LOCUS       NZ_BMVR01000007        14381 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence07, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000007
VERSION     NZ_BMVR01000007.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 524149)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14381
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14381
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..14381
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14381
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1498:4381](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1499..4381)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            <1..995
                     /locus_tag="IE274_RS19320"
                     /old_locus_tag="GCM10010349_39540"
     CDS             <5..995
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF044385.2"
                     /locus_tag="IE274_RS19320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_39540"
                     /product="nucleotide disphospho-sugar-binding
                     domain-containing protein"
                     /protein_id="WP_229909654.1"
                     /sec_met_domain="MGT (E-value: 5.8e-92, bitscore: 303.6,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AGYGDVVPWWFRLVNEPLVDELVGLCRWWEPELVVWEPGTFAGGV
                     AARVCGAAHGRLTWGVDFFGRVREQFVRLLSEAGESVGGAGDPLGAWLTVMAGRYGVAF
                     DEELTTGQFTVDQLPEAFRLETGIACLPMRYGVYNGVSVVPRWLWEAPVRPRVGFTLGL
                     SAVERLAGYSVSVVEILKALAGLEVEVVAALPGAAGIREQLGAVGDRVRVEEFVPLAAL
                     APTCAVMVHHGGFGTIGTTSLHAVPQLAIAEEIDAPILARGLAAYGAGVDLPVAEATGE
                     RVAHEVGRLLTESSFADGARRLRADMRAMPSAADVVPELVRIAERHRGR"
     misc_feature    8..10
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1499..4381)
                     /locus_tag="IE274_RS19325"
                     /old_locus_tag="GCM10010349_39550"
     CDS             complement(1499..4381)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE274_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010349_39550"
                     /product="protein kinase/lanthionine synthetase C family
                     protein"
                     /protein_id="WP_190117084.1"
                     /sec_met_domain="micKC (E-value: 8.3e-231, bitscore: 763.0,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.5e-06, bitscore:
                     20.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWSIYTLVDPVFFETPARSAAAEHLVPPRFAPLPDGWRHRAARV
                     WDMYQPELPGAADQGWKIHVSATYDNAERVLEIVAEHCLRARVPFKHLRSRSLLNAMNS
                     KYAPRPAGGKFIAVYPRDEAEFAHCARELDERLAGSDGPYILTDCRWGEGPVHFRYGAF
                     RERWCWTDDGALVLALTDADGRLVPDRRRPAFTLPEGVPVPDVLRPHIERRTAPSGDFG
                     YRVKEALHFSNAGGVYAAVRRDDGSPVVLKEARPHTGRDGAGLDATARLAHEKHVLDRL
                     ADVPGVPRAYELFDFGGHSMLAMEHLDGIPLQRWMVRHHPLVNWSACTPEGLRDYAGRA
                     EALHAEVAALVRRVHAEGIVFGDLHPGNVLVAEDAFGPGAEVATGRPAAPGTEGPPDEA
                     AASDVAAPKVRLVDFEMAFPASEDTRPTLGYPGFAARRKTGPAVDEHALAVLRLWLFLP
                     LVTSLGICPENGARLAAVAARRFGLPEDFTTTVAAALAEAPEARPQQAGERPQQAEHPG
                     GQADPPGPPKRSTVPPPVAALPDVPLDTAPVDWAAVRASMARALHTSATPDRDDRLFPG
                     DPRQFNEAPGGFAHGAAGVLWALSVAGGEREPVYEDWLLRAARADHVRPGFHDGAHGVA
                     HVLDHLGHHAAAHELIDRVRPGVEEMTDVSLYGGLAGVGLNLLHLAGGDPGHAWLKEAR
                     ELAARAVGALDDGRPHGIDRARGEPGTHGGLLHGWSGVGLFLLRMYEATGEDAYVRHAV
                     RAVHRDLDLCVARKEGVLHVDGGFRSLPYLETGSVGIGLVADLLADHADDARVTEALPA
                     LALAARSPLTVESQLFNGRAGLLAAAHTLRGHLPVAAGPEGGQAIAGPEGEQAAVDPVA
                     EHLGSLHWHALAHHGHVAFPGHSGLRLSMDLATGTAGVLTALSYVTDGGPPPLPFLHRA
                     GHPPPAADHGLPAADRRRFPCEQSVGGDTA"
     gene            complement(4530..5225)
                     /locus_tag="IE274_RS19330"
                     /old_locus_tag="GCM10010349_39560"
     CDS             complement(4530..5225)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.5"
                     /locus_tag="IE274_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_39560"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190117085.1"
                     /transl_table=11
                     /translation="MTIETPKTSGAIRVGRRVELGYATAADYGQFAKWLSPDGDVAALT
                     GDVSERVTVDVLRADAASGARFCTLRSLDGERVGMVKFHRVGGERDTTFEISGAIGSSD
                     LWSRGYGAEGFGLVVEHLFEDLGAHRLQFWVGLFNGPMLQMVMRTRFFVLEGVLRERKF
                     FKGEYHDVAMWSMLRHEYEALFIRGEWEKKPGQDAWFDTGSEPKAAARRTLTEYLRRGQ
                     DTALTPFAQ"
     gene            5426..6205
                     /locus_tag="IE274_RS19335"
                     /old_locus_tag="GCM10010349_39570"
     CDS             5426..6205
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988589.1"
                     /locus_tag="IE274_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_39570"
                     /product="TylF/MycF family methyltransferase"
                     /protein_id="WP_229909655.1"
                     /transl_table=11
                     /translation="MLAHSRDLYLDLMKKVVTNTIYQDNAHGWVRNKDFDAGLPSIQYS
                     DELRAGGRDIPRVAHTMIGGKRLDNLHACVEQVLSDDIPGDLIETGVWRGGATIFMRAV
                     LKAYDIKDRTVWVADSFEGIPKGDPVRYPGDDLAPLYRFNDVFGVSRTIVEGNFRRYGL
                     LDDQVRFLPGYFRDTLPTAPVESLAVLRMDGDLFESTMDALVHLYPKLSVGGYVIVDDY
                     RALPPCRVAVYQYRKEHGITEPIEEIDGVGVFWRRTR"
     gene            complement(6260..8014)
                     /locus_tag="IE274_RS19340"
                     /old_locus_tag="GCM10010349_39580"
     CDS             complement(6260..8014)
                     /NRPS_PKS="Domain: CAL_domain (69-493). E-value: 3.7e-113.
                     Score: 370.4. Matches aSDomain:
                     nrpspksdomains_IE274_RS19340_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="IE274_RS19340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_39580"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_190117086.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 1.6e-207, bitscore:
                     686.5, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-92, bitscore:
                     304.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIDAPRTAPRPATGFTLSALGPEPVALEYLADTVRRLAAERGDA
                     PAVTVLGDRRVRGEARRADTVVTLTYRELDERARAVAAELQSACPPGARVAILCPHDEH
                     YVVAFLGCLYAGVIAVPLYAPELFRSQTRLRSVLRDSTPGCVLTTSRVRPAVRNALSST
                     GWRHGPVLHVDEVPPHRAAKWRRPPAAPDDVAYLQYTSGSTGAPAGVRVTHANLSVAAY
                     QMRSRFMPATTAVSWVPLFHDMGLVCAIASPLSAGMHMVHLSPMGFLHRPYRWLRALSD
                     YRADWTVTPNFGLTHCVRRVTAEEVAALDLSHLRALAIGGEPVHARSVAAFVAAFADAG
                     LDHRSPVPCYGLAEATLSVTMTPNGSGAVGGHFDRAALTAGEVRPVPGGPDSVHLVSNG
                     TPVPGVRLRIADPVTGAETAGRVGEIWVGGPNRTDGYWRAPERTAQVYADGWLRTGDWG
                     FRHDGGLYVVGRMDDVIIVRGRNHYPEDIEATVESVAPVAATAIGVEGDPTERLIVLME
                     ADAAMTALPAPDREALTERIRQTVSRQHGLAVHDAVVVRSGTLPRTTSGKIQRGLCRQR
                     YAAGAYAT"
     aSDomain        complement(6536..7807)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS19340_CAL_domain.1"
                     /evalue="3.70E-113"
                     /label="IE274_RS19340_CAL_domain.1"
                     /locus_tag="IE274_RS19340"
                     /protein_end="493"
                     /protein_start="69"
                     /score="370.4"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYRELDERARAVAAELQSACPPGARVAILCPHDEHYVVAFLGCLY
                     AGVIAVPLYAPELFRSQTRLRSVLRDSTPGCVLTTSRVRPAVRNALSSTGWRHGPVLHV
                     DEVPPHRAAKWRRPPAAPDDVAYLQYTSGSTGAPAGVRVTHANLSVAAYQMRSRFMPAT
                     TAVSWVPLFHDMGLVCAIASPLSAGMHMVHLSPMGFLHRPYRWLRALSDYRADWTVTPN
                     FGLTHCVRRVTAEEVAALDLSHLRALAIGGEPVHARSVAAFVAAFADAGLDHRSPVPCY
                     GLAEATLSVTMTPNGSGAVGGHFDRAALTAGEVRPVPGGPDSVHLVSNGTPVPGVRLRI
                     ADPVTGAETAGRVGEIWVGGPNRTDGYWRAPERTAQVYADGWLRTGDWGFRHDGGLYVV
                     GRMDDVIIVRGRNHYPEDIEATVES"
     CDS_motif       complement(6551..6613)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS19340_0003"
                     /evalue="2.70E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="IE274_RS19340"
                     /protein_end="488"
                     /protein_start="467"
                     /score="19.9"
                     /tool="antismash"
                     /translation="VGRMDDVIIVRGRNHYPEDIE"
     CDS_motif       complement(6677..6757)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS19340_0002"
                     /evalue="1.80E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="IE274_RS19340"
                     /protein_end="446"
                     /protein_start="419"
                     /score="29.9"
                     /tool="antismash"
                     /translation="GRVGEIWVGGPNRTDGYWRAPERTAQV"
     CDS_motif       complement(7373..7432)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS19340_0001"
                     /evalue="9.30E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="IE274_RS19340"
                     /protein_end="214"
                     /protein_start="194"
                     /score="24.4"
                     /tool="antismash"
                     /translation="AYLQYTSGSTGAPAGVRVTH"
     gene            complement(8011..9897)
                     /locus_tag="IE274_RS19345"
                     /old_locus_tag="GCM10010349_39590"
     CDS             complement(8011..9897)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349705.1"
                     /locus_tag="IE274_RS19345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_39590"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190117087.1"
                     /transl_table=11
                     /translation="MLGTAPDTARQQDPPDTRQPEERAESGRPAILRADAWRDMLRYLR
                     PQRRRILLGGGLSLLGGFSGLIQPVIAKSVVENLESRSPVMSALIALTALVLVSAVVGA
                     IGTFILMRVSETVVLSTRREVIRRVLWLRVSETDKIPPGDLMSRATADTTLMRSAVTTA
                     IVETVNGSVMLVAILVLMGLMDWVLLLTTLAVVLLGGILVATGLPQLESAARRAQEGVA
                     ELSTALERALGTFRTIKASGAENSEAEIAERGARRAWRHSLKVARLDSLVGAFITVTIQ
                     VAFLAVLGVGGARVASGAMSLGSLIAFLLYLFYLVPPLGALVTAMIRFNVVAAAMSRVS
                     ELLRLRTEPESPVRPAPVLSDRAAAPASLTFQDVVFRYPGDGPVVHHGISFDIPAAGMT
                     AFVGPSGAGKSTVFSLIERFYEPQSGTVRMDGRDIHELDLGELRAAIGYVEQDAPVLAG
                     TIRDNLCIGMPYATEEELRRVVDQARLGELVDRLPHGLDTEVGHRGTKLSGGERQRVAV
                     ARALLRRPRLLLLDEVTSQLDARNENALREVITGITAQTTVVVVAHRLSTVSTADRIVV
                     MDGGRIRAVGTHEELLSEDALYRELAATQMLLPVSELEASAARIGDTLGERP"
     gene            complement(9878..11422)
                     /locus_tag="IE274_RS19350"
                     /old_locus_tag="GCM10010349_39600"
     CDS             complement(9878..11422)
                     /EC_number="4.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012447.5"
                     /locus_tag="IE274_RS19350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_39600"
                     /product="aromatic amino acid ammonia-lyase"
                     /protein_id="WP_190117088.1"
                     /transl_table=11
                     /translation="MITDVVESPKERLADIVRQARPDARVRPCSPLEAERMRAGVDRLA
                     RALADQEQVYGVTQGFGPLVEYAAAASDTDQGSGLIAHLGSGQGRPLSPEVCRLVVWIR
                     LNSMRLGHSAVSPEFWDRVAELWNRGFTPVIPRDGTVSASGDLQPLAHAALALAGEGEA
                     WLRDSAGNWRVRPSTEALAALGARPVTWRARQALSFVNGTSVSLAVTLLNHREVLRLAR
                     AVAALTARAVTLLGASPQAYHPGVGHARGQAGQLVAARWIREDLPPDHRRDPARPLQEP
                     YSLRCAPQVIGAVVDQLSVLEDILVREAVGCTDNPVFYEGEFLHAGNFHAMPVGLASDQ
                     IGLCLQQIAFLAERQLALLCLPETNGGRPPMLTPMPGRGSGLAGVQLSATSFVARIRQL
                     VYPAGLTALPSNGLNQDHVPMALNGANAVSDAVEQAWLVVGSLAVAVTQYAALTAPTGQ
                     PGDSPGVWADLARVSPALAADRPLASEVRGARDVLARLATELIEREEESADAGYGT"
     gene            complement(11419..12651)
                     /locus_tag="IE274_RS19355"
                     /old_locus_tag="GCM10010349_39610"
     CDS             complement(11419..12651)
                     /NRPS_PKS="Domain: AMP-binding (47-203). E-value: 2.2e-10.
                     Score: 31.6. Matches aSDomain:
                     nrpspksdomains_IE274_RS19355_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE274_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010349_39610"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_190117089.1"
                     /transl_table=11
                     /translation="MSHPELTPQEVLAAGPAAPGVNERPWLVRWDLLGEDAGELVRRTL
                     PPALDFHTSGTTGPSECWRRTRDQLWEEAGMLAALLRPERPEAVLSFAPPRHVYGALAT
                     LLVPARLGLPVWYRPHFFGAMPPSPTGRWAVVAVPWSFSALRRKLPWIAARERVALLHS
                     TAMLPSTAQDFVRDAGPGRVSVREVFGSTETGGIAWREWGPDDPPWDLFDDVEFVADAR
                     DAHDAHGIHGIHDASDVRHVPGTLGAPHPHPALDRADTDPDVPLTVRSPRLAARPGLAP
                     LDTWRTDDLVRPCGTRRFRFTGRRGGLVKINGRRVDLGALERALRAVVDCADLACLPVA
                     DELSGEHLELYVVPPPGGRLDRARVRALIAGHDLTVQPRQVHVVDRIDRSPTGLPRRIR
                     PTRPADAGAAT"
     CDS_motif       complement(11551..11709)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS19355_0002"
                     /evalue="1.00E-03"
                     /label="C2_DCL_024-062"
                     /locus_tag="IE274_RS19355"
                     /protein_end="367"
                     /protein_start="314"
                     /score="11.4"
                     /tool="antismash"
                     /translation="RVDLGALERALRAVVDCADLACLPVADELSGEHLELYVVPPPGGR
                     LDRARVRA"
     CDS_motif       complement(11686..11751)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE274_RS19355_0001"
                     /evalue="9.70E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="IE274_RS19355"
                     /protein_end="322"
                     /protein_start="300"
                     /score="18.2"
                     /tool="antismash"
                     /translation="FTGRRGGLVKINGRRVDLGALE"
     aSDomain        complement(12043..12510)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS19355_AMP-binding.1"
                     /evalue="2.20E-10"
                     /label="IE274_RS19355_AMP-binding.1"
                     /locus_tag="IE274_RS19355"
                     /protein_end="203"
                     /protein_start="47"
                     /score="31.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ALDFHTSGTTGPSECWRRTRDQLWEEAGMLAALLRPERPEAVLSF
                     APPRHVYGALATLLVPARLGLPVWYRPHFFGAMPPSPTGRWAVVAVPWSFSALRRKLPW
                     IAARERVALLHSTAMLPSTAQDFVRDAGPGRVSVREVFGSTETGGIAWREWG"
     gene            complement(12669..12932)
                     /locus_tag="IE274_RS19360"
                     /old_locus_tag="GCM10010349_39620"
     CDS             complement(12669..12932)
                     /NRPS_PKS="Domain: PP-binding (12-79). E-value: 1.5e-16.
                     Score: 52.4. Matches aSDomain:
                     nrpspksdomains_IE274_RS19360_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019819234.1"
                     /locus_tag="IE274_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_39620"
                     /product="acyl carrier protein"
                     /protein_id="WP_198898037.1"
                     /sec_met_domain="PP-binding (E-value: 4.8e-15, bitscore:
                     50.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALMNQSAALRFVAEAVEEVAGIPTEEVEPGKSLVDDLGIDSLS
                     MVEIAFTLQRQAGDEIPDEELATITTVQDLVDLVRERVEHSQ"
     aSDomain        complement(12696..12896)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS19360_PP-binding.1"
                     /evalue="1.50E-16"
                     /label="IE274_RS19360_PP-binding.1"
                     /locus_tag="IE274_RS19360"
                     /protein_end="79"
                     /protein_start="12"
                     /score="52.4"
                     /tool="antismash"
                     /translation="FVAEAVEEVAGIPTEEVEPGKSLVDDLGIDSLSMVEIAFTLQRQA
                     GDEIPDEELATITTVQDLVDLV"
     misc_feature    complement(12969..12982)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.36"
                     /tool="antismash"
     misc_feature    complement(13691..13705)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.28"
                     /tool="antismash"
ORIGIN
        1 gggcgggtta tggggatgtg gtgccgtggt ggttccggtt ggtgaatgag ccgttggtgg
       61 atgagttggt ggggttgtgc cggtggtggg agccggagtt ggtggtgtgg gagccgggga
      121 cgttcgcggg tggggtggct gcgcgggtgt gtggggccgc gcatgggcgg ttgacgtggg
      181 gggtggattt cttcgggcgg gtgcgggagc agttcgtgcg tctgctgagt gaggcggggg
      241 agtcggtggg tggggcgggg gatccgctgg gtgcgtggct gacggtgatg gcggggcggt
      301 acggggtcgc cttcgacgag gagttgacga ccggtcagtt cacggtggac cagctgcccg
      361 aggcgttccg cctggagacc ggcatcgcct gtctgccgat gcggtacggc gtctacaacg
      421 gggtgtcggt ggtgccgagg tggttgtggg aggcgccggt gcggcctcgg gtggggttca
      481 cgctggggtt gagtgcggtg gagcgtcttg ccgggtactc ggtgtcggtg gtggagatcc
      541 tcaaggccct ggccgggctc gaggtggagg tggtggccgc gctgccgggt gccgccggta
      601 tccgtgagca gctgggtgcg gtgggggatc gggtgcgggt ggaggagttc gtgccgctgg
      661 cggcgcttgc tcctacgtgt gcggtgatgg ttcatcacgg cgggttcggg accatcggga
      721 cgacctcgct gcacgccgtc ccccaactcg ccatcgccga ggagatcgac gccccgatcc
      781 tggccagggg cctggccgcg tacggagccg gggtggacct gcccgtggcg gaggcgacgg
      841 gcgaacgcgt cgcgcacgaa gtcgggcggc tgctcacgga atcctccttc gccgatgggg
      901 cacggcggct gcgggccgac atgcgggcca tgccgagcgc cgccgacgtc gtccccgaac
      961 tcgtccggat cgccgaacgg caccggggcc gctgagcgcc ggacgcacgg gacgagatcg
     1021 gggccacgcg tgcggaccgg cggacgggcg gctggaacgg gcggaacggg cggaacgacg
     1081 ggagtgagtg gggggtccct gggctcaggg accccccacc gccggctcag tcggcccggc
     1141 tggcggccgc ggtggactgc cgctgcggcc ctctcgctct catcgcctcg tcagcgggtc
     1201 agcagttcac gctgcccgtg ctgccgagca gctcgtcgtc gagggtcgac gtctccagct
     1261 cctgaagctc cagaacgttc atgcggtgtc acctcctccc aaacgctcgc tgcgggaccg
     1321 gcggcggtcg gccgccgaag tcggtggtgc gacgcggtcg gcggtctccg tggaccgccg
     1381 ctgcggttct cgcgctctcg tcgtgccgtg acagcgggtc agcaacccac gctgccggtg
     1441 ctgccgagca gctcgtcgtc gagggtcgac gtctccagct cctgaagctc cagaacgttc
     1501 atgcggtgtc acctccaacc gactgttcgc agggaaaccg gcggcggtcg gccgccggga
     1561 gtccgtggtc cgccgccggt ggcgggtgcc cggcgcggtg caggaacggc agcgggggcg
     1621 gcccaccgtc cgtgacgtac gacaaggccg tgaggacgcc cgcggtgccc gtcgccaggt
     1681 ccatggacag gcgcaggccg ctgtggccgg ggaacgcgac atggccgtgg tgggcgaggg
     1741 cgtgccagtg gaggctgccc aagtgctcgg ccaccgggtc gacggcggcc tgctcgccct
     1801 cgggaccggc gatggcctgc ccgccctcgg gaccggcggc gaccggcagg tgcccgcgca
     1861 gcgtgtgcgc cgccgcgagg agcccggccc gcccgttgaa gagctggctc tcgaccgtga
     1921 gcggcgagcg cgcggcgagc gccagcgcgg gcagcgcctc ggtgacgcgc gcgtcgtccg
     1981 cgtggtcggc cagcaggtcg gcgacgaggc cgatgccgac cgaaccggtc tccaggtacg
     2041 gcagggagcg gaagccgccg tcgacgtgca ggacgccttc cttccgcgcg acgcacaggt
     2101 ccaggtcccg gtgcacggcg cgcaccgcgt gccgcacgta cgcgtcctcg cccgtggcct
     2161 cgtacatccg cagcaggaac aggccgaccc cggaccagcc gtgcagcagc ccgccgtggg
     2221 tgccgggctc gccgcgggcg cggtcgatgc cgtgcggacg gccgtcgtcc agcgcaccga
     2281 cggcacgcgc ggccagctcc cgggcctcct tgagccaggc gtgccccggg tcgcccccgg
     2341 cgaggtgcag caggttcagg ccgacgcccg cgaggccgcc gtacaggctg acgtcggtca
     2401 tctcctcgac gccgggacgg acgcggtcga tcagctcgtg ggcggcggcg tggtggccga
     2461 ggtggtccag gacgtgcgcg acgccgtgcg cgccgtcgtg gaagccgggt cggacgtggt
     2521 cggcgcgggc cgcgcgcagg agccagtcct cgtacacggg ttcgcgttcg ccgcccgcca
     2581 cggacagggc ccacaggacg cccgcggcgc cgtgcgcgaa gccgccgggg gcctcgttga
     2641 actggcgcgg gtcgccgggg aagagccggt cgtcgcggtc gggtgtcgcc gaggtgtgga
     2701 gggcgcgggc catggaggcg cgtacggctg cccagtcgac gggggcggtg tcgaggggga
     2761 cgtcggggag ggctgcgacc gggggcggga cggtggagcg cttcggcggt cctggggggt
     2821 ccgcctggcc gccggggtgc tcagcctgct gcggccgctc accggcctgc tgtggccgtg
     2881 cctcgggcgc ctccgccagt gccgccgcga ccgtcgtcgt gaagtcctcc ggcagaccga
     2941 accgccgtgc cgccacggcc gcgagccgcg ccccgttctc cgggcagatg ccgagcgacg
     3001 tcacgagcgg caggaacagc cacagccgca gtaccgccag ggcgtgttcg tcgaccgcgg
     3061 ggccggtctt gcgacgggcg gcgaagccgg ggtagccgag ggtgggacgg gtgtcctcgg
     3121 aggccgggaa ggccatctcg aagtcgacga gccgcacctt cggcgccgcg acgtcggacg
     3181 ccgcggcctc gtccggcggc ccttccgtgc ccggcgccgc cggccggccg gtcgccactt
     3241 ccgcgccggg accgaacgcg tcctcagcca ccagcacatt cccaggatgc agatccccga
     3301 acacgatccc ctcggcgtgc acacgccgga cgagcgccgc cacctcggcg tgcagggcct
     3361 ccgcccgccc ggcgtagtca cgcaggcctt cgggcgtgca cgcgctccag ttgacgagcg
     3421 ggtggtgccg caccatccag cgctgcagcg ggatgccgtc cagatgctcc atcgcgagca
     3481 tggagtggcc cccgaagtcg aagagctcgt acgccctcgg cacgccgggg acgtcggcga
     3541 gccggtccag gacgtgcttc tcgtgggcca ggcgcgcggt ggcgtcgagg cccgcgccgt
     3601 cgcggccggt gtgcggccgg gcctccttga ggaccacggg gctgccgtcg tcgcggcgta
     3661 cggcggcgta cacgccaccg gcgttggaga agtgcagggc ctccttgacc cggtagccga
     3721 agtcgccgct cggggcggta cgccgctcga tgtgcggccg gagaacgtcg gggaccggca
     3781 cgccctcggg cagcgtgaac gcgggccgcc tgcggtcggg cacgaggcgt ccgtcggcat
     3841 cggtgagggc gagcacgagt gcgccgtcgt ccgtccagca ccagcgttca cggaaggcgc
     3901 cgtaccggaa gtgcacgggg ccctcgcccc agcggcagtc ggtgaggatg tacggcccat
     3961 cgctgcccgc gaggcgttcg tccaactcgc gtgcgcagtg ggcgaactcc gcctcgtcgc
     4021 gcgggtagac cgcgatgaac ttgccgccgg ccgggcgcgg cgcgtacttg gagttcatgg
     4081 cgttcagcag ggaccggctg cgcaggtgct tgaagggcac gcgggcccgc aggcagtgct
     4141 cggcgacgat ctccaggacg cgctcggcgt tgtcgtacgt cgcggagacg tggatcttcc
     4201 agccctggtc cgcggcgccc ggcagctcgg gctggtacat gtcccagacg cgggcggccc
     4261 ggtgccgcca gccgtcgggc agcggggcga accgcggtgg caccaagtgc tccgcggcgg
     4321 cggaccgcgc cggggtctcg aagaacaccg ggtccaccag ggtgtagatc gaccagtcca
     4381 cggacacgag gcacctccag cggaattcct ggaacgggtc ggccgtgcgt ttgacggccg
     4441 tcgcagtgat cgcctcgtgg aggtttcgat cagtaggggg agttcggaga aacgggtgcg
     4501 ggggaggggc tggggagtgt tcttagcggt tactgggcga agggggtcaa tgcggtgtcc
     4561 tggccccgcc ggagatattc cgtgagcgtc cgccgcgcgg ccgccttcgg ttcactgccc
     4621 gtgtcgaacc aggcgtcctg gccgggcttc ttctcccatt ccccgcggat gaacagggct
     4681 tcgtattcat ggcgcaacat ggaccacatc gccacgtcgt gatattcgcc cttgaagaac
     4741 ttgcgttccc tgaggactcc ttcgaggacg aagaaccggg tgcgcatcac catctgcagc
     4801 atcggcccgt tgaacaggcc cacccagaac tggagccggt gcgcgcccag gtcctcgaaa
     4861 aggtgctcca cgacgaggcc gaagccctcg gcgccatagc cccgcgacca caggtcgctg
     4921 cttccgatgg cgccgctgat ctcgaacgtc gtgtcccgtt cgccgccgac gcgatggaac
     4981 ttcaccatgc ccacgcgctc gccgtccagg gaccgcagcg tgcagaagcg tgcgcccgac
     5041 gcggcgtcgg cccgcagcac gtccaccgtg acccgctcgg acacatcgcc ggtcagggcg
     5101 gcgacgtccc cgtcggggct gagccatttc gcgaattggc cgtagtccgc ggcggtcgca
     5161 tatccgagct cgacgcggcg tccgacgcga atggccccgc tggtcttcgg cgtctcgatg
     5221 gtcatgaact cctgctttcc cggtgagtgc ggccatggtt gccccgggcg ggacgagcgt
     5281 caaccattcc cgctgattcc gcttcaatca ccgccggtac cagcgcagtt catgtgcggt
     5341 agttctgtat tccgtctcgc cggcgggaca caccggtgcc acactgctgt cgattctccg
     5401 cccggaagcg acgaggggga cgcacgtgct cgcacattcc cgcgacctgt atctggacct
     5461 catgaagaag gtcgtcacca acaccatcta ccaggacaac gcgcacggct gggtgcggaa
     5521 caaggatttc gacgccggcc ttccgagcat ccaatacagc gacgaactcc gcgccggcgg
     5581 ccgggacatc ccacgcgtcg cgcacacgat gatcggcggc aaacgcctcg acaatctgca
     5641 cgcgtgcgtc gagcaggtcc tctccgacga cattcccgga gacctcatcg agacgggggt
     5701 ctggcggggc ggcgccacga tcttcatgcg cgcggtgctc aaggcgtacg acatcaagga
     5761 ccgcacggtg tgggtcgccg actccttcga gggcatcccc aagggcgacc ccgtgcggta
     5821 cccgggcgac gacctcgcgc cgctgtaccg cttcaacgac gtcttcggcg tgtcccggac
     5881 gatcgtggag ggcaacttcc gccgctacgg actcctcgac gaccaggtgc ggttcctgcc
     5941 cggctacttc cgtgacaccc tgcccaccgc ccccgtggag agcctggccg tgctgcgcat
     6001 ggacggcgac ctgttcgagt cgaccatgga cgcgctggtg cacctctacc ccaagctgtc
     6061 cgtcggcggc tatgtgatcg tcgacgacta ccgtgcgctg cccccgtgcc gggtcgccgt
     6121 ttaccagtac cgaaaggagc acggcatcac cgagcccatc gaggagatcg acggggtcgg
     6181 cgtcttctgg cggcgtacgc ggtgacgagg gctcgtcggt gtacgcgctg acatacgcac
     6241 tgacaacggg cggtcggggt caggtcgcgt aggcccccgc cgcgtaccgc tgccggcaca
     6301 ggccgcgctg gatcttgccg ctggtggtgc gcggcagggt cccgctgcgg accaccaccg
     6361 cgtcgtggac cgcgagcccg tgctggcggc tcaccgtctg ccggatgcgc tcggtgaggg
     6421 cctcgcggtc gggcgcgggc agggccgtca tcgccgcgtc ggcctccatc aggacgatga
     6481 gccgctccgt cgggtcgccc tcgacgccga tcgccgtcgc cgcgaccggc gccaccgact
     6541 cgacggtggc ctcgatgtcc tccgggtagt ggttgcggcc ccggacgatg atgacatcgt
     6601 ccatgcggcc gaccacataa aggccgccgt cgtgccggaa gccccagtcg ccggtccgca
     6661 gccacccgtc ggcgtacacc tgtgccgtgc gctccggcgc ccgccagtag ccgtcggtgc
     6721 ggttggggcc gcccacccag atctcgccga cccggcccgc ggtctccgcg cccgtcaccg
     6781 ggtccgcgat ccgcagccgc accccgggaa ccggcgtgcc gttgctcacc aggtgcaccg
     6841 agtccgggcc gcccggcacc ggccgcacct cgcccgcggt gagcgcggca cggtcgaagt
     6901 ggccgccgac cgcgccggag ccgttgggcg tcatcgtcac ggacagcgtc gcctccgcga
     6961 ggccgtagca cggcaccggc gaccggtggt cgaggcccgc gtcggcgaag gccgccacga
     7021 acgccgccac cgaccgcgcg tgcacgggct ccccgccgat ggccagcgca cgcaggtggc
     7081 tgaggtcgag ggccgccacc tcctcggcgg tgacgcgccg gacgcagtgg gtgaggccga
     7141 agttgggcgt gaccgtccag tcggcgcggt agtccgacag ggcgcgcagc cagcggtagg
     7201 ggcggtgcag gaaccccatc gggctcaggt gcaccatgtg cattccggcg ctgaggggac
     7261 tcgcgatcgc gcagacgagc cccatgtcgt ggaagagcgg cacccaggac acggccgtcg
     7321 tcgcgggcat gaagcgcgaa cgcatctggt acgccgccac cgacaggttc gcgtgcgtga
     7381 cccgcacccc cgcgggcgcc ccggtggagc ccgacgtgta ctgcaagtac gccacgtcgt
     7441 ccggcgccgc gggcgggcgc cgccacttcg ccgcccggtg cggcggcacc tcgtcgacgt
     7501 gcagcacggg cccgtgccgc caccccgtgc tgctcagcgc gttgcgcacc gccgggcgca
     7561 cccgcgacgt cgtcaggacg cagcccgggg tgctgtcccg cagcaccgaa cgcagccgcg
     7621 tctgactgcg gaacagctcc ggcgcgtaca gcggcaccgc gatgacaccc gcgtacagac
     7681 agccgaggaa ggcgaccaca tagtgctcgt cgtgcgggca caggatcgcc acgcgggccc
     7741 cgggcggaca cgccgactgg agctcggccg cgacggcccg ggcccgctcg tccagttccc
     7801 ggtacgtcag cgtgacgacc gtgtccgcgc gccgggcctc gccccgcacc cggcggtcgc
     7861 cgagcacggt cacggcgggc gcgtcgccgc gctcggccgc gaggcggcgc accgtgtcgg
     7921 ccaggtactc cagggcgacc ggctcgggcc cgagcgccga cagcgtgaag ccggtggccg
     7981 gcctgggcgc ggtacgcggt gcgtcgatgc tcatgggcgc tctcccaggg tgtcgccgat
     8041 gcgggcggcg gacgcttcga gctcgctgac cggcagcagc atctgcgtcg cggcgagttc
     8101 gcggtacagc gcgtcctcgc tcagcagctc ctcgtgggtg ccgacggcgc ggatgcggcc
     8161 gccgtccatc acgacgatcc ggtcggccgt gctgacggtg gacaggcggt gcgcgaccac
     8221 cacgaccgtg gtctgcgccg tgatgccggt gatgacctcc cgcagggcgt tctcgttgcg
     8281 ggcgtcgagc tgcgaggtca cctcgtcgag cagcagcagc cgtggccggc gcagcagcgc
     8341 gcgggccacg gcgacccgct gccgctcacc gccggacagc ttggtgccgc ggtggccgac
     8401 ctcggtgtcg aggccgtgcg ggagccggtc gacgagctcg ccgaggcggg cctggtcgac
     8461 gacgcggcgc agctcctcct cggtggcgta cggcatgccg atgcacaggt tgtcgcgaat
     8521 ggtcccggcg aggacggggg cgtcctgctc gacgtagccg atggcggcgc gcagttcgcc
     8581 caggtccagt tcgtggatgt cccggccgtc catgcgcacg gtgccgctct gtggctcgta
     8641 gaaccgctcg atcaaggaga acaccgtgga cttgcccgcg ccggaggggc ccacgaaggc
     8701 ggtcatcccg gcggcgggga tgtcgaagct gatgccgtgg tgcaccacgg gcccgtcgcc
     8761 gggatagcgg aagacgacgt cctggaacgt cagcgacgcg ggcgccgccg cccggtccga
     8821 cagcaccggg gccgggcgca ccgggctctc cggctcggtg cgcagccgca gcagctcgct
     8881 gacgcgggac atcgcggcgg ccaccacgtt gaaccggatc atcgcggtga ccagcgcgcc
     8941 cagcggcggc acgaggtaga agaggtagag caggaacgcg atcagactgc ccaggctcat
     9001 cgcgccggac gccacccggg cgccgccgac accgaggacg gcgaggaacg ccacctggat
     9061 cgtcacggtg atgaaggcgc cgaccagcga gtcgagccgg gccaccttca ggctgtgccg
     9121 ccaggcccgg cgcgcgccgc gctcggcgat ctcggcctcg ctgttctccg cgccggacgc
     9181 cttgatggtg cggaaggtgc cgagcgcccg ctccagggcg gtgctcagct cggccacgcc
     9241 ctcctgggcg cggcgcgcgg cgctctccag ctgcggcagg ccggtggcga cgaggatgcc
     9301 gccgagcagc accacggcca gcgtggtcag cagcagcacc cagtccatca ggcccatcag
     9361 gacgaggatc gcgacgagca tcaccgagcc gttgacagtc tccacgatcg cggtggtgac
     9421 ggcgctgcgc atcagtgtgg tgtcggcggt ggcccgcgac atcaggtcgc ccggcgggat
     9481 cttgtccgtc tcggacaccc gcagccacag cacccggcgg atcacctcgc ggcgcgtgct
     9541 gaggacgacc gtctcggaga cccgcatcag gatgaacgtg ccgatcgcgc cgaccaccgc
     9601 cgacaccagc acgagagccg tcagcgcgat cagcgccgac atgacggggg agcgcgactc
     9661 caggttctcc accacggact tggcgatcac gggctggatc aggcccgaga agccgccgag
     9721 cagcgacagg ccgccgccga ggaggatgcg cctgcgctgc ggccgcagat agcggagcat
     9781 gtcccgccag gcgtcggcgc gcagaatggc cggacggccg gactccgccc gctcctcggg
     9841 ctgtcgggtg tccggcgggt cctgctgccg cgcggtgtca ggtgccgtac ccagcatctg
     9901 cgctctcctc ctcgcgttcg atgagctcgg tggcgaggcg cgcgaggacg tcgcgggccc
     9961 cgcgcacctc ggacgccagc ggccggtcgg ccgccaacgc gggggagaca cgggccaggt
    10021 cggcccacac gccgggggag tcgccgggct gcccggtggg cgcggtgagc gccgcgtact
    10081 gcgtcaccgc gaccgcgagc gagcccacga ccagccacgc ctgttcgacg gcgtcgctca
    10141 cggcgttcgc gccgttgagg gccatcggca cgtggtcctg gttgaggccg ttgctgggca
    10201 gcgccgtcag gcccgccggg tagacgagct ggcggatgcg ggcgacgaac gaggtcgcgc
    10261 tgagctgcac cccggcgaga ccgctgccgc ggccgggcat cggggtgagc atgggcggcc
    10321 tgccgccgtt ggtctccggc aggcacagca gggcgagttg gcgctcggcg aggaacgcga
    10381 tctgctgcag gcacaggccg atctggtcgg aggcgaggcc caccggcatc gcgtggaagt
    10441 tgcccgcgtg caggaactcg ccctcgtaga agaccgggtt gtccgtacag cccaccgcct
    10501 cccggaccag gatgtcctca agaacggaca gttggtcgac gaccgcgccg atcacctgcg
    10561 gcgcgcagcg caggctgtac ggctcctgca gcgggcgtgc cggatcgcgg cggtggtccg
    10621 gcggcaggtc ctccctgatc caccgggcgg cgaccaactg ccccgcctgg ccgcgggcat
    10681 gacccactcc ggggtggtac gcctgcgggc tcgcgccgag cagcgtcacc gcgcgcgcgg
    10741 tgagcgccgc gaccgcgcgg gccaggcgca gcacctcccg gtggttgagc agcgtgacgg
    10801 ccaggctcac gctggtgccg ttgacgaagg acagggcctg ccgggcccgc cacgtcaccg
    10861 ggcgcgcgcc gagcgcggcc agggcctccg tggacggccg cacccgccag ttccccgcgc
    10921 tgtcgcgcag ccacgcctcg ccctccccgg ccagggcgag cgccgcgtgc gcgaggggct
    10981 gcaggtcgcc gctcgcgctg accgtgccgt cgcgagggat caccggagtg aagccccggt
    11041 tccacaactc ggccacccgg tcccagaatt cgggcgacac ggccgagtgg ccgagccgca
    11101 tgctgttgag ccggatccac accaccagac ggcagacctc cggggacagc ggccgcccct
    11161 ggccgctgcc gaggtgggcg atgagcccgc tgccctggtc ggtgtccgac gcggcggccg
    11221 cgtactcgac cagcgggccg aacccctgcg tgacgccgta cacctgctcc tggtcggcga
    11281 gggcccgggc gagccggtcg acaccggccc gcatgcgctc cgcctccagc gggctgcacg
    11341 ggcgcacccg ggcgtcgggg cgggcctggc gcacgatgtc cgccaggcgt tccttcggcg
    11401 actcgactac gtctgtgatc atgtggcggc tcctgcgtca gcgggtcggg tggggcggat
    11461 ccggcgcggc aggccggtcg gggagcggtc gatgcggtcg acgacgtgca cttggcgggg
    11521 ctggacggtg aggtcgtggc ccgcgatgag cgcgcgcacg cgggcccggt cgagacggcc
    11581 gcccggcggc ggcacgacgt acaactccaa gtgctcgccg ctgagttcgt cggcgacggg
    11641 caggcaggcg agatccgcgc agtcgacgac ggcgcgcagc gcgcgctcca gcgcgccgag
    11701 gtccacccgg cggccgttga tcttcacgag accaccgcgc cgtccagtga aacggaaccg
    11761 ccgtgtcccg cagggccgta cgaggtcgtc ggtgcgccag gtgtcgaggg gagcgaggcc
    11821 ggggcgggcg gcgaggcggg ggctgcggac ggtcaggggg acgtcggggt cggtgtccgc
    11881 gcggtcgagg gcgggatggg ggtggggggc gccgagagtg ccggggacgt gccgcacgtc
    11941 ggaggcgtcg tggatgccgt ggatgccgtg ggcgtcgtgg gcgtcccgcg cgtcggcgac
    12001 gaactccacg tcgtcgaaca ggtcccacgg cggatcgtcc ggaccccact cccgccaggc
    12061 gatgccgccc gtctccgtgg acccgaacac ctcccgcacc gacacccgcc cggggcccgc
    12121 gtcccggacg aagtcctgag cggtggacgg cagcatcgcg gtgctgtgga gcagggcgac
    12181 gcgctcgcgg gccgcgatcc acgggagctt gcggcgcagc gccgagaacg accagggcac
    12241 cgcgaccacc gcccaccggc ccgtgggcga cggcggcatg gcaccgaaga agtgcgggcg
    12301 gtaccagacg ggcagcccga gtctggccgg gacgagcagg gtcgcgagcg ccccgtacac
    12361 gtgccggggc ggcgcgaacg acaggacggc ctcggggcgt tcgggccgca gcagcgcggc
    12421 cagcatgccc gcctcctccc agagctggtc gcgggtgcgc cgccagcact cgctggggcc
    12481 ggtcgtgccg gacgtgtgga agtccagcgc cgggggcagc gtccggcgga ccagctcccc
    12541 ggcgtcctcg ccgagcaggt cccaacggac cagccagggg cgctcgttga cgccgggagc
    12601 ggcggggccc gcggccagga cttcctgcgg ggtcagctcg ggatggctca ccaggtcacc
    12661 tcgtgtcgtc actgactgtg ttcaacccgt tcccgtacca ggtccacgag atcctgcacc
    12721 gtggtgatcg tggccagctc ctcgtcgggt atctcatcgc ccgcctgccg ctggagcgtg
    12781 aaagcgatct ccaccatgga gagggaatcg atcccgagat cgtccaccaa ggacttaccg
    12841 ggctccacct cttcggtcgg aattccggct acttcttcca ccgcctcggc gacaaaacga
    12901 agtgcggcgc tctggttcat gagtgcgtcc atggctatct cctatttcat cgaagcgcgc
    12961 acggtcaatg catgactgtc cggatcccat tgagaaatgc cgagaaacgg tctgtcgtgc
    13021 ccggtcagaa gtgtcgcgga cggaatatcg gcaggttgtt gtccacttgt ggtccggggg
    13081 cgtgcgccgg taagtacgcg gatgtcccgg gggcttggcg gcggcatcgg tacccgtccg
    13141 cgccggtccc gccgccgacc gtcccgccgg cgggacgccg tgccgcgtcc cggacccgac
    13201 cctgcccacc gccccggaac ccggcccgcg acacccggtc gcgcacatcc ggaacggcca
    13261 gccggcgcgc ggtccccgcc tcccggccga ccacccgcgt tgcgaaaagc gcaggcgcgc
    13321 tcggagcctc cgcatgacac ggcgacgcgc cgaaaccgcg gggaatcaga ccgtgccgga
    13381 aggcgatcaa ccgcatgtcc cggtccgggt tcgccgtcgg cccatccgga acaaccggcc
    13441 attcattccc ctggacaccg cgccgtgacc tgccgcagac tgccggagtc tcgggacgac
    13501 tcggggcagg tgagagtaca gcacgctcac acggaggatg tcttgccaag caagaggcac
    13561 gggggaatac ctcccggcgt gaggccgcta ccgcactcga ttccgacagc gattcccaac
    13621 cagatttcca acccgattcc cagaactatt gcaggaggtc tttcgagaga ccataatccg
    13681 ccgaacgtgc aggaacggaa attcggatcg cagctccatg tgaacgcgtc cgtggtggcc
    13741 cggcgcacct cgctcgacct gccggtcgac ctcccgctgg accgctggcg gagcctcggc
    13801 gcgcacatcg ccgtcatcgc cgactcgtcg agctggtggc tgggggactg gctcatctac
    13861 ggccaggccc actaccccga ccgctacaag atcgccctcg ccgacacctc cctgagctac
    13921 cagacgctgc gcaactacgc ctgggtcgcg ggccggttcg gcgtggcgcg gcggcgcgga
    13981 cggctcagct tccagcacca cgccgaggtg gcgggcctgg acgagcgggc ccaggaccac
    14041 tggctggaac aggccgaacg gcacggctgg tcccgcaacg aactgcgccg ccacatcagg
    14101 gagagcctgc gcgcacccga acgcagaccg gtgggggagg cggcacggcc gggtcccgag
    14161 ctcgggtccg ggaccgcttc cgggtccggc gacacgcagg cggccatccg cttcaagatc
    14221 acaacagagc ggcgcatccg ctggcagaag gccgcggcca accagggcca ggccctcgcc
    14281 gagtggatcg tctccgtact cgaccgctgc gcgcccgcga cggtgcgccc cgccaccgag
    14341 agctgtaccg ccgacctccc gcaccacccg gtcctcgccg g
//
