
     9481 cgctccgagg cccgcatccg cgagctgcgc aaggaagcgg gctcggtctt cctggtcagc
     9541 cacaacaaca agtcgatccg tgacacctgc gaccgcgtgc tctggctgga gcggggcgag
     9601 ctgcggatgg acggaccgac cgacgaggtc atcaaggagt acgagaagtt caccggcaag
     9661 tagccgaatg gccgcacgcg cgcggcggcc gaacgggtca gggctccgcc gggacactcc
     9721 ggcggggccc tgacccgttc ttcggacatc aggagtccct caagtcaccg gagttcaggg
     9781 aagattggag ccaatcggtg cgttgttgtg atgtgccgaa caccccgacg actcggtgtg
     9841 cgttgtacaa cgtaagctgt accggtgctg attcgcggca agtggggcga tatcgcgcgg
     9901 catcggggtg gcgggcgcgg tcggccgcac ggggggcagg gcggcgtgtc cgaaatagga
     9961 tgttttgggt cggcagtgta gaacgggaga tgtgacggca atggctacgg acgatctccg
    10021 gctccgcgat gcgtccgccg tcctcgacaa agccgcggac gagaactttc ccgtggcccc
    10081 gttcttcctc ccgcgcgcct ggcgcgagga cctcatggcc gtgtacggct acgcccgcct
    10141 ggtcgacgac atcggcgaca ccgacctcga ccgcggcgcc gcccacgccc gctacctcgg
    10201 cgcggacccc gaggccgccg gtgacccgct cgccctcctc gacgccttcg aagccgacct
    10261 gaacaaggtc ttcgcaggtc aggaccccgg ccacccgcta ctgcaggccc tggtgcccac
    10321 cgtgcgccgc cggggcctga cccccgagcc gttcctcggc ctgatcgcgg ccaaccgcca
    10381 ggaccagctc gtcaagcggt acgagaccta cgacgacctg ctcgcctact gcgagctgtc
    10441 cgcgaacccc gtcggccgcc tggtcctcgc catcaccggc accgcgaccc ccgagcgcat
    10501 ccgcctctcc gactcggtgt gcacggcgct gcagatcgtg gagcacctcc aggacgtacg
    10561 cgaggacctg ggccgcgatc gggtctacct gcccgccgag gacatgaagc ggtttcatgt
    10621 ccaggagcgg gacctggctg tccctacggc aggcgcatcg gtgcgcgcac tggttgcata
    10681 tgaagcggaa cgcgcccatg gcctcctgaa tgaaggcacc cccctggtgg gtagcgtcca
    10741 cggcaggctg aagctgctgc ttgcagggtt cgtggcaggg ggaagggcgg cgatcgcggc
    10801 gatcgccgcc gccggatacg acgtacttcc aaggccgccg aagcccacga aaccgcgcct
    10861 ggtgcgcgag gtgggcgcgg ttctgcgagg agaggggtga gccggaccgt ggagtcagaa
    10921 cctcgcgtgt ccgcgccggt actcgccgca tacagctatt gcgagaccgt gaccgggcag
    10981 caggcacgca atttcgcgta cggcatcagg ttgctgccga cgcccaagcg gcgggcgatg
    11041 tccgcgctct acgcgttctc ccggcgcgtg gacgacatcg gcgacggcac cctcgcgccg
    11101 gacgtgaagg gggcgcggct cgacgacacc cgggcgctgc tcacccgcgt ccgcgacggc
    11161 gaggtggagg aggacgacac cgaccccgtg gccgtggcgc tcagccacgc ggcccagcac
    11221 ttcccgatcc cgctcggcgg gctcgacgag ttgatcgacg gcgtcgtgat ggacgtgcgc
    11281 ggcgagacgt acgagacctg ggaggacctg aaggtctact gccgctgtgt ggccggtgcc
    11341 atcggacggc tctcgctcgg ggtcttcggc accgagccgg gggcgctgca cgcggagcgc
    11401 gcgccggagt acgccgacac gctcggcctc gcactccaac tcaccaacat cctccgggac
    11461 gttcgcgagg acgccctgga gggacgcacc tacctgccgg ccgacgacct cgccaagttc
    11521 ggctgctctg ccgggttctc ccgccccgag ccgcccgccg ggtcggactt cgcgggcctc
    11581 gtccacttcg aagtccgccg tgcccgcgcc ctgttcgccg agggctaccg gctgctgccg
    11641 atgctggacc ggcgcagcgg tgcctgtgtg gcggcgatgg cgggcatcta ccgccgcctg
    11701 ctggatcgca tcgagcggga accggaagcg gtgctccggg gccgcgtttc gctgccggga
    11761 cgcgagaagg cgtatgtcgc cgtgcgcggt ctgtccgggt tcgacgcgcg cagcgtctcc
    11821 cggggggccg tcaggaggcg tacgtgatgc gcaggtacgg cggcgccggt gcaggtcctg
    11881 tgcgtcgccg caaacggcgg gcaaccctcc gcatgaccat ggcgtcccag actgcaactg
    11941 ccgaaaggga ggacgcatga ggcaggacga caggcagccc gaagggggcg ccgacggagc
    12001 cggtaaacgg gcgtccgccg tcgtcgtggg cggcggcctg gccggtatca cctccgccct
    12061 cgccctggcc gacgccggcc tcgacgtcac tctgctcgag ggccgcccgc gcctcggcgg
    12121 actcgccttc tccttccagc gcggcgaact gaccgtcgac aacggccagc acgtctacct
    12181 gcgctgctgc accgcctacc gctggttcct cgaccgggtc gagggcgcgc acctggcgcc
    12241 ggtgcaggac cgtctcgacg tacccgtgct cgatgccgac cggaaccggc tcggacgcct
    12301 gcgccgcacc gcgctgccgg tgccgctgca cctggccgcg agcctcgccg gctacccgca
    12361 tctgtcgctc gccgagcgcg ctgccgtggg gcgcgcggcg ctcgccctca agggactcga
    12421 cccggccgac ccggcgctcg acagtcagga cttcggcagc tggctggccg cccgcggaca
    12481 gtcgaagcgc gccatcgagg ccctgtggga cctcgtcggg gtcgccaccc tcaacgccgt
    12541 cgcgggcgat gcctcgctgg gcctcgccgc gatggtgttc aagaccgggc tgctctccga
    12601 gccgggcgcc gccgacatcg gctgggcgcg ggtgcccctc ggtgacatcc atgacggtct
    12661 ggcccgcaag gcgctcgact cggcgggcgt gcgtaccgaa ctaagagcac gtgtcacctc
    12721 cgtctcccgt agtaagaacg gtggttggcg cgtcgaggtt cccggcgagt ccattccggc
    12781 cgacaccgtg gtgctcgccg tgccccaggc cgagacccac gatctgctcc cggacggtgc
    12841 cctcgacgag cccgaccggc tgctcggcat cgacaccgcg ccgatcctga acatccatgt
    12901 cgtgtacgac cgcaaggtcc tgagaaggcc cttcttcgcc gcgctcggca cccccgtgca
    12961 gtgggtcttc gaccggaccg aggcctcggg cctggcccag gggcagtatc tggcgctgtc
    13021 gcagtcggcc gcccaggacg agatcgacgc tcccgtggcg gcgctcaggg agcgctatct
    13081 gccggagctc gagcgcctcc tgcccgccgc gcacggcgca cgggtcctcg acttcttcgt
    13141 gacccgggag cgcacggcga cattcgcgcc cacgccgggc gtcggccgcc tgcggccggg
    13201 cgcgcacacc aacgcgtccg ggctctacct ggccggcgcg tggaccgcga ccggctggcc
    13261 cgcgacgatg gaaggcgctg tgcgcagcgg catcaccgca gccagggcgg ccctgaccgc
    13321 actggaccgc ccccatggcc atctcttcga ggaggcggcg tgaagctcga cctgctgggg
    13381 cccccgcccc acgaaccccg caccggaacc agaggagaga atgtgccgac tgtgccctcg
    13441 gccgaaccgg ccgctgtgga cgtgaccgcg ctgctggaac gcggccggac gctggccacc
    13501 ccggtcctgc ggtccgcggt ggaccgcctc gcgccgccca tggacaccgt cgccgcctac
    13561 cacttcggct ggatcgacgc ggccggcaac ccggccgtcg gcgacggcgg caaggccgtg
    13621 cgcccggcgc tcgccctgct ctccgcggag gccgcgggcg cgagcccgga gaccggcgtg
    13681 cccggcgcgg tcgccgtcga gctggtccac aacttctcgc tcctgcacga cgacctgatg
    13741 gacggcgacg agcagcgccg ccaccgcgac acggtgtgga aggtgcacgg ccccgcgcag
    13801 gcgatcctcg tcggcgacgc gctgttcgcc ctcgccaacg agatcctgct cgaactcggc
    13861 accgtcgagg cgggccgcgc gacccgccgc ctgaccaccg cgacccgcgc cctcatcgac
    13921 ggccaggcgc aggacatctc ctacgagcac cgcgagcggg tcaccgtcga ggagtgcctg
    13981 gagatggagg gcaacaagac gggcgcgctg ctcgcctgcg cggtctccat cggcgcggtc
    14041 ctcggcggcg ccgacgacgc caccgccgac atcctggaga agtacggcta ccacctgggc
    14101 ctcgccttcc aggccgtcga cgacctgctc ggcatctggg gcgaccccga ggccaccggc
    14161 aagcagacgt ggagcgatct gcgccagcgc aagaagtcgc tgccggtggt cgccgcgctc
    14221 gccgcgggcg gcccggcctc ggagcggctc ggcgagctgc tcgccgccga cgccaagagc
    14281 aacgacttcg acagcttctc cgaggaggag ttcgccgcgc gcgccgccct gatcgagcag
    14341 gcgggcggcc gcgagtggac cgccgaggag gcgcgacggc agcacgccgt cgccatcgag
    14401 gccctggacg cggtccagat gccggaccag gtgcgggcgc agctcaccgc gctcgccgac
    14461 ttcgtcgtcg tacgaaagag atgatcacta tcggccccaa ctgaatcgca gtcgccggcc
    14521 tgtgtccctc cagggcaccg gccgacggcg gacccagcag agatgaagca ctgcgtagaa
    14581 ggggaagcca tgacagcgac gaccgacgga agcaccggag cggcaacgcc ccgagcggcc
    14641 tcggccaccg gaacgaccga caccaccccc gcgccgcccg gggtgccggg tgccgcggcg
    14701 cgcgccatag aacggtccac tcaattcctg ttgtcccgcc aggacgccca gggatggtgg
    14761 aagggcgacc tggcaaccaa tgtgaccatg gacgccgagg acctgttgct ccgtcagttc
    14821 ttgggcatcc aggacgaatc gacgaccagg gccgccggac tcttcatccg cggcgagcag
    14881 cgtgacgacg gcacctgggc caccttctac ggcggccccg gcgaactctc cgccaccatc
    14941 gaggcgtatg tcgcgctgcg cctcgcgggg gacgcacccg acgccccgca catggcgaag
    15001 gcgtccgcct ggatcaggga gcgcggcggc atcgcctccg cccgggtctt cacccgcatc
    15061 tggctcgccc tcttcggctg gtggaagtgg gacgacctgc ccgagctgcc gcccgaactc
    15121 ctttattttc ccaagtggtt cccgctcaac atttacgatt tcggctgctg ggcgcgacag
    15181 accatcgtgc cgctcaccat tgtctcggcc aagcgtccgg tccgtcccgc gcccttcgcg
    15241 ctggacgagc tgcacaccga cgcgagcgcg ccaaaccccg ccaagcccct tgccccgatg
    15301 gcgagttggg acggcgtctt ccagcgcatg gacaaggcgc tgcaccttta tcacaaggtc
    15361 gcgccgcgcg gcgtgcgcaa ggcggcgatg aacagcgccg cgcgctggat catcgaacgg
    15421 caggagaacg acggctgctg gggcggcatc cagccgcccg ccgtgtactc cgtgatcgcg
    15481 ctgcacctga tgggctacga cctcgaccac ccggtcctga aggccggtct cgcgtccctg
    15541 gaccggttcg ccgtgtggcg cgaggacggt gcccggatga tcgaggcctg tcagtcgccg
    15601 gtgtgggaca cctgcctggc ggccatcgcc ctcgccgacg ccggggtgcc cgccgaccat
    15661 ccgcagctcg tcaaggccgc ggactggatg ctgggcgagc agatcgtgcg gcccggcgac
    15721 tggtcggtgc gcaggccggg cctcaccccc ggcggctggg ccttcgaatt ccacaacgac
    15781 aactaccccg acatcgacga caccgccgag gtcgtcctcg cgctgcgccg ggtcgcgcac
    15841 ccggacaagc cgcgcctgga gaacgccatc gcgcgcgggg tgcgctggaa cctcggcatg
    15901 cagtcgaaga acggcgcctg ggccgccttc gacgtcgaca acaccagttc cttccccaac
    15961 cggttgccgt tctgcgactt cggcgaggtc atcgacccgc cctccgccga cgtcaccgcg
    16021 cacgtcgtgg agatgctcgc ctacgagggc aagtcccacg acccgcgcac ccggcgcggc
    16081 gtggagtggc tgctcgccga acaggaggcg aacggcgcct ggttcgggcg ctggggcgtc
    16141 aactacgtct acggcaccgg gtcggtgctg cccgcgctcg tcgccgccgg gctgcccgcc
    16201 tcgcatccgg cgatccggcg cgcggtcgcc tggctggagt cggtgcagaa cgacgacggc
    16261 ggctggggcg aggacctgcg ctcctaccgc gacgagcagt ggatcggacg cggcgcctcc
    16321 accgcgtccc agacggcctg ggcgctgctg gcgctgctcg cggccgggga gcgggacgcc
    16381 aagtgcgtgg agcgcggtgt cgactggctg gtccagacgc agaccgagga cggctcctgg
    16441 gacgagccgt acttcaccgg caccggcttc ccctgggact tctccatcaa ctaccacctc
    16501 taccggcagg tcttcccgct gaccgcgctc ggccggtacg tcaacggaga gccggccctc
    16561 ggtgcctccg gcaagggggg ctgatggccg tgaccccggc gccgccgggc cccgcaccgc
    16621 tcctcgtcgc ctgtgcgctc ggcatcgagc gcctcgccct gcgcaccggc gaccggggcg
    16681 gcgcgagcgg gcccatgacc gtcctgcgga ccggcatggg cccgaaggcc gccgagcgcg
    16741 ccgtcaccac ggcgctcggc accccgtccc tgcgggacgc ggcggtcgtg gccaccggct
    16801 tctgcgccgg gctcgccccc ggcatgcacc ccggcgacct ggtcgtcgcc gaggagaccc
    16861 ggcacgacgg cggcgccacg ccctgcgtcg gcacggaact cctggtcgag gagctggtgc
    16921 gggcgctgcc ccggcgcacc gtgcacaccg ggccgctcac ggggtccgac cacgtcgtcc
    16981 gcggccacga acgcggcgat ctgctcgcca ccggcgcgat cgcggtggac atggagtccg
    17041 ccgtcacgct gcgcaccgcg gcggcggccg ggtcccggcc ggttgccgcc gtccgggtgg
    17101 tcgtggacgc cccacagcac gaactcgtac ggatcggcac ggtgcgcggt ggaatatcgg
    17161 ccttccgcgt tctccgtgcc gtgcttcccg ctttcttcga atggcaccgt tcttcgctgc
    17221 tcccccggag gtgagccaga tggtcatgcc gctgcgtcag tcgatcaagg tcgctacgta
    17281 cctgatggaa cagaagctgc gcaagcggga caagttcccg ctgattgtcg agttggagcc
    17341 gctgttcgcc tgcaatttga agtgcgaggg ctgcggcaag atccagcacc cggccggggt
    17401 gctcaagcag cggatgccgg tggcccaggc cgtgggcgcc gttctcgagt ccggtgcgcc
    17461 gatggtgtcc atcgccggtg gcgagccgct gatgcaccct cagatcgatg agatcgtaag
    17521 gcagttggtc gccaagaaga agtacgtctt cctttgcacc aatgccatgc tgctgcgcaa
    17581 gaagatggac aagttcacgc cctcgccgta tttcgcgttc gccgtgcaca tcgacgggat
    17641 gcgggagcgc cacgacgagt cggtggcgaa ggagggggtg ttcgacgagg cggtcgaggc
    17701 catgaaggag gccaagcggc gcggcttccg ggtcaccacc aactcgacct tcttcaacac
    17761 cgacaccccg cagacgatca tcgaggtgct caacttcctc aatgacgagc tgcaggtcga
    17821 cgagatgatg ctgtcgcccg cctacgccta cgagaaggcg cccgaccagg agcacttcct
    17881 cggcgtcgag cagacccgcg agctgttcaa gaaggccttc gcgggcggca accggcggcg
    17941 ctggcggctc aaccactcgc cgttgttcct cgacttcctc gagggcaagg tcgatttcca
    18001 gtgcacggcg tgggcgatcc ccaactactc gctcttcggc tggcagcgcc cctgctatct
    18061 gatgagcgac gggtacgtcc cgacgtaccg ggagctgatc gagaagaccg actggtccaa
    18121 gtacggccgc ggcaaggacg agcggtgcgc caactgcatg gcgcactgcg gctacgagcc
    18181 cacggccgtg ctcgccacca tgggctccct caaggagtcc ctgcgggcca tgcgcgagac
    18241 cgtcaacgga aatcgcgggt gacgtcatga cccctggagt gcccgtcgca ttgggcctcc
    18301 cggagctgcc ggtccggccc ctcgccgagc gccgcctctc gcggcgcatc gaggtcggac
    18361 cggtggccgt ggggggcggc gagccggtgt cggtgcagtc gatgacgacg acgcgtacgt
    18421 cggacatcgg ggcgacgctg cagcagatcg cggagctgac ggcgtcgggg tgccagatcg
    18481 tccgggtggc gtgtccgacg caggacgacg ccgacgcgct cgcgacgatc gcgcgcaaat
    18541 cgcagatccc ggtgatcgcc gacattcact tccagccgaa gtacgtgttc gcggcgatcg
    18601 acgccgggtg cgcggcggtg cgggtgaacc ccggcaacat caagcagttc gacgaccggg
    18661 tgcgggacat cgcccgggcg gcgagcgacg cgggtacgcc gatccgcatc ggcgtcaacg
    18721 cgggttccct ggacgcgcgc ctcctgaaga agtacggcaa ggcgacgccc gaggcgctgg
    18781 tcgagtcggc gctgtgggag gcgtccctct tcgaggagca cggcttccgg gacatcaaga
    18841 tctcggtgaa gcacaacgac ccggtggtga tggtcaacgc ctatcggcag ttggccgccg
    18901 cctgcgacta tccgctgcac ctgggtgtga cggaggccgg tccggcgttc caggggacga
    18961 tcaagtcggc cgtcgcgttc ggcgcgctgc tcagcgaggg catcggcgac acgatccgcg
    19021 tctcgctgtc ggctcctccg gccgaggagg tcaaggtcgg catccagatc ctggagtcgc
    19081 tgaacctgcg ccagcggcgc ctggagatcg tgtcgtgccc ctcctgcggg cgcgcccagg
    19141 tcgacgtgta caagctggcg gacgaggtga cggcggggct cgacggcatg gaggtgccgt
    19201 tgcgggtcgc ggtcatgggg tgtgtggtga acgggccggg tgaggcgcgt gaggccgatc
    19261 tgggtgtcgc gtccggcaac ggcaaggggc agatcttcgt gaagggcgag gtcgtcaaga
    19321 ccgtgcccga atcgaagatc gtggagaccc tgatcgaaga ggcgatgaag atcgccgagc
    19381 agatggaggc cgcaggcgtc ccgtccgggg tgcccgacgt caccgtgagc tgaacaacca
    19441 gtaagggggc ccgagcatga ccattctgga gacgatccgg gggccgcacg acctgaaggc
    19501 gctgaccgaa gccgatcttg ccgaactggc ggaggaaata cgggagttcc tggtgcacgc
    19561 ggtcgccagg accggcggtc acctcgggcc caacctgggc gtggtggagc tcaccatggc
    19621 cctgcaccgg gtcttcgagt cgcccgtcga ccgcatcgtg tgggacaccg gccaccagag
    19681 ctacgtgcac aagctgctga ccgggcgtca ggacttctcc aagctgcgcg gcaaaggggg
    19741 cctgtccggc tatccctcgc gcgaggagtc cgcacacgac atcgtcgaga acagccacgc
    19801 gtcgaccgcg ctcggctggg ccgacggcct cgccaaggcc cgtgacgtgc tcggcgagcg
    19861 cgggcacgtc gtcgccgtca tcggggacgg cgcgctcacc ggcggcatgg cctgggaggc
    19921 gctgaacaac atcgcggccg ccaaggacca gccgctgatc atcgtcgtca acgacaacga
    19981 acgctcgtac gcccccacca tcggcggcct cgccaaccac ctggccaccc tgcgcaccac
    20041 cgacagctac gagcaggtcc tcgcctgggg caaggacttc ctccagcgca cccccgtcgt
    20101 cggccgcacc ctgtacgaat cgctgcacgg cgctaagaag ggcttcaagg acgccttcgc
    20161 accgcagggc atgttcgagg acctgggcct gaagtacgtc ggcccgatcg acgggcacga
    20221 catcaaggcc gtcgagtcgg cgctgcgccg cgcgaagcgc ttccacgggc ccgtgctcgt
    20281 gcactgcctc accgagaagg gccgcggcta cgaacccgcg ctcgccgacg aggccgaccg
    20341 cttccacacc gtcggcgtca tggaccccct cacctgtgag cccctcgccc cgtccaacgg
    20401 cccttcctgg acctcggtgt tcggcgacga gatcgtccgc atcggcgccg agcgcgagga
    20461 cgtcgtggcg atcacggccg ccatgctgca cccggtgggc ctcaccaagt tcgccgaggc
    20521 ctatcccgac cgggtgtggg acgtcggcat cgccgagcag cacgcggcgg tcgcggccgc
    20581 cgggctcgcc accggcgggc tccaccccgt cgtcgccgtc tacgccacct tcctcaaccg
    20641 cgccttcgac cagctcctga tggacgtcgc gctgcaccgg tgcggggtca ccttcgtgct
    20701 cgaccgcgcc ggggtcaccg ggcccgacgg cgcctcgcac aacggcatgt gggacctgtc
    20761 cgtcctccag gtcgtccccg gcctgcgcat cgccgcgccg cgcgacgccg accagctccg
    20821 gacacagttg cgcgaggccg tcgccgtcga cgacgcgccc acgctgttgc ggttccccaa
    20881 ggagtcggtg gggcccgtga tcccggccgt ggaccgcgtc ggcgtcatgg acgtgctgag
    20941 ccggggcccc gaagaggagg aggggacggc cgccgatgtg ctgctcgtcg cggtcggcgt
    21001 gatggccccg gtgtgcctgg gcgccgccga tctgctgcgg gagcggggga tcagtgccac
    21061 cgtggtcgac ccgcgctggg tcaagcccgt ggacccggcg ctgcccgagc tcgcggggcg
    21121 gcaccggctc gtcgcggtcg tcgaggacaa cagcaaggcg tccggggtcg gcgcggcggt
    21181 cgcgctggcc ctgggcgagg ccgaagtgga cgttcccgta cggcggttcg gcatccccga
    21241 ccagttcctc gcgcacgcca agcggggcga ggtcctcgcc gacctcgggc tcacccccgt
    21301 cgagatcgcc gggagcatca gcgcgaccat cgcgcgccgg gacgccaccg gcgccggcgc
    21361 gccggaacag gccggtccca ccggcaccaa gagagccggt gcggccggcg aggagaaccg
    21421 ggcatgacca gcatgagcaa ggagttcgac ctcggccgac tgctcgccga gcgcggcggc
    21481 gaacggtacg aactgcacgc gcgccacctg aaccaccagt tgccgcggat gctccacacc
    21541 atcggcttcg acaaggtcta cgaacgcgcg gagggcgccc acttctggga cgcggacggc
    21601 aacgactacc tggacatgct cgccgggttc ggcgtcatgg gactcggccg ccaccacccc
    21661 gtcgtacgca aggcgctgca cgacgtcctc gacgcctccc tcgccgacct cacccgcttc
    21721 gactgccagc ccctgcccgg cctgctcgcc gagcaactgc tcacccacag cccgcacttg
    21781 gaccgggtgt tcttcggcaa cagcggcacc gaggcggtgg agacggccct gaagttcgcg
    21841 cggtacgcca ccggcaagcc gcgcgtcctg tactgcgcgc acgccttcca cggcctgacc
    21901 accggctccc tgtcggtcaa cggcgaggac ggcttccggg acggcttcgc gccgctgctt
    21961 ccggacacgg cggtgccgct cggcgatctg gacgcgctgc gcgccgagtt gaagaagggc
    22021 gacgtcgccg cgttgatcgt cgagcccatc cagggcaagg gcgtgcacga gacgcccccc
    22081 ggctatctgc gcgccgccca ggaactgctg caccggcaca aggcactcct catcgccgac
    22141 gaggtgcaga ccgggctcgg ccggaccggc gcgttctacg cgtacgagca cgaggacggc
    22201 gtcgaacccg acctggtgtg cgtggccaag gcgctgtccg gcggctatgt gccggtcggc
    22261 gccaccctcg gcaaggactg gatcttcaag aaggtctact cgtccatgga ccgcgtcctg
    22321 gtccactcgg cgagtttcgg ggcgaacgcg caggccatgg cggccgggct cgccgtcctc
    22381 gccgtcatgc gggacgagaa ggtggtcgag aacgcgcgcg tgaccggcga cctcctgaag
    22441 tcacggctcg gcgcgctcgt cgaccgctat gagctgctga gcgaggtgcg cggccgcggc
    22501 ctcatgatcg gcatcgagtt cggcaggccc aagtccctga agctgcgcag ccgttggacg
    22561 atgctgcagg ccgcccgcaa gggcctgttc gcacagatgg tggtggtgcc gctgctccag
    22621 aagcaccgca tcctcaccca ggtctccggc gaccacctgg aggtcatcaa gctgatcccg
    22681 ccgctcacgg tgggggagca ggacgtcgac cggttcgtgg ccgccttcac cgccgtcatg
    22741 gacgacgcgc acagcggggg cgggctgatg tgggacttcg gcaggacgct ggtgaagcag
    22801 gcggtggcga accggtagcg cggcgggcgg gtcggccggt gcggcgggct gatccgccgg
    22861 tggcgcgcag gcagtgccgt gggtctttgc ctcaggggca agaaagttgc ccctgaggca
    22921 agcctctggc tgaatcgaag catgaaccct gccgaacccg cgggggccgc cccggagccc
    22981 ggcgacgccg ctgccgaccc gcaccccgac accgtcgccg atgccctgcc cgtcgtcgcg
    23041 ccccagctac gggacctgcg ccgccgcgcc gccctgaccc tggaggccgc ggcccgcgcg
    23101 gccggactct cgcccgcgca cctgtcccgc ctggagaccg ggcagcgcca gccgtcgctg
    23161 ccgatgctgc tcgccctcgc ccgtacctac ggtacgacgg tttccgagct tctcggcgag
    23221 acgcccgccg agcggcactc cgtcgtccgc gccgccgaca tggagcccac ggcggcgggc
    23281 ggctggacgt actggcaggc gggcgcgccc ggccggggca tgcaggcgct gcgggtgcac
    23341 gtcccgcacg gtgcgcaggg cgacatcgtg cgggtccacc cgggcgagga gtggctgtac
    23401 gtcctcaccg ggcggctgcg gctccggctc ggcgacaccg cgtacgccct cgctccgggc
    23461 gacagcgcgc acttcgactc gctgaccccg caccggatcg ccgccgcgga ccacggcggt
    23521 gccgacttcc tcttcgtcca caccttgctg cagagcccgg ccaccgcgct gtgcctcggc
    23581 ggccccaccc agggagacag gcatgacgga acctgagccg cggcggcctg aacgccggat
    23641 ggtcctggag gagaagttcc cccgcgccct gtgggtccgg ctgatcatct atgtggccgt
    23701 gggccatgtg ttcgcgttct tcgtctatct gctgttcgtg ctcggcggac agaaccagtg
    23761 acccaccagt ggggcggccc cggccgcccc gtcccggcgc ccggactcag tcgagcaggc
    23821 gctcgcgcag ccgctcccgc gtctgcggct tgacgccgag gccccgctcc agatacgtgt
    23881 cggtgtcgcc ccaggtccgc tcgatcgtct cgaaggccgc ggccagatac tcggcgcggg
    23941 cgtcgaacag cgggctcagg agctccatca cctcggggga catcgcgtcc gccgaggtgc
    24001 tgctgcggtg caccttgtag cggcggtgcg cggcgttcga ctccagatag tcggcgtgga
    24061 tcgcctcgcg ctccacgccg acggcgagca gcgtcacggc tatggacagg cccgcccggt
    24121 ccttgcccgc cgcgcagtgc atgagcgcgg gcacgctgtc ctcggcgagc gcgtgcagca
    24181 cccggctgtg ctcggccgtg cgctcctcga tgatcgtgcg gtacgaggcc gtcatccgcc
    24241 ccgccgccct gccgtccgac aggatcgagc gcagctggtc caggtcgccg tcgcggacca
    24301 tcttccagaa ctcggcgccg tcggccgggt cggacagcgg caggttcaca ttgcgcacgc
    24361 ccggcagcgc cacgtccggg ccctccaggc gctggtccgc ggcgttgcgg aagtcgaaga
    24421 tcgtgtgcag gcccagcgag ccgaggaacg cggcgtcggc gtccgtggcg tgcgcgaggt
    24481 gaccgctgcg gaagaggacg ccgtggcgca cccggcggcc gtcgagcgtc ggcagtccgc
    24541 ccacatcacg gaagttgcgc acaccggcca gctcgggctc ggtcgacggg acctgctgcg
    24601 tcacggggtc tcctcttgct cggggtgccc gggcgggccc gggtggctcc gggccgctcg
    24661 ggggcggctg cgcgcacgac ccggcgggcg cgcggcccac cgttggttgc gccttcgacg
    24721 atacgacacg ggttcctgag gcgatcagcc ctggcacggg ggtggccgga ggcgcgtaca
    24781 gggcgcgccg ggaccccgta cgcgggagtg cacaggcgtt gcccacgcgg tcgatgggcc
    24841 ggaaaatgtg cgtacgcgcg cgtgcctgtg ggaattcgtc tcgctatctg tgggggtttg
    24901 atgatcgagg tcggcggaac gggccggaca tggctcctct cgggccccac cagcagctac
    24961 gcgctgcacc tcacggaccg cgacgaactg ctgcatctgc actggggcgc gcggctcgcc
    25021 gtcgccgacg ccgaggccct cgccgccgcg ccgacgccgc ccgagcggcc cttcgaatcg
    25081 tgtcttgacg ggcgggagga gtatccggtc gagggcgggc cgaggttcgt gcggcccgcg
    25141 ctgtcggtgc ggggtggtgg ggtgcggggg acggaatggc agttcctgcg ggcggaggtg
    25201 ggggccgggg cgcaggcggc cgggggcgcc gcggctgccg agggtggcac cgacgacgca
    25261 ctccgactgc acttcaccga cgccgtgcac ggcctcctga tcaccctcgc gtaccggatg
    25321 cgcggcgacg tcgtggagcg gtacgccgtc ctcacccacc agggcccgcc gacggcaccg
    25381 gacgtggagg tcctgcgggc cgactccgcg acctggacgc tgcccctgcg cgagcgctgg
    25441 cggctgtcgc acctgcacgg gcgctgggcg gcggagtccc ggctcgtccg ctccgacctc
    25501 acctacggcg agcaggtcat cggcagtcgg cgcgggcaca ccgggcacca gcacctgccc
    25561 tgggtggccc tcgacgcgga cggcgccacc gaggagcacg gcgaggtgca cagctgtgcg
    25621 ctcgcctggt ccgggtcctg gcggatcgcc gtgcaccggc tcccggacgg cgccgtgcag
    25681 atcaccggcg gcagcgggca cgacgactcc gggcagctgc tgctcgcccc cggcgcgtcg
    25741 gtcaccacgc ccgtcttcgc ggggctgtgg accgacgggg gcttcggcgg ggcgagccgg
    25801 gcctggcacg cgtaccagcg cgcgcacgtc atcccggacg cggacgccgt ccggccggtg
    25861 ctctacaact cgtgggaggc caccgggttc gacatctccg cggagcagca gcgggccctc
    25921 gcggggcggg ccgcggagct cggcgtggag ctgttcgtcg tggacgacgc gtggttcggc
    25981 gcgcgcgtga acgaccgggc ggggctgggc gactggacgc ccaaccccga gcgcttcccc
    26041 ggcgggctca agccgctcgc cgacgaggtg cacgccctcg gcatgcggtt cgggatctgg
    26101 gtcgagccgg agatggtcaa cgtggacagc gacctgtacc gcgcgcaccc cgactgggtg
    26161 cagcaccatc ccggccgcac ccgcaccgag ttccgcaacc agctcgtcct caacctcgcg
    26221 cgcgaggacg tccaggcgta cctgtgggaa cagctcgacg cgctcctgtc cagcgcgccc
    26281 gtcgactacg tgaagtggga cttcaaccgc tgcttcaccg acccgggctg gcccggcgag
    26341 ccctacccgc aacgcttgtg ggacgcccat gtgcacgcct tctacggcct cctcgaccgg
    26401 ctgcgggccg cgcaccccgc cgtggccttc gagtcctgct cgggcggcgg tggccggatc
    26461 gacctcggcg tcctcgcccg caccgatcag gtctggacgt ccgacaacac cgacccgctg
    26521 gaccggctcg ccatccagca cgggttcagc cagatccacc ccgcgcgcgt catggccgcc
    26581 tggg
//
