LOCUS       NZ_BMVR01000002        21077 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000002
VERSION     NZ_BMVR01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 777077)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 330387
            Orig. end                         :: 351464
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21077
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21077
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21077
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11077](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11077)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(532..547)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            540..1169
                     /locus_tag="IE274_RS05280"
                     /old_locus_tag="GCM10010349_10620"
     CDS             540..1169
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645680.1"
                     /locus_tag="IE274_RS05280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10620"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_190114388.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPARHKDSLTSVDAIRELFGENQQAARR
                     ATDSDVTRFRSVRARLRGVFEAADGGDETLAVDLLNSLLLEFPVSPQISGHDYRDDDGR
                     PLWHMHLADHPSNVTAGYAAIAAMGLAFHLTEYGVDRLGLCEATPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLESERSASTGRTAKKVQETSAASES"
     gene            complement(1073..1534)
                     /gene="sodX"
                     /locus_tag="IE274_RS05285"
                     /old_locus_tag="GCM10010349_10630"
     CDS             complement(1073..1534)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535213.1"
                     /locus_tag="IE274_RS05285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10630"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_190114389.1"
                     /transl_table=11
                     /translation="MPETTADGRETRVPFQLIEVDGPSMVPTLNPGDWMLVRHGARVRP
                     GDVVILRHPLQQDLLVVKRAVERRDGGWWVLGDNPYNAGGDSTVYGVVPEELVLARVRA
                     RFRPLSRFREEREARGRRQLSLAALVSWTFLAVRPVLADRSLSRRLRAR"
     gene            1702..2097
                     /gene="sodN"
                     /locus_tag="IE274_RS05290"
                     /old_locus_tag="GCM10010349_10640"
     CDS             1702..2097
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="IE274_RS05290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10640"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_030359892.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKASAHCDLPCGVYDPAQARIEAESVKAVQEKMAAN
                     DDAHYQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHTLVNDTLKALSAAKA
                     SADPKTGEKALELIAEIDRIFWETKKA"
     gene            2458..4524
                     /locus_tag="IE274_RS05295"
                     /old_locus_tag="GCM10010349_10650"
     CDS             2458..4524
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483987.1"
                     /locus_tag="IE274_RS05295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10650"
                     /product="translation factor GTPase family protein"
                     /protein_id="WP_190114390.1"
                     /transl_table=11
                     /translation="MQSHALQLTQSRQHTLNLGILAHIDAGKTSLTERLLHAAGVIDEI
                     GSVDAGSTQTDSLALERQRGITIKSAVVSFAIDDVSVNLIDTPGHPDFIAEVERVLSVL
                     DGAVLVVSAVEGVQAQTRVLMRTLRRLAIPTLVFVNKVDRRGADPERVLAELARKLTPA
                     IAPMGTVRAPGGHAARYVPYAADDPLFTGRLAELLAEHDDALLSAYVEDEAAALAPRGL
                     RAALADQTRRARVHPVFFGSAMTGTGLDALTGAVKELLPAAAGAADGPVAGTVFKVERG
                     PSGEKVAYARLFSGTVRVRDRVALAGREPEQEHADDSKVTAVSVFEQGAAVRRDAVAAG
                     QIAKLWGLTRVRIGDVLGDARHVPERHTTAHHFAPPTLETVVAPRHAADRAALHAALTQ
                     LAEQDPLIDLRQDALRQEISVSLYGEVQKEVIEATLADEFGVGVEFRESTTLCVERVVG
                     TGAHTEFIDTDPNPFLATVGLRVEPAPAGKGVEFRLGVELGSMPYAFFKAVEDTVRETL
                     AQGLHGWEVPDCLVTMTHSGYWPRQSHAHAVFDKSMSSTAGDFRQLTPLVLMDALRRAG
                     TRVHEPMHRFRLTVPADVFGTLLSALGRLRAVPHAPTAHGSTYVIDGVIPAAHVHGLEQ
                     ALPGLTRGEGELESAFDHYAPVTGTPPARPRTDHNPLDRKEYVQRVTRRTRVG"
     misc_feature    complement(2492..2507)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     misc_feature    complement(2493..2510)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.02"
                     /tool="antismash"
     gene            complement(4528..5577)
                     /locus_tag="IE274_RS05300"
                     /old_locus_tag="GCM10010349_10660"
     CDS             complement(4528..5577)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551828.1"
                     /locus_tag="IE274_RS05300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10660"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_190114391.1"
                     /transl_table=11
                     /translation="MDGRDLLAQRFEEHRPRLKAVAYRMLGSLSEAEDAVQETWLKLSR
                     VDDERVENLGGWLTTVVGRVCLDLLRARKQRGEQPLDVQASDTHVPDPEVSPLPGGRDA
                     VDPEQEALLADSVGLALLVVLDTLSPAERLAFVLHDMFAVPFEDIAPIVERAPAATRQL
                     ASRARRRVRGSDPAPAPDTDRTRHRQVVEAFLAAARKGDFDALLELLDPGVVLRADGGG
                     AEGLSRLVRGATAVVAGARSFSTLAPTTYLALVNGKVGQIAVHDGRAFSVGEFTVRDGR
                     IVEINILADQERLRELVDERTVAAVTSAGPAAGADAGAGTATDAGADAGTNTADGTSST
                     ADGTPPTAD"
     misc_feature    5558..5572
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.32"
                     /tool="antismash"
     misc_feature    5652..5667
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.17"
                     /tool="antismash"
     gene            complement(5917..6627)
                     /locus_tag="IE274_RS05305"
                     /old_locus_tag="GCM10010349_10670"
     CDS             complement(5917..6627)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610235.1"
                     /locus_tag="IE274_RS05305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10670"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_190114392.1"
                     /sec_met_domain="HAD_2 (E-value: 6.5e-10, bitscore: 34.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRHGGKPQLPFGGQSHLPPDRTSHLPSDRNSHLPFDVVLTDLDG
                     VIRFYDMSDVAELERAAGLPEGATAEVAFAPETDLPLMLGRIGKSEWADSIAAGLARGH
                     GLAPAHGRELGIALADSKFWADQTVVGLLRRARAHVRVSIVTNATPWLDDDLALLGLNT
                     LVDDVVSSAVLGVVKPDRRIYEVAAERLGVAVTRCLFVDDREENVDAAVALGMTGVLYR
                     GPDDLETALGPVLG"
     gene            complement(6624..7649)
                     /locus_tag="IE274_RS05310"
                     /old_locus_tag="GCM10010349_10680"
     CDS             complement(6624..7649)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE274_RS05310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010349_10680"
                     /product="hypothetical protein"
                     /protein_id="WP_190114393.1"
                     /transl_table=11
                     /translation="MKVTWGVRGSRRVAVAVAVVALAALAGCGSTTGGSGGGAARGSGV
                     PEVDDEKDLTGLPLERYEFSARDHERREDASARFTQRCMRSHGFPDFPLRWRDQGIDMS
                     SSRTAVAISTTLYGSLDLGGARSRGYGLDREALKAFEKKRAPKGRLITPDENTMLFGIG
                     MPPGDDSAAGRASGAGGRKAPEDGGHEVPKAGCVQVGARRVVADVKDETRMTAYVVGRR
                     AAIDKAVAKDPRMRRALDTWADCVVDKGFKRYASPEAAFRDKAWHRGSDGDTRRTRRER
                     DTAVADIECKREHNTAGVWRTVAAERQRRDISRHRSAYEAVRADQERVRSTVRSVLGAG
                     G"
     gene            complement(7756..8160)
                     /locus_tag="IE274_RS05315"
                     /old_locus_tag="GCM10010349_10690"
     CDS             complement(7756..8160)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE274_RS05315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010349_10690"
                     /product="hypothetical protein"
                     /protein_id="WP_190114394.1"
                     /transl_table=11
                     /translation="MGSDGRRSGPRPQSDPVCKHCGRPVGTAIKRRKVLGAYVPVWAPA
                     PCHNPECDACVADEPDEKSRAGRGYKSKHKPGHLPRHAPEAGTKAAAEPAPEIDLESGA
                     TATAPQAVPEVASRTGAQAEPKPRPEPDPP"
     gene            complement(8205..8804)
                     /locus_tag="IE274_RS05320"
                     /old_locus_tag="GCM10010349_10700"
     CDS             complement(8205..8804)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645673.1"
                     /locus_tag="IE274_RS05320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10700"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_190114395.1"
                     /transl_table=11
                     /translation="MRKLTYFVAVSIDGFIGDPTGDANSFMPFVDEEFLGFLKTEYPET
                     VSATGRKILGFGDGVPNEKFDTVIQGRGSYQLGLDEGEPSPYGHLREYVASHSIGESPS
                     PNVEIITDDLLGKVRALKAEDGELGIWLCGGAQVAGQLIDEVDELVLKTYPVLLGSGMP
                     MFGGVESAVSEFELASSRIFGNGVVVRTYSRKRGKD"
     gene            complement(9065..9664)
                     /locus_tag="IE274_RS05325"
                     /old_locus_tag="GCM10010349_10710"
     CDS             complement(9065..9664)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973719.1"
                     /locus_tag="IE274_RS05325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10710"
                     /product="N-acetyltransferase"
                     /protein_id="WP_190114396.1"
                     /transl_table=11
                     /translation="MGVPIRRAGESDRAEVVGLLDEAFMRDPVSSWVFPDEQRRRRRHG
                     ALMGAFLDMAFAEGYVDLAEDGSGVALWWSVPAGPPPGDAADGPVQLRQAVDPDNERVE
                     TIGRLASEIHPSDRPHQYLHMIGVKPERQGEGIGSALVAPVLARCDREGLHAYLEASSP
                     RGRELYLRLGFTDLGSPLDLPDGPRMWPMWREPRAV"
     gene            complement(10001..11077)
                     /locus_tag="IE274_RS05330"
                     /old_locus_tag="GCM10010349_10720"
     CDS             complement(10001..11077)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998011.1"
                     /locus_tag="IE274_RS05330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10720"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_190114397.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.7e-56, bitscore:
                     184.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTDMTECAPRPRGQVLGEGYEAAEILTSARLCVDPELRAAVE
                     SLPGSLRRIALYHFGWEHADGTPAAGNVGKAIRPALVLAAVRALGGDPLSAVRAAAAVE
                     LTHNFTLLHDDVMDRDATRRHRPTAWTVFGDSDAILAGDALQALAQRLLAEDPHPGAPA
                     AAARLAACVVELCAGQQADRALESRGPDEVSLTECLAAAEAKTGALLGCACAIGAVYAG
                     AGADEVEALDGFGRQAGLAFQLIDDVIGIWGDPTRTGKPARADLAARRKSLPVVAALAS
                     GTPEGAALAGLYGRGSDQGDLDRMARAVEGAGGRDWAQLHAADRMSRALGELARAVPDP
                     ERAGGLLALAEFVTRRSH"
     gene            complement(11208..12614)
                     /locus_tag="IE274_RS05335"
                     /old_locus_tag="GCM10010349_10730"
     CDS             complement(11208..12614)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="IE274_RS05335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10730"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_190114398.1"
                     /transl_table=11
                     /translation="MSVGEEIRSEQDQPQQSLGTSAARNLATTTKSAPQMQEISSRWLL
                     RMLPWVQVQGGTYRVNRRTSYSVGDGRVTFVKTGDRVEVIPAELGELPVLRDFEDQEVL
                     SELARRCQQREFEAGGVLTSFGNQADEVFLLAHGRAEKIGTGPYGDDTVLGTLADGAYF
                     GDQALIDPETIWEYTVRAVTACTVLTLPRQDLEQVAERSESLRAHLDRLRAIPVQRTNN
                     YGEAAIDLSSGHVGEAVLPGTYVDYESRPREYELSVAQTVLRIHTRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELINNREFGLLNNCEYDQRLQPHDGVPSPDDMDELLTRRRGSK
                     LFLAHPRAIAAFGRECNKRGLVPETIEVSGNRIPTWRGVPIFPCNKIPVTEERTSSIIC
                     MRTGEDEQGVVGLHQAGIPDEIEPSLSVRFMGISDQAIISYLVSTYYSAAVLVPDALGI
                     LENVEIGRWR"
     misc_feature    complement(12919..12930)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(12979..12989)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            12984..13217
                     /locus_tag="IE274_RS05340"
                     /old_locus_tag="GCM10010349_10740"
     CDS             12984..13217
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535203.1"
                     /locus_tag="IE274_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10740"
                     /product="hypothetical protein"
                     /protein_id="WP_190114399.1"
                     /transl_table=11
                     /translation="MAGFLDRAREQVQQGLNQGKQKLDDVQAQRAGNDLLKQLGAAYYA
                     ERRGSGTPDATQQALAALEAHIATHGDGFLRA"
     gene            13363..13956
                     /locus_tag="IE274_RS05345"
                     /old_locus_tag="GCM10010349_10750"
     CDS             13363..13956
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142330.1"
                     /locus_tag="IE274_RS05345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10750"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_190114400.1"
                     /transl_table=11
                     /translation="MAPPMSANRFLDLLRDEGVTVVEVGNWREHNRNHVGPWGPVHGVM
                     IHHTVTSGSELTVRLCRDGHSTLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDDVLRA
                     VIAEKRLPPDNEANTDGNRHFYGFECENLGDGEDPWTDEQLDAIERVSAAVCRHHGWTE
                     RSVIGHLEWQPGKIDPKGFTMDAMRDRIGERLKG"
     gene            14055..14966
                     /locus_tag="IE274_RS05350"
                     /old_locus_tag="GCM10010349_10760"
     CDS             14055..14966
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639608.1"
                     /locus_tag="IE274_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10760"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_190114401.1"
                     /sec_met_domain="PALP (E-value: 1.3e-21, bitscore: 72.6,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATPPTSALRPRLPTPLQPVMDPRFEARDVRLLLKRDDLIHPDL
                     PGNKYRKLALNLEQARAAGHRTLLTFGGAYSNHLRATAAAGRLLGFATVGVVRGDELAD
                     RPLNTSLAQCAADGMRLHFVDRSMYRQKADPAVLTGLQRATAAEDAYVIPEGGSNALAV
                     QGCVALGAELRGRTDVAAVACGTGGTLAGLAAGLGPGQRALGIPVLKGGFLGPEIAGLQ
                     RAAFGVPGTNWSLDDRFHCGGYARTTAELTAFADDFEQRHGVPVERVYVAKLLYALTVL
                     SEEGAFAPGTTVTAVITGTPSA"
     gene            complement(15059..16657)
                     /locus_tag="IE274_RS05355"
                     /old_locus_tag="GCM10010349_10770"
     CDS             complement(15059..16657)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639610.1"
                     /locus_tag="IE274_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10770"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_190114402.1"
                     /transl_table=11
                     /translation="MDVLPLVALIAASAAIAGAARRTPVPAPLLLVGVGLIAAYVPGVP
                     EYHLDPHVVLPLILPPLLHTAALESSYLDLRANVRPVALLSVGYVLFATLVVGWLAYLL
                     IPDLPLTAALVLGAVIAPPDAVAATAIARRVGLPSRITTILQGESLVNDATAITAYKVA
                     LAAAVGEGASWGGGIREFLVAAVGGIGVGLILMVPIHWLRTHLKESLLQNTLSLLIPFV
                     AYAAAEQFHASGVLAVVVVALYLGHRSWQVDFETRLQEAAVWKVVGFLLESAVFALIGL
                     QLPVVLGELGEYSVGQAIWYAVAVFVCVVAVRFVWSYPATYLPRVLSARIREREGDMDW
                     RRPLIVSWAGMRGVVSLAIAFSIPLMTDDDEPFPGRNLVLFLTFTTVIGTLVVQGLSLP
                     WLIRVLKVPGRDAQAQTLAEAQAQNAASQAAEARLRELMEDERNRLPGPLEDRLRTVLE
                     RRRNSVWERLGQSNPVTGESADGTYRRLTREAIAAEREVFVRMRDERRIDDELLRTLLR
                     KLDLEEAAAHREIED"
     gene            16704..16964
                     /locus_tag="IE274_RS05360"
                     /old_locus_tag="GCM10010349_10780"
     CDS             16704..16964
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="IE274_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10780"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_190114403.1"
                     /transl_table=11
                     /translation="MNECSHVSALPHPEPAPLSETCLECLAAGSHPVQLRLCLSCGHVG
                     CCDSSPFRHATVHFKETGHPVMRTFEPGENWRWCFVDGSIV"
     misc_feature    complement(17044..17057)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            17209..17622
                     /locus_tag="IE274_RS05365"
                     /old_locus_tag="GCM10010349_10790"
     CDS             17209..17622
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="IE274_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10790"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_030359877.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVNSSVADDKTVSISLYKQRGAGPGPA"
     gene            17619..18785
                     /locus_tag="IE274_RS05370"
                     /old_locus_tag="GCM10010349_10800"
     CDS             17619..18785
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480410.1"
                     /locus_tag="IE274_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10800"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_190114404.1"
                     /transl_table=11
                     /translation="MRNGDGPVRDEERGTRGTHGLPARGRGGTRPASGRGPVEPGPAPG
                     GIPEQQARPHPQDPEQAGQRAAAGTAAAREQAEPTAGDGIDEQSGPGGRQDQAGAARRG
                     SPRASSTGGESPEGRRRVTGGTMSEHEQHSRHDPQDRSGARAKFIELRALQNGSPEYAE
                     LRNQLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATP
                     TVVGEIKRHFRDKGWAVRVPRRLQELRLALTTATAELSQLHGRSPTVHELAEKLAISEE
                     EVLEGLESANAYSTLSLDVPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPR
                     EKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(18883..19335)
                     /locus_tag="IE274_RS05375"
                     /old_locus_tag="GCM10010349_10810"
     CDS             complement(18883..19335)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639613.1"
                     /locus_tag="IE274_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10810"
                     /product="hypothetical protein"
                     /protein_id="WP_190114405.1"
                     /transl_table=11
                     /translation="MSTEPKTTPEAPASGPRPGRLTAAAALAALEGLALVVGGAYMLVM
                     GLAGDPDNPRQATTGGVTLIVLALLPLLAARGLLRLRRWARGPAIITQIMALPVAWQLL
                     QADSVLIPGGIALAAVAVATLVLLIHPATTEALGIGGPGNVQEGSK"
     gene            19438..20406
                     /locus_tag="IE274_RS05380"
                     /old_locus_tag="GCM10010349_10820"
     CDS             19438..20406
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010353615.1"
                     /locus_tag="IE274_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10820"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_190114406.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAAESKDIELVVALGGDGTVNEVVNGLLHNGPSPENLPRLAVVPGGSTNVFARALG
                     LPNDAVEATGALLDALREGSERTVSLGRVSGTPGTDDEAVPSRWFTFAAGLGFDAGVVG
                     RVEQHRERGKRSTHALYVRQVVRQFLGEGDRRHGSITLERAGEEPVTDLVMSIVCNTSP
                     WSYLGNRPLYASPKASFETGLDVLGLKRLSTASVARYGTQLLRSTPDRGPHGKNAVSLH
                     DLTDFTLHSKAPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(20496..20505)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20615..20630)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.59"
                     /tool="antismash"
     misc_feature    complement(20666..20681)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20669..20680
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20725..20982
                     /locus_tag="IE274_RS05385"
                     /old_locus_tag="GCM10010349_10830"
     CDS             20725..20982
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="IE274_RS05385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_10830"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_016639615.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
ORIGIN
        1 agagcgcggc cagcggttcg ctgaacagcc agtgcagggc ggtcgcggtg aggacggcgt
       61 cgtacgagtc gtgcggaagc tgggaggtcc agcccgggtc cttcaggtcg gcggtcacga
      121 aggtgacgcg gtcgtcgtcg gcgaaggtgc cctcggcgat ggcgagcagg gcggggtcga
      181 ggtcgacgcc cgtgctgacg gccttcggga accttttgag gagtctgtcc gtaatacttc
      241 ctgtaccgca cgcgaggtca aggacgcgcg gctcggggcc gacaagggcc tcgaccatgt
      301 ccagcatgac gcggaaccgc tcctcacggt ccggcatgta ccactcctgc tgccgatccc
      361 aactctcctg ccaggcacgc cagtcggtcc cgaaccccgt accgctagcc gtttccgtca
      421 ccggaagacc tccgtcccgt actacgctcg actaatctcg tcgaggtaac acccgcgagc
      481 gaaaagcgac tgttacctcg cacgagaacg aagatagccc gcccccgtaa ggactacaag
      541 tggaactggc ctattactcg gactacgccg tacgcctggt caacaccgag gaaccggctc
      601 gtcacaagga ctcgctgacc tccgtggacg caatccgcga actgttcggc gagaaccagc
      661 aggccgcgcg gcgcgcgacg gactccgacg tgacgcgctt ccgctcggta cgggcgcggc
      721 tgcgcggcgt tttcgaggcg gccgacggcg gggacgagac actggccgtg gacctgctga
      781 actccctgct cctggagttc ccggtgagcc cccagatctc cggccacgac tacagggacg
      841 acgacggccg ccccctgtgg cacatgcacc tggcggacca cccgtcgaac gtgaccgccg
      901 ggtacgcggc gatcgccgcg atgggcctcg ccttccacct cacggagtac ggcgtggacc
      961 ggctcggcct gtgcgaggcg acgccgtgcc gcaacgccta tctggacacc tcgaccaacc
     1021 gctcccggcg ctactgctcg gaccgctgcg cgacgcgtgc gaacgtcgcg gcctaccgcg
     1081 cgcgcaagcg cctggagagc gagcggtcgg cgagcacggg gcgcaccgcc aagaaggtcc
     1141 aggagacgag cgcggccagc gagagctgac gccgcccccg cgcctcgcgc tcctcacgga
     1201 atctgctcag cggccggaac cgcgcacgca cacgtgcgag gaccagctcc tccggcacga
     1261 ctccgtagac cgtgctgtcg ccccccgcgt tgtacggatt gtcgccgagc acccaccagc
     1321 cgccgtcgcg ccgttcgacg gcacgcttga ccaccagcag gtcctgttgc agcggatgac
     1381 gcaggatcac cacgtcaccg gggcgcaccc gggcaccgtg ccgcaccagc atccagtccc
     1441 ccggattcag cgtgggcacc atcgacggcc cgtcgacctc gatcagctgg aacggcacgc
     1501 gtgtctcccg cccgtctgcc gtcgtctccg gcatcagaca acctcccgga cccatcctcc
     1561 accggcctcc cggtccaatc ctccaccgtc tccagtgtga ccctggactt ttgtcctaag
     1621 cccatggggg cactcgcgaa aacaggtctc tcacggagta atgtcccacc tgagaagacg
     1681 atcacgagga aggacagctc aatgctctcc cgcctgtttg cccccaaggt gaaggccagc
     1741 gcacactgcg acctgccctg cggcgtgtac gacccggccc aggcccgcat cgaggcggag
     1801 tcggtcaagg ccgtccagga gaagatggcc gccaacgacg acgcgcacta ccaggctcgc
     1861 gccaccgtca tcaaggagca gcgcgccgag ctcgccaagc accacgtgtc ggtgctctgg
     1921 agcgactact tcaagccccc gcacttcgag aagtacccgg agctgcacac gctggtcaac
     1981 gacaccctca aggccctctc ggccgcgaag gcgtcggcgg acccgaagac cggcgagaag
     2041 gctctcgagc tgatcgccga gatcgaccgc atcttctggg agaccaagaa ggcctgaacc
     2101 gggcccggaa tccggtccgc gcggaccggc ccctcgccca cccgaccgca cccggtccgc
     2161 cggtccgccg tagtcacggc ggccctgacg ggccgggtgc ggtcgtctgt cacgccgcca
     2221 ggacacggcc cccgctctct ccccccggcg tacgcagacg gccgccctcg cccctccccc
     2281 gcccacaaat tcggttgccg ccgcccgcca ccccctgctg cactgaccgt ggcaccaccc
     2341 gcgccgcgcc ccgcgcgccg ccacccgccc cgagtgagcc aggagttccc cgaatgcgcc
     2401 agacgtccat gtcccaccag gaaggaatca acccccaaaa cgaggacatg acgcctagtg
     2461 caatcgcacg cccttcaact cacccagagc cgtcaacaca cccttaacct gggcattctg
     2521 gcgcatatcg acgccggtaa gaccagcctg accgagcggc tgctgcacgc cgccggagtc
     2581 atcgacgaga tcggcagcgt cgacgccggc agcacccaga ccgactccct cgcgctggag
     2641 cggcagcgcg gcatcaccat caagtcggcg gtcgtgtcgt tcgcgatcga cgacgtctcg
     2701 gtcaacctca tcgacacccc cggccacccg gacttcatcg ccgaggtgga gcgggtcctg
     2761 agcgtgctcg acggtgccgt gctcgtcgtg tccgccgtcg agggcgtcca ggcgcagacc
     2821 cgcgtcctga tgcgtacgct gcgcagactc gccatcccca cgctcgtttt cgtcaacaag
     2881 gtggaccgcc gcggcgcgga ccccgagcgc gtactcgccg agctggcccg gaaactgacg
     2941 cccgccatcg ctcccatggg cacggtgcgc gcccccggcg gccacgccgc gcggtacgtc
     3001 ccgtacgccg ccgacgatcc cctcttcacc ggccgcctgg cggagctcct cgccgagcac
     3061 gacgacgcgc tgctgtccgc gtacgtggag gacgaagccg ccgcccttgc gccccgcggg
     3121 ctgcgtgcgg ccctcgcgga ccagacccgg cgggcccggg tccacccggt gttcttcggc
     3181 tcggccatga ccggcaccgg cctggacgcg ctcaccggcg ccgtcaagga gctgctgccc
     3241 gcggcggccg gggcggcgga cggacccgtc gcgggcaccg tcttcaaggt cgaacgcggc
     3301 ccctcgggcg agaaggtggc gtacgcgcgc ctcttctcgg gcacggtgcg cgtacgcgac
     3361 cgggtggcgc tcgccggtcg cgagcccgag caggagcatg ccgacgacag caaggtcacc
     3421 gccgtcagcg tcttcgagca gggcgcggcc gtgcggcgtg acgccgtggc cgccgggcag
     3481 atcgcgaagc tgtgggggct cacccgcgta cgcatcgggg acgtgctcgg cgacgcgcgc
     3541 cacgtacccg aacggcacac caccgcgcac cacttcgccc cgccgaccct cgaaaccgtc
     3601 gtcgcgcccc ggcatgccgc cgaccgggcc gccctgcacg cggcgctgac ccagctcgcc
     3661 gaacaggacc cgctgatcga cctgcggcag gacgcgctgc ggcaggagat ctccgtgtcc
     3721 ctgtacgggg aggtgcagaa ggaggtcatc gaggccacgc tcgccgacga gttcggcgtc
     3781 ggcgtggagt tccgcgagag cacgaccctg tgcgtggagc gggtcgtcgg caccggcgcg
     3841 cacacggagt tcatcgacac cgaccccaat ccgttcctcg ccacggtggg tctgcgggtg
     3901 gagcccgcgc cggccgggaa gggcgtggaa ttccggctgg gggtggaact cggctccatg
     3961 ccttacgcgt tcttcaaggc agtggaggac acggtcaggg agacgctggc acaggggctg
     4021 cacggatggg aggtgcccga ctgcctcgtc acgatgacgc actccgggta ctggccgcgg
     4081 cagagccacg cccacgccgt cttcgacaag agcatgtcca gcacggccgg ggacttccgc
     4141 cagctcaccc cgctcgtcct gatggacgcg ctgcggcggg cggggacgcg ggtgcacgag
     4201 cccatgcacc ggttccggct caccgtgccc gccgacgtgt tcggcacgct gctgtccgct
     4261 ctcggacggc tgcgcgcggt gccgcacgcg ccgacggcac acgggtccac gtacgtcatc
     4321 gacggggtga tccccgccgc gcacgtgcac ggccttgagc aggcattgcc cggactgacg
     4381 cgcggcgagg gcgagttgga gtccgccttc gaccactacg cgccggtgac cgggacgccg
     4441 ccggcgcgcc cgcgcacgga ccacaatccg ctggaccgga aggagtacgt gcagcgggtc
     4501 acgcggcgga cccgggtggg gtgagggtca gtcggcggtg ggaggggtgc cgtcggcggt
     4561 ggaggaggtg ccgtcggcgg tgttggttcc ggcatcggct ccggcatccg tggcggttcc
     4621 cgccccggcg tcggcgcccg cggcgggtcc cgcggacgtg accgccgcga ccgtccgctc
     4681 gtccacgagc tcccgcagcc gctcctggtc cgccaggatg ttgatctcga cgatccggcc
     4741 gtccctgacg gtgaactcgc cgacggagaa cgcccttccg tcgtggacgg cgatctgccc
     4801 caccttgccg ttgaccagcg cgaggtaggt ggtcggcgcc agcgtggaga acgagcgtgc
     4861 cccggcgacc accgcggtcg cgccccgcac cagccgggag aggccctcgg cgccgccgcc
     4921 gtcggcccgc agcaccacgc ccgggtcgag aagttcgagc agcgcgtcga agtcgccctt
     4981 gcgggccgcc gcgaggaagg cctcgacgac ctggcggtgc cgggtgcggt ccgtgtccgg
     5041 ggcgggcgcc gggtccgagc cgcgcacccg gcggcgggcc cggctcgcga gctgccgggt
     5101 cgcggccggg gcccgctcga cgatgggcgc gatgtcctcg aacggcacgg cgaacatgtc
     5161 gtgcagcacg aacgcgagcc gctctgcggg gctcagcgtg tccaggacga cgagcagcgc
     5221 gagccccacc gagtccgcga gcagagcctc ctgctcgggg tcgacggcgt cccggccgcc
     5281 cggcagcggg ctgacctccg ggtcgggcac gtgcgtgtcg gaggcctgga cgtccagggg
     5341 ctgctcgccg cgctgcttgc gcgcccgcag caggtcgagg cagacgcggc cgacgaccgt
     5401 cgtgagccaa ccgcccaggt tctccacgcg ttcgtcgtcg acgcggctga gcttcaacca
     5461 ggtctcctgg acggcgtcct cggcctcgct caaggagccg agcatgcggt acgcgaccgc
     5521 cttcaggcga ggcctgtgct cctcgaagcg ctgtgccaga agatctcttc cgtccatccg
     5581 tcacattcct tcgtcgtgat ccgtcgtagc ggtgacgtac ccgcgacgac ggtgcgccgc
     5641 aggtcggcac ggcaggtgtg gaccagcaga ccacgaagcg gtgcggcgga agcgatcttg
     5701 ccgatgtgac ttggaggaca ttgccatgac gtacgtcgac gccccggtgc gggcggaccg
     5761 cgcggtgcga gcgggcgaca cgggatgggg tgtggtgcgg gcgggcgaca cgggacgggg
     5821 tgtggtgcgg gcgggcgaca ctgggtgggg tgcggtgccg ggaatgccgc ggccacggat
     5881 gtccgcccgc tgcccacgcc cccggtgcgg gcaccctcag cccaacacgg gccccagcgc
     5941 cgtctccagg tcgtccggcc cccggtacag cacgcccgtc atgcccagcg cgaccgccgc
     6001 gtccacgttc tcctcgcggt cgtccacgaa caggcagcgg gtgaccgcga cacccagacg
     6061 ctcggcggcg acttcgtaga tgcggcggtc gggcttcacc acgccgagta ccgcgctgga
     6121 gaccacgtcg tccacgaggg tgttgaggcc gagcagcgcc aggtcgtcgt ccagccaggg
     6181 ggtggcgttg gtgacgatcg acacgcgtac gtgcgcgcgg gcccgccgca gcaggccgac
     6241 gaccgtctgg tcggcccaga acttggagtc ggccagggcg atgccgagtt cacgcccgtg
     6301 cgccggggcg agcccgtgcc cgcgcgcgag tccggccgcg atcgagtcgg cccactccga
     6361 cttgccgatc cgcccgagca tgagcggcag atcggtctcc ggcgcgaacg cgacctcggc
     6421 ggtggcacct tcgggcagcc cggcggcgcg ttcgagctcg gcgacgtcgg acatgtcgta
     6481 gaagcggatg acgccgtcga ggtcggtgag gacgacgtcg aacgggaggt gagagttcct
     6541 gtcggacggg aggtgagacg tcctgtcagg cgggaggtga gactgtccgc cgaacgggag
     6601 ttgaggcttt ccaccgtgcc ggttcatcca ccggctccca gcacgctccg cacggtcgac
     6661 cgcacccttt cctggtcggc gcgcacggct tcgtacgcgg atctgtgccg ggatatgtcg
     6721 cgccgctgcc gctcggccgc gacggtccgc cacaccccgg cggtgttgtg ctcgcgcttg
     6781 cactcgatgt cggcgacggc cgtgtcccgc tcgcgccggg tgcgccgggt gtcgccgtcg
     6841 ctgccgcggt gccacgcctt gtcgcggaag gcggcctccg ggctcgcgta ccgcttgaag
     6901 cccttgtcga cgacgcagtc cgcccaggtg tcgagggcgc gccgcatccg tgggtccttg
     6961 gcgacggcct tgtcgatcgc ggcgcgtcgg ccgacgacgt acgccgtcat gcgggtctcg
     7021 tccttgacgt ccgccaccac gcgccgcgcg cccacctgga cgcagccggc tttggggacc
     7081 tcatgtccgc cgtcctcggg ggccttgcgc ccgcctgccc cggaggcacg ccccgcggcc
     7141 gagtcgtcgc ctggtggcat gccgatgccg aacagcatgg tgttctcgtc cggcgtgatc
     7201 aggcgtccct tcggcgcgcg cttcttctcg aacgccttga gcgcctcgcg gtcgaggccg
     7261 tagccgcggc tgcgggcgcc gccgaggtcc aggctgccgt acagggtcgt cgagatggcc
     7321 accgctgtcc gggagctgga catgtcgatg ccctggtcgc gccagcgcag ggggaagtcg
     7381 gggaagccgt gggaccgcat gcaccgctgg gtgaagcggg cggacgcgtc ctcccggcgt
     7441 tcgtggtcac gcgcactgaa ctcgtaccgc tccaggggca gtccggtcag gtccttctcg
     7501 tcgtcgacct caggcactcc cgagccacgc gccgcgcccc cgccggatcc gcccgtcgtg
     7561 gacccgcacc ccgccagtgc cgccagcgcc accacggcca ccgcgacggc cacgcggcgc
     7621 gacccccgca ccccccacgt caccttcatg cgcagaaccc taaccgcgcc cactgacagt
     7681 cgagggtccc gctcccccgc cccttccgga cgcagccgtt ccagtcagct ccctagaggc
     7741 gaggactccg aggtgtcacg gaggatcggg ctcggggcgg ggcttcggct ccgcttgcgc
     7801 tcccgtccgg gaggcgactt ccggtacggc ctggggagcg gtcgcagtcg cgccggactc
     7861 caggtcgatc tccggcgcgg gctccgccgc ggccttggtg ccggcctccg gggcgtgcct
     7921 cggcaggtgc ccgggcttgt gcttgctctt gtagccgcgt cccgcccgcg acttctcgtc
     7981 cggttcgtcg gcgacgcacg cgtcgcactc cgggttgtgg caaggagccg gagcccacac
     8041 cgggacgtac gccccgagca ccttgcgccg cttgatggcc gtaccgacgg gccgtccgca
     8101 gtgcttgcac acggggtcgc tctgcggacg ggggccggac cggcgtccat cgctgcccat
     8161 gacctcaggg tagggcgatt ccccgaggtc ggacagccca gcggtcagtc cttcccgcgc
     8221 ttgcgggagt acgtgcggac gacgacgccg ttgccgaaga tccgggacga ggccagttcg
     8281 aactcgctga ccgcggactc cacgcccccg aacatcggca tgcccgagcc gagcagcacc
     8341 ggataggtct tgaggaccag ctcgtcgacc tcgtcgatca gctgaccggc gacctgggca
     8401 ccgccgcaca gccagatgcc gagctcgccg tcctcggcct tgagcgcgcg gaccttgccg
     8461 agcaggtcgt cggtgatgat ctcgacgttc gggctgggcg actccccgat gctgtgcgag
     8521 gcgacgtact cacgcaggtg cccgtacggg ctcggctcgc cctcgtccag gccgagctga
     8581 tagctgcccc tgccctggat gacggtgtcg aacttctcgt tcggcacgcc gtcgccgaag
     8641 ccgaggatct tgcgtccggt ggcggagacg gtctccgggt actcggtctt gaggaacccc
     8701 aggaactcct cgtccacgaa cggcatgaag gagttggcgt cgcccgtcgg gtcaccgatg
     8761 aacccgtcga tcgagacggc gacgaagtag gtgagctttc gcaagctgat tctctttccg
     8821 cagatgacag tggggttgag acgagggtga ccgggccacc cccgcttcga acaactgcat
     8881 ttatagtgct tcacccgcag tggtttcaag tgtttctctg aaacagccac aaaaaatcgg
     8941 ccccgggggc ctggcgccct gcgccacagc cgttcccgag gccgatccgt gagcccgccc
     9001 gcaggcctcc atgagcccgc ccgcaggcct gtctctggcc gccgatgccg ccgaagtctc
     9061 cgcgtcacac cgcccgcggc tcgcgccaca tgggccacat ccgcggcccg tccggcaggt
     9121 ccagcgggct gccgaggtcg gtgaagccga gccgcagata cagctcccgc ccgcgcgggc
     9181 tgctcgcctc caagtaggcg tgcagcccct cacggtcgca ccgcgcgagc accggggcga
     9241 cgagcgccga tccgatgccc tcgccctgcc gctccggctt caccccgatc atgtgcaggt
     9301 actggtgcgg ccggtcggac gggtggatct ccgacgccaa ccggccgatc gtctcgacgc
     9361 gttcgttgtc cgggtcgacg gcctggcgca gttgcacggg cccgtcggcg gcgtccccgg
     9421 gcggcgggcc cgcgggcacc gaccaccaca gggcgacacc cgagccgtcc tcggcgaggt
     9481 ccacgtaccc ttcggcgaag gccatgtcga ggaaggcgcc catgagcgcg ccgtgccgcc
     9541 tccgccgccg ctgctcgtcc gggaacaccc aactgctcac cggatcccgc atgaacgcct
     9601 cgtcgagcag cccgaccacc tccgcccggt cgctctcccc ggctctccgg atcggcacac
     9661 ccacgacgtc cccctcgtcc ttgcctcgac gacccgcgac ctcaggcccg gccccgcact
     9721 gccggtcgca gcctaagtga tcgtttcgta cgcgacgacg gctccgtaga cagctatttc
     9781 agcggtggcc ggggcgttgt gggttcggtg cccccggcgt tctccgaccc tccggccgac
     9841 ccgcccgtca gcgcatggcg agccggtcgg cgtacggccg atgaccgcac gccgaccggc
     9901 agcgccccac cccctcccgc accaccggct gccccaagac gaccgccggc tccccggcgg
     9961 agcgccccct ctcacgcccc gccgggaagc cctcggacgg tcagtgcgac cggcgtgtga
    10021 cgaactccgc gagcgccagc aggccacccg cacgctccgg gtcgggcacc gcccgggcca
    10081 gttccccgag cgcccgcgac atccggtccg ccgcgtggag ctgcgcccag tcccggcccc
    10141 cggcgccctc cacggcgcgg gccatccggt ccaggtcgcc ctggtccgac cctcggccgt
    10201 acagcccggc gagtgccgcg ccttcgggcg tgccggaggc cagcgcggcg accaccggca
    10261 gcgacttcct gcgggcggcg aggtccgcgc gcgcgggctt gccggtgcgc gtgggatccc
    10321 cccagatgcc gatcacgtca tcgatgagct ggaaagcgag cccggcctgc cgcccgaacc
    10381 cgtcaagcgc ctccacctcg tcggcccccg cccccgcgta caccgcgccg atcgcgcagg
    10441 cgcacccgag gagcgcgccg gtcttggcct cggccgcggc caggcactcc gtgagcgaga
    10501 cctcgtccgg gccccggctc tccagggcgc ggtcggcctg ctgcccggcg cagagctcga
    10561 cgacgcacgc ggccaggcgg gcggccgccg ccggggcccc cgggtggggg tcctcggcga
    10621 gcagccgctg tgccagtgcc tgcagggcgt ccccggcgag gatcgcgtcg gagtcgccga
    10681 acacggtcca cgcggtgggg cggtgcctac gagtcgcgtc gcggtccatg acgtcgtcgt
    10741 ggagcagcgt gaagttgtgc gtcagctcca cggctgcggc cgccctgaca gcgctcagcg
    10801 ggtccccgcc gagggcccgc accgcggcca ggacgagggc gggcctgatg gccttgccca
    10861 cgttcccggc cgcgggcgtc ccgtcggcgt gttcccatcc gaagtggtac agcgcgatgc
    10921 ggcgcaacga accgggcagc gactcgaccg ccgcgcgcag ctccgggtcg acgcacagcc
    10981 gcgccgacgt caggatctcc gcggcctcgt acccctcccc gaggacctgc ccgcgggggc
    11041 ggggcgcgca ttccgtcatg tccgtggtgt ccgtcatgga ctcactccgg cggggcggcg
    11101 gacggtggcg gatcctggac ctgcgggcgc gtacgccaga ggtctacccg tctgcgttcc
    11161 catgggcacg ggcgacggcc cgccacccgc gacgacgggg cgtcgcctca cctccaccgg
    11221 ccgatctcga cgttctccag gatgccgagg gcgtccggta ccaggacggc cgcggagtag
    11281 tacgtcgaca ccaggtagga gatgatcgcc tggtcgctga tgcccatgaa gcggacggac
    11341 aggctcggct cgatctcgtc cgggatgccc gcctggtgca gtccgacgac gccctgctcg
    11401 tcctcgcccg tacgcatgca gatgatcgag gacgtccgct cctcggtcac cgggatcttg
    11461 ttgcacggga agatcggcac gccgcgccag gtggggatgc ggttgccgga cacctcgatg
    11521 gtctcgggga ccagcccgcg cttgttgcac tcgcggccga acgcggcgat cgcgcgcggg
    11581 tgggcgagga acagcttcga tccgcgcctg cgggtgagca gttcgtccat gtcgtcgggg
    11641 ctcggcacgc cgtcgtgcgg ctgcaggcgc tggtcgtact cgcagttgtt gagcagtccg
    11701 aactctcggt tgttgatgag ctcgtgctcc tggcgctcct tcagggcctc cacggtcagc
    11761 cgcagttgct gctcggtctg gttcatcggc tggttgtaga ggtcggccac gcgcgtgtgg
    11821 atgcgcagca cggtctgggc gacgctcagt tcgtactcac gcggccgcga ctcgtagtcc
    11881 acataggtgc ccggcaggac agcttcgccc acgtggcccg aggagaggtc gatggcggcc
    11941 tctccgtagt tgttggtgcg ctggacgggg atggcacgca gccggtcgag gtgggcgcgc
    12001 aggctctcgg agcgctccgc gacctgctcc aggtcctggc gcgggagcgt gaggaccgtg
    12061 caggccgtca ccgcgcgcac cgtgtactcc cagatggtct ccgggtcgat gagggcctgg
    12121 tcgccgaagt acgcgccgtc ggcgagcgtg ccgaggacgg tgtcgtcgcc gtagggaccc
    12181 gtgccgatct tctctgcgcg gccgtgggcg aggaggaaca cctcgtccgc ctggttcccg
    12241 aacgacgtga gcaccccgcc ggcctcgaac tcgcgctgct ggcagcggcg cgccagttcg
    12301 ctgagcacct cctggtcctc gaagtcccgc aggaccggca gttccccgag ctcggcaggg
    12361 atcacctcga cgcggtctcc cgtcttgacg aacgtgaccc ggccgtcccc taccgagtag
    12421 ctcgtcctgc ggttcacgcg gtacgtaccg ccctgcacct gcacccaggg cagcatccgc
    12481 agcagccagc gggagctgat ctcctgcatc tgcggcgcgg acttggtggt ggtggccaga
    12541 ttccgcgcgg cggatgtgcc gagactctgc tgcggctggt cctgctccga acggatctct
    12601 tcgcctaccg acatggacaa tgccctccca atcatgcgct gacctggctc gcaacccttc
    12661 cagcacggtg agtacgggcg ccattacaca aacgagcggg aatggatcga ggtggaccgg
    12721 gcacgttgcc gtttaccagg cccgatccct cgtacgttcg tccaagggcc gctgcggcgc
    12781 ggctccgcgc ggccgcagaa gcggaatatc agccgccaag gcgaatggtt tcagccaacc
    12841 cctggcgtgc gggccgaccg gctgacgcgg gcgcccaccg ggtacggcga cggggcgaag
    12901 gggaactcca agatccgtgc gttcgttcac aagagcgagc gcagcgtacg caccatcagc
    12961 accgaaccat cgggagaagc gacatggcag gcttcctgga ccgcgccaga gaacaggtgc
    13021 agcagggtct caaccagggc aagcagaagc tggacgacgt gcaggcgcag cgggcgggca
    13081 acgacctgct caagcagctc ggcgcggcgt actacgcgga gcgacgcggc agcggcaccc
    13141 cggacgccac ccagcaggca ctcgccgccc tcgaggcgca catcgcgacc cacggcgacg
    13201 gcttcctgcg cgcctgacac acccccaccg accagccctc cggctgaccg gatcgactcg
    13261 cacggcgccc gaacagatgg ttcgggcgcc ggcggttccg gtacaagcag cgtacgaggc
    13321 ggatcgcgac cagcgaccgt cgcgcccgca aaggaggtgg tcatggcccc acccatgtcc
    13381 gcgaacaggt tcctggactt gcttcgggac gaaggcgtca cggtcgtcga agtcggcaac
    13441 tggcgcgagc acaaccgcaa tcatgtgggc ccctggggcc cggtgcacgg cgtgatgatc
    13501 caccacaccg tcacctccgg cagcgagctg accgtgcgcc tgtgccgcga cggtcactcc
    13561 accctgcccg gcccgctctg ccacggcgtc atcaccaagg acggccgcgt ccacctcgtc
    13621 ggctacggcc gcgccaacca cgccggcctc ggcgacgacg acgtgctgcg agccgtcatc
    13681 gcggagaagc ggctcccgcc ggacaacgag gccaacaccg acggcaaccg gcacttctac
    13741 ggcttcgagt gcgagaacct gggtgacggc gaggacccct ggaccgacga gcagttggac
    13801 gccatcgaaa gggtctcggc cgccgtctgc cgtcaccacg gctggaccga gcgctccgtc
    13861 atcggccacc tggagtggca gcccggcaag atcgacccca aggggttcac gatggacgcg
    13921 atgcgggacc ggatcggaga gcggctgaag ggctgaacca gccaccacgg ccggtgtcga
    13981 ccggtctcag ccggttatcc ccccatccac gcctccacca gcccagaccg cccaccacga
    14041 gggagaatgg cggggtgccc gccaccccgc ccacctccgc cctgcgaccc cggctcccca
    14101 ccccgctgca gccggtcatg gacccccgtt tcgaggcccg cgacgtccgc ctgctcctca
    14161 agcgcgacga cctgatacac ccggacctgc ccggcaacaa gtaccgcaag ctcgccctca
    14221 acctggagca ggcgcgggcg gcgggccacc gcacactgct caccttcggc ggcgcctact
    14281 ccaaccacct gcgggccacc gccgcggcgg gccgcctgct gggcttcgcc acggtcggcg
    14341 tggtccgcgg cgacgaactg gccgaccgcc ccctgaacac gtccctcgcc cagtgcgcgg
    14401 cggacggcat gcggctgcac ttcgtcgaca gatcgatgta ccggcagaag gcggatcccg
    14461 cggtcctgac cgggctccag cgggcgacgg ccgccgagga cgcgtatgtc atccccgaag
    14521 gcggcagcaa cgcgctcgcc gtccagggct gcgtggccct cggcgcggag ctgcgcggcc
    14581 gcaccgacgt cgcggccgtc gcctgcggca ccggcggcac cctcgcgggc ctggcagcgg
    14641 gcctcggccc cggccagcgc gcgctcggca tacccgtcct gaagggcggc ttcctggggc
    14701 ctgagatagc gggcctgcag cgcgccgcct tcggcgtccc cggcaccaac tggtccctcg
    14761 acgaccgctt ccactgcggc ggctacgctc gcaccaccgc cgaactcacc gccttcgccg
    14821 acgacttcga gcagcgacac ggggtccccg tagagcgcgt ctacgtggcc aagctgctgt
    14881 acgcgctgac cgtgctctcc gaagagggcg ctttcgcccc ggggacgacg gttacggcgg
    14941 tcatcaccgg cacgccatcc gcctgacctg cccgcggcct cccgcccccc ccggccccct
    15001 tgctcgcccg gtccgcccgg cccactcagc cccggcccgc catccagcgc cccccggctc
    15061 agtcctcgat ctcccggtgg gccgccgcct cctccaggtc cagcttgcgc agcagcgtcc
    15121 gcaacagctc gtcgtcgatg cgccgctcgt cccgcatccg tacgaacacc tcgcgctccg
    15181 cggcgatcgc ctcgcgcgtg agcctgcggt aggtcccgtc cgcggactcg cccgtgacgg
    15241 ggttggactg gccgagccgc tcccacaccg agttgcggcg ccgttcgaga acggtgcgca
    15301 gacggtcctc aaggggccct ggcagccggt tccgctcgtc ctccatcagc tcccgcagcc
    15361 gggcctccgc ggcctgcgag gcggcgttct gcgcctgcgc ctcggccagc gtctgcgcct
    15421 gtgcgtcccg ccctggcacc ttcaggaccc ggatcagcca cggcagtgac agcccctgga
    15481 ccaccagcgt cccgatgacg gtcgtgaagg tcaggaagag cacgaggttg cggcccggga
    15541 acggctcgtc gtcgtccgtc atcaacggaa tggagaacgc gatcgccagg gacaccacgc
    15601 cgcgcatccc cgcccagctc acgatcagcg gccgccgcca gtccatgtcg ccctcgcgct
    15661 cgcggatccg cgccgacagc acgcgcggca gataggtcgc cggatacgac cacacgaagc
    15721 gcaccgccac gacgcacacg aacaccgcga cggcgtacca gatcgcctgc ccgacgctgt
    15781 actccccgag ttccccgagc accacgggca gctgcaagcc gatgagcgcg aagaccgccg
    15841 actccaggag gaagcccacg accttccaga ccgcggcctc ctggagccgc gtctcgaagt
    15901 cgacctgcca ggagcggtgc cccaagtaga gggccaccac gaccacggcg agcactccgg
    15961 aagcgtggaa ctgctcggcg gcggcgtacg cgacgaaggg gatgaggagc gacagcgtgt
    16021 tctgcagcag cgactccttc aggtgggtgc gcagccagtg gatcggcacc atcaggatca
    16081 gccccacccc gatcccgccg acagcggcca ccaggaactc ccggatgccg ccgccccagc
    16141 tcgcgccctc gccgacggcc gccgcgagcg ccaccttgta ggcggtgatc gcggtggcgt
    16201 cgttcaccag ggactcgccc tggaggatcg tcgtgatgcg cgagggcagt cccacgcggc
    16261 gcgcgatggc ggtggccgcc acggcgtccg gcggcgcgat caccgccccc aggacgagcg
    16321 cggcggtcag ggggagatcg gggatcagca gatatgcgag ccagccgacg accagggtcg
    16381 cgaacagaac gtaaccgacg gacaggagcg cgacgggccg cacattggct ctcaggtcca
    16441 gatacgagct ctccagggcg gccgtgtgca gcagcggcgg caggatcagc ggcagcacca
    16501 cgtgcgggtc gaggtggtac tccggcacgc cggggacgta cgcggcgatc aggcccacgc
    16561 ccaccaggag cagcggtgcg gggaccgggg tccggcgcgc ggcgcccgcg atcgcggcac
    16621 tcgcggcaat cagcgccacc aggggcagta cgtccatcgg caaggccctc cgcggtccgc
    16681 tctcccgtcg taacctggcc atcatgaacg agtgctcgca cgtcagcgcg ctgccccacc
    16741 ccgaaccggc acccttgagc gaaacgtgcc tggagtgcct cgcggccggc agtcaccccg
    16801 tgcagctacg gctgtgcctg agctgcgggc acgtgggctg ctgcgactcg tcgccgttcc
    16861 ggcacgcgac ggtgcacttc aaggagaccg ggcatccggt gatgcggacc ttcgagcccg
    16921 gcgagaactg gcgttggtgc tttgtcgacg gttcgatcgt ctgaggcctg ggtacgtcaa
    16981 cccgacgctc gctctttcca attgggtccg cgaaacccct agccactgtc cgtacccgta
    17041 ggcttactat gagtgacagc aacggggtgg ggccccggga cacggaactg ggcagcgcgg
    17101 tagcgtcacc gctgaaaaac gtggtgcgtc acccgtgtga cgcagtccgg accgccgcgg
    17161 cgcgacggcc ggagccccga aagtgcttgt accaccttgg aggtgagggt gtcccagatc
    17221 gcaggcgagc ccgggaatca ggacttcgtg gaggtccgcc ttccggctgc gggtgcctac
    17281 ctgtcggtgc tgcgtacggc cacggccggc ctcgcggcgc gcttggactt caccctggac
    17341 gagatcgagg acctccgcat cgctgtcgac gaggcgtgcg cgatcctgct ccagcaggcc
    17401 gtgcccggtt ccgtgctcag ctgcgtcttc cggctcgtcg acgactccct ggaggtgacc
    17461 gtctcggcgc ccaccacgga cggccgcgcc ccggagcgcg acaccttcgc atggactgtc
    17521 ctttcggccc tcgcgggcaa ggtcaactcc tcggtagccg acgacaaaac cgtttcgatc
    17581 agcctctaca aacagcgcgg cgcgggaccc gggccggcgt gaggaacggg gacgggccgg
    17641 tgcgggacga agagcgcggc acacgtggca cacacggtct gcccgcccgc ggcaggggcg
    17701 gcacacgtcc ggcctccggg cgcggtccgg tggagccggg gcctgccccg ggcggcatcc
    17761 ccgagcagca ggccaggccg caccctcagg acccggagca ggcgggccag cgcgcggcgg
    17821 ccgggacggc cgccgcgcga gagcaggcag agccgaccgc cggggacggg atcgacgagc
    17881 agtccggccc gggcgggcga caggaccaag caggcgccgc acgcaggggg tcgccccggg
    17941 cgtccagcac tgggggcgag tccccagaag ggcggcggcg ggtgacgggc gggacgatga
    18001 gcgagcacga gcagcacagc cggcacgatc cacaggaccg cagcggcgcg cgggcgaagt
    18061 tcatcgagct gcgcgccctg cagaacggca gcccggagta cgcggagctg cgcaatcagc
    18121 tggtccgcat gcacctgccg ctcgtggagc acctggcccg ccgcttccgc aaccgcggcg
    18181 agcccctgga cgacctgacc caggtcgcca cgatcggcct catcaagtcg gtggaccggt
    18241 tcgacccgga ccgcggcgtc gagttctcca cgtacgccac cccgacggtc gtcggtgaga
    18301 tcaagcgcca cttccgtgac aagggctggg cggtccgcgt gccgcggcgc ctgcaggagc
    18361 tgcgcctggc gctgacgacg gccacggccg agctgtcgca gttgcacggc cgttccccga
    18421 ccgtgcacga gctggccgag aaactggcga tctccgaaga ggaggtcctg gagggcctgg
    18481 agtcggcgaa cgcgtactcc acgctgtccc tcgacgtccc tgacaccgac gacgagtcac
    18541 cggccgtcgc ggacaccctc ggcgccgagg acgaggccct ggagggcgtc gagtaccgcg
    18601 agtccctcaa gccgctcctc gaggatctgc cgccgcgcga gaagcgcatc ctgctgctgc
    18661 ggttcttcgg gaacatgacg cagtcgcaga tcgcccagga ggtcggcatc tcccagatgc
    18721 acgtctcccg gctgctcgca cgcaccctgg cgcaactgcg cgagaagctc ctcgtggagg
    18781 agtgaggggg ccgcacggcc gcacagcgac gccactgggg gcggcgagga tgtcctcgcc
    18841 gcccccagtg gcgtccgcag accgcgcgta ccggtcgtac ggctacttgc tgccctcttg
    18901 tacgttgccg ggcccgccga tgccgagcgc ctcggtggtg gcggggtgga tcagcagcac
    18961 cagcgtcgcg accgcgaccg cggcgagcgc gatgccgccg gggatcagca cgctgtcggc
    19021 ctggaggagc tgccaggcca cgggcagcgc catgatctgc gtgatgatcg cgggcccgcg
    19081 cgcccagcgg cgcagccgca gcaggccgcg ggcggcgagc agcggcagca gcgcgaggac
    19141 gatcagcgtg acgccgcccg tcgtcgcctg gcgcgggttg tcggggtcgc ccgcgagccc
    19201 catgacgagc atgtaggcac cgccgacgac gagggccagg ccctccagcg cggcgagcgc
    19261 cgcggcggcc gtgaggcgcc cggggcgggg gcccgacgcg ggggcttcgg gggtggtctt
    19321 cggctcagtg ctcacgcatc gagggtagcc ctgggcgccc ggggaccggc acatcggtgc
    19381 ggttcaggcc agacctcggt ctgggccggg taaagaccgc taggtagtct gctgcgcatg
    19441 cgtgcacttc tcgtggtcaa cccggcggct actaccacca gtgcgcgcac acgtgacgta
    19501 ctgatccatg cgctcgcgag cgagatgaag ctggaagcgg tgactacgga gtaccgcggt
    19561 cacgcccgcg acctgggtcg gcaggcggcg gagagcaagg acatcgagct ggtcgtggcc
    19621 ctcggcggcg acggtacggt caacgaggtc gtcaacggtc tgctgcacaa cggcccctct
    19681 ccggagaacc tgccgcgcct cgccgtcgtc cccgggggct cgacgaatgt cttcgcgcgc
    19741 gcgctgggtc tgccgaacga cgccgtggag gcgaccggcg cccttctgga cgcgttgcgt
    19801 gaaggaagtg aacgcacagt gagcctcggc cgggtctccg ggaccccggg gacggacgat
    19861 gaagcggtgc cgtcgcgctg gttcacgttc gctgccgggc tgggattcga cgcgggagtg
    19921 gtcggtcggg tcgaacagca ccgggagcgc ggcaagcgtt cgacgcacgc tctttacgtg
    19981 cgccaggtgg tacgccagtt cctcggcgag ggcgaccgca ggcacggctc gatcacgctg
    20041 gagcgggccg gcgaggagcc ggtgaccgac ctcgtgatgt ccatagtctg caacacgtcc
    20101 ccctggtcct acctgggcaa tcgtcctctg tacgcgtccc cgaaggcgtc cttcgaaacg
    20161 ggcctggacg tgctgggact caagcgtctt tcgaccgctt cggtggcccg ctacggcacc
    20221 cagttgctgc ggtcgacacc cgatcgcggg ccccatggga agaacgccgt ctcgctgcac
    20281 gacctgacgg acttcacctt gcattcgaag gcacccctcc ccctccagat ggacggtgac
    20341 cacctggggc tgcggacgag cgtgacgttc acaggcgtac gccgtgcact gcgtgtgatt
    20401 gtgtgagtgg aagggcctaa agtcctttca ctcgaacgtt taggccaggc tccaccccat
    20461 ggaagtacgg ctgtgactca gtcgacaccg aggaatcaaa aaaaactttc ctgaaggggt
    20521 tgtatccgcc gccgaggttt gcgaatctct acatggcgat cgggacggcc cgcaacatcg
    20581 gcctccacag gtagccagaa cccctcctct cactacaggt ccacaccagg caactgggag
    20641 tcgacccttc ccgtgcgggg ggattcgtga aagcgttcac attcacaagc aatcttcatg
    20701 taagaccaag gagaggtagc agccatggac tggcgtcaca acgccgtttg ccgcgaggaa
    20761 gaccccgagc tgttcttccc catcggcaac accggtcctg cgctgctgca gatcgaggaa
    20821 gccaaggccg tctgccgtcg ctgccccgtc atggagcagt gcctgcagtg ggcgctcgag
    20881 tccggccagg actccggcgt ctggggtggc ctcagcgagg acgagcgccg cgcgatgaag
    20941 cgccgcgccg cccgcaaccg ggcgcgccag gccagcgcct gacgcccacg ccccttacga
    21001 gccttagctt ggcggcgcgt gtgcctgacg gcattactcc gtagacagcg cgtacgcaac
    21061 ccccgccccc gagccgc
//
