LOCUS       NZ_BMVL01000037        12079 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence37, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000037
VERSION     NZ_BMVL01000037.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 12079)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 12079
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12079
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            complement(<1..4609)
                     /locus_tag="IE257_RS37465"
     CDS             complement(<1..4609)
                     /NRPS_PKS="Domain: Condensation_LCL (1-300). E-value:
                     1.5e-111. Score: 364.2. Matches aSDomain:
                     nrpspksdomains_IE257_RS37465_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (470-858). E-value:
                     2.2e-107. Score: 351.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS37465_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (964-1032). E-value: 1.1e-27. Score:
                     88.0. Matches aSDomain: nrpspksdomains_IE257_RS37465_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1046-1348). E-value:
                     2.4e-113. Score: 370.0. Matches aSDomain:
                     nrpspksdomains_IE257_RS37465_Condensation_LCL.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="IE257_RS37465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_189974563.1"
                     /sec_met_domain="AMP-binding (E-value: 5.7e-118, bitscore:
                     381.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.6e-18, bitscore:
                     52.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.1e-71, bitscore:
                     227.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPLSFAQRRLWFIGQLDGPNARYNLPVVLRLSGRPDRKALDTAL
                     RDVIGRHEVLRTLYAVTDGEPHQSIVKLDELEWELTTAEVAPAHLDAAVAAAAAYAFDL
                     SQEVPIRAWLYTTGPDAHTLVLTTHHIAGDGWSMRVLARDLSTAYAARTTGRAPEWDPL
                     PVQYADYALWQRELLGDENDPESRMARQVGFWRGALAGVPDELPLPFDRPRPTVGSYRG
                     HRVPLEVPAELHARLARLALAEGLTPFMVLRSALAVLLSRLGAGTDIPIGSAVAGRADS
                     ALDDLVGFFVNTLAIRHDLSGDPSFRDLLARGQERALSAFEHQDVPFEKLVEDLAPGRS
                     MARHPLFQVMFNLQNNAAAVLDLPGLRVEVATTDVHGAKFDLEVDCWETFDTTGLPAGV
                     HGSLTVAADLFDADSAGLLAERLVRVLDQLVADPSAPVAAVEVLDAAERDRLLVEWGGA
                     TPAAPSAPLPELFAAQVARAPEAVAVVSDGVEVSYAELDARANRLARHLADSGVGPGSV
                     VGVCLERGAELVVALLAVTKTGGAYLPLDPEYPAERLAYVLEDAAPVGVVTSAQRAPVL
                     PAGVAPVLVSDPAVAALDDRPLEAVVRSQDAAYVIYTSGSTGRPKGVVVSHGALSAHLS
                     GVGERVPLAAGDRLVAVTTVSFDIAALELFLPLVSGASVVLASRDEVRDPAALTRLVLT
                     SGASVLQAVPSLWRALLEEEGWPAGVRALVGGEALPPELAQRFTDLGVRAVNLYGPTEA
                     TVWATSAEVAGGPVLVGRPFADVGAYVLDGRMRPVPAGVSGELYLYGAQLARGYAGRPG
                     LTAERFVASPFGGAGERLYRTGDLARWTGDGRLECLGRADEQVKVRGFRIEPGEVEAAL
                     SEHESVARAVVIAREDVPGDVRLVAYVVAHDGHTVNAADLRTLAGTRLPSYMVPSAVVV
                     LDELPLTDNGKLNRKALPAPEYTTGAGRGPATLQEELLCGVFAQVLDVEHVGVDEDFFA
                     LGGHSLLATRLVSRIRAVLGTEISLRALFETPTVAGLASRLADADTARVALVAGERPER
                     VPLSYAQRRMWFIGQLEGPSPTYNIPVSLRLRGAVDQQALNAAFCDVLARHELLRTVFT
                     TAEDGEPYQRIIAAGELEAELSVVHVAPEDLDDAVAGAARHLFDLATEIPIRARLFTTA
                     ADEHVLAVVVHHIAGDGWSWAPLARDLSAAYAARSAGLAPEWAPLPVQYADYALWQREL
                     LGDGDDPESLMSRQVAYWRARLAGAPEELALPVDRVRPAMASNRGHEVPVRVPAPLHAA
                     LTRVARAEGVTMSMVLQSALVVLLSRLGAGVDVPIGSANAGRTDTSLEDLVGFFVNALV
                     TRADLSGDPSFREVLGRVRETNLSAFENQDVPFEKLVEELAPARVMGRHPLIQTMFTMQ
                     NNARAVLDLPGAVAGTDPDGVAAETATAAAARFDLDVLLGEVFDASGAPAGVSGSVIGA
                     ADLFEAESVGRIAERLVRVLELVGADPGIPLSGVDVLSAEERGRVVTEWNATGADFGSG
                     LVPGLFGARVVGAPDA"
     source          1..12079
                     /culture_collection="JCM:4726"
                     /db_xref="taxon:1895"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces avidinii"
                     /strain="JCM 4726"
                     /submitter_seqid="sequence37"
                     /type_material="type strain of Streptomyces avidinii"
     cand_cluster    1..12079
                     /SMILES="NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12079
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>12077](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..>12077)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       complement(407..526)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0017"
                     /evalue="4.50E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE257_RS37465"
                     /protein_end="1401"
                     /protein_start="1361"
                     /score="64.1"
                     /tool="antismash"
                     /translation="RETNLSAFENQDVPFEKLVEELAPARVMGRHPLIQTMFTM"
     aSDomain        complement(566..1471)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37465_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.40E-113"
                     /label="IE257_RS37465_Condensation_LCL.2"
                     /locus_tag="IE257_RS37465"
                     /protein_end="1348"
                     /protein_start="1046"
                     /score="370.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAGDG"
                     /tool="antismash"
                     /translation="ERVPLSYAQRRMWFIGQLEGPSPTYNIPVSLRLRGAVDQQALNAA
                     FCDVLARHELLRTVFTTAEDGEPYQRIIAAGELEAELSVVHVAPEDLDDAVAGAARHLF
                     DLATEIPIRARLFTTAADEHVLAVVVHHIAGDGWSWAPLARDLSAAYAARSAGLAPEWA
                     PLPVQYADYALWQRELLGDGDDPESLMSRQVAYWRARLAGAPEELALPVDRVRPAMASN
                     RGHEVPVRVPAPLHAALTRVARAEGVTMSMVLQSALVVLLSRLGAGVDVPIGSANAGRT
                     DTSLEDLVGFFVNALVTRADL"
     CDS_motif       complement(575..664)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0016"
                     /evalue="2.50E-10"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE257_RS37465"
                     /protein_end="1345"
                     /protein_start="1315"
                     /score="32.8"
                     /tool="antismash"
                     /translation="DVPIGSANAGRTDTSLEDLVGFFVNALVTR"
     CDS_motif       complement(932..970)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0015"
                     /evalue="2.80E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="IE257_RS37465"
                     /protein_end="1226"
                     /protein_start="1213"
                     /score="19.7"
                     /tool="antismash"
                     /translation="QYADYALWQRELL"
     CDS_motif       complement(1019..1084)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0014"
                     /evalue="3.30E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE257_RS37465"
                     /protein_end="1197"
                     /protein_start="1175"
                     /score="32.4"
                     /tool="antismash"
                     /translation="VHHIAGDGWSWAPLARDLSAAY"
     CDS_motif       complement(1292..1405)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0013"
                     /evalue="1.20E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE257_RS37465"
                     /protein_end="1106"
                     /protein_start="1068"
                     /score="53.0"
                     /tool="antismash"
                     /translation="PTYNIPVSLRLRGAVDQQALNAAFCDVLARHELLRTVF"
     CDS_motif       complement(1427..1456)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0012"
                     /evalue="9.20E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="IE257_RS37465"
                     /protein_end="1061"
                     /protein_start="1051"
                     /score="8.8"
                     /tool="antismash"
                     /translation="SYAQRRMWFI"
     aSDomain        complement(1514..1717)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37465_PCP.1"
                     /evalue="1.10E-27"
                     /label="IE257_RS37465_PCP.1"
                     /locus_tag="IE257_RS37465"
                     /protein_end="1032"
                     /protein_start="964"
                     /score="88.0"
                     /tool="antismash"
                     /translation="EELLCGVFAQVLDVEHVGVDEDFFALGGHSLLATRLVSRIRAVLG
                     TEISLRALFETPTVAGLASRLAD"
     aSModule        complement(1514..4606)
                     /complete
                     /domains="nrpspksdomains_IE257_RS37465_Condensation_LCL.1"
                     /domains="nrpspksdomains_IE257_RS37465_AMP-binding.1"
                     /domains="nrpspksdomains_IE257_RS37465_PCP.1"
                     /locus_tags="IE257_RS37465"
                     /monomer_pairings="Gly -> Gly"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2006..2071)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0011"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS37465"
                     /protein_end="868"
                     /protein_start="846"
                     /score="36.6"
                     /tool="antismash"
                     /translation="CLGRADEQVKVRGFRIEPGEVE"
     aSDomain        complement(2036..3199)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37465_AMP-binding.1"
                     /evalue="2.20E-107"
                     /label="IE257_RS37465_AMP-binding.1"
                     /locus_tag="IE257_RS37465"
                     /protein_end="858"
                     /protein_start="470"
                     /score="351.1"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="FAAQVARAPEAVAVVSDGVEVSYAELDARANRLARHLADSGVGPG
                     SVVGVCLERGAELVVALLAVTKTGGAYLPLDPEYPAERLAYVLEDAAPVGVVTSAQRAP
                     VLPAGVAPVLVSDPAVAALDDRPLEAVVRSQDAAYVIYTSGSTGRPKGVVVSHGALSAH
                     LSGVGERVPLAAGDRLVAVTTVSFDIAALELFLPLVSGASVVLASRDEVRDPAALTRLV
                     LTSGASVLQAVPSLWRALLEEEGWPAGVRALVGGEALPPELAQRFTDLGVRAVNLYGPT
                     EATVWATSAEVAGGPVLVGRPFADVGAYVLDGRMRPVPAGVSGELYLYGAQLARGYAGR
                     PGLTAERFVASPFGGAGERLYRTGDLARWTGDGRLECLGRADEQVKVR"
     CDS_motif       complement(2156..2245)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0010"
                     /evalue="5.20E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS37465"
                     /protein_end="818"
                     /protein_start="788"
                     /score="44.3"
                     /tool="antismash"
                     /translation="PAGVSGELYLYGAQLARGYAGRPGLTAERF"
     CDS_motif       complement(2729..2788)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0009"
                     /evalue="4.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS37465"
                     /protein_end="627"
                     /protein_start="607"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVVVSH"
     CDS_motif       complement(2972..3013)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0008"
                     /evalue="5.80E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS37465"
                     /protein_end="546"
                     /protein_start="532"
                     /score="13.3"
                     /tool="antismash"
                     /translation="LAVTKTGGAYLPLD"
     CDS_motif       complement(3341..3379)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0007"
                     /evalue="4.30E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="IE257_RS37465"
                     /protein_end="423"
                     /protein_start="410"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="DADSAGLLAERLV"
     CDS_motif       complement(3551..3670)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0006"
                     /evalue="2.60E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE257_RS37465"
                     /protein_end="353"
                     /protein_start="313"
                     /score="71.3"
                     /tool="antismash"
                     /translation="QERALSAFEHQDVPFEKLVEDLAPGRSMARHPLFQVMFNL"
     aSDomain        complement(3710..4606)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37465_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.50E-111"
                     /label="IE257_RS37465_Condensation_LCL.1"
                     /locus_tag="IE257_RS37465"
                     /protein_end="300"
                     /protein_start="1"
                     /score="364.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAGDG"
                     /tool="antismash"
                     /translation="VPLSFAQRRLWFIGQLDGPNARYNLPVVLRLSGRPDRKALDTALR
                     DVIGRHEVLRTLYAVTDGEPHQSIVKLDELEWELTTAEVAPAHLDAAVAAAAAYAFDLS
                     QEVPIRAWLYTTGPDAHTLVLTTHHIAGDGWSMRVLARDLSTAYAARTTGRAPEWDPLP
                     VQYADYALWQRELLGDENDPESRMARQVGFWRGALAGVPDELPLPFDRPRPTVGSYRGH
                     RVPLEVPAELHARLARLALAEGLTPFMVLRSALAVLLSRLGAGTDIPIGSAVAGRADSA
                     LDDLVGFFVNTLAIRHDL"
     CDS_motif       complement(3719..3808)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0005"
                     /evalue="1.00E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE257_RS37465"
                     /protein_end="297"
                     /protein_start="267"
                     /score="40.4"
                     /tool="antismash"
                     /translation="DIPIGSAVAGRADSALDDLVGFFVNTLAIR"
     CDS_motif       complement(4076..4114)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0004"
                     /evalue="2.80E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="IE257_RS37465"
                     /protein_end="178"
                     /protein_start="165"
                     /score="19.7"
                     /tool="antismash"
                     /translation="QYADYALWQRELL"
     CDS_motif       complement(4163..4225)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0003"
                     /evalue="4.70E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE257_RS37465"
                     /protein_end="149"
                     /protein_start="128"
                     /score="35.1"
                     /tool="antismash"
                     /translation="HHIAGDGWSMRVLARDLSTAY"
     CDS_motif       complement(4433..4540)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0002"
                     /evalue="5.00E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE257_RS37465"
                     /protein_end="59"
                     /protein_start="23"
                     /score="41.4"
                     /tool="antismash"
                     /translation="YNLPVVLRLSGRPDRKALDTALRDVIGRHEVLRTLY"
     CDS_motif       complement(4568..4597)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37465_0001"
                     /evalue="1.40E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="IE257_RS37465"
                     /protein_end="14"
                     /protein_start="4"
                     /score="8.3"
                     /tool="antismash"
                     /translation="SFAQRRLWFI"
     CDS             complement(4609..>12077)
                     /NRPS_PKS="Domain: PCP (236-300). E-value: 3.1e-23. Score:
                     73.7. Matches aSDomain: nrpspksdomains_IE257_RS37470_PCP.1"
                     /NRPS_PKS="Domain: Condensation_Dual (350-639). E-value:
                     1.5e-109. Score: 357.9. Matches aSDomain:
                     nrpspksdomains_IE257_RS37470_Condensation_Dual.1"
                     /NRPS_PKS="Domain: AMP-binding (808-1211). E-value:
                     3.4e-98. Score: 320.9. Matches aSDomain:
                     nrpspksdomains_IE257_RS37470_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1321-1387). E-value: 4.3e-25.
                     Score: 79.7. Matches aSDomain:
                     nrpspksdomains_IE257_RS37470_PCP.2"
                     /NRPS_PKS="Domain: Condensation_Dual (1435-1727). E-value:
                     6.7e-107. Score: 349.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS37470_Condensation_Dual.2"
                     /NRPS_PKS="Domain: AMP-binding (1895-2297). E-value:
                     6.2e-96. Score: 313.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS37470_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2404-2472). E-value: 6.5e-26.
                     Score: 82.3. Matches aSDomain:
                     nrpspksdomains_IE257_RS37470_PCP.3"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /locus_tag="IE257_RS37470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_189974565.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-107, bitscore:
                     346.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.5e-49, bitscore:
                     153.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-17, bitscore:
                     51.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QRRFFEVFDGVELHNLYGPTEASVDVTAWQCRPEQSTGTVPIGAP
                     VANTRLYVLDAGLRPVPVGVAGELYLAGVQLARGYANRPGLTAERFVASPYGTGERLYR
                     TGDVVRWNADGQVEYLGRVDEQVKVRGFRIEPGEVQAVVAAHPQVAQAAVVAREDVSGD
                     KRLVAYVVPVGEGSVQEEDVREFVAGRLPEYMVPSAVVVLDALPLSVNGKLDRKALPAP
                     EYTAGSGRGPANAREEIVCAAFAEVLGLESVGVDDDFFRLGGHSLLAVRLMEVLRGHGV
                     STSVREFFRSPTPAALADSTGAAQVVVPENLIPVDATEITPEMLPLVDLTADEVARIVA
                     TVEGGPANVADVYPLAPLQEGLLFHHLLADGGEDAYVLRAAMEFDTKDRLEAFVEALQL
                     VVDRHDIFRTSFVWEGLREPVQVVWRKAVLPVNEVTLDPATTDPAADLQAIVGSLMDLG
                     RAPLIAVDYARLPGGGWMALARMHHTVRDHTALEVVLSEVRTIVTGRSAQLPAPMPFRN
                     FVAQTRGGVPLVEHERYFARLLGDVTEPTAAYGLLNVRGDGADTVHEVTSFGADLSIRL
                     REAARRIGTSPATLLHVAWARVLAAVSGRDDVVFGTVLYGRMNAGAGADRVPGPFMNTL
                     PVRVLAGRQGVLDAVTAMRNQLAELLEHEHAPLVAAQRASGLVGDTPLFTSFLNYRRNE
                     GQSPEERAGAVMEGTRLLLSRERTNYPLVILVDDNDDGIEVAVDAVAPIDSHTVGAQVR
                     TAVASLVTALEAALDGGPQTALSAVRVLEDDERTRLLTEWNGTAEEVPADSVAGLFGAQ
                     VARTPDAAAIVADGERVSFAELDVRANRIAHHLVAQGIGAESVVGLALPRGAEMITGML
                     AVWKAGAGYLPLDPEQPADRTAFMMKDSSVTLVLTTEEILDDLPAGRIRTVALDGTLTA
                     MQLAAAPSTAPEVVTDPAGLAYVIYTSGSTGRPKGVAVTHGALTNYVSTVPPRIGFTGA
                     GSRYALLQAQVTDLGNTVLFASLVTGGELHILQEGAVTDPAAVSAYLAEHAIDHLKVVP
                     SHLAALSAVAGPTDVLPAKSLVLGGEAAAPGWVRELVAGAGDRAVHNHYGPTETTIGVA
                     TTRLTAELVADGEVPIGRPVGNTRVFVLDDRLEPVPVGVAGGLYVAGAQLARGYVRRAG
                     QTAERFVANPYESGGRMYRTGDLAKWTTDGRLVFLGRADEQVKIRGYRIEPGEVQAAVA
                     AHPLVAQAAVVARQDALGDTSLVAYAVPGDGAETEGFAAQIRQFTAERLPEHLVPSAVV
                     VMDALPLSGNGKLDRKALPAPDFVGLAGSGRGPADAREEIVCAAFAEVLGLERVGVEDD
                     FFELGGHSLVAVRLVEILRVQGVSVSVRTLFDNPTPAGVAASVGAVRIEAPANRIPLGA
                     TEITPEMLSMVDLSEQEIAKVVASVPGGAANVADVYPLAPLQEGLLFHHMLADGGEDAY
                     VMPAVLEFDSRARLDAFSRAVNEVVNRHDIYRTSYVWQGLREPVQVVLRHAELPVTEVT
                     LDPASPDPVAELVDLGGHSMDLSSPPLITLHTAALPGSGGKWLALIRAHHMVRDHTALV
                     VLLTEVQAFVTGHEADLPEPLPYRNFVAQARGGVPQSEHARYFERLLGDIEEPTAPFGL
                     VDVRGDGAALVRSRVAPAPEVDVRLREVARRLGTSPATLLHVVWARVLSAVSHGQDVVF
                     GTVLSGRMNAGEGADRIPGPFINTLPVRVNHDGPGVVAAVSAMRSQLAELLEHEHAPLV
                     VAQRASRVAGGSPLFTTFLNYRRNAGQNLDERWDGELLGTRLVFARERTNFPLALMVDD
                     NGVDIDLSIDAVAPADGVAVGELVRTAAANLVTALEAALEGGPDVPLGAVEVLGEEERR
                     RILGEWNTTGRDLAAATVPELFAAQVARTPEAVAVVAGGGSLTYAELDARANRLARLLT
                     GRGVGPESVVAVALPRGADLVVSLLAVVKAGGAYLPVDLSYPADRIAHMLRDSSATLVL
                     TDGAAGVGAGDLPRLAPWEADEESAGLSGAPLGTGERSAEPGPDHTAYVVYTSGSTGLP
                     KGTAVPHRAVDRLVRRNGFLEPGPGNVVAQLASASFDAATFEIWGALLNGATLAVPAPG
                     ALSVAEVGTFLREHGVDTLWLTAGLFHEVVDQDVSVLAGVRRLLAGGDALSVAHCRRLL
                     AALPSLRLFNGYGPTENTTFTAVHEVLAAELGEDAGSVPIGTPVADTRVYVLDAGLRPV
                     PVGVEGDLYTTGAGLARGYGGQPALTAERFVACPFEPGARMYRTGDRASWTAQGRLLFA
                     GRTDHQVKIRGFRVEPGEVESVVASHPLVVQAAVIAREDTPGQVRLVAYAVADHDAPNE
                     LPSVIQGFLADRLPEYLVPAATVVLDALPLTANGKLDRKALPAPEYRVGEGRGPADSRE
                     AAVSDLFREVLGLDKVGMDDDFFALGGHSLLATRLVTRVREVLGVEIPLRAVFEARTVA
                     GLARRVGTEKSTRPALRPMRNHEES"
     gene            complement(4609..>12079)
                     /locus_tag="IE257_RS37470"
     aSDomain        complement(4660..4863)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37470_PCP.3"
                     /evalue="6.50E-26"
                     /label="IE257_RS37470_PCP.3"
                     /locus_tag="IE257_RS37470"
                     /protein_end="2472"
                     /protein_start="2404"
                     /score="82.3"
                     /tool="antismash"
                     /translation="EAAVSDLFREVLGLDKVGMDDDFFALGGHSLLATRLVTRVREVLG
                     VEIPLRAVFEARTVAGLARRVGT"
     aSModule        complement(4660..7770)
                     /complete
                     /domains="nrpspksdomains_IE257_RS37470_Condensation_Dual.2"
                     /domains="nrpspksdomains_IE257_RS37470_AMP-binding.2"
                     /domains="nrpspksdomains_IE257_RS37470_PCP.3"
                     /locus_tags="IE257_RS37470"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(4912..4938)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0030"
                     /evalue="2.10E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="IE257_RS37470"
                     /protein_end="2388"
                     /protein_start="2379"
                     /score="4.8"
                     /tool="antismash"
                     /translation="GKLDRKALP"
     CDS_motif       complement(5155..5220)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0029"
                     /evalue="3.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS37470"
                     /protein_end="2307"
                     /protein_start="2285"
                     /score="35.1"
                     /tool="antismash"
                     /translation="FAGRTDHQVKIRGFRVEPGEVE"
     aSDomain        complement(5185..6390)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37470_AMP-binding.2"
                     /evalue="6.20E-96"
                     /label="IE257_RS37470_AMP-binding.2"
                     /locus_tag="IE257_RS37470"
                     /protein_end="2297"
                     /protein_start="1895"
                     /score="313.4"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FAAQVARTPEAVAVVAGGGSLTYAELDARANRLARLLTGRGVGPE
                     SVVAVALPRGADLVVSLLAVVKAGGAYLPVDLSYPADRIAHMLRDSSATLVLTDGAAGV
                     GAGDLPRLAPWEADEESAGLSGAPLGTGERSAEPGPDHTAYVVYTSGSTGLPKGTAVPH
                     RAVDRLVRRNGFLEPGPGNVVAQLASASFDAATFEIWGALLNGATLAVPAPGALSVAEV
                     GTFLREHGVDTLWLTAGLFHEVVDQDVSVLAGVRRLLAGGDALSVAHCRRLLAALPSLR
                     LFNGYGPTENTTFTAVHEVLAAELGEDAGSVPIGTPVADTRVYVLDAGLRPVPVGVEGD
                     LYTTGAGLARGYGGQPALTAERFVACPFEPGARMYRTGDRASWTAQGRLLFAGRTDHQV
                     KIR"
     CDS_motif       complement(5302..5391)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0028"
                     /evalue="8.00E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS37470"
                     /protein_end="2258"
                     /protein_start="2228"
                     /score="37.4"
                     /tool="antismash"
                     /translation="PVGVEGDLYTTGAGLARGYGGQPALTAERF"
     CDS_motif       complement(5512..5535)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0027"
                     /evalue="7.30E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="IE257_RS37470"
                     /protein_end="2188"
                     /protein_start="2180"
                     /score="3.5"
                     /tool="antismash"
                     /translation="YGPTENTT"
     CDS_motif       complement(5902..5961)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0026"
                     /evalue="3.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS37470"
                     /protein_end="2058"
                     /protein_start="2038"
                     /score="25.7"
                     /tool="antismash"
                     /translation="AYVVYTSGSTGLPKGTAVPH"
     CDS_motif       complement(6163..6204)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0025"
                     /evalue="2.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1971"
                     /protein_start="1957"
                     /score="14.6"
                     /tool="antismash"
                     /translation="LAVVKAGGAYLPVD"
     CDS_motif       complement(6781..6846)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0024"
                     /evalue="7.20E-07"
                     /label="C67_dual_14fromHMM"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1765"
                     /protein_start="1743"
                     /score="21.9"
                     /tool="antismash"
                     /translation="LAELLEHEHAPLVVAQRASRVA"
     aSDomain        complement(6895..7770)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37470_Condensation_Dual.
                     2"
                     /domain_subtypes="Condensation_Dual"
                     /evalue="6.70E-107"
                     /label="IE257_RS37470_Condensation_Dual.2"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1727"
                     /protein_start="1435"
                     /score="349.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHMVRDH"
                     /tool="antismash"
                     /translation="DVYPLAPLQEGLLFHHMLADGGEDAYVMPAVLEFDSRARLDAFSR
                     AVNEVVNRHDIYRTSYVWQGLREPVQVVLRHAELPVTEVTLDPASPDPVAELVDLGGHS
                     MDLSSPPLITLHTAALPGSGGKWLALIRAHHMVRDHTALVVLLTEVQAFVTGHEADLPE
                     PLPYRNFVAQARGGVPQSEHARYFERLLGDIEEPTAPFGLVDVRGDGAALVRSRVAPAP
                     EVDVRLREVARRLGTSPATLLHVVWARVLSAVSHGQDVVFGTVLSGRMNAGEGADRIPG
                     PFINTLPVRVN"
     CDS_motif       complement(6901..6996)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0023"
                     /evalue="6.50E-13"
                     /label="C5_dual_260-291"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1725"
                     /protein_start="1693"
                     /score="41.0"
                     /tool="antismash"
                     /translation="DVVFGTVLSGRMNAGEGADRIPGPFINTLPVR"
     CDS_motif       complement(7006..7065)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0022"
                     /evalue="6.80E+00"
                     /label="Cy4"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1690"
                     /protein_start="1670"
                     /score="0.2"
                     /tool="antismash"
                     /translation="GTSPATLLHVVWARVLSAVS"
     CDS_motif       complement(7237..7275)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0021"
                     /evalue="1.50E-04"
                     /label="C4_dual_169-182"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1613"
                     /protein_start="1600"
                     /score="14.6"
                     /tool="antismash"
                     /translation="PYRNFVAQARGGV"
     CDS_motif       complement(7312..7371)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0020"
                     /evalue="1.80E-05"
                     /label="C3_dual_135-156"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1588"
                     /protein_start="1568"
                     /score="17.7"
                     /tool="antismash"
                     /translation="HHMVRDHTALVVLLTEVQAF"
     CDS_motif       complement(7582..7695)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0019"
                     /evalue="3.30E-16"
                     /label="C2_dual_024-063"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1498"
                     /protein_start="1460"
                     /score="51.8"
                     /tool="antismash"
                     /translation="YVMPAVLEFDSRARLDAFSRAVNEVVNRHDIYRTSYVW"
     CDS_motif       complement(7723..7764)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0018"
                     /evalue="1.50E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1451"
                     /protein_start="1437"
                     /score="20.5"
                     /tool="antismash"
                     /translation="YPLAPLQEGLLFHH"
     aSDomain        complement(7915..8112)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37470_PCP.2"
                     /evalue="4.30E-25"
                     /label="IE257_RS37470_PCP.2"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1387"
                     /protein_start="1321"
                     /score="79.7"
                     /tool="antismash"
                     /translation="EEIVCAAFAEVLGLERVGVEDDFFELGGHSLVAVRLVEILRVQGV
                     SVSVRTLFDNPTPAGVAASVG"
     aSModule        complement(7915..11025)
                     /complete
                     /domains="nrpspksdomains_IE257_RS37470_Condensation_Dual.1"
                     /domains="nrpspksdomains_IE257_RS37470_AMP-binding.1"
                     /domains="nrpspksdomains_IE257_RS37470_PCP.2"
                     /locus_tags="IE257_RS37470"
                     /monomer_pairings="Asp -> Asp"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(8167..8193)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0017"
                     /evalue="2.10E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1303"
                     /protein_start="1294"
                     /score="4.8"
                     /tool="antismash"
                     /translation="GKLDRKALP"
     CDS_motif       complement(8416..8478)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0016"
                     /evalue="2.80E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1220"
                     /protein_start="1199"
                     /score="35.4"
                     /tool="antismash"
                     /translation="FLGRADEQVKIRGYRIEPGEV"
     aSDomain        complement(8443..9651)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37470_AMP-binding.1"
                     /evalue="3.40E-98"
                     /label="IE257_RS37470_AMP-binding.1"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1211"
                     /protein_start="808"
                     /score="320.9"
                     /specificity="substrate consensus: Asp"
                     /tool="antismash"
                     /translation="FGAQVARTPDAAAIVADGERVSFAELDVRANRIAHHLVAQGIGAE
                     SVVGLALPRGAEMITGMLAVWKAGAGYLPLDPEQPADRTAFMMKDSSVTLVLTTEEILD
                     DLPAGRIRTVALDGTLTAMQLAAAPSTAPEVVTDPAGLAYVIYTSGSTGRPKGVAVTHG
                     ALTNYVSTVPPRIGFTGAGSRYALLQAQVTDLGNTVLFASLVTGGELHILQEGAVTDPA
                     AVSAYLAEHAIDHLKVVPSHLAALSAVAGPTDVLPAKSLVLGGEAAAPGWVRELVAGAG
                     DRAVHNHYGPTETTIGVATTRLTAELVADGEVPIGRPVGNTRVFVLDDRLEPVPVGVAG
                     GLYVAGAQLARGYVRRAGQTAERFVANPYESGGRMYRTGDLAKWTTDGRLVFLGRADEQ
                     VKIR"
     CDS_motif       complement(8560..8649)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0015"
                     /evalue="2.80E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1172"
                     /protein_start="1142"
                     /score="38.8"
                     /tool="antismash"
                     /translation="PVGVAGGLYVAGAQLARGYVRRAGQTAERF"
     CDS_motif       complement(8764..8787)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0014"
                     /evalue="6.80E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="IE257_RS37470"
                     /protein_end="1104"
                     /protein_start="1096"
                     /score="6.4"
                     /tool="antismash"
                     /translation="YGPTETTI"
     CDS_motif       complement(9166..9225)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0013"
                     /evalue="1.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS37470"
                     /protein_end="970"
                     /protein_start="950"
                     /score="32.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVTH"
     CDS_motif       complement(9424..9465)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0012"
                     /evalue="7.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS37470"
                     /protein_end="884"
                     /protein_start="870"
                     /score="16.0"
                     /tool="antismash"
                     /translation="LAVWKAGAGYLPLD"
     CDS_motif       complement(10018..10110)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0011"
                     /evalue="3.90E-07"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="IE257_RS37470"
                     /protein_end="686"
                     /protein_start="655"
                     /score="22.4"
                     /tool="antismash"
                     /translation="QLAELLEHEHAPLVAAQRASGLVGDTPLFTS"
     aSDomain        complement(10159..11025)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37470_Condensation_Dual.
                     1"
                     /domain_subtypes="Condensation_Dual"
                     /evalue="1.50E-109"
                     /label="IE257_RS37470_Condensation_Dual.1"
                     /locus_tag="IE257_RS37470"
                     /protein_end="639"
                     /protein_start="350"
                     /score="357.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHTVRDH"
                     /tool="antismash"
                     /translation="DVYPLAPLQEGLLFHHLLADGGEDAYVLRAAMEFDTKDRLEAFVE
                     ALQLVVDRHDIFRTSFVWEGLREPVQVVWRKAVLPVNEVTLDPATTDPAADLQAIVGSL
                     MDLGRAPLIAVDYARLPGGGWMALARMHHTVRDHTALEVVLSEVRTIVTGRSAQLPAPM
                     PFRNFVAQTRGGVPLVEHERYFARLLGDVTEPTAAYGLLNVRGDGADTVHEVTSFGADL
                     SIRLREAARRIGTSPATLLHVAWARVLAAVSGRDDVVFGTVLYGRMNAGAGADRVPGPF
                     MNTLPVRV"
     CDS_motif       complement(10162..10257)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0010"
                     /evalue="3.20E-12"
                     /label="C5_dual_260-291"
                     /locus_tag="IE257_RS37470"
                     /protein_end="638"
                     /protein_start="606"
                     /score="38.8"
                     /tool="antismash"
                     /translation="DVVFGTVLYGRMNAGAGADRVPGPFMNTLPVR"
     CDS_motif       complement(10267..10326)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0009"
                     /evalue="1.80E+00"
                     /label="Cy4"
                     /locus_tag="IE257_RS37470"
                     /protein_end="603"
                     /protein_start="583"
                     /score="2.0"
                     /tool="antismash"
                     /translation="GTSPATLLHVAWARVLAAVS"
     CDS_motif       complement(10498..10536)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0008"
                     /evalue="4.20E-04"
                     /label="C4_dual_169-182"
                     /locus_tag="IE257_RS37470"
                     /protein_end="526"
                     /protein_start="513"
                     /score="13.2"
                     /tool="antismash"
                     /translation="PFRNFVAQTRGGV"
     CDS_motif       complement(10573..10635)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0007"
                     /evalue="3.00E-06"
                     /label="C3_dual_135-156"
                     /locus_tag="IE257_RS37470"
                     /protein_end="501"
                     /protein_start="480"
                     /score="20.1"
                     /tool="antismash"
                     /translation="MHHTVRDHTALEVVLSEVRTI"
     CDS_motif       complement(10837..10950)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0006"
                     /evalue="9.80E-17"
                     /label="C2_dual_024-063"
                     /locus_tag="IE257_RS37470"
                     /protein_end="413"
                     /protein_start="375"
                     /score="53.5"
                     /tool="antismash"
                     /translation="YVLRAAMEFDTKDRLEAFVEALQLVVDRHDIFRTSFVW"
     CDS_motif       complement(10978..11019)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0005"
                     /evalue="1.50E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="IE257_RS37470"
                     /protein_end="366"
                     /protein_start="352"
                     /score="20.5"
                     /tool="antismash"
                     /translation="YPLAPLQEGLLFHH"
     aSDomain        complement(11176..11367)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37470_PCP.1"
                     /evalue="3.10E-23"
                     /label="IE257_RS37470_PCP.1"
                     /locus_tag="IE257_RS37470"
                     /protein_end="300"
                     /protein_start="236"
                     /score="73.7"
                     /tool="antismash"
                     /translation="EEIVCAAFAEVLGLESVGVDDDFFRLGGHSLLAVRLMEVLRGHGV
                     STSVREFFRSPTPAALADS"
     CDS_motif       complement(11416..11442)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0004"
                     /evalue="2.10E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="IE257_RS37470"
                     /protein_end="220"
                     /protein_start="211"
                     /score="4.8"
                     /tool="antismash"
                     /translation="GKLDRKALP"
     CDS_motif       complement(11659..11721)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0003"
                     /evalue="6.90E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS37470"
                     /protein_end="139"
                     /protein_start="118"
                     /score="34.2"
                     /tool="antismash"
                     /translation="YLGRVDEQVKVRGFRIEPGEV"
     CDS_motif       complement(11803..11892)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0002"
                     /evalue="3.00E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS37470"
                     /protein_end="91"
                     /protein_start="61"
                     /score="51.5"
                     /tool="antismash"
                     /translation="PVGVAGELYLAGVQLARGYANRPGLTAERF"
     CDS_motif       complement(12004..12027)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37470_0001"
                     /evalue="4.50E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="IE257_RS37470"
                     /protein_end="24"
                     /protein_start="16"
                     /score="4.1"
                     /tool="antismash"
                     /translation="YGPTEASV"
ORIGIN
        1 ccgcatccgg agcccccacc acccgcgccc cgaacaaccc cggcaccaaa cccgaaccga
       61 aatcggcccc cgtcgcgttc cactccgtca cgacccgacc acgctcctcg gcggacagca
      121 cgtccacccc gctcagcggg atccccgggt cggcgcccac cagctccagt acgcgcacca
      181 ggcgctccgc gatccgcccg acgctctccg cctcgaagag gtccgccgcg ccgatcaccg
      241 atccggacac tcccgcggga gcaccggaag cgtcgaacac ctcgcccagc aggacgtcca
      301 gatcgaaccg cgccgcggca gcggtggcgg tctccgcggc caccccgtcc gggtccgtac
      361 cggcgaccgc acccggcagg tccagtacgg cccgcgcgtt gttctgcatc gtgaacatcg
      421 tctggatcag cggatggcgc cccatcacac gcgccggggc cagctcctcg accagcttct
      481 cgaacggcac gtcctggttc tcgaacgcgg acaggttggt ctcgcgtacc cgtcccagca
      541 cttcacggaa gctggggtcg cccgacaggt ccgccctggt gaccagggcg ttcacgaaga
      601 acccgacgag gtcctcgagc gacgtgtcgg tgcgccccgc gttcgccgag ccgatcggta
      661 cgtccacacc cgcgccgagc cgcgacagca ggaccaccag cgccgactgc aggaccatgg
      721 acatcgtcac gccctcggcc cgcgccaccc gcgtcaacgc ggcgtgcagc ggagccggaa
      781 cccggacggg cacctcgtga ccgcggttcg atgccattgc cgggcgcacc cggtccaccg
      841 gcagtgcgag ttcctccggc gctccggcca accgtgcacg ccagtaggcg acctggcgcg
      901 acatcaggct ttcgggatca tcgccgtcgc ccagcagttc gcgctgccac agggcgtagt
      961 cggcgtactg gaccgggagc ggggcccatt cgggcgccag gcccgcggag cgcgcagcgt
     1021 aggccgccga caggtcccgc gccagcgggg cccacgacca gccgtcgccc gcgatgtggt
     1081 ggaccaccac ggccaggacg tgctcgtccg cggcggtggt gaagagccgg gcccggatcg
     1141 ggatctcggt ggccaggtcg aagaggtggc gcgcggcacc ggccacggcg tcgtccagat
     1201 cctccggagc cacgtggacc accgagagct ccgcctccag ctccccggcc gcgatgatcc
     1261 gctggtacgg ctccccgtcc tcggcggtcg tgaacacggt gcgcagcagc tcgtggcggg
     1321 ccaggacgtc gcagaacgcg gcgttcaggg cctgctggtc gacggcaccc cgcaggcgca
     1381 gggagaccgg gatgttgtag gtggggctgg ggccttcgag ctgcccgatg aaccacatgc
     1441 ggcgctgcgc gtacgacagc ggtacccgct cgggacgttc cccggccacg agtgccacgc
     1501 gcgccgtgtc cgcgtcggcc agccgggacg cgaggcccgc caccgtgggc gtctcgaaca
     1561 gtgcccgcag cgagatctcg gtgccgagca ccgcgcggat ccggctgacc agccgggtgg
     1621 cgagcaggga gtgaccgccg agcgcgaaga agtcctcgtc cacgcccacg tgctccacgt
     1681 cgagcacctg cgcgaacacg ccgcacagca gctcctcctg gagcgtggcc ggaccacggc
     1741 cggcgccggt cgtgtactcc ggggcgggca gtgccttccg gttcagcttc ccgttgtccg
     1801 tgagcggcag ctcgtccagc accaccacgg cggacgggac catgtacgag ggcagtcgcg
     1861 tccccgccag tgtgcgcagg tccgccgcgt tcacggtgtg cccgtcgtgg gccaccacgt
     1921 aggccaccag acggacgtcg ccgggcacgt cctcgcgggc gatgaccacg gcccgggcca
     1981 ccgattcgtg ctcggacagt gcggcctcga cctcgccggg ttcgatgcgg aagccgcgga
     2041 ccttgacctg ctcatcggcc cgacccaggc actccagacg cccgtcgccc gtccaccgcg
     2101 cgagatcgcc cgtacggtac aaccgctcac cggccccacc gaacggagaa gccacgaacc
     2161 gctccgccgt caaccccgga cgacccgcat aaccccgagc caactgggca ccgtacaaat
     2221 acagttcgcc cgagacaccc gccggtaccg gccgcatccg gccatccagc acatacgcgc
     2281 ccacatcggc gaacggccgc ccgaccagca ccggaccacc ggcgacctcc gccgacgtcg
     2341 cccacaccgt cgcctcggtc ggaccgtaca ggttcaccgc ccggacaccg agatccgtga
     2401 agcgctgtgc cagctccggc ggcagtgcct caccgcccac cagcgcccgc accccggccg
     2461 gccagccctc ctcctccagc agcgcccgcc acaacgacgg caccgcctgg agcacgctcg
     2521 cgcccgatgt gaggaccagc cgcgtcagcg ccgccgggtc ccgcacctcg tcacgggaag
     2581 ccaacacgac cgacgcaccc gacaccaacg gcaggaacaa ctccaacgcc gcgatgtcga
     2641 acgacaccgt ggtcaccgcc accagccggt cccccgccgc caacggcacc cgctcaccca
     2701 caccactcaa atgcgccgac aacgcaccgt gcgacaccac cacacccttc ggacgccccg
     2761 tcgaccccga cgtgtagatc acgtaggcgg cgtcctggga gcgcaccacc gcttccagcg
     2821 gtcggtcgtc cagcgccgcc acggcggggt ccgacaccag cacgggtgcg acgcctgcgg
     2881 gcagtaccgg cgcgcgctgc gccgaggtca ccacgcccac cggcgcggcg tcctccagca
     2941 cgtacgcgag ccgctccgcc gggtactccg ggtccagcgg gaggtatgca ccgccggtct
     3001 tcgtcaccgc cagcagtgcc acgaccagtt cggccccgcg ttccaggcac acgcccacca
     3061 cggagcccgg gcccacgccg gagtcggcga ggtgacgcgc cagccggttc gcccgcgcgt
     3121 ccagctccgc gtacgacacc tccacgccgt cggagacgac cgcgaccgcc tccggtgcgc
     3181 gggccacctg cgccgcgaac agttccggca gcggcgccga gggtgcggcc ggcgtcgcgc
     3241 cgccccactc cacgagcagt cgatcccgct cggcggcgtc gagcacctcg accgcggcga
     3301 ccggtgccga cgggtcggcg acgagctggt ccagcacccg caccaggcgc tcggcgagca
     3361 gcccggccga gtcggcgtcg aacaggtcgg cggccaccgt cagcgatccg tgcacaccgg
     3421 cgggcaggcc cgtcgtgtcg aaggtctccc agcagtcgac ctcgaggtcg aacttcgcgc
     3481 cgtggacgtc ggtcgtggcc acttccaccc gcagcccggg caggtcgagg acggcggcgg
     3541 cgttgttctg caggttgaac atgacctgga acagcgggtg gcgcgccatg gagcggccgg
     3601 gggcgaggtc ctccaccagc ttctcgaacg gcacgtcctg gtgctcgaag gccgacaggg
     3661 cccgctcctg cccccgggcc agcaggtccc ggaagctggg gtcgcccgac aggtcgtggc
     3721 ggatggccag ggtgttgacg aagaagccga ccaggtcgtc cagcgccgag tcggcgcgcc
     3781 cggccaccgc cgagccgatc gggatgtccg taccggcccc gagccgggag agcagcaccg
     3841 ccagggcgct gcgcagcacc atgaacgggg tcagtccctc ggccagcgcc agccgggcca
     3901 gtcgtgcgtg cagctcggcg ggcacctcga gggggacccg gtgtccgcgg taggagccga
     3961 cggtggggcg cggacggtcg aacggcaacg gcagttcgtc cgggacgccg gccagggcac
     4021 cgcgccagaa cccgacctgg cgggccatcc ggctctccgg gtcgttctcg tcgccgagca
     4081 gctcgcgctg ccacagcgcg tagtccgcgt actgcacggg cagcggatcc cattcgggtg
     4141 cccggcccgt ggtgcgggcg gcgtaggccg tcgacaggtc ccgggccagt acccgcatgg
     4201 accagccgtc accggcgatg tggtgggtgg tcaggaccag ggtgtgggcg tcggggccgg
     4261 tcgtgtacag ccaggcccgg atcgggacct cctgtgacag gtcgaaggcg tacgcggccg
     4321 cggcggcgac cgcggcgtcc aggtgcgccg gggccacctc ggccgtggtc agctcccact
     4381 ccagctcgtc gagcttgacg atgctctggt ggggctcgcc gtcggtgacc gcgtacaggg
     4441 tgcgcagcac ctcgtggcgg ccgatcacgt cccggagtgc cgtgtcgagg gcctttcggt
     4501 cgggccggcc cgagaggcga agcacgaccg gaaggttgta cctggcgttc gggccgtcca
     4561 actgcccgat gaaccagagt cggcgctggg cgaaggacag gggaaccatc aggactcctc
     4621 gtggttgcgc atcggccgaa gggccggcct ggttgacttc tcggttccga cccgccgggc
     4681 cagacctgcg acggtccggg cctcgaacac ggcccgcagc ggtatttcga ctcccaggac
     4741 ttcccgtacc cgggtcacca ggcgggtggc gagcagggag tgccctccca gggcgaagaa
     4801 gtcgtcgtcc atcccgacct tgtcgaggcc gaggacctcg cggaacagat cgctgacggc
     4861 cgcctcgcgg ctgtcggccg gtccgcggcc ctcgcccacc cggtactcag gtgccggcag
     4921 ggccttgcgg tcgagcttcc cgttggcggt cagcggcagg gcgtcgagca ccacggtcgc
     4981 cgcggggacc aggtactccg gcagtcgatc ggccaggaac ccctggatga cggaagggag
     5041 ttcattcggt gcgtcgtggt cggcgacggc gtaggccacc agccggacct gtccgggagt
     5101 gtcctcccgg gcgatgacgg cggcctgcac caccagcggg tgcgaggcca ccacgctctc
     5161 gacctcgccc ggctccacgc ggaagccgcg gatcttgacc tggtggtccg tgcggcccgc
     5221 gaagaggagc cgtccctgcg cggtccagct cgcccggtcc cccgtgcggt acatccgtgc
     5281 gcccggttcg aacgggcagg ccacgaaccg ctccgcggtc agggcgggct gtccgccgta
     5341 gccgcgggcg aggcccgcgc ccgtggtgta gaggtctccc tccacgccga ccggcaccgg
     5401 ccgcagcccg gcgtccagca cgtacacccg ggtgtcggcg accggcgtgc cgatcggcac
     5461 cgatccggcg tcctcgccca gttccgccgc gagcacctcg tggactgcgg tgaaggtggt
     5521 gttctcggtc ggtccgtagc cgttgaacag ccggagcgaa ggcagtgcgg cgagcagtcg
     5581 gcggcagtgg gccaccgaca gcgcgtcacc gcccgccagt agtcgtcgca cgcccgcgag
     5641 cacggacacg tcctggtcga ccacctcgtg gaacaggccc gccgtgagcc agagggtgtc
     5701 cacgccgtgc tcgcgcagga aggtgccgac ctcggcgacc gacagggcgc cgggtgccgg
     5761 aaccgccagg gtcgccccgt tcagcagcgc gccccagatc tcgaaggtgg ccgcgtcgaa
     5821 cgaggcggac gccagctggg ccaccacgtt cccgggaccc ggttccagga acccgttgcg
     5881 gcgcaccagt cggtcgaccg cccggtgcgg tacggccgtg cccttgggca ggccggtcga
     5941 accggatgtg tagacgacgt aggccgtgtg gtcggggccg ggctcggcgc tgcgttctcc
     6001 ggtccccagc ggggcgccgg agaggccggc cgattcctcg tccgcttccc acggcgcgag
     6061 ccggggcagg tccccggctc cgacgccggc cgcgccgtcc gtcagtacga gcgtcgccga
     6121 ggagtcccgc agcatgtggg cgatccggtc cgccgggtac gacaggtcca ccgggaggta
     6181 tgcgccgccc gccttcacca ccgcgagcag cgagaccacc aggtcggcgc cgcgcggcag
     6241 ggccaccgcc acgaccgact ccggtcccac gccgcggccc gtcagcagcc gcgccagccg
     6301 gttggcccgc gcgtccagct ccgcgtaggt caggctcccg ccgcccgcga ccaccgccac
     6361 ggcctcgggc gtccgcgcca cctgggccgc gaacagctcc ggcaccgtgg ccgcggccag
     6421 gtcccggccc gtggtgttcc actcgccgag gatccggcgc cgctcctcct cgcccaggac
     6481 ctcgaccgcg cccagcggca cgtcggggcc gccctccagg gccgcctcca gcgccgtgac
     6541 gaggttggcg gcggcggtac ggacgagctc gcccaccgcg acgccgtcgg ccggggccac
     6601 cgcgtcgatg gacaggtcga tgtccacacc gttgtcgtcg accatcagcg ccagcgggaa
     6661 gttggtgcgt tcccgggcga acaccagacg ggtgccgagg agttcgccgt cccagcgctc
     6721 gtccaggttc tgtccggcgt tgcgccggta gttgaggaag gtggtgaaca gcgggctgcc
     6781 gcccgccacc cggctggcgc gctgggcgac caccagcggg gcgtgctcgt gttccagcag
     6841 ctccgccagt tggctccgca tcgcggagac cgcggccacc acgcccgggc cgtcgtggtt
     6901 cacccgcacc gggagggtgt tgatgaaggg gccggggatc cggtcggcgc cctcgccggc
     6961 gttcatccgg ccggacagga cggtgccgaa cacgacgtcc tgcccgtggg acacggccga
     7021 gagcacccgt gcccacacca cgtgcagcag cgtcgcgggg ctcgtgccca ggcggcgggc
     7081 gacttcgcgc agccggacgt ccacttccgg cgccggggcg acccggctgc ggaccagggc
     7141 ggcgccgtcg ccgcgcacgt cgaccaggcc gaacggggcc gtcggctcct cgatgtcgcc
     7201 cagcaggcgc tcgaagtacc gggcgtgctc ggactgtggc accccgccgc gggcctgtgc
     7261 gacgaagttg cggtacggca acggctcggg caggtcggcc tcgtgtccgg tgacgaaggc
     7321 ctggacctcc gtcagcagga cgaccagggc cgtgtggtcg cgcaccatgt ggtgggcccg
     7381 gatcagggcc agccacttgc cgccgctgcc ggggagggcg gcggtgtgca gggtgatcag
     7441 cggggggctg gacaggtcca tggagtggcc gcccaggtcg accagctcgg ccaccgggtc
     7501 ggggctcgcg gggtccaggg tgacctcggt gacggggagc tccgcgtgcc gcagcaccac
     7561 ctggaccggc tcgcgcaggc cctgccagac gtacgaggtc cggtagatgt cgtgccggtt
     7621 caccacctcg ttcacggccc gggagaacgc gtccagacgt gcgcgggagt cgaattcgag
     7681 caccgccggc atcacgtagg cgtcctcgcc cccgtcggcc agcatgtggt ggaagagcag
     7741 gccttcctgc agcggggcca gcggatagac gtccgccacg ttggccgcgc cgccggggac
     7801 gctcgcgacc accttggcga tctcctgctc cgagaggtcc accatggaga gcatctccgg
     7861 ggtgatctcc gtcgcgccga gggggatccg gttggccggg gcctcgatcc gcacggcgcc
     7921 gacggaggcc gccacaccgg caggggtcgg gttgtcgaac agggtgcgga ccgatacgga
     7981 gacgccctgc acccgcagga tctccaccag ccgcaccgcc accagcgagt ggccgcccag
     8041 ctcgaagaag tcgtcctcga ccccgacccg ctccagcccc agcacctcgg cgaaggccgc
     8101 gcagacgatc tcctcgcggg cgtccgccgg gccccggccg gaaccggcca gacccacgaa
     8161 gtccggcgcc gggagcgcct tgcggtccag cttgccgttg cccgacagcg gcagcgcgtc
     8221 catgacgacc accgcggacg gcaccaggtg ctccggcagc cgctccgcgg tgaactgccg
     8281 gatctgcgcg gcgaatccct cggtctccgc accgtcgccg ggcactgcgt aggcgaccag
     8341 ggaggtgtcg ccgagggcgt cctggcgcgc gacgaccgcg gcctgggcga ccagcgggtg
     8401 cgcggcgacg gccgcctgga cctcaccggg ttcgatgcgg tatccgcgga tcttcacctg
     8461 ctcgtcggcg cgccccagga agaccagccg gccgtcggtg gtccacttcg ccaggtcgcc
     8521 ggtgcggtac atccggccac cggactcgta cgggttggcg acgaaccgct cggccgtctg
     8581 gcccgcccgg cggacgtagc cgcgggccag ctgcgcgccc gcgacgtaga gacctccggc
     8641 cacgcccacc gggaccggtt ccagccggtc gtccaggacg aagacccggg tgttgccgac
     8701 aggccgtccg atcgggacct cgccgtcggc gaccagctcg gcggtgagcc gggtggtggc
     8761 gacgccgatg gtggtctcgg tcgggccgta gtggttgtgg acggcgcggt cgccggctcc
     8821 ggcgaccagc tcgcgcaccc agccgggggc cgccgcctca ccgccgagta cgagggactt
     8881 cgccgggagg acgtccgtgg gaccggccac ggcgctcagc gccgcgaggt gggaggggac
     8941 gaccttgagg tggtcgatgg cgtgctcggc caggtacgcg gagaccgcgg ccggatcggt
     9001 caccgcaccc tcctgaagga tgtgcagctc tccgcccgtc accaggctcg cgaagaggac
     9061 ggtgttcccg aggtcggtca cctgggcctg gagcagcgcg taccggctgc ccgccccggt
     9121 gaacccgatg cgcgggggga ccgtggagac gtagttggtc agcgcgccgt gggtgacggc
     9181 cacgcccttc ggcctgccgg tcgaaccgga ggtgtagatc acgtaggcga ggccggcggg
     9241 gtcggtcacc acctcgggcg cggtggacgg cgccgccgcc agctgcatgg ccgtcagcgt
     9301 cccgtcgagc gccaccgtcc ggatccggcc cgcgggcagg tcgtccagga tctcctctgt
     9361 ggtgagcacc agagtgacac tgctgtcctt catcatgaac gccgtgcgat cggcgggctg
     9421 ttccgggtcg agcgggaggt aacccgcccc cgccttccag acggccagca tcccggtgat
     9481 catctcggcg ccgcggggca gcgcgagacc gaccacggat tcggctccga tgccctgcgc
     9541 gaccaagtgg tgggctatcc ggttggcccg gacgtccagc tcggcgaagg acacccgctc
     9601 gccgtcggcg acgatcgccg cggcgtcggg cgtacgggcg acctgcgccc cgaagagacc
     9661 cgcgaccgag tcggccggca cttcctccgc cgtaccgttc cactccgtca gcagccgggt
     9721 ccgctcgtcg tcctccagca cgcggaccgc gctcaacgct gtctgggggc cgccgtccag
     9781 cgccgcctcc agggccgtca cgaggctcgc gacggcggta cggacctggg cgccgaccgt
     9841 gtgggagtcg atcggggcca ccgcgtccac ggcgacctcg atcccgtcgt cgttgtcgtc
     9901 gaccaggatc acgagcgggt agttggtgcg ctcccgcgag agcagcagcc tggtcccctc
     9961 catcaccgcg cccgcacgct cttcggggct ctgaccctcg ttgcgccggt agttgaggaa
    10021 ggacgtgaac agcggggtgt cacccacgag gccactggcc cgctgcgcgg ccacgagcgg
    10081 cgcgtgctcg tgctcgagca gttcggccag ctggttgcgc atggcggtga cggcgtcgag
    10141 cacgccctgg cggcccgcca ggacacgtac gggaagcgtg ttcatgaagg gtccgggcac
    10201 ccggtcggcg cccgcgccgg cgttcatccg gccgtacagc accgtgccga agaccacgtc
    10261 gtcacggccg ctgaccgcgg ccagcacccg cgcccacgcc acgtgcagca gcgtcgccgg
    10321 gctggtcccg atgcggcgtg cggcctcgcg cagtcgaatg ctcaagtcgg caccgaatga
    10381 ggtgacttcg tgcacggtgt cggctccgtc gccgcgcacg ttcagcagtc cgtacgccgc
    10441 ggtcggctcc gtcacgtccc ccagcagacg ggcgaagtac cgctcgtgct ccacgagcgg
    10501 caccccgccg cgggtctggg cgacgaagtt gcggaagggc atcggggcgg gcagctgcgc
    10561 gctccggccg gtcacgatcg tccgcacctc gctgagcacc acctccagcg cggtgtggtc
    10621 acgcaccgtg tggtgcatgc gggcgagtgc catccagccg ccgcccggca gccgtgcgta
    10681 gtccaccgcg atcagcgggg cccggccgag gtccatcagg gaaccgacga tcgcctgcag
    10741 gtcggcggcc gggtcggtcg tggccgggtc gagggtcacc tcgttcaccg gcaggacggc
    10801 cttgcgccag acgacctgga ccggctcgcg cagtccctcc cagacgaacg aggtccggaa
    10861 gatgtcgtgc cggtccacca ccagctggag cgcctcgacg aaggcctcca gccggtcctt
    10921 cgtgtcgaac tccattgcgg cacgcagcac ataggcgtcc tcgccgccgt cggcgaggag
    10981 gtggtggaag agcaggccct cctggagggg ggccagggga tagacgtccg cgacgttcgc
    11041 ggggccgccc tcgacggtcg cgacgatccg ggcgacctcg tcggcggtca ggtcgaccag
    11101 cggcagcatc tccggcgtga tctccgtcgc gtcgacgggg atcaggttct ccggcaccac
    11161 gacctgggcg gcgccggtcg agtccgcgag ggcggccggg gtcggggaac ggaagaactc
    11221 cctcaccgac gtggacacac cgtgcccgcg cagcacctcc atcaggcgca cggcgagcag
    11281 cgagtggccg ccgagccgga agaagtcgtc gtcgacaccg acgctctcca ggcccagcac
    11341 ctcggcgaag gccgcgcaga cgatctcctc gcgtgcgttc gccggcccgc ggccggaccc
    11401 ggccgtgtac tcgggggcgg gcagggcctt gcggtccagc ttcccgttca ccgacaacgg
    11461 cagcgcgtcc agaacgacga ccgccgacgg aaccatgtac tcgggaagac ggccggcgac
    11521 gaactcccgg acgtcctcct cctgtacgga accctcgccg acggggacga cgtaggcgac
    11581 cagacgcttg tcgcccgaca cgtcctcgcg ggcgaccaca gccgcctgcg ccacctgcgg
    11641 atgggccgcg accacggcct ggacctcacc cggctcgatc cggaaaccac ggaccttcac
    11701 ctgctcgtcc acacgcccca ggtactccac ctgaccgtcc gcgttccacc gcaccacatc
    11761 acccgtgcgg tagagacgct caccagtgcc gtacggagaa gccacgaaac gctccgccgt
    11821 cagaccggga cggttcgcat aaccacgagc cagctgcaca cccgcgagat acaactcacc
    11881 cgccacaccg acgggaaccg gccgcagccc tgcatccagc acgtacaggc gggtgttggc
    11941 gaccggggca ccgatcggta ccgtcccggt gctctgctcc ggacggcact gccaggccgt
    12001 cacatcgacc gacgcctctg tcggaccgta gaggttgtgc agctcgacac cgtcgaacac
    12061 ctcgaagaaa cgccgctgc
//
