LOCUS       NZ_BMVQ01000004        22181 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces anthocyanicus strain JCM 4739 sequence04, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVQ01000004
VERSION     NZ_BMVQ01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces anthocyanicus
  ORGANISM  Streptomyces anthocyanicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces violaceoruber group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 618389)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:14:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,934
            CDSs (total)                      :: 7,858
            Genes (coding)                    :: 7,681
            CDSs (with protein)               :: 7,681
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 177
            CDSs (without protein)            :: 177
            Pseudo Genes (ambiguous residues) :: 0 of 177
            Pseudo Genes (frameshifted)       :: 73 of 177
            Pseudo Genes (incomplete)         :: 130 of 177
            Pseudo Genes (internal stop)      :: 16 of 177
            Pseudo Genes (multiple problems)  :: 37 of 177
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:48:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 216138
            Orig. end                         :: 238319
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVQ01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22181
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22181
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22181
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12181](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12181)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    40..54
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    1165..1179
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.83"
                     /tool="antismash"
     misc_feature    1199..1213
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     misc_feature    complement(1924..1942)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.14"
                     /tool="antismash"
     misc_feature    complement(1925..1941)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            complement(2176..3501)
                     /locus_tag="IE283_RS13785"
                     /old_locus_tag="GCM10010348_27930"
     CDS             complement(2176..3501)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445382.1"
                     /locus_tag="IE283_RS13785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_27930"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_016327597.1"
                     /transl_table=11
                     /translation="MDELGARAAALVARYPRHARLRRVGTSRAGSPLLLLSVGHGSRQV
                     LVVGGPHANEPVGGATALRLAERAVADPRLTEGADATWNLLLCVDPDGLRRNEGWLTGP
                     YTLGRYARNFFRPGFLEQPEWLPDGPDRATLPETRTLLALQDELRPFLQCSLHGVDVGG
                     GFVELTHELPGLAQRISHTAARLGIPRELGAYDTLYWPDLGPAVYRIPPPRRGDLTAAI
                     TEAAVDSTWCHPRRHGTVTAVVEAPMWGVAAVADDSPPVDRDGVLRTVSRTLRHDTRRL
                     RRVLARLRPHLAAVPEAAHLLAPVDDYLLVCPRLADEWDPDTDDRTDRSLPPMNTSHLV
                     ALRLAGRRLSLRTAGLLHQLVTRTGGDPAGVLAELDRLVDEGCADYRDGCGAHWIPVGR
                     QVEYQTRVVLAAFELAGRRAAAGARSGEPGRGSEAAVPMHRD"
     misc_feature    3621..3636
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.43"
                     /tool="antismash"
     gene            complement(3727..4278)
                     /locus_tag="IE283_RS13790"
                     /old_locus_tag="GCM10010348_27940"
     CDS             complement(3727..4278)
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="IE283_RS13790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_27940"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_093457227.1"
                     /transl_table=11
                     /translation="MTSSFEFPTYPARLSDAERDKALSVLRDGVAMGRLSHDTFIRRME
                     LALAARRLEELAVLTADLPTENRLSRLVFGTVEAVSGFGVRLGRAWRAERLPKLLLPHP
                     GAGHPLRIGRDPASGLRLSHETVSRVHAELSRQGGMWVLRDLGSTNGTTVNGRRVIGAA
                     VVREGDQIGFGGMSFRLAAN"
     misc_feature    4307..4321
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.42"
                     /tool="antismash"
     misc_feature    complement(4310..4325)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            4456..6201
                     /gene="treZ"
                     /locus_tag="IE283_RS13795"
                     /old_locus_tag="GCM10010348_27950"
     CDS             4456..6201
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034231.1"
                     /locus_tag="IE283_RS13795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_27950"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_011030636.1"
                     /sec_met_domain="CBM_48 (E-value: 1.2e-05, bitscore: 20.6,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 2.5e-12, bitscore:
                     42.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQAGRVTLRCDGATRALERDPERPGWWCGEAPARDGSR
                     YGFAVDDGPVLPDPRSRRQPDGPDGLSAVVDHGRYAWRTPWAGRPLPGGVLYELHVGTY
                     TPEGTLDAAADRLEHLVRLGVTHVELMPLCPFPGRHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDRAHDLGLGVVLDVVHNHLGPSGNHLPAFGPYFTDTHHTPWGVAVNLDAPGSDEVR
                     AYLVDSALAWLRDYRLDGLRLDAVHALADTRACHFLEQLSTAVDGLAADLERPLFLIAE
                     SDLNDPRIITPRAEGGLGVHAQWNDDFHHALHAALTGESQGYYADFARDPLAALAKTLI
                     RGYFHDGTYSSFRGRSHGRALDRGRVAAHRLTGYSQTHDQVGNRAQGDRLASLVSPGLA
                     ACAATLTLTAPFTPMLFMGEEWAAGTPWQFFTDHTDPQLAQAVRQGRRREFAAHGWREE
                     DVPDPQDPATRERSCLDWSEPEREPHARVLDWYRRLIALRAEQPDLTDPDLADTRVAYD
                     GTGRWLAFRRGDIRVAVNLGTEPAAIPLGNRPARVLAAWEPVEGPGANGILRVPGESSV
                     VLVQE"
     gene            complement(6212..7156)
                     /locus_tag="IE283_RS13800"
                     /old_locus_tag="GCM10010348_27960"
     CDS             complement(6212..7156)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972843.1"
                     /locus_tag="IE283_RS13800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_27960"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_193485428.1"
                     /sec_met_domain="APH (E-value: 2.1e-18, bitscore: 62.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRRLVRSLLGGSTEPDVRPVAEGVAPDTWWVGTR
                     HVLRLAPDRETAVRGRRELRLRELVRPYLPVALPASVAHGEWAPGLAYTLDAKVAGGSG
                     EDHDVSALGEADLAALLTGLREVPVRQAETLGVPRAAPRSLEALRQSAERAVRRLAAAD
                     EFDTARPERLTREAAAQLGVQPGAAVLVHHGLTGGHLVVSADGRVRGVLGWSDAVLGDP
                     AEDIAGLALSVGSPAAVRAATLAGYGARPCLRGLWLARCDAVIHLAEALDGHCGGPPPA
                     TVPLLRTRLRRAWEPILLERVTELRNDGRDDTA"
     gene            complement(7213..8343)
                     /locus_tag="IE283_RS13805"
                     /old_locus_tag="GCM10010348_27970"
     CDS             complement(7213..8343)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="IE283_RS13805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_27970"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_003972844.1"
                     /transl_table=11
                     /translation="MTGSSPAASFTADDYRARMERAARAAADAGLAGLLVAPGPDLVWL
                     TGYAPTADTERLTLLVLAPDRDPVLVVPTLEAPDAAKAAGAPALTLRDWTDGKDPYAAT
                     AALLDGSGRFGISDNAWAMHLLALQRTLPDTSYASLTEALPMLRAVKDAAELELLAAAG
                     AAADAAFEEIRRVRFGGRRESEVAADLADLLRRFGHSQVDFTIVASGPNGANPHHEVGD
                     RVIEDGDMIVLDFGGLKDGYGSDTSRTVHVGAPTDEERRVHDLVREAQEAGFCAVRPGA
                     ACQDVDRAARAVIAGAGYGEYFIHRTGHGIGVTTHEPPYMIEGEERPLVPGMCFSVEPG
                     VYLPGRFGVRIEDIVTVTEDGGRRLNDTTREMVVVE"
     misc_feature    8466..8483
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.61"
                     /tool="antismash"
     gene            8528..9283
                     /locus_tag="IE283_RS13810"
                     /old_locus_tag="GCM10010348_27980"
     CDS             8528..9283
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327595.1"
                     /locus_tag="IE283_RS13810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_27980"
                     /product="metallophosphoesterase"
                     /protein_id="WP_173668774.1"
                     /sec_met_domain="Metallophos_2 (E-value: 3.7e-09, bitscore:
                     31.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLAHISDLHLDGSPRATERAERVRERLWRLPGRVDALLVTGDI
                     ADHGTEAEYEEAARVLGLRDGSAPFPVLTCPGNHDSRAPYRKALLGRPAADGPANEVHV
                     FDGGAVLMCDSSIPGSDEGELDGETYDWIEASLDGLDHGLPALLAFHHPPTPVHHPLPD
                     SYRLRHPERLAALLERRPGIAGLITGHAHSPAATVFAGRPLVVGPGVTWTLRLPWEGEQ
                     VADRDAPVGLAFHVLDDAGRLTSHFRTVT"
     gene            complement(9276..9917)
                     /locus_tag="IE283_RS13815"
                     /old_locus_tag="GCM10010348_27990"
     CDS             complement(9276..9917)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327594.1"
                     /locus_tag="IE283_RS13815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_27990"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_193485430.1"
                     /transl_table=11
                     /translation="MEQTALRPKPMPGRDPGPGTEPDGARHPHTGRRRRRRLTTLLLGV
                     LAAAVLLLTGVGLGTVGATVIGMSKLAELRQRAAAQGPGGAGGAGGAGEQGATGTATGT
                     RGAPAHPSAGPSAGRSPSPAPAGATLGVEAVDDEKPGARVVGVHVPGPGYAAGLVRGDV
                     LLAVGTTRVDSATDLAHAVASAGPGKEVKLTVRHRSGGYQQLTAVPGVVT"
     gene            complement(10001..12181)
                     /gene="cyc2"
                     /locus_tag="IE283_RS13820"
                     /old_locus_tag="GCM10010348_28000"
     CDS             complement(10001..12181)
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030632.1"
                     /locus_tag="IE283_RS13820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28000"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_189283656.1"
                     /sec_met_domain="T1TS (E-value: 6.2e-77, bitscore: 254.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQQPFQLPHFYLPHPARLNPHLDEARAHSTTWAREMGMLEGSGV
                     WEQSDLEAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLEKYKRSQDRLAGKA
                     HLDRLPLFMPLDDAAGMPEPRNPVEAGLADLWTRTVPAMSADWRRRFAVATEHLLNESM
                     WELSNINEGRVANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAGTRPLRVLMETFS
                     DAVHLRNDLFSYQREVEDEGELSNGVLVLETFFGCTTQEAAELVNDVLTSRLHQFEHTA
                     FTEVPAVALENGLTPPEVAAVGAYTKGLQDWQSGGHEWHMRSSRYMNKGERPLAGWQAL
                     TGPGTSAADVGALLADAVAQRARSYTYVPFQKVGPSVIPDIRMPFPLELSPALDGARRH
                     LSEWCREMGILSEGVWDEDKLESCDLPLCAAGLDPDATQDQLDLASGWLAFGTYGDDYY
                     PLVYGHRRDLAAARLTTTRLSDCMPLDGEPVPPPGNAMERSLIDLWVRTTAGMTPEERR
                     PLKKAVDDMTEAWLWELSNQIQNRVPDPVDYLEMRRATFGSDLTLGLCRAGHGPAVPPE
                     VYRTGPVRSLENAAIDYACLLNDVFSYQKEIEYEGEIHNAVLVVQNFFGVDYPAALGVV
                     QDLMNQRMRQFEHVVAHELPVVYDDFQLSEEARTVMRGYVADLQNWMAGILNWHRNVPR
                     YKAEYLAGRTHGFLPDRIPAPPVPRSSPALTH"
     gene            complement(12331..13548)
                     /locus_tag="IE283_RS13825"
                     /old_locus_tag="GCM10010348_28010"
     CDS             complement(12331..13548)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523405.1"
                     /locus_tag="IE283_RS13825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28010"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_193485432.1"
                     /transl_table=11
                     /translation="MADTPSVTAPVILGDEPGSFPHGVLAERHPAIVRQVRDAFPFGPE
                     RLRALDALLASCADGVVEPLPADADPTGRDRDRWARWGMDAYAGRSWYDVPWLWAESHF
                     YRRLLDAVGYFGPGAWQGVDPFRPAKLAELDAPETDEELAALDGLDELPTEERTRALLH
                     GSLWGNRADLGFRLSDRGAGTEGAVEALVADDSDALWSLLPAPGTGPAERGPATLCLVA
                     DNAGRELVPDLLLVSHLLAEGRVDQAVLHVKPYPYYVSDATPTDVLDALRRLVAAGGAA
                     AAHGERLWTALTDGRVTVRAHPFSCAPLPYADMPDDLREDFAAATVTVLKGDLNYRRLV
                     GDRWWPPTTSFARVTAYFPGPVAALRTLKSDVVTGLDAKTEAALDASGERRWRTSGTHA
                     LIQVRS"
     misc_feature    complement(13858..13873)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            complement(14168..14815)
                     /gene="cprB"
                     /locus_tag="IE283_RS13830"
                     /old_locus_tag="GCM10010348_28030"
     CDS             complement(14168..14815)
                     /codon_start=1
                     /gene="cprB"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030630.1"
                     /locus_tag="IE283_RS13830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28030"
                     /product="transcriptional regulator CprB"
                     /protein_id="WP_011030630.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRATIIGAAADLFDRRGYESTTLSEIVAHAGVTKGA
                     LYFHFAAKEDLAHAILEIQSRTSRRLAKDLDGRGYSSLEALMRLTFGMARLCVQGPVLR
                     AGLRLATAGVPVRPPLPHPFTEWREIATSRLLDAVRQSDVHQDIDVDSVAHTLVCSVVG
                     TRVVGGTLEPAGREPRRLAEMWYILIRGMVPVTRRARYVTLAARLEQETGTA"
     misc_feature    15031..15047
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.22"
                     /tool="antismash"
     gene            15170..16183
                     /locus_tag="IE283_RS13835"
                     /old_locus_tag="GCM10010348_28040"
     CDS             15170..16183
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972851.1"
                     /locus_tag="IE283_RS13835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28040"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_011030629.1"
                     /transl_table=11
                     /translation="MSTAPPPTHSPGPARAAALTAAVCLLVAGCSALGGDEDGSAADAA
                     GGSGGDRMKIVMVTHGGEGDAFWDRVRKGAEAAAAKDGVDLTYAGDADTADQADLVRDA
                     IRDKADGIAVTLAKPQAMKAPVAEAKAAGIPVVGLNSGIDAWRSTGLLEYFGQDESVAG
                     RAVGDKLDDLRAKHALCVIHERGNVALEARCAGVKKTFGGETEMLYVEGTDMKAVGAAV
                     TARLRQDPSIDEVVMNGAAFALTAVEAVDEAGSDAHVATFDLDNDLVAAVKRGDVQFAV
                     DQQPYLQGYLAVDALWLYRTNGNVSGGGVAPVLTGPAFVTRTNADSVAEFAAGGTR"
     gene            16252..18885
                     /locus_tag="IE283_RS13840"
                     /old_locus_tag="GCM10010348_28050"
     CDS             16252..18885
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327592.1"
                     /locus_tag="IE283_RS13840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28050"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_189283653.1"
                     /transl_table=11
                     /translation="MPARKSRKKGARRRLGSIRLSLILLALVPGVTLAAVWGVTTIQMF
                     SEGLRLRAQTQLSRDTGAMGTEATLALQKERSLSAAWLAAPDGDRSELDAQRKKTDAAV
                     AQLVGQSDAIESAPTRVSDRLYSVLGSVGSLEYYRNQVDDPSDITAEQALDQYTSIVDE
                     QIHAFQELSQVDDGDLTSQAGPLVALEHAAELVSQEDARLTLAWPSGRMDEEQWSRFAQ
                     LVHTRRWLVQDQIVPSLTGSAKTQTERILASSEWKSLQDVEDQVLEARSAGRGDRIDLP
                     DARQRWITAFEKISTQYGQLIRQQTDGLLDRSAEEARGLLIKAGVLSAGGLIALLLCIV
                     MSWRITRSLSRRLRGLRLATLSLAEERLPDVVARLERGETVDVESATPPLDYGRDELGQ
                     VAQAFNTAQRTAVHTAVELADTRRGFQKVILGIARQSQNLVNMQLGKLDALEREHTDPE
                     ILKGLYELDSTASQLRRYEENLVIISGEQPRRTWREPVSLVDILRSAVGEVAEYQRVEL
                     HADEEVALAPPAVADVIHLLAELIDNATAYSPAPNPVGVRAALVAKGLAVEIEDRGLGL
                     SEEDYASFNAQLAVAPQFDVVALADDLRLGMFVVARLAHRHGITVTLRPSPYGGTTAIV
                     LIPHDIVVREPAGGADGTGAAANGARAPWVAAPTARDSADPAGPAIDTGSVTGTGTETG
                     QAAPGAAAGRSATASAAAGDPSGDPRPVRPVRSSRPAPAGPAAAGAGSPRGHSGASAHD
                     ASDGRGGLAPLPRRVPQTSLAAELRDEDPGGRRDGSDHAAADAYADFTAERAASSLAGF
                     QRGTLRAHTDDDADEAADPRAAHEADEAAEGVGGADDRATDGHALSSAAHSTPTADRRP
                     PTKDTR"
     gene            18882..19301
                     /locus_tag="IE283_RS13845"
                     /old_locus_tag="GCM10010348_28060"
     CDS             18882..19301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326005.1"
                     /locus_tag="IE283_RS13845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28060"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_003972853.1"
                     /transl_table=11
                     /translation="MTRPSPATHTELDQLLTGLVERVADVNQAVVLSEDGLVVSKSTGF
                     LRDDAERLAATASGLMSLSKGVSMDFRGGPVRQALIEMANSYLILTSAGPGAHLVVLTG
                     PNADVGVVAYQMNMLVKKIGEHLSAAPRATAGPGE"
     gene            19303..19662
                     /locus_tag="IE283_RS13850"
                     /old_locus_tag="GCM10010348_28070"
     CDS             19303..19662
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445342.1"
                     /locus_tag="IE283_RS13850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28070"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_003972854.1"
                     /transl_table=11
                     /translation="MTGGDAAGRLVRPFTLTGGRTRPSRADFTLITTVTAIDPQPSRAA
                     RPQPEHLRILRLCAEPMAVAELAARLDLPVSVVVILLSDLLEAGRITARPPHPVSRATD
                     DLDLLQKVRDGLGRL"
     gene            19649..20260
                     /locus_tag="IE283_RS13855"
                     /old_locus_tag="GCM10010348_28080"
     CDS             19649..20260
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445341.1"
                     /locus_tag="IE283_RS13855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28080"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_016327591.1"
                     /transl_table=11
                     /translation="MAGSERVAETPTASARSTAPEAVKILIAGGFGVGKTTMVGSVSEI
                     APLRTEEPLTAAGLDVDDLAGIEEKRATTVALDFGRITIGRDVVLYLFGTPGQQRFWFM
                     WNDLAIGALGAVVLVDVRRPESSFAAIDFFERRGIPFVVAVNGFHGRHPYPAAEIREAL
                     ALPEHVQVLLCDARERTSSRDVLIALIDQLIDAAAGAAAS"
     gene            complement(20292..21254)
                     /locus_tag="IE283_RS13860"
                     /old_locus_tag="GCM10010348_28090"
     CDS             complement(20292..21254)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972856.1"
                     /locus_tag="IE283_RS13860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28090"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_003972856.1"
                     /transl_table=11
                     /translation="MNFTAKSSRSRTRHTGAAAVALTAAAALLAGCSSDSDGTSDNPLA
                     GDKAEAGTVVVGSNNFAESTLLADIYGEALKAKGLKVTYKHNIGSRETTYGMMKNGSVT
                     VLPEYNGSLLAYLDPKARQKSVEAVNEAAKAKLDKKLTLLESSPAENKDSVSVNAETAK
                     KHGLTAESTLADLKDVAPDLVIGGSPEFQTRQQGLKGLESVYGLKFKSFKALDAGGPLT
                     QSALTKNDVQAADVFTTDPTIIKEKFVVLKDPENLFGHANVTPLVTKDGLNEEGVATLN
                     AVSAKLDTETLLDLDAQVQLDKKDPLDVAKEWLKSAGLV"
     gene            complement(21328..21993)
                     /locus_tag="IE283_RS13865"
                     /old_locus_tag="GCM10010348_28100"
     CDS             complement(21328..21993)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445352.1"
                     /locus_tag="IE283_RS13865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_28100"
                     /product="ABC transporter permease"
                     /protein_id="WP_011030627.1"
                     /transl_table=11
                     /translation="MNVLDFVNAFFSDSAHWHGYDGIPTRLLEHVQYTLMALGLAAAIG
                     LPVGLLTGHTGRGGNAVAFVATAARALPSFGLLVLIAVVVGIGLLPVMVPLVVLAVPPI
                     LVTTYEAVRSVDPSPVDAARGMGMHESGILFRVELPVALPLVLSGLRSAAIQVVSTATI
                     AAYVSLGGIGRYIIDGLYQRDYEKVVGGATLVAVLALVTLALFWAAGRFAVSPGVRRR"
     misc_feature    complement(21959..21974)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     misc_feature    22156..22171
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.27"
                     /tool="antismash"
ORIGIN
        1 tgtcgcgcac cgcgcgggag cacggcctgg gcctggtggt ggacatcgtg cccaaccaca
       61 tggcgatgtc gccgcgtcac aaccacgccc tgtgggaggt gctgcgcgag gggccctcat
      121 cgccctacgc gcggtggttc gacatcgact ggcaggcgca ggacggccgg ctgctgctgc
      181 cggtgctggg cgccccgctc ggcgaggtgc tggacgacct ccgggtcgac ggcgacgtgc
      241 tgcgctacca cgagcacgcc ttcccgctgc gggacggcac cgcggacctg ccgctgccac
      301 ggctgctgga cgcgcagtgg taccgcccgg tgtggtggcg gctggcccgc accgagctga
      361 actaccggcg cttcttcagc atctcggagc tgatcggcgt gcgcgtggag gacccggagg
      421 tgttcgaggc gacgcacggc accgtcctgc ggctgctgca cgagggcgtg atcgacggac
      481 tgcgcgtcga ccatcccgac ggcctcgccg accccgacgc gtacctggaa cggctgcacc
      541 gggcgagcgg cggacggtgg acggtggtgg agaagatcct cgcggacggg gagcggctgc
      601 ccgccgcctg gcccgtcgcg ggcacgaccg gctacgacgc cctgcggcac gtcgacgggc
      661 tgttcacgga ccccgccggc tacggacaac tgctcgaccg gtaccgacgg ttcgccgccc
      721 cgcaggcgga cctgggcggg gactgggcgg cgacggtgcg gcgcgcggcg tacgaggtgc
      781 tcacgcacga gctggccacc gagctggacc ggctgacccg ggtggcgcac cgcctgtgcg
      841 ccgccgcgcc ggacccggcg ctgcgcgacc gggcgccctg ggcgttgcgc acggcgctgg
      901 tggagctgct ggtgcggctg gaggtgtacc ggccgtacac ctcggtggac gcggcggcgg
      961 tcgtcaccga ggaggcggcc gccggggcgc ggcacgcctt cacggtgccc gaggaggccg
     1021 gcgcggtgga cgtcgtacgg ggcctggtgc tggggcggta cggggacgga ccggatcacg
     1081 tggagttccg gacgcggttc gcgcagaccg cgtcggcgct gcgcgccaag tccgtcgagg
     1141 acacggcctt ctaccgctac gtaccgttgc tgtcggccac cgaggtgggc ggggatccgg
     1201 gccgtccggc cgtgtcgccg caggagttcc acgcctactg cgcgcgcgtg cagcgcgact
     1261 ggcccgccac gggcacggtc gtgtcgaccc atgacaccaa gcgcagcgcc gacgtccgcg
     1321 ccgcgctggc ggtgctgacc cagtgccccg cgcggtgggc ggacgtcctg accgaggccg
     1381 ccggggccac cggcacggac gagggtccgc cggacgggca gctggcgtgg gcggcctggc
     1441 agacggtgtt cggtctgggc ccggcggacc gggaacgggt gcgggaggcg ctgctcaagc
     1501 acgtgcgcga ggcggggacg cacaccacct ggacggagca ggacccctcg tacgaggagg
     1561 cggtggcccg gttcgtggcg gcggggccgg gcggcgcgcc gggcgcgcgg gtgaccgccc
     1621 tgcgcgaggc gctggcgccg cacatccggg ccaacgtcct cggcacggcc ctggtccacc
     1681 tgacgatgcc gggcgtaccg gacctctacc agggcaccga gcacgagtac ctggccctgg
     1741 tggacccgga caaccgccgc gcggtggact tccccgcggc cggggacgag ggctgggccg
     1801 ggggccccgg ggcgaaggcg gcggtgacgc gggcggcgct ggcgctgcgg gcccggcggc
     1861 ccggcgtctt cggcgacacg gggacgtacg agccgctgcc cgccgagggc ccggcggcgg
     1921 cacactgcgt ggcgttcgcc aggtcggggc ggaccgtgac cgccgtgacc cggctgtcgc
     1981 tgcggctggc cgaggcgggc ggctggcgcg gcacgacgct gccgctgccg cccggcagat
     2041 gggccgacgc gctggcgccc gggcgggagt tcgcgggcga cgcgcgcgtg gcggaccttt
     2101 tcgcggacac gccggtggcg ctcctggagc gggtggagga ggcgggcaca cggtggaacg
     2161 gcggctgatc gcgggtcagt cgcggtgcat cggcaccgcg gcctcggaac cccggcccgg
     2221 ctcgcccgag cgggcgcccg cggcggcacg ccgtccggcc agttcgaagg cggcgagcac
     2281 gacccgggtc tggtactcca cttggcgccc gaccggtatc cagtgcgccc cgcagccgtc
     2341 gcggtagtcg gcgcagccct cgtcgacgag ccggtccagc tcggccagga cgcccgccgg
     2401 atcgcccccg gtacgggtga ccagctggtg cagcagcccc gcggtacgca gcgacaggcg
     2461 gcgcccggcc agccgcagtg ccacgaggtg ggaggtgttc atcggcggca gtgagcggtc
     2521 ggtccggtcg tcggtgtcgg ggtcccactc gtcggcgagc cgggggcaga ccagcaggta
     2581 gtcgtcgacc ggtgcgagca ggtgcgccgc ctccggcacg gcggcgaggt ggggcctgag
     2641 ccgggcgagg acgcggcgca gccggcgggt gtcgtggcgc agggtgcggc tcacggtgcg
     2701 caggacgccg tcgcggtcga cggggggcga gtcgtccgcc acggccgcca cgccccacat
     2761 gggagcctcg acgaccgcgg tgacggtgcc gtggcgccgc gggtggcacc aggtcgagtc
     2821 gacggcggcc tcggtgatgg cggcggtcag gtcgccgcgg cggggcggcg ggatgcggta
     2881 gacggcgggt ccgaggtcgg gccagtacag ggtgtcgtag gcgccgagtt cgcggggtat
     2941 gccgagccgc gccgcggtgt gggagatgcg ctgggccagg cccggcagct cgtgggtcag
     3001 ctcgacgaag ccgccgccga cgtccacgcc gtgcagggag cactgaagga agggccgcag
     3061 ttcgtcctgg agcgcgagca gggtgcgggt ctcgggcagc gtggcgcggt ccgggccgtc
     3121 gggcagccac tcgggctgct ccaggaagcc gggccggaag aagttacggg cgtagcggcc
     3181 gagggtgtag gggccggtga gccagccctc gttgcggcgc aggccgtcgg ggtcgacgca
     3241 gagcagcagg ttccaggtgg cgtcggcgcc ctcggtgagc cgggggtcgg ccacggcccg
     3301 ctcggccagc cgcagggcgg tggcgccgcc cacgggctcg ttcgcgtgcg ggccgccgac
     3361 gacgaggacc tggcggctgc cgtggccgac ggagagcagc agcagcgggc tgcccgcgcg
     3421 ggacgtgccg acacgccgca gccgggcgtg tctggggtac cgggcgacga gtgcggcggc
     3481 ccgggcgccc agctcgtcca cggtcgggta gcgcaggagg ggcggcaggg cacacctcca
     3541 cgaagcgggc cgtcgattca cctggtgtgt gcggtgtacg cacagtcagt cacgacttgc
     3601 ggggtacgtc aacaccacga aaagcaaagc agtttcagcc acggagacgg gcacgactcc
     3661 gagtgaagcg cgggccatgg atccacccgg agggctccca ccgggtcgcc gggtcgccgg
     3721 gtcgcgtcag ttcgccgcca ggcggaagga catcccgccg aagccgatct gatcgccctc
     3781 gcggacgacg gccgcgccga tgacccgccg cccgttgacc gtggtgccgt tggtggaacc
     3841 caggtcgcgc agtacccaca tgccgccctg ccggctgagt tccgcgtgca cccgggagac
     3901 cgtctcgtgg ctcagccgca gtccgctggc gggatcgcgc cctatgcgca gcggatgtcc
     3961 ggcgccgggg tggggcagca gcagcttggg cagccgctcg gcccgccacg cccggccgag
     4021 ccgtacgccg aatccggaca ccgcctcgac ggtgccgaac accagccggg acagccggtt
     4081 ctcggtgggc aggtcggcgg tgagcacggc cagctcctcc agacggcggg cggcgagcgc
     4141 cagctccatc cggcggatga acgtgtcgtg cgacaggcgc cccatggcga cgccgtcccg
     4201 gagcacgctc agcgccttgt cgcgctccgc gtcggacagc cgcgcgggat acgtggggaa
     4261 ctcgaaggac gacgtcacgc agctgattgt cggtcagcgg agccggagtg tccagaaaac
     4321 gggaaaaggg cgagcgcccc ccgcgcgagc gtcacgacac ccgccgcgcg cgagggcaat
     4381 ccccagcgga atgatcccct cgtgctggaa catggacgcg ctacatcacg gtgagcagac
     4441 gaaggggaac cgtccgtgca gttcgaggtg tgggcaccac aggccggccg agtgacgttg
     4501 cggtgcgacg gcgccacgcg cgcgctggag cgcgatccgg agcggccggg gtggtggtgc
     4561 ggtgaggctc cggcgcggga cggttcgcgc tacggcttcg cggtggacga cggtccggtg
     4621 ctgccggacc cgcgctcgcg ccgtcagccg gacggccccg acgggctgag cgcggtggtc
     4681 gaccacgggc ggtacgcgtg gcggaccccg tgggccgggc gtccgctgcc cggcggagtc
     4741 ctctacgagc tgcacgtggg gacgtacacg cccgagggca ccctcgacgc cgccgccgac
     4801 cgcctcgaac acctggtgcg actgggcgtc acccacgtcg agctgatgcc gctgtgcccc
     4861 ttccccggtc ggcacggctg ggggtacgag ggggtctcgc tgtgggcggt gcacgagccg
     4921 tacggcgggc ccgaggcgct gaaacggttc gtcgaccggg cgcacgacct cgggctcggc
     4981 gtggtcctgg acgtggtgca caaccacctg ggcccgtccg gcaaccacct gcccgccttc
     5041 ggcccgtact tcaccgacac ccaccacacg ccctggggcg tcgccgtgaa cctggacgcg
     5101 cccggctcgg acgaggtgcg ggcgtacctg gtggacagcg cgctggcgtg gctgcgggac
     5161 taccggctcg acgggctgcg cctggacgcg gtgcacgcgc tggccgacac gcgcgcgtgc
     5221 cacttcctgg agcagttgtc gactgccgtg gacggcctgg cggccgacct ggagcggccg
     5281 ctcttcctga tcgccgagtc cgacctgaac gacccgcgga tcatcacccc gcgcgcggag
     5341 ggcggcctgg gcgtgcacgc gcagtggaac gacgacttcc accacgcgct gcacgccgcc
     5401 ctgaccgggg agtcgcaggg ctactacgcc gacttcgcgc gcgatccgct ggcggcgctc
     5461 gccaagaccc tgatccgggg ctacttccac gacggcacct actccagttt ccggggccgt
     5521 tcgcacggcc gtgcgctgga ccggggccgg gtcgccgcgc accggctgac cggctacagc
     5581 cagacccacg accaggtcgg caaccgcgcc cagggcgacc gtctggcctc cctggtctcc
     5641 ccgggcctcg ccgcctgcgc ggccaccctg accctgaccg cgccgttcac gccgatgctg
     5701 ttcatgggcg aggagtgggc ggcgggcacc ccgtggcagt tcttcaccga ccacaccgac
     5761 ccccagctcg cccaggcggt acggcagggc agacggcggg agttcgccgc gcacggctgg
     5821 cgggaggagg acgtgcccga cccgcaggac ccggcgacgc gtgagcgctc ctgcctcgac
     5881 tggtcggagc cggagcgcga gccgcacgcg cgcgtactgg actggtaccg gcggctgatc
     5941 gccctgcgcg ccgagcagcc ggacctgacc gacccggacc tggccgacac cagggtggcc
     6001 tacgacggca cggggcgctg gctcgccttc cggcgcggcg acatccgggt ggccgtcaac
     6061 ctgggcaccg agccggcggc gatccctctg ggcaaccggc ccgcgcgcgt gctcgcggcg
     6121 tgggaaccgg tggaggggcc gggcgcgaac ggaatactgc gggtgccggg cgagtcgagc
     6181 gtggtgctgg tccaggagtg agcaggggcg ctcaggcggt gtcgtcccgg ccgtcgttgc
     6241 gcagctcggt cacgcgttcc aggaggatcg gttcccaggc gcgtcgcagc cgggtcctga
     6301 gcagcggcac ggtcgcgggc ggcggcccgc cgcagtggcc gtcgagtgcc tccgcgaggt
     6361 ggataaccgc gtcgcagcgg gccagccaca ggccgcgcag gcagggccgg gcgccgtagc
     6421 cggcgagggt ggccgcgcgg acggcggcgg gtgaacccac ggagagggcc agcccggcga
     6481 tgtcctcggc cgggtcgccg aggaccgcgt cgctccagcc gaggacgccg cgcacccggc
     6541 cgtcggcgct gaccacgagg tgcccgccgg tcagcccgtg gtggaccagg accgccgcgc
     6601 ccggctggac gccgagctgg gccgccgcct cccgggtgag ccgttccggc cgcgcggtgt
     6661 cgaactcgtc ggccgcggcg aggcggcgga cggcacgctc ggcggactgg cgcagagcct
     6721 ccagggagcg cggggccgcc cgcggtacgc cgagcgtctc ggcctgccgg accggcacct
     6781 cgcgcaggcc ggtgagcagc gccgcgaggt ccgcctcgcc cagggcggac acgtcgtggt
     6841 cctcgcccga cccgccggcc accttggcgt ccagggtgta cgcgagtccc ggcgcccact
     6901 ccccgtgcgc cacgctggcc ggcagcgcga ccggcaggta cggccggacc agttcgcgca
     6961 ggcgcagttc gcggcggccg cgcaccgcgg tctcccggtc gggggccagc cgcagtacgt
     7021 gccgggtgcc gacccaccag gtgtcgggtg cgacgccttc ggcgaccggc cggacgtcgg
     7081 gttccgtgct cccgcccagc agggagcgga ccagtcggcg gacggtgtcc gcggtgggtg
     7141 tcggtgcctg ggtcatgtcg cgccgtcgtc ctgaagggtc tgccggggcg ttcggggtcg
     7201 gtccgtcacc ggtcactcga cgacgaccat ctcccgggtg gtgtcgttga gccgcctgcc
     7261 gccgtcctcg gtgacggtga cgatgtcctc gatgcgtacc ccgaaccggc cgggcagata
     7321 gacgccgggc tcgacggaga agcacatgcc gggcaccagg ggccgctcct cgccctcgat
     7381 catgtacggc ggttcgtgcg tggtgacgcc gatgccgtgc ccggtgcggt ggatgaagta
     7441 ctcgccgtac ccggcgccgg cgatgaccgc gcgggcggcc cggtcgacgt cctggcaggc
     7501 ggcgccgggg cgcaccgcgc aaaagccggc ctcctgcgcc tcgcggacca ggtcgtgcac
     7561 ccggcgctcc tcgtcggtgg gtgcgcccac gtggacggtg cgggaggtgt ccgagccgta
     7621 gccgtccttg aggccgccga agtcgaggac gatcatgtcg ccgtcctcga tgacgcggtc
     7681 gccgacctcg tggtgcgggt tggcgccgtt gggtccggag gcgacgatgg tgaagtcgac
     7741 ctgggagtgc ccgaaccggc gcagcaggtc ggcgaggtcg gcggcgacct cggactcccg
     7801 gcgcccgccg aagcggaccc gccggatctc ctcgaaggcg gcgtccgcgg ccgcgcccgc
     7861 cgccgccagc agctccagct ccgccgcgtc cttgacggcg cggagcatcg gcagcgcctc
     7921 ggtgagggag gcgtacgagg tgtcgggcag ggtgcgctgg agcgccagca ggtgcatggc
     7981 ccaggcgttg tcgctgatgc cgaagcgtcc ggatccgtcg aggagggcgg cggtggccgc
     8041 gtaggggtcc ttgccgtcgg tccagtcgcg cagggtcagg gcgggggcgc cggccgcctt
     8101 cgccgcgtcg ggggcctcga gcgtcgggac gacgagcacg gggtcgcggt ccggggcgag
     8161 gacgagcagc gtgagccgtt cggtgtccgc cgtgggcgcg tagccggtga gccacaccag
     8221 gtccgggccc ggggccacca gcagcccggc gaggccggcg tcggcggccg cccgggcggc
     8281 gcgctccata cgggcccggt agtcgtcggc ggtgaaggaa gcggcggggc tgctgccggt
     8341 catccgggcc tcccggggcg gaagagtggg cggaggagtg aagggaccac gggcagcatc
     8401 ctgcccgcag gacgggggcg acgcgagccg attgggattg atcgaccctg acgactaatg
     8461 gttgtatgtc actcaagcat taacatcggg ggtgtcgcgg tccgggcgcc cggaggaggc
     8521 cgacaccgtg ctcgtactcg cgcacatcag cgatctgcac ctggacggaa gcccgcgggc
     8581 gacggagcgc gccgagcggg tgcgcgagag gctgtggcgg ctgccggggc gggtggacgc
     8641 gctgctggtc accggggaca tcgcggacca cggcacggag gcggagtacg aggaggccgc
     8701 ccgcgtcctg ggcctgcggg acggctccgc gccgttcccc gtactgacct gcccgggcaa
     8761 ccacgacagc cgcgccccct accgcaaggc cctgctcggc cgccccgccg ccgacggccc
     8821 cgccaacgag gtgcacgtct tcgacggcgg cgccgtcctg atgtgcgact ccagcatccc
     8881 gggcagcgac gagggggagc tggacgggga gacgtacgac tggatcgagg cctcgctcga
     8941 cggtctcgac cacggccttc cggccctgct cgccttccac cacccgccca cgcccgtgca
     9001 ccatcccctg cccgactcct accggctgcg ccaccccgag cgcctggccg cgctgctgga
     9061 gcgcaggccc gggatcgccg ggctgatcac ggggcacgcg cactcgcccg cggccaccgt
     9121 gttcgccggg cggccgctgg tggtgggacc cggggtgacg tggacgctgc ggctgccctg
     9181 ggagggcgag caggtcgcgg accgggacgc gccggtcggg ctcgccttcc acgtgctgga
     9241 cgacgccgga cggctcacga gccacttccg cacggtcacg tgacgacgcc cggtacggcc
     9301 gtcagctgct ggtagccgcc gctgcggtgg cgcacggtga gcttgacctc cttgcccggc
     9361 ccggcgctgg ccacggcgtg cgccaggtcg gtcgccgagt cgacgcgggt cgtgccgacg
     9421 gcgagcagta cgtcgccccg caccaggccc gccgcgtacc cggggcccgg cacgtggacg
     9481 cccacgaccc gggccccggg cttctcgtcg tccacggctt cgaccccgag ggtcgcgccg
     9541 gccggtgccg gggaggggga ccggccggcg gacggaccgg ccgacgggtg cgccggggcg
     9601 ccccgggtgc ccgtcgccgt cccggtggcc ccctgctctc ccgctcctcc ggcccctccg
     9661 gccccgcccg ggccctgcgc cgcggcccgc tgccgcagtt cggcgagctt gctcatgccg
     9721 atcaccgtgg cgcccaccgt gccgagtccc acgcccgtga ggagcaggac ggccgcggcg
     9781 agcacgccga gcagcagggt ggtgagccgc cggcggcgcc gacggccggt gtgggggtgc
     9841 cgggcaccgt cgggttcggt gccgggcccc ggatcccggc cgggcatcgg cttgggacgc
     9901 aacgctgtct gttccatgga tcgcctccgg caggtgctct acccggcgca ccggcccgtg
     9961 acgagccacg aaagagtgag actgaacgtc cgtcagcgcg tcagtgcgtc agtgcgggac
    10021 tgctcctcgg cacgggcggg gccgggatcc ggtccggcag gaagccgtgg gtgcgtcccg
    10081 ccaggtactc ggccttgtaa cgggggacgt tccggtgcca gttgaggatg cctgccatcc
    10141 agttctgcag gtcggcgacg tagccgcgca tgacggtccg cgcctcctcg gagagctgga
    10201 agtcgtcgta gacgacgggg agttcgtgcg cgacgacgtg ctcgaactgg cgcatgcgct
    10261 ggttcatcag gtcctgcacg acgcccaggg cggccggata gtcgacgccg aagaagttct
    10321 gcacgacgag gaccgcgttg tggatctcgc cctcgtactc gatctccttc tggtaggaga
    10381 agacgtcgtt gagcaggcac gcgtagtcga tcgccgcgtt ctccagggag cggacggggc
    10441 cggtgcggta gacctcgggc ggcaccgccg ggccgtgtcc ggcgcggcac aggcccaggg
    10501 tgaggtcgga tccgaaggtg gcgcgccgca tctccaggta gtccacggga tcggggacac
    10561 ggttctggat ctggttggac agctcccaca gccaggcctc ggtcatgtcg tcgacggcct
    10621 tcttcagcgg gcgccgctcc tcgggcgtca taccggccgt cgtgcgcacc cacaggtcga
    10681 tcagggagcg ttccatcgcg ttgccgggcg gtgggacggg ctcgccgtcg agcggcatgc
    10741 agtccgacag gcgggtggtg gtcagccggg cggcggcgag gtcccggcgg tggccgtaga
    10801 ccagcgggta gtagtcgtcg ccgtacgtgc cgaaggccag ccagccggag gcgaggtcga
    10861 gctggtcctg ggtggcgtcc gggtcgagtc cggcggcgca cagcggaagg tcgcagctct
    10921 ccagcttgtc ctcgtcccag acgccctcgc tgaggatgcc catctcccgg caccactcgg
    10981 acaggtgccg ccgggcaccg tccagggcgg ggctcagctc cagcgggaag ggcatgcgga
    11041 tgtcggggat gacggacggg ccgaccttct ggaagggcac gtacgtgtag gagcgggccc
    11101 gttgggcgac cgcgtcggcg agcagtgctc ccacgtccgc cgcggaggtg ccgggcccgg
    11161 tcagcgcctg ccagccggcc aggggccgct cccccttgtt catgtagcgg ctggaacgca
    11221 tgtgccactc gtggccgccg gactgccagt cctggaggcc cttcgtgtac gcgccgacgg
    11281 cggcgacctc cggcggggtc aggccgttct ccagggcgac ggcgggcacc tcggtgaacg
    11341 cggtgtgctc gaactggtgc agccgcgagg tgaggacgtc gttgaccagt tcggcggcct
    11401 cctgggtggt gcagccgaag aaggtctcca acaccagtac cccgttgctc agctcgccct
    11461 cgtcctcgac ctcgcgctgg taggagaaga ggtcgttgcg caggtgcacg gcgtcggaga
    11521 acgtctccat cagcaccctg agcggcctgg tcccggcgac ggcggcgggc acctcggcgg
    11581 tcgcgtactc cacgagcccg gccgaccacg gggcgccgcc gaccttgcgg cgcatctcga
    11641 tgtactcgac cgggttggcg acccgcccct cgttgatgtt ggacagctcc cacatggact
    11701 cgttgaggag gtgctcggtg gcgacggcga agcggcggcg ccagtccgcc gacatcgcgg
    11761 gcaccgtgcg ggtccacagg tcggcgagtc cggcctccac cgggttccgc ggctcgggca
    11821 tcccggcggc gtcgtcgagc ggcatgaaca gcgggagccg gtccaggtgg gccttgccgg
    11881 cgaggcggtc ctggctgcgt ttgtacttct ccaggaagtg gtcgtcgaag aagaagaccc
    11941 acacgtacca gtcggtgatg agggagagcg ccggcccgtc gcagtcgggg tgggtgtagg
    12001 cgcacagcag gccgtagtcg tgggcttcga ggtcggactg ctcccagacc ccggagccct
    12061 ccagcatgcc catctcgcgc gcccacgtcg tcgagtgggc gcgggcctcg tcgagatgcg
    12121 ggttgagccg tgcggggtgc ggcaggtaga agtgcgggag ttggaagggc tgttgcgtca
    12181 tggcccggcc ctacccaggg cccttcgacc gcatccaccg ggccgcacat gatcacacca
    12241 tcgcgtgaat cagcccggaa tgcgggaact tctcccgccg ttctccctcg gctgcccgcc
    12301 gctccttctc ggctccctcg cggctccttc tcagctcctg acctggatca gggcgtgcgt
    12361 gccgctcgtc cgccagcgcc gctcgccgct cgcgtccaac gcggcctcgg tcttcgcgtc
    12421 gagcccggtg accacgtcgg acttcagggt gcgcagcgcc gcgaccgggc cggggaagta
    12481 cgcggtgacc cgcgcgaagg aggtggtcgg cggccaccac cggtcgccca ccaggcgccg
    12541 gtagttcagg tcgcccttga ggacggtgac ggtggccgcg gcgaagtcct cgcgcaggtc
    12601 gtcgggcatg tccgcgtagg gcagcggggc gcaggagaag gggtgggcgc ggacggtgac
    12661 gcggccgtcg gtcagcgcgg tccagagccg ctcgccgtgg gccgcggccg cgccgcccgc
    12721 cgcgaccagc cgccgcaggg cgtcgagcac gtcggtgggt gtggcgtcgg agacgtagta
    12781 cgggtacggc ttgacgtgca ggacggcctg gtcgacgcgg ccctcggcga ggaggtgcga
    12841 gacgaggagc aggtcgggga cgagttcgcg gcccgcgttg tcggcgacga ggcacagcgt
    12901 ggccggaccc cgctccgcgg ggcccgtgcc gggggccggg agcagggacc agagggcgtc
    12961 gctgtcgtcg gcgacgagtg cctccaccgc gccctcggtg ccggcgcccc ggtcggagag
    13021 gcggaagccc aggtcggcgc ggttgcccca cagcgagccg tgcagcagcg cccgggtccg
    13081 ctcctcggtg ggcaactcgt cgagaccgtc gagcgcggcg agctcctcgt ccgtctccgg
    13141 cgcgtcgagt tcggccagtt tggcgggccg gaaggggtcg acgccctgcc aggcgccggg
    13201 accgaagtag ccgacggcgt cgaggagccg gcggtagaag tggctctcgg cccacagcca
    13261 gggcacgtcg taccaggagc gtcccgcgta cgcgtccatg ccccaccgcg cccagcggtc
    13321 ccggtcgcgg ccggtggggt cggcgtcggc gggcagcggc tcgaccacgc cgtcggcgca
    13381 gctcgcgagc aacgcgtcga gcgcgcgcag ccgttcgggg ccgaagggga aggcgtcccg
    13441 cacctgccgc acgatggcgg ggtgccgctc ggcgagcacg ccgtgcggga aggagccggg
    13501 ctcgtcgccg aggatgacgg gtgcggtcac ggacggggtg tcggccatgc gcgtcaccgt
    13561 accggtcgga ccgcacgcgt ccccggttcc gggcggtggg gccgagcgcg tccccggttc
    13621 cgggcgatcg ggccgagcac acgcccggca ccgggcaatc gggccgagca cgaccccgcg
    13681 ccgggcaatc gggcgggacg cgacccccgc gccggacggt caagcgggac acgaccccgc
    13741 gccggacggt cagcccaagc acgacccgcg ccggacgatc agcccgggca cgaccccgcg
    13801 ccaggcgatc ggcccgagca cgaccccggg ccggacggtc aggcgagacg cgacccccgc
    13861 gccagacggt caagccggac gcgaccccaa tccggacggt cagcccaagc gcgacccgcg
    13921 ccggacgatc agcccgggca cgaccccgcg ccaggtgatc ggcccgagca cgaccccggg
    13981 ccggacggtc aggcgagacg cgaccccaat ccggacggtc aagccggacg cgaccccaat
    14041 ccggacggtc agcccaagcg cgacccgcgc cggacgatca gcccgggcac gaccccgcgc
    14101 caggtgatcg ggccgagcgc gaccccattc cgggcggtcg gcccgggcgc gaccccgtgc
    14161 cggacggtca ggccgtgccc gtctcctgtt ccaggcgggc cgcgagggtg acgtagcggg
    14221 cgcgccgggt caccgggacc atgccccgga tcaggatgta ccacatctcc gcgaggcggc
    14281 ggggctcgcg cccggccggt tcgagggtgc cgcccacgac gcgggtgccg acgacggagc
    14341 agacgagggt gtgggcgacg gagtcgacgt cgatgtcctg gtgcacgtcg gactgccgca
    14401 ccgcgtccag cagccgggac gtggcgatct cccgccactc ggtgaagggg tgcggcaggg
    14461 gcggccgtac cggtacgccc gcggtggcga gccgcagccc ggcccgcagc accggtccct
    14521 gtacgcagag ccgggccatg ccgaaggtga ggcgcatcag cgcctccagc gaggagtagc
    14581 cgcgcccgtc caggtccttc gccagccggc gggaggtgcg ggactgtatc tccaggatgg
    14641 cgtgcgcgag gtcttccttc gccgcgaagt ggaagtacag ggcgcccttg gtgaccccgg
    14701 cgtgggcgac tatctcgctc agggtcgtcg actcgtagcc gcggcggtcg aacaggtcgg
    14761 ccgccgcacc gatgatcgtc gcgcgggtct gctcggcgcg tagctgcctc gccatcggct
    14821 ggattctccc gggctggaac tcaacagacc gtgccgcctg cctttacccc ggcacacgat
    14881 aacccaccgg ctaactgccc gtcagatcag cttcccggcg ccccgggcgc ccacggacgc
    14941 cgccgggcat accgcccggc attccgcttc ggcccgcttt cgccaccccc gttcatcacg
    15001 atgcggcacc gacaactcag agcagttcgc tggtcacttg actaccagcg gtcacacacg
    15061 gtttgctccg gccaggcgag tttcacccgg ttggcgcact gacccgcggc tccgggccgg
    15121 cccgtcccgt tcctcctgct cggccgcaca gcgaggtgcc cccgccccca tgagtacagc
    15181 tcccccgccc acccactccc ccggacccgc gcgcgccgcg gccctcaccg cggccgtctg
    15241 cctgctggtg gccggctgct ccgccctcgg cggggacgag gacggctcgg cggcggacgc
    15301 cgcgggcggg tccggcggcg accggatgaa gatcgtcatg gtcacccacg gcggtgaggg
    15361 cgacgccttc tgggaccggg tgcgcaaggg cgcggaggcg gcggccgcca aggacggcgt
    15421 cgacctgacc tacgccgggg acgccgacac cgccgaccag gccgacctcg tgcgggacgc
    15481 catccgtgac aaggccgacg gcatcgccgt gaccctggcc aaaccgcagg cgatgaaggc
    15541 accggtcgcc gaggcgaagg cggccgggat cccggtggtc ggcctcaact ccggcatcga
    15601 cgcctggcgg tccaccgggc tcctggagta cttcgggcag gacgagagcg tcgcgggccg
    15661 cgccgtcggc gacaagctgg acgacctccg ggcgaagcac gccctgtgcg tcatccacga
    15721 gcgcggcaac gtcgccctgg aggcgcgctg cgccggtgtg aagaagacct tcggcggcga
    15781 gaccgagatg ctctacgtcg agggcaccga catgaaggcg gtcggcgcgg ccgtcacggc
    15841 ccggctgcgg caggacccca gcatcgacga agtcgtcatg aacggcgcgg cgttcgccct
    15901 caccgcggtc gaggcggtcg acgaggcggg cagcgacgcc cacgtcgcca ccttcgacct
    15961 cgacaacgac ctggtggccg ccgtcaaacg cggggacgtc cagttcgccg tggaccagca
    16021 gccgtatctg cagggctatc tcgcggtgga cgcgctctgg ctctaccgca ccaacggcaa
    16081 cgtcagcggc ggcggcgtgg cccccgtgct gacgggcccc gcgttcgtga cccggaccaa
    16141 cgccgactcg gtcgccgagt tcgccgcggg cggcacccgg tgaccgggcc ccgcggccgc
    16201 cggcacctcc gcacccccgc caccccgccc cactgatcgc ctaggacgac gatgcctgca
    16261 cggaagtcac ggaagaaggg tgcccggcgc cgcctcggct ccatacgtct ctccctgatc
    16321 ctcctggccc tggtccccgg cgtcaccctc gcggccgtgt ggggcgtcac gacgatccag
    16381 atgttctcgg agggcctgcg gctgcgcgcg cagacgcagc tgagccgcga caccggcgcc
    16441 atgggcaccg aggccaccct ggccctgcag aaggagcgca gcctgtcggc cgcctggctg
    16501 gccgcaccgg acggcgaccg gagcgaactg gacgcgcagc ggaagaagac ggacgcggcg
    16561 gtcgcgcagt tggtcggcca gtccgacgcg atcgagagcg cgcccacccg ggtctcggac
    16621 cggctgtact cggtgctcgg ctcggtgggc agcctggagt actaccgcaa ccaggtggac
    16681 gaccccagcg acatcaccgc cgagcaggcg ctcgaccagt acacctcgat cgtcgacgag
    16741 cagatccacg ccttccagga gctctcccag gtcgacgacg gcgacctcac ctcccaggcg
    16801 ggcccgctgg tcgccctgga gcacgccgcc gagctggtct cccaggagga cgcccggctc
    16861 accctggcct ggccgtccgg ccggatggac gaggagcagt ggtcccggtt cgcccagctg
    16921 gtgcacaccc gccgctggct ggtgcaggac cagatcgtcc cctctctgac cggcagtgcg
    16981 aagacccaga ccgagcggat cctcgccagc tccgagtgga agtccctgca ggacgtcgag
    17041 gaccaggtgc tcgaggcccg ttcggcgggc cggggcgacc ggatcgacct gccggacgca
    17101 cggcagcgct ggatcaccgc cttcgagaag atctccaccc agtacgggca gctcatccgg
    17161 cagcagaccg acgggctcct cgaccgcagc gccgaggagg cccggggcct gctgatcaag
    17221 gccggtgtcc tcagcgcggg cggcctgatc gccctgctgc tctgcatcgt gatgtcctgg
    17281 cgcatcaccc gctcgctgtc ccggcggctg cgcgggctgc ggctggccac cctgagcctg
    17341 gccgaggagc ggctgcccga cgtggtggcc cgcctcgaac ggggcgagac ggtcgacgtg
    17401 gagtccgcga cacccccgct ggactacgga cgggacgaac tcggccaggt cgcgcaggcg
    17461 ttcaacacgg cgcagcgcac cgccgtgcac accgccgtcg aactcgccga cacccggcgc
    17521 ggcttccaga aggtcatcct gggcatcgcg cggcagagcc agaacctcgt caacatgcag
    17581 ctcggcaaac tggacgccct ggagcgggag cacacggacc ccgagatcct caagggcctg
    17641 tacgagctgg actccacggc cagtcagctg cggcgctacg aggagaacct cgtcatcatc
    17701 agcggcgagc agccccggcg cacctggcgc gagcccgtgt cgctggtcga catcctgcgc
    17761 agcgccgtcg gcgaggtcgc cgagtaccag cgggtggagc tgcacgccga cgaggaggtg
    17821 gccctcgccc cgcccgcggt ggccgacgtg atccacctcc tggccgagct gatcgacaac
    17881 gcgaccgcgt actcccccgc gcccaacccg gtcggcgtgc gggcggcgct ggtggccaag
    17941 ggcctggccg tggagatcga ggaccgcggg ctcggcctgt cggaggagga ctacgcgtcg
    18001 ttcaacgccc agctggcggt ggccccgcag ttcgacgtgg tggcgctcgc cgacgacctg
    18061 cggctcggca tgttcgtcgt ggcccgcctc gcgcaccggc acggcatcac cgtcacgctg
    18121 cggccctcgc cgtacggcgg gaccacggcg atcgtgctga tcccgcacga catcgtggtg
    18181 cgggagccgg ccggcggggc ggacggcacg ggtgccgcgg cgaacggcgc gcgggccccc
    18241 tgggtcgccg cgcccaccgc gcgcgactcg gccgacccgg cgggcccggc catcgacacc
    18301 ggcagcgtca ccggcaccgg caccgagacc ggccaggcag ccccgggcgc cgcggccggg
    18361 cggtccgcca cggcctcggc ggcggcgggg gacccgtccg gcgacccccg gccggtgcgc
    18421 cccgtacggt cgtcccggcc ggcgcccgcg ggcccggccg cagccggggc gggttccccc
    18481 cgcggccact ccggcgcctc cgcgcacgac gcctccgacg ggcgcggcgg actggcgccg
    18541 ctgccccgcc gggtaccgca gaccagcctc gccgccgaac tgcgcgacga ggatccgggc
    18601 ggccgccggg acggctcgga ccacgcggcc gccgacgcct acgccgactt cacggccgag
    18661 cgcgccgcgt cgtccctcgc cggtttccag cgcggcacgc tgcgggccca caccgatgac
    18721 gacgcggacg aagcagccga cccgcgcgca gcacacgaag cagacgaggc ggccgaaggc
    18781 gtcggtggcg cggacgaccg cgccaccgac gggcacgcgc tctcctccgc cgcccactcg
    18841 accccgaccg ccgaccgccg accgcccacg aaggacacgc gatgacccga ccctcccccg
    18901 ccacgcacac cgagctggac cagttgctca ccggactcgt ggagcgggtc gccgacgtga
    18961 accaggccgt ggtgctctcc gaggacggcc tggtcgtcag caagtccacc gggttcctgc
    19021 gggacgacgc cgagcggctg gcggcgaccg cgtcgggcct gatgagcctc agcaagggcg
    19081 tcagcatgga cttccggggc ggcccggtgc gccaggcgct catcgagatg gccaacagct
    19141 acctgatact cacctccgcg ggccccggcg cgcacctggt cgtgctcacc gggccgaacg
    19201 ccgacgtcgg cgtggtggcg taccagatga acatgctggt gaagaagatc ggcgagcacc
    19261 tgagcgcggc accgcgggcc accgccggcc ccggcgagtg acgtgaccgg aggcgacgct
    19321 gcgggccggc tcgtgcggcc gttcaccctg accggcggcc ggaccaggcc cagccgcgcc
    19381 gacttcaccc tcatcacgac ggtgaccgcg atcgacccgc agccctcccg ggcggcgcgg
    19441 ccgcagcccg agcacctgcg gatcctgcgg ctgtgcgccg agccgatggc cgtggcggag
    19501 ctggcggccc gtctcgacct gccggtgagc gtggtcgtca tcctgctctc ggacctgctg
    19561 gaggccggcc gcatcaccgc ccggccgccg cacccggtct cccgcgccac cgacgacctg
    19621 gacctgctgc agaaagtgag ggacggcctt ggccggctct gagcgcgtcg ccgagacgcc
    19681 cacggcatcc gcacgctcca ccgctcccga ggcggtgaag atcctgatcg cgggcggttt
    19741 cggcgtcggc aagaccacca tggtggggtc ggtcagcgag atcgccccgc tgcgcaccga
    19801 ggaaccgctg accgcggcgg gcctggacgt cgacgacctc gccggcatcg aggagaagcg
    19861 ggccacgacg gtggcgctgg acttcggccg gatcaccatc ggccgggacg tggtgctgta
    19921 cctcttcggt acgcccggcc agcagcggtt ctggttcatg tggaacgacc tggcgatcgg
    19981 ggcgctcggc gcggtggtcc tggtcgacgt ccgcaggccc gagtcgagct tcgccgcgat
    20041 cgacttcttc gagcggcggg gcattccgtt cgtcgtcgcc gtgaacggct tccacggccg
    20101 gcacccgtac ccggcggcgg agatccgcga ggccctcgcg ctgccggagc acgtgcaggt
    20161 gctgctgtgc gacgcgcggg agcggacctc cagccgggac gtcctcatcg ccctgatcga
    20221 ccagctgatc gacgccgcgg ccggggccgc ggcgtcctag cgggtcgtgg cgaggcgtct
    20281 cagggcttcc gtcagacgag acccgcggac ttcagccact ccttggccac gtccagcggg
    20341 tccttcttgt ccagctggac ctgggcgtcc aggtccagga gcgtctcggt gtcgagcttg
    20401 gcggagaccg cgttgagcgt ggccacgccc tcctcgttca gcccgtcctt ggtgaccagc
    20461 ggggtcacgt tcgcgtggcc gaagaggttc tccgggtcct tcaggacgac gaacttctcc
    20521 ttgatgatgg tcggatcggt ggtgaagacg tccgccgcct gcacgtcgtt cttggtcagc
    20581 gccgactggg tcagcgggcc gcccgcgtcg agcgccttga aggacttgaa cttcagtccg
    20641 tacaccgact ccaggccctt gagcccctgc tgccgcgtct ggaactcggg cgagccgccg
    20701 atcaccaggt ccggtgcgac gtccttgagg tcggcgaggg tcgactcggc ggtgaggccg
    20761 tgcttcttcg cggtctcggc gttgacgctc accgagtcct tgttctcggc cggtgacgac
    20821 tccagcagcg tcagcttctt gtcgagcttg gccttcgccg cctcgttcac cgcctccacg
    20881 gacttctgcc gggccttcgg gtcgaggtag gcgagcagcg agccgttgta ctccggcagc
    20941 accgtgacgg agccgttctt catcatgccg taggtcgtct cccggctgcc tatgttgtgc
    21001 ttgtaggtga ccttgaggcc cttggccttg agcgcctccc cgtagatgtc ggcgagcagg
    21061 gtgctctcgg cgaagttgtt cgagccgacg acgacggtgc cggcctccgc cttgtcaccc
    21121 gcgagcgggt tgtcggaggt gccgtcggag tcggaggaac agcccgcgag cagcgccgcc
    21181 gcggcggtga gcgcgacggc cgccgcgccg gtgtgcctgg tcctggacct gctgctcttc
    21241 gcggtgaaat tcatccgtcg atccaaacga tccgcttgcc ggtgagtcaa gtacggcctg
    21301 gttacggttt ctccgcggcc cgggcgctca gcgcctgcgc acccccggcg agaccgcgaa
    21361 ccgtcccgcc gcccagaaga gcgcgagggt gaccagggcc aggacggcca ccagcgtggc
    21421 gccgccgacg accttctcgt agtcgcgctg gtagagcccg tcgatgatgt agcggccgat
    21481 gccgccgagg ctgacgtagg cggcgatggt cgccgtcgac acgacctgga tggcggccga
    21541 gcgcagcccg ctgaggacca gcgggagggc gaccgggagt tcgacccgga agaggatgcc
    21601 cgactcgtgc atgcccatgc cccgggcggc gtccaccggc gaggggtcga cggagcggac
    21661 cgcctcgtag gtggtcacga ggatgggcgg gaccgcgagc acgacgagcg ggaccatcac
    21721 gggcagcagg ccgatgccga cgacgacggc gatcagcacc agcagaccga agctgggcag
    21781 ggcgcgggcg gcggtggcga cgaaggcgac ggcgttgccg ccgcgtccgg tgtgcccggt
    21841 cagcagcccg acgggcagcc cgatggcggc ggcgagtccg agggccatca gggtgtactg
    21901 gacgtgttcc agcaggcgcg tggggatgcc gtcgtagccg tgccagtggg cgctgtcgct
    21961 gaagaaggcg ttgacgaagt cgaggacgtt caccgggtcg ccgcctcctg cggttcgggc
    22021 cgctcctgcc gcacggcggc gtgggccctg gcgcgccgcc ccttgccgcg cggcatccac
    22081 ggggtcagca ggttgcgggc caggacgagc agcgcgtcgc acaggacggc cagtacggcg
    22141 gtggtcagga ccgagttgac cgccagttcg ggccggccgt a
//
