LOCUS       NZ_BMVR01000001        29830 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces flavofungini strain JCM 4753 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVR01000001
VERSION     NZ_BMVR01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces flavofungini
  ORGANISM  Streptomyces flavofungini
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 923124)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650815.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,873
            CDSs (total)                      :: 7,799
            Genes (coding)                    :: 7,638
            CDSs (with protein)               :: 7,638
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 43 of 161
            Pseudo Genes (incomplete)         :: 137 of 161
            Pseudo Genes (internal stop)      :: 10 of 161
            Pseudo Genes (multiple problems)  :: 26 of 161
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 606871
            Orig. end                         :: 636701
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVR01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..29830
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="4"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..29830
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29830
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15830](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..15830
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    83..97
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            complement(279..1160)
                     /locus_tag="IE274_RS02500"
                     /old_locus_tag="GCM10010349_04990"
     CDS             complement(279..1160)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046139.1"
                     /locus_tag="IE274_RS02500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_04990"
                     /product="acyl-CoA thioesterase II"
                     /protein_id="WP_190113841.1"
                     /transl_table=11
                     /translation="MSEELDSLLGLLDLERVEEEIFRGVSRTSLVPRVFGGQVAAQALV
                     AAGRTVPGERPAHSLHAYFLRPGDPGAPIVYTVDRIRDGRSFTTRRVVAVQHGQPIFHL
                     SASFQAYEEGLEHQDAMPPAPDPETLPTAADSLPRYEDVLGADVVRRLLEARAAVDLRY
                     VDEPPFASVGAPRQARSQVWFRTNGKLGAEPAGSLLHLCLATYVSDMTLLDSVLLAHGR
                     GGWAVGDVVGASLDHAMWFHRPFRADEWLLYDQESPSSGGGRGLGQGRIWTRDGKLAVT
                     VIQEGVVRVPRD"
     gene            complement(1168..2325)
                     /locus_tag="IE274_RS02505"
                     /old_locus_tag="GCM10010349_05000"
     CDS             complement(1168..2325)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969014.1"
                     /locus_tag="IE274_RS02505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05000"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_190114107.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.4e-32, bitscore:
                     106.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.8e-26, bitscore:
                     86.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.6e-46, bitscore:
                     152.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTVFNEDHEAFRETVRAFIEAEVVPVYDEWFAAGQAPRDFYYK
                     LGELGVFGIRVPEEFGGAGIDSHKFEAVMYEETARAGVSFGGSGVHVLLGLPYIEMLAT
                     DEQKKRFLPKFVSGEEMWALAMTEPGTGSDVAGMKTTAKLSADGTHYVLNGAKTFITGG
                     VHADRVIVCARTSAPREDDRRFGISLFAVDTKSAGYSVGRKLDKLGLKVSDTAELAFVD
                     VEVPVDDLLGEENKGFHYLGHNLASERWGIAFGAYAQAKAAVRFAKEYVQERAVFGKPV
                     ASFQNTKFELAACQAEVDAAEAVADRALEALDAGELTPAEAASAKLFCTEVAHRVIDRC
                     LQLHGGYGFMNEYPIARLYADNRVNRIYGGTSEVMKMIIAKSMGL"
     gene            complement(2510..3106)
                     /locus_tag="IE274_RS02510"
                     /old_locus_tag="GCM10010349_05010"
     CDS             complement(2510..3106)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005486483.1"
                     /locus_tag="IE274_RS02510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05010"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190113842.1"
                     /transl_table=11
                     /translation="MATRTDAPTRREQILKEAARLFAERGFHGVGVDEIGAAVGISGPG
                     LYRHFAGKDAMLAELLVGISEQLLRGGERRAAEAAGSPGAVLDSLVEGHIDFALDDRPL
                     ITLHDRELDRLRDSDRKLVRSLQRRYVELWVSAVREVYAGLAEAEARASVHAVFGLLNS
                     TPHLGRPGSLPDREAMADLLNRLAHGALAAAAEGG"
     misc_feature    complement(3106..3119)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.06"
                     /tool="antismash"
     gene            3190..4806
                     /locus_tag="IE274_RS02515"
                     /old_locus_tag="GCM10010349_05020"
     CDS             3190..4806
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660219.1"
                     /locus_tag="IE274_RS02515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05020"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_190113843.1"
                     /transl_table=11
                     /translation="MQQAPVLASAADPASEAWRSNETAHRALAEELRGKLAAARLGGGE
                     RARQRHVARGKLLPRDRVDALLDPGSPFLELAPLAADGMYDGAAPAAGVIAGVGRVSGR
                     DCVIVANDATVKGGTYYPMTVKKHLRAQEIALENRLPCLYLVDSGGAFLPMQDEVFPDR
                     EHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLV
                     KAATGEVVTAEELGGGEVHSRVSGVTDHLAEDDPHALRIVRTIVSTLPARGQLPWEVRP
                     VEEPKVDPLGLYGAVPVDSRTPYDVREVIARVVDGSRFAEFKSEYGQTLVTGFAHIHGH
                     PVGIVANNGILFSESAQKGAHFIELCDQRGIPLVFLQNISGFMVGRDYEAGGIAKHGAK
                     MVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLA
                     TVKRDQLEARGEEWSAEDEDAFKAPVRAQYEQQGNAYYATARLWDDGVIDPLETRQVLG
                     LALTACAGAPLGERGFGVFRM"
     gene            4826..6916
                     /locus_tag="IE274_RS02520"
                     /old_locus_tag="GCM10010349_05030"
     CDS             4826..6916
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986681.1"
                     /locus_tag="IE274_RS02520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05030"
                     /product="biotin carboxylase N-terminal domain-containing
                     protein"
                     /protein_id="WP_190114108.1"
                     /sec_met_domain="ATP-grasp (E-value: 1.2e-07, bitscore:
                     27.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDTVLVANRGEIAVRVIRTLRTLGVRSVAVFSDADADARHVREA
                     DTAVRLGPAPAAESYLSAERLLAAAAASGAQAVHPGYGFLAENAAFAAACADAGLAFIG
                     PPAAAIDLMGDKIRAKETVRKAGVPVVPGSSGSGLTDAQLIDAAREIGTPVLLKPSAGG
                     GGKGMRLVRDAALLGDEIAAARREARASFGDDTLLVERWVDRPRHIEIQVLADAHGNVV
                     HLGERECSLQRRHQKIIEEAPSVLLDEATRAAMGSAAVEAARSCGYVGAGTVEFIVPGD
                     DPASYYFMEMNTRLQVEHPVTELVVSVDPAAAGGGLDLVEWQLRVASGEPLPFAQDDIT
                     LTGHAVEARICAEDPSRGFLPSGGTVLALHEPSGDGVRTDSGLSEGTEVGSLYDPMLSK
                     VIAYGPDRATALRKLRGALAETVTLGVPTNAGFLRRLLAHPAVVAGDIDTGLVEREAEN
                     LVDPDVPAEVYLAAALVRVRRAHPSRPAGRLPTTTAAAGWLDPFSVPNGWRLGGEAAWT
                     VHHLRVPGHEPVVVRTRPGAEGIEIQLPSGETAWGPGGLPPVSGRGGLGEPPAGPTTVT
                     LHHQDRTHTFHHAGDWLGQDGHAWHVQDHDPVEAALSGAAHTGLDALTAPMPGTVTVVK
                     VATGDEVTAGQSLLVVEAMKMEHVISAPHAGTVTELDVTPGTTVAMDQVLAVVTPAEED
                     AS"
     gene            6913..7923
                     /locus_tag="IE274_RS02525"
                     /old_locus_tag="GCM10010349_05040"
     CDS             6913..7923
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980522.1"
                     /locus_tag="IE274_RS02525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05040"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_190113844.1"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-50, bitscore:
                     167.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEASGGTAARGSAPANALPMVVPTEDLPPRVRIHEVGARDGLQ
                     NEKATVPTEVKAEFIHRLAAAGLTTIEATSFVHPKWVPQLADAEDLFPLLGDLRETQGT
                     HLPVLVPNARGLDRALALGARRVAVFASATESFAKANLNRTVDEALAMFEPVVARAKAA
                     ESAHDQVHVRGYLSMCFGDPWEGAVPIAQVARVCRALIDMGCDELSLGDTIGVATPGHV
                     QELLATLNEQGMPTHRIGVHFHDTYGQALSNTLAALQHGVTTVDASAGGLGGCPFAKSA
                     TGNLATEDLVWMLHGLGIETGVDLGRLTATSVWMAGQLGRPSPSRTVRALSHQEQ"
     gene            7929..9089
                     /locus_tag="IE274_RS02530"
                     /old_locus_tag="GCM10010349_05050"
     CDS             7929..9089
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325537.1"
                     /locus_tag="IE274_RS02530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05050"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_190113845.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 7.1e-39, bitscore:
                     128.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.8e-22, bitscore:
                     74.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.5e-50, bitscore:
                     165.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHHLSPEHEELRRTVEAFAHDVVAPKIGDLYERHEFPYEIVREM
                     GRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPLHLFGTE
                     EQKREWLPRLCSGEMLGAFGLTEPDGGSDAGGTRTTARLDEATDEWVINGTKCFITNSG
                     TDITGLVTVTAVTGRTDAGKPLISSIIVPSGTPGFTVAAPYSKVGWNSSDTRELSFADV
                     RVPRANLLGEIGRGYAQFLRILDEGRIAIAALGTGLAQGCVDESVKYAKERHAFGRPIG
                     SNQAIQFKIADMEMKAHTARLTWRDAASRLVSGEPFKKEAALAKLYSSTVAVDNAREAT
                     QIHGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGLTG"
     misc_feature    9195..9213
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 25.73"
                     /tool="antismash"
     misc_feature    complement(9200..9218)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.56"
                     /tool="antismash"
     gene            9256..10299
                     /locus_tag="IE274_RS02535"
                     /old_locus_tag="GCM10010349_05060"
     CDS             9256..10299
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006140622.1"
                     /locus_tag="IE274_RS02535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05060"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_190113846.1"
                     /transl_table=11
                     /translation="MSHSLRTPSRRGILAAGGALGLTAVLAACGDEKKDKSGSGSGTED
                     GGPWSFKDDRGKTAKTDATPANIVAFTGVAAALYDYGIEVKGVFGPTKTKDGKPDVQAG
                     DMDISKLTILGNAWDQFNIEKYVGLQPDVLISTMFDDKGTLWYVPEQSKDKILGLAPSV
                     GVSVYDRQLAKPLERILALAESLGADVKSDKVVTAKKRFEAASERLRKAAKSRPEIKVL
                     VGSASAEIFYVSGSDLSADLEYFKALGVHLVEPPENAKKESGGWFQNLSWENVDTYKAD
                     VIMMDNRTSALQPADLAKQKPTWGKLPAVKAGQVIPRVTEPIFSYAKCAPILEDLAKAI
                     EKAKKVS"
     misc_feature    10514..10534
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.91"
                     /tool="antismash"
     misc_feature    10518..10536
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 34.36"
                     /tool="antismash"
     gene            10618..12060
                     /locus_tag="IE274_RS02540"
                     /old_locus_tag="GCM10010349_05070"
     CDS             10618..12060
                     /NRPS_PKS="Domain: Aminotran_5 (141-265). E-value: 4.1e-10.
                     Score: 31.0. Matches aSDomain:
                     nrpspksdomains_IE274_RS02540_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382223.1"
                     /locus_tag="IE274_RS02540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05070"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_190113847.1"
                     /sec_met_domain="Aminotran_5 (E-value: 4.4e-08, bitscore:
                     27.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSHLLNDTTTESYRASVTEGVERVAARIATTSRPFTGVSADALT
                     PRVAAVDLDTPLHDTGAALDELDELYLRDAVYFHHPRYLAHLNCPVVIPAVLGEAVLSA
                     VNSSLDTWDQSAGGTLIERRLIDWTTERIGLGPAADGVFTSGGTQSNLQALLLAREEAK
                     TDSPARLRILASEVGHFSVQKAAKMLGLGQDAVVVIPTDRTKRMQTVALARELARLDAE
                     GLVPMAVVATAGTTDFGSIDPLPQIADLCAQYETWLHVDAAYGCGLLASRTRRDLLEGI
                     ERADSVTVDYHKSFFQPVSSSALLVRDAATLRHATYHAEYLNPRRAVQERIPNQVDKSL
                     QTTRRFDALKLWMTLRVMGADAIGDLFDEVCALADEGFDLLAADPRFDVVVQPQLSTLV
                     FRYIPAAICDPTAIDRANLYARKALFASGAAVVAGTKVGERQYLKFTLLNPETTAADIA
                     AVLDLIAGHAEQYLGENLDRAS"
     aSDomain        11041..11412
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE274_RS02540_Aminotran_5.1"
                     /evalue="4.10E-10"
                     /label="IE274_RS02540_Aminotran_5.1"
                     /locus_tag="IE274_RS02540"
                     /protein_end="265"
                     /protein_start="141"
                     /score="31.0"
                     /tool="antismash"
                     /translation="VFTSGGTQSNLQALLLAREEAKTDSPARLRILASEVGHFSVQKAA
                     KMLGLGQDAVVVIPTDRTKRMQTVALARELARLDAEGLVPMAVVATAGTTDFGSIDPLP
                     QIADLCAQYETWLHVDAAYG"
     gene            12125..13360
                     /locus_tag="IE274_RS02545"
                     /old_locus_tag="GCM10010349_05080"
     CDS             12125..13360
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544962.1"
                     /locus_tag="IE274_RS02545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05080"
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_190114109.1"
                     /transl_table=11
                     /translation="MGIGLGPFNLGLACLTEPLDDLNGLFLESKPDFEWHSGMFLDGAH
                     LQTPFMSDLVTLADPTSPYSFLNFLKESGRLYSFYIRENFYPLRREYNDYCRWAAGKLS
                     SVRFGTTVTRVTYDNGLYFITTGSGDTFRARHLVLGTGTPPHIPEACRGLGGDFLHNSR
                     YLEHKEELQKKNSLTIVGSGQSAAEIYYDLLADMDTHGYRLNWVTRSPRFFPLEYTKLT
                     LEMTSPEYIDYFHALPEDTRYRLESEQRSLFKGIDGELIDAIFDLLYQKNLDGPVPTRL
                     VTNASLRKARYTHGVYTLGLRQEEQGKDFEVTTEGLILATGYRYAVPAFLEPLRAHLRF
                     DGHGRFDVARNYSVDDSGRGVFLQNAAVHTHSMTSPDLGMGPYRNAYIIRELLGREVYP
                     VEKSIAFQEFAV"
     gene            13402..14004
                     /locus_tag="IE274_RS02550"
                     /old_locus_tag="GCM10010349_05090"
     CDS             13402..14004
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639539.1"
                     /locus_tag="IE274_RS02550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05090"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190114110.1"
                     /transl_table=11
                     /translation="MRRTPSRDRGVGTLAMRPLDPFEDTELVHSWVTHPKSAFWLLQDA
                     RLQDIEREYMAIAASEHHDAFVGLHDGEPAFLMERYDPRYIELVGLYEPEPGDVGMHFL
                     VAPTDRPVHGFTRAVIATVMEHLFADPRTHRVVVEPDVTNTAVHRLNEEVGFVPEREID
                     KPEKRALLSFCTRESYDAAVVRHAVATRPTAVSGART"
     gene            14001..15830
                     /locus_tag="IE274_RS02555"
                     /old_locus_tag="GCM10010349_05100"
     CDS             14001..15830
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639540.1"
                     /locus_tag="IE274_RS02555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05100"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_229909103.1"
                     /sec_met_domain="IucA_IucC (E-value: 8.8e-78, bitscore:
                     256.7, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTPAAPLSPAAPRTPLSALSPQARAVDHLNPERWAEANRLLIR
                     KALAEFAHERLLTPEDLGAGRYVVRSDDGLTRYRFAARVFALDHWAVDAASLTRHRDGV
                     ELPLNALEFFTELRGTLGLSEKVLPVYLEEISSTLSGTCFKLAKPHVSAADLVTAGFQE
                     IETGMTEGHPCFVANNGRLGFGVHEYLSYAPETASPVRLIWLAARRDRAAFTAGEGLEY
                     ESFLRAELGRETLDRFDAVLRAQDLDPADYLLIPAHPWQWWNKLSVTFAAEIADRRLVC
                     LGEGDDEYLAQQSIRTFFNASAPAKHYVKTALSVINMGFMRGLSAAYMKATPAINDWLH
                     GLVASDEVLRSTGLGIIRERAAVGYRHLEYEAATDRYSPYRKMLAALWRESPVPALKDG
                     ESLATMASLLHTDRDGASFAGALMQRSGLAPAEWLRRYLRAYLTPLLHCFYAYDLVFMP
                     HGENVIMVLKDGVVDRVLFKDIAEEIAVMDPAAVLPPEVERIRVDVPEDRKLLSILTDV
                     FDCFFRFLSASLVTEGLLDEDVFWRTVAECVRDYQHSMPELADRFRQYDMFAPEFALSC
                     LNRLQLRDNEQMLDLADPAGALQLIGTLKNPIA"
     gene            complement(15906..17519)
                     /locus_tag="IE274_RS02560"
                     /old_locus_tag="GCM10010349_05110"
     CDS             complement(15906..17519)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065773.1"
                     /locus_tag="IE274_RS02560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05110"
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="WP_190113848.1"
                     /transl_table=11
                     /translation="MRQHHRTACVIGSLLLIAAAGTSSSAAAPGPAPDRAEPVPLGRVV
                     PVPLQAEPGGSAFEITSKTRIRVGDRPEERRVGEYLAGVLRPSTGYRLPVTDRGGGDAI
                     RLRISAEPANRALGDEGYRVISKRGSLTITSRSSAGLFYGVQTVRQQLPAAAERKTKQP
                     GPWLIAGGTIKDKPRYAYRGSMLDVSRHFFPVEHVKRYIDQMVLYKMNKLHLHLSDDQG
                     WRIAIDSWPRLATYGGSTQVGGGPGGHYTKAQYKEIVAYAASRQMEVVPEIDMPGHTNA
                     ALASYAELNCDGVAPPLYTGTNVGFSSLCVKKDVTYKFVADVVRELSALTPGGSVHIGG
                     DEAHSTSHEDFVTFMGKVQPLVTKYGKNVMGWHQLAGANPVQGAVAQYWGYDRTGQAER
                     DQVVNAAKKGTKLVLSPADRAYLDMKYDKDTPLGLSWAGYVEVQRSYDWDPGTYLQGAP
                     ADAVLGVEAPLWTETLSTPAQLDYMAFPRLPGIAELGWSPASTHDWNTYRTRLAEQAPR
                     WDALGITYYKSPQVPWPGKR"
     misc_feature    complement(17470..17484)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     misc_feature    17600..17615
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.31"
                     /tool="antismash"
     gene            17646..18542
                     /locus_tag="IE274_RS02565"
                     /old_locus_tag="GCM10010349_05120"
     CDS             17646..18542
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005486503.1"
                     /locus_tag="IE274_RS02565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05120"
                     /product="DUF4429 domain-containing protein"
                     /protein_id="WP_190113849.1"
                     /transl_table=11
                     /translation="MAEIIQRDGTWTFDGETLRLVPGRDKAVSLLRKTLGELTVPLTAL
                     AGIAFEQGKKSGRLRLRLRDGADPLLQATGGKLTDASDPYQLTVEPDRYGVAEYVVDEV
                     RNALLLEQVPAKRCESYLLSGPSVPLQVAAGDATVSFDGEHVRLEWNWKTEEAKAASGT
                     RSIDLADVAAVEWQPAIGLENGYLRFTVKNAPTKAPPKYDPNSVELWGFKKDPLMALVA
                     AAVQARLPHPATPAKAALAEDAPAASDAPAALPAAPAEDSHDALLRRLRELGELHQSGI
                     LTDEEFAAAKQAVLKRM"
     gene            18641..18898
                     /locus_tag="IE274_RS02570"
                     /old_locus_tag="GCM10010349_05130"
     CDS             18641..18898
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131788.1"
                     /locus_tag="IE274_RS02570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05130"
                     /product="hypothetical protein"
                     /protein_id="WP_190113850.1"
                     /transl_table=11
                     /translation="MHEELVDHLTRSTQLHRGEALRVIQDVLAYFDETTEAFVRRRHRE
                     LQGQGLVNTEIFERIAADLRYRAVAPPELTLRQLRRVVYG"
     gene            18929..20746
                     /gene="glmS"
                     /locus_tag="IE274_RS02575"
                     /old_locus_tag="GCM10010349_05140"
     CDS             18929..20746
                     /EC_number="2.6.1.16"
                     /GO_function="GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA]"
                     /GO_process="GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980526.1"
                     /locus_tag="IE274_RS02575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05140"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="WP_190113851.1"
                     /sec_met_domain="GATase_7 (E-value: 1.9e-18, bitscore:
                     62.1, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGKRDVAPLLLEGLQRLEYRGYDSAGVVITSPKATGLK
                     MVKAKGRVRDLEARVPKRFTGTTGIAHTRWATHGAPSDENAHPHLDGENKVAVVHNGII
                     DNASELRAKLTADGVEFRSETDTEVITHLIARSTAEKLEDRVREALRHIEGTYGIAVLH
                     ADFNDRIVVARNGSPVVLGIGEKEMFVASDVAALVSHTRQVVTLDDGEMATIKADDYRT
                     YTTEGSRTSAEPTTVEWEAESYDMGGHDTYMHKEIFEQPDAVDRVLRGRIDDRFATVHL
                     GGLNLDAHDARKVRRVKILGCGTSYHAGMIGAQMIEELARIPADAEPASEFRYRNAVVD
                     PDTLYVAVSQSGETYDVLAAVQELKRKGARVFGVVNVVGSAIAREADAGVYVHAGPEVC
                     VVSTKCFTNTTVAFALLALHLGRIRDLSASDGKRIIAGLRQLPAQIEQMLAREDEIKKL
                     AEEYADARSMLFIGRVRGYPVAREASLKLKEISYIHAEAYPASELKHGPLALIEPALPT
                     VAIVPDDDLLEKNRAALEEIKARSGKILAVAHQEQEKADHTIVVPKNEDELDPILMGIP
                     LQLLAYHTALVLGRDIDKPRNLAKSVTVE"
     misc_feature    complement(18950..18964)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(21153..21677)
                     /locus_tag="IE274_RS02580"
                     /old_locus_tag="GCM10010349_05150"
     CDS             complement(21153..21677)
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325548.1"
                     /locus_tag="IE274_RS02580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05150"
                     /product="universal stress protein"
                     /protein_id="WP_030360002.1"
                     /transl_table=11
                     /translation="MAGHEFSEPANRKRQVADPSATPQAAEEPRHSCDPAFRHGVVVGF
                     DGSTSSERALAYAIGMAHRSGSGLIIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLGL
                     ELACAEYLSEVPWILVERGGDICHELEEVGREYSADAIVVGSTHGIVGRIFGSVAGRLA
                     RRAQRPVVVIP"
     misc_feature    21958..21973
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.18"
                     /tool="antismash"
     gene            22209..22622
                     /locus_tag="IE274_RS40285"
                     /old_locus_tag="GCM10010349_05160"
     CDS             22209..22622
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005486513.1"
                     /locus_tag="IE274_RS40285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05160"
                     /product="hypothetical protein"
                     /protein_id="WP_372447240.1"
                     /transl_table=11
                     /translation="MPGPSTAAPVVAATTRRRAPEGARERRAPSVPTPRPARTPAPAPQ
                     EAASDVVRWAAFSCVLVPVVLVGYGTSLAGAGGAALGLAAVTGVCRVLLQQSERGAARA
                     RAQRGAGTRGRRQRQAPGAHRGGRRPGPDAPVD"
     misc_feature    22647..22661
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.48"
                     /tool="antismash"
     misc_feature    complement(22685..22700)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.51"
                     /tool="antismash"
     misc_feature    22800..22813
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    22867..22882
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            23019..24335
                     /locus_tag="IE274_RS02590"
                     /old_locus_tag="GCM10010349_05170"
     CDS             23019..24335
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641052.1"
                     /locus_tag="IE274_RS02590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05170"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190113852.1"
                     /transl_table=11
                     /translation="MSHDSTAVQEAAARKLSGRRRREIVAVLLFSGGPIFESSIPLSVF
                     GIDRQDAGVPRYRLLVCAGEEGPLRTTGGLELTAPHGLEAISRAGTVVVPAWRSITSPP
                     PLEALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVD
                     PRELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGNEAAGALARRLVVPPRRAGGQERYLD
                     RSLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWL
                     ITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRAAYRARRPQ
                     NERSLESASAPSAAPAASGATAAAAMATGPSVVATDGPGPGPGGNPGLTPGPVPSQTRR
                     TAAASSLGAAASLPMDPGKPHSDAYAPGRTPLPGQRSAP"
     misc_feature    23427..23429
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            24346..24948
                     /gene="orn"
                     /locus_tag="IE274_RS02595"
                     /old_locus_tag="GCM10010349_05180"
     CDS             24346..24948
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="orn"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641051.1"
                     /locus_tag="IE274_RS02595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05180"
                     /product="oligoribonuclease"
                     /protein_id="WP_190113853.1"
                     /transl_table=11
                     /translation="MNDRMVWIDCEMTGLSLTDDALIEVAALVTDSELNVLGEGVDIVI
                     RPPDAALETMPEVVRQMHTTSGLLDELAGGTTLADAEEQVIAYIRQHVKEPRKAPLCGN
                     SVGTDRGFLLRDMPTLEDFLHYRIVDVSSIKELARRWYPRAYFNSPDKNGNHRALADIR
                     ESIAELRYYREAIFVPQPGPDSDTAKSIAAKHVLPAD"
     tRNA            25060..25132
                     /anticodon=(pos:631964..631966,aa:His,seq:gtg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IE274_RS02600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10010349_t00100"
                     /product="tRNA-His"
     gene            25060..25132
                     /locus_tag="IE274_RS02600"
                     /old_locus_tag="GCM10010349_t00100"
     gene            complement(25218..25631)
                     /locus_tag="IE274_RS02605"
                     /old_locus_tag="GCM10010349_05190"
     CDS             complement(25218..25631)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038353.1"
                     /locus_tag="IE274_RS02605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05190"
                     /product="FxLYD domain-containing protein"
                     /protein_id="WP_190113854.1"
                     /transl_table=11
                     /translation="MLLYVVLMAVALMAILVAVALIGGSDEETPPGRSPSQEQTAPPVS
                     GPRADVEIIKCSVEPNTRWPNAELRITNHSSKTSDYWVEVEFVDADGVRIAEGVAGTSN
                     LAPDQVANESASGFREASGKVVCRITDVTRHAS"
     misc_feature    complement(25709..25719)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(25823..26878)
                     /locus_tag="IE274_RS02610"
                     /old_locus_tag="GCM10010349_05200"
     CDS             complement(25823..26878)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660189.1"
                     /locus_tag="IE274_RS02610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05200"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_190113855.1"
                     /transl_table=11
                     /translation="MGSGQPRGRGGARPTLEQVAARAGVGRGTVSRVINGSPRVSEHTR
                     AAVEEAVAELGYVPNTAARALAANRTDSIAVVVPEPESRFFAEPYFSDIIHGVGAALAE
                     TDMQLLLTFAGGDRERRSLAQYLSAHRVDGVLLVSVHADDPLPDLLRQLGIPAVISGRR
                     SADEPLASVDSDNFAGARAAVGHLLDRGRRTIATITGRLDVYGAQRRLDGYRDALTEAG
                     HPVEESLIARGDFTEDGGRRAMTELLARRPDLDAVFAGSDVMAAGARQVLREVGRRIPD
                     DVALVGFDDSAIARHMDPPLTSVRQPITEMGRTMTDVLLAEIADTRPAGTRHLARQQIV
                     LPTELVCRASS"
     misc_feature    complement(27010..27024)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     misc_feature    27011..27025
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     gene            27139..28476
                     /locus_tag="IE274_RS02615"
                     /old_locus_tag="GCM10010349_05210"
     CDS             27139..28476
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717689.1"
                     /locus_tag="IE274_RS02615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05210"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_190113856.1"
                     /transl_table=11
                     /translation="MRYRTRTSRTAVVLAAVTTLAAGLLAGCAEDSDEDEPGGSSGGGG
                     GGKGKTTLTVGVFGAFGLQEAGLYDEYEKLNPDINIKQNSVQRNENYWPALLTHLSSGS
                     GLSDVQAVEVGNIAELTGTHASKLVDLGKTSGVDKNAYLDWKWQQGTTDDGKTIGLGTD
                     IGPTGICYRKDLFKKAGLPTDREAVGKLWAGDWSKYLDAGKRYQKKAPKGTAFVDGATG
                     VMAAVHASGKEKFYDAEGELIYQDSAGVQEGWDLAAQFAEAGLTAKLQQFQPSWDQAFS
                     NGSFATVTCPPWMLGYIKDKAGDKGEDQWDVAAAPKPGNWGGSFLTVPEAGKNKEEAAK
                     LVAWLTAPKQQAKLFDKRASFPSAEAAYGLPEVKDAKNPYFGDAPVGQVFAKAAEGVPV
                     QPIGPKDGIISQYLADTGMLGVDQKGTSPDKAWDKAVKTIDNALDQ"
     gene            28484..29509
                     /locus_tag="IE274_RS02620"
                     /old_locus_tag="GCM10010349_05220"
     CDS             28484..29509
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949795.1"
                     /locus_tag="IE274_RS02620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010349_05220"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_229909104.1"
                     /transl_table=11
                     /translation="MTDIPSDTRTAAPSTGEEGAAPRARAVAALDPAAERRRARRSRRY
                     RWDMKWSPYALIAPFFLFFIAFGLFPLLYTGWASLHRVELGTPTDMEWVGLRNFSRLLE
                     DDFFWNALRNTFTIGIISTVPQLVMALGIAHLLHYRLRGSMFFRVAILTPYATSVAAAT
                     LVFVLMFSRTDHGMINWALGLIGVDAVDWQNGDWTAQFAVSSIVIWRWTGYNALIYLAA
                     MQAIPNDLYESAALDGASRWQQFRHVTIPSLRPTILFTCVVSTIGATQLFGEPLLFSQG
                     ASPTGGSDHQFQTLGLYLYEQGWFNQHLGRSSAIAWTMFLILVLIGLVNWAISRWIRRS
                     A"
     misc_feature    complement(29529..29538)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.67"
                     /tool="antismash"
ORIGIN
        1 cgggcgccgc cgtagccgag cggatggtcc tcgtcggcgg ggcgccgcgc gctccgcagc
       61 gagacgagca gcatcagctc cgtgacggtg tcggccacgg agtgcgccgc ctccgacagc
      121 atcgcgctgg atccgctgag caccccggcg gcggccttgg cgacggcgat gccgaggttg
      181 gcgagggcgg cgacgagaac ggtgacggtg ctttcggctg cgggttcacc catggtgggg
      241 cagtatgccg gaattatgac cgcggagcgg ccgggatctc agtcccgggg aacccggacc
      301 acaccctcct ggatcaccgt cacggccagc ttcccgtccc tcgtccagat ccgcccctgg
      361 ccgaggccgc gcccgccccc ggacgacggg gactcctggt cgtagaggag ccactcgtcc
      421 gcccggaacg gccggtggaa ccacatggcg tggtcgagcg aggcgccgac gacgtccccg
      481 acggcccacc cgccgcgccc gtgggcgagc aggacggagt cgaggagcgt catgtcggag
      541 acgtacgtgg cgaggcagag gtgcaggagg gagcccgcgg gctccgcgcc cagcttgccg
      601 ttggtgcgga accagacctg ggaccgcgcc tgccggggcg cgccgacgct ggcgaacggc
      661 ggctcgtcca cgtaccgcag gtcgacggcg gcccgcgctt cgaggagccg ccgcacgacg
      721 tcggctccga gcacgtcctc gtaccggggc agcgaatccg cggcggtggg cagcgtctcc
      781 gggtcgggcg cgggcggcat cgcgtcctgg tgctccaggc cctcctcgta cgcctggaac
      841 gacgcggaga ggtggaagat cggctgcccg tgctgcacgg cgacgacgcg gcgcgtggtg
      901 aaggagcgcc cgtcgcggat gcggtcgacg gtgtagacga tgggcgcgcc cgggtcgccg
      961 gggcgcagga agtaggcgtg cagggagtgc gcgggccgtt cgccggggac cgtgcgcccg
     1021 gcggcgacga gggcctgcgc ggcgacctgg ccgccgaaga cgcgcggcac cagcgacgtc
     1081 cggctgacgc cgcggaagat ctcctcctcg acccgttcca ggtcgaggag gccgagcagg
     1141 ctgtcgagtt cctcgctcat cggcgagtta cagacccatc gacttcgcga tgatcatctt
     1201 catgacctcg ctggtgccgc cgtagatgcg gttgacgcgg ttgtccgcgt acaggcgggc
     1261 gatcgggtac tcgttcatga agccgtagcc gccgtgcagc tggaggcagc ggtcgatgac
     1321 gcggtgcgcg acctcggtgc agaacagctt cgcggaggcg gcctcggcgg gggtcagctc
     1381 gcccgcgtcc agggcctcca gggcgcggtc ggcgacggcc tcggcggcgt ccacctcggc
     1441 ctggcaggcg gccagttcga acttggtgtt ctggaacgag gcgaccggct tgccgaagac
     1501 ggcccgctcc tggacgtact ccttggcgaa ccgcacggcc gccttggcct gcgcgtacgc
     1561 gccgaaggcg atgccccagc gctcggaggc gaggttgtgg ccgaggtagt ggaagccctt
     1621 gttctcctcg ccgagcaggt cgtcgacggg gacctcgacg tccacgaagg ccagttcggc
     1681 ggtgtcggag accttcaggc cgagcttgtc gagcttgcgg ccgacggagt agcccgcgga
     1741 cttggtgtcg acggcgaaga gcgagatgcc gaagcggcgg tcgtcctcgc gcggggcgga
     1801 ggtgcgggcg cagacgatca cgcggtcggc gtgcacgccg ccggtgatga aggtcttggc
     1861 gccgttgagg acgtagtgcg tgccgtcggc ggagagcttg gcggtggtct tcatgcccgc
     1921 gacgtcggag ccggtgccgg gctcggtcat ggcgagcgcc cacatctcct cgccggagac
     1981 gaacttgggc aggaagcgct tcttctgctc gtcggtggcg agcatctcga tgtacggcag
     2041 gccgagcagg acgtgcacgc cggagccgcc gaaggagacg cccgcgcggg ccgtctcctc
     2101 gtacatgacc gcctcgaact tgtgcgagtc gatgcccgcg ccgccgaact cctcggggac
     2161 gcggatgccg aagacgccga gctcgccgag cttgtagtag aagtcccggg gcgcctggcc
     2221 cgccgcgaac cactcgtcgt agaccgggac gacctcggcc tcgatgaagg cccggacggt
     2281 ttcccggaat gcctcgtggt cctcgttgaa gacggtacgc cgcacgactg ctccctgggt
     2341 cacggatccg actaagcgct tgctcatcct gaggttaccg gtgagttccg gtgaccgtcc
     2401 agggcacaat ccgtgaccgt cggccaccgc gcccttgatc gcggcccgcg gcccggcccg
     2461 ccctcaaacg ccggacgggc ttgttcccct cccccgaccg tcggggggtt cagccccctt
     2521 cggccgccgc cgccagcgcc ccgtgcgcca agcggttcag cagatccgcc atcgcctccc
     2581 ggtccggcag cgaacccggg cggcccaggt gcggcgtcga gttcaggagg ccgaacaccg
     2641 cgtgcaccga cgcccgcgcc tccgcctcgg cgagcccggc gtacacctcc cgcaccgcgg
     2701 aaacccacag ctcgacgtac cgccgttgca gcgagcggac cagtttgcgg tcgctgtccc
     2761 gcaggcggtc cagctcgcgg tcgtggagag tgatcagcgg gcggtcgtcg agggcgaagt
     2821 cgatgtgacc ctcgacgagc gagtcgagca cggcgccggg cgaccccgcg gcctccgcgg
     2881 cccggcgttc gccgccccgc agcagctgct cgctgatgcc cacgaggagt tcggccagca
     2941 tcgcgtcctt gcccgcgaag tggcggtaga ggccgggccc gctgatgccg acggcggccc
     3001 ctatctcgtc cacgccgacg ccgtggaagc cgcgctcggc gaacagccgg gcggcttcct
     3061 tgaggatctg ctcgcggcgg gtgggggcgt cggtcctggt ggccatggaa acaattctag
     3121 acagcacggt tagcggtcgt taaccttggc gacatacgtt aacgctcact aacagcggga
     3181 gcacagcgga tgcaacaggc accagtcctc gcgagcgcgg cggaccccgc ctcggaagcc
     3241 tggcggtcga acgagacggc gcaccgcgcc ctggccgagg agctgcgcgg caaactcgcg
     3301 gcggcccggc tcggcggcgg cgagcgtgcc cggcagcggc acgtggcgcg cggcaagctg
     3361 ctgccgcgcg accgcgtgga cgccctcctc gaccccggct cgccgttcct cgaactggcc
     3421 ccgctcgcgg ctgacgggat gtacgacggg gcggccccgg ccgccggcgt catcgcgggt
     3481 gtcggccggg tcagcgggcg cgactgcgtc atcgtcgcca acgacgccac cgtcaagggc
     3541 gggacgtact acccgatgac ggtcaagaag cacctgcggg cgcaggagat cgccctggag
     3601 aaccggctcc cctgcctgta cctggtggac tcgggcggcg ccttcctgcc gatgcaggac
     3661 gaggtgttcc ccgaccggga gcacttcggg cggatcttct acaaccaggc gcggatgtcg
     3721 ggcgcgggca tcccgcagat cgcggcggtc ctcggctcct gcacggcggg cggcgcgtac
     3781 gtccccgcga tgagcgacga ggccgtgatc gtccgcaacc agggcacgat cttcctgggc
     3841 ggcccgcccc tggtgaaggc cgccaccggc gaggtcgtca ccgccgagga gctgggcggc
     3901 ggcgaggtgc actcccgggt gtcgggcgtc accgaccacc tcgcggagga cgacccgcac
     3961 gccctgcgca tcgtccgcac gatcgtctcg acgctccccg cgcgcgggca actgccctgg
     4021 gaggtccggc cggtcgagga gccgaaggtc gacccgctcg gcctgtacgg cgcggtgccg
     4081 gtggactccc gcactccgta cgacgtccgc gaggtcatcg cccgcgtcgt cgacggctcg
     4141 cgcttcgccg agttcaagtc cgagtacggc cagaccctgg tgaccggctt cgcgcacatc
     4201 cacggccacc cggtcgggat cgtcgcgaac aacggcatcc tgttctccga gtccgcccag
     4261 aagggcgccc acttcatcga gctgtgcgac cagcgcggca tcccgctggt gttcctgcag
     4321 aacatctccg gcttcatggt gggccgggac tacgaggccg ggggcatcgc caagcacggc
     4381 gcgaagatgg tcacggccgt ggcctgcacc cgtgtcccga agctgacggt ggtggtcggc
     4441 ggatcgtacg gagcgggcaa ctactcgatg tgcggccggg cctattcacc gcgcttcctg
     4501 tggatgtggc ccaacgccaa gatctccgtg atgggcggcg agcaggccgc ctccgtcctc
     4561 gccaccgtca agcgcgacca gctcgaagcg cggggcgagg agtggtcggc cgaggacgag
     4621 gacgccttca aggccccggt ccgcgcgcag tacgaacagc agggcaacgc ctattacgcc
     4681 acggcacggc tgtgggacga cggtgtcatc gacccgttgg agacccgcca ggtgctcggc
     4741 ctggctctga ccgcgtgtgc cggggcgccc ttgggcgaac gcggcttcgg cgtcttccgg
     4801 atgtgaggga ccagacccca tgagcatgtt cgacacagtc ctggtggcca accggggcga
     4861 gatcgccgtc cgcgtcatcc gcacgctgcg gacgctcggc gtccgttcgg tggccgtctt
     4921 ctccgacgcc gacgccgacg cccggcacgt ccgcgaggcc gacacggcgg tgcggctcgg
     4981 gcccgccccg gccgccgaga gctatctgtc ggccgagcgg ctcctggccg ccgccgcggc
     5041 gtccggcgcc caggccgtcc accccggcta cggcttcctc gccgagaacg ccgccttcgc
     5101 ggcggcctgc gcggacgccg ggctcgcctt catcggaccg cccgccgccg ccatcgacct
     5161 gatgggcgac aagatccggg ccaaggagac ggtacggaag gccggggttc cggtcgtccc
     5221 cggctcctcg ggcagcggcc tcaccgacgc ccagctcatc gacgccgccc gggagatcgg
     5281 cacccccgtg ctgctcaagc cctccgcggg cggcggcggc aagggcatgc gcctggtccg
     5341 ggacgccgcc ctcctcggcg acgagatcgc cgccgcgcgc cgcgaggccc gcgcctcctt
     5401 cggcgacgac acgctgctcg tcgagcggtg ggtggaccgg ccccggcaca tcgagatcca
     5461 ggtcctcgcc gacgcccacg gcaacgtggt ccacctcggc gagcgcgagt gctccctcca
     5521 gcggcgccac cagaagatca tcgaggaggc gccgtccgtc ctcctcgacg aggcgacgcg
     5581 ggccgcgatg gggtccgccg ccgtggaggc cgcgcgctcc tgcgggtacg tcggcgcggg
     5641 cacggtcgag ttcatcgtcc cgggcgacga ccccgcctcg tactacttca tggagatgaa
     5701 cacccgcctc caggtcgagc accccgtcac ggagctggtc gtatccgttg atccggctgc
     5761 cgccgggggc gggctcgacc tggtcgaatg gcagctccgt gtcgcctccg gcgagccgct
     5821 gcccttcgcg caggacgaca tcaccctcac cgggcacgcc gtcgaggccc gcatctgcgc
     5881 cgaggaccct tcccgcggct tcctgccgtc cggcgggacc gtcctcgccc tgcacgagcc
     5941 gtccggcgac ggcgtgcgca ccgactccgg gctcagtgag ggcacggagg tcgggagcct
     6001 gtacgacccg atgctgtcga aggtgatcgc gtacgggccc gaccgggcga cggctctgcg
     6061 caagctgcgg ggcgcgctcg cggagacggt caccctgggg gtgccgacga acgcggggtt
     6121 cctgcggagg ctgttggccc atccggcggt ggtggccggg gacatcgaca ccggcctggt
     6181 cgaacgcgag gccgagaacc tggtggaccc ggacgtcccg gccgaggtct acctggctgc
     6241 cgcgttggtg cgggtccgtc gtgcccaccc gtcccgccct gcgggacgac tgcccacgac
     6301 gacggcggca gcaggatggc tggacccgtt ctccgtgccc aacggctggc ggctcggcgg
     6361 cgaagccgcg tggacggtgc accacttgcg cgtaccgggg cacgaaccgg tcgtcgtccg
     6421 cacccgcccc ggtgccgaag gcatcgagat ccagctcccc tccggggaga cggcctgggg
     6481 gcccgggggc ctgcccccgg tttcgggaag gggcgggctc ggggagcccc cggcagggcc
     6541 caccaccgtc accctccacc accaggaccg gacccacacc ttccaccacg ccggcgactg
     6601 gctcggccag gacggccacg cctggcacgt ccaggaccac gaccccgtgg aagccgccct
     6661 cagcggcgcg gcccatacgg gcctggacgc cctgacggcc ccgatgcccg gcaccgtcac
     6721 cgtcgtcaag gtggcgaccg gcgacgaggt gaccgcgggc cagagcctcc tggtcgtgga
     6781 ggcgatgaag atggagcacg tcatctccgc cccgcacgcg ggcaccgtca ccgaactgga
     6841 cgtcaccccg ggcaccacgg tcgccatgga ccaggtcctg gccgtggtga cccccgcgga
     6901 ggaggacgcg tcatgagcac cgaagcgagc ggcggcaccg cggcgcgcgg cagcgccccg
     6961 gcgaacgccc tccccatggt cgtccccacc gaggacctcc cgccccgcgt ccgcatccac
     7021 gaggtgggcg cgcgggacgg cctgcagaac gagaaggcga ccgtaccgac cgaggtgaag
     7081 gcggagttca tccaccgcct cgccgccgcg ggcctcacca cgatcgaggc gaccagcttc
     7141 gtgcacccca agtgggtgcc ccaactggcc gacgcggagg acctgttccc gctgctcggg
     7201 gacctgcgcg agacccaggg cacgcacctg cccgtcctgg tccccaacgc ccgcggcctc
     7261 gaccgcgccc tcgcgctcgg ggcccggcgc gtcgcggtgt tcgcgagcgc caccgagtcc
     7321 ttcgccaagg ccaacctgaa ccggacggtg gacgaggcgc tcgccatgtt cgagccggtg
     7381 gtggcgcggg cgaaggcggc ggagagcgcg cacgaccagg tgcacgtgcg cggctatctg
     7441 tcgatgtgct tcggcgaccc ctgggagggc gccgtgccca tcgcccaggt ggcgcgggtc
     7501 tgcagggcgc tgatcgacat gggctgcgac gagctgagcc tcggcgacac catcggcgtg
     7561 gcgacccccg gccacgtaca ggaactgctc gccaccctca acgagcaggg catgccgacg
     7621 caccgcatcg gtgtgcactt ccacgacacc tacggccagg cgctgtccaa caccctggcc
     7681 gccctgcagc acggggtgac caccgtggac gcctccgcgg gcggcctcgg cggctgcccg
     7741 ttcgcgaaga gcgccaccgg aaacctcgcc accgaagacc tcgtgtggat gcttcacggc
     7801 ctcggcatcg agaccggggt cgacctcggc cgtctcaccg ccaccagcgt gtggatggcc
     7861 ggccagttgg gccgaccgag cccgtcccgc accgtgcgtg ccctctccca ccaggagcag
     7921 tgagaacgat ggaccaccac ctctcccccg aacacgagga actgcggcgc accgtcgagg
     7981 cgttcgccca cgacgtggtc gccccgaaga tcggcgacct ctacgagcgg cacgagttcc
     8041 cgtacgagat cgtgcgcgag atgggccgca tgggcctctt cggcctgccc ttccccgagg
     8101 agtacggcgg catgggcggc gactacctgg cgctcggcat cgccctggag gaactggcgc
     8161 gcgtcgactc gtccgtggcg atcacgctgg aggcgggcgt atcgctcggt gccatgccgc
     8221 tgcacctctt cggcaccgag gagcagaagc gggagtggct gccgaggctg tgctccggcg
     8281 agatgctcgg cgccttcggc ctgaccgagc cggacggcgg ttcggacgcg ggcggtacgc
     8341 ggacgacggc gcgcctggac gaggcgaccg acgagtgggt catcaacggc acgaagtgct
     8401 tcatcaccaa ctccgggacc gacatcacgg gcctggtgac ggtgacggcg gtgacgggcc
     8461 gcacggacgc gggcaagccg ctgatctcct cgatcatcgt gccgtccggc accccgggct
     8521 tcacagtcgc ggcgccctac tcgaaggtcg gctggaactc ctcggacacc cgggagctgt
     8581 cgttcgccga cgtgcgggtg ccgcgggcga acctgctcgg cgagatcggg cgcggctacg
     8641 cgcagttcct gcggatcctg gacgaggggc ggatcgcgat cgcggccctg ggcacggggc
     8701 tcgcgcaggg gtgcgtcgac gagtcggtga agtacgccaa ggagcggcac gcgttcgggc
     8761 gccccatcgg ctcgaaccag gccatccagt tcaagatcgc cgacatggag atgaaggcgc
     8821 acacggcgcg gctcacctgg cgcgacgcgg cctcgcgcct cgtctcgggc gagccgttca
     8881 agaaggaggc ggcgctcgcg aagctgtact cgtcgacggt cgccgtcgac aacgcgcgcg
     8941 aggccacgca gatccacggc gggtacgggt tcatgaacga gtacccggtg gcgcggatgt
     9001 ggcgggactc caagatcctg gagatcggcg agggcacgag cgaggtgcag cgcatgctga
     9061 tcgcccggga gctgggcctc acgggctgag gccgggctcc cggcgagagc tccgcgaagg
     9121 ccctgcgagg gctgtgcggg gggggctgtg cgggtccggt gaggacccgg tgcggggggc
     9181 cactggaccg gaagcaaggt taggttaacc taagctcgac ttccggccag tgccccgtac
     9241 gaaagcagag acctcatgtc gcacagcctc cgcacgccct cgcgccgcgg catcctcgcc
     9301 gcgggcggcg ccctcgggct caccgccgtc ctcgccgcct gcggggacga gaagaaggac
     9361 aagagcggct cgggcagcgg caccgaggac ggcggcccct ggtccttcaa ggacgaccgg
     9421 ggcaagacgg ccaagacgga cgcgacgccc gcgaacatcg tggcgttcac cggcgtcgcc
     9481 gccgcgctgt acgactacgg catcgaggtc aagggcgtct tcggcccgac gaagaccaag
     9541 gacggcaagc cggacgtcca ggccggtgac atggacatca gcaagctgac gatcctcggc
     9601 aacgcctggg accagttcaa catcgagaag tacgtgggcc tccagccgga cgtcctcatc
     9661 tccacgatgt tcgacgacaa gggcaccctc tggtacgtgc ccgagcagtc caaggacaag
     9721 atcctggggc tcgccccgag cgtcggcgtc tccgtctacg accggcagct ggccaagccc
     9781 ctggagcgca tcctcgccct cgccgagtcg ctcggcgcgg acgtgaagtc ggacaaggtc
     9841 gtcacggcga agaagcgctt cgaggccgcc tcggagcggc tgcgcaaggc cgcgaagtcc
     9901 cgcccggaga tcaaggtcct ggtcggctcg gcgagcgcgg agatcttcta cgtctccggc
     9961 tccgacctct ccgccgacct ggagtacttc aaggcgctcg gcgtgcacct cgtcgagccg
    10021 ccggagaacg ccaagaagga gagcgggggc tggttccaga acctgtcctg ggagaacgtc
    10081 gacacctaca aggccgacgt gatcatgatg gacaaccgca cgtcggcgtt gcagcccgcg
    10141 gacctggcca agcagaagcc cacctggggg aagctgcccg ccgtcaaggc cggtcaggtc
    10201 atcccgcgcg tcaccgagcc gatcttctcg tacgccaagt gcgcgccgat cctggaggac
    10261 ctggccaagg ccatcgagaa ggccaagaag gtctcctagc ggaggctggt gaacgctggc
    10321 cttggcgcgc cgtccatcgc ggccttcggc ctggctcgtc ctcaatcgcc ggacgggctt
    10381 gatctccccc agtgccgccc ggctgctctc cgcagccggg cggcactgcg tttgtgacct
    10441 gcgagcttgt ggacgacgcg tgaatatccc ggtgatgtgc gaggcggaag gggcccacga
    10501 gcactgtcac aatgaactta ggttaggcta acctaagttc catgtcgcgc cctcggccct
    10561 ccctgctgtg ccctgtcccg ggggcgcgac caagtcccct cacctggagg acagttcatg
    10621 cgctcgcacc tgctcaatga caccaccacg gagtcgtacc gcgcctccgt gaccgaagga
    10681 gtcgagcggg tggcggccag aatcgccacc acctcccgtc cgttcaccgg cgtctccgcg
    10741 gacgctctca ccccccgcgt cgcggccgtc gacctcgaca cccccctgca cgacaccggc
    10801 gccgccctcg acgagctgga cgagctgtac ctgcgcgacg ccgtctactt ccaccacccc
    10861 cgctacctcg cccacctcaa ctgcccggtc gtcatcccgg ccgtgctcgg cgaggccgtc
    10921 ctgtccgccg tgaactcgtc cctggacacc tgggaccagt ccgcgggcgg caccctcatc
    10981 gagcgccgcc tgatcgactg gaccaccgag cggatcggcc tcgggcccgc cgccgacggc
    11041 gtgttcacct ccggcggcac ccagtccaac ctgcaggcgc tgctgctcgc ccgcgaggag
    11101 gccaagacgg actcccccgc ccggctgcgc atcctcgcct ccgaggtcgg ccacttcagc
    11161 gtccagaagg ccgcgaagat gctcggcctc ggccaggacg ccgtcgtggt gatccccacc
    11221 gaccgcacca agcgcatgca gaccgtcgcg ctggcccgcg agctggcccg cctggacgcc
    11281 gagggcctcg tcccgatggc cgtcgtcgcg accgcgggca ccaccgactt cggctccatc
    11341 gacccgctgc cgcagatcgc cgacctctgc gcgcagtacg agacctggct gcacgtcgac
    11401 gccgcctacg gctgcggtct gctcgcctca cgcacccgcc gtgacctcct cgagggcatc
    11461 gagcgcgccg actccgtcac ggtcgactac cacaagtcgt tcttccagcc ggtgagttcg
    11521 tcggcgctcc tggtccggga cgcggcgacg ctgcggcacg ccacgtacca cgccgagtat
    11581 ctgaaccccc ggcgcgcggt gcaggagcgc atccccaacc aggtcgacaa gtccctgcag
    11641 accacccgcc gcttcgacgc gctgaaactg tggatgacgc tgcgcgtgat gggcgccgac
    11701 gccatcggcg acctcttcga cgaggtgtgc gccctggcgg acgagggctt cgacctgctc
    11761 gccgccgacc cgcgcttcga cgtcgtcgta cagccgcagc tctccacgct cgtcttccgc
    11821 tacatcccgg cggcgatctg cgacccgacg gccatcgacc gcgccaacct gtacgcccgc
    11881 aaggccctgt tcgcctccgg tgccgccgtg gtcgcgggca ccaaggtggg cgagcgccag
    11941 tacctgaagt tcaccctgct caaccccgag accacggccg ccgacatcgc cgccgtcctc
    12001 gacctgatag ccggccacgc cgagcagtac ctgggagaga accttgaccg cgccagctga
    12061 cctccgcgac gcgcggccga cagcctcgaa gacgccgacg gcggcccggc cgacgtacga
    12121 cttcatcggc atcggcctcg gccccttcaa cctcggccta gcctgcctca ccgagcccct
    12181 ggacgatctg aacggcctgt tcctggagtc caagccggac ttcgagtggc actccggcat
    12241 gttcctggac ggcgcccacc tgcagacgcc gttcatgtcg gacctggtga cgctcgccga
    12301 tccgacctcc ccgtactcct tcctgaactt cctgaaggaa tcggggcggc tgtactcctt
    12361 ctacatccgc gagaacttct atccgctgcg ccgggagtac aacgactact gccgctgggc
    12421 cgccgggaaa ctctcgtccg tccgcttcgg cacgacggtg acacgggtga cgtacgacaa
    12481 cggcctgtac ttcatcacca ccggctccgg cgacaccttc cgcgcccgcc acctcgtcct
    12541 cggcaccggc accccgccgc acatcccgga ggcgtgccgg ggcctcggcg gcgacttcct
    12601 gcacaactcc cgctacctgg agcacaagga ggagctgcag aagaagaact cgctgaccat
    12661 cgtgggcagc ggccagagcg ccgccgagat ctactacgac ctgctcgccg acatggacac
    12721 ccacggctac cgcctcaact gggtgacccg ctcgccgcgc ttcttcccgc tggagtacac
    12781 gaaactgacc ctggagatga cctctccgga gtacatcgac tacttccacg cactgcccga
    12841 ggacacccgc taccgcctgg agagcgagca gaggagtctc ttcaagggca tcgacggcga
    12901 gctgatcgac gccatcttcg atctgctgta ccagaagaac ctggacgggc ccgtgccgac
    12961 gcggctggtc accaacgcga gcctgcggaa agcccgttac acccatggcg tctacaccct
    13021 cggcctgcgt caggaggagc agggcaagga cttcgaggtg acgacggagg gtctgatcct
    13081 cgccaccggc taccggtacg ccgtccccgc gttcctggag ccgctgcgcg cgcacctgcg
    13141 cttcgacggg cacggccgtt tcgacgtggc ccgcaactac tccgtcgacg acagcgggcg
    13201 cggcgtcttc ctccagaacg ccgccgtcca cacccactcc atgaccagcc ccgacctggg
    13261 catgggcccg taccgcaacg cgtacatcat ccgcgagctg ctcggccgcg aggtctaccc
    13321 ggtcgagaag tccatcgcct tccaggagtt cgccgtatga gctggatgag agggacgggc
    13381 cggacgagcg gcgtgagcgg gatgaggcgc acgccgagca gggaccgcgg cgtcggcacc
    13441 ctcgccatgc gccccctcga cccgttcgaa gacaccgagc tggtccactc ctgggtcacc
    13501 caccccaagt cggccttctg gctgctccag gacgcccggc tgcaggacat cgagcgcgag
    13561 tacatggcca tcgccgcctc cgagcaccac gacgcgttcg tgggcctgca cgacggggag
    13621 cccgcgttcc tgatggagcg ctacgacccc cggtacatcg agctggtcgg cctgtacgag
    13681 cccgagcccg gcgacgtcgg catgcacttc ctggtcgccc ccaccgaccg gccggtgcac
    13741 ggcttcaccc gcgccgtcat cgccacggtg atggagcacc tgttcgccga cccgcgcacc
    13801 catcgcgtcg tcgtcgagcc cgacgtcacc aacacggccg tgcaccgcct caacgaggag
    13861 gtcggcttcg tgccggagcg cgagatcgac aagccggaga agcgggcact gctcagcttc
    13921 tgcacccgcg agagttacga cgcggccgtg gtgcgccacg ccgtggcgac acgccccacc
    13981 gcagtttctg gagcacggac atgaccctga cccccgccgc acccctgtcc cccgccgccc
    14041 cccggacgcc gctgtcggcc ctgtccccgc aggcccgggc cgtggaccat ctgaacccgg
    14101 agcgctgggc cgaggccaac cggctcctca tccgcaaagc cctcgccgag ttcgcgcacg
    14161 agcgcctcct cacgccggag gacctgggcg cgggccggta cgtcgtccgc agcgacgacg
    14221 gtctgacccg ctaccgcttc gccgcgcgcg tcttcgccct cgaccactgg gccgtcgacg
    14281 ccgcgtccct cacccggcac cgcgacggcg tcgaactccc cctgaacgca ctggagttct
    14341 tcaccgagct gcgcggcacc ctcggcctga gcgagaaggt cctgccggtg tacctggagg
    14401 agatctcctc caccctctcc ggcacctgct tcaaactcgc caagccccac gtctccgccg
    14461 ccgacctggt caccgccggt ttccaggaga tcgagaccgg catgaccgag ggccacccct
    14521 gcttcgtcgc gaacaacggc cggctcggct tcggcgtgca cgagtacctg tcgtacgccc
    14581 ccgagaccgc gagccccgtc cggctcatct ggctggccgc gcgccgcgac cgggccgcgt
    14641 tcaccgcggg cgagggcctg gagtacgagt cgttcctccg cgccgagctg ggcagggaga
    14701 ccctggaccg gttcgacgcc gtgctgcgcg cccaggacct cgacccggcc gactacctcc
    14761 tcatccccgc ccacccctgg cagtggtgga acaagctgtc cgtgaccttc gccgccgaga
    14821 tcgccgaccg gcgcctggtg tgcctgggcg agggcgacga cgagtatctg gcccagcagt
    14881 cgatccggac gttcttcaac gcctccgccc cggccaagca ctatgtgaag acggcccttt
    14941 ccgtcatcaa catgggcttc atgcgcggcc tctcggcggc gtacatgaag gcgaccccgg
    15001 ccatcaacga ctggctccac ggcctcgtcg cctccgacga ggtcctgcgc tccaccggcc
    15061 tcggcatcat ccgcgagcgc gccgccgtcg gctaccggca cctggagtac gaagccgcca
    15121 ccgaccgcta ctcgccgtac cgcaaaatgc tcgccgcgct gtggcgggaa agccccgtgc
    15181 ctgccctcaa ggacggcgag agcctcgcca ccatggcgtc gctgctgcac accgaccgcg
    15241 acggggcctc cttcgcgggc gccctcatgc aacgctcggg cctggccccg gcggagtggc
    15301 tgcgccgcta tctgcgcgcc tatctgacgc cgctccttca ctgcttctac gcgtacgacc
    15361 tggtgttcat gccgcacggc gagaacgtga tcatggtcct gaaggacggt gtcgtcgacc
    15421 gggtcctgtt caaggacatc gccgaggaga tcgcggtgat ggacccggcg gcggtgctgc
    15481 cgcccgaggt cgagcggatc cgcgtcgacg tgcccgagga ccgcaaactc ctgtcgatcc
    15541 tcacggacgt cttcgactgc ttcttccgct tcctgtccgc gagcctcgtc accgagggcc
    15601 tcctcgacga ggacgtcttc tggcgcacgg tcgccgagtg cgtccgcgac taccagcact
    15661 ccatgcccga actggccgac aggttccggc agtacgacat gttcgcgccc gagttcgcgc
    15721 tgtcctgcct gaaccggctc cagctgcgcg acaacgagca gatgctggac ctcgccgacc
    15781 cggcgggcgc cctccagctc atcggcaccc tgaagaaccc gatcgcctag accgggctgc
    15841 ccgagaccgg gcggggctcc gcggacggtc ccgcggagcc ccgctcacga atgcccctgc
    15901 cgtccctagc gcttgccggg ccagggcacc tgcggcgact tgtagtaggt gatgccgagc
    15961 gcgtcccagc gcggcgcctg ctccgcgagc cgcgtcctgt acgtgttcca gtcgtgcgtg
    16021 gacgcgggcg accagccgag ctcggcgatg ccgggcaggc gcgggaacgc catgtagtcc
    16081 agctgcgcgg gcgtggacag ggtctccgtc cacagcggcg cctcgacgcc gagcaccgcg
    16141 tcggccgggg ccccttgcag atacgtgccc gggtcccagt cgtaggagcg ctgcacctcg
    16201 acgtagcccg cccaggacag gccgagcggg gtgtccttgt cgtacttcat gtcgaggtag
    16261 gcgcggtcgg ccggggagag caccagcttg gtgcccttct tcgccgcgtt cacgacctgg
    16321 tcgcgctcgg cctggccggt gcggtcgtag ccccagtact gggcgacggc gccctggacc
    16381 gggttggccc cggccagttg gtgccagccc atcacgttct tgccgtactt ggtgacgagg
    16441 ggctgcacct tgcccatgaa cgtcacgaag tcctcgtggc tggtggagtg cgcctcgtcg
    16501 ccgccgatgt gcacgctccc gccgggcgtg agcgcgctca gctcccggac gacgtccgcc
    16561 acgaacttgt acgtcacgtc cttcttgacg cacagcgagc tgaagccgac gttcgtgccg
    16621 gtgtacagcg gtggcgcgac gccgtcgcag ttcagttcgg cgtacgaggc gagcgcggcg
    16681 ttggtgtggc ccggcatgtc gatctccggg acgacctcca tctgccggga cgcggcgtag
    16741 gcgacgatct ccttgtactg ggccttggtg tagtggccgc cggggccacc gccgacctgg
    16801 gtggaaccgc cgtacgtggc caggcgcggc caggagtcga tggcgatgcg ccacccctgg
    16861 tcgtcgctca ggtgcagatg cagcttgttc atcttgtaca gcaccatctg gtcgatgtag
    16921 cgcttgacgt gctcgaccgg gaagaagtgc cgggacacgt ccagcatcga accgcggtag
    16981 gcgtagcgcg gcttgtcctt gatggtgccg cccgcgatca gccacggtcc cggctgcttg
    17041 gtcttccgct ccgcggcggc gggcagctgc tggcgcaccg tctgcacgcc gtagaagaga
    17101 ccggcggacg accgggacgt gatggtgagg gagccgcgct tggagatgac gcggtagccc
    17161 tcgtcgccga gggccctgtt cgccggctcg gcactgatgc gcagccggat ggcgtcgccg
    17221 cccccgcggt cggtgaccgg gaggcggtag ccggtggagg ggcgcaggac gcccgcgagg
    17281 tactcgccga cgcggcgctc ctcgggccgg tcgccgacgc gtatgcgggt cttggaggtg
    17341 atctcgaacg cggatccgcc cggctccgcc tgcaggggca ccggcacgac gcggccgagc
    17401 ggaacgggct cggcccggtc gggagcgggg ccgggggcgg ccgccgagga cgatgtcccg
    17461 gcagcggcga tcagcaggag tgatccgatg acacaggcag ttctgtggtg ctgtctcaca
    17521 agcgggtccc ttcgccgggc aacgcggatg tgacgcagtc gaaccgttca ccatgcgtac
    17581 cgcgcacccc agaccaggtc aaggtgtaga ccacctggcc cagcacacga tgcgagaatc
    17641 agttcatggc ggaaatcatc cagcgcgacg gcacctggac cttcgacgga gagacgctgc
    17701 ggctcgtccc cggccgcgac aaagccgtct cgttgctgcg caagaccctc ggcgaactca
    17761 cggtgccgct cacggcgttg gcgggcatcg ccttcgaaca ggggaagaag agcggccggc
    17821 tgcgactgcg cctgcgggac ggcgcggacc cgctgctcca ggcgacgggc ggcaaactca
    17881 ccgacgcctc cgacccgtac caactcaccg tggagccgga ccggtacggc gtcgcggagt
    17941 acgtggtcga cgaggtgcgc aacgcgctgc tcctggagca ggtccccgcc aagcgctgcg
    18001 agagctatct gttgtcgggc ccctcggtgc cgctgcaggt cgccgccggt gacgccacgg
    18061 tgagcttcga cggggagcac gtccgcctgg agtggaactg gaagacggag gaggccaagg
    18121 ccgcgtccgg cacccgctcc atcgacctcg ccgatgtcgc cgccgtggag tggcagcccg
    18181 ccataggcct ggagaacggg tatctgcggt tcacggtgaa gaacgccccc accaaggccc
    18241 cgccgaagta cgacccgaac tccgtggagc tgtggggctt caagaaggac ccgctgatgg
    18301 cgctcgtcgc ggcggccgtg caggcccgcc tgccgcaccc ggccacgccc gcgaaggcgg
    18361 cgctcgccga ggacgcgccg gccgcctccg acgccccggc cgcgctgccc gccgccccgg
    18421 ccgaggacag ccatgacgcg ctgctccggc ggctgcggga gctgggtgag ctgcaccaga
    18481 gcggcatcct cacggacgag gagttcgcgg cggccaagca ggcggtgctg aagcggatgt
    18541 gaaggggttc ggggcccgat aaaagtacgg accaagccgc tcctgcccga tatcgggcag
    18601 gattcttgcg aaagctcccc tcgtacccca ggatcaacgg gtgcacgaag aacttgtcga
    18661 tcacctgacg cgctccaccc agctccatcg cggcgaggcg ctgcgggtga tccaggacgt
    18721 gctcgcgtac ttcgacgaga cgaccgaggc gttcgtccgc cgccgccacc gtgagctcca
    18781 gggtcagggc ctggtgaaca cggagatctt cgagcggatc gcggcggacc tgcgctatcg
    18841 cgcggtcgcg ccgcccgagc tcacgctcag acagctgcgc cgcgtcgtct acggctgacc
    18901 cctgtccaca ccaacccgag ggacccttat gtgcggaatc gtcggatata tcggcaagcg
    18961 tgatgtcgcc ccgctgctcc tggaaggcct gcagcgcctg gagtaccgcg gctacgactc
    19021 cgcgggcgtc gtgatcacca gcccgaaggc caccggcctg aagatggtca aggccaaggg
    19081 ccgcgtccgc gacctggagg cccgcgtccc caagcgcttc accggtacca ccggcatcgc
    19141 ccacacccgc tgggccaccc acggcgcccc ctccgacgag aacgcccacc cccacctgga
    19201 cggcgagaac aaggtcgccg tcgtccacaa cggcatcatc gacaacgcct ccgagctgcg
    19261 cgccaagctg accgcggacg gcgtcgagtt ccgctccgag accgacaccg aggtgatcac
    19321 ccacctcatc gcccgctcca cggccgagaa gctggaggac cgggtccgcg aggcgcttcg
    19381 ccacatcgag ggcacgtacg gcatcgccgt cctgcacgcc gacttcaacg accgcatcgt
    19441 cgtcgcccgc aacggctcgc ccgtcgtcct cggcatcggc gagaaggaga tgttcgtcgc
    19501 ctcggacgtc gccgccctgg tctcgcacac ccgccaggtc gtcaccctcg acgacggcga
    19561 gatggccacc atcaaggccg acgactaccg cacgtacacg accgagggtt cgcgcacctc
    19621 ggccgagccg accaccgtgg agtgggaggc cgagtcgtac gacatgggcg gccacgacac
    19681 gtacatgcac aaggagatct tcgagcagcc cgacgcggtg gaccgcgtcc tgcgcggccg
    19741 catcgacgac cgcttcgcca ccgtgcacct cggcggcctg aacctggacg cgcacgacgc
    19801 ccgcaaggtg cgccgcgtca agatcctcgg ctgcggcacc tcgtaccacg cgggcatgat
    19861 cggcgcccag atgatcgagg agctggcccg catccccgcc gacgccgagc ccgcctcgga
    19921 gttccgctac cgcaacgcgg tcgtcgaccc cgacaccctg tacgtcgccg tctcccagtc
    19981 cggcgagacc tacgacgtgc tcgccgccgt gcaggagctc aagcgcaagg gcgcccgcgt
    20041 cttcggcgtc gtgaacgtcg tcggctccgc gatcgcccgc gaggcggacg cgggcgtgta
    20101 cgtgcacgcg ggcccggagg tctgcgtcgt ctccaccaag tgcttcacca acaccaccgt
    20161 cgccttcgcg ctgctcgccc tgcacctggg ccgcatccgt gacctgtcgg cctccgacgg
    20221 caagcggatc atcgcgggcc tgcgccaact gcccgcgcag atcgagcaga tgctggcgcg
    20281 cgaggacgag atcaagaagc tcgcggagga gtacgccgac gccaggtcga tgctgttcat
    20341 cggccgggtg cgcggttacc ccgtggcgcg cgaggcctcc ctgaagctca aggagatctc
    20401 ctacatccac gccgaggcct accccgcgtc ggagttgaag cacggcccgc tcgccctgat
    20461 cgagcccgcc ctgccgacgg tcgcgatcgt ccccgacgac gacctcctgg agaagaaccg
    20521 cgccgccctg gaggagatca aggcccgcag cggcaagatc ctcgcggtcg cccaccagga
    20581 gcaggagaag gccgaccaca cgatcgtcgt cccgaagaac gaggacgagc tcgacccgat
    20641 cctgatgggc atcccgctcc agctcctcgc ctaccacacg gccctggtcc tgggccggga
    20701 catcgacaag ccgaggaatc tcgcgaagtc ggtcacggtg gagtagtcct gccactgatc
    20761 acggcggcga aaattgagca acccccacgg tgagcaacca cctccgcgag agcggcggcg
    20821 gtttagccgc aaaggggcga acggtcccct gtgtgtgcca ccaaacgcac aggggaccgt
    20881 tcttcgaggg accggggtcg cccattaccc cggcccgcgc ctgctcagcc ggcggccgtc
    20941 accccccgac ctgcagggca tacaccgcgc acgtcggcgc ggaacgccgg acgccgccgt
    21001 acgggcactg ggccgtggtt gccccaacaa gcggtatgta cccttcacaa gggcacgaac
    21061 cacctctacg cgcgagtaga tttatgcgtc gccagcaggc ggccgacgcc gcgcactcct
    21121 catcccacct gggacgaaag ggagttgcgg agctacggga tcacgacgac gggccgttgc
    21181 gcacggcgcg cgagacggcc cgcgaccgag ccgaagatgc gccccacgat cccgtgcgtc
    21241 gagccgacca cgatggcgtc cgcggagtac tcccggccga cctcttcgag ttcgtggcag
    21301 atgtcgccgc cgcgctcgac caggatccag ggcacctccg acagatactc cgcgcaagcc
    21361 agttcgaggc cgaggacctc ggtgcggtgg tcggggacgt cgacgaagac cgggggttcg
    21421 cagcccgccc agacggtggt gggcagccgg ttggcgacgt ggacgatgat caggccggag
    21481 ccggatcggt gtgccatccc gatcgcgtag gcgagggccc gctcgctgga tgtcgagccg
    21541 tcgaagccga cgacgacacc gtgccggaag gcgggatcgc aggagtgacg tggttcttcc
    21601 gccgcttggg gggtcgcgct cggatcggcg acctgccgct tgcggttcgc gggttcggag
    21661 aattcgtgac cggccatcgg tgtctcggcg aaggagtcct ctgtgggagg gtcggctttt
    21721 tccaggtgcg cggtctggct gcgcggtagg gaacatggcg gtacaagcag gttcggatgt
    21781 gtgcggatca ccgcaggtcg ggcactgtgg cgaagcacat caccggacgc gtgtccggga
    21841 atcatcttcc caacccctta cccccaaggg tacggccgca ctcctctcct gcccagctct
    21901 cgacgagcct cgtccgggtc cccgcggaac ccgcccggga ggtgccccgg ggcgccgccg
    21961 caggcctgtt cgaggcccgc aaaaggcccc actgaggcct cacggcgttc accggagcat
    22021 gcatgagccg ggcccggatg gcaatggcgg ctgccccgta caggcggttt gcgcccggtt
    22081 cgcgcgcgcg gccccttcag gccagtgacc ggccggtcgg ccgcgcgttg aacccttgaa
    22141 accactcttt cggagacatc cgccgccacc gccacaccgt gcgaaaccac tgccgcaggg
    22201 agcacgccgt gccaggaccg tccaccgccg ccccggtcgt cgcagccacc acccgccgcc
    22261 gcgcgcccga gggggcgcgc gagcgccggg ccccctcggt cccgacgccc cgccccgccc
    22321 ggaccccggc ccccgccccg caggaagcgg cgagcgacgt ggtgcgctgg gcggcgttct
    22381 cctgcgtcct ggttccggtg gtcctcgtcg ggtacgggac ctcgctggcc ggcgcgggcg
    22441 gagcggccct cggactcgcc gccgtgaccg gggtgtgccg agtgctcctg cagcagtccg
    22501 agcgcggggc cgcgcgggcg cgcgcgcagc ggggtgcggg cacgcgcgga cggcggcagc
    22561 ggcaggcgcc cggggcgcac cggggcggcc gtcgtccggg gccggatgcg ccggtggact
    22621 gactgattcc cacgcactcc cccgtatgtt ttcagccaac ttcccagccg tcgacattcc
    22681 caggcggaac agggggtcaa cgcacgtctc accaggggcg aaaggagcgg ggaaaggctc
    22741 tgcaccctac gttgaccggc cactggcaca aggcgcactt ccctgcgcgg cccgtgagtg
    22801 cgacgcttcg tgatcgaatg cttcacgcca agttgccatg tcgacaatgc gccgggtgct
    22861 gaactggtca cagcggcgtc acacgacgca gtagattcga tcttgactgt agtacggcgg
    22921 gggactggtg gaggaccgag gggaaacgtg caggagcgac aggcccaaaa agcacgtcaa
    22981 gaacagggag ccgcgacgac cgaggggggc ttagcaccat gagccacgac tccactgccg
    23041 tgcaggaagc cgcggcgcgg aaactctccg ggcggcgacg tcgggagatc gtcgcggtgc
    23101 tgctcttcag cggtggtccc attttcgaga gttccatacc tctctccgtg ttcggcattg
    23161 accggcagga cgcgggagta ccccgatacc ggctgctcgt atgcgccggt gaagaggggc
    23221 cgctgcgcac caccggcggg ctcgaactga ccgcgcccca cgggctggag gcgatctcgc
    23281 gggcgggcac cgtagtggtg ccggcctggc gctcgatcac atcgccgccc ccgttggagg
    23341 cactcgacgc gctgcgccgc gcgcacgagg agggcgcacg catcgtcggg ctctgcaccg
    23401 gcgcgttcgt cctggccgcg gccggtttac tggacggccg accggcgacg acgcactgga
    23461 tgtacgcgcc gacgctggcc aagcgctacc cgtccgtgca cgtcgacccg cgcgagctgt
    23521 tcgtcgacga cggcgatgtg ctcacgtcgg ccggcaccgc ggccggaatt gatctctgcc
    23581 tgcacatcgt gcgcacggat cacggcaatg aggcggcggg cgcactcgcc cgcaggctcg
    23641 tcgtgccacc gcgccgggcc ggcggccagg aacgctacct ggaccggtcg ctgccggagg
    23701 agatcggcgc cgacccgctc gccgaggtcg tcgcctgggc gctggaacac ctccacgagc
    23761 agttcgacgt ggagacgctg gccgcccgcg cctacatgag ccggcgcacc ttcgaccggc
    23821 ggttccgctc gctcaccggg agcgctcccc tgcagtggct gatcacccag cgggtgctgc
    23881 aggcacagcg gctcctggag acctccgact actccgtcga cgaggtcgcc gggcgctgcg
    23941 ggttccgctc gccggtcgcg ctgcgcggcc acttccggcg tcagctcggc tcctcgcccg
    24001 cggcctaccg cgcggcgtac cgggcgcggc ggccgcagaa cgagcgatcc ctggagtccg
    24061 cgtcggcacc gtcggcggcc ccggccgcct ccggggccac cgcggcggcc gccatggcca
    24121 ccggaccctc ggtggtcgcc acggacgggc caggacctgg tccgggcgga aatcccggtc
    24181 tgacaccggg ccccgtcccg tcccagaccc ggcgtacggc cgccgccagc tcactcggcg
    24241 ccgcggcttc gctgccgatg gatccgggca agccgcactc cgacgcgtac gcgccgggcc
    24301 gcactcccct gcccggtcag aggagcgcgc cgtagggttg ggcgcatgaa cgatcgcatg
    24361 gtgtggatcg actgcgagat gaccgggctc tcgctgacgg acgacgcact tatcgaggtg
    24421 gccgcactgg tcaccgactc ggaactgaac gtgctcggcg aaggtgtgga catcgtgatc
    24481 cgcccgccgg acgcggccct ggagaccatg cccgaggtgg tgcggcagat gcacaccacc
    24541 tcggggctcc tcgacgagct ggccggcggc accacgctgg ccgacgccga ggagcaggtc
    24601 atcgcctaca tccggcagca cgtgaaggag ccccgcaagg ccccgctgtg cggcaactcg
    24661 gtcggcacgg accgcggctt cctgctgcgg gacatgccga ccctcgagga cttcctgcac
    24721 taccgcatcg tcgacgtctc ctccatcaag gagctggccc ggcgctggta cccgcgggcg
    24781 tacttcaaca gcccggacaa gaacggcaac caccgcgccc tcgccgacat ccgcgagtcc
    24841 atcgcggagc tgcgctacta ccgcgaggcg atcttcgtcc cgcagcccgg gcccgactcc
    24901 gacaccgcca agtcgatcgc cgcgaagcac gtcctgcctg cggattaacc ctccgcggca
    24961 ccccgtgtac ggggtccgta aaaggggtgc gcgagcaccc cttcggaccc tgtacacttt
    25021 ttctcggccg gtcagaagaa caccaaagac cggctcatgg tgggtgtagc tcagttggta
    25081 gagcacctgg ttgtggtcca ggtggccgcg ggttcaagtc ccgtcactca ccctgaagga
    25141 tcggcccctg acccgggaac gggttggggg ccgatttgtt tccctggcag gggcggcccg
    25201 tctgcacggg gcagggctca ggaagcatga cgcgtcacat cagtgatccg gcagacgacc
    25261 ttccccgaag cctcccggaa gccggacgcg gactcgttcg cgacctggtc cggcgccaag
    25321 ttgctcgtac cagcaactcc ctcggcgatg cgcacgccgt cggcgtccac gaactccacc
    25381 tcgacccagt agtcggacgt cttcgagctg tggttggtga tgcgcaactc agcgttgggc
    25441 cagcgggtat tcggctccac cgaacacttg atgatctcca catcggcgcg cggacccgac
    25501 acgggcggag cggtctgctc ctgcgagggg ctcctgccgg gcggcgtctc ctcgtcgctg
    25561 ccgccgatga gcgccaccgc caccaagatc gccatcaggg cgacggccat caggaccacg
    25621 tacagaagca cccgcccgag ccgcctcctc ttgggcggag ggcgctgccc ccacccactc
    25681 ggcggtgctg cggcaggagg ccgctgaggt gacatggcgc cctcaggtgg ggcgtggggc
    25741 taatacgtca agcatctctc cgcacggcga aaagcgcacg tcaggccttg tctccggggc
    25801 cgcgcgcaca gcgccgagcg cctcaggacg acgccctgca caccagttcc gtaggcagca
    25861 cgatctgctg gcgggcgagg tggcgggtcc cggcggggcg ggtgtcggct atttcggcga
    25921 ggaggacgtc agtcatggtg cggcccatct cggtgatggg ctggcgcacg ctggtcagcg
    25981 gtgggtccat atggcgggcg atggccgagt cgtcgaagcc gaccagggcc acgtcgtccg
    26041 gtatccggcg gccgacctcg cgcaggacct ggcgggcgcc cgcggccatc acgtccgagc
    26101 cggcgaagac cgcgtccagg tcggggcggc gggccaggag ctcggtcatg gcgcggcggc
    26161 cgccgtcctc ggtgaagtca ccgcgggcta tcagggactc ctcgacgggg tggcccgcct
    26221 cggtgagggc gtcgcggtag ccgtcgaggc ggcgctgggc gccgtacacg tccaggcgcc
    26281 ccgtgatcgt ggctatcgtg cggcggcccc ggtcgaggag gtgaccgacg gccgcgcggg
    26341 cgcccgcgaa gttgtcggag tcgacggagg ccagcggctc gtcggccgag cggcggccgc
    26401 tgatcacggc ggggatgccg agctgccgga gcaggtcggg aagggggtcg tcggcgtgga
    26461 cggagacgag caggacgccg tccacgcggt gcgccgacag gtactgggcg aggctgcggc
    26521 gctcccggtc accgcccgcg aacgtcagca ggagctgcat gtccgtctcg gcgagcgccg
    26581 cgcccacccc gtggatgatg tccgagaagt acggctcggc gaagaaccgc gactccggct
    26641 cgggcacgac cacggcgatc gagtccgtac ggttcgcggc gagcgcgcgg gccgccgtgt
    26701 tcgggacata gccgagctcc gcgaccgcct cctcgacggc ggcccgcgtg tgctcgctca
    26761 cccggggcga accgttgatc acccgggaca cggtgccgcg cccgaccccc gcccgcgcgg
    26821 cgacctgctc cagcgtgggc cgtgccccgc cgcgccccct gggctgaccg ctccccatca
    26881 gtgcctcccc acgacgcgaa tctaacagcc acgccacgac caccagcgac ggcgcccgcg
    26941 gcccgcaact cccggcgtcc ggtgccttga cacccccctg gcgagccgcg acccttcaag
    27001 gcatcacaca tgggagcgct cccaccctac ccggctctta cacgacccgc acgtcccgtc
    27061 cgagccaatt cctaccaact cgcccatttc atatgagagt tgaccggctt tcggtacgtc
    27121 cgggaccagg aggacgcaat gcgctacagg actcgaacgt cccgcacggc cgtggtcctc
    27181 gcggccgtca ccactcttgc cgccggactg ctcgccggct gcgcggagga ctccgacgag
    27241 gacgagcccg gtggctcctc gggcggcggc gggggcggaa agggcaagac gaccctgacc
    27301 gtcggggtgt tcggcgcctt cggcctgcag gaggccggtc tctacgacga gtacgagaag
    27361 ctcaaccccg acatcaacat caagcagaac tccgtacagc gcaacgagaa ctactggccc
    27421 gccctcctca cccacctgag cagcggcagc ggcctctccg acgtccaggc cgtcgaggtc
    27481 ggcaacatcg ccgagctgac cggcacccac gcgtccaagc tggtggatct cggcaagacc
    27541 tccggcgtcg acaagaacgc ctacctcgac tggaagtggc agcagggcac caccgacgac
    27601 ggcaagacga tcggtctcgg caccgacatc gggccgaccg gcatctgtta ccgcaaggac
    27661 ctgttcaaga aggccggtct gcccacggac cgggaggcgg tcggcaagct ctgggcgggc
    27721 gactggagca agtacctgga cgcgggcaag cggtaccaga agaaggcgcc caagggcacc
    27781 gccttcgtcg acggcgccac cggcgtgatg gcggccgtgc acgcctccgg caaggagaag
    27841 ttctacgacg ccgagggcga gctgatctac caggacagcg cgggcgtgca ggagggctgg
    27901 gacctcgcgg cgcagttcgc cgaggccgga ctcaccgcca agctccagca gttccagccc
    27961 agttgggacc aggccttctc caacggctcc ttcgccaccg tgacctgccc gccctggatg
    28021 ctcggctaca tcaaggacaa ggcgggcgac aagggcgagg accagtggga cgtcgccgcc
    28081 gcgccgaagc ccggcaactg gggcggctcc ttcctgaccg tgcccgaggc gggcaagaac
    28141 aaggaggagg ccgccaagct cgtcgcctgg ctgaccgccc cgaagcagca ggccaagctg
    28201 ttcgacaagc gggccagctt cccgagcgcc gaggccgcgt acgggctgcc cgaggtgaag
    28261 gacgccaaga acccctactt cggcgacgcg cccgtcggac aggtcttcgc caaggccgcc
    28321 gagggcgtgc cggtccagcc catcggcccc aaggacggga tcatctccca gtacctggcc
    28381 gacaccggga tgctcggcgt cgaccagaag ggcacgtctc ccgacaaggc ctgggacaag
    28441 gcagtgaaga cgatcgacaa cgcactggac cagtgatcat ccggtgaccg acatcccgag
    28501 cgacacccgt accgccgcgc cctccacggg ggaggagggc gcggccccgc gcgcgcgggc
    28561 cgtggcagcg ctcgacccgg ccgccgagcg ccgccgggcc cggcgcagcc gccgctaccg
    28621 ctgggacatg aagtggagtc cctacgccct gatcgcgccg ttcttcctct tcttcatcgc
    28681 cttcggcctc ttcccgctgc tgtacacggg gtgggcctcg ctgcaccgcg tggagctggg
    28741 gacgcccacg gacatggagt gggtggggct gcgcaacttc tcgcggctgc tggaggacga
    28801 cttcttctgg aacgcgctgc gcaacacctt caccatcggc atcatctcga cggtgccgca
    28861 gctggtgatg gcgctcggca tcgcccacct ccttcactac cgcctgcgcg gctccatgtt
    28921 cttccgcgtc gcgatcctca ccccctacgc cacctccgtg gccgcggcga ccctcgtctt
    28981 cgtgctcatg ttcagccgta ccgaccacgg catgatcaac tgggcgctcg ggctcatcgg
    29041 cgtcgatgcc gtggactggc agaacggcga ctggaccgcg cagttcgccg tgtcctcgat
    29101 cgtcatctgg cggtggaccg gctacaacgc gctgatctat ctcgccgcga tgcaggccat
    29161 ccccaacgat ctgtacgagt cggcggcgct ggacggcgcg agccgctggc agcagttccg
    29221 gcacgtcacg attccctcgc tgcggccgac gatcctgttc acctgtgtgg tgtcgacgat
    29281 cggggcgacc cagctcttcg gtgagccgct cctgttcagc cagggcgcga gccccaccgg
    29341 cggctccgac caccagttcc agacgctcgg tctctatctg tacgaacagg gctggttcaa
    29401 ccagcacctg ggccggtcct cggcgatcgc ctggaccatg ttcctgattc tcgtcctgat
    29461 cggcctggtc aactgggcga tcagccgctg gatccgcaga agcgcgtgag gggatgacgt
    29521 ggcaagcctc aagaaacgcg gcgccgggcg ccaactgcac ggcggcaagg tggcctacgc
    29581 cgtactgatc ctgttcacca tcggctccct cttccccctg gtgtggaccg cgatcgccgc
    29641 gtcccgcaac aacacgcggc tcgccgagac gcctccgccc ttctggttcg gcgggaacct
    29701 gttcaagaac ctggagatcg cctggaccga cgccaacatg ggcacggccc tgatcaacac
    29761 cctggtggtg gcgggcacca tcaccgtggg caccgtgctc ttctccaccc tcgcgggttt
    29821 cgccttcgcc
//
