LOCUS       NZ_BMVR01000003        13273 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000003
VERSION     NZ_BMVR01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 754944)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 652389
            Orig. end                         :: 665662
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13273
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="5"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13273
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13273
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8273](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8273
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    216..230
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(712..1662)
                     /locus_tag="IE274_RS09970"
                     /old_locus_tag="GCM10010349_20230"
     CDS             complement(712..1662)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642313.1"
                     /locus_tag="IE274_RS09970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20230"
                     /product="ABC transporter permease"
                     /protein_id="WP_190115251.1"
                     /transl_table=11
                     /translation="MTTLTSKTPAATPEPVAAGSGPWRLARAELRRRTSAKISLVIVAL
                     FAVMAIAAPLLSALGGWSPEEFDKTAVDPYLGGQPIGALGGISADHWLGVEPVTGRDLF
                     ARVVHGAQVSLLIAFAATAIVVIAGTAAGVAAGYFGGRVDAVLSRIMDLTMSFPSLIFM
                     IAMMSVAKDVNRILLMTAVIGLFGWPGIARVVRGQTLSLKHREYVDAARVGGSGPWRIL
                     TRDILPGVAGPVIAYTTLIIPGMIATEAALSYLGVGVRPPTPSWGQMIAESVAFYDTDP
                     MYFVIPSTCLFLTVLAFTLLGDALRDILDPRGSRT"
     gene            complement(1677..3419)
                     /locus_tag="IE274_RS09975"
                     /old_locus_tag="GCM10010349_20240"
     CDS             complement(1677..3419)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006608092.1"
                     /locus_tag="IE274_RS09975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20240"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_190115252.1"
                     /transl_table=11
                     /translation="MNKRTLTAVAAVLATAVTLGTAGCSGSGSGKGRGGKNPATLNAGA
                     VVGGTPQRGGTLTVLSNQDFTHLDPARNWVMNDMDFGTRLLYRTLVTYKAAPGTAGGEL
                     VPDLAADLGTPSNGARTWTFRLKKGIKYEDGTPVTAQDIKYNVERSFSPDLPGGADYAA
                     RYLAGAKGYQGPAEGRHLDSVKTPDAHTIVFELRKPFAEFRNVTVMPTFAPVPKKRDKG
                     PQYDNRPFSSGPYKVDSYQRGKKLVLVRNPHWKASTDSVRKAHPDKLVMVMGLKANQID
                     DRLIASQGADASAVSWGAVRPESAAKVLPSAEVKKRLIAESTNCTDMVQMHTGRGPFSE
                     VKVRQAVQYALDRESVLTASGGPAFNDPSTAYMPASLFGGKQPDTLKVPVAGDVAKAKQ
                     LLKEAGKPGGFSTKMTVSTGDKGRAEAIQESLGKAGIKVTIETVDPSAFYATIGDTKNR
                     TDLVYTGWCPDYPSGSTFLPFVFDGRYIKEKGNTGNHSLFRDKPTMRRMDEIAAMTDAK
                     KAGAAWRELDGEILAKAPTVPVLVRRWPLVLGSNIAGAYGQTSFGGQLDYATVGLKDPS
                     KSNG"
     misc_feature    3461..3471
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    complement(3485..3501)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.66"
                     /tool="antismash"
     misc_feature    complement(3487..3497)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    complement(3532..3546)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.0"
                     /tool="antismash"
     gene            3543..4910
                     /locus_tag="IE274_RS09980"
                     /old_locus_tag="GCM10010349_20250"
     CDS             3543..4910
                     /EC_number="3.4.11.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965659.1"
                     /locus_tag="IE274_RS09980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20250"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_372447164.1"
                     /transl_table=11
                     /translation="MPVNEPASTGIRTVSHDLPESPEFASFMARDWAPTPLPDGIRLPA
                     ADLTPARRARLSARFPGERLIVPAGELRVRSNDCDYRFRPHSAYAWLTGLTGEDQAGHV
                     LVLEPDGPGGHEAVLHLRPRSPRTDNGFYRDRRYGEFWVGRRADLAEAERTTGVRCVPL
                     TGLPPGRNAAEDHELATVLSELRLIKDPWEVGQLQLAVDHTTAGFEDVVRALPRALAHP
                     RGERWIEGVFGLRARTEGNGTGYETIAASGAHACVLHWIRNDGPLDARELLLLDAGVET
                     DSLYTADITRTLPLSGRFSPVQRQVYELVLAAQDAGIAALRPGARFRDFHRAAMRVIAE
                     GLADWGVLKNADGEFHRRYTLCSSGHMLGIDLHDCAQARAETYLDGELAEGQVLTVEPG
                     LYLQPDDETLPRELRGIGVRIEDDLVITADGARLMSGALPRTPDGVEEWMGTLLAG"
     misc_feature    4972..4989
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.27"
                     /tool="antismash"
     gene            5001..6155
                     /locus_tag="IE274_RS09985"
                     /old_locus_tag="GCM10010349_20260"
     CDS             5001..6155
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891271.1"
                     /locus_tag="IE274_RS09985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20260"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_190115254.1"
                     /sec_met_domain="DAO (E-value: 1.9e-66, bitscore: 220.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRNSSDVIVVGAGVVGAACAYYAAQAGLTVTVVDRGPVSGGTT
                     GSGEGNLLVSDKEPGPELELALLSIELWRELTELLPPQIEYETKGGLVVAAAEAGMSAL
                     RDFAAGQEKAGVRAEEIAADRLHDLEPHLAPGLAGGFHYPQDAQVMPALAAAHLLKAGG
                     DRVRLRLGEEVTGLLTGGHGELRGVSTATGELYAAYVVNAAGTWGGEFAALAGVDLPVL
                     PRRGFVLVTEPLPRVVRRKVYAADYVADVASGSAALQTSAVVEGTAAGPVLIGASRERV
                     GFDRTLSTEVLRRLAAQATALFPVLAGVRAMRTYAGFRPYLPDHLPAIGPDPRVPGLLH
                     ACGHEGAGIGLAPATGLIVARCLTGGRPPLDIGPFDPGRFLPRP"
     gene            6296..6616
                     /locus_tag="IE274_RS09990"
                     /old_locus_tag="GCM10010349_20270"
     CDS             6296..6616
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309276.1"
                     /locus_tag="IE274_RS09990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20270"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_190115255.1"
                     /sec_met_domain="Fer2_4 (E-value: 7.6e-25, bitscore: 82.2,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARARTPADLVGAQPGPSFEITFDGRPVPALPGQSVAAALWAADI
                     LAWRTTRVGGRPRGAFCGIGQCYDCLATINGTPNRRACLVPAGPGDAITTQEGHGHDRL
                     GV"
     gene            6597..8273
                     /locus_tag="IE274_RS09995"
                     /old_locus_tag="GCM10010349_20280"
     CDS             6597..8273
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004938968.1"
                     /locus_tag="IE274_RS09995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20280"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_190115256.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.6e-21, bitscore:
                     72.1, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 3.2e-11, bitscore:
                     38.8, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASASESPGSTEPTEPTEPTEPTEPTEPTEPSGPSRLYDLAVIG
                     AGSAGLAGAVTAAELGLSVALLDTATGTGGQFYRHPAPAVGALRPEALHHDWSAYAGLR
                     RRLEASTVTRLGGHHVWTVSREGASGDGAFGEGAFREGASREGVFGDGEGPWTVHAVTG
                     ADGCAERPVRVWARAVLLATGAYERQLPFPGWTVPGVIGAGGAQAMLKSGLVLPGKRVV
                     VAGSGPLLLAVASSLAAAGARVPAVIEASGYLAYARHPRVLAANPHKLAEAVVHGGTLL
                     RHRVPLRTRSAVTEVHGRDRVEAVTVTRLDRDWRPLPGTARRIACDAVAVGHGLVPQIE
                     LATTLGCATRTTPDRATALLLDDLQETSVPDLWAAGETGGIGGARLARAEGELAGLAIA
                     ARLRGRPAHRGRVRELQRRRDRMRAFADAMAAAHAPGAGWSRWLTDDTDVCRCEEVTAG
                     SIRAAVADLGARDARTVKLLTRAGMGWCQGRMCGSGVACLAAGDGVGEPPAERRPFATP
                     VPLAALASLDEPADAGNAPADAGNAPGDAGRDPARGAHHPC"
     misc_feature    8356..8369
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.4"
                     /tool="antismash"
     misc_feature    complement(8357..8370)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.04"
                     /tool="antismash"
     misc_feature    8361..8377
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.88"
                     /tool="antismash"
     misc_feature    8365..8375
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            8399..9307
                     /locus_tag="IE274_RS10000"
                     /old_locus_tag="GCM10010349_20290"
     CDS             8399..9307
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006608088.1"
                     /locus_tag="IE274_RS10000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20290"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_190115257.1"
                     /transl_table=11
                     /translation="MTDTAWNTARPWRGIMVATALPLRDDLTVDYDAYAEHVRWLIDSG
                     CDGVVPNGSLGEYQTLTDEERARVVHTAVEAAGDPARVMPGVAAYGSAEARRWAERAAA
                     AGCGSVLLLPPNAYRADEQAVRDHYAEVAKAGVPVVAYNNPFDTKVDLSPALLAALHRD
                     GSIVAVKEFTGDVRRAYEIAELAPELDLLIGADDVLLELAVAGAVGWIAGYPNALPASC
                     AELFHAAVAGDLTTALPLYRSLHSLLRWDSKTEFVQAIKLSMDIVGRRGGPVRPPRSPL
                     TEEIERGVREATEKAVAHGHR"
     gene            9363..10367
                     /locus_tag="IE274_RS10005"
                     /old_locus_tag="GCM10010349_20300"
     CDS             9363..10367
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="IE274_RS10005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20300"
                     /product="proline racemase family protein"
                     /protein_id="WP_190115258.1"
                     /transl_table=11
                     /translation="MRTRHVFHAVDSHTEGMPTRVITGGVGIIPGTTMAERRLHFIENM
                     DHLRTLLVYEPRGHAAMSGAILQPPTRPDADYGVLFIEVSGLLPMCGHGTLGVATVLVE
                     TGMVPVTEPVTTVRLDTPAGLVPVDVRVEDGAVRSATFTNVPAFCVGLERKAEVPGFGT
                     VTYDLAFGGNFYAFVDLDALGLPFDRARKEDLLAAGLGLMDAINASPDRPVHPERPDIA
                     GVKHVYLAAPGSDAHHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLDRDFVNE
                     SFIGTKFTGRLIGEAEVGGAPAVVPTITGRAWVTGTAQYFLDPDDPFPGGFLL"
     gene            10394..11773
                     /locus_tag="IE274_RS10010"
                     /old_locus_tag="GCM10010349_20310"
     CDS             10394..11773
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891276.1"
                     /locus_tag="IE274_RS10010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20310"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_190115371.1"
                     /sec_met_domain="Aldedh (E-value: 1.3e-121, bitscore:
                     401.6, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSPSTFTSVNPADPADVVLTFTAPGAFAAVDTVERARAAQAGWL
                     LGGAAARSSALGAVAAAVEAAAAELAALAVREVGKPLAEARAEVARTAAIWRYYAQAPY
                     DPVGAVHESAAGAGLLLSRRRPHGVAGLITPWNFPLAIPSWKAAPALAVGNAVVLKPAP
                     EATACARRLAEIVQQVLPAGVFTVLPGGATEGNALVSASDVVSFTGSTGVGQAVVRTAT
                     AHGIPVQAEMGGLNAAIVLPDADIDRAAAHIAAAIAGYAGQKCTATSRVIAVGAALDPL
                     REALGEALRAVPVGDPADPATVCGPLIGARARDQVGDAVHGLSVLAGGTVPDGPGWYAA
                     PTLVEKVPPGHRLLSEEVFGPVAALLPAEGLDHAVRITNSVPHGLVTSLHTADLDAALG
                     GLDHLDTGMVRINAPSTGVDFHLPFGGTKASSHGPREQGRAALDFYATTRTYTLAPAKT
                     A"
     gene            11877..13142
                     /locus_tag="IE274_RS10015"
                     /old_locus_tag="GCM10010349_20320"
     CDS             11877..13142
                     /NRPS_PKS="Domain: Abhydrolase_1 (43-270). E-value:
                     1.6e-19. Score: 62.5. Matches aSDomain:
                     nrpspksdomains_IE274_RS10015_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543022.1"
                     /locus_tag="IE274_RS10015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_20320"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_190115259.1"
                     /sec_met_domain="PF00561 (E-value: 5.2e-20, bitscore: 67.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPAHSTVDHLFTVPLDHSAPTGPTIQVFAREVVDPGRADERLPW
                     LLYLQGGPGGKSPRPSAGSPGWLDEALKTYRVLLLDQRGTGRSTPVTARAAARFADPAR
                     LAAYLGHFRADAIVADAELIRRQLCGDEPWETLGQSYGGFLTLTYLSRAPEGLKACYVT
                     GGLPGLTATADDVYARTYPRVRDRVHAFYARYPENVTRLRRIADLLTATDVRLPDGDRL
                     TVRRLRTLGLVLGMGDGFERTHWLLDEALDAEGELTDTFLHQVMAVTGFTDNPLFAVMQ
                     ETLYGQGAGPTGWAASRALEDFAEFTEKADPLLLTGEMIYPWMFHDIAGLRPFADAADL
                     LARRTDWPPLYDLDRLAANKVPVAAIVYHDDMYVDAGLSLRTACQVGAVRVWVTNEWEH
                     DGVTASGGRVLERLTAMAAGRA"
     aSDomain        12006..12686
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS10015_Abhydrolase_1.1"
                     /evalue="1.60E-19"
                     /label="IE274_RS10015_Abhydrolase_1.1"
                     /locus_tag="IE274_RS10015"
                     /protein_end="270"
                     /protein_start="43"
                     /score="62.5"
                     /tool="antismash"
                     /translation="PWLLYLQGGPGGKSPRPSAGSPGWLDEALKTYRVLLLDQRGTGRS
                     TPVTARAAARFADPARLAAYLGHFRADAIVADAELIRRQLCGDEPWETLGQSYGGFLTL
                     TYLSRAPEGLKACYVTGGLPGLTATADDVYARTYPRVRDRVHAFYARYPENVTRLRRIA
                     DLLTATDVRLPDGDRLTVRRLRTLGLVLGMGDGFERTHWLLDEALDAEGELTDTFLHQV
                     MAVTG"
ORIGIN
        1 ggcgcggcag acccttggcg cgggcggtgc ggatgtacgg ctcggccatc gtctcgatca
       61 tcgaactgcg gctctggcgg gcgtacatgg ccgcgtagag gatggcgagc gcgagccagg
      121 ggagcagcag gttcgacgcc cagtcgaggg ggtcggagcc gaagggcacg tactgcggat
      181 agggcagcag gtcggccgtc cggatcagcc cgtagatcag catcatcgac gtgaagtaca
      241 cgggcaggga ggcggcgccg accgcgccga ccatcaggag cttgtcggtg agggtgtcct
      301 tgcgcagcgc ggccgtcacc cccgcggtga ggccgagcgc cagccacagc acggccgcgc
      361 cgagcgcgag cgaggcggag accggcagcc ggtccatgag caggccccac acggcttcgc
      421 tgttctcgta gctgtagccg aggcacggga agtcgcaccg cagggcgtac tggccggtgc
      481 cgatggtgcg gccggtgaag atcccggcca ggaaatccca gaactgctgc cagatgggct
      541 ggtccaggcc catgttggcg cggatggccg caaggcgttc ggtgctgcag gacttgccgc
      601 aggccgcggc ggccgggtcg gacggcagga cgtagaagat ggtgaaggtg acggcggcga
      661 tggcgatgag cacgcccgtc acggccagca ggcggcggcc gatgtacagg atcatgtgcg
      721 gcttcccctc gggtcgagga tgtcccgcag cgcgtcgccg agcagggtga acgcgagcac
      781 ggtcaggaac agacaggtgc tcgggatgac gaagtacatg gggtccgtgt cgtagaaggc
      841 gacgctctcg gcgatcatct ggccccagga gggcgtcggc ggccggacgc cgacaccgag
      901 gtagctcagc gccgcctcgg tggcgatcat gccggggatg atcagggtgg tgtacgcgat
      961 gacgggcccg gcgacgccgg gaaggatgtc gcgggtgagg atccgccagg gacccgagcc
     1021 gcccacgcgg gcggcgtcga cgtactcgcg gtgcttgagc gagagggtct ggccgcgcac
     1081 cacgcgggcg atgccgggcc agccgaacag gccgatgacg gcggtcatca ggaggatccg
     1141 gttgacgtcc ttggccaccg acatcatcgc gatcatgaag atcagggagg ggaaggacat
     1201 ggtgaggtcc atgatccggc tgaggacggc gtcgacgcgg ccgccgaagt aaccggccgc
     1261 gaccccggcc gccgtgcccg cgatcacgac gatcgccgtg gcggcgaagg cgatgagcag
     1321 ggagacctgg gcgccgtgca cgacccgggc gaacaggtcg cggccggtga cgggttcgac
     1381 gcccagccag tggtcggcgg agatcccgcc gagcgccccg atgggctgcc cgccgaggta
     1441 ggggtcgacc gcggtcttgt cgaactcctc gggcgaccag ccgcccaggg cgctcagcag
     1501 cggagcggcg atcgccatga cggcgaagag cgcgacgatg acgagggaga tcttcgccga
     1561 ggtgcggcgg cggagttccg cgcgggcgag gcgccagggg ccgctgcccg ccgcgaccgg
     1621 ttccggagtg gccgcggggg tcttcgaggt gagggtggtc atggtcgggg cgcccctcag
     1681 ccgttgctct tggacgggtc cttgaggccg accgtggcgt agtcgagctg gccgccgaag
     1741 gacgtctggc cgtacgcgcc cgcgatgttg ctgccgagga ccagcggcca gcggcgcacc
     1801 aggaccggga cggtcggggc cttggcgagg atctcgccgt ccagctcccg ccaggcggcg
     1861 ccggccttct tggcgtccgt catggcggcg atctcgtcca tgcgccgcat ggtcggcttg
     1921 tcgcggaaca gcgagtggtt gcccgtgttg cccttctcct tgatgtagcg gccgtcgaag
     1981 acgaagggca ggaacgtcga gccggacgga tagtccgggc accagcccgt gtagaccagg
     2041 tcggtgcggt tcttggtgtc gccgatcgtg gcgtagaacg cggacgggtc gacggtctcg
     2101 atggtgacct tgatcccggc cttgccgagc gactcctgta tcgcctcggc ccggcccttg
     2161 tcgccggtgg agacggtcat cttggtcgag aacccgcccg gcttgcccgc ctccttcagg
     2221 agctgcttgg ccttggcgac gtcaccggcg acggggacct tgagggtgtc gggctgcttg
     2281 ccgccgaaga gcgacgccgg catgtaggcc gtcgacgggt cattgaacgc ggggccgccg
     2341 gaggcggtga gcaccgactc ccggtcaagg gcgtactgca ctgcctgacg gaccttcacc
     2401 tcgctgaacg ggccgcgtcc ggtgtgcatt tggaccatgt cggtgcagtt ggtggactcg
     2461 gcgatcagcc gcttcttgac ctcggcgctc ggcagcacct tggcggcgct ctcgggccgc
     2521 accgctcccc aggagacggc ggaggcgtcc gcgccctgcg aggcgatgag ccggtcgtcg
     2581 atctggttgg ccttgaggcc catcaccatc acgagcttgt ccgggtgggc cttgcgcacc
     2641 gagtcggtcg aggccttcca gtgcgggttg cgcacgagca ccagcttctt cccgcgctgg
     2701 tacgagtcga ccttgtaggg gccggacgag aagggcctgt tgtcgtactg cgggcccttg
     2761 tcgcgcttct tcggcaccgg cgcgaacgtc ggcatcacgg tgacgttgcg gaactccgcg
     2821 aagggcttgc gcagttcgaa gacgatcgtg tgggcgtcgg gcgtcttcac ggagtcgagg
     2881 tgcctgccct cggccgggcc ttggtagccc ttggccccgg cgaggtagcg ggccgcgtag
     2941 tcggcgccgc cgggcaggtc gggggagaag gaccgctcga cgttgtactt gatgtcctgg
     3001 gcggtgacgg gggtgccgtc ctcgtacttg atgcccttct tcaggcggaa ggtccaggtc
     3061 ctggccccgt tggagggggt gccgaggtcg gccgcgaggt cggggacgag ttcgccgccc
     3121 gcggtgccgg gggcggcctt gtaggtgacg agggtgcggt agagcagccg ggtgccgaag
     3181 tccatgtcgt tcatcaccca gttgcgggcc gggtcgaggt gggtgaagtc ctggttggac
     3241 aggacggtca gggtgccgcc gcgctgcgga gtgccgccga ccacggcccc ggcgttgagc
     3301 gtcgcgggat tcttgccgcc ccgtcccttg cccgaaccgg agccggaaca gcccgccgtg
     3361 ccaagggtga cggccgtcgc caggacggcg gcgacggcgg tgagggtgcg cttgttcatc
     3421 agtggtcact ccgagaacag tcggccagcc cgaacgtggc tggaatgtga ccggtaacat
     3481 agtaatgtga aattgtactg gcaaggcatc gacccgtccg ttactcacct gtgtccgaag
     3541 ggatccctgt gaacgagccc gcgtcgaccg gcatccgcac ggtcagtcac gaccttcccg
     3601 aatcacccga gttcgcgtcc ttcatggccc gcgactgggc cccgaccccg ctgccggacg
     3661 gcatccggct gcccgccgcc gacctcaccc cggcccgccg cgcccgcctc tcggcccgct
     3721 tccccggcga acgcctgatc gtcccggcgg gggagctcag ggtccgctcg aacgactgcg
     3781 actaccgctt ccgcccgcac agcgcctacg cctggctgac cggactcacc ggtgaggacc
     3841 aggcgggcca tgtgctggtt ctcgaacccg acgggccggg cggccacgag gcggtgctgc
     3901 acctgcgccc ccggtccccg cgcaccgaca acgggttcta ccgggaccgc cgctacggcg
     3961 agttctgggt gggccgccgc gccgacctcg cggaggccga gcgcacgacc ggcgtccggt
     4021 gcgtgccgct caccggcttg ccgccgggcc ggaacgccgc cgaagaccat gaactcgcca
     4081 ccgtcctgag cgagttgagg ctcatcaagg acccctggga ggtcggccag ctccagctcg
     4141 ccgtcgacca caccacggcc gggttcgagg acgtcgtccg cgccctgccg cgcgccctcg
     4201 cccacccccg cggcgagcgc tggatcgagg gcgtcttcgg gctgcgcgcc cgcaccgagg
     4261 gcaacggtac cggctacgag accatcgccg cgtccggcgc ccacgcctgt gtactccact
     4321 ggatacgcaa cgacggcccc ctggacgcaa gggagttgct gctgctcgac gcgggcgtgg
     4381 agaccgacag cctctacacc gccgacatca cccgcaccct cccgctctcc gggcgtttct
     4441 ccccggtcca gcggcaggtc tacgaactcg tcctcgcggc gcaggacgcg ggcatcgccg
     4501 cgctgcggcc cggcgcccgc ttccgcgact tccaccgggc cgccatgcgc gtcatcgccg
     4561 aagggctcgc ggactggggg gtgctgaaga acgccgacgg tgagttccac cggcgctaca
     4621 ccctgtgcag cagcgggcac atgctcggca tcgacctcca cgactgcgcc caggccaggg
     4681 ccgagacgta tctcgacggc gagctggcgg aggggcaggt gctcactgtc gaacccggcc
     4741 tctacctcca gccggacgac gagaccctgc cccgcgaact gcgcggcatc ggcgtgcgca
     4801 tcgaggacga cctcgtcatc acggcggacg gggcccggct gatgtcgggc gcgctgccga
     4861 ggacgccgga cggggtggag gagtggatgg ggacgttgct ggcgggctga gcgcggcgcg
     4921 ggacgccgcc ggacggctga accgaggacc ggtcgcgcga aagccttggc atcgtcagtg
     4981 ccatgtgaaa tattactgac gtgctcacga gaaactcctc ggacgtcatc gtcgtcggcg
     5041 ccggcgtcgt cggcgcggcc tgcgcctact acgccgcgca ggccggcctc accgtcaccg
     5101 tggtcgaccg cggcccggtc tcgggcggca ccaccgggtc cggcgagggc aacctcctcg
     5161 tctccgacaa ggagccgggc cccgagctcg aactggccct gctctccatc gaactgtggc
     5221 gggagctgac cgaactgctc ccgccgcaga tcgagtacga gaccaagggc ggcctggtcg
     5281 tcgccgccgc cgaggccggg atgagcgccc tgcgagactt cgcggccggg caggagaagg
     5341 ccggggtgcg ggcggaggag atcgcggccg accggctcca cgacctggag ccgcacctgg
     5401 cccccggcct cgcgggcggc ttccactatc cccaggacgc ccaggtcatg cccgccctgg
     5461 ccgccgccca cctgctgaag gcgggcggcg accgggtgcg cctcaggctc ggcgaggagg
     5521 tcaccggcct gctcaccggc ggccacggcg aactgcgcgg ggtcagcacg gcgaccggcg
     5581 agctgtacgc cgcgtacgtg gtgaacgccg cgggcacctg gggcggcgag ttcgccgcgc
     5641 tcgcgggcgt ggacctgccg gtgctgcccc gccggggctt cgtcctcgtc accgaaccgc
     5701 tgccgcgcgt ggtgcggcgc aaggtgtacg cggccgacta cgtcgccgac gtcgccagcg
     5761 gttcggcggc gctgcagacc tcggcggtcg tcgagggcac cgcggcgggc ccggtcctga
     5821 tcggcgcgag ccgggaacgg gtcggcttcg accgcaccct gtccacggag gtcctgcggc
     5881 gcctcgcggc ccaggcgacc gccctcttcc cggtcctcgc cggggtccgg gcgatgcgta
     5941 cgtacgccgg gttccggccc tacctccccg accacctgcc cgcgatcggc cccgacccgc
     6001 gcgtccccgg tctgctgcac gcctgcggcc acgagggcgc gggcatcggc ctcgccccgg
     6061 ccaccgggct gatcgtggcg cggtgcctga ccggcggccg accacccctg gacatcggcc
     6121 cgttcgaccc gggccgcttc ctgcccaggc cctgaccggc acctgctgcc atgtctgacc
     6181 agctcccgcc gcgacgccga gccctgcccg cgatgcctga ccagcccctg ctcccacgcc
     6241 tgaccagccc ctaccgcgac gcctgaccag ctgctgctac gagaggaggc ccaccgtggc
     6301 ccgtgcccga acccccgccg acctggtcgg cgcgcagccc ggcccgtcgt tcgagatcac
     6361 cttcgacggc cgccccgtcc ccgccctgcc ggggcagtcc gtcgccgccg cgctgtgggc
     6421 cgcggacatc ctggcctggc gcaccacccg ggtgggcggg cggccgcgcg gcgccttctg
     6481 cggcatcggg cagtgctacg actgcctcgc caccatcaac ggcacgccca accgccgggc
     6541 ctgcctggtg cccgccggtc ccggcgacgc gatcacgacc caggaagggc acggccatga
     6601 ccgcctcggc gtctgaatct cctggctcga ccgaaccgac cgaaccgacc gaaccgaccg
     6661 aaccgaccga accgaccgaa ccgaccgaac cgtcggggcc gtcccggctg tacgacctcg
     6721 cggtgatcgg cgcgggctcg gccggtctcg ccggagccgt gaccgccgcc gaactcggcc
     6781 tgtccgtcgc cctgttggac acggcgaccg gcaccggcgg gcagttctac cggcacccgg
     6841 caccggccgt cggcgccctg cgccccgaag ccctgcacca cgactggtcc gcctacgccg
     6901 ggctccggcg acgcctggag gcgagcacgg tgacccgtct cggcgggcac cacgtgtgga
     6961 ccgtgtcccg ggagggcgcc tctggtgacg gcgcttttgg cgagggcgcc ttccgggagg
     7021 gcgcctcccg tgagggcgtc ttcggggacg gcgaagggcc ctggaccgta cacgccgtca
     7081 ccggcgccga cggctgcgcg gagcggccgg tgcgggtatg ggctcgtgcg gtgctcctcg
     7141 ccaccggcgc gtacgaacgc caactcccct tccccggctg gacggtgccc ggcgtgatcg
     7201 gggccggggg agcgcaggcc atgctcaagt ccggcctcgt gctgcccggc aagcgggtcg
     7261 tggtggccgg gagcggcccg ctgctgctcg cggtcgcctc ttcgctggcc gccgccgggg
     7321 cccgggtgcc cgccgtgatc gaggcctccg gctacctggc gtacgcccgc cacccgcgcg
     7381 tcctcgcggc caacccgcac aagctggccg aggcggtggt gcacggcgga acgctgctgc
     7441 gccaccgcgt gccgctgcgc acccgcagcg ccgtcaccga agtgcacggc cgggaccggg
     7501 tggaggccgt cacggtcacc cggctcgacc gggactggcg gccgctgccg ggcacggcac
     7561 gccggatcgc ctgcgacgcg gtcgccgtcg gtcacggcct cgtaccgcag atcgaactgg
     7621 ccacgacgct cggctgcgcg acccgcacca cccccgaccg cgccacggcc ctcctcctgg
     7681 acgaccttca ggagacatcg gtgccggacc tgtgggcggc gggcgagacc gggggcatcg
     7741 gcggcgcccg actggcgcgt gcggaaggtg agctggcggg cctcgcgatc gccgcccggc
     7801 tgcgcggccg ccccgcccac cgaggccgtg tccgggaact ccagcgccgc cgcgaccgca
     7861 tgcgggcctt cgccgacgcc atggccgccg cgcacgcccc cggggcgggc tggtcgcgct
     7921 ggctgaccga cgacacggac gtctgccggt gcgaggaggt caccgcgggc agcatccgcg
     7981 cggcggtcgc cgatctcggg gcccgggacg cgcgcaccgt caagctcctc acccgcgcgg
     8041 gcatgggctg gtgccagggg cggatgtgcg ggtcgggcgt ggcctgcctc gcggcgggcg
     8101 acggggtggg ggagccgccc gcggagcgcc gaccgttcgc gacgccggtg ccgctggcgg
     8161 cgctcgcctc gctcgacgaa ccggccgatg ccgggaacgc gcccgccgat gccgggaacg
     8221 cgcccggcga cgcgggacgc gaccccgccc ggggcgccca ccacccctgc tgaccccgca
     8281 cctacccggc ttgccgactc ccaggctccc cggctccttt accccatgac cccggccccc
     8341 ttgtgggccc cacccatcct tcaataaaat gtcacacact atagagaggt cgtccgtcat
     8401 gaccgacacc gcctggaaca ccgctcgccc ctggcgcggc atcatggtcg ccaccgccct
     8461 gccgctccgg gacgacctga ccgtggacta cgacgcgtac gccgagcacg tccgctggct
     8521 gatcgacagc ggctgcgacg gcgtcgtccc caacggctcg ctcggcgagt accagacgct
     8581 caccgacgag gagcgcgccc gcgtggtgca caccgccgtc gaggcggcgg gcgatcccgc
     8641 ccgcgtcatg cccggcgtcg ccgcctacgg cagcgccgag gcccgccgct gggccgagcg
     8701 ggccgccgcg gccgggtgcg gctcggtcct gctgcttccc cccaacgcct accgcgccga
     8761 cgagcaggcc gtacgggacc actacgccga ggtcgccaag gccggggtgc cagtcgtggc
     8821 gtacaacaac ccgttcgaca ccaaggtcga cctcagcccc gccctgctcg ccgcgctgca
     8881 ccgggacggc tcgatcgtcg ccgtcaagga gttcaccggc gatgtgcgca gggcctacga
     8941 gatcgccgaa ctcgccccgg aactcgacct gctgatcggt gccgacgacg tactgctcga
     9001 actcgccgtg gccggggccg tcggctggat cgcgggctac cccaacgccc tgcccgcctc
     9061 ctgcgccgag ctcttccacg ccgccgtcgc cggtgacctg accacggccc tgccgctcta
     9121 ccggtccctg cactccctgc tccgctggga ctccaagacc gagttcgtgc aggccatcaa
     9181 gttgtccatg gacatcgtcg gccgccgcgg cggccccgtc cgcccgcccc gctccccgct
     9241 cacggaggag atcgagcgcg gcgtgcggga agccaccgag aaggccgtcg cccacggcca
     9301 ccgctgaccg cgaccgccgt gcaccgagcc gtccgcaacc gcccgctccg aaaggactcc
     9361 ctgtgcgtac gcgtcatgtc ttccacgccg tcgactcgca caccgagggc atgcccacgc
     9421 gcgtgatcac cggtggcgtc gggatcatcc ccggcaccac catggccgag cgcaggctgc
     9481 acttcatcga gaacatggac cacctccgca cgctgctcgt gtacgagccg cgcggacacg
     9541 ccgcgatgag cggagcgatc ctccagccgc ccacccgccc cgacgccgac tacggcgtgc
     9601 tgttcatcga ggtctccggc ctgcttccga tgtgcggtca cggcaccctc ggcgtcgcga
     9661 ccgtcctggt ggagaccggc atggtcccgg tcaccgaacc ggtcaccacg gtgcgcctcg
     9721 acaccccggc cggactcgtc cccgtcgacg tacgcgtcga ggacggggcc gtcaggtccg
     9781 ccacgttcac caatgtgccc gcgttctgcg tcggcctgga gcgcaaggcc gaggtccccg
     9841 gcttcgggac ggtcacctac gacctcgcct tcggcggcaa cttctacgcc ttcgtcgatc
     9901 tcgacgccct gggcctgccg ttcgaccgcg cccgcaagga ggacctgctc gccgccgggc
     9961 tcggcctgat ggacgccatc aacgcgtcgc cggaccgccc cgtccacccg gagcggcccg
    10021 acatcgccgg ggtcaagcac gtctacctgg ccgcccccgg ctccgacgcg caccactccc
    10081 ggcacgccat ggccatccac ccgggctggt tcgaccgctc cccgtgcggt accggcacct
    10141 cggcccggat ggcccagttg cacgcccgcg gcgagctgcc cctggaccgc gacttcgtca
    10201 acgagtcctt catcggtacg aagttcaccg gccgcctcat cggcgaggcg gaggtcggcg
    10261 gggcgcccgc cgtcgtaccg accatcaccg gccgcgcctg ggtcaccggc accgcccagt
    10321 acttcctcga cccggacgac cccttccccg gaggcttcct cctgtgaccg ccgccgtatc
    10381 ccccctgtcc gccatgccgt ccccgtccac gttcacctcc gtcaacccgg ccgaccccgc
    10441 cgacgtcgtc ctgaccttca ccgcgccggg cgccttcgcc gccgtggaca ccgtcgagcg
    10501 ggcccgcgcc gcccaggccg gatggctgct cggcggggcg gccgcccgct cgtccgccct
    10561 cggcgcggtc gccgccgccg tcgaggccgc ggcggcggag ctggccgcgc tcgccgtgcg
    10621 cgaggtgggc aagccgctcg ccgaggcgcg cgccgaggtc gcgcgcaccg ccgcgatctg
    10681 gcggtactac gcccaggccc cgtacgaccc cgtcggcgcc gtccacgaga gcgccgccgg
    10741 ggccgggctg ctgctcagcc gccgcaggcc gcacggcgtc gccggtctca tcaccccgtg
    10801 gaacttcccg ctcgccatcc cgagctggaa ggcggccccg gcgctcgccg tcggcaacgc
    10861 ggtggtcctc aagcccgccc cggaagccac ggcctgcgcc cggcgcctgg ctgagatcgt
    10921 ccaacaggtc ctgcccgccg gggtgttcac cgtgctgcca ggcggcgcca ccgagggcaa
    10981 cgcgctcgtc tccgcctccg acgtggtctc cttcaccggc tcgaccggcg tcggccaggc
    11041 ggtcgtgcgc accgccaccg cccacggcat cccggtccag gccgagatgg gcggcctgaa
    11101 cgcggccatc gtcctgccgg acgccgacat cgaccgggcg gccgcgcaca tcgccgccgc
    11161 gatcgccggt tacgcgggcc agaagtgcac cgccaccagc cgcgtgatcg ccgtcggcgc
    11221 ggccctcgac ccgctgcgcg aggcgctcgg cgaggcgctg cgggccgtcc cggtcggcga
    11281 cccggccgac ccggccaccg tgtgcgggcc gctcatcggc gcgcgcgccc gcgaccaggt
    11341 cggcgacgcc gtgcacggcc tgagcgtgct cgcgggcggc acggtgccgg acgggcccgg
    11401 ctggtacgcg gccccgaccc tggtggagaa ggtgccgccc ggccatcggc tgctgtccga
    11461 ggaggtcttc ggccccgtcg cggccctgct gcccgccgag ggcctcgacc acgcggtccg
    11521 gatcaccaac tccgtcccgc acggcctggt cacctcgctg cacaccgcgg acctggacgc
    11581 cgccctcggt ggcctcgacc acctcgacac cggcatggtc cggatcaacg ccccgtccac
    11641 cggcgtcgac ttccacctgc cgttcggcgg cacgaaggct tccagccacg gcccccgcga
    11701 acagggccgg gcggccctcg acttctatgc cacgacccgg acctacaccc tggcgcccgc
    11761 gaagacagcg tgacgcccgg ttccggtgat gcccctgcgg gccggtgagg ctggtcgcgc
    11821 agttccccgc gcccctgaca gggcccccgg tgccgtcccc tccagaagaa gggcccatga
    11881 accccgctca ctcgaccgtc gaccacctct tcaccgtccc cctggaccac tccgctccca
    11941 ccgggccgac catccaggtc ttcgcccgcg aggtcgtcga cccgggacgc gctgacgagc
    12001 ggctgccgtg gctgctctat ctgcagggcg gtccgggcgg caagtccccg cgtccgtcgg
    12061 ccggttcgcc gggctggctg gacgaggcgc tcaagaccta ccgggtgctg ctgctcgacc
    12121 agcgcggcac cggccgctcg acccccgtca ccgcccgggc cgccgcccgc ttcgccgacc
    12181 cggcccgact ggccgcgtat ctgggccact tccgcgccga cgcgatcgtc gccgacgccg
    12241 agctgatccg ccgtcaactc tgcggtgacg agccctggga gaccctcggt cagagctacg
    12301 gcggcttcct caccctcacc tatctgtccc gcgcacccga ggggctcaag gcctgctacg
    12361 tcaccggggg cctgcccgga ctcacggcca ccgccgacga cgtctacgcc cgcacctacc
    12421 cgcgcgtccg cgaccgcgtg cacgcgttct acgcccgcta cccggagaac gtcacccggc
    12481 tgcgccggat cgcggacctc ctcacggcca ccgacgtccg cctgcccgac ggggaccgcc
    12541 tcaccgtccg ccgcctgcgc acgctcgggc tcgtcctcgg catgggcgac gggttcgagc
    12601 ggacccactg gctgctcgac gaagccctcg acgccgaggg ggagttgacc gacaccttcc
    12661 tgcaccaggt gatggccgtg accggcttca ccgacaaccc gctgttcgcc gtgatgcagg
    12721 agacgctcta cggccagggc gcgggcccca ccggctgggc cgcgtcccgc gccctggagg
    12781 acttcgccga gttcaccgag aaggcggacc cgctcctgct caccggcgag atgatctacc
    12841 cctggatgtt ccacgacatc gcgggcctgc gccccttcgc ggacgccgcc gacctgctgg
    12901 cccgacgcac cgactggccc ccgctgtacg acctcgaccg cctggcggcc aacaaggtcc
    12961 cggtcgccgc gatcgtctac cacgacgaca tgtacgtgga cgccggtctc tccctgcgca
    13021 ccgcctgcca ggtcggcgct gtccgggtct gggtcaccaa cgaatgggag cacgacggcg
    13081 tcaccgcctc cggcggccgg gtgctcgaac gcctgacggc gatggccgca ggccgcgcct
    13141 agggcctgtc cggtgggtcg ccgcgacgcc gcgccgaccc accggacagg ccctggttcc
    13201 gccggttccg caccactcgg gagagacatg cccgcacagc acctccgcct gcgcccgttg
    13261 accgcggcgt tca
//
