LOCUS       NZ_BMVQ01000005        22697 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces anthocyanicus strain JCM 4739 sequence05, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVQ01000005
VERSION     NZ_BMVQ01000005.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces anthocyanicus
  ORGANISM  Streptomyces anthocyanicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces violaceoruber group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 456916)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:14:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,934
            CDSs (total)                      :: 7,858
            Genes (coding)                    :: 7,681
            CDSs (with protein)               :: 7,681
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 177
            CDSs (without protein)            :: 177
            Pseudo Genes (ambiguous residues) :: 0 of 177
            Pseudo Genes (frameshifted)       :: 73 of 177
            Pseudo Genes (incomplete)         :: 130 of 177
            Pseudo Genes (internal stop)      :: 16 of 177
            Pseudo Genes (multiple problems)  :: 37 of 177
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:48:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 382696
            Orig. end                         :: 405393
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVQ01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22697
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22697
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22697
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12697](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12697
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(29..823)
                     /locus_tag="IE283_RS16970"
                     /old_locus_tag="GCM10010348_34390"
     CDS             complement(29..823)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031092.1"
                     /locus_tag="IE283_RS16970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34390"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_193485710.1"
                     /transl_table=11
                     /translation="MTAPATPTAPDRLLAVLAAFDHAHPALSLTDISRRAGLSLTTAHR
                     LVGALTRWGALERDGAGVYHVGLRLWEIAALAPRGLALRQVAWPYLEDLYEATHENVQL
                     AVRDGGEVVYIEWLAARSSVGVHIRVGARWPLHATGVGLALLAHGEPEFQEAYRTGPLA
                     SFTAFTITDPVRLRRVLAEVRRTGAAVSDRQITDDALSVAAPVHGPDGTVTAAVSVVVP
                     HAGAQVPALVPAVRLAARGISRALGWRPNIPRTGEDGPPYSS"
     gene            950..2287
                     /locus_tag="IE283_RS16975"
                     /old_locus_tag="GCM10010348_34400"
     CDS             950..2287
                     /EC_number="3.2.1.86"
                     /GO_function="GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058990.1"
                     /locus_tag="IE283_RS16975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34400"
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="WP_161270325.1"
                     /transl_table=11
                     /translation="MRLTMLGGGGFRVPLVYGALLGDRGEGRVSDVVLHDLDPARLTAV
                     TRVLAEQAAGVPDAPTVTATTDLDEALRGADFVFSAIRVGGLQGRADDERVALAEGVLG
                     QETVGAGGIAYGLRTVPVAVDIARRVARLAPDAWVINFTNPAGLVTEAMSRHLGDRAIG
                     ICDSPVGLGRRVARVLGADPDRAFVDYVGLNHLGWLRGLRVGGRDELPRLLADPALLGS
                     FEEGRLFGAEWLRSLGAVPNEYLHYYYFNRETVRAYQEAGLTRGAFLRDQQARFYDEMR
                     RPDAPALATWDRTRAEREATYMAENRETAGAGEREAEDLSGGYEKVALALMRAVARDER
                     ATLILNVRNRGTLSVLDADAVIEVPCLVDANGAHPMAVDPLPDHATGLVRAVKGVERDV
                     LAAAGTGSRAAAVRAFALHPLVDSVDVARRLVDGYRAVHPGLAYLR"
     gene            complement(2280..3440)
                     /locus_tag="IE283_RS16980"
                     /old_locus_tag="GCM10010348_34410"
     CDS             complement(2280..3440)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031094.1"
                     /locus_tag="IE283_RS16980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34410"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_193485711.1"
                     /transl_table=11
                     /translation="MASPVRVWLNRTYAENVFFMDQLRRNPADRAVEIHATHGDPDSPV
                     LAAADTAEPEPEGLSPAGYVEYALAQCARRGIDVFVPRLHQSAIVAHRAEFEALGTALL
                     APPPEAVAVFRDKVIAYEAVRAIGVPVPPWWRVRTADELVLAVEELEAGGHRACFKPAS
                     GAGGVGFRMVTRDPFSLTHLNGFPSPSVPLPLVVEALRAAEEPVDWLVMPRLEQPEVSV
                     DCLTGPDNRVRLAVGRTKNGRRRGFTLHEQWLTPARRIAETFGLHHLSNVQFRMYGDRP
                     VLMDVNSRPAGGLHQLALCGVNVPWAAVRLALGDDPGELEPPFLGQDYAVVAGPRPLRP
                     VTLPHQRADLPAATTPAPAPAPAAAAAPAPAERAAAPASSAPVGLT"
     misc_feature    complement(3679..3695)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.41"
                     /tool="antismash"
     misc_feature    3695..3710
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(3696..3709)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.47"
                     /tool="antismash"
     gene            3723..4610
                     /locus_tag="IE283_RS16985"
                     /old_locus_tag="GCM10010348_34420"
     CDS             3723..4610
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031095.1"
                     /locus_tag="IE283_RS16985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34420"
                     /product="metallophosphoesterase"
                     /protein_id="WP_011031095.1"
                     /transl_table=11
                     /translation="MTTRAGAPGKLWAISDLHVGYEENRALVERTRPESDDDWLLVAGD
                     VAETVADIRWALGILADRFRRVVWAPGNHELWTHPKDAVDLRGVARYEHLVEMCRELGV
                     TTPEDPYPVWEGAGGPAVVAPLFLLYDYSFLPAGCATKAEGLEYAQGTGVVCSDEYLLH
                     PDPYPSREDWCRARVAETERRLAAIPADLPTIPVNHYPLHRHPTDVLWYPEFAMWCGTS
                     LTADWHRRFRVETMVYGHLHIPRTTWHEGVRFEEVSVGYPREWRKRPGPPGQLRRILPS
                     TRASAAPSHQEVTR"
     gene            4607..5287
                     /locus_tag="IE283_RS16990"
                     /old_locus_tag="GCM10010348_34430"
     CDS             4607..5287
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (103-167). E-value: 6.8e-22. Score:
                     69.8. Matches aSDomain:
                     nrpspksdomains_IE283_RS16990_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031096.1"
                     /locus_tag="IE283_RS16990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34430"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_011031096.1"
                     /transl_table=11
                     /translation="MIEELLPGTVVAVEAFGQDDAGHLPLYPEEEELVARAVAKRRREF
                     TVVRSCARRAMEKLGVPAQPVLTGERGAPRWPEGIAGSMTHCDGYGAAALVRLTDLASL
                     GIDAEPDGPLPDGVLESIALPAEVALLRRLGGARPGVHWDRLLFSAKESVYKAWYPLTG
                     QWLDFTEADIEIRVDPADPRRGTLHAALLVPGPTVDGRRLSRFDGRWSARDGLVTTAVT
                     VPRT"
     aSDomain        4916..5107
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE283_RS16990_ACPS.1"
                     /evalue="6.80E-22"
                     /label="IE283_RS16990_ACPS.1"
                     /locus_tag="IE283_RS16990"
                     /protein_end="167"
                     /protein_start="103"
                     /score="69.8"
                     /tool="antismash"
                     /translation="LGIDAEPDGPLPDGVLESIALPAEVALLRRLGGARPGVHWDRLLF
                     SAKESVYKAWYPLTGQWLD"
     gene            complement(5306..5542)
                     /locus_tag="IE283_RS16995"
                     /old_locus_tag="GCM10010348_34440"
     CDS             complement(5306..5542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972321.1"
                     /locus_tag="IE283_RS16995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34440"
                     /product="hypothetical protein"
                     /protein_id="WP_003972321.1"
                     /transl_table=11
                     /translation="MTTAVLTDRERTAVQAYLRLLHTVRAGFDTGTGPGDSPRPPVVPP
                     SVLAEAEQALRAAGLTGNEEAFFRLLRDWCPPT"
     gene            complement(5638..6294)
                     /locus_tag="IE283_RS17000"
                     /old_locus_tag="GCM10010348_34450"
     CDS             complement(5638..6294)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004980713.1"
                     /locus_tag="IE283_RS17000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34450"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_003972320.1"
                     /transl_table=11
                     /translation="MTGGFEGPGAKPTTTLAAVVARVGALADRLDVPHAEVFDVGRLSA
                     ASGVPESVVGALLGGRPTGGADVQTRFVQRLDLLRRTRLKPNGRKYTQQEIADGAGMSR
                     QQAGALINGDRRPTMEHCDAIQRFFRVHAGFLTAEDPEALAGALQRTEQELLQQLADRE
                     RQAAAPADDPLERLLQDHGVRGIAWRAAQLPTDQHRDKVAEWLDMLLESVKRPES"
     misc_feature    6323..6338
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    complement(6323..6340)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.4"
                     /tool="antismash"
     gene            6527..7186
                     /locus_tag="IE283_RS17005"
                     /old_locus_tag="GCM10010348_34460"
     CDS             6527..7186
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387305.1"
                     /locus_tag="IE283_RS17005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34460"
                     /product="hypothetical protein"
                     /protein_id="WP_016327825.1"
                     /transl_table=11
                     /translation="MAFQAGGQRPAPRPAPATPEAQAYLQDYTALLEAVPFPSLVVDHR
                     WDVVLANGAFRTLFQGAGPHPTAMPDDNFLRFVLFHPDAATVLGEHESSWCLPMLAHFA
                     ATLERYGHDPGLQAVRRDIAQDPIMEAAYRQGLPHWIRAVGARAVEHDGAVRPLHHPDP
                     RRGTTECRVVVETPASLQELGYTRLTLVLREPRRAAHRAPRARHTPAHLRVVPAAE"
     gene            complement(<7207..>7505)
                     /locus_tag="IE283_RS39790"
                     /old_locus_tag="GCM10010348_34470"
                     /pseudo=""
     CDS             complement(<7207..7505)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122244.1"
                     /locus_tag="IE283_RS39790"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="GCM10010348_34470"
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVELLLKQAALSRERRGELVAEALAPVGLADAAGAHPWQSSGGMQ
                     QRVAIARARAYEPEVLLMTEPFTAVDAQTRAGLGDLTSTRPSTWANG"
     gene            complement(7591..8532)
                     /locus_tag="IE283_RS17015"
                     /old_locus_tag="GCM10010348_34480"
     CDS             complement(7591..8532)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972317.1"
                     /locus_tag="IE283_RS17015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34480"
                     /product="PDR/VanB family oxidoreductase"
                     /protein_id="WP_193485712.1"
                     /transl_table=11
                     /translation="MTRYEAELVVGRRETAADGVLVLTLRHPWDEPLPVWEPGAHVDVV
                     LGPGLERQYSLCGDPGDRAVWRVAVLREKAGRGGSAYVHEELRAGDKVRVRGPRNNFRL
                     ERAPRYRFVAGGIGITPVLPMLAAAEEAGAEWSLLYGGRTRAGMAFTKELERYGDRVRI
                     VPEDESGLLDLASVLDDVAPGTLVYCCGPGGLLDAVEARCPAGSLRVERFRPKEADVQA
                     PAGPEFEVVLARSGRTVAVPPGTSVLDAVRETGVEVLYSCTEGTCGTCETEVVEGEPDH
                     RDSVLTEEERAAGETMLICVSRCRGRRLVLDL"
     gene            complement(8529..8699)
                     /locus_tag="IE283_RS17020"
                     /old_locus_tag="GCM10010348_34490"
     CDS             complement(8529..8699)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972316.1"
                     /locus_tag="IE283_RS17020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34490"
                     /product="hypothetical protein"
                     /protein_id="WP_193485714.1"
                     /transl_table=11
                     /translation="MSGRTGEIYRIAWLPGTDVLHGTCHCGAEHTAEDPVAMWDWMLAH
                     PRGHDLPGGGS"
     gene            complement(8696..9775)
                     /locus_tag="IE283_RS17025"
                     /old_locus_tag="GCM10010348_34500"
     CDS             complement(8696..9775)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031099.1"
                     /locus_tag="IE283_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34500"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_093457420.1"
                     /transl_table=11
                     /translation="MPHMTAFARNQWYVAAYSHEVGRELLGRTVLGEPLVLYRAEEDGG
                     PVVLHDRCVHRRYPLSEAPTRLDGDRIVCGYHGFTYDTTGTCVYVPGQKRVPRTARVAS
                     YPVAERDSLVWVWIGDPALADPEAVPRARHLDAPGWVTVRGMEPIDADYGLLVDNLLDL
                     SHETYLHGGHIGTPEVAETPITTEVDEGAGIVRVSRHMDDAECPPFYARSTGIVGRIDR
                     WQDIEYHAPCLYVLHSRVAPTGTVPAPDGGDPEGFHTEITYAITPSGDGKVYDFWAVSR
                     DWATDDAEVTEFLYKSNRTVVMQDVDALNLLQRTLGGEPAGYQELSINIDTGGLAARRI
                     LARLVEEGEGAGTGPRVAR"
     misc_feature    9892..9909
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.66"
                     /tool="antismash"
     misc_feature    complement(9957..9969)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            10001..12697
                     /gene="lanKC"
                     /locus_tag="IE283_RS17030"
                     /old_locus_tag="GCM10010348_34510"
     CDS             10001..12697
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972314.1"
                     /locus_tag="IE283_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34510"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_162495285.1"
                     /sec_met_domain="micKC (E-value: 7.8e-239, bitscore: 789.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 8.4e-11, bitscore: 36.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.5e-06, bitscore:
                     19.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGYAVYCDADPYFYDAPHRTADRTGAARSRYAAASSPVPEGWQ
                     RHESGDWLALRPADADLPAQGWKIHVSACLDNAESVLDRVWRHCVDGGTAFKFVPSRYL
                     LHQRNAKYADRAGSGKFVTVYPADEAEFERLVGELSELLAGEPGPHILSDLRIGDGPVH
                     VRYGGFTRRDCYDADGELRPAVSGPDGVLVPDLRGPVFRIPEWVDPPAFLRPHLDARSA
                     VTVTGMPYTVESALHFSNGGGVYLARDTRTGARVVLKEARPHAGLAADGADAVTRLHRE
                     RRALERLSGLACTPEVLDHRTVGEHHFLVLEHIDGKPLNTFFARRHPLIEADPGERRLA
                     EYTDWALDVHARVERAVAEVHARGVVFNDLHLFNIMVRDDDSVALLDFEAAHHVDEAGR
                     QIVANPGFVAPPDRRGVAVDRYALACLRIALFLPLTSLLAVDRYKAAHLAEVVAEQFPV
                     DRAFLDAAVEEITRVDGSTRVDGSTRADETTRLDGTTRVHGAPDAARRPAGPVAPVRPD
                     DWPRSRDSMAAAIRASATPSRTDRLFPGDIAQFATAGGGLAFAHGAAGVLYALAESGAG
                     RDEDGEQWLLERTKRPPSGMPLGFHDGLAGLAWTLERLGHRDRALDLAELLLDQPLDHL
                     GPDLHGGTAGLGLALESLAATTGQAALHSAALHCAELAADGLPGGSVPADRVSRGRARA
                     GLLYGGAGRALLFLRLFERTRDSALLDLARDALRQDLARCVRGAGGALQVDEGWRTMPY
                     LGAGSVGIGMVLDDYLAHRADEEFARAANEIVAAAQAMFYAQPGLYRGVAGMVLHLGRT
                     TATAPGTGPRAVRRQLDALSWHAMSYRDRLAFPGEQMMRLSMDLSTGTAGCLLAVASVL
                     GDAPAGLPFLPPPRRSGGPLTRPHQEP"
     gene            12735..12863
                     /locus_tag="IE283_RS17035"
                     /old_locus_tag="GCM10010348_34520"
     CDS             12735..12863
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="IE283_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34520"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_003972313.1"
                     /transl_table=11
                     /translation="MNLFDLQSMETPKEEAMGDVETGSRASLLLCGDSSLSITTCN"
     CDS_motif       12735..12797
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNLFDLQSMETPKEEAMGDVE"
                     /locus_tag="IE283_RS17035_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12798..12863
                     /prepeptide="core"
                     /locus_tag="IE283_RS17035_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="32.20"
                     /molecular_weight="1955.2"
                     /monoisotopic_mass="1954.0"
                     /core_sequence="TGSRASLLLCGDSSLSITTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNLFDLQSMETPKEEAMGDVE"
                     /leader_location="[12734:12797](+)"
                     /alternative_weights="1973.2"
                     /alternative_weights="1991.2"
                     /alternative_weights="2009.2"
                     /alternative_weights="2027.3"
                     /alternative_weights="2045.3"
                     /alternative_weights="2063.3"
     gene            12899..14881
                     /locus_tag="IE283_RS17040"
                     /old_locus_tag="GCM10010348_34530"
     CDS             12899..14881
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972312.1"
                     /locus_tag="IE283_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34530"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_193485715.1"
                     /transl_table=11
                     /translation="MSPAAGAPGSGPGRRRLPALDVRRFSPVRKSRPVPPRAPGRALEV
                     LVLLCSVAAAVAAVAQPLALGRTLDLLLRDGDAGWWLPLSAALLLGELLLDSATSLFTG
                     RCNATWTASVRTRALRGLLRTAPEHARPYPPGDIGTRLTLNAADAGGAPAARAALAASL
                     ITPLGALVALALVDVWVALCVLAGLPALALLLRSFARDTGATVAAYQRTQSLIASRLLE
                     ALEGADTIGAAGTGERERARVLAPLAELAAQGRHMWALHGRALGRSGVLVPLLTLAATA
                     VGGLRLAAGELSVGDLLAVGRYAQLTAGVGAAASLLGAIVRAREARRRTRELERMPATA
                     YGTRRLPPNGPGELRLCGVRVLRGGREVLRADGVRVPGGSTVAVVGRSGAGKSVLAAVA
                     GRLIDPDEGHVLLDGVRLDRLTHEALRTEVAYAFERPVLGEDTIAEAVADGARRSSRER
                     VRQAARAAGADGFVRRLPHGYDTPLPRAPLSGGEHQRLGLARAFAHAGRLLVLDDATSS
                     LDTATEHEVDLALRRSVRPGTRLVVAHRPSVADRADLVLWLEDGQVRAVGTHRELWHTA
                     GYREVFGAGAGAGAGAGAGAGAGADAGAGADAGPGPGSAPGPCADAGPGPGPGSGSGPG
                     SGAATAVGGSGPGPVRRPEPEEARP"
     gene            14878..16704
                     /locus_tag="IE283_RS17045"
                     /old_locus_tag="GCM10010348_34540"
     CDS             14878..16704
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972311.1"
                     /locus_tag="IE283_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34540"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_193485716.1"
                     /transl_table=11
                     /translation="MTSTEAGALRRLAPPARRFLAHRKGVLIRLALWSLAESGQAFLVG
                     HAVARSVDEGFLAGDPRRGLLWLGVALVAVLSGARVVRGVFAQLAGVTEPLRDGLVRHA
                     VDRSMARAAPGGPGRTDRAAVSRLTNQVEIARDSFAGLVLTLRSFVFTAAGALLGLLSL
                     HPALLVVVLPPLAAGLALFLVTLRPMAAAQRRALAADEALGEHAASARAALRDLAACGT
                     GPGAERHGADLVADAAAAARTLAGWAAVRTAALGVAGHLPVLALLVAVEWLRGHGVSVG
                     ALLGAFTYLVQSLLPALHTLMTALGAAGSRLLVVLDRILGPEPEPEPEPEPEPEPELGS
                     GLEPEPEPASEPESGPSTASAPAAAFAVHTAAAPAVELRSVTLSYGVRAEPVLDALDLR
                     VAPGEHLAVVGPSGIGKSTLTRLVAGTLAPSRGEVRVAGRVVTGRPAAELAALRVLVPQ
                     DAYVFSGTVGDNLAYLRTDPCPAELDAAVEAFGLAPLVERLGGLDATVRPAELSPGERQ
                     LVALVRAYLSPAPLLLLDEATCHLDPASEARAEKALAGRSGTLVVVAHRLSSAVRADRT
                     LVLDGIRAQSGTHAELLGRSPLYRDLTGHWNS"
     gene            complement(16709..17317)
                     /gene="ramR"
                     /locus_tag="IE283_RS17050"
                     /old_locus_tag="GCM10010348_34550"
     CDS             complement(16709..17317)
                     /codon_start=1
                     /gene="ramR"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031103.1"
                     /locus_tag="IE283_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34550"
                     /product="two-component system response regulator RamR"
                     /protein_id="WP_003972310.1"
                     /transl_table=11
                     /translation="MGEMVRIAVVHDEKLLRSALVQLLRSDDTLDVSSHCLDADGPELS
                     AALPADVCVVDGECLTGPQDAGAGRLRARYGDRLVVLATAKRPGVLRRAFDGGALGLVD
                     KNAPAHRLITAVHTVARGERFLDETLTVALLKGAEMPLTTRELGVLTLASQGAPIAEIA
                     ARLHLSRGTVRNYMATAVRKVGARNRVDAIRIVQSAGWT"
     gene            17846..18724
                     /locus_tag="IE283_RS17055"
                     /old_locus_tag="GCM10010348_34560"
     CDS             17846..18724
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031104.1"
                     /locus_tag="IE283_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_34560"
                     /product="DUF4132 domain-containing protein"
                     /protein_id="WP_193485717.1"
                     /transl_table=11
                     /translation="MGWLAAGDTYEVALVEGRVVARSASAKSPAEGRRERTLPAEIRER
                     PEVVELQRFAEWLDRHAAECVAQVDNWMVSSLPVPTALLAQVWPDEAWQTALRDIVVVG
                     EGPDEVGFLRDADESQGLRVVNLDGETVRLTSRTVTMPHPVLLPDLEELRTFAAESGVV
                     QGVEQILRATWPAPGDSDGGDTDVVTEFAGAEYRSWFHLSARATSLGYRISGSRVVDRI
                     RDAGRVFTASVGMSDPYTEEKAWTGGLSWSHGDGYRSLPLHEVGPVAYSEGMRMAAALH
                     AGRTVPTDGAE"
     misc_feature    complement(19765..19780)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.31"
                     /tool="antismash"
     misc_feature    complement(20928..20941)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.82"
                     /tool="antismash"
     misc_feature    22517..22526
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 ggctcctggg gcacgggccg tcccagtatc aggaggagta cgggggcccg tcctcaccgg
       61 tgcgagggat attcgggcgc cagcccaggg cccgtgagat gccgcgggcc gccagccgga
      121 ccgccgggac cagcgccggc acctgcgcgc cggcgtgcgg cacgacgacc gacacggcag
      181 cggtcacggt gccgtccggg ccgtgcaccg gggcggccac cgagagggcg tcgtcggtga
      241 tctgccggtc gctcaccgcc gctccggtgc gccgcacctc ggccagcacc cggcgcaggc
      301 gtaccgggtc ggtgatcgtg aacgcggtga aggaggcgag cggcccggtg cggtacgcct
      361 cctggaactc cggttcgccg tgggcgagca gggcgagccc gaccccggtg gcgtgcagcg
      421 gccagcgggc gcccacgcgg atgtgcacgc cgaccgacga acgcgccgcc agccactcga
      481 tgtagacgac ctcgccgccg tcccgcaccg ccagctgcac gttctcgtgg gtcgcctcgt
      541 acaggtcctc caggtacggc cacgccacct gccgcagcgc gagaccgcgc ggggcgagcg
      601 cggcgatctc ccacaaccgc aggcccacgt ggtagacgcc cgcaccgtcc cgctccagcg
      661 caccccaccg ggtcagggcg cccaccagcc ggtgtgccgt ggtcaggctc agcccggccc
      721 ggcggctgat gtccgtcagg gacagggccg ggtgcgcgtg gtcgaacgcg gcgagcacgg
      781 cgagcagccg gtcgggggcg gtgggggtgg caggggcggt caccgggccg agggtagggg
      841 cccgcccgcc ccctggacag aggaaagggg aggtgcacgc gcggaggcac cggccgtgcc
      901 atgatcggcg ccggacggaa gtgcggccgg gcgacggaag ggtgccaacg tgaggctgac
      961 gatgctgggc ggcggcgggt tccgcgtacc gctcgtgtac ggggcgctcc tcggagaccg
     1021 cggcgaggga cgcgtgagcg acgtcgtcct gcacgacctg gacccggccc ggctgacggc
     1081 ggtgacccgg gtactggccg aacaggcggc cggggtgccc gacgcgccga cggtgaccgc
     1141 gacgaccgac ctcgacgagg cgctgcgcgg cgccgacttc gtgttctccg cgatccgcgt
     1201 aggcggcctc cagggacgcg ccgacgacga acgggtggcg ctcgccgagg gcgtcctcgg
     1261 ccaggagacg gtcggcgcgg gcggcatcgc ctacgggctg cggaccgtcc cggtcgccgt
     1321 cgacatcgcc cgccgggtgg cccggctggc accggacgcc tgggtcatca acttcaccaa
     1381 cccggcgggc ctggtcaccg aggccatgtc ccggcacctc ggcgaccggg ccatcggcat
     1441 ctgcgactcg ccggtcggcc tcggccgccg cgtcgcccgc gtgctgggcg ccgacccgga
     1501 ccgcgccttc gtcgactacg tcggcctcaa ccacctcggc tggctgcgcg gcctgcgcgt
     1561 cggtggacgc gacgagctgc cgcggctgct ggccgacccg gcgctgctcg gttccttcga
     1621 ggagggccgg ctcttcggcg ccgagtggct gcgctccctc ggcgccgtcc ccaacgagta
     1681 cctgcactac tactacttca accgggagac cgtccgcgcc taccaggagg ccggcctcac
     1741 ccggggcgcg ttcctgcgcg accagcaggc ccgcttctac gacgagatgc gccgccccga
     1801 cgccccggcc ctcgccacct gggaccgcac ccgcgccgaa cgcgaggcca cgtacatggc
     1861 cgagaaccgc gagacggcgg gcgcgggcga acgcgaggcc gaggacctgt ccggcggcta
     1921 cgagaaggtg gcgctggcgc tgatgcgcgc cgtcgcccgt gacgaacgcg ccaccctgat
     1981 cctcaacgtc cgcaaccgcg gcacgctctc cgtcctcgac gccgacgcgg tgatcgaggt
     2041 cccctgcctg gtcgacgcga acggcgccca cccgatggcg gtcgatccgc tgccggacca
     2101 cgccaccggc ctggtccgcg cggtcaaggg cgtcgagcgc gacgtactgg ccgcggccgg
     2161 gaccggctcc cgcgcggccg cggtccgtgc cttcgccctg caccccctcg tcgactcggt
     2221 cgacgtcgcc cgccgcctcg tcgacggcta ccgggcggtg cacccgggac tggcctacct
     2281 caggtgagcc ccacgggggc ggacgacgcc ggtgccgccg ccctctctgc cggtgccggt
     2341 gccgctgccg ctgccggtgc gggggccggt gccggtgtcg tcgcggccgg gaggtccgcg
     2401 cgctggtgcg gcaaggtcac cgggcgcagc ggacgcggtc ccgccaccac cgcgtagtcc
     2461 tgacccagga acggcggctc cagctcgccc gggtcgtcgc cgagggccag ccggaccgcc
     2521 gcccacggca cgttgacccc gcacagcgcc aactggtgca gtccgcccgc cgggcggctg
     2581 ttgacgtcca tcaggacggg ccggtcgccg tacatccgga actgcacgtt ggacaggtgg
     2641 tgcagcccga acgtctcggc gatccgccgt gccggtgtca gccactgctc gtgcagggtg
     2701 aacccgcggc ggcggccgtt cttggtgcgg cccacggcga ggcggacccg gttgtccggc
     2761 ccggtgaggc agtccaccga gacctccggc tgctccaggc gcggcatcac cagccagtcc
     2821 acgggctcct cggccgcccg cagcgcctcg acgaccaggg gcagcggcac ggacgggctc
     2881 gggaagccgt tgaggtgggt cagggagaag gggtcccggg tgaccatccg gaagcccacg
     2941 ccgcccgcgc cggaggccgg cttgaagcac gcccggtggc cgcccgcctc cagttcctcc
     3001 accgcgagga ccagttcgtc ggccgtgcgc acccgccacc acggcggcac cggcacgccg
     3061 atcgcgcgga ccgcctcgta ggcgatcacc ttgtcccgga agacggccac cgcctcgggc
     3121 ggcggcgcga gcagcgccgt acccagcgcc tcgaactcgg cgcggtgggc cacgatcgcg
     3181 gactggtgca gccggggcac gaacacgtcg atgccgcgcc gcgcgcactg ggccagggcg
     3241 tactcgacgt aaccggccgg ggagagcccc tcgggctccg gttccgcggt gtccgcggcg
     3301 gccagcacgg gggagtccgg gtcaccgtgc gtggcatgga tctcgacggc ccggtcggcg
     3361 ggatttctcc gcagctgatc catgaagaag acgttctccg cgtacgtgcg gttgagccag
     3421 acgcgtacgg gagaagccat gcaagccgcc ttccagggtt cgcgggcagg gcgaagcggg
     3481 ccgtgcccgg ccaggggttt ggagggacac cgagccgctc tgcgcgaaag gagagtcgtg
     3541 gcggggtgtt ggggcgatca taggggtacg cgcggccccc agcgcaacga gcgtcacacg
     3601 gatgccccgg cccggccgtg cggcggcccc cgggacagtc gcacggccgg gccgggtcgc
     3661 cttgtgaccc gcccggggat gtgatctcgt ggcgtcgaac gtgtgtctgg aaggggtggg
     3721 ggatgacgac gagggccggg gctccgggga agctgtgggc catcagcgat ctgcacgtcg
     3781 gatacgagga gaaccgggcc ctggtcgagc ggacgcgccc cgagtccgac gacgactggc
     3841 tgctggtggc cggcgacgtg gcggagaccg tcgccgacat ccgctgggcc ctcggcatcc
     3901 tcgcggaccg cttccgccgg gtcgtctggg cccccggcaa ccacgaactg tggacacatc
     3961 ccaaggacgc ggtcgacctg cgcggcgtcg cccgctacga gcacctcgtc gagatgtgcc
     4021 gggaactggg cgtgaccacc cccgaggacc cgtacccggt gtgggagggc gcgggcggcc
     4081 cggcggtcgt cgcgccgctc ttcctgctct acgactactc gttcctgccc gcggggtgtg
     4141 cgaccaaggc cgagggactg gagtacgccc agggcaccgg cgtcgtgtgc agcgacgagt
     4201 acctgctgca ccccgacccc tatcccagcc gcgaggactg gtgccgggcg cgggtcgccg
     4261 agaccgagcg ccggctcgcc gcgatccccg cggacctgcc cacgatcccg gtcaaccact
     4321 acccgctgca ccggcacccc accgacgtcc tgtggtaccc ggagttcgcc atgtggtgcg
     4381 gcacctcgct gaccgccgac tggcaccgca ggttccgggt ggagaccatg gtctacgggc
     4441 atctgcacat cccgcgcacc acctggcacg agggggtccg cttcgaggag gtctcggtgg
     4501 gctatccccg cgagtggcgc aagcggcccg ggccgccggg gcaactgcgc cgcatcctgc
     4561 cgtcgacgcg ggcgtccgcg gcaccgtcgc accaggaggt gacccgttga tcgaggaact
     4621 gctgcccggc acggtcgtcg ccgtggaggc cttcggccag gacgacgccg gtcacctgcc
     4681 cctgtatccg gaggaggagg aactcgtcgc gcgggcggtc gccaagcggc gccgtgagtt
     4741 caccgtggtg cggtcctgcg cccgccgggc catggagaag ctcggcgtgc cggcacagcc
     4801 cgtgctgacc ggcgagcgcg gggctccgcg ctggcccgag gggatcgccg gcagcatgac
     4861 ccactgcgac ggctacggcg ccgccgccct ggtccgcctg accgacctgg cctcgctggg
     4921 catcgacgcc gaacccgacg ggccgctccc ggacggcgtc ctggagagca tcgccctgcc
     4981 cgccgaggtg gccctgctgc ggcggctggg cggcgcgcgg cccggcgtcc actgggaccg
     5041 gttgctgttc agcgccaagg agtcggtcta caaggcgtgg taccccctca ccgggcagtg
     5101 gctggacttc accgaggcgg acatcgagat ccgcgtggac ccggccgacc cgcgccgcgg
     5161 caccctgcac gccgccctcc tggtgccggg accgaccgtg gacggcaggc gcctgagccg
     5221 cttcgacggc cgctggagcg cccgggacgg cctggtcacc acggcggtca cggtcccgcg
     5281 cacctgaact gcgcccgccc gccggtcagg tgggcgggca ccagtcccgc agcagccgga
     5341 agaacgcctc ctcgttcccc gtcagtcccg cggcccgcag cgcctgctcc gcctcggcca
     5401 gcacggaggg cgggacgacg ggcgggcggg gagagtcgcc ggggcccgtc ccggtgtcga
     5461 aaccggcccg cacggtgtgc aggagccgca gataggcctg gacggcggtg cgttcgcggt
     5521 cggtcagtac ggcggtggtc atcggtcggc tctccccaca acgacgtcag cggtcacgcg
     5581 cccccgcacg gcggcggcac cctcccagct tgccgtccac cactgacaat cccggcctca
     5641 cgactcgggc cgcttgacgc tttccaggag catgtccagc cactcggcga ccttgtcgcg
     5701 gtgctggtcg gtgggcagtt gcgcggcccg ccaggcgatg ccgcgcacgc cgtggtcctg
     5761 gagcagccgc tccaacgggt cgtcggcggg ggccgccgcc tgccgctccc ggtcggcgag
     5821 ctgctggagc agctcctgct cggtgcgctg gagggcgccc gcgagcgcct cggggtcctc
     5881 ggcggtgagg aatccggcgt gcacccggaa gaagcgctgg atggcgtcgc agtgctccat
     5941 ggtggggcgc cggtcgccgt tgatgagcgc accggcctgc tgccgcgaca tcccggcgcc
     6001 gtcggctatc tcctgctggg tgtacttgcg gccgttcggc ttcagccggg tgcggcgcag
     6061 caggtccagg cgctgcacga acctggtctg cacgtcggcc ccgcccgtcg gccggccccc
     6121 gagcagggcc ccgacgacgg actcggggac gccggaggcg gcggacagcc ggcccacgtc
     6181 gaagacctcg gcgtgcggta cgtcgagccg gtccgcgagg gcgccgaccc gggcgacgac
     6241 ggcggccagc gtggtggtcg gcttggcgcc cggaccttcg aagccacccg tcaccgacag
     6301 ctctcctacg tctctcacag gcctcacagg cttctcacaa gcggttgccg tgaacttccc
     6361 ggagagtagc ctgccgctcg aactcacatc caggcatcgc cacaactgtg gcctatttca
     6421 gccgtcaaca ggcacgaaat gccacgatag ttgacacgcc tcgcgtcggg gcgacaggat
     6481 gcggacgccg cgagaaggcc gcataggcaa gaggggtgac ctcccgatgg catttcaggc
     6541 aggtgggcag cggccggcgc cgcggcccgc ccccgcgacc cccgaggccc aggcctatct
     6601 ccaggactac accgccctcc tggaggccgt ccccttcccc tctctcgtcg tcgaccaccg
     6661 ctgggacgtg gtgctggcca acggcgcctt ccggacactc ttccagggcg ccggaccgca
     6721 cccgacggcc atgccggacg acaacttcct ccggttcgtc ctcttccacc cggacgccgc
     6781 cacggtcctc ggcgagcacg agtcgagctg gtgcctgccc atgctggcgc acttcgccgc
     6841 caccctggag cggtacggcc acgatcccgg actccaggcc gtccgccggg acatcgccca
     6901 ggacccgatc atggaagctg cctaccgcca gggcctgccg cactggatcc gcgccgtcgg
     6961 agcgcgggcc gtcgaacacg acggtgccgt gcggccgctg caccacccgg acccgcgccg
     7021 cggcaccacc gagtgccggg tcgtggtcga aacgcccgcg tcgctccagg agctgggcta
     7081 cacgcggttg acgctggtcc tcagggagcc gcgccgcgcc gcccaccggg cgccacgtgc
     7141 ccgccacaca cccgcccacc tgagagtcgt ccccgccgcc gagtgacggg tggtcagtgc
     7201 ggggggtggg gcggcggaca gtacgatcac ccgttcgccc aggtggacgg cctcgtcgat
     7261 gtcaggtccc cgaggccggc gcgggtctgc gcgtcgaccg ccgtgaaggg ttcggtcatc
     7321 agcagcacct cgggttcgta cgcccgcgcc cgcgcgatgg ccacccgctg ctgcatgccc
     7381 ccggacgact gccacgggtg ggccccggcg gcgtccgcga gcccgaccgg cgcgagcgcc
     7441 tccgcgacca gctccccgcg ccgctccctg ctcaacgccg cctgcttcag cagaagttcg
     7501 acgttccggc aggtccgggg cgcggccctg gtccacgccc gtgccgagat gggccgttga
     7561 ggtttcaacc gagcaggtgc cgccgtcgag tcacaggtcc agcacgagcc gccggccccg
     7621 gcaccgtgac acgcagatga gcatggtctc cccggcggcc cgctcctcct cggtgagcac
     7681 cgagtcccgg tggtccggct cgccctcgac gacctccgtc tcacaggtcc cgcaggtccc
     7741 ctccgtgcag gagtagagca cctcgacgcc cgtctcgcgg accgcgtcca ggaccgatgt
     7801 gccgggcggg acggcgaccg tacggccact gcgcgcgagg acgacctcga actccggccc
     7861 cgccggggcc tgcacgtcgg cctccttcgg gcggaaccgc tccacacgca ggctcccggc
     7921 cgggcagcgc gcctcgaccg cgtccagcag cccgccgggc ccgcagcagt agacgagggt
     7981 gcccggggcc acgtcgtcca gcacggacgc gaggtcgagc agccccgact cgtcctccgg
     8041 gacgatcctc acccggtcgc cgtaccgctc cagctccttc gtgaacgcca tcccggcccg
     8101 ggtccgcccg ccgtacagca ggctccactc ggcgcccgcc tcctcggcgg cggccagcat
     8161 cggcaggacc ggggtgatgc cgataccgcc ggcgacgaag cggtagcggg gtgcccgctc
     8221 cagccggaag ttgttgcgcg ggccgcgcac ccggaccttg tccccggccc gcaactcttc
     8281 gtggacgtag gccgagccgc cccgcccggc cttctcgcgc agtaccgcga cccgccacac
     8341 cgcccggtcg cccgggtcgc cgcacagcga gtactgacgc tccagaccgg ggccgaggac
     8401 gacgtcgacg tgggcgccgg gctcccagac cgggagcggt tcgtcccacg gatggcgcag
     8461 ggtgagcacc agcacgccgt cggccgcggt ctcccggcgg ccgacgacga gttcggcttc
     8521 gtagcgggtc atgaaccgcc cccgggcagg tcgtgtcctc gcgggtgcgc gagcatccag
     8581 tcccacatcg cgaccgggtc ctcggcggtg tgctcggcgc cgcagtggca ggtgccgtgc
     8641 agcacgtcgg tgccggggag ccaggcgatg cggtagatct cgccggtacg cccgctcacc
     8701 gggccacccg cggcccggtc ccggcgccct cgccctcctc gaccaggcgg gccaggatgc
     8761 ggcgggcggc caggcccccg gtgtcgatgt tgatgctcag ctcctggtag ccggcgggct
     8821 cgccgccgag cgtgcgctgg agcaggttga gcgcatcgac gtcctgcatg acgaccgtgc
     8881 ggttgctctt gtacaggaac tcggtgacct cggcgtcgtc cgtcgcccag tcccgggaga
     8941 ccgcccagaa gtcgtacacc ttcccgtcgc cggacggcgt gatggcgtag gtgatctcgg
     9001 tgtggaagcc ctccggatca ccgccgtcgg gcgcgggcac ggtgccggtc ggcgcgaccc
     9061 tgctgtgcag cacgtacagg cagggcgcgt ggtactcgat gtcctgccag cggtcgatgc
     9121 gcccgacgat gcccgtcgac ctggcgtaga acggcgggca ttcggcgtcg tccatgtgcc
     9181 ggctcacccg gacgatgccc gcgccctcgt cgacctcggt ggtgatcggc gtctcggcga
     9241 cctcgggcgt gccgatgtga ccgccgtgca gataggtctc gtgggagagg tcgagcaggt
     9301 tgtcgaccag cagcccgtag tccgcgtcga tcggctccat gccccggacc gtgacccagc
     9361 ccggcgcgtc caggtgccgg gcccgcggca ccgcctcggg gtcggccagc gccgggtcgc
     9421 cgatccacac ccacaccagg gagtcccgct cggccaccgg gtaggaggcg acgcgggcgg
     9481 tgcgcgggac gcgcttctgg cccggcacgt acacgcaggt gccggtcgtg tcgtaggtga
     9541 acccgtggta cccgcacacg atccggtccc cgtccagccg ggtgggcgcc tccgagagcg
     9601 gatagcggcg gtgcacacag cggtcgtgca ggaccaccgg gccgccgtcc tcctcggcgc
     9661 ggtagagcac gagcggttcg ccgaggaccg tgcgccccag caactcgcgc cccacctcgt
     9721 gactgtaggc ggcgacgtac cactggttcc tggcgaaggc ggtcatgtgc ggcatgcgcg
     9781 gctcccgtcg tcctcgacgt cgtgtggtca caccatcgcc acgccgtccc gccccggcaa
     9841 cagcccttcc gccacgcgga attctcccgc tccgggagtc ccgccgccgc gaagttactt
     9901 gtgcgttccg cacctcggag tggtgacagc cgcaactgtc cgaggcggta cgccgcgtga
     9961 cagcgtcgtc tccgtcagcc accggtggga gggagcaggc gtgaacaagg gctacgccgt
    10021 gtactgcgac gcggacccgt acttctacga cgccccgcac cgcaccgccg accggaccgg
    10081 ggccgcgcgc tcccggtacg ccgccgcctc ctcgccggta ccggaggggt ggcagcgcca
    10141 cgagagcggg gattggctcg cgctgcgtcc ggccgacgcc gacctgcccg cccaggggtg
    10201 gaagatccat gtctccgcct gcctcgacaa cgcggagtcc gtgctcgacc gggtgtggcg
    10261 gcactgcgtc gacggcggta cggccttcaa gttcgtgccc agccgctatc tgctgcacca
    10321 gcgcaacgcc aagtacgcgg accgggccgg cagcggcaag ttcgtcaccg tgtacccggc
    10381 ggacgaggcg gagttcgaac ggctcgtggg agagctgtcc gaactgctgg ccggcgagcc
    10441 cggaccgcac atcctgagcg acctgcggat cggcgacggc cccgtgcacg tccgctacgg
    10501 cggcttcacc cggcgcgact gctacgacgc ggacggggaa ctgcggccgg ccgtgtcagg
    10561 acccgacggt gtgctggtgc ccgacctgcg cggtccggtc ttccgcatcc cggagtgggt
    10621 cgacccgccc gccttcctgc gcccgcacct cgacgcccgc tccgcggtga ccgtgaccgg
    10681 catgccgtac accgtcgagt cggcgctgca cttctccaac ggcggcggcg tctacctcgc
    10741 ccgcgacacc cgcaccggtg cgcgggtcgt cctcaaggag gcccgtccgc acgccgggct
    10801 ggcggccgac ggcgccgacg ccgtgacccg gctgcaccgt gaacgccggg cgctggagcg
    10861 gctgtcgggg ctcgcctgca cgccggaggt gctcgaccac cgcacggtcg gggagcacca
    10921 cttcctcgtc ctggagcaca tcgacggcaa gccgctcaac acgttcttcg cccgccggca
    10981 cccgctcatc gaggccgacc cgggcgagcg gagactggcc gagtacaccg actgggccct
    11041 cgacgtccac gcgcgggtgg aacgcgccgt cgcggaggtc cacgcccggg gtgtggtctt
    11101 caacgacctg cacctgttca acatcatggt ccgggacgac gacagcgtcg ccctgctgga
    11161 cttcgaggcc gcccaccacg tcgacgaggc gggacggcag atcgtggcga acccggggtt
    11221 cgtggcgcct cccgaccggc gcggggtggc cgtggaccgg tacgcgctgg cgtgtctgcg
    11281 gatcgcgctg ttcctcccgc tcaccagtct gctggccgtc gaccggtaca aggcggcaca
    11341 cctcgcggag gtggtggcgg agcagttccc ggtggaccgg gcgttcctgg acgcggcggt
    11401 cgaggagatc acgcgcgtcg acgggagcac ccgcgtcgac gggagcacgc gcgccgacga
    11461 gaccacgcgc ctcgacggga ccacgcgcgt ccatggagcc ccggacgcgg cgcggcggcc
    11521 cgccggtccg gtggcgcccg tccggccgga cgactggccg cgcagccggg actccatggc
    11581 ggcggcgatc cgcgcctccg cgacgccctc ccgcacggac cgcctcttcc ccggtgacat
    11641 cgcgcagttc gccacggcgg gcggcgggct ggccttcgcc cacggtgcgg cgggggtgct
    11701 gtacgccctg gccgagagcg gggccggacg ggacgaagac ggcgagcagt ggctgctgga
    11761 gcggaccaaa cgaccgccgt cgggcatgcc gctcggtttc cacgacgggc tcgccggact
    11821 cgcctggacc ctggagcgcc tcggccaccg cgaccgcgcc ctcgacctcg ccgaactcct
    11881 cctcgaccag ccgctcgacc acctgggccc ggacctgcac ggcggcaccg ccggtctcgg
    11941 cctggccctg gagtcgctgg ccgccaccac cggtcaggcc gcgctccact cggcggcgct
    12001 gcactgcgcc gaactggccg ccgacgggtt gccgggcggg agcgtgccgg ccgaccgcgt
    12061 cagccgcggc cgcgcccgag ccgggctgct gtacggcggc gcggggcggg ccctgctctt
    12121 cctccggctc ttcgaacgca cccgggactc cgccctcctc gacctcgccc gcgacgcgct
    12181 gcgccaggac ctcgcccgct gcgtccgcgg cgcgggcggc gcgctgcagg tcgacgaggg
    12241 ctggcgcacc atgccctacc tgggtgccgg cagtgtgggc atcggcatgg tgctggacga
    12301 ctacctggcg caccgggcgg acgaggagtt cgcacgggcc gcgaacgaga tcgtggccgc
    12361 ggcccaggcg atgttctacg cccagcccgg gctctaccgg ggcgtggccg gaatggtcct
    12421 gcacctgggc cgcaccacgg ccacggcgcc cggtacggga ccgcgggccg tacggcgcca
    12481 actggacgcc ctgtcctggc acgccatgtc ctaccgcgac cggctcgcct tccccggcga
    12541 gcagatgatg cgcctgtcca tggacctctc caccggaacg gccggatgcc tgctcgccgt
    12601 cgcctccgtc ctcggcgacg cgcccgccgg actgccgttc ctgccgccgc cgcgccgaag
    12661 cggcggcccc ctgactcggc cccaccagga gccgtgagaa aagcacaccc cttgccgaac
    12721 gaaaggaatg cgtcatgaac ctgttcgacc tgcagtcgat ggagaccccc aaggaagagg
    12781 ccatggggga cgtcgagacc ggcagccgcg cgagcctcct gctctgcggc gacagcagcc
    12841 tgagcatcac cacctgtaac tgacacaggg gttgacggcc acggcgacgt ggtgagtcat
    12901 gtcgccggcc gcgggcgccc cgggttccgg cccggggcgc cgacgcctgc cggcgctcga
    12961 cgtacggagg ttctcgccgg tgcgaaagag caggcccgtg ccgccgcggg cgccggggcg
    13021 cgccctggaa gtcctggtcc tgctgtgctc ggtcgcggcg gccgtggcgg cggtggccca
    13081 gcccctggcc ctcggccgca ccctggatct gctcctgcgc gacggcgacg ccggatggtg
    13141 gctcccgctg agcgccgcac tgctcctggg tgaactgctg ctggacagcg cgacctcgct
    13201 gttcaccggc cgctgcaacg ccacctggac ggcgtccgtc cgcacccgcg ccctgcgtgg
    13261 actgctgcgc accgcccccg agcacgcgcg gccgtacccg ccgggcgaca tcgggacccg
    13321 cctgaccctc aacgccgccg acgcgggcgg cgctccggcg gcccgcgcgg cgctggccgc
    13381 ctcactgatc accccgctgg gcgccctggt ggcgctggcg ctcgtcgacg tgtgggtggc
    13441 gctctgcgtg ctggccggtc tgcccgccct ggcgctgctg ctgcgttcct tcgcccgcga
    13501 caccggcgcc acggtcgccg cctaccagcg cacccagtcc ctgatcgcct cccggctgct
    13561 ggaagccctg gagggagcgg acacgatcgg tgccgcggga accggcgaac gggagcgggc
    13621 ccgtgtcctg gcaccgctgg cggaactggc cgcccagggc cggcacatgt gggcgctgca
    13681 cggacgggcg ctcggccgga gcggtgtcct ggtcccgctg ctgacgctgg ccgccaccgc
    13741 cgtcggcggg ctgcggctgg cggccggcga actgagcgtg ggggacctgc tcgccgtcgg
    13801 ccggtacgcg cagctcacgg ccggcgtcgg cgcggcggcg tccctcctcg gggcgatcgt
    13861 ccgggcccgc gaggcacggc gccggacccg ggagctggaa cggatgcccg cgacggcgta
    13921 cggcacgcgg cggctgcctc caaacggtcc gggagagctg cgactgtgcg gggtgcgcgt
    13981 gctgcgcggc ggcagggagg tgctgcgcgc cgacggcgtg cgggtaccgg gcggcagcac
    14041 ggtcgcggtg gtcggccgca gtggggcggg caagtccgtc ctggcggccg tcgcgggacg
    14101 gctgatcgac cccgacgagg ggcacgtcct gctggacggc gtccggctcg accgcttgac
    14161 gcacgaggcg ctgcgcaccg aggtggcata cgccttcgaa cggcccgtac tgggagagga
    14221 cacgatcgcg gaggcggtcg ccgacggggc acggcggtcg tcgcgtgagc gggtacgcca
    14281 agccgcccgg gcggcgggcg ccgacggctt cgtacgccgg ttgccgcacg gctacgacac
    14341 cccgctgccg cgggcaccac tctcgggcgg ggagcaccag cggctcggac tggcgcgggc
    14401 cttcgcgcac gccgggcggc tgctggtgct ggacgacgcc acgtccagtc tggacaccgc
    14461 cacggagcac gaggtggacc tggcgctgcg tcgctcggtg cggccgggga ccaggctcgt
    14521 ggtggcgcac cgcccgtcgg tcgcggaccg ggccgacctg gtgctctggc tggaggacgg
    14581 gcaggtgcgc gccgtcggaa cccatcgcga gctgtggcac acggcggggt accgggaggt
    14641 cttcggcgca ggagcgggag cgggagcggg agcaggagcc ggagcaggag ccggagcgga
    14701 tgccggtgcc ggtgctgatg ccggtcccgg tcccggttcc gctcccggtc cctgtgctga
    14761 tgccggtccc ggtcccggtc ccggttccgg ttccggtccc ggttccggtg ccgccaccgc
    14821 cgtcggcggc agtggcccgg ggcccgtacg ccgtccggag cccgaagagg cgcgcccgtg
    14881 acgtccacgg aggccggggc gctgcgccgc ctcgcaccgc cggcccgccg cttcctcgcc
    14941 caccgcaagg gggtgctgat acggctcgcg ctctggtcgc tggccgagtc ggggcaggcc
    15001 ttcctggtcg gccacgcggt cgcgcgctcc gtcgacgagg ggttcctcgc cggtgatccg
    15061 cgccggggac tgctgtggct cggggtcgcg ctggtcgccg tactgtccgg cgcccgggtc
    15121 gtccggggcg tgttcgcgca gctcgccggg gtgacggagc cgctgcgcga cggcctggtg
    15181 cggcatgcgg tcgaccggtc catggcccgg gcggcaccgg gcggccccgg ccggacggac
    15241 cgcgcggccg tctcgcggct gacgaaccag gtggagatcg cccgggacag cttcgccggt
    15301 ctcgtcctca ccctgcggtc cttcgtcttc accgccgccg gcgcactgct cggcctgctg
    15361 tccctgcatc cggccctgct cgtggtggtg ctgcccccgc tggcggccgg gctcgcgctg
    15421 ttcctggtca cgctgcggcc catggcggcc gcccagcgcc gggccctggc ggccgacgag
    15481 gcgttgggcg agcacgcggc gagcgcgcgt gcggcgttgc gggacctcgc cgcctgcggg
    15541 accgggcccg gggcggagcg gcacggcgcg gacctggtcg ccgacgccgc cgcggcggcc
    15601 cggacgctgg ccggatgggc ggcggtgcgc acggcggcgc tcggcgtcgc gggccacctg
    15661 cccgtgctcg cgctgctggt ggcggtggag tggctgcgcg ggcacggggt gagcgtgggg
    15721 gcgctgctgg gcgcgttcac ctacctcgtc cagtccctgc tgcccgccct gcacaccctg
    15781 atgaccgcac tgggcgcggc cgggtcccgg ctgctggtcg tcctcgaccg gatcctcggc
    15841 ccggagccgg agccggagcc ggagccggag ccggagccgg agccggagtt ggggtcgggg
    15901 ctggagccag agccagagcc agcgtcagag cccgagtcgg ggccgagcac cgcgagcgca
    15961 ccggcggcgg cattcgcggt gcacaccgcc gcggccccgg cggtggagct gcggtccgtc
    16021 accctgtcct acggcgtccg ggccgagccc gtgctcgacg cgctcgacct gcgcgtcgcg
    16081 ccgggtgaac acctcgccgt cgtgggaccg agcggcatcg ggaagtccac cctcacccgc
    16141 ctcgtcgcgg gaacgctcgc gccgagccgt ggcgaggtac gcgtggccgg ccgcgtggtg
    16201 acggggcgcc ccgccgccga gctcgccgca ctccgggtgc tggtcccgca ggacgcctac
    16261 gtgttctccg gcaccgtcgg cgacaacctc gcctacctgc ggacggaccc gtgcccggcc
    16321 gaactcgacg ccgcggtcga ggcgttcggt ctcgcgcctc tggtcgagcg gctgggcggg
    16381 ctggacgcca cggtgcgccc cgccgagctc tcgccggggg agcggcaact ggtcgcgctg
    16441 gtccgcgcgt acctgtcgcc cgcccccctg ctgctgctcg acgaggccac ctgccatctc
    16501 gatccggcct ccgaggcccg cgcggagaag gccctcgccg ggcggtccgg gaccctggtc
    16561 gtggtggcgc accggctgtc ctcggccgtc cgtgcggacc ggaccctggt gctggacggc
    16621 atacgggcgc agagcggaac gcacgccgaa ctgctgggcc gttcgcctct ctaccgggac
    16681 ctgacgggac actggaactc gtgacgggtc aggtccagcc ggcgctctgc acgatgcgga
    16741 tcgcgtcgac gcggttgcgg gcacccacct tccggaccgc cgtggccatg tagttgcgga
    16801 ccgtcccccg ggacaggtgc aggcgcgccg cgatctcggc gatcggcgcc ccctgggaag
    16861 ccagggtcag cacgcccagt tccctcgtgg tcagcggcat ctccgcaccc ttcagcaggg
    16921 ccacggtgag cgtctcgtcc aggaagcgtt cgccccgggc gaccgtgtgc acggcggtga
    16981 tcagccggtg ggccggggcg ttcttgtcga ccagcccgag ggcgcccccg tcgaacgccc
    17041 ggcgcagcac tcccggccgc ttggcggtcg ccaggaccac gagccggtcc ccgtaccggg
    17101 cccgcaggcg tccggctccc gcgtcttgcg gccccgtcag gcactctccg tccacgacac
    17161 agacgtcggc gggcaatgcc gcactcagct ccggaccgtc ggcgtcgagg cagtgcgagg
    17221 acacgtccag cgtgtcgtcg gatctgagca gttgcaccag tgccgaccgc agcagcttct
    17281 cgtcgtgcac cacggcaata cgaaccatct cccccacccc ttgtcagcgg cggccccgtt
    17341 cgggccaccg ggctccgcgc gcccccgcgc cctcgggcca tgtgccccca tccgggacgg
    17401 cggaacacga cacgtacgca cgtgcgaacc gcatcggagg caattcgccg tcgtcagggc
    17461 cttgtcgggg gacggccgag acgggtgcgg cagcgaagaa gggcggataa cacaccaatc
    17521 cgcggacggc ttcggcccgt gcgtgaaccg acgggagtcc gccgtcttcg cgtcgcggcc
    17581 cctggcgtcc tggccagggc gggttccgct gcccggggcc ggccgcgccc gccgcccggg
    17641 cccgaccggc cggcggtccg ggcgacaccg ggcccggccg aaaagcgccg ctgtccaatg
    17701 tggcgcgaaa ggcaccgcgc gatcggcccc cgtggctgtc ggtgggtgcc cctagtcttt
    17761 ggccaacgcc acagcggagc gtgccgattc aggggccccg tgtgctgtgc cgtgtgttcc
    17821 tagtagtggg agaggcgaag agctgatggg ttggctggca gcgggcgaca cgtacgaagt
    17881 cgccctggtg gagggccggg tggtggcgcg gtccgcgtcc gcgaagtccc cggcggaggg
    17941 caggcgggaa cgaacgctgc ccgcggagat acgggagcgc cccgaggtgg tcgaacttca
    18001 gcgcttcgcc gagtggctgg accggcacgc cgccgaatgc gtggcgcagg tcgacaactg
    18061 gatggtgtcc tcgctcccgg tgcccaccgc gctgctcgcg caggtctggc ccgacgaggc
    18121 gtggcagacg gccctgcggg acatcgtcgt ggtcggcgag ggccccgacg aggtcggctt
    18181 cctgcgcgac gcggacgagt cgcagggact gcgggtggtg aacctggacg gggagaccgt
    18241 ccgcctgacc tcccgcacgg tgaccatgcc gcacccggtc ctcctccccg acctggagga
    18301 actgcgtacc ttcgccgccg agtcgggcgt ggtgcagggc gtggagcaga tcctccgggc
    18361 cacctggccg gcgcccgggg actccgacgg cggcgacacc gacgtggtca ccgagttcgc
    18421 gggtgccgag taccgctcgt ggttccacct gtccgcccgc gccacgtccc tcggttaccg
    18481 gatctccggg agccgcgtcg tcgaccgcat ccgggacgcc ggtcgcgtct tcaccgcctc
    18541 cgtcggcatg agcgacccct atacggagga gaaggcctgg accggcggcc tgagctggag
    18601 ccacggggac gggtaccgga gtcttccgct gcacgaggtc ggccccgtcg cctattccga
    18661 gggcatgcgc atggcggcgg ccctgcacgc cggccgcacc gtgcccacgg acggcgccga
    18721 gtgaacgcca ccgcgatacg cacacccacg aaaggcacgc gatcatgagc gatggcacga
    18781 cacggcacgg ggcggcggaa gaggtggcgg agctgctgcg ctccggagcc gtgttgccgc
    18841 ccggcaccgc cgggggcggc gaccgcgccg tgcccgtgtt cacccgggcg taccggcatc
    18901 cggggctgga cgaccggatc gtcgtacgtc tgacgcccgc cgacccgtcc ggcacggaac
    18961 ccgccgcggg agacccggcg ggcggggacg gtggcgggtt cctcgggctg ctgcccgtgg
    19021 gcgagccggt cgaggtcggc gtcggacagc accgggccat gggctttccc gagtgggtgc
    19081 tggtccgcca ccccaccgac ggccacctcg cgatgtccct ggtcgaggag atgaacaagg
    19141 tcgccaggac ggtgcgctcc cgggcgaaga gggcccgcgc cacctacgag tcgatcggcg
    19201 cccgcctcgc gggttccgtg ccgcacttcc tgcccacctt ctacgaggag gccggccggg
    19261 tgttcctggc cgccggcgag aaggcctacg cctcgcagat gttcgtcaac gcgcgcaagg
    19321 ccgagacggc ccatgccctg ccgttcgacg aggcccgcat ggacgcggtg ttcctggagt
    19381 tcgccctcgc cgacgccatg ccgaccaagg tgctctccag ttacgccaag ggactctcgt
    19441 cccgggtgcc ggccgccacc gcctaccggc acctgcgcgg gctcttcgtc cggctcgccg
    19501 cgcacggcgt ggccccgtcg agccccggcg cgggtgacct gcgaaagctg gcgaaggccg
    19561 tcgcgggcag gaacgctctc gccgaggaga tggcgtacct gcgcgaggtg ctgccgctgc
    19621 ccggcacccg caaggcacca cccggctggt ggaaggccca ccgggccgcc ctgctggaac
    19681 tgacccggcg cgaacccgcc gcccgcggca ccctgctcgg actgctcccc tcggagtggg
    19741 agcacgagga gctggggcag tggctcgacc tgctggacaa gaccggcgcc accgagggac
    19801 tgtgcgacgc cacgctgccc gccgaggccc ggtcacccga cggcaccgtc ggctggaccc
    19861 gcaggttcct cgccctgtgc cgcacccacg agcggtacct cgcaccgtcc gagctgtacc
    19921 ccctcgtgga ccgcatggcc ggtgccctgc gcgccgaact gaaggacgag aacgccacgt
    19981 tgcgaccccc ggtcggcgac gtcgaccttc tcgaccagct cctcgccctg gacgtcccgg
    20041 tcggcgaccc cgaggcccgc ccgtggctca acctccagga ctgggcggcc cgcgacggac
    20101 ggcgcgacct cctcgctctg gcggccgaca cccgcttccg agaagtcttc cggagcggct
    20161 gccccaccta cgagcgcgag ggcatcgaca agcgcaccgt ggcccggctg gccgagtcgc
    20221 cgggcggccg cccgatgctc gccgagtggg tggccggggt cagccgcggc tacctcacct
    20281 gcggactggg tgacttcgct ctcaacagcg gcccgttcca gacgctgaac tggctgccgg
    20341 gcgagatcct ggcgaccgcc gagcaggagg tgcgggacgc gctgggcacc ggcatggcgc
    20401 ccgtgctggg ccgcgccctg cggaacggcc tgctcgacga actgggctgg cccgcctggg
    20461 acgaggcgat cggctcgtcc gcgtccccgg agcaggcccg ggcgacacag gtggcggagg
    20521 cctggccgca cctcgtcgtc cttcagggca cgcacgcccg ggtgctcggc gcgcagggca
    20581 cggtcctcag ccaccagctc cgcctcccgg acgagcgggg cccgggcagc cccgacgtcc
    20641 ggtacgtgga cggcgcactg ctcgtctcct ggtacgtgtc cgccacatcc acctcgtacg
    20701 gctactggta ccaccccgac acgggcgtct cgccgaccac ggaactcacc ggcgacgtcc
    20761 gttcctgcta ctcctgccac gcggacggca gcggcgggac gaacggcatg ccgcccgcct
    20821 cactcccgct ctccgggggc ggcaggacca ccggccacgg cgtgctgcga cccggggaca
    20881 cccacgttcc gtggcggcgc cgggtgatcg gcgacggcac ctcgcactgg gtctggatcg
    20941 acgactggtc ccgcgagaag aacagcacct ggcacgccta cgagccggcc gacgacacgg
    21001 cgggggagcg cggcggcccg gactggttcg ccgaagggct gcgcgccgca ccggagggca
    21061 gcactctcgg cgcctgctgg ctgctgcccg ccccgtccgc cgaaccgggc ccggtgtgcg
    21121 ccccggtgga cgggctgctc ggctggcggg tgatcatcgg gcccgacggc tcgcggcacg
    21181 gacaggacct ggccggccac tcggtcgtcg taccgcggcg cgtgggcggg agcccggaga
    21241 acgcgctggt cttcccaggc accgaccggg ccgtcaccgt gatgcgatgg tcgagcgacc
    21301 tccaactgcg ggactccgac caggcggtgc tggcccactt caagcgtgat cagacagccg
    21361 gtcccttctc cgcgggcacc cccctgctgc cgcccctgcg ctactggcac ctgctccggc
    21421 cccgcgaccc gcagggctcc gcggcgctcc gccgggtcgg cgacgacgtc gcggcggagc
    21481 tgctggcggc ggccgtcgcc gagacgaccg gagagggggc ggcggaccgg gacgcggtgc
    21541 tcggccccgt ccgcacgctc ttcccggagg tcggcgacga ggcgctgctc cggggcatca
    21601 ccggcgtggc gcgctacgcc gccgagcagc agcgcgtcct ggacgggctg ctcgcccggc
    21661 tggactcggc ggtccggggc gtcgtcccgg aggagccgcg gcccgcactc ggcgaccgcc
    21721 tgctcgcctc cgcgctgaac ggcgtcggcc tgaccgaacg cgacgcacgc tggtactacg
    21781 acttccagca cagcctcttc gagcttccgc agctcctcgc ccggtcgatg aagggcctgg
    21841 ccgaaccggc tcccgcgggc atctttcacc tgtcgctcgc caagcaggag ccgttggagc
    21901 acctcaacgg gctggccctg cccgagttgc ccgccgtact ggccctccgg gcggcctcgg
    21961 aagccaccga ggaggaacac cggcaggccc tggacacctt cctcggcgaa ctggacgcgc
    22021 acgggctgac ggaactggac cccggccact ggcgccgggt gcacctggcc ttcgaccccg
    22081 acaccttcga cggaccgggc gacacgcacg gctacaggag agggacggtg ctcaacctgg
    22141 agggcggcgc gttcctcgtc ttccccgacg actggtacca gttcgtccgc gagtacggac
    22201 cccacgaggt caagggcaag cactacgggg cggcctacca cgacccgtcc ggccgcttcg
    22261 agacgccggc cccctacacg ccggtgtccg aggagccgtt cgtcccggag ccgacccgga
    22321 cgcccggctg ggtcgccgcc ttccgtgccg aactggccga gcgcggcccg gtgccctggc
    22381 gccccgaggc cgccgaggag ttcgcccggc tcaccggcgt caccccgacc acggcccggc
    22441 tggtgctcgc cggcatgccg cagaccgacg acaagcgcgc gaacgtgccc tccgcgaccc
    22501 tgaaggtcat cggggtgaag gcggccgacg cccgtgtgtc caaggacgaa ctgagatcgc
    22561 tcgacagcgc cgccctgcgg gccgtggtgg cggcactgct gcccaccgaa ccgtcccggc
    22621 tctggacgca cggccccgac accgcccgcg cggccgaggt ctggaacgag cggctgggca
    22681 gacgcacccc gctgccc
//
