LOCUS       NZ_BMVQ01000014        20290 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces anthocyanicus strain JCM 4739 sequence14, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVQ01000014
VERSION     NZ_BMVQ01000014.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces anthocyanicus
  ORGANISM  Streptomyces anthocyanicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces violaceoruber group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 172123)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:14:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,934
            CDSs (total)                      :: 7,858
            Genes (coding)                    :: 7,681
            CDSs (with protein)               :: 7,681
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 177
            CDSs (without protein)            :: 177
            Pseudo Genes (ambiguous residues) :: 0 of 177
            Pseudo Genes (frameshifted)       :: 73 of 177
            Pseudo Genes (incomplete)         :: 130 of 177
            Pseudo Genes (internal stop)      :: 16 of 177
            Pseudo Genes (multiple problems)  :: 37 of 177
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:48:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 151833
            Orig. end                         :: 172123
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVQ01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20290
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..20290
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20290
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:16331](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16331)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(1172..5398)
                     /locus_tag="IE283_RS30940"
                     /old_locus_tag="GCM10010348_62520"
     CDS             complement(1172..5398)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE283_RS30940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010348_62520"
                     /product="ATP-binding protein"
                     /protein_id="WP_193486906.1"
                     /transl_table=11
                     /translation="MTWPLWSTSDQSGLARYVVSGAEQLLTPGLDRRGIGDGPGGPLAL
                     ARALYGQLALQGLYYDVEGYTPSDHVQRIRTPAEILGSPGRRGTCLDLALLYAGLLLDY
                     ELLPVVVAQGEHAVTLVCRDHGLREWAGYRPGYEEFHDGVVHDPSVVRALVQSHAFVPV
                     ECTGFARITGSPEGGSELHPGEDTLAPSRRTDDGLLDFDTAVDVARRRILAADRPMAFA
                     FDVAIMRHHGIEPWQPPPAAAPQDSAAGDRVVSAGRAVGELTARSRHLLEAELAFLAPG
                     PGHPATPANVLKLLEDSPGVLLTGPAGAGKTRTLLEVAALAERDDWRVLYVRPDSETAN
                     THVEQAILAEPAARTLLLVDYLEVCAGLDLSGLLERVPALQSAAGHFAVLATSRQSRVP
                     HLVARGAVDDLTEVELCLDSAYHAAIAERVFASVAPLALQRLGPARMAEICGHRPVIAL
                     LIAQDAERRIRAGKDATPGRGPSRLMRWLRASLVQDGVVPAPRTPGDDADWLSGGDDIS
                     HSVRACALAAAACPLPKERLETLVQPVLDEAPRAGRARALIDNLLVMGWFEQVGDRLDV
                     THDLVTDELLGAVVVPRTGLRVRDTELTGLLDRTVDQPDVLDHLAGNAARLYGELARTA
                     QREQFGRACREWITARAGRIGEVCASAPEGGHTLYTLLHAEPWQSPVGQAWDTVVEPWL
                     RTAVPDADRSRFLRYALTGLPAGEALPTITAALVWLAGNTTAVEPVLAGLLRRTDLDHA
                     QRATAARRAQSWAASDAVETADDVTVVLRGLLAHPTGTTDLDRRSVEITADWFAGHATA
                     LPAGFVVRPLLEAHLLTAEESGTVTDNAVRWLSVHGAHPRVRTVLPVLLSSPRLSAGQQ
                     TTVVAHSLAWLESHLRRLPTAEVFHPLFARLTPRNPQYERLLILLETWLAAHPDHPDAA
                     WFLTRLLLSPGVSREATARHLRTAADWFNTYGDTLAQVARVQVLLTMARCLNSVTGDGE
                     PAAAVLDCLVRQLVESPGKSGIGLRQELARGALRDAGLRDAFVARARHALADGRTGPGA
                     VALLNLLFETAVTPLSTDRVQEAALDWLAHRTELVHLDLLTKAVERPLLSDERREQAVA
                     VCLAWIERHPDNTGVVAPLAGLLDSAGLAPPQAELVHARAQEWVRTMADPRPGGRLSAM
                     VLRSPAFPAECRTQALDTLKETVERLGVDAGVVLHDFVTGWSHATGPVDVLWFVLDWIR
                     AHPATPTAQMLLRRLVSIRADPDFVHAAARHALERLRADPLDHDAPLLLRALIGGPWML
                     PADVDAAAVLVRQWAAARPHHAHTLPLLRSVLNSSRLGAPHIRWAAQEIIRGAHRAPAG
                     PDAQLLTMVANSTRVDSDTADEAADGALARLGRLPAPPTAVKTLHALLGATHAATPAWG
                     ASESRP"
     gene            complement(5395..6858)
                     /locus_tag="IE283_RS30945"
                     /old_locus_tag="GCM10010348_62530"
     CDS             complement(5395..6858)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014503.4"
                     /locus_tag="IE283_RS30945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_62530"
                     /product="hypothetical protein"
                     /protein_id="WP_193486908.1"
                     /transl_table=11
                     /translation="MRQRLRDVIIVLPGITGSVLSRAGTPVWDASYRLIGKSVLQRQKT
                     VRALALDEGPLTADALLPRACLVPGLVKIDGYSRLTQALAAHFDVRHAVATGTEALPPS
                     NLIEFPYDWRLDNRVTARRLATVAERALADWRSHANIPDAELVVVAHSMGGLVARYFLD
                     VLGGHRLTRALVTFGTPFGGSLDALGYLADGYRKATLDLTDVMRTFPSVHQLMPADPVI
                     HDATAALPGTGTPRRISEVGPITGVDPHLAADAAEFHREITTGAKAVARGGFRYTVLPV
                     VGTHQRTWQSAVYDGSGVSLSRDLPDGVHRYFGDGDRDGDGTVGISSAAPADPLDVFAD
                     VFQAEKHSNLHNNPHVLNTLLGRLTKMQARVRPKLRGPEPLVDTGQLALGVDVEDQYAG
                     DEPVVVKAEVFAPDRPEKVTAVAEHTESGARHAVDLVPAPDGERTEETWRAELPPLAPG
                     AYRLEVVARGATALPPPVHDLFEVSEDGA"
     gene            complement(7013..7141)
                     /locus_tag="IE283_RS40260"
                     /old_locus_tag="GCM10010348_62540"
     CDS             complement(7013..7141)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE283_RS40260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010348_62540"
                     /product="hypothetical protein"
                     /protein_id="WP_281401927.1"
                     /transl_table=11
                     /translation="MSAQWSRTEQGLRSWESLDEGPFTELMNDLGLPGAVELASAP"
     misc_feature    complement(7222..7233)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     repeat_region   7401..8220
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=159295..159323
                     /rpt_unit_seq="ggggccatccccgcgggtgcggggagcag"
     gene            <8443..8767
                     /locus_tag="IE283_RS40265"
                     /old_locus_tag="GCM10010348_62550"
                     /pseudo=""
     CDS             <8443..8767
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964279.1"
                     /locus_tag="IE283_RS40265"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="GCM10010348_62550"
                     /product="sugar O-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GLNTAFGENVFVNQGMHLHGQGRHPYRQRRHDRPEGQPHHRRPST
                     APGRAPRVPLLRSDRHQGRRLDRDGCRDHTRGDHRCRCSGHS"
     gene            complement(8751..9914)
                     /locus_tag="IE283_RS30955"
                     /old_locus_tag="GCM10010348_62560"
     CDS             complement(8751..9914)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992140.1"
                     /locus_tag="IE283_RS30955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_62560"
                     /product="hypothetical protein"
                     /protein_id="WP_246550795.1"
                     /transl_table=11
                     /translation="MDPYGPTAQRFPLVARFRPPCPPLPERVRGLVELADAAVEKSDQG
                     LASAACNQAALIASDVGLPALAGALCRRHAAAYLHACPLPGMSAIRGLEPIVNLARLRI
                     RAGDADEGRRRLLALHAAVEAGTAARFEGIAVPSDLTTTDDDRREVRAWLWRVLLADGT
                     RTLTAKGRWTEAEAHIEAHRGVGSRMLDGRQTAVVAALTAGNTARAAALLAGTTPGAPW
                     EQAVTACLTVLCRRAAGQPVDRQAADLATAYLGRKTETGMTVFDIRLGLTALDATGSTE
                     TPSARRIVDDLHRRSRKAQDGYAARETLASTLFTEMASGRQVQDCRDLVRACALGAGGM
                     PDELREDLASVARTGDSVIRTSLGRGLDLRSAARSGPGSTTGLSRSS"
     gene            complement(10001..12091)
                     /gene="fxlM"
                     /locus_tag="IE283_RS30960"
                     /old_locus_tag="GCM10010348_62570"
     CDS             complement(10001..12091)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543781.1"
                     /locus_tag="IE283_RS30960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_62570"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_193486910.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 7.6e-27, bitscore:
                     87.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 3.6e-48, bitscore: 156.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPDRWQQHNITFADRASAQRAVSERITPVLLAAEQDGQLTGWWF
                     MNKQPWPLRYRADEPSPAVEAVLSDLVQEGGPVVSWLPCVYEPETEAFGGTEAMEVAHE
                     LFHRDSRHLLTHRPGPESLGRRETTVLLASAMMRAAELDWFEQGDVWAKVAALRPSTGR
                     PPSERADELARAMRKLMTVDAHCLCRPSGPLAGNRGWVDAFERAGAELAALAGRGALTR
                     GLRAVIAHHTIFHSNRAGLLRDDQSALSDIAREVVMGTNDNATPPAEATPGTDSVHGAN
                     DTITTTDVPAVGAEHLRDALVDALRAQGHARTPAVENALRTVPRHVFVPGASLEDAYAD
                     APVHIKYDTDGTSISCASQPSVVALMLDQLDVRPGERVLEIGAGTGYNAALLARLTGES
                     GHVTTLDVDDDLVAGARAHLAAAGIGNVTAVTCDGALGHAEGAPYDRIVATVGAHGVPH
                     AWLRQLAPGGRLLVPQRLKGTVSRSIAYEQRDGRWVSLGSEMNTFMPLRRGVADDARRV
                     VPLSTDGTVRLQVPAGQNIDADALTGVLYQPRTEEWTGMTVRGMESPEWMELFVSCSLP
                     SGLIRMLFPKTAKGTLLTEDPYPSSSVVVDKGAVAYLARRVSERKTPEGGKLWEFGVIG
                     HGPGGDELAARVADAVRTWDREYRGREATFELLPLDAPTTEPSPGLFTLDTPLNRIVVD
                     WR"
     gene            complement(12118..13389)
                     /locus_tag="IE283_RS30965"
                     /old_locus_tag="GCM10010348_62580"
     CDS             complement(12118..13389)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489258.1"
                     /locus_tag="IE283_RS30965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_62580"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_193486912.1"
                     /sec_met_domain="LANC_like (E-value: 8.4e-43, bitscore:
                     139.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAQTAKSTLGLADAVAEHLADPGSVSLPTAHRQHLALGLPGIAL
                     LHIVRAAAGLGPWQRAHDWLAAASREPLTSGPDSHPFYGAPALAYAVACAVDYLPGAYR
                     RALATLDRQTAADVSCRLDAAHRRIDTGRHPALAEFDTVRGLTGYGAHLLRRAPDSSVL
                     RDVLDYCVRLTHPITHDGETLPGWWTPTGPSGRPDERFPGGHANSGMAHGIGGVLALLA
                     LAARHGIFVAGHEEAAGRILAWLDHWQEDTGGGPAWPYWVTRPELRADRLAPFARRRPS
                     WCYGTAGLARALQLASLALGDTRRRLHAENALVAALTDPAQLNATTDKALCHGFAGLAH
                     IAACAADDAHPSNAGRLRAAIPTLLAAVHPPGTDPAHTTTALIQHEAYGPGLLDGAAGI
                     ALAFLSSGAAVPPRTAWDACLLVA"
     gene            complement(13386..16331)
                     /locus_tag="IE283_RS30970"
                     /old_locus_tag="GCM10010348_62590"
     CDS             complement(13386..16331)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383506.1"
                     /locus_tag="IE283_RS30970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_62590"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_193486930.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.8e-203,
                     bitscore: 669.4, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 7.8e-19,
                     bitscore: 61.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.6e-25, bitscore:
                     81.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVLADDDLVEALEHASPVLAARVRSVCAAPEPPPRKARRAALS
                     VARYLLRARHRATPFGLFAGVTTAGFDPRPRVSWGEEHVVVGRAGAEWLAAVVEQLESC
                     PDFLRRLPLVVNNTVTSRGDRLVVPFQSDDRGERPRAVETSLALTEPVRTVLAVARGPV
                     WGGALVDKLEAEFPEAGPEKARRLLAELVRRRVLVTGLQAPSTETDALGHLLDRLRTAD
                     AESLPALAGTVRELGEIHAALGQCASRGGRDSVAARMRALVPGLRRHPVALDLRLDAQL
                     ALPDAVARETERAALILTRVSARPYGTAAWGAYHQRFYERYGIGTMVPLLEVVGDSGIG
                     YPEGYPGSSPSPRRPRLSARDDVLVRLAQSAALDGRDEVLLTDELIDALDVGPGEPRLP
                     PHLEVGARVHAAGVDELRRGRFRLEVVSVSRGVGVTSGRFLGVLTPDDRAALAAELSGL
                     PAADGDTVPAQLSFPPLLPESAHVTRTPRVLPTVVSLQEHRSPDADVLAPADLAVGCDG
                     RRMYLADPKRGRRVEPVGMHALNLRTHTPPLVRFLTELPRAQCAQVTVFDWGAAAAMPF
                     LPRLRYGRIVLAPARWRLEATELPGQARPRAEWDAALTDWRARRRLPRRVHLVEDDRRL
                     LLDLDEAAQRTLLRDHLDRVRRAVLVEAAEPGAFGWCDDRAHEVAVPLRATRPSPWPEL
                     PAPTPARALAPVQTQTPAASSVLLAALYGDARRQDTLLSRHLPDLLERLGGPPWWFVRF
                     RDPEQHLRLRIALPTPEAFAETARTVSVWADELREAGLLADLRYPTSYRETGRWGSGAA
                     WDAVEDVFRADSRAVLAQLSQPRRPHRRTLVAAHTLSVASAFLGSTEAGARWLIDHIPP
                     TAPGSVPRPEFTDAVRLADPGDDWAALRAAPGGAAIVQAWADRDEALAAYRRHLPGPHT
                     QGIALDDVLTSLLHVHFVRHIAVHFPEEEVCLHLARAAALARAARTTGKTP"
     aSDomain        complement(15720..15992)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IE283_RS30970_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.90E-19"
                     /identifier="RREFam001.1"
                     /label="IE283_RS30970"
                     /locus_tag="IE283_RS30970"
                     /protein_end="204"
                     /protein_start="113"
                     /score="61.1"
                     /tool="antismash"
                     /translation="VVNNTVTSRGDRLVVPFQSDDRGERPRAVETSLALTEPVRTVLAV
                     ARGPVWGGALVDKLEAEFPEAGPEKARRLLAELVRRRVLVTGLQAP"
     misc_feature    16304..16318
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(16580..16762)
                     /locus_tag="IE283_RS30975"
     CDS             complement(16580..16762)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="IE283_RS30975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_164272930.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5.1e-15, bitscore:
                     48.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSTVVPSSTQVSPQTTPSTPDGFDLDVSLVEVADPAGLVNLTD
                     DNCGSTCGACTTNVA"
     gene            complement(16968..17426)
                     /locus_tag="IE283_RS30980"
                     /old_locus_tag="GCM10010348_62610"
     CDS             complement(16968..17426)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992134.1"
                     /locus_tag="IE283_RS30980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_62610"
                     /product="ATP-binding protein"
                     /protein_id="WP_164272927.1"
                     /transl_table=11
                     /translation="MTSLITLMHSAATGHPAYSQTFPCEPSTAEAGRTLVRDALGIWHL
                     DDLADVTALIMSELIANAVTHTTCRSIRLIVGRPSATRIRVGVVDRAPARLPVLGRAGD
                     VDESGRGLLLIDGIADRWGYDLRGPHRRPWGKEVWAELLTTRGDEGEE"
     gene            17671..18957
                     /locus_tag="IE283_RS30985"
                     /old_locus_tag="GCM10010348_62620"
     CDS             17671..18957
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383502.1"
                     /locus_tag="IE283_RS30985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_62620"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_193486914.1"
                     /transl_table=11
                     /translation="MDATRNIVLEAWMAEHGYSSNSLADAVNSALERLTGRPGGLDGSS
                     VRAWKAGRVMWPKSATRKALEDVCGLPAVALGFVPRGRPSSSPVPPQQEDPDMKRRSLV
                     GGIAAAAAAAAAAPGIAGPRRIGMSDVDRLNKRFTEIIASDHRHGGQLGIEQRAAALAD
                     EALNLQNAGSATQRVRSSLYASAAAFRSSAMWAAIDGRRYDVAKAHMREAQALAEMSGD
                     QAIKFRIWSHTGTMYRHMGRPSDAFAANDVARNLHITRRDPMFASLGMARQAAIHGAAH
                     DRTGTRRAFDQAQEAMLRADPGDYRPVWLLAFYDQAELHSLALSAHLALGDYPTAEYHA
                     HRCLSALRPHMVRSRAITTTRLAHAQLAQGAADAATATAMKVPADAATRHARVTRMLQE
                     FGAALRATALRSSTVQIWTEHTASWRMAA"
     gene            18954..19493
                     /locus_tag="IE283_RS30990"
                     /old_locus_tag="GCM10010348_62630"
     CDS             18954..19493
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337821.1"
                     /locus_tag="IE283_RS30990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_62630"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_193486916.1"
                     /transl_table=11
                     /translation="MTTAPTIQLRTFTTLDTARGDLLDVYADVRAPLLHLPNYAVTAFG
                     ERLDRHGGEPGFTAVLAYSDGTPVGYAYGNSIEHGDRYWQRTGPAPADTYTRRPALALK
                     EIGVRQAWRKTGTARRIHDALLATRDEPFVTLMVNPAAGDGKVHALYRSWGYEDIGQSQ
                     PSPASPVLTVMIRAVR"
     misc_feature    complement(19671..19685)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.02"
                     /tool="antismash"
     repeat_region   19810..20263
                     /inference="COORDINATES: alignment:crt:1.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=171643..171671
                     /rpt_unit_seq="gggaccatccccgcgggtgcggggagcag"
     misc_feature    20089..20103
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.36"
                     /tool="antismash"
ORIGIN
        1 gcgagctcgg cggcctcgtc caccgtggcg ccgtccgcgt cggtggcgcc gatcagcgcg
       61 cgcagaagcc tgatgtggtc gttgtggtgg cgcggagcgg agcgcaggtg ggcgagggcc
      121 gtttcgaggg caagggtccg gacggacggc ggggcctggg cgttactgac gagcgcggcg
      181 aggatgcggg gcgcgtgctt ctcgtgccgg ttgcggagca cccacgtcag ggcggccccg
      241 gccgctgttc cgtagaggtc cgcgcccatc tggcagtggc gtacgaggat gtcgagcagc
      301 gggccggtgt ggggcgattc gtggtgcccc tccgcccagt ccagcgcgga gcgggcgagt
      361 acgtcgctgt cgttgcgggt ggcgtcgccg cgtaccgtca cgagcagcgc cttcgtcacg
      421 gcaggccagg cggcatggtc gcagtgggcc ggcagccatg ccagggtgag gtcctcggtg
      481 cgctgccgga cggcgtcggg cagcgccggc tggctgagca gggtgcgcag caggtgcggc
      541 gagaccgcgg cgggggccgc ctccgcccgc cggagcaacc agtcggctgc ctccgcgcgc
      601 gctgcgccgg cgttcgggct gcccagcacg gacctggcca gttcggcggc gcccggttct
      661 tggtcggcga gccaggagag tgcggtgggc aggagcgggg cgacggcctc cggggtggcg
      721 cgggtgttgc cgatggcggc tcccagcatc ttggcgagca gccggcgttg tccggacctc
      781 ctgaagtcgg ggtggtcgtg gcgatgttcc acccatcgcg cggcgagccg cacggcgcgg
      841 tccgcgtgcg cggagtccag cttgttgttc cgcagcgccg cgcgcacctg tgcgtgggag
      901 gtgggggccg cgatgtcggc ttcggcctcg tcgagcgacg cggtcgtggt cggcagggcc
      961 acggcgtgtg ctctttggcc gagtaccttc cgcagccgcg ccagctgtgc ggggttcgcc
     1021 ggcggagtgg tgtcctcggc gcgggtgagc cggcttcggg cggtgtccgc cgcctgcgag
     1081 agaaccgctg cgggtacccg ggggctgccg agcactgccg tgaggagttt caggtcggag
     1141 ccgtccgggc tggggtgcgt gcgggcccag cctagggccg cgactccgat gcgccccatg
     1201 caggcgtggc tgcatgggtc gcgccgagca gagcgtgcag agtcttcacg gccgtcggcg
     1261 gcgcggggag ccggccgagc cgtgccagcg cgccgtcggc cgcctcgtcg gcggtgtcgg
     1321 aatcgacgcg ggtgctgttc gcgaccatgg tgagcagctg tgcgtccggc cccgccgggg
     1381 cgcggtgcgc accgcggatg atttcctggg cggcccagcg tatgtgcggt gcacctaggc
     1441 gggaagagtt cagcacgctc cgcagcagcg gcagggtgtg cgcgtggtgc ggtctggccg
     1501 cggcccactg cctcaccagg acggcggcgg cgtcgacgtc ggccgggagc atccacgggc
     1561 cgccgatcag cgcccgtagc aggagcggtg cgtcgtggtc cagggggtcg gcgcgcaggc
     1621 gttcgagggc atggcgggcg gcggcgtgca cgaagtcggg gtccgcgcgg atgctgacca
     1681 ggcgccgcag cagcatctgg gccgtggggg tcgcggggtg tgcgcggatc cagtcgagga
     1741 cgaaccacag cacgtcgacc ggaccggtgg cgtgcgacca gccggtgacg aaatcgtgca
     1801 ggaccacacc ggcgtcgacg ccgagccgtt ccaccgtctc cttcagcgtg tccagggcct
     1861 gcgtccggca ttcggcgggg aacgccgggc tgcgcagcac catggccgac aggcgtcctc
     1921 cggggcgcgg gtctgccatg gtgcggaccc attcctgggc gcgcgcgtga acgagttccg
     1981 cctgaggggg agcgagcccg gcactgtcga gcagcccggc gagcggggcg accactccgg
     2041 tgttgtccgg gtggcgttcg atccaggcga ggcacacggc gacggcctgc tcgcgccgtt
     2101 cgtcggagag caagggacgt tcgacggcct tggtcagcag gtccagatgg acgagttcgg
     2161 tccggtgggc cagccagtcg agggcggcct cctggacccg gtccgtgctg agcggtgtga
     2221 ccgcggtctc gaacagcagg ttgagcaggg cgacggcacc cggaccggtc cgtccgtcgg
     2281 cgagggcgtg ccgcgcgcgg gccacgaacg cgtcgcgcaa ccccgcgtcc cgcagagctc
     2341 cccgggcgag ttcctggcgc agcccgatgc cggacttgcc cggtgactcc acgagctgcc
     2401 gcaccaggca gtccagtacg gccgcggccg gttccccgtc gccggtcacg gagttcaggc
     2461 agcgggccat ggtcaggagc acttggaccc gcgcgacctg ggcgagtgtg tctccgtacg
     2521 tgttgaacca gtcggccgcg gtgcgcagat gtcgtgctgt ggcctcgcgg gagacccccg
     2581 gggacaggag cagccgggtg aggaaccagg cggcgtccgg gtggtccggg tgggcggcga
     2641 gccaggtctc caggaggatc agcagccgct cgtactgggg gttcctcggg gtgagccggg
     2701 cgaacagggg gtggaagacc tcggcggtcg gcaggcgccg cagatgggac tccagccagg
     2761 cgagggagtg tgcgacgacc gtcgtctgct ggcccgcgga cagtctgggg ctgctgagca
     2821 ggaccggcag caccgtgcgc acccggggat gggctccgtg gacgctcagc cagcgcaccg
     2881 cgttgtcggt gacggttccg ctctcttcgg cggtgagcag atgcgcttcg aggagcggcc
     2941 ggacgacgaa accggcgggc agggcagtgg cgtgcccggc gaaccagtcc gccgtgatct
     3001 cgacggaccg ccggtcgagg tccgtcgtgc cggtggggtg ggcgagcagg ccgcgcagca
     3061 ccacggtgac gtcgtccgcc gtctcgacgg cgtcggaggc ggcccaggac tgggcgcggc
     3121 gggcggcggt ggcgcgctgg gcgtggtcga ggtcggtgcg cctcagcagg ccggccagga
     3181 cgggctccac ggcggtggtg ttcccggcga gccacaccag ggcggcggtg atggtcggca
     3241 gtgcctcccc ggcgggcagt ccggtcaggg cgtagcgcag gaagcggctg cggtcggcgt
     3301 cggggaccgc ggtgcgcagc cagggttcga cgacggtgtc ccaggcctgg ccgaccggac
     3361 tctgccacgg ctccgcgtgc agcagggtgt agagcgtgtg gccgccctcg ggcgcgctgg
     3421 cgcagacctc gccgatgcgg cctgccctgg ccgtgatcca ctcccggcag gccctgccga
     3481 actgttcacg ctgcgcggtc ctggccagtt cgccgtacag gcgggccgcg ttgcccgcga
     3541 ggtggtcgag cacgtcgggc tggtccacgg tccggtcgag caggccggtc agctcggtgt
     3601 cgcggacccg taggccggtg cgggggacga cgactgcgcc gagcagttcg tcggtcacga
     3661 ggtcgtgggt cacgtccaga cggtcgccga cctgttcgaa ccagcccatc accagcaggt
     3721 tgtcgatcag ggcgcgggcc cggcccgcgc gtggcgcctc gtccaacacg ggctgcacca
     3781 gcgtctccag ccgctctttg ggcagtgggc aggccgcggc ggccagcgcg caggcgcgga
     3841 cggagtggct gatgtcgtcg ccgccggaca gccagtccgc gtcgtcgccg ggggtcctgg
     3901 gcgcgggcac gacgccgtcc tgtacgagac tggcgcgcag ccagcgcatc agcctgctgg
     3961 ggccccggcc cggggttgcg tccttgcccg cgcggatccg gcgttccgcg tcctgggcga
     4021 tgagcagtgc gatgaccggg cggtgtccgc agatctccgc catccgggcg ggccccagcc
     4081 gttgcagggc caggggggcg acggaggcga agacgcgttc cgcgatcgcg gcgtggtagg
     4141 cggagtcgag gcacagttcg acctcggtca ggtcgtcgac ggctccgcgg gcgaccagat
     4201 gaggcactct gctctgccgg ctggtggcga gtacggcgaa gtgcccggcg gcgctctgca
     4261 gtgccgggac ccgctccagc agtccggaca ggtccaggcc cgcgcagacc tccaggtagt
     4321 cgaccagcag cagggtccgg gcggcgggtt cggcgaggat ggcctgctcc acgtgggtgt
     4381 tggcggtctc gctgtcgggc cgtacgtaca gcacacgcca gtcgtcgcgt tcggccagcg
     4441 ccgcgacttc caggagggtg cgtgtcttgc ccgctccggc gggcccggtg agcaggacgc
     4501 cggggctgtc ctccaggagc ttgaggacgt tcgcgggcgt ggcgggatgg ccgggcccgg
     4561 gggcgaggaa ggccagctcc gcctccagca gatggcggga gcgcgcggtg agttctccca
     4621 ccgcccgtcc tgcggacacc acccggtccc ccgcggcgct gtcctgcggt gcggcggccg
     4681 gtgggggctg ccacggttcg atgccgtggt ggcgcatgat cgccacgtcg aaggcgaacg
     4741 ccatcggccg gtccgcggcc aggatccgtc gacgtgccac gtcgacggcg gtgtcgaagt
     4801 ccaggagccc gtcgtccgta cgccggctgg gggcgagtgt gtcctccccg gggtggagct
     4861 cggatccgcc ctcggggctg cctgtgatgc gggcgaagcc cgtgcattcg acggggacga
     4921 acgcgtggga ttggacgagc gcacggacca cggacggatc gtggaccacg ccgtcatgga
     4981 actcctcgta gccgggccgg taaccggccc actcacgcag tccgtggtcg cggcagacca
     5041 gcgtgacggc gtgctcgccc tgcgccacga cgaccggcag gagttcgtag tcgaggagca
     5101 gtcccgcgta cagcagggcc aggtccaggc aggtgccgcg gcggcccggg gagccgagga
     5161 tctcggcagg cgtacggatg cgctggacat ggtccgacgg ggtgtagccc tcgacgtcgt
     5221 agtacaggcc ctgcagggcg agctgcccgt agagcgcgcg ggcgagggcg agagggccgc
     5281 cggggccgtc gccgataccg cgccggtcca gcccgggggt cagcaactgc tcggccccgc
     5341 tgaccacgta gcgggccagc cccgactgat cggaggtgga ccacagcggc caggtcatgc
     5401 accgtcctcg ctgacctcga acaggtcgtg caccggcggc ggcagcgccg tggcgccgcg
     5461 ggcaacgacc tccagccggt acgcgccggg tgccaagggc ggcagttcgg cgcgccatgt
     5521 ctcctcggtg cgttcaccgt ccggggcggg caccaggtcc acggcgtggc gggcgccgga
     5581 ctcggtgtgc tcggcgacgg cggtgacctt ctcgggccgg tccggcgcga acacctccgc
     5641 ctttacgacg acgggctcgt cgccggcgta ctggtcctcg acgtccacgc ccagggcgag
     5701 ctggccggtg tccaccaagg gctcggggcc ccggagcttg gggcggacgc gggcctgcat
     5761 cttcgtcagc cggcccagca gggtgttcag gacgtgcggg ttgttgtgga ggttgctgtg
     5821 cttctcggcc tggaacacgt cggcgaagac gtccagcggg tcggcggggg ctgccgagga
     5881 aatgccgacg gtgccgtcgc cgtcacggtc cccgtcgccg aagtagcggt gcacgccgtc
     5941 cgggaggtca cggctgaggg acacgccgga accgtcgtac acggcggact gccaggtgcg
     6001 ctgatgggtg ccgaccacgg gcaggacggt gtaccggaag cccccgcgtg ccacggcctt
     6061 cgccccggtg gtgatctcgc ggtggaactc ggccgcgtcg gcggcgaggt gggggtcgac
     6121 tccggtgatc ggaccgacct cggaaatccg tcggggcgtc ccggtcccgg ggagcgcggc
     6181 cgtcgcgtca tggatcaccg ggtcggccgg catgagctga tggacggacg ggaacgtacg
     6241 catcacgtcg gtcaggtcca gggtcgcctt ccggtagccg tcggcgagat agccgagcgc
     6301 gtccagcgaa ccgccgaacg gggtaccgaa ggtgacgagc gcccgggtca ggcggtggcc
     6361 tccgagcacg tccaggaagt accgggccac caggccgccc atgctgtgcg ccacgacgac
     6421 cagttcggcg tccgggatgt tcgcatggct ccgccagtcg gccagggccc gctcggcgac
     6481 ggtggcgagc cggcgggcgg tgacgcggtt gtccagccgc cagtcgtagg ggaactcgat
     6541 gaggttggac ggcggcagcg cctccgtgcc ggtcgccacc gcatgccgca cgtcgaagtg
     6601 cgcggccagc gcctgggtca gccgggagta gccgtcgatc ttcacaagtc ccggcacgag
     6661 gcaggcccgc ggcagcagcg cgtccgcggt cagggggccc tcgtcgaggg cgagggcccg
     6721 cacggtcttc tgccgttgca gcacggactt gccgatcagc cggtatgagg cgtcccacac
     6781 gggggttccc gcacgactga gaacggaccc tgtgatgccg ggcaggacga tgatcacgtc
     6841 ccgaagccgc tgtctcatcg cactgctcca ggtcccccgg cgccacgtct gatcggtgct
     6901 gcgtacagcg caggctacgg gatcggccgg gacggggcgc cctgttcagc aagtcgtcaa
     6961 gtggctctag tgtcagcact gttcaccgtg cgactgctgg tgcgggcggc ggtcacggag
     7021 ccgacgcgag ctcgacagcg ccgggaaggc ccagatcgtt catcagctcg gtgaagggcc
     7081 cctcgtcgag gctctcccac gagcgcaggc cctgctcggt ccgggaccac tgcgccgaca
     7141 tggagactcc tgccgtcacg acccggacga gggcacccgg cgcccgggtg tcgggtggaa
     7201 cgtcgcgcgt cgagtccggg cgcgttcact cacaggctct ggtcgcccag gtcctcgggt
     7261 tcgtcgacca ggagcgccgc agcatcgtcc agactgagcc atgcctgtca gcgccggccg
     7321 tcggtgccca gtccggtcac gaaggccgtg tcactgtcgg agacgccgac gacgcaggcg
     7381 agcctactgg cgagcttggt gggaccatgc ccgcgggtgc ggggagcagt cctcgagcac
     7441 gatccgcttc gcgtacccgt tggggccatc cccgcgggtg cggggagcag cagaccatgc
     7501 gcgtcatcgt ggtcttgtcc gaggggccat ccccgcggat gcggggagca ggagctgccg
     7561 ctggggtggc tgacgggtgg gggggccatc cccgcgggtg cggggagcag tccacgccgg
     7621 tcaaggtgac ctcgtgggag caggggccat ccccgcgggt gcggggagca gtaaccggcg
     7681 ctccattcgt tcgcggcgcg ttcggggcca tccccgcggg tgcggtgagc agggagtcac
     7741 cgaccgcggc gaggccgacg agctggggcc atccccgcgg gtgcggggag cagctcagcg
     7801 ggcaccagct gcgcgtcctg aaccaggggc catccccgcg ggtgcgggga gcagacggac
     7861 gacgtggcgc cgttctcgga gccgcggggg ccatccccgc gggtgcgggg agcaggctgg
     7921 gctgatcctg ccactttgcg caacagtcgg gccatccccg cgggtgcggg gagcagaccg
     7981 gcgtgctctg ggcgctggag gcgatcgtgg ggccatcccc gcgggtgcgg ggagcaggcg
     8041 ccgaacggga cttgcaaacc ggccgaggtg gggccatccc cgcgggtgcg gggagcagtt
     8101 cgtgttgggg tcgacgttgg agcgggtgtc ggggccatcc ccgcgggtgc ggggagcagg
     8161 agccggggat cgtcgggggt ggtgtcgtcg agggaccatc cccgcgggtg cggggagcag
     8221 actgattgac ctgcgagttt acggccgcag ggacgcgttt tcagcaagct tggcagattc
     8281 cggcaaatga gacatggcgc ggtgcccatc catagggcac ttcagagcgg gccaatcgtc
     8341 catgctgccg gccagaaccc tcctcactca ggcctggatg cacacgagct gggactgctc
     8401 aggcgtcagg gccagctttg ccttcccagc cacgcatagt gcgggctgaa cacggcgttc
     8461 ggggagaacg tcttcgtcaa ccaggggatg caccttcatg gacaaggaag gcatccgtat
     8521 cggcaacggc gtcatgatcg ccccgaaggt cagcctcatc accggaggcc atccactgcc
     8581 cctggccgag cgccgcgagt acctctcctc cgctccgatc gtcatcaagg acgacgtctg
     8641 gatcgggacg gctgccgtga tcacacaagg ggtgaccatc ggtgccggtg cagtggtcac
     8701 tcgtgatgtc tctgccggca ccgtggtcgc gggagtgccc gcccgggtga tcaagaagat
     8761 cgactgagcc cggtcgtgct gccgggcccg ctcctagccg cgcttctcag gtcgagccct
     8821 cggccgaggc ttgtccggat gacgctgtct ccggtacgcg cgaccgaagc gaggtcttct
     8881 cgcagctcgt cgggcatccc ccctgccccg agggcgcagg cgcgcaccag gtcgcggcaa
     8941 tcctgcactt gccggcctga ggccatctcg gtgaacaggg tgctggccag cgtctcgcgg
     9001 gccgcatagc cgtcctgggc cttcctagac ctgcggtgaa ggtcgtcgac gatgcggcgt
     9061 gcggaaggcg tctcggtgga accggtcgcg tcgagggccg tgaggccgag gcggatgtcg
     9121 aagacggtca tgcccgtctc ggtcttccgg ccgaggtacg ccgtcgccag gtccgcggct
     9181 tggcggtcga ccggttgtcc tgcggcgcgg cggcacagga cggtcagaca ggccgtgacg
     9241 gcctgttccc acggggcgcc gggcgtcgtg ccggcgagga gggcagcggc ccgggcggtg
     9301 ttgccggcgg tgagtgcggc gactactgcg gtctggcgtc cgtcgagcat ccgactgccg
     9361 acgccgcgat gggcctcgat gtgggcttcg gcctcggtcc accgtccctt ggcggtgagg
     9421 gtgcgggtgc cgtcggcaag gagcacacgc cacagccacg cgcggacctc tcgacggtcg
     9481 tcgtcggtcg tggtgaggtc cgacggtacg gcgatgccct cgaaccgggc ggccgtaccc
     9541 gcctcgaccg ccgcgtgcag ggcgagcagc cgccggcgcc cctcgtccgc gtctccggcg
     9601 cgtatccgga gacgggcgag gttgacgatg ggctccaagc cccggatcgc gctcatgccg
     9661 ggcagcgggc aggcgtggag ataggcggcg gcgtgccggc ggcacagcgc gccggcgagg
     9721 gcagggaggc cgacgtcgga ggcgatgagc gcggcctggt tgcaggcggc cgatgcgagc
     9781 ccctggtcgc tcttctcgac cgcggcgtca gcgagttcga ccaggccgcg cacgcgctcg
     9841 ggcagaggcg gacagggagg ccggaaccgg gcgacgagcg ggaagcgttg ggctgtaggt
     9901 ccgtacgggt ccatgggtcc cccgggcgtg agtgggaggt ggtgctgggg cggcggtgcc
     9961 cactgacaac gtcggccggg gccgctgtgc gggcgcggcc tcagcgccag tcgacgacga
    10021 tgcggttcag cggggtgtcg agagtgaaga ggccggggct cggctcggtc gtgggggcgt
    10081 cgagggggag gagctcgaag gtggcctcac gaccgcggta ctcccggtcc caggtgcgaa
    10141 cggcatcggc gacccgcgcg gccagctcgt cgcctcccgg accgtggccg atgacgccga
    10201 actcccagag tttgccgccc tccggtgtct tccgttccga cacgcgccgc gcgaggtaag
    10261 cgacggcgcc cttgtcgacg accaccgagg aggagggata ggggtcctcc gtgagcaaag
    10321 tgcccttggc ggtcttgggg aacagcatcc ggatcaggcc ggagggcaga gagcagctca
    10381 cgaacagctc catccactcc ggcgactcca tgccgcggac cgtcatgccg gtccactcct
    10441 cggtgcgtgg ctggtagagg acgccggtga gggcgtcggc gtcgatgttc tgcccggccg
    10501 gcacctgcag ccgtacggtg ccgtccgtgc tgagggggac gacgcgacgg gcgtcgtcgg
    10561 cgacgccgcg ccgcaggggc atgaaggtgt tcatctcgct gccgagggag acccatcggc
    10621 cgtcgcgctg ctcgtaggcg atcgagcggg acacggtgcc cttgagacgc tggggcacga
    10681 ggaggcgtcc gccgggcgcg agctgccgca gccaggcgtg cggcactccg tgcgcgccga
    10741 cggtggcaac gatccggtcg tacggtgcgc cttcggcgtg gccgagggcc ccgtcgcagg
    10801 tcaccgccgt gacgttgccg atcccggcgg cggcgaggtg cgcgcgggcg cccgccacca
    10861 ggtcgtcgtc gacgtcgagg gtggtcacgt gtccgctctc gcccgtcaga cgggcgagca
    10921 gagcggcgtt gtagccggtt ccggcgccga tctcgaggac gcgctcgccg ggacggacat
    10981 cgagctggtc cagcatgagg gccacgacac tcggctggga ggcgcacgag atcgaggtgc
    11041 cgtcggtgtc gtacttgatg tgcaccggcg cgtcggcgta ggcgtcctcg agcgacgcgc
    11101 cgggcacgaa cacgtggcgc ggcacggtcc gcagggcgtt ctcgacggca ggcgtacggg
    11161 cgtgcccctg cgcgcgcagt gcgtcgacca gggcgtcgcg gaggtgctcg gcccccaccg
    11221 cggggacgtc ggtcgtggtg atcgtgtcgt tcgccccatg gacgctgtcc gtgccgggcg
    11281 tcgcctcggc gggcggtgtg gcgttgtcgt tcgttcccat gactacctct cgtgcgatgt
    11341 cggacagggc gctctggtcg tccctgagga gaccggcgcg gttggaatgg aagatcgtgt
    11401 ggtgggcgat gacggctcgg agaccgcggg tgagggcgcc gcgaccggcg agggcggcca
    11461 gctcggcacc cgcccgctcg aaggcgtcca cccatccgcg gttcccggcg agcggtccgc
    11521 tggggcggca cagacagtgg gcgtccacgg tcatcagctt gcgcatggcg cgcgcgagtt
    11581 cgtcggcccg ctcggaaggc gggcggccgg tcgacggccg gagggcggcg accttcgccc
    11641 agacgtcgcc ctgctcgaac cagtcgagtt cggccgcccg catcatcgcg ctcgccagca
    11701 gcacggtggt ctctcggcgc ccgaggcttt ccggaccggg ccggtgggtg agcaggtgac
    11761 ggctgtcccg gtggaacagc tcgtgggcga cttccatggc ctcggttccg ccgaaggcct
    11821 cggtctcggg ctcgtagacg cagggcagcc acgacacgac cgggccgccc tcctgaacga
    11881 ggtcgctcag caccgcttcg acggcgggtg acggctcgtc ggcgcggtat cgcagcggcc
    11941 agggttgctt gttcatgaac caccagcccg tgagctgccc gtcctgctcg gcggcgagga
    12001 ggacgggggt gatgcgctcg gagacggcgc gctgggcgct cgcacggtcg gcgaaggtga
    12061 tgttgtgctg ctgccagcgg tcggggggca tgcgggtgtc cttcggtcgg tggtcggtca
    12121 ggcgacgagc aggcaggcgt cccaggcggt tcggggcggt acggcggcgc cggacgagag
    12181 gaaggccaga gcgatgccgg ctgcaccgtc gagcaggccg gggccgtacg cctcgtgctg
    12241 gatgagcgcc gtggtggtgt gcgcggggtc ggtgccgggc ggatgcacgg cggccaggag
    12301 tgttgggatc gcggcacgga gccgtccggc gttcgaggga tgggcgtcgt cggccgcgca
    12361 ggcggcgatg tgagcgaggc cggcgaatcc gtggcacagg gccttgtccg tcgtagcgtt
    12421 gagctgggcc gggtcggtga gggcagccac gagggcgttc tcggcgtgca gccggcgacg
    12481 ggtgtcgccg agggcgagtg aggcgagttg cagggctcgg gcgagaccgg cagtgccgta
    12541 gcaccaggac ggccgccgtc gtgcgaaggg ggccaggcgg tcggcgcgca actcgggccg
    12601 ggtgacccag tacggccatg ccggaccgcc gccggtgtcc tcctgccagt ggtccagcca
    12661 ggccaggatc cggcccgccg cttcctcatg gccggcgacg aagatgccgt gccgggcggc
    12721 gagcgccagc aacgccagta caccgccgat gccgtgcgcc atgccgctgt tggcgtgtcc
    12781 gccggggaag cgttcgtcgg gacggcccga cggacccgtt ggcgtccacc agcccggcag
    12841 ggtttctccg tcgtgggtga tcgggtgggt gaggcgtacg cagtagtcga ggacgtcgcg
    12901 caggacggag gagtcggggg cgcggcgcag gaggtgggcg ccgtagccgg tcaggccccg
    12961 gacggtgtcg aactcggcga gcgccgggtg gcgtccggtg tcgatgcggc ggtgtgcggc
    13021 gtcgaggcgg cagctcacat cggccgccgt ctgtcggtcc agggtggcga gagcgcgccg
    13081 gtaggcgccg ggcaggtaat cgacggcgca ggccactgcg tacgcgaggg cgggcgcccc
    13141 gtagaacggg tggctgtccg ggccgctggt gagcggctcg cgggaggcgg cggcgagcca
    13201 gtcgtgggct cgctgccacg ggccgaggcc ggccgcggcc cgcacgatgt gcagaagtgc
    13261 gatgccgggg agaccgaggg caaggtgctg ccggtgtgcg gtcggcaacg acacgctgcc
    13321 ggggtcggcg agatgctcgg cgacggcatc ggccaggccg agtgtgctct ttgcggtctg
    13381 tgcggtcatg gtgtcttccc ggtggtgcgg gcggcccggg ccagcgcggc ggcgcgggcg
    13441 aggtggaggc agacctcttc ttcggggaag tgcaccgcga tgtgccgtac gaagtggacg
    13501 tgcagcagcg aggtgagaac gtcgtcgagg gcgatgccct gggtgtgggg tccgggcagg
    13561 tgccgtcggt aggcggcgag cgcctcgtca cggtccgccc acgcctggac gatggccgct
    13621 cctccggggg cggcgcgcag ggcagcccag tcgtcgccgg ggtcggccag acgtacggcg
    13681 tcggtgaact ccgggcgcgg tacggacccg ggcgccgtgg gcgggatgtg gtcgatcagc
    13741 cagcgcgccc cggcttccgt gctgccgagg aacgcggagg cgacggaaag ggtgtgcgcg
    13801 gccaccagcg tgcgccggtg cgggcgccgc ggctgggaga gctgggccag gacggcccgc
    13861 gagtccgcgc ggaacacgtc ctcgaccgcg tcccaggcgg cgccgctgcc ccagcgtccc
    13921 gtctcccggt acgaggtggg gtaccgcagg tccgccagca ggccggcctc gcgcagttcg
    13981 tcggcccaca cgctcactgt ccgggccgtc tcggcgaagg cctccggcgt ggggagcgcg
    14041 atgcgcaggc gcaggtgctg ttcggggtcg cggaagcgga cgaaccacca cggcgggccg
    14101 ccgagtcgtt cgagcagatc gggcaggtgg cgcgagagca gcgtgtcctg gcggcgagcg
    14161 tcgccgtaca acgcggccag cagcaccgat gatgccgccg gggtctgtgt ctgaaccggg
    14221 gccagggccc gcgccggggt gggggcgggc agttcgggcc acggcgacgg ccgggtcgcc
    14281 ctgagcggca cggccacctc gtgtgcacgg tcgtcgcacc agccgaacgc ccccggttcc
    14341 gcggcctcga cgagcacggc ccggcgtact cggtcgaggt ggtcgcgcag cagcgtccgt
    14401 tgggcagctt cgtcgaggtc gagaaggaga cgccggtcgt cctccacgag gtggacccgc
    14461 cggggcagtc gccgtcgggc ccgccagtcg gtgagggcgg cgtcccattc ggcccggggg
    14521 cgtgcctggc cgggcagctc ggttgcctcg agtcgccagc gggccggggc gagcacgatg
    14581 cgcccgtacc gcaggcgcgg caggaacggc atcgccgccg ctgcgcccca gtcgaacacg
    14641 gtgacttgcg cgcactgggc gcggggcagc tcggtgagga accgcacgag cggtggggtg
    14701 tgcgtgcgga ggttcagcgc gtgcatcccg acaggctcga cgcgccgacc gcgcttcgga
    14761 tcggccaggt acatgcggcg gccgtcgcac cccactgcca ggtccgcggg cgcaaggacg
    14821 tcggcgtcgg gtgatcggtg ttcctggagg ctgaccacgg tcggcaggac tcgcggggtc
    14881 cgcgtgacgt gggcgctctc cggcagcagc ggcgggaagg agagctgcgc gggcacggtg
    14941 tcgccgtcgg cggccgggag accggacagc tcggcggcca gggccgcacg gtcgtccggg
    15001 gtcaggacgc cgaggaagcg gcccgaggtc acgccgacgc cgcgggacac gctcacgact
    15061 tccagccgga accgcccgcg ccgcagctcg tccacgcccg ccgcatggac ccgcgccccc
    15121 acctccaggt gcggcggcag gcggggttcg ccgggtccca cgtctagggc gtcgatcagc
    15181 tcatcggtga ggagcacctc gtcacggccg tccaacgcgg cggactgcgc cagccgtacg
    15241 agtacgtcgt cccgggccga gagccgaggc cggcggggac tgggcgagga gcccgggtaa
    15301 ccctccgggt agccgatgcc gctgtcgccg acgacttcca ggagcggcac catcgtgccg
    15361 atgccgtacc gctcgtaaaa ccgctggtgg tacgcgcccc acgccgcggt gccgtacgga
    15421 cgggcgctga cccgggtcag gatcagcgcg gcgcgctcgg tctcgcgggc gaccgcgtcg
    15481 ggcagtgcga gctgcgcgtc caggcgcagg tcgagcgcga cggggtggcg gcgcaggccc
    15541 ggcacgaggg ccctcatccg ggctgcgaca ctgtctcgcc caccacgcga agcgcactgc
    15601 cccagcgcgg cgtggatctc ccccagctcg cgcacggtcc cggcgagagc ggggagggac
    15661 tcggcgtcgg ccgtgcggag ccggtcgagg aggtgtccga gggcgtcggt ctcggtactc
    15721 ggcgcctgca ggcccgtgac cagcacacgc cgtcggacca gctccgccag cagccggcgc
    15781 gccttctccg gcccggcctc ggggaactcc gcctcgagct tgtccacgag tgcaccgccc
    15841 caaaccggtc cccgggccac ggcgaggacc gtgcgcacgg gctcggtcag ggccagggac
    15901 gtctcgacgg cgcgcggccg ctcgccccgg tcgtcggact ggaagggcac gacgagccgg
    15961 tcgccacggc tcgtcacggt gttgttgacg accaagggca gtcgtcgaag gaagtctggg
    16021 caggactcca actgctcaac gacagcggcc agccactcgg cgccggcccg gccgacgacc
    16081 acgtgctcct cgccccagct cacgcgcggc cgtgggtcga accccgcggt ggtcacaccg
    16141 gcgaagagcc cgaacggcgt cgctcggtgc cgggcacgca gcagatagcg ggccacggac
    16201 agtgcagccc gccgcgcctt tcgcgggggc ggttccgggg ccgcgcacac actccgtacc
    16261 cgcgcagcca gcaccgggct ggcgtgttcc agggcttcga cgaggtcgtc gtcggccagg
    16321 accgcacgca gccacgcggt gcaggcggcg actccaccga cggagcgatc gccaagatcg
    16381 ggaaagagag ggtacggcgg cgccgggcgg gcaacggctc gtacgagagc ggtcgtgccg
    16441 gagcggaacg ccgggtactg atcagccacc actacctccg tgtgcgcgac ttggacggct
    16501 ggtgccgccg cgcccacagg acgcggcagc accagcccgc ggatacgcag agcatccgga
    16561 tgcggcttct cgggggtgct caggcgacgt tggtggtgca ggcgccgcag gtggatccgc
    16621 agttgtcgtc ggtcaggttg accaggcccg ccgggtcggc cacctcgacg agggagacgt
    16681 cgaggtcgaa gccgtccggc gtgctcgggg tcgtctgcgg gctcacctgc gtactgctcg
    16741 ggactaccgt gctgcgggtc atttcgaatc cttcggtggt gtggttggaa ggttgctgtg
    16801 tgatgccgcc cgtgcccggc cgtacggcac ggcgccccgg gtcggagagg tcggaggcgg
    16861 gagtccggtg gggagcggcg gtggccgacc gccgctcccg caggcccgtg cggaggaggc
    16921 aagggggcgg ggcccgggaa gccgagggcg gccactgcgg cggaggctca ctcctcaccc
    16981 tcatcacccc tcgtcgtcag gagttccgcc cagacctctt tgccccacgg gcgcctgtgc
    17041 gggccacgga ggtcgtagcc ccagcggtcg gcaatgccgt cgatcaggag caggccgcgc
    17101 cccgactcgt cgacgtcacc ggcccggccg aggaccggca ggcgggcagg cgcccggtcc
    17161 accaccccga cacgtatccg tgtcgcgctc ggccgcccga cgatcaggcg gatcgaccgg
    17221 cacgtcgtgt gcgtgacggc gttcgcgatc agttccgaca tgatcagcgc ggtgacgtcg
    17281 gcgaggtcgt ccaggtgcca tatgcccagg gcgtcccgaa cgagcgtccg gcctgcttcg
    17341 gccgtggacg gctcgcacgg gaaggtctgg ctgtaggcgg gatgcccggt ggctgcggag
    17401 tgcatgagag tgatcagact cgtcatcggg gttggaccct cgcgtcgtct cggtgcccgg
    17461 cccaccaccc tgagaaagtc gcaccaggag gaggccggac cgtcaccggc cgcccgctcc
    17521 gaaggaaggg gcgagcggcc gacaaccaga caactcgctt gcacaggcgg gtggttaggg
    17581 cgatccaccg cccgtaccga ggaaacccta gggcgatttg actccccctt tacctggtgg
    17641 gtgaggggac gtcagggcta ccgttcgggc atggacgcca cgcgcaacat cgtccttgag
    17701 gcgtggatgg ccgaacacgg ctacagctcc aacagcctcg ccgacgccgt gaactcggct
    17761 ctcgagcggc tgaccgggcg gcccggcggg ctcgacggct cgtcggtccg cgcctggaag
    17821 gcagggcgtg tcatgtggcc caagtcagcc acccgcaagg cgctcgagga cgtatgcggc
    17881 ctgcccgccg tcgctctggg gttcgtgcca cggggccggc cctcgtccag ccccgtccca
    17941 ccgcagcagg aggacccaga catgaaacgc cgttccctcg tcggcggcat cgctgcggct
    18001 gccgcagcgg ccgcggccgc gcccggcatc gcaggacccc gccggatcgg catgagcgac
    18061 gtggaccggc tgaacaagcg tttcaccgag atcatcgcca gcgatcaccg gcacggcgga
    18121 cagctcggca tcgaacagcg ggcagccgcg ctcgcggacg aggctctcaa cctccagaac
    18181 gccgggagcg ccacccaacg tgtacgcagc agcctgtacg cctccgcggc ggcgttccgc
    18241 tcgtcggcga tgtgggccgc catcgacggc cgccgctacg acgtcgccaa ggcgcacatg
    18301 cgtgaggccc aggccctcgc cgaaatgtcc ggtgaccagg ccatcaagtt ccgcatctgg
    18361 agccacacgg gcaccatgta ccgccacatg ggccgcccct ccgacgcgtt cgccgcgaac
    18421 gacgtcgccc gcaacctgca catcacgcgc cgcgacccga tgttcgcctc cctcggcatg
    18481 gcccgacagg cggcgatcca cggcgcggcg cacgaccgca ccggaacccg ccgcgcgttc
    18541 gaccaggcgc aggaagccat gctgcgcgcc gaccccggcg actaccggcc ggtgtggctg
    18601 ctcgccttct acgaccaggc cgaactgcac tccctggccc tgtccgccca tctggcactc
    18661 ggcgactacc cgaccgccga gtaccacgcc caccgatgcc tttccgccct gcggccgcac
    18721 atggtcaggt cccgggccat caccacgacc cgtctcgcgc acgcccagct tgcccagggt
    18781 gccgccgacg ccgccacggc caccgcgatg aaggtccccg cggacgccgc cacccggcac
    18841 gcccgggtga cgcgcatgct gcaggagttc ggtgccgcgc tgcgcgccac cgcactgcgc
    18901 agctccaccg tgcagatctg gaccgagcac accgcctcct ggaggatggc cgcatgacca
    18961 cggcgcccac catccaactg cgcacgttca ccaccctcga caccgcccgc ggcgacctcc
    19021 tcgacgtcta cgccgatgtg cgtgccccgc tcctccacct gccgaactac gcggtcaccg
    19081 cgttcggcga gcgcctggac cggcacggcg gcgagccggg attcaccgct gtcctcgcct
    19141 actcggacgg gactccagtg ggctacgcct acggcaactc catcgagcac ggcgaccgct
    19201 actggcagcg caccggcccg gcgccggcgg acacgtacac caggcgcccg gccttggccc
    19261 tgaaggagat cggtgtccgg caggcgtggc gcaagaccgg caccgcccgg cgtattcacg
    19321 acgccctcct cgccacccgc gacgagccct tcgtcacctt gatggtcaat ccggctgcgg
    19381 gcgacggcaa ggtccacgcg ctctaccggt cgtgggggta cgaggacatc ggccagagcc
    19441 agccgtcacc ggcgtcgcca gtcctaaccg tgatgatccg cgccgtgcgc tgatcgcggc
    19501 gtgtttccag ggtgcgccca cggctggccg agggccctgc tcccgagagc tgagtcgcac
    19561 cgtctcgcgc tcgaacagtg acgcaaatga cggccaccgg ttggcggccc cctcccccgg
    19621 gcccgcggcc tcccagcact gttgcaccgg gctcctcgaa ctgcgcccat ccgtacatga
    19681 tgtggcggcc tcggtcatca agagcggctc ttcgcgggcg gtggcacagc gatggcctac
    19741 gcgggctggg tctcttcgtc ttccgacagt tagaccatgc ggcagcacgc gtctcgacag
    19801 cccgctgacg ggaccatccc cgcgggtgcg gggagcagct ggcggagcgc ggctatgcgt
    19861 acggccttgg gaccatcccc gcgggtgcgg ggagcagaac ggccgggact acggcacgtt
    19921 cacgctgccg ggaccatccc cgcgggtgca gggagcagtg ccttcagggc catcacgccc
    19981 ctccttatct gggaccatcc ccgcgggtgc ggggagcagg acgcggcacg gcaccagaag
    20041 agtgactacc ggggaccatc cccgcgggtg cggggagcag tcgctgccgg gatttcgtgt
    20101 tctctgggtg gagggaccat ccccgcgggt gcggggagca gtgccctgcc ggactcctcg
    20161 gcaccctcgc cgggggacca tccccgcggg tgcggggagc agtgtcctcc ctcgtggtct
    20221 tactgctggg cccagggacc atccccgcgg gtgcggggag cagtgccctg ccggactcct
    20281 cggcaccctc
//
