LOCUS       NZ_BMVR01000002        21095 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000002
VERSION     NZ_BMVR01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 777077)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 166850
            Orig. end                         :: 187945
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21095
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21095
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21095
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11095](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11095
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(421..1860)
                     /locus_tag="IE274_RS04535"
                     /old_locus_tag="GCM10010349_09130"
     CDS             complement(421..1860)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130218.1"
                     /locus_tag="IE274_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09130"
                     /product="cation:dicarboxylate symporter family
                     transporter"
                     /protein_id="WP_229909217.1"
                     /transl_table=11
                     /translation="MAEGQTAVDTAGTGAPPAKRDRTHYLYIAVIVAVLIGIAVGFIAP
                     DFAKELKPIGTGFVNLIKMMISPIIFCTIVLGVGSVRQAAKVGKVGGLALAYFMAMSVV
                     ALAIGLIVGNILHPGDGMDLTSSDKEAGHTAADEADKGLVDFALGIIPKTMVSAFTEGE
                     VLQTLLVALLVGFALQAMGKTGEPVLRGVQHIQKLVFRILGMIMWAAPIGAFGAMAAVI
                     GETGTDALKALATIMIGFYITCALFVLVVLGTLLRLATGVNLFKLLKYLGREFLLILST
                     SSSESALPRLIAKMEHLGVSRPVVGITVPTGYSFNLDGTMIYLTMASLFIADAMDQPLG
                     IGEQISLLLFMMIASKGAAGVSGSGIAVLASGLQSHKPALVDGVGLIIGVDRFMSEARA
                     LTNFAGNAVATLLIGTWTKEVDRERVAAVLDGRIPFDERTLLDDDHGDVGPSLEKKPAS
                     EAEDEVPAGRAAADEAAAVKV"
     misc_feature    complement(1964..1979)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            2027..3703
                     /locus_tag="IE274_RS04540"
                     /old_locus_tag="GCM10010349_09140"
     CDS             2027..3703
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925322.1"
                     /locus_tag="IE274_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09140"
                     /product="sensor histidine kinase"
                     /protein_id="WP_229909219.1"
                     /transl_table=11
                     /translation="MPQVPRPPHPPRRPRGPRSLAGQLFAMQVVLVAVVVAGCALFTYL
                     SDRNQAEEAALRQATAAARAVADSPSVREAIRGEDPSRRLQPYATDVQLHTGVDFVTIM
                     DPRGIRWTHPDPDRIGERFLGHTAEALRGQTFTEIYTGTLGPSARVVTPVFDGGDDRRG
                     EHGRIVGLVSAGITIDAISEKARGQLLALLGVAVAALALGAVGTYVINARLRRSTHGMN
                     AGELSRMHDYHEAALHAVREGLLMLDGRRRVALINDGARELLGAPEGVVGRYVTDLGLP
                     APLTGALLDTRPRVDEVHLTADRVLVVNTSPVSGGDRKGTVVTLRDHTELQALAGELSS
                     ERGFTRALRSQAHEAANRLHTVVSLIELGRADEAVEFATAELELAQALTDQVVAAVNEP
                     VLAALLLGKAAQANEHGVELVVSADTSVDDGMLPTGLPPRDLVTILGNLIDNAVDAAQG
                     SPAARVTVTVRAESGGLLLRVTDTGPGVDPSQRESVFQHGWSTKAPSGRGLGLSLVHQT
                     VTRHAGTLTLTEPEEGGAEFTASLPLEPARVGVRTDGKAAR"
     gene            3700..4389
                     /locus_tag="IE274_RS04545"
                     /old_locus_tag="GCM10010349_09150"
     CDS             3700..4389
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641335.1"
                     /locus_tag="IE274_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09150"
                     /product="response regulator"
                     /protein_id="WP_190114267.1"
                     /transl_table=11
                     /translation="MTDPQPIRVLVVEDDPVAADAHVLYVNRVPGFEATATAHTAAEAR
                     RALDRAPVDLILLDLNLPDGHGLALARTLRAAGHRADVIAVTSARDLAVVREGVSLGVV
                     QYVLKPFTFATLRDRLTRYAEFRNAAGEATGQDEVDRALAALRAPAPAALPKGLSGPTL
                     EKVTRTLQDAAPDGLTAAATADTTGLSRITARRYLEHLVTTGRAARSPQYGHVGRPELI
                     YRWLPPA"
     misc_feature    4501..4514
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            4603..5967
                     /locus_tag="IE274_RS04550"
                     /old_locus_tag="GCM10010349_09160"
     CDS             4603..5967
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984250.1"
                     /locus_tag="IE274_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09160"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_190114268.1"
                     /transl_table=11
                     /translation="MPVRPTAPAPLLLAAVLAASTLTACGGGSGDDPDTVKVSYKQSMD
                     NKIRVMDDYLESMKKQFEKANPGKKVKLVPIKAPDAEYYTKVQQMLRSPKTAPDLVYED
                     TFLINSDITSGYLKPLDPYLDKWKEWPKFIDTAKAAAKAEDGKTYGVPDGTDTRGLWFD
                     KDIFKKAGLPANWQPKNWDEILDAARTIKEKVPDVVPLNVYTGKPGGETSSMQGMEMLL
                     YGTGENPLYDPKAKKWVVGGQGFKDSLKFVETVYKEKLGPDVEDALDPNMATRVRGEFL
                     PEGKLGINLDGSWLPQDWLPGSGHEWPQWSKELGLAAMPTQHGQAPGKVSMSGGWTWAI
                     PSKADNADLAFKFIETMQTKENAKKWYIANSGISVREDVAKDPAYVQAQPGIKFFTDLV
                     ASTHYRPAFPAYPKVSTAMQEAMEQVTTGDGSVDKAASGYDDEVGSATDGKVIEK"
     gene            6042..6848
                     /locus_tag="IE274_RS04555"
                     /old_locus_tag="GCM10010349_09170"
     CDS             6042..6848
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060793.1"
                     /locus_tag="IE274_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09170"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_190114726.1"
                     /transl_table=11
                     /translation="MALFLAGPIGYCAYIAFTDLQLTGQAHESFVGLENFRTAFDDEDF
                     INAVWLTLVFTFLSSIVGQNTLGLALAALMQRASKTVRTITGAVVVTAWVLPEVVAGFL
                     LYAFFRRDGTLNAVLDFLHLPSQNWLYTLPILAVSFANVWRGTAFSMLVYSAALNEIPK
                     EITEAAEVDGASGWRRMWHITLPMIRRSIGTNLMLNTLQTLSVFGLIWVMTRGGPGNRS
                     QTLPLFMYEQAFQKSMIGYGTAVALLLLLVGSLFSLIYMRLLRTEV"
     gene            6849..7691
                     /locus_tag="IE274_RS04560"
                     /old_locus_tag="GCM10010349_09180"
     CDS             6849..7691
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122720.1"
                     /locus_tag="IE274_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09180"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_190114269.1"
                     /transl_table=11
                     /translation="MSSTPSARRTRSRKLAADIGLLAVAATFAVPLAWVLLSALDPKAD
                     VGMKAPDGITLDNFDAVLTDEITFTPMLNSLLLCGGGTLLTVISAALAAYPLSRYRSRL
                     NRPFMLTILFATSLPITAIMVPVYALFVRVDLIDTMQGTIFFFAASQLPFAIWLMKNFM
                     DGVPKELEEAAWTDGASPFQSLIRIVLPLMGPGVAVVTVFSFVMMWGNFFVPFMLLLSP
                     DQMPAAVSINDFFGSKGAIVYGQLAAFSLIYSTPVILLYVLVARKLGGGFALGGAVKG"
     misc_feature    7746..7762
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     misc_feature    7759..7772
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(7764..7782)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.74"
                     /tool="antismash"
     gene            7885..8514
                     /locus_tag="IE274_RS04565"
                     /old_locus_tag="GCM10010349_09190"
     CDS             7885..8514
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438181.1"
                     /locus_tag="IE274_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09190"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_372446986.1"
                     /transl_table=11
                     /translation="MAPGHVAYGIRASYGLAHVTPDTVMAWERGLAAPNAAELAALAAT
                     LWCSPGELMGAATTLREHRLARGLAPEDVARGAGVEIQAYLRMEETDHWRGTDRQSAAL
                     ARTLRLSLPDFVTVTGRADDLAGLLRSAVTTRWQGYIRPVSKLLAVEKRDVEGPLRKLH
                     DDYQSRMVRTLSWGGGASADASGHAGRDFLDRILDHFWPLVPDLTD"
     misc_feature    8927..8944
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    complement(9208..9222)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.18"
                     /tool="antismash"
     gene            9208..9981
                     /gene="uppS"
                     /locus_tag="IE274_RS04570"
                     /old_locus_tag="GCM10010349_09210"
     CDS             9208..9981
                     /EC_number="2.5.1.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="uppS"
                     /inference="COORDINATES: protein motif:HMM:TIGR00055.1"
                     /locus_tag="IE274_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09210"
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="WP_190114271.1"
                     /transl_table=11
                     /translation="MSPLPRDYPDTTGLPDPSGPTATREGFPQVANNPPRHVAFIVDGN
                     RRWARAHGHPVEQGHQEGADNVCRAVHWCEAVGIETTTWWLLSTDNLNRTTAELHKLLD
                     IISELTRRLAATGHWRMRHLGDPRLLPRSLAAALSEAETTTRHNRGPQINFAVGYSGRE
                     DILAAARLIAHQAVTSAGFSVSERSFAQALSTSGLPDPDLVIRSSGEQRLSGFMLWQAA
                     LAELYFCPVLWPDFTQSDLHRALAFYANRQRRFGK"
     misc_feature    9799..9801
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11095
                     /locus_tag="IE274_RS04575"
                     /old_locus_tag="GCM10010349_09220"
     CDS             10001..11095
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="IE274_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09220"
                     /product="terpene synthase family protein"
                     /protein_id="WP_190114272.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-15, bitscore: 52.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQGPLLFPHPKTTDDIAGSYHSLKPWLLAHLVKGRATYPEHPQT
                     SRLESAVLAWATDLGLSEDHIKITSEATPGHLVGLFAPQAPWDVLLPLAKLQMILFWLN
                     SVDLGSDQPVGQLVEPVRATLEKGRSPSDGPDILRPLASLRDDIVAAGGAGLIPGFTQL
                     LLGFLHEYTARQAWENGAPLPSLDRYLRHRTRTAGIVLGMWVQRLQPGLVGPGEKLPEP
                     LLQLMKQGSLLVGLDNDLHSCHVAAESGEQLSLVGVICQEYGIPLDMAFSCALTLNAAM
                     RYENANTAAAIHADTSLPDTARKHAQAIFHWVDSVYTWSLETPRYGLRSPDAPEVPASS
                     HLNGEASSHLSGEACSHLNGEQQP"
     gene            11092..12459
                     /locus_tag="IE274_RS04580"
                     /old_locus_tag="GCM10010349_09230"
     CDS             11092..12459
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237582.1"
                     /locus_tag="IE274_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09230"
                     /product="cytochrome P450"
                     /protein_id="WP_190114273.1"
                     /sec_met_domain="p450 (E-value: 4.1e-80, bitscore: 265.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNSRPVPLAPKARPLVGHLVPLLRNPLEFLNSLPAHGDLVRIRL
                     GPFTLVAICDPELTRRALVDDRVFDKGGPIFDRVREVVGDDGLASCPYSAHRRLRRLAQ
                     PAFHPARFPDYAKAMSPCIEDVADSWRAGQVLDVPTEMMTITSKVTAATLFSGALPAGE
                     LGPVLKDVKTFFDGFYQRMFMVPPLDRLPTPGNRSHVRACARLRDAFDQIIAQRRAEGV
                     DHDDLLSALIMAHDAEGDGHGMTDAEISDTIVTFFLAGTETTAALLAWALDLLARHPRI
                     ERRLHAEVDTVLNGARATHADLPRLELTHRVITETLRLRPPGWIFTRTVTADTHLGGYR
                     LPAGSSVVYSPYLIHHRPDLYDDPETFDPDRWDPERPQPPRHALLPFAVGARKCIGDTF
                     GMTEAVLALATIAARWRLERLPGQQVRPALGLALRPRRLLMRATPRTDARDFAAAP"
     gene            complement(12456..13481)
                     /locus_tag="IE274_RS04585"
                     /old_locus_tag="GCM10010349_09240"
     CDS             complement(12456..13481)
                     /EC_number="2.7.1.11"
                     /GO_function="GO:0003872 - 6-phosphofructokinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983263.1"
                     /locus_tag="IE274_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09240"
                     /product="ATP-dependent 6-phosphofructokinase"
                     /protein_id="WP_190114274.1"
                     /transl_table=11
                     /translation="MRIGILTAGGDCPGLNAVIRSVVHRAVTNYGDEVIGFEDGYAGLL
                     DGRYRTLDLNAVSGILSRGGTILGSSRLERARFRAACDNAKELIEKSGFDALIPIGGEG
                     TLTAAKMLSDAGVPVVGVPKTIDNDISSTDRTFGFDTAVGVATEAMDRLKTTAESHQRV
                     MVVEVMGRHAGWIALESGMAGGAHGICLPERPFDPADLVKMVEERFARGKKFAVICVAE
                     GAHPADGTMNYGKGAIDQFGHERFQGIGTALAFELESRLGKEAKPVILGHVQRGGTPTA
                     YDRVLATRFGWHAVEAVHRGDFGHMTALRGTDIVMAPLAEAVTELKTVPKDRMDEAESV
                     F"
     gene            13682..15787
                     /gene="pta"
                     /locus_tag="IE274_RS04590"
                     /old_locus_tag="GCM10010349_09250"
     CDS             13682..15787
                     /EC_number="2.3.1.8"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pta"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003993051.1"
                     /locus_tag="IE274_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09250"
                     /product="phosphate acetyltransferase"
                     /protein_id="WP_190114275.1"
                     /transl_table=11
                     /translation="MTRSVYVTGIDRGDGRQVVELGVMELLTRQVDRVGVFRPLVHDGP
                     DRLFELLRARYRLAQDPASVYGMDYHEASALQAEKGTDELVSQLVDRFHAVARAYDVVL
                     VLGTDFAATQLPDELALNARLANEFGASVLPVVGGKDQTAESVRAETRNAYRAYDSLGC
                     DVLAMVTNRVAPADRDGIHERLAARLPVPCYVLPDEPALAAPTVAQITHALGGKVLLGD
                     DSGLARDALDFVFGGAMLPNFLNALTPGCLVVTPGDRADLVVGALAAHSAGTPPIAGVL
                     LTLNEQPGPEILRLADRLAPGTPVVAVEGGSFPTAQELFALEGKLNAATPRKAETALGL
                     FERYTDTTDLLRRLSVFGSDRLTPMMFEHKLLERARADRRRVVLPEGTEERVLRAADVL
                     LRRGVCDLTLLGPVEAIRKKAADLGIDLKDAQLIDPATSDLRQGFAEEYARLRAHKGVT
                     VELAYDVVADVNYFGTLMVQGGLADGMVSGSVHSTAATIRPAFEIIKTKPEASIVSSVF
                     FMCLADKVLVYGDCAVNPDPNAVQLADIAVQSAATADQFGVEPRIAMLSYSTGTSGSGA
                     DVDKVREATELVRDQRPDLKIEGPIQYDAAVEPSVAATKLPGSDVAGQASVLIFPDLNT
                     GNNTYKAVQRSAGAIAVGPVLQGLRKPVNDLSRGALVQDIVNTVAITAIQSQSPASQPP
                     TEKAIPQ"
     gene            15784..17019
                     /locus_tag="IE274_RS04595"
                     /old_locus_tag="GCM10010349_09260"
     CDS             15784..17019
                     /EC_number="2.7.2.1"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008776 - acetate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009305747.1"
                     /locus_tag="IE274_RS04595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09260"
                     /product="acetate kinase"
                     /protein_id="WP_190114276.1"
                     /transl_table=11
                     /translation="MSSTRVLVLNSGSSSLKYQLLDMADSARLAVGLVERIGEETSRLK
                     HTPLTGDGAERERTGPIADHEAALKAVAAELAADGLGLDSPELAAIGHRVVHGGLKFTE
                     PTVIDDAVLAEIERLVPVAPLHNPANITGIRTARALRPDLPQVAVFDTAFHTTMPEAAA
                     RYAIDVATADQHRVRRYGFHGTSHAYVSRTTAELLGKAPEDVNVIVLHLGNGASASAVR
                     GGRCVDTSMGLTPLEGLVMGTRSGDLDPAVIFHLARVGGLSIDEIDTLLNKKSGLIGLC
                     GDNDMREIRRRVDEGDEQARLAFDIYIHRLKKYIGAYYAVLGRVDAIAFTAGVGENAAP
                     VRAAAVAGLEELGLAVDGELNAVRGDEPRLISPGYARVKVAVVPTDEELEIASQTYALV
                     GRHEERLRRMGN"
     gene            17094..18524
                     /gene="pyk"
                     /locus_tag="IE274_RS04600"
                     /old_locus_tag="GCM10010349_09270"
     CDS             17094..18524
                     /EC_number="2.7.1.40"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004743 - pyruvate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030955 - potassium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pyk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060103.1"
                     /locus_tag="IE274_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09270"
                     /product="pyruvate kinase"
                     /protein_id="WP_190114277.1"
                     /transl_table=11
                     /translation="MRRSKIVCTLGPAVDSEDQLVSLIEAGMNVARFNFSHGTHAEHQG
                     RYDRVRAAAERTGRAIGVLADLQGPKIRLETFAEGPVELVRGDEFTITTEDVPGDKSIC
                     GTTYKGLPGDVSKGDQVLINDGNVELRVVEVAGPQVKTIVVEGGVISDHKGINLPGAAV
                     NVPALSEKDIEDLRFALKMGCDMVALSFVRDADDVKDVHKVMDEEGRRVPVIAKVEKPQ
                     AVANMEGVVAAFDAVMVARGDLAVEYPLEKVPMVQKRLVEMCRRNAKPVIVATQMMESM
                     ITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPIETVKTMSKIVTAAEEELLAKG
                     LQPLVPGKKPRTQGGSVARAACEIADFLDGKALVAFTKSGDTARRLSRYRAAQPILAFT
                     TDTSTRNQLALSWGVEAYVVPHVDNTDAMVELVDAEVLKLQRYNDGDTMVITAGSPPGI
                     PGTTNMVRVHHLGGGDRD"
     misc_feature    17104..17118
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     misc_feature    complement(17106..17117)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
     gene            complement(18687..20111)
                     /locus_tag="IE274_RS04605"
                     /old_locus_tag="GCM10010349_09280"
     CDS             complement(18687..20111)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982588.1"
                     /locus_tag="IE274_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09280"
                     /product="hypothetical protein"
                     /protein_id="WP_229909223.1"
                     /transl_table=11
                     /translation="MRTGPRHAAPKKPLLTRLHVPAGKAIALAAMPTAVLMGMGLTPQL
                     AQAKPGVPKNPFRDGPCVTAPDEQSKEAEKDEQDARAKAAKKAEDKAEAARKKADEAED
                     KADGEDGQAGKGADKDGDVSANGSSGSSKPSGGDGDDGKSGSTPSGDADADSGKGSGDG
                     GKDDEDAAAEPDPAEPKNPLDPLGLGDALKDILTPEEKRAEEKKEAERESADEKSSDSS
                     DRDAEGTDGDAKDSDGTDKDTKPVEDTLDKAKDGLKDTAGKAEDRLRDAADKADDLADK
                     AEKAADKAKDKAEGKAEDDDEAKDPMAADEDGKKPFPCVVEKKVDGDDEQSPAPIPNQP
                     WHLEASSLLLKGADYKGVVNLKMPNGQTKQALKYIISGGTDIGDLHQIVESPNGKKYHV
                     QAAKGSTSTIRKGDTTMYTERISGNLFGLIPITFDPEHPPPLNLPLIYFTNVKVQQAGQ
                     FGGELTIPGLHQSITD"
     gene            complement(20149..20727)
                     /locus_tag="IE274_RS04610"
                     /old_locus_tag="GCM10010349_09290"
     CDS             complement(20149..20727)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982589.1"
                     /locus_tag="IE274_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_09290"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_190114279.1"
                     /transl_table=11
                     /translation="MSAEAQVGLGNRLGRMRQSFRGWRGQRPFWGGLLTLLGGIPIMYF
                     PYANLTLGTMTIRMATTAGAGSLIIGVLLVVLGLTMWFQPMSRVFAGVAAILLALVSLV
                     VSNFGGFVMGFLLALIGGALGVSWMPSKPEKRSRRRAQAPDAGGFDDGAPEPAAAGAAR
                     GAVPEAGGATDDFSGTSPDNGTNGRNRAG"
ORIGIN
        1 cccggtcgcc ctcgcggaca cggcgctgcc gccgacgctc gtgtatccgg tccggccgcg
       61 tccggccgac gccgcccggc ccgcgtacga gggtctcgct ccgctgctcg gccacacccg
      121 ggcggccgtg ctccaggcac tcggcggcga tcccaccacc acggaactgg cgcgccgggc
      181 cggggtctcc ctctcctcgg cgagcgaaca cgccgccgtc ctgcgcgagg cgggcctggt
      241 ctccagcgtc cgccagagca acgcggtaca ccacgtgctg acgcccctgg gttcggcgct
      301 gctgaggggg aaccaacagc ccgtcgtggg ggtcccccct gctccatcgg agctcgggag
      361 aacttgagga cggggccgag agccgtttcg gccccggccc cgtccagggg cacgcgaggg
      421 tcagaccttg acggcggccg cctcatccgc ggcggcccgt cccgcgggga cctcgtcctc
      481 ggcctcggac gcgggcttct tctccaggga aggccccacg tccccgtggt cgtcatcgag
      541 aagcgtccgc tcgtcgaacg gaatcctgcc gtcgaggacg gcggccaccc gctcccggtc
      601 gacctccttc gtccacgtac cgatcaacaa cgtggccacc gcgttgccgg cgaagttcgt
      661 cagcgcccga gcctcgctca tgaagcggtc gacaccgatg atcaggccga cgccgtcgac
      721 gagggcgggc ttgtgcgact gcaggccgct ggcgaggaca gcgatgcccg agccggacac
      781 ccccgccgcg cccttggacg cgatcatcat gaacagcagc agcgagatct gctcgccgat
      841 gcccagcggc tggtccatcg cgtcggcgat gaacagcgac gccatcgtca ggtagatcat
      901 cgtgccgtcg aggttgaagg agtagccggt cggcacggtg atgccgacga cgggacggct
      961 gacgcccagg tgctccatct tcgcgatgag ccgcggcagc gccgactccg acgaggacgt
     1021 ggacaggatg agcaggaact cccggcccag gtacttgagc agcttgaaca ggttcacgcc
     1081 ggtggcaagg cgcagcagcg tgccgagcac caccaggacg aacagcgcac aggtgatgta
     1141 gaagccgatc atgatggtgg cgagcgcctt caaggcgtcc gtaccggtct cgccgatcac
     1201 ggcggccatc gcgccgaacg cgccgatggg cgcggcccac atgatcatgc ccaggatgcg
     1261 gaagaccagc ttctggatgt gctgcacccc gcgcagcacc ggctcgcccg tcttgcccat
     1321 ggcctgcagg gcgaagccga cgaggagggc caccaggagg gtctggagga cctcgccctc
     1381 ggtgaaggcg gagaccatcg tcttggggat gatgccgagc gcgaagtcga ccaggccctt
     1441 gtccgcctcg tcggcggcgg tgtggcccgc ctccttgtcc gacgaggtca ggtccatgcc
     1501 gtcgccgggg tgcaggatgt tgccgacgat caggccgatg gcgagggcga ccacggacat
     1561 cgccatgaag taggcgagag cgagcccgcc gaccttgccg accttcgccg cctgccggac
     1621 ggagcccacg ccgagaacga tcgtgcagaa gatgatcggc gagatcatca tcttgatcag
     1681 gttcacgaag ccggtgccga tcggcttgag ctccttggcg aagtccggcg cgatgaagcc
     1741 gacggcgata ccgatcagta cggcgacgat gacggcgatg tacaggtagt gggtccggtc
     1801 ccgtttggcg ggcggtgcgc ccgtaccggc ggtgtcgacc gccgtctgtc cctctgccac
     1861 ggggtgcctc cttgggctac gtacgctgcg tacgactggc gtctggctcc tcgcccgtcg
     1921 tgcggctcac gtcctggcga ttccgggtga ctatctcccg gcctgtgacg gcggtcaccc
     1981 ttacgttcat ttagttcgca catacacgtc acggcagact gggaacatgc cccaggtccc
     2041 ccgaccgccc catccgcccc gccgaccccg cgggccgcgc agcctcgccg gtcagctctt
     2101 cgcgatgcag gtggtcctgg tggcggtcgt ggtcgcgggc tgcgccctgt tcacgtacct
     2161 gagcgaccgg aaccaggccg aggaggccgc gctccgccag gccacggccg ccgcccgcgc
     2221 ggtggccgac tcgccgtcgg tgcgcgaggc gatccgcggc gaggacccgt cccgcaggct
     2281 gcagccgtac gccaccgacg tgcagctgca caccggcgtc gacttcgtga cgatcatgga
     2341 tccgcgcggc atccgctgga cccaccccga ccccgaccgc atcggcgagc gcttcctcgg
     2401 ccacaccgcg gaggccctgc gcggccagac cttcaccgag atctacaccg gcaccctcgg
     2461 cccctccgcg cgcgtggtca cgcccgtctt cgacggcggg gacgaccggc gcggcgagca
     2521 cggccggatc gtcggcctgg tcagcgcggg catcaccatc gacgccatca gcgagaaggc
     2581 ccgcggccag ctcctcgcgc tgctcggcgt cgccgtcgcc gcgctcgccc tcggcgccgt
     2641 cggcacctac gtgatcaacg cccgcctgcg ccgcagcacc cacggcatga acgccggcga
     2701 gctgagccgc atgcacgact accacgaggc cgcgctgcac gccgtccgcg aagggctgct
     2761 catgctcgac gggcggcgcc gcgtcgccct catcaacgac ggcgcccgcg agctgctcgg
     2821 cgcgcccgag ggtgtcgtcg gccggtacgt caccgacctc ggcctgcccg cgccgctcac
     2881 cggcgcgctg ctcgacaccc ggccgcgggt ggacgaggtg catctgacgg ccgaccgggt
     2941 gctcgtcgtg aacacctcgc cggtgtccgg cggcgaccgc aagggcaccg tcgtgaccct
     3001 gcgcgaccac accgaactcc aggccctcgc gggcgagctg agctccgaac gcggcttcac
     3061 ccgggcgctg cgctcgcagg cccacgaggc cgcgaaccgg ctgcacaccg tggtctccct
     3121 catcgagctg ggccgcgccg acgaggccgt ggagttcgcc accgccgagc tggagctggc
     3181 ccaggccctc accgaccagg tcgtcgccgc cgtcaacgaa cccgtcctcg ccgccctgct
     3241 cctcggcaag gccgcccagg ccaacgagca cggcgtcgag ctcgtcgtct ccgccgacac
     3301 cagcgtcgac gacggcatgc tccccaccgg cctgccgccc cgcgacctgg tcaccatcct
     3361 cggcaacctc atcgacaacg ccgtcgacgc ggcccagggc tcccccgcgg cccgcgtcac
     3421 ggtcacggtc cgcgcggagt ccggcggcct cctcctccgc gtcacggaca ccggccccgg
     3481 cgtcgacccc tcccaacgcg aatcggtctt ccaacacggc tggagcacca aggccccctc
     3541 cggccgcggc ctcggcctct ccctggtcca ccagacggtg acccgccacg ccggcacctt
     3601 gaccttgacg gaaccggagg agggcggggc agagttcacg gcgagcctgc ccttggaacc
     3661 cgcacgggtc ggcgtacgta ccgacggaaa ggccgccaga tgaccgaccc tcagcccatc
     3721 cgggtcctgg tcgtcgagga cgaccccgtc gcggccgacg cccacgtcct ctacgtgaac
     3781 cgggtccccg gcttcgaggc caccgcgacg gcccacacgg ccgccgaagc ccgcagagcc
     3841 ctggaccggg ccccggtcga cctgatcctc ctcgacctga acctccccga cggccacggc
     3901 ctggccctgg cccgcaccct ccgcgcggcg ggccaccgcg cggacgtcat cgcggtgacc
     3961 tcggcccgcg acctggcggt ggtccgcgag ggcgtctccc tgggcgtcgt ccagtacgta
     4021 ctgaaaccct tcaccttcgc aacgctccgc gaccgcctca cccgctacgc ggaattccgc
     4081 aacgccgcag gcgaggcgac gggccaggac gaggtggacc gcgccctcgc ggccctgcgg
     4141 gccccggccc ccgccgccct gccgaagggc ctcagcggcc ccaccctgga gaaagtgacc
     4201 cgcacgctcc aggacgcggc cccggacggc ctcaccgccg cggcgaccgc ggacaccacc
     4261 ggcctctccc gcatcacggc ccgccgctac ctggagcacc tggtgaccac cggccgcgcc
     4321 gcccgcagcc cccagtacgg ccacgtgggc cgcccggaac tgatctaccg ctggctgccc
     4381 ccggcctgac cgcccccggg gcccgaggcc tgatccacaa cccccaaacc cccaccccat
     4441 aacaacgttg tcacgttact gacaagcgtc aacgcactgc tgcagcaacc ccgttgcaag
     4501 ggcattgacc ttgctccgag cccgcgctta cgttcaccgg cagcagcccc gcgcggcagc
     4561 acccccgcgc cgcggcgcgg ccgcgtcgga ccgtaggagg tcgtgcccgt gcgccccacc
     4621 gcccccgccc ctctgctcct ggcagccgtg ctcgccgcct ccaccctgac cgcctgcggc
     4681 ggcggctccg gcgacgaccc ggacaccgtg aaggtctcgt acaaacagtc gatggacaac
     4741 aagatccggg tgatggacga ctacctggag tcgatgaaga agcagttcga gaaggccaac
     4801 ccgggcaaga aggtgaaact ggtgccgatc aaggcgccgg acgccgagta ctacacgaag
     4861 gtgcagcaga tgctgcgctc gccgaagacc gccccggacc tggtctacga ggacaccttc
     4921 ctcatcaact ccgacatcac cagcgggtac ttgaagccgc tcgacccgta tctggacaag
     4981 tggaaggagt ggccgaagtt catcgacacg gccaaggcgg cggcgaaggc cgaggacggc
     5041 aagacgtacg gcgtgccgga cggcacggac acgcgcgggc tctggttcga caaggacatc
     5101 ttcaagaagg cgggcctgcc cgcgaactgg cagccgaaga actgggacga gatcctggac
     5161 gcggcccgca ccatcaagga gaaggtcccc gacgtcgtcc cgctgaacgt ctacaccggc
     5221 aaacccggcg gtgagacctc gtccatgcag ggcatggaaa tgctgctcta cggcacgggc
     5281 gagaacccgc tgtacgaccc gaaggcgaag aagtgggtgg tgggcggcca gggcttcaag
     5341 gactccctga agttcgtgga gacggtctac aaggagaagc tcggccccga cgtcgaggac
     5401 gccctcgacc cgaacatggc cacgcgggtg cgcggcgagt tcctgcccga gggcaagctc
     5461 ggcatcaacc tcgacggctc ctggctgcca caggactggc tgccgggctc cgggcacgaa
     5521 tggcctcagt ggtccaagga gctggggctc gcggcgatgc ccacgcagca cggccaggcg
     5581 cccggcaagg tgagcatgtc cggcggctgg acctgggcga tcccgtccaa ggcggacaac
     5641 gccgacctgg cgttcaagtt catcgagacc atgcagacca aggagaacgc gaagaagtgg
     5701 tacatcgcca actccggcat ctcggtccgc gaggacgtcg ccaaggaccc ggcgtacgtg
     5761 caggcgcagc ccggcatcaa gttcttcacc gacctggtcg cgtccacgca ctaccgcccg
     5821 gcgttccccg cgtatccgaa ggtctccacg gcgatgcagg aggccatgga gcaggtcacg
     5881 acgggcgacg gctcggtgga caaggcggcg agcggctatg acgacgaggt cgggtcggcc
     5941 accgacggca aggtgatcga gaagtgacgg ctcccccggg ccaccggcgg ctcgcccgct
     6001 ccctggcccg ggccctgccg gtgtcgcccg cggtcgtcct gatggccctg ttcctcgcgg
     6061 gcccgatcgg ctactgcgcg tacatcgcct tcacggacct ccagctcacg ggccaggccc
     6121 acgagtcgtt cgtcggcctc gagaacttcc ggacggcgtt cgacgacgag gacttcatca
     6181 acgcggtctg gctgacgctg gtcttcacgt tcctgtcgtc gatcgtcggc cagaacaccc
     6241 tgggcctggc cctcgcggcg ctgatgcagc gggcgtccaa gacggtccgc acgatcaccg
     6301 gggcggtcgt cgtcacggcg tgggtgctgc cggaggtggt cgcgggcttc ctcctctacg
     6361 ccttcttccg ccgcgacggc accctcaacg cggtcctgga cttcctccac ctgccgtccc
     6421 agaactggct ctacaccctg ccgatcctgg cggtgtcgtt cgccaacgtc tggcgcggca
     6481 cggccttctc gatgctcgtg tactccgccg ccctgaacga gatccccaag gagatcaccg
     6541 aggccgcgga ggtggacggc gcgagcggct ggcgccgcat gtggcacatc accctgccga
     6601 tgatccgccg ctccatcggc accaacctga tgctcaacac cctgcagacc ctgtcggtct
     6661 tcggcctgat ctgggtgatg acgcgcggcg gccccggaaa ccgcagccag accctcccgc
     6721 tgttcatgta cgaacaggcc ttccagaaga gcatgatcgg ctacggcacg gccgtggcgc
     6781 tgctcctcct cctggtcgga tccctgttct cactcatcta catgcgcctg ctgcgcacgg
     6841 aggtctgagt gtcgtccaca ccgtccgcac gccgtacgag aagccgcaaa ctggccgcgg
     6901 acatcggcct gttggccgtc gccgcgacct tcgcggtacc gctcgcctgg gtgctcctgt
     6961 ccgcgctcga ccccaaggcc gacgtgggca tgaaggcccc cgacggcatc acgctcgaca
     7021 acttcgacgc ggtcctcacc gacgagatca cgttcacgcc gatgctgaac agcctcctgc
     7081 tgtgcggcgg gggcactctc ctgaccgtga tcagcgcggc cctcgccgcg tacccgctgt
     7141 cccgctacag gtcccgcctg aaccgcccct tcatgctcac gatcctcttc gccaccagcc
     7201 tgcccatcac cgcgatcatg gttccggtgt acgcgctgtt cgtccgcgtc gacctcatcg
     7261 acaccatgca gggcacgatc ttcttcttcg ccgcgtccca gctcccgttc gcgatctggc
     7321 tgatgaagaa cttcatggac ggcgtcccca aggaactgga ggaggccgcc tggacggacg
     7381 gcgcatcgcc cttccagtcc ctgatccgga tcgtcctgcc cctgatgggc cccggtgtgg
     7441 ccgtcgtgac ggtcttctcg ttcgtcatga tgtggggcaa cttcttcgtc cccttcatgc
     7501 tgctcctgtc ccccgaccag atgccggcgg cggtcagcat caacgacttc ttcggctcca
     7561 agggcgccat cgtctacggc cagctcgcgg cgttctccct catctactcc acgccggtga
     7621 tcctgctgta cgtcctggtg gcgcggaagc tgggcggggg gttcgccctg gggggtgcgg
     7681 tcaagggctg attcccgcac aaaggggggc gcgtggagca catggagggc gcccgccagc
     7741 cgtactttca tatgagccgc aaccctgtgt gaacagaccg tagtcgccac ccccatacgg
     7801 ccataccgtg tgcccgtgca accgagccag cccacgccgc ccttcaactt ccccgccgcg
     7861 cgccgcctcc gggaggcgct gggcatggct ccgggccacg tcgcgtacgg catacgggcc
     7921 agctacggcc tcgcccatgt cacgccggac accgtcatgg cgtgggagcg cgggctcgcc
     7981 gcgccgaacg ccgccgagct ggccgcgctc gcggcgacgc tgtggtgttc gccgggcgag
     8041 ctgatgggcg cggccacgac gctgcgggag caccgcctcg cccgcggcct cgccccggag
     8101 gacgtggcgc gcggggcggg cgtggagatc caggcgtatc tgcgcatgga ggagaccgac
     8161 cactggcgcg gcacggaccg ccagtccgcg gccctcgcgc gcacgctgcg gctctccctg
     8221 cccgacttcg tcacggtgac gggccgcgcc gacgacctcg ccgggctgct gcgcagcgcg
     8281 gtgacgaccc gctggcaggg ctacatacgc ccggtcagca agctgctcgc cgtggagaaa
     8341 cgggacgtcg agggcccgct gcgcaagctg cacgacgatt accagtcccg gatggtgcgc
     8401 acgctcagct ggggcggcgg cgcgagcgcg gacgcgtcgg ggcacgcggg ccgcgacttc
     8461 ctggaccgca tcctcgacca cttctggccg ctggtgcccg acctcacgga ctgaggcctg
     8521 ggggcgcggg cccgcccgcc cggcaccggc gccccggacg gcaccccggg catctccgag
     8581 cgcacgcgcc cctcctcctg gagagggcgc gtgccctcgc cccggggacc tggcccgcgt
     8641 cgcgccgtac gtgaccgggc tcatccgccg cttcagcgag tgctcgaccc atgaacccgg
     8701 tcctgcgcct gcgcccggac cggatgaccc gcacccggcg tcggcccggc ccactccgct
     8761 cccacgcgcc ccgcagtcgg agcgcgtgcg accggcggcc cggcgcgcgg gccgtgcggt
     8821 gcggacgcag cgctgcgagg ggcgtctcga acgccctccc caggagccgt ggagggcctt
     8881 ccattggtgg gtgcgcacgt caggcgctgc tggacgcgcc tttccaaacc cggtagagcg
     8941 gagaaggatt cccggggagg acaccgccgg ggaaaccgcc gccggcactg cgaccactgt
     9001 ggaggcgctc tccgcgggca ttccgtttca ccaccggaat cctgcgtgat catcggtaac
     9061 ttccgcaccg gcggggtggc ttcgaccccc gcccaggcat ttcccccgcg gcccatccac
     9121 cgccctttcc ccttgccttg ctcatagcgc ccgctgcatt cgtattggct gtgcatgccc
     9181 tggtcccagg cgataaggaa gtgcccgatg agtccgctcc cacgcgacta ccccgacacc
     9241 acaggtctac cggatccatc cggccccacc gcgacgcggg aaggattccc ccaggtcgcg
     9301 aacaaccccc cacgtcacgt cgccttcatt gtggacggaa accgccgttg ggcacgcgcc
     9361 catggccatc ccgtcgagca gggccaccag gagggcgcgg acaacgtctg ccgggccgtt
     9421 cactggtgtg aggccgtggg catagagacc accacctggt ggctgctctc gacggacaac
     9481 ctcaaccgca cgacggccga gctccacaaa ctcctggaca tcatctccga actgacccgc
     9541 cggctggcgg caaccgggca ctggcgcatg cgtcacctcg gggatccccg gctgctcccc
     9601 cgttccctgg cggccgcgct gagcgaggcg gagaccacca cccgccacaa ccgtggccca
     9661 cagatcaact tcgcggtcgg ctacagcggc cgggaggaca tcctcgccgc ggcgcgcctc
     9721 atcgcccacc aggcggtcac gtccgccggc ttctccgtgt ccgagaggtc gttcgcgcag
     9781 gccctgtcca ccagcgggtt acccgatccg gacctggtga tccgcagctc cggcgaacaa
     9841 cggctgtccg ggttcatgct ctggcaggcg gctctcgccg aactctattt ctgccccgtc
     9901 ctgtggcccg acttcaccca gtcggatctc caccgcgccc tggccttcta cgccaaccgt
     9961 cagcgccgtt tcggaaagta gcgccggaag gaagtacgcc atgtcccaag ggcctctcct
    10021 gttcccccac cccaagacga cggacgacat cgccggctcc taccactccc tcaaaccctg
    10081 gctgctcgcc catctggtca agggacgtgc aacgtacccc gagcatccgc agaccagccg
    10141 tcttgagtcc gccgttctcg cctgggcgac cgacctcgga ctgagcgaag accacatcaa
    10201 gataacgagc gaagccaccc ccgggcacct ggtggggctt ttcgccccgc aggccccctg
    10261 ggatgtgctg ctcccgctgg ccaagctgca aatgatcctg ttctggctga actccgtgga
    10321 cctcggcagc gatcagccgg tcggtcagct ggtggaaccc gtccgagcga ccctggagaa
    10381 gggacgttcc ccgtccgacg gaccagacat cctcaggccg ttggccagcc tccgcgacga
    10441 catcgtcgcg gcgggagggg ccgggctgat acccggcttc acgcaactcc tgctgggatt
    10501 cctgcacgag tacacggctc ggcaagcatg ggagaacggg gcacctctcc cgagcctgga
    10561 ccggtacttg aggcatcgga cgcgcacggc ggggatcgtt ctcggcatgt gggtccaacg
    10621 acttcagccg ggcctcgtcg ggccgggtga gaagcttcct gaaccactgc tgcagctcat
    10681 gaaacagggc agcctcctcg tcggtctgga caacgacctg cacagttgcc acgtggccgc
    10741 cgagtcgggg gaacagctca gcctcgtcgg cgtcatctgc caggagtacg ggattcccct
    10801 ggacatggcc ttctcctgcg cgctcactct caacgccgcc atgcgctacg agaacgcgaa
    10861 caccgctgcc gcgatccacg cggacacctc cctgcccgac acggccagga agcacgccca
    10921 ggccatcttc cactgggtcg actccgtcta cacctggtcg ctggagacgc cccgctacgg
    10981 gttgcgcagc cccgatgccc cagaggtccc ggcgtcctcc cacctgaacg gagaagcgtc
    11041 ctcccacctg agcggagaag cgtgttccca cctcaacgga gagcagcagc catgacgaac
    11101 tcgcgcccgg tcccccttgc ccccaaggca cggcccctcg tcggtcatct ggttccgctg
    11161 ctccgcaacc cgctggagtt cctcaactcg ctgcctgccc acggtgacct cgtccgcatc
    11221 cggctgggcc ccttcacgct ggtggcgatc tgtgatccgg aactgacccg acgtgccctg
    11281 gtcgacgacc gcgtcttcga caagggcggc ccgatcttcg accgggtgcg ggaagtcgtg
    11341 ggcgacgacg ggctcgccag ctgtccgtac agcgcgcacc ggcggctgcg ccggctggcc
    11401 cagcccgcct tccacccggc gcggttcccc gactacgcga aggccatgag cccctgcatc
    11461 gaggacgtgg ccgattcgtg gcgtgccggg caggtcctgg acgtgcccac cgagatgatg
    11521 accatcacgt ccaaggtcac ggccgccacc ctgttctccg gtgcgctgcc cgcaggcgaa
    11581 ctcggcccgg tcctcaagga cgtgaagacc ttcttcgacg gcttctacca gcgcatgttc
    11641 atggtccccc cgctggaccg gctccccacc ccgggcaacc gctcccacgt gcgcgcgtgc
    11701 gcccggctac gcgacgcctt cgaccagatc atcgcccagc gccgcgccga gggcgtcgac
    11761 cacgacgacc tgctctcggc tctgatcatg gcccacgacg ccgaaggcga cgggcacggc
    11821 atgaccgacg cggagatcag cgacacgatc gtcaccttct tcctcgccgg tacggagacc
    11881 actgccgccc tcctggcctg ggccctcgac ctgctggccc ggcacccccg gatcgagcgg
    11941 cggctgcacg ccgaggtcga caccgtcctg aacggagcca gggcgaccca cgccgacctg
    12001 ccccgcctgg aactgacgca ccgcgtcatc accgagaccc tccggctgcg cccgccgggc
    12061 tggatcttca cgcgcaccgt caccgccgac acccacctgg gcgggtaccg gctgcccgcc
    12121 gggagcagcg tcgtctacag cccgtacctc atccaccacc ggccggacct ctacgacgac
    12181 cccgaaacct tcgaccccga ccgctgggat cccgagcgcc cccagccgcc ccggcacgct
    12241 ctcctcccct tcgccgtcgg cgcccgcaaa tgcatcggcg acaccttcgg catgacggag
    12301 gccgtcctcg ccctcgcgac catcgccgcc cgctggcgcc tggaacgcct gcccggccag
    12361 caggtccgcc ccgcgctggg gctggcgttg cggccccgca ggctcctcat gcgggcaacg
    12421 ccccgcaccg acgcacgcga cttcgcggca gctccttaga agaccgactc cgcctcgtcc
    12481 atccggtcct tcggcaccgt cttcagctcg gtgaccgcct cggcgagcgg cgccatcacg
    12541 atgtccgtgc cccgcagcgc cgtcatgtgg ccgaagtcgc cgcggtgcac ggcctcgacg
    12601 gcatgccagc cgaagcgggt ggcgaggacg cggtcgtacg cggtgggggt gccgccgcgc
    12661 tggacgtggc cgaggatgac cggcttggcc tccttgccga ggcggctctc cagctcgaag
    12721 gcgagggccg tgccgatgcc ctggaagcgc tcgtggccga actggtcgat ggcgcccttg
    12781 ccgtagttca tggtgccgtc ggcggggtgc gcgccctcgg cgacgcagat cacggcgaac
    12841 ttcttgccgc gcgcgaaccg ctcctcgacc atcttgacca ggtcggccgg gtcgaagggc
    12901 cgctccggca gacagatgcc gtgggcgccg ccggccatgc cggactccag ggcgatccag
    12961 ccggcgtggc ggcccatgac ctcgacgacc atgacgcgct ggtgggactc ggcggtggtc
    13021 ttcaggcggt ccatggcctc ggtggcgacg ccgacggcgg tgtcgaagcc gaaggtgcgg
    13081 tccgtggagg agatgtcgtt gtcgatggtc ttggggacgc cgaccaccgg cactccggcg
    13141 tcggacagca tcttcgcggc cgtcagggtg ccctcgccgc cgatcgggat gagcgcgtcg
    13201 aagccgctct tctcgatgag ttccttggcg ttgtcgcagg cggcgcggaa gcgggcgcgc
    13261 tccaggcggg aggagccgag gatggtgccg ccgcgggaga ggatgccgct gaccgcgttc
    13321 aggtcgaggg tgcggtagcg gccgtccagc aggcccgcgt atccgtcctc gaagccgatg
    13381 acctcgtcgc cgtagttggt gacggcgcgg tgcacgaccg accggatcac tgcgttgagg
    13441 cccgggcagt cgccgcccgc ggtgagaatt ccgatacgca tcgcgctgtg tctcctgctc
    13501 gctgctgata cttgtgagcc gatccgattg ttccacggcc ccggcggggc cgccgcccgc
    13561 cgtccggcct gcggcctagc cagccgcaga ggtattgtca agagggcacg gccaacaata
    13621 tcgggtgtat ttccggcgct gccgggctgc tcaccagcga agacagagaa ggagagcacg
    13681 cgtgacgcgc agcgtgtacg tgaccgggat cgaccggggc gacggccgcc aggtcgtcga
    13741 gctgggagtg atggaactcc tgacccgtca ggtcgaccgc gtgggcgtct tccgcccgct
    13801 cgtccacgac ggacccgacc gcctcttcga actgctccgc gcccgctacc ggctcgcgca
    13861 ggaccccgcg tccgtgtacg gcatggacta ccacgaggcg tccgcgctgc aggccgagaa
    13921 gggcaccgac gagctggtct cccagctcgt cgaccgtttt cacgccgtcg cccgcgccta
    13981 cgacgtggtc ctggtcctcg gcaccgactt cgccgccacc cagctccccg acgagctggc
    14041 cctgaacgcg cggctcgcga acgagttcgg cgcctcggta ctgcccgtgg tcggcggcaa
    14101 ggaccagacc gccgagtcgg tccgcgccga gacccgcaac gcctaccgcg cctacgacag
    14161 cctcggctgc gacgtcctcg cgatggtcac caaccgggtc gccccggccg accgcgacgg
    14221 catccacgag cgcctggccg cccgcctccc ggtgccctgc tacgtcctgc cggacgagcc
    14281 cgccctggcc gcgccgaccg tcgcgcagat cacccacgcc ctcggcggca aggtgctcct
    14341 cggcgacgac tcgggcctgg cccgcgacgc cctcgacttc gtcttcggcg gcgccatgct
    14401 gccgaacttc ctgaacgccc tgaccccggg ctgcctggtc gtgacccccg gcgaccgcgc
    14461 cgacctggtc gtcggcgcgc tggccgcgca cagcgcgggg acgccgccga tagcgggcgt
    14521 cctgctgacc ctgaacgagc agccgggccc ggagatcctg cgcctggccg accggctcgc
    14581 gccgggcacg cccgtggtcg ccgtcgaggg cggctccttc ccgacggcac aggagctgtt
    14641 cgccctggag ggcaagctga acgcggcgac gccccgcaag gcggagaccg cgctcggcct
    14701 cttcgagcgg tacaccgaca ccaccgacct gctgcggcgc ctgtccgtgt tcggcagcga
    14761 ccgcctcacg ccgatgatgt tcgagcacaa gctcctggag cgggcccgcg ccgaccgccg
    14821 ccgcgtcgtg ctgcccgagg gcaccgagga gcgcgtgctg cgcgccgccg acgtgctgct
    14881 gcgccggggc gtctgcgacc tgaccctgct cggcccggtg gaggccatcc gcaagaaggc
    14941 cgccgacctg ggcatcgacc tcaaggacgc gcagctcatc gacccggcca cgtcggacct
    15001 gcggcagggc ttcgccgagg agtacgcgcg gctgcgcgcc cacaagggcg tgacggtgga
    15061 gctggcgtac gacgtcgtgg cggacgtgaa ctacttcggc acgctgatgg tccagggcgg
    15121 cctggccgac ggaatggtgt ccggctccgt gcactcgacg gcggcgacga tccgcccggc
    15181 cttcgagatc atcaagacga agccggaagc ctcgatcgtg tcgtccgtct tcttcatgtg
    15241 cctggccgac aaggtcctcg tgtacggcga ctgcgcggtc aacccggacc cgaacgccgt
    15301 ccagctcgcc gacatcgccg tgcagtcggc cgccaccgcc gaccagttcg gcgtcgagcc
    15361 gcgcatcgcg atgctgtcgt actccaccgg cacctccggc tcgggcgccg acgtcgacaa
    15421 ggtccgcgag gccaccgagc tggtgcgcga ccagcgcccg gacctgaaga tcgagggccc
    15481 gatccagtac gacgcggccg tcgagccgtc ggtcgcggcc accaagctgc cgggctccga
    15541 cgtcgcgggc caggccagcg tgctgatctt cccggacctg aacaccggca acaacaccta
    15601 caaggccgtg cagcgctcgg ccggcgcgat cgccgtcggc ccggtcctgc agggcctgcg
    15661 caagcccgtg aacgacctgt cccgcggcgc gctcgtccag gacatcgtca acaccgtcgc
    15721 catcacggcg atccagtccc agtcccccgc gtcccagccc cccaccgaga aggcaatccc
    15781 ccagtgagct cgacccgcgt cctcgtcctc aactccggct cgtcgtcgct gaagtaccag
    15841 ttgctcgaca tggccgacag cgcccgcctg gccgtgggcc tcgtcgagcg catcggcgag
    15901 gagacctccc ggctcaagca caccccgctg acgggcgacg gcgccgagcg cgagcgcacc
    15961 ggcccgatcg ccgaccacga ggccgccctg aaggccgtcg cggcggagct ggccgccgac
    16021 gggctcggcc tggactcgcc tgagctggcc gcgatcggcc accgggtggt gcacggcggc
    16081 ctgaagttca ccgagcccac ggtcatcgac gacgcggtgc tcgccgagat cgagcgcctg
    16141 gtgccggtgg ccccgctgca caaccccgcc aacatcaccg gcatccgcac ggcccgggcg
    16201 ctgcgccccg acctgcccca ggtcgccgtc ttcgacaccg ccttccacac gacgatgccg
    16261 gaggccgcgg cccgctacgc catcgacgtg gcgaccgccg accagcaccg cgtgcggcgc
    16321 tacggcttcc acggcacctc gcacgcgtac gtctcgcgga cgaccgcgga gctgctcggc
    16381 aaggcccccg aggacgtgaa cgtcatcgtc ctgcacctcg gcaacggcgc gtccgcgtcc
    16441 gccgtgcgcg gcggccggtg cgtggacacc tcgatgggcc tgacgccgct cgaagggctc
    16501 gtgatgggca cgcgctcggg agatctggac ccggccgtca tcttccattt ggcgcgcgtc
    16561 ggcggactgt ccatcgacga gatcgacact cttctcaaca agaagagcgg ccttatcggt
    16621 ctgtgcggcg acaacgacat gcgcgagatc cgccgccgcg tcgacgaggg cgacgaacag
    16681 gcccggctcg ccttcgacat ctacattcac cgactgaaga agtacatcgg cgcctattac
    16741 gcggttctcg gccgggtgga cgcgatcgcg ttcacggcgg gcgtcgggga gaacgcggcg
    16801 ccggtgcgcg cggccgccgt cgcgggcctg gaggagctgg gtctcgcggt ggacggcgag
    16861 ctgaacgccg tacgcggtga cgagccgcgg ctgatctcgc ccgggtacgc ccgggtgaag
    16921 gtcgcggtcg taccgaccga cgaggaactg gaaatcgcct cgcagactta tgcactcgtc
    16981 gggcggcatg aagagcggct ccgccgcatg ggcaactgag cgccgacccg cccatttgta
    17041 tcttccgcca gatggaatat tccgaagcga aacaaaccga taggatcgcc cccatgcgcc
    17101 gttccaaaat cgtttgcacg ctgggccccg ccgtcgactc cgaagatcag ctcgtttcgc
    17161 tgatcgaagc cggaatgaac gtggcccgct tcaacttcag ccacggcacg cacgccgagc
    17221 accagggccg gtacgaccgc gtccgggccg cggcggagcg gacgggccgc gcgatcggcg
    17281 tcctcgccga cctgcagggc ccgaagatcc gtctggagac cttcgccgag ggccccgtcg
    17341 agctggtgcg cggtgacgag ttcaccatca ccaccgagga cgtgcccggc gacaagtcga
    17401 tctgcggcac gacctacaag ggtctgcccg gcgacgtctc caagggcgac caggtcctca
    17461 tcaacgacgg caacgtcgag ctgcgcgtcg tcgaggtcgc cgggccgcag gtgaagacga
    17521 tcgtggtcga gggcggcgtc atctccgacc acaagggcat caacctgccc ggcgcggccg
    17581 tgaacgtccc cgccctgtcc gagaaggaca tcgaggacct gcggttcgcg ctgaagatgg
    17641 gctgcgacat ggtcgcgctg tccttcgtgc gcgacgcgga cgacgtcaag gacgtccaca
    17701 aggtgatgga cgaggagggc cgccgggtcc ccgtcatcgc caaggtggag aagccgcagg
    17761 cggtggcgaa catggagggc gtcgtcgcgg ccttcgacgc cgtcatggtg gcgcgcggcg
    17821 acctggccgt ggagtacccg ctggagaagg tcccgatggt gcagaagcgc ctcgtggaga
    17881 tgtgccgccg caacgccaag ccggtgatcg tcgcgaccca gatgatggag tcgatgatca
    17941 ccaactcccg ccccacgcgc gccgaggcgt ccgacgtcgc caacgcgatc ctggacggcg
    18001 cggacgcggt gatgctgtcg gccgagtcca gcgtgggcgc gtacccgatc gagaccgtca
    18061 agacgatgtc gaagatcgtc acggcggccg aggaggagct gctcgccaag ggcctgcagc
    18121 cgctcgtccc gggcaagaag ccgcgtacgc agggcggttc ggtggcccgt gccgcctgcg
    18181 agatcgccga cttcctcgac ggcaaggccc tggtcgcctt caccaagtcc ggtgacacgg
    18241 cacgccgcct gtcccgctac cgcgcggccc agccgatcct ggccttcacc acggacacca
    18301 gcacccgcaa ccagctcgcg ctgagctggg gcgtcgaggc gtacgtcgtg ccgcacgtgg
    18361 acaacacgga cgccatggtc gagctggtcg acgccgaggt cctgaagctg cagcgctaca
    18421 acgacggcga caccatggtc atcacggccg gttcgccccc cggcatcccc ggcaccacca
    18481 acatggtccg cgtccaccac ctgggtggcg gcgaccgcga ctgagccacg ggtctccggt
    18541 ccggatcccc gaccagaacc ggaccgggac ccgttgtctc ccgggagtgc cccggcactc
    18601 ccgtgagtac gtgaaaggca tcgagggcgc cccctgcgca agggggcgcc ctcgatgtgt
    18661 cgcggctccc ggaccgggac cgggcctcag tcggtgatcg actggtgcag gccggggatg
    18721 gtgagttcgc caccgaactg gcccgcctgc tgcaccttca cgttggtgaa gtagatcagc
    18781 ggcaggttga gcggcggcgg gtgctccggg tcgaacgtga tcgggatcag accgaagagg
    18841 ttgccggaga tccgctcggt gtacatcgtc gtgtcgccct tgcggatcgt ggacgtggac
    18901 cccttggcgg cctggacgtg gtacttcttg ccgttcgggc tctcgacgat ctggtgcagg
    18961 tcgccgatgt ccgtgccgcc gctgatgatg tacttcagcg cctgcttggt ctgcccgttg
    19021 ggcatcttca ggttcacgac gcccttgtag tccgcgccct tcaggagcag cgaactggcc
    19081 tccaggtgcc acggctggtt cgggatcggc gcgggcgact gctcgtcgtc accgtcgacc
    19141 ttcttctcca ccacgcacgg gaacggcttc ttgccgtcct cgtccgccgc catcgggtcc
    19201 ttggcctcgt cgtcgtcctc ggccttcccc tcggccttgt ccttcgcctt gtccgcggcc
    19261 ttctcggcct tgtcggcgag gtcgtcggcc ttgtcggcgg cgtcccgcag ccggtcctcg
    19321 gccttgcccg cggtgtcctt caggccgtcc ttcgccttgt cgagggtgtc ctcgacgggc
    19381 ttggtgtcct tgtcggtacc gtcggagtcc ttggcgtcgc cgtccgtacc ctcggcgtcc
    19441 cggtccgagg agtccgagga cttctcgtcg gccgactccc gctccgcctc cttcttctcc
    19501 tcggcccgct tctcctcggg cgtgaggatg tccttgaggg cgtcgccgag gcccagcggg
    19561 tccagcgggt tcttgggctc ggcggggtcg ggctcggcgg ccgcgtcctc gtcgtccttg
    19621 ccgccgtccc cggaaccctt gccggagtcg gcgtcggcgt caccggacgg cgtggacccg
    19681 gacttgccgt cgtccccgtc gccgcccgag ggcttcgacg aaccggacga cccgttcgcg
    19741 gacacgtccc cgtccttgtc ggcgcccttc ccggcctgcc cgtcctcgcc gtcggccttg
    19801 tcctcggcct cgtccgcctt cttgcgcgcg gcctcggcct tgtcctcggc cttcttggcg
    19861 gccttggccc tggcgtcctg ctcgtccttc tcggcttcct tggactgctc gtccggcgcc
    19921 gtgacacagg ggccgtcgcg gaaggggttc ttgggcacgc ccggcttcgc ctgcgcgagc
    19981 tggggcgtca ggcccatgcc catcagcacg gcggtgggca tggcggcgag ggctatcgcc
    20041 ttcccggcgg gcacgtgcag ccgggtcagc agcggcttct tcggggccgc gtgccgcggc
    20101 cccgttctca cacgggacgt gtccgcatca gtcccgcggc gcgcctcgtc agccggcacg
    20161 gttcctcccg ttcgtcccgt tgtccgggct cgttcctgag aagtcatcgg tcgcaccgcc
    20221 cgcctccggc acggctccgc gcgcggcccc cgcggccgcg ggctccggag ccccgtcgtc
    20281 gaatcccccg gcgtcgggcg cctgggcgcg ccgcctggag cgcttctcgg gcttggacgg
    20341 catccaggag acgccgagcg cgccgccgat gagggcgagc aggaagccca tgacgaagcc
    20401 cccgaagttg gacaccacca gggagaccag ggcgagcaga atcgccgcga cgcccgcgaa
    20461 cacgcgggac atcggctgga accacatggt caggccgagc acgaccaaca gcacaccgat
    20521 gatcagcgat ccggcaccgg cggtggtcgc catccggatg gtcatcgtgc ccagggtgag
    20581 gttcgcatag gggaagtaca tgatcgggat gccgccgagc agtgtcagca gtccacccca
    20641 gaacgggcgc tgaccgcgcc accctcggaa cgattggcgc attcggccaa gcctgttgcc
    20701 aaggcccact tgcgcttcgg cgctcatgtc gtacagctcc tcgggtatgg cgtgtggttc
    20761 tgtgtgtgcg gattcgggca cggggacggc tcgttggaga gcatgacggc gcccccgcgc
    20821 ccggccgttt cagcgcaaca agtgcggctc agggcagcaa tggcctcaac gacggcctca
    20881 acgacggcct cggtcaagac gaagcggatg agacagcggt gaccgaggcc gttaccgcct
    20941 cagtagcact cgtgcttgcc cttcttgacc gacatgccga ggccagagag cttgaaggtg
    21001 ccggcggtgg tcgcccacgc gcgctgcttc acgtcggtga agcggacctt gtcggcctgc
    21061 tgcgcgaacg agtccgggac gtacttgtcg ccctt
//
