LOCUS       NZ_BMVQ01000001        10216 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces anthocyanicus strain JCM 4739 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVQ01000001
VERSION     NZ_BMVQ01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces anthocyanicus
  ORGANISM  Streptomyces anthocyanicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces violaceoruber group.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1401614)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:14:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,934
            CDSs (total)                      :: 7,858
            Genes (coding)                    :: 7,681
            CDSs (with protein)               :: 7,681
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 177
            CDSs (without protein)            :: 177
            Pseudo Genes (ambiguous residues) :: 0 of 177
            Pseudo Genes (frameshifted)       :: 73 of 177
            Pseudo Genes (incomplete)         :: 130 of 177
            Pseudo Genes (internal stop)      :: 16 of 177
            Pseudo Genes (multiple problems)  :: 37 of 177
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:48:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 727455
            Orig. end                         :: 737671
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVQ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10216
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="6"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10216
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10216
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5216](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5216
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(93..272)
                     /locus_tag="IE283_RS03275"
                     /old_locus_tag="GCM10010348_06790"
     CDS             complement(93..272)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389406.1"
                     /locus_tag="IE283_RS03275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_06790"
                     /product="hypothetical protein"
                     /protein_id="WP_003978111.1"
                     /transl_table=11
                     /translation="MTTDTDGKPAVRRLETGWSKARRLRSRGVMRTCVPAVEDGSTVRA
                     PQSGQESNIVRGED"
     gene            complement(373..2859)
                     /locus_tag="IE283_RS03280"
                     /old_locus_tag="GCM10010348_06800"
     CDS             complement(373..2859)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978110.1"
                     /locus_tag="IE283_RS03280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_06800"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_003978110.1"
                     /transl_table=11
                     /translation="MPHKRCNGEVAGEDAAERGPRTLRAEGALNAIVAGPVPQERLRVI
                     LEQALVFAGASFAALYAPGDDRELLCLVESAGVPRSLYGVRDSYPASGGSPVADAHRAG
                     EAVWIGPEEFAGSAESRHVPSSGFSLAVLPVRGDGGGCFLALTERPDGFDTDDRTCLEA
                     IAEAMTCPAPAETAARAETGDLQPDAFTLTMDSGRVEVGDDILRLFGLAPGEFDGKVET
                     LLGLTVPEDLPSLMSVTESDHMTIGERELEFRVLQPTGPPKWLRLSGRLLPGGEGRPAL
                     LVGTVADASTLRPDVTDVARVQRLAAALATAGTVRDVSQAVVAALRRPLRADRIALAEL
                     ENDRLVVTVLDPPDPESWPELWRLEWRTEWPDAPVRAMPTLAAALREGRARIWPAGTGD
                     LEPALADVGPGGLAVLPLPAGGRMAGACLIGWDTPHDFGPDERALLTASAGLAGQALMR
                     AHAFDAEHELVGMLQRQLLPRRLPKLPGAVAVARYLPSTAGLELGGDWYDVIPLPDHHV
                     ALVIGDVQGHSAGAATLMGQMRTALRAYAVEGHPPDVVVSHANRLLTGMETDLFATCVY
                     VDLDMEEGSAWCVRAGHLPPVLRHPDGSTEIAEVEGGPPLGVVTQADFPMSPLRLRPGT
                     LIALTTDGLVETPESDIDEGMDRFAHALAVSAPDHLGLVADALLGNARRNDDVALLLVR
                     YDGMALRPLRESWSVWRLPEAVRHARRFTRRTLRTWGVPDDDIDGVLLIVSELVTNALV
                     HTDGKVRLDLTLIGGRLRVAVADASPRTPVKPTSIGWEATGGRGILLVEAMSATWGTLP
                     VSGGKQVWSEIPVGGG"
     gene            complement(3097..4419)
                     /locus_tag="IE283_RS03285"
                     /old_locus_tag="GCM10010348_06810"
     CDS             complement(3097..4419)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978109.1"
                     /locus_tag="IE283_RS03285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_06810"
                     /product="S1 family peptidase"
                     /protein_id="WP_189282726.1"
                     /transl_table=11
                     /translation="MSHKRIPKRRAAMAAGGVVALGAAAILLPNANASQDGGSSDDAAA
                     APRTLKAADASDLAARLAGLLGDSFAGSYYDSGARQLVVNVVPGDNNQVVVQAEKAGAK
                     VREVDNSMGELRGGAQTLKAEAGIPGTAWAIDPRTNKILVTADSTVTGDRWDRLESTVD
                     GLGSGMATVRKSAGTFKTFASGGDAIFGGGARCSLGFNVTAGDGSPAFLTAGHCGVAAD
                     QWSDAQGGQPIATVDQAVFPGEGDFALVRYDDPATEAPSEVDLGDQTLPISGAAEAAVG
                     QEVFRMGSTTGLADGQVLGLDATVNYPEGTVTGLIQTDVCAEPGDSGGSLFTRDGLAIG
                     LTSGGSGDCTVGGETFFQPVTTALAAVGATLGGEDGGAGAGDAGGAGAGAGEEGDAGGA
                     GDAGDGGAGAGDKGDKGDTGDAGDAGDGAPVGGRDGSGLTG"
     gene            5001..5216
                     /locus_tag="IE283_RS03290"
                     /old_locus_tag="GCM10010348_06820"
     CDS             5001..5216
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128984.1"
                     /locus_tag="IE283_RS03290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_06820"
                     /product="hypothetical protein"
                     /protein_id="WP_003978108.1"
                     /sec_met_domain="strepbact (E-value: 3.9e-38, bitscore:
                     126.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVETVEISDADLDNVSGGLNVNAVGTVTGLVDGIAPVSGL
                     LNTAVGTVEGVTGLNTAPVTGLVAGL"
     gene            5334..6140
                     /locus_tag="IE283_RS03295"
                     /old_locus_tag="GCM10010348_06830"
     CDS             5334..6140
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="IE283_RS03295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_06830"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_003978107.1"
                     /transl_table=11
                     /translation="MQFRQQALAKLQSPEELDLPVRFARPQGWLVLSVTLIAMAAASVW
                     AVGGSVTSTVSAPAVLTHGQGSYLLQSPVSGQVTAVLARPGQRLAADAPVLKVRTAKGE
                     TVVRTVDAGRVSALAATVGQIIATGANVASVEKVAHAGDPLYATVYVPAENAAAIPAHA
                     SVDLTVQSVPTQQYGVLHGEVKSVDRSAQSAQTIGAFLGDSALGEQFTEDGRPVAVTVR
                     LATSKSTKSGYAWSSADGPPFELTSMTLASGSIRLADQRPVDWLLP"
     gene            6137..8359
                     /locus_tag="IE283_RS03300"
                     /old_locus_tag="GCM10010348_06840"
     CDS             6137..8359
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978106.1"
                     /locus_tag="IE283_RS03300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010348_06840"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_193484480.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.7e-40, bitscore:
                     133.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAQETRGRRRAAPPRRSVPKSRARTVRTPTVLQMEAVECGAAS
                     LAMVLGHYGRHVPLEELRIACGVSRDGSRASNLLKAARSYGFTAKGMQMDLAALAEVTA
                     PAILFWEFNHYVVYDGMGRRFGRRGVFINDPGKGRRFVSLEDFDGSFTGVVLTMEPGDG
                     FTRGGRKPGVLGAMPARLRGTAGTLPAAVLASLLLVAVGAAVPALSRTYIDMFLIGGQT
                     SLLGVLFASMGACVLLTMVLTWLQQANLLHGRIISSTLSSARFLRHLLRLPVTFFSQRS
                     PADLVQRLQSNDAVAETLARDLAAAGVDAIVVVLYAVLLYTYDPQLTFVGIGVALLNIL
                     AMRVVIRLRATRTAKLRADTARLTNTAYTGLQLIETMKATGGEDGYFRKWAGQHATTLE
                     EQQRLGVPSAWLGVVAPTLATLNSGLILWIGGMRAVEGHISVGLLVAFQALVVRFTAPL
                     TRLNGVAGRIQDFAADVARLKDVENFRADPLYDRPGDGDSTRRLRGHVELQNVSFGYNP
                     LDKPLLSGFDLTVGPGQQVALVGGSGSGKSTVSRLISGLYAPWDGVIRIDGQRLDDIPR
                     GALASSVSFVDQDVFLFEGSVRDNVALWDPSIPDDAVVEALKDAALYDVVTRRPGGLHS
                     PVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSALDAETELVVMDNLRRRGCACV
                     VIAHRLSTVRDSDEIVVLDHGTVVERGRHEELLARGGAYAALVRER"
ORIGIN
        1 gtgcccctcg cggtccgcgg ccgccccgca acgcgcaccg cgccggcacc aaggccggcg
       61 cgctgggcgg tgtcaccacc ctcggggtcc ggtcagtcct cgccccggac gatgttcgac
      121 tcctgacccg attgcggtgc gcggacggtg ctgccgtcct ccacggcggg tacgcaggtg
      181 cgcatcacgc ctctgctccg caggcggcgg gccttcgacc agcctgtctc cagccgccgg
      241 acggcgggtt tgccgtcggt gtccgtggtc acggggcatc atcttccttc tggttccgct
      301 tctggtgcgc tcgcccctgc gggtccccgg acggggaccc gtgaaaccca ggggccgtgc
      361 gggccgcgcg gctcagccgc cgcccaccgg gatctcgctc cacacctgct tgcccccgct
      421 gaccggcagc gtcccccagg tcgccgacat cgcctcgacc aggaggatgc cgcgtccgcc
      481 ggtggcctcc cagccgatgc tggtcggctt gaccggcgtg cgcggcgagg cgtcggcgac
      541 ggccacgcgc agccgtccgc cgatcagggt gaggtcgagc cgtaccttgc cgtcggtgtg
      601 caccagggcg ttggtgacca gctcggagac gatcaggagc actccgtcga tgtcgtcgtc
      661 cggtacgccc caggtgcgca gggtgcgccg ggtgaagcgg cgggcgtgcc gcacggcctc
      721 gggcagccgc cacaccgacc agctctcgcg cagcgggcgc agggccattc cgtcgtagcg
      781 caccagcagc agggccacgt cgtcgttgcg gcgggcgttg ccgagcaggg cgtcggcgac
      841 gagtccgagg tggtcggggg cggagacggc cagcgcgtgc gcgaaccggt ccatgccctc
      901 gtcgatgtcg gactccggcg tctccaccag gccgtccgtg gtgagggcga tcagcgtgcc
      961 gggccgcagc cgcagcgggc tcatcgggaa gtcggcctgg gtcaccacgc cgagcggcgg
     1021 gccgccctcc acctccgcga tctcggtgct gccgtcggga tggcgcagca ccggtggcag
     1081 gtgccccgcg cgcacgcacc aggcggagcc ctcctccatg tcgaggtcga cgtagacgca
     1141 ggtggcgaag aggtcggtct ccatgcccgt cagcagccgg ttggcgtggg agaccacgac
     1201 gtccggcggg tggccctcga ccgcgtaggc gcgcagggcg gtgcgcatct ggcccatgag
     1261 ggtggccgcg ccggcgctgt ggccctggac gtcgccgatg acgagggcga cgtggtggtc
     1321 gggcagcggg atcacgtcgt accagtcgcc gcccagctcc aggcccgccg tgctgggcag
     1381 gtagcgggcg acggcgaccg cgccgggcag cttgggcagg cggcgcggca gcagctggcg
     1441 ctggagcatg ccgaccagct cgtgctcggc gtcgaaggcg tgggcgcgca tcagggcctg
     1501 cccggccagg cccgcggagg cggtgagcag ggcccgttcg tcggggccga agtcgtgcgg
     1561 ggtgtcccag ccgatcaggc aggcaccggc catgcgtccg ccggcgggca gcggcagcac
     1621 ggcgaggccg ccggggccga cgtcggcgag ggcgggctcc aggtccccgg tgccggcggg
     1681 ccagatccgg gcgcggccct cgcgcagcgc ggcggccagg gtcggcatgg cccgtaccgg
     1741 cgcgtccggc cactcggtgc gccactccag gcgccacagt tcgggccagg actcggggtc
     1801 gggcgggtcg aggacggtga cgacgagccg gtcgttctcc agctcggcca gcgcgatccg
     1861 gtcggcccgc agcggcctgc gcagggcggc gacgacggcc tggctgacgt cgcggaccgt
     1921 cccggcggtg gccagcgcgg cggccagccg ctggacgcgg gcgacgtcgg tcacgtccgg
     1981 acgcagggtg gaggcgtcgg cgacggtgcc gaccagaagg gccggccggc cctcgccgcc
     2041 gggcagcagg cgcccgctga gccgcagcca cttcggcggg ccggtgggct ggagcacccg
     2101 gaactccagc tcgcgctcgc cgatggtcat gtggtcggac tcggtcaccg acatcaggga
     2161 cggcaggtcc tccggcacgg tgaggccgag cagcgtctcg accttgccgt cgaactcgcc
     2221 gggggccagt ccgaacagcc gcaggatgtc gtcgccgacc tccacccggc cggagtccat
     2281 ggtcagggtg aaggcgtccg gctggaggtc accggtctcg gcacgggcgg cggtctcggc
     2341 cggggcgggg caggtcatcg cctccgcgat cgcctccagg cacgtacggt cgtcggtgtc
     2401 gaacccgtcc gggcgctcgg tcagggcgag gaagcagccg ccgccgtccc cgcgcacggg
     2461 caggacggcg agcgagaagc cgctcgacgg cacatgccgt gactccgccg atccggcgaa
     2521 ctcctccggc ccgatccaca ccgcctcgcc ggcgcggtgg gcgtcggcga ccggggaacc
     2581 gccggacgcg gggtagctgt cgcgtacgcc gtacagcgag cggggcactc cggccgactc
     2641 gaccaggcag agcagctcgc gatcgtcgcc cggcgcgtag agcgcggcga aggaggcgcc
     2701 cgcgaagacc agcgcctgct cgaggattac gcgcagccgc tcctgcggca ccggtccggc
     2761 cacgatcgcg ttcagggcgc cctcggcacg cagcgtcctc ggtccgcgtt ccgcagcgtc
     2821 ctctccggcc acctcgccat tacagcgctt gtgaggcatc cgcgcagccc ctggggaccg
     2881 gggagcggcg atcaggggca ctccggggct cgcggacggg cgcttcgcgc cgccggacgg
     2941 gtgcgggccg ggccgggacc tgccggcggc caggaggtgg tggcggacac gcaccgctgc
     3001 ccgcgggccg tgaaccagtg cggcgggcgg tgcggccggg gcgcagaccg gccgcaccga
     3061 gccgacgtgg cgtcagcccg tcagcccgtc agcccgtcag cccgtcagcc ccgagccgtc
     3121 cctaccgccg acgggtgcac cgtcacccgc gtcacccgcg tcacctgtgt cacctttgtc
     3181 acctttgtca cccgcaccag cgccgccgtc gcccgcgtcg cccgcacctc ccgcatcacc
     3241 ctcctcgccg gcacctgcgc cggcaccgcc cgcgtctccg gcacccgcgc cgccgtcctc
     3301 gcccccgagg gtggcgccga ccgccgccag ggccgtggtg accggctgga agaaggtctc
     3361 gccgccgacc gtgcagtccc cgctgccgcc ggaggtcagg ccgatcgcga ggccgtcccg
     3421 cgtgaagagg gagccgccgc tgtcgccggg ctcggcgcag acgtcggtct gtatgaggcc
     3481 ggtgaccgtg ccctcgggat agttgacggt ggcgtccagg ccgagcacct gcccgtcggc
     3541 cagtccggtc gtactgccca tgcggaagac ctcctggccg accgccgcct cggcggcccc
     3601 gctgatcggc agggtctggt cgccgaggtc gacctcgctc ggcgcctcgg tcgccgggtc
     3661 gtcgtacctg acgagcgcga agtcgccctc gccggggaag accgcctggt cgacggtggc
     3721 gatcggctgt ccgccctgtg cgtcggacca ctggtcggcc gccaccccgc agtgaccggc
     3781 cgtcaggaag gcgggcgagc cgtcgcccgc ggtgacgttg aacccgagtg agcagcgcgc
     3841 tccgccgccg aagatcgcgt cgccgcccga cgcgaaggtc ttgaaggtgc cggcggactt
     3901 cctgaccgtc gccatgccgg acccgaggcc gtcgacggtg gactccagcc ggtcccaccg
     3961 gtcgccggtg acggtgctgt cggcggtcac caggatcttg ttggtccgcg ggtcgatcgc
     4021 ccacgcggtc ccggggatgc cggcctcggc cttcagggtc tgcgcgccgc cgcgcagctc
     4081 gcccatgctg ttgtcgacct cgcggacctt cgcacccgcc ttctcggcct gcacgaccac
     4141 ctggttgttg tcgccgggga cgacgttgac gaccagttgc cgggcgccgg agtcgtagta
     4201 ggagccggcg aagctgtcgc cgagcaggcc ggcgagccgg gcggcgaggt ccgacgcgtc
     4261 cgccgccttg agcgtcctgg gtgccgcggc ggcatcgtcc gaggagccgc cgtcctgcga
     4321 ggcgttcgcg ttcggcagca ggatcgcggc cgcgccgagc gccaccacac cgcccgccgc
     4381 catcgcggcc ctgcgcttgg ggattcgctt gtgactcaac ctgctcgacc tcctgggacc
     4441 ggggttgatg cccgccggtc cggcagctgt tgggggcgcc tggacggctg ttggtacgca
     4501 cggaccgggc ggggtgttca gccgggccct cgcgccgccc ccgatcggca ccctccgcat
     4561 ccggagcgcg acgcaccgtt gcgatcacgg agcggaatga ctgcttcagc gaatctgcac
     4621 atcgaatgcc caacccggtc actcccgttg gcgcatctgc acaagcccgc ggcggcccgt
     4681 acgcctttac ggccgtagtg ccccaatcgc ctcggccggg gcaaggggcc gcacgagccg
     4741 atctcgcgca ccgtgtgaag aagtggccgc gaaggagtgc gcgcccctgc acgcttgggc
     4801 ccgcaggcct cgcaagtgtg ctggtgagag gggtgtttga ttggaagccc ggaccggccg
     4861 cgtgctttga tccatcgcac cgcgggggcc gcggagggct ccggaaaagg gcgcccggcg
     4921 cccgcggtcg cggccgtcat ctgtccccag agggggccgc tccccccttg tgaaatggct
     4981 atacgaaggg aagttccatc atgaactcca ccccccaggt tgagaccgtc gagatctccg
     5041 acgccgacct cgacaacgtc tccggcggcc tgaacgtgaa cgccgtcggc accgtcaccg
     5101 gcctggtgga cggcatcgcc ccggtctccg gcctgctcaa caccgccgtc ggcaccgtcg
     5161 agggtgtcac cggcctgaac acggccccgg tcacgggcct ggtcgccggt ctctgatcgc
     5221 gcccttgcgt cgctgagtcc cggagccgtc caggctccgg gacttttcgg ccgttctccc
     5281 tccggccgtg atcgtccccc ggccgttctc accaagccct ggatacgtca gccgtgcagt
     5341 tccgccaaca ggccctcgca aaactccagt cgccggagga gctcgatctc ccggtgcgtt
     5401 tcgcccgtcc ccagggctgg ctggtgctgt ccgtgacgct gatcgccatg gccgccgcgt
     5461 ccgtgtgggc ggtgggcggc tcggtgacct ccacggtgtc cgcgcccgcc gtcctcaccc
     5521 acgggcaggg cagttacctc ctgcaaagcc ccgtctccgg gcaggtcacc gcggtcctcg
     5581 cccgtccggg gcagcggctg gccgccgacg ccccggtact gaaggtccgc accgcgaagg
     5641 gcgagacggt ggtccgcacg gtggacgccg gccgggtcag cgcactcgcc gccaccgtcg
     5701 ggcagatcat cgccaccggc gcgaacgtcg cgtccgtcga gaaggtcgcc cacgccggcg
     5761 acccgctcta cgccaccgtc tacgtccccg cggagaacgc cgccgccatc cccgcccacg
     5821 cctcggtcga cctgaccgtc cagtcggtgc cgacgcagca gtacggcgtc ctgcacgggg
     5881 aggtgaagtc cgtggaccgc tcggcccagt cggcgcagac gatcggcgcg ttcctcgggg
     5941 acagcgcgct cggcgagcag ttcaccgagg acggcaggcc ggtggccgtg acggtgcggc
     6001 tggcgacctc gaagtccacg aagagcggct acgcgtggtc ctcggccgac gggccgccgt
     6061 tcgaactgac ctccatgacc ctggcctcgg gctcgatccg gctggccgac cagcgtcccg
     6121 tcgattggct gctgccgtga gcaccgcaca ggagacccgg ggcaggcgcc gtgccgcccc
     6181 gccgaggcgc agcgtgccga agagccgcgc gaggaccgtc cgcacgccca cggtgctcca
     6241 gatggaggcc gtggagtgcg gtgccgcctc cctcgccatg gtgctgggac actacggccg
     6301 ccatgtcccc ctggaggagc tgcggatcgc ctgcggtgtc tcccgcgacg ggtcccgggc
     6361 gagcaacctg ctgaaggccg cgcggagtta cgggttcacc gccaagggca tgcagatgga
     6421 cctggccgcc ctcgccgagg tgacggcacc ggccatcctc ttctgggagt tcaaccacta
     6481 cgtcgtctac gacggcatgg gccgccggtt cgggcggcgc ggggtgttca tcaacgaccc
     6541 gggcaaggga cgcaggttcg tgtccctgga ggatttcgac gggtccttca ccggtgtcgt
     6601 gctgaccatg gagcccggtg acggcttcac ccgcggcggc cgcaagcccg gtgtgctcgg
     6661 tgcgatgccc gcccggctgc gcggaaccgc gggcacgctg cccgccgcgg tgctggcgag
     6721 cctgctcctg gtggcggtcg gcgcggcggt gcccgcgctc agccgcacct acatcgacat
     6781 gttcctcatc ggtgggcaga cctcgctgct cggcgtgctg ttcgcgtcga tgggcgcctg
     6841 tgtgctgctc acgatggtgc tgacctggct ccagcaggcc aacctgctgc acgggcgcat
     6901 catctcctcc accctctcca gcgcccgctt cctgcggcac ctgctgcggc tgccggtgac
     6961 cttcttctcc cagcgcagcc ccgccgacct ggtgcagcgg ctccagtcca acgacgccgt
     7021 cgccgagacg ctggcccgcg acctcgccgc ggcgggcgtg gacgcgatcg tggtcgtcct
     7081 gtacgccgtg ctgctgtaca cgtacgaccc gcagctcacc ttcgtcggca tcggtgtggc
     7141 gctgctcaac atcctggcga tgcgggtcgt catccggctg cgcgcgaccc gtacggccaa
     7201 gctgcgggcg gacacggcgc ggctgaccaa caccgcctac accggcctcc agctgatcga
     7261 gacgatgaag gcgaccggcg gcgaggacgg ctacttccgc aagtgggccg gccagcacgc
     7321 caccacgctg gaggagcagc agcggctcgg ggtgcccagt gcctggctgg gcgtggtcgc
     7381 gccgacgctg gcgacgctga acagcgggct gatcctgtgg atcggcggca tgcgcgcggt
     7441 cgagggccac atctcggtcg ggctgctggt cgccttccag gcgctggtgg tccgcttcac
     7501 cgcgccgctg acccggctga acggtgtcgc gggccgcatc caggacttcg cggccgacgt
     7561 ggcccgcctc aaggacgtgg agaacttccg ggcggatccg ctctacgacc gccccggtga
     7621 cggcgactcc acccgccggc tgcgcgggca cgtggagctg cagaacgtct ccttcggcta
     7681 caacccgctc gacaagccgc tgctgtccgg tttcgacctg accgtggggc cggggcagca
     7741 ggtggccctg gtcggcggtt cgggcagcgg caagtcgacg gtgtcgcggc tgatctcggg
     7801 cctgtacgcg ccctgggacg gcgtgatccg catcgacggg cagcggctcg acgacatccc
     7861 gcgcggggcg ctggcgtcct ccgtctcctt cgtcgaccag gacgtgttcc tgttcgaggg
     7921 ctcggtgcgc gacaacgtgg ccctgtggga cccgtcgatc cccgacgacg ccgtggtgga
     7981 ggcgctgaag gacgccgcgc tgtacgacgt ggtgacgcgc aggccgggcg ggctccacag
     8041 cccggtggag caggacggcc gcaacttctc cggcgggcag cgccagcgcc tggagatcgc
     8101 gcgggccttg gtgcgccgcc ccagcatcct cgtcctggac gaggtgacca gcgcgctgga
     8161 cgcggagacc gagctggtgg tgatggacaa cctgcgccgg cgcggctgcg cctgcgtggt
     8221 gatcgcgcac cggctcagca cggtgcggga cagcgacgag atcgtcgtcc tcgaccacgg
     8281 cacggtcgtg gagcgcgggc ggcacgagga gctgctggcg cgcggtggcg cgtacgcggc
     8341 gctggtcagg gagcggtgag atgacaaccg tgcacgaggg gcagggcgac ctggtcctgg
     8401 gggcgctcgg ctcgctgggc acgcgcgtcg actgcgccgg gttcaaccgc ctcgacctgg
     8461 aggggccgca ggtgctgtgg ctcgtggtgt ccggcgcggt ggacctgttc gcggtcgacg
     8521 ccggggagca gggccactgg caccacctgg gacgcctggc ggcgggctcg gtactgctgg
     8581 gaccggtcgc cgggccgcag cacacgctgg tggcacgccc gctgcgggac tgcgtggtgc
     8641 accggatcgg gctgcgcgag ctgtaccagc cggcgcccac ccagacgtgg tcgtacgacg
     8701 cgtacggcaa cccccagtac gtgccgccga cgacgagtcc gctggagtac gccctggccc
     8761 tcggcgtggg acgcggcctg accgtcctct tccaggcgcc gatggccacg gagcgggccg
     8821 gcgcacccac ggacgacgac gtgttctgga tgcaggtgcc gccgggcagc gtgcagtacg
     8881 gggcggtgta cggcgaggag gcggccgccg acctgctgat ggacccggcg ctgtggcaga
     8941 gcatggtcga ccagcagtac cggctgctga ccacccttga ccggtggatc gaacagctgg
     9001 agcgcaccca cgagacccgc acggcggccg gtatcaaggc cggtgaggcg gtgcgcgcgc
     9061 gggccgaccg gacgctgctg gcctccatcg gcaagcgctc ggcgcagcgc accacggccg
     9121 ccgacgccga cgccacgtac gcggcgtgcg ggctggtcgc ccgcgccgcc gggattccgc
     9181 tcgccgagac gtccccgggc ggcaccgaga gcgaccggct ggacccggtg gagcggatcg
     9241 cgctcgcctc gcgggtgcgg accaggtcgg tgcggctggc ggaccgctgg tggcgggagg
     9301 acgtggggcc gctggtcggg caccgcaccc tgtcgggggc gccggtggct ctgctgtggc
     9361 ggcgcggcgg ctatgtagcc gtgcatccgg cgaccggtcg ggagacgccc gtggagcggg
     9421 cgaacgccgg ggagttcgaa ccgcgcgcgg tgatgttcta ccgcccgctg ccggagcggc
     9481 ggccgagtcc gctcgggctg ctccggttct gtctggcggg cacccaccgg gatctgacgt
     9541 cgctgctgct cgccgggctg gtgacggtgg cgctcggcgc gctggtgccg atcgcgacgg
     9601 gccgggtgct cggcgagttc gtgccgaagg cgcagaccgg gctgatcgtg caggtgtgtc
     9661 tcgcggtgat gctgagcagc gtcgtcgcgg cggccttcat gctgctgcag aacctcacca
     9721 tcctgcgtct ggagggccgg atcgaggcca ccctccagcc cgccgtgtgg gaccgcctgc
     9781 tgcggctgcc gacgaagttc ttcaccgagc gctccaccgg cgaactggcg agcgcggcca
     9841 tgggcatcag cgcgatccgc agactgctcg cgggggtcgg cccgaccgtg gcccagtcgg
     9901 tgaccgtcgg ggcgatgaac ctcggtctgc tgctctggta cagcgtgccg atggcgttcg
     9961 ccgcgatcgg catgctggtg gtcgtcgccg gggtgttcct cgggctcggg ctgtggcagg
    10021 tgcgctggca gcggcggctg gtcaaactca ccaacaagct gaacaaccag gcgttccaga
    10081 cgctgcgcgg gctgccgaag ctgcgggtgg cggcagccga gaactacgcc tacgcggcgt
    10141 gggcggagcg gttcgcgcac agccgggagc tgcagcagcg ggcgggccgg atcaagaacc
    10201 tgaacgcggt gctcgg
//
