LOCUS       NZ_BMVL01000035        13167 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence35, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000035
VERSION     NZ_BMVL01000035.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 13167)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 13167
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000035.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13167
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            complement(<1..2019)
                     /locus_tag="IE257_RS37400"
     CDS             complement(<1..2019)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (1-300). E-value:
                     1.1e-115. Score: 377.7. Matches aSDomain:
                     nrpspksdomains_IE257_RS37400_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="IE257_RS37400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /protein_id="WP_189974539.1"
                     /sec_met_domain="Condensation (E-value: 7.9e-69, bitscore:
                     219.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-46, bitscore:
                     145.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPLSFAQRRLWFIGQLDGPSPAYNIPIVRRLTGELDPAALNAAL
                     RDVMRRHEVLRTVFPIKDGQPYQRIRKLDELEWELSVVQMPPEDLDDAVAGAARHLFDL
                     AAEVPIRAWLFTTAPDEHVLAVVVHHIAGDGWSMGPLARDVSVAYTARRAGRAPEWEPL
                     PVQYADYTLWQRELLGDEDDPESVMTRQLGFWRNALAGAPEELTLPVDHPRPAVPSHRS
                     LAAPIEVPAELHAKLAELARTEGVSLFVVLQSALAVLLSRLGAGTDIPIGTVVAGRTDV
                     ALDDLVGFFVNSLVLRTDLSGTPTFRELLAQGHDTALSAFENQDVPFEKLVEELAPARV
                     MGRHPLIQTMFTMQNTAQAVLDLPGLGAGGAPESASAAAAARFDLDVLLGEVFDASGAP
                     AGVTGTLLGAADLFEAGSVGRIAERLVRVLELVADDPGLSLDAVDVLDGDERRRVVTEW
                     NATGADFGSGLVPGLFGARVVGAPDAVAVVDDGVEVSFAELDVRANRLARFLVGQGVGA
                     ESVVGVCLPRGVDAVVAILAVWKAGAAFLPIDPGYPVDRISFMLADSGAVLTLTDEEIL
                     GDLPAGRARMVALDSTLMGVQLSMLEDTAPEVSVSADGLAYVIYTSGSTGRPKGVAVTH
                     GGLANYAQWAAGSYGAAGGAPLHSSLAFDLTVTSVVVP"
     source          1..13167
                     /culture_collection="JCM:4726"
                     /db_xref="taxon:1895"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces avidinii"
                     /strain="JCM 4726"
                     /submitter_seqid="sequence35"
                     /type_material="type strain of Streptomyces avidinii"
     cand_cluster    1..13167
                     /SMILES="NC(CC(=O)N)C(=O)NC([*])C(=O)NC(Cc1ccccc1)C(=O)NCC(
                     =O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13167
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:13130](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..13130)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       complement(115..174)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37400_0007"
                     /evalue="3.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS37400"
                     /protein_end="635"
                     /protein_start="615"
                     /score="34.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVTH"
     CDS_motif       complement(373..414)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37400_0006"
                     /evalue="9.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS37400"
                     /protein_end="549"
                     /protein_start="535"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LAVWKAGAAFLPID"
     CDS_motif       complement(961..1080)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37400_0005"
                     /evalue="1.10E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE257_RS37400"
                     /protein_end="353"
                     /protein_start="313"
                     /score="66.0"
                     /tool="antismash"
                     /translation="HDTALSAFENQDVPFEKLVEELAPARVMGRHPLIQTMFTM"
     aSDomain        complement(1120..2016)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37400_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.10E-115"
                     /label="IE257_RS37400_Condensation_LCL.1"
                     /locus_tag="IE257_RS37400"
                     /protein_end="300"
                     /protein_start="1"
                     /score="377.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAGDG"
                     /tool="antismash"
                     /translation="IPLSFAQRRLWFIGQLDGPSPAYNIPIVRRLTGELDPAALNAALR
                     DVMRRHEVLRTVFPIKDGQPYQRIRKLDELEWELSVVQMPPEDLDDAVAGAARHLFDLA
                     AEVPIRAWLFTTAPDEHVLAVVVHHIAGDGWSMGPLARDVSVAYTARRAGRAPEWEPLP
                     VQYADYTLWQRELLGDEDDPESVMTRQLGFWRNALAGAPEELTLPVDHPRPAVPSHRSL
                     AAPIEVPAELHAKLAELARTEGVSLFVVLQSALAVLLSRLGAGTDIPIGTVVAGRTDVA
                     LDDLVGFFVNSLVLRTDL"
     CDS_motif       complement(1129..1218)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37400_0004"
                     /evalue="1.00E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE257_RS37400"
                     /protein_end="297"
                     /protein_start="267"
                     /score="43.6"
                     /tool="antismash"
                     /translation="DIPIGTVVAGRTDVALDDLVGFFVNSLVLR"
     CDS_motif       complement(1486..1524)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37400_0003"
                     /evalue="7.00E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="IE257_RS37400"
                     /protein_end="178"
                     /protein_start="165"
                     /score="18.5"
                     /tool="antismash"
                     /translation="QYADYTLWQRELL"
     CDS_motif       complement(1573..1638)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37400_0002"
                     /evalue="2.00E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE257_RS37400"
                     /protein_end="149"
                     /protein_start="127"
                     /score="33.1"
                     /tool="antismash"
                     /translation="VHHIAGDGWSMGPLARDVSVAY"
     CDS_motif       complement(1840..1956)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37400_0001"
                     /evalue="3.30E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE257_RS37400"
                     /protein_end="60"
                     /protein_start="21"
                     /score="61.3"
                     /tool="antismash"
                     /translation="PAYNIPIVRRLTGELDPAALNAALRDVMRRHEVLRTVFP"
     gene            complement(2019..13130)
                     /locus_tag="IE257_RS37405"
     CDS             complement(2019..13130)
                     /NRPS_PKS="Domain: AMP-binding (25-288). E-value: 4.2e-66.
                     Score: 215.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (398-463). E-value: 1.7e-23. Score:
                     74.6. Matches aSDomain: nrpspksdomains_IE257_RS37405_PCP.1"
                     /NRPS_PKS="Domain: Condensation_Dual (512-803). E-value:
                     6.9e-115. Score: 375.3. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_Condensation_Dual.1"
                     /NRPS_PKS="Domain: AMP-binding (971-1355). E-value:
                     1.7e-99. Score: 325.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1461-1523). E-value: 7.1e-23.
                     Score: 72.6. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_PCP.2"
                     /NRPS_PKS="Domain: Condensation_Dual (1576-1867). E-value:
                     1.9e-106. Score: 347.7. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_Condensation_Dual.2"
                     /NRPS_PKS="Domain: AMP-binding (2038-2428). E-value:
                     9.7e-104. Score: 339.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (2534-2598). E-value: 1.8e-23.
                     Score: 74.5. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_PCP.3"
                     /NRPS_PKS="Domain: Condensation_Dual (2648-2939). E-value:
                     3.7e-112. Score: 366.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_Condensation_Dual.3"
                     /NRPS_PKS="Domain: AMP-binding (3111-3508). E-value:
                     3.7e-107. Score: 350.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_AMP-binding.4"
                     /NRPS_PKS="Domain: PCP (3618-3685). E-value: 1.2e-25.
                     Score: 81.5. Matches aSDomain:
                     nrpspksdomains_IE257_RS37405_PCP.4"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /locus_tag="IE257_RS37405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_189974541.1"
                     /sec_met_domain="Condensation (E-value: 2e-51, bitscore:
                     161.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.9e-116, bitscore:
                     374.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5e-16, bitscore:
                     46.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVALDSTLMGVQLSMLEDSAPEVVTRSEGLAYVIYTSGSTGRPKG
                     VAVTHGGLANYAQWAARSYGAAEGGAPLHSSLAFDLTVTSVVVPLISGAPVVVSREGGA
                     EGLAELLRDGGGFGLTKAVPAHLPLLSEMLTDGEVKGAVSTWVVGGEALSGSVVQAWLE
                     RAPGSVVVNEYGPTETVVGCAVFEVRAGDEIGDVVPIGRPVANTQLYVLDGFLRPVAPG
                     VAGELYIAGAQLARGYVRRPELTAERFVASPFERGGRMYRSGDLARWRVDGQLEFLGRA
                     DEQVKVRGFRIEPGEVQAVVAGHPQVAQVAVVAREDVPGDVRLVAYVVADDPDDDLAAL
                     PGLVRAFVSGRLPEYMVPSAVVVLEALPLTGNGKLDRKALPAPELAGAGTGRAPANERE
                     EILCAAFAEVLGLESAGVDDDFFALGGHSLLAVHLVEVLRKHGVSVSVRALFDTPTPAG
                     LALSVGTIESVVPANLIPADAVEITPELLPLVDLTVDEVERIVSTVDGGAANVADIYPL
                     APLQEGLLFHHLMAEGGEDAYLMPVVVEMDSRERVEEFARAFQLVVDRHDILRTSFVWE
                     GLREPVQVVWRKAVLPVIEVDLDPAAADPAAALQAAVGLSMDLSRAPLVSVHAAALPDG
                     KRWLVLLRLHHLVQDHTALELLLHEVQVFLAGRDDELPRPLPFRDFVAQVRGGVDRAEH
                     ERYFAELLGDVTEPTAPYGLVDVRGDGTDVERAVVPLAPESLERLRAVARRVGTSPATV
                     LHVAWARVLAAVSGHSDVVFGTVLFGRMNAGAGADRVAGLYLNTLPVRVRTGELGALEA
                     VTAMRGQLAGLLEHEHASLALAQQASGLAGKTPVFTSLINYRHNTGAEAEKEGYARPEG
                     MRMLSSRERTNYPLGVSVDDNGDSMSFAVDAVAPIDAEAVGLLLREAVETLVPLVEQAL
                     DGGADTALRTVHVLTPEDRHRMLVRWNDTGSEVASASVPELFAAQVARTPEAVAVVADG
                     AEVSYAELDARANRLARYLVGRGVTAGSVVGVCLDRGVDLLVAVLAVVKTGAAYMTIDP
                     EYPAQRVAYMLEDASPVVVLASAGTRRLAPDALLVDDLAVADLDGGLLDVVVRAQDAAY
                     VIYTSGSTGRPKGVVVSHAGVASLVAGQSRYLGVGAGARVGQYGSVGFDAFAWEWFMAL
                     LTGAALVVIPHEQRLGEALPAFLAERAVTHVALPQAVLATLDEDSIGGDVVLVTGGEAL
                     PPEVMARWARGHRLFNSFGPAETTVDATLWRCDPEAGEVAIGVPVVNTRVFVLDEFLAP
                     VPVGVAGELYVAGAGLARGYLGRPALTAERFVANPFHGAGERLYRTGDRARWTADGQLV
                     FAGRTDDQVKIRGFRIEPGEIENVLDSHPRVTQAAVIVREDAPGDRRLVAYVVADGARG
                     DLPEALTRLAAERLPAYMAPSAVVLLDELPLTVNGKLDRGALPAPVYATGGGRAPANAR
                     EEIVCAAFAEVLGVASVGVDEDFFQLGGHSLLAVRLVEVLRANGVPVSVRALFQTPTPA
                     GLALPTGSARALEVPANLIPADAVEITPEMLPLVDLTTEEVARIVATVPGGAANVADVY
                     PLAPLQEGLVFHHVLADGGEDAYVTPVVFEVESAELLEEFTGALQQVIDRHDIFRTSLV
                     WEGVREPVQVVRRRAPLSVEQVTLEAHGAEPVDQLLAAGGMSMDLGRAPLLTMHVAAVP
                     GSSRRLMLLKVHHAVQDHTAMEVVLGEVQAFLTGRGDSLPQPVPFRNFVAQARGGAERS
                     EHERYFTQLLGDVEEPTAPFGLVDVLGDGADVTRVHVPFAPELHARLRAVSARLSTSAA
                     TVLHVAWARTLAAVSGRGDVVFGTVLFGRMNSGAGSADMPGPFINTLPVRVRTGALGVL
                     EAVDAMRGQLAELLEHEHASLAQAQRASGLQGDAPLFTALFNYRHNAPGSATGANDDRT
                     RGFEGFTAVHSRERTNYPLAVSVDDDGESIALAVDAVSVIDGEAVGELMRSVAENLVTA
                     LETALDGGTEQRLGALGVLDEDTSRRMLVEWNDTALDIEPRTAADLFAAQVYRAPQAVA
                     VVADGVEVSYAELDARANRLARLLASRGVGPESLVAVCLDRGVELLVAVLGVLKAGGAY
                     MTVDPEYPAERVAYMLRDAEPRVLLASAATEAVLPGAVLLDDPEVVAALGRLDGGAPRL
                     AGQSVAHPAYVIYTSGSTGRPKGVLVPHAGVASMTAGHTALLGVGPGHRVGQFASIGFD
                     AFAWEWFMALLTGATLVVIPPDRRVGNDLAQFLTEQAVTHVTLPPAVLVTLDENTVSKD
                     LALVTAGEALPPETAARWAAGRRMFNAYGPAETTVDATCWSVDPETADEVAIGAPVVNT
                     RVFVLDEFLAPVPVGVAGELYVAGAGLARGYLGRPALTAERFVANPFHGAGERLYRTGD
                     RARWTADGQLVFAGRTDDQVKIRGFRIEPGEVENVVAAHPRVTQAAVVVREDTPGEKRL
                     VAYVVGDGAPGELPEPILRSAAERLPAYMVPSAVVVLDALPMTVNGKLDRKALPAPAYA
                     AGGGRAPANAREEIVCAAFAEVLGLESVGVDDDFFRLGGHSLLVVRLVEVLRDNGVSVS
                     VRTLFQSPTPAGLAASTGAVQVDVPANLIPAGATEITPDMLPLVTLSEQEVATVVATVP
                     GGAANIADVYPLAPLQEGLLFHHMLADGGEDAYVSKEVFELVSRERLEEFARALQQVLD
                     RHDIFRTSLVWEGLREPVQVVWRRAPLSVEEVSLDADGADPVEQLLAIGGTSMDLGRAP
                     LFTLHIAAVPGSDHWLMLLKVHHAVQDHVALEVLHSEVQAFMTGEDEGLPEPVPLRNFV
                     AQARGGVAEQEHERYFTELLGDVDEPTAPFGLVDVHGDGGDTVWVRKPLGPELHTRLRE
                     VSHRLGTSAATVLHVAWARTLAAVSARTDVVFGTVLFGRMNSGAGADRVPGPFINTLPV
                     RVRTAELGALAAVGAMRLQLAELLEHEHASLALAQRASGLAGDTPLFTAIFNYRHNAGG
                     SGQAADAERNRGFEGLELRYARERTNYPLVVAVDDNADSLELTVDAVHSIDVHAVVRLM
                     CTATENLVAALEGELDGGPEQPLAAVRVLGEDDLHRILDEWNDTGRDGVATVPVTELFA
                     AQVARAPDATAVVSEGVEVSYAELDARAERLARYLNRRGVGPESVVGVALDRGVELVVA
                     LLAVMKAGGAYLPMDPEYPADRVAYMIGDAGVALVLTAQGPTGWLEDLGVAIVALDDPE
                     TVAELARPDEHEPSAGIRRTSLPEHPAYLIYTSGSTGRPKGVVVSHGALSAHLCGVGER
                     VPLVAGDRLVAVTTVSFDIAALELFLPLVSGASVVVASREVVRDPAALTGLVVSSGASV
                     VQGVPSLWRGLLEEVGWPAGVRALVGGEALPPELAQRFTDLGVGAVNLYGPTEVTVWAT
                     SEEVAAGPVLVGRPFADVAAYVLDGWMRPVPAGVAGELYLSGAQLARGYAGRPGLTAER
                     FVASPFGGAGERLYRTGDLARWMGDGRLECLGRADEQVKVRGFRIEPGEIEAVLAARDW
                     VARAVVIVREDKPGDQRLVAYVVPVEGAEEPPEGFAQSLRAAVQDQLPSYMVPSAVVPL
                     HALPLTANGKLNRKALPAPEYTSGEGRAPANRQEELLCQAFAEVLGLERVGVDDDFFAL
                     GGHSLLATRLISHIRALLRVDFSLRALYKTPTVAGVARQLGTQKTARPALRPMRTNEEY
                     "
     aSDomain        complement(2076..2276)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_PCP.4"
                     /evalue="1.20E-25"
                     /label="IE257_RS37405_PCP.4"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3685"
                     /protein_start="3618"
                     /score="81.5"
                     /tool="antismash"
                     /translation="EELLCQAFAEVLGLERVGVDDDFFALGGHSLLATRLISHIRALLR
                     VDFSLRALYKTPTVAGVARQLG"
     aSModule        complement(2076..5186)
                     /complete
                     /domains="nrpspksdomains_IE257_RS37405_Condensation_Dual.3"
                     /domains="nrpspksdomains_IE257_RS37405_AMP-binding.4"
                     /domains="nrpspksdomains_IE257_RS37405_PCP.4"
                     /locus_tags="IE257_RS37405"
                     /monomer_pairings="Gly -> Gly"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2325..2351)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0042"
                     /evalue="2.40E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3602"
                     /protein_start="3593"
                     /score="2.0"
                     /tool="antismash"
                     /translation="GKLNRKALP"
     CDS_motif       complement(2538..2561)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0041"
                     /evalue="1.60E+01"
                     /label="C4_dual_169-182"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3531"
                     /protein_start="3523"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="RDWVARAV"
     CDS_motif       complement(2577..2642)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0040"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3518"
                     /protein_start="3496"
                     /score="36.4"
                     /tool="antismash"
                     /translation="CLGRADEQVKVRGFRIEPGEIE"
     aSDomain        complement(2607..3797)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_AMP-binding.4"
                     /evalue="3.70E-107"
                     /label="IE257_RS37405_AMP-binding.4"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3508"
                     /protein_start="3111"
                     /score="350.4"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="FAAQVARAPDATAVVSEGVEVSYAELDARAERLARYLNRRGVGPE
                     SVVGVALDRGVELVVALLAVMKAGGAYLPMDPEYPADRVAYMIGDAGVALVLTAQGPTG
                     WLEDLGVAIVALDDPETVAELARPDEHEPSAGIRRTSLPEHPAYLIYTSGSTGRPKGVV
                     VSHGALSAHLCGVGERVPLVAGDRLVAVTTVSFDIAALELFLPLVSGASVVVASREVVR
                     DPAALTGLVVSSGASVVQGVPSLWRGLLEEVGWPAGVRALVGGEALPPELAQRFTDLGV
                     GAVNLYGPTEVTVWATSEEVAAGPVLVGRPFADVAAYVLDGWMRPVPAGVAGELYLSGA
                     QLARGYAGRPGLTAERFVASPFGGAGERLYRTGDLARWMGDGRLECLGRADEQVKVR"
     CDS_motif       complement(2727..2816)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0039"
                     /evalue="6.00E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3468"
                     /protein_start="3438"
                     /score="47.3"
                     /tool="antismash"
                     /translation="PAGVAGELYLSGAQLARGYAGRPGLTAERF"
     CDS_motif       complement(2916..2939)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0038"
                     /evalue="6.50E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3405"
                     /protein_start="3397"
                     /score="3.6"
                     /tool="antismash"
                     /translation="YGPTEVTV"
     CDS_motif       complement(3300..3359)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0037"
                     /evalue="2.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3277"
                     /protein_start="3257"
                     /score="32.0"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGRPKGVVVSH"
     CDS_motif       complement(3570..3611)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0036"
                     /evalue="8.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS37405"
                     /protein_end="3187"
                     /protein_start="3173"
                     /score="15.9"
                     /tool="antismash"
                     /translation="LAVMKAGGAYLPMD"
     CDS_motif       complement(4200..4265)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0035"
                     /evalue="9.90E-07"
                     /label="C67_dual_14fromHMM"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2977"
                     /protein_start="2955"
                     /score="21.4"
                     /tool="antismash"
                     /translation="LAELLEHEHASLALAQRASGLA"
     aSDomain        complement(4314..5186)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_Condensation_Dual.
                     3"
                     /domain_subtypes="Condensation_Dual"
                     /evalue="3.70E-112"
                     /label="IE257_RS37405_Condensation_Dual.3"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2939"
                     /protein_start="2648"
                     /score="366.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHAVQDH"
                     /tool="antismash"
                     /translation="DVYPLAPLQEGLLFHHMLADGGEDAYVSKEVFELVSRERLEEFAR
                     ALQQVLDRHDIFRTSLVWEGLREPVQVVWRRAPLSVEEVSLDADGADPVEQLLAIGGTS
                     MDLGRAPLFTLHIAAVPGSDHWLMLLKVHHAVQDHVALEVLHSEVQAFMTGEDEGLPEP
                     VPLRNFVAQARGGVAEQEHERYFTELLGDVDEPTAPFGLVDVHGDGGDTVWVRKPLGPE
                     LHTRLREVSHRLGTSAATVLHVAWARTLAAVSARTDVVFGTVLFGRMNSGAGADRVPGP
                     FINTLPVRVR"
     CDS_motif       complement(4320..4415)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0034"
                     /evalue="3.70E-13"
                     /label="C5_dual_260-291"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2937"
                     /protein_start="2905"
                     /score="41.8"
                     /tool="antismash"
                     /translation="DVVFGTVLFGRMNSGAGADRVPGPFINTLPVR"
     CDS_motif       complement(4656..4694)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0033"
                     /evalue="9.50E-03"
                     /label="C4_dual_169-182"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2825"
                     /protein_start="2812"
                     /score="9.1"
                     /tool="antismash"
                     /translation="PLRNFVAQARGGV"
     CDS_motif       complement(4731..4790)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0032"
                     /evalue="2.90E-04"
                     /label="C3_dual_135-156"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2800"
                     /protein_start="2780"
                     /score="13.9"
                     /tool="antismash"
                     /translation="HHAVQDHVALEVLHSEVQAF"
     CDS_motif       complement(4998..5111)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0031"
                     /evalue="1.80E-16"
                     /label="C2_dual_024-063"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2711"
                     /protein_start="2673"
                     /score="52.6"
                     /tool="antismash"
                     /translation="YVSKEVFELVSRERLEEFARALQQVLDRHDIFRTSLVW"
     CDS_motif       complement(5139..5180)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0030"
                     /evalue="2.40E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2664"
                     /protein_start="2650"
                     /score="19.9"
                     /tool="antismash"
                     /translation="YPLAPLQEGLLFHH"
     aSDomain        complement(5337..5528)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_PCP.3"
                     /evalue="1.80E-23"
                     /label="IE257_RS37405_PCP.3"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2598"
                     /protein_start="2534"
                     /score="74.5"
                     /tool="antismash"
                     /translation="EEIVCAAFAEVLGLESVGVDDDFFRLGGHSLLVVRLVEVLRDNGV
                     SVSVRTLFQSPTPAGLAAS"
     aSModule        complement(5337..8402)
                     /complete
                     /domains="nrpspksdomains_IE257_RS37405_Condensation_Dual.2"
                     /domains="nrpspksdomains_IE257_RS37405_AMP-binding.3"
                     /domains="nrpspksdomains_IE257_RS37405_PCP.3"
                     /locus_tags="IE257_RS37405"
                     /monomer_pairings="Phe -> Phe"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(5577..5603)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0029"
                     /evalue="3.40E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2518"
                     /protein_start="2509"
                     /score="4.3"
                     /tool="antismash"
                     /translation="GKLDRKALP"
     CDS_motif       complement(5817..5882)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0028"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2438"
                     /protein_start="2416"
                     /score="36.1"
                     /tool="antismash"
                     /translation="FAGRTDDQVKIRGFRIEPGEVE"
     aSDomain        complement(5847..7016)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_AMP-binding.3"
                     /evalue="9.70E-104"
                     /label="IE257_RS37405_AMP-binding.3"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2428"
                     /protein_start="2038"
                     /score="339.1"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="FAAQVYRAPQAVAVVADGVEVSYAELDARANRLARLLASRGVGPE
                     SLVAVCLDRGVELLVAVLGVLKAGGAYMTVDPEYPAERVAYMLRDAEPRVLLASAATEA
                     VLPGAVLLDDPEVVAALGRLDGGAPRLAGQSVAHPAYVIYTSGSTGRPKGVLVPHAGVA
                     SMTAGHTALLGVGPGHRVGQFASIGFDAFAWEWFMALLTGATLVVIPPDRRVGNDLAQF
                     LTEQAVTHVTLPPAVLVTLDENTVSKDLALVTAGEALPPETAARWAAGRRMFNAYGPAE
                     TTVDATCWSVDPETADEVAIGAPVVNTRVFVLDEFLAPVPVGVAGELYVAGAGLARGYL
                     GRPALTAERFVANPFHGAGERLYRTGDRARWTADGQLVFAGRTDDQVKIR"
     CDS_motif       complement(5967..6056)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0027"
                     /evalue="2.60E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2388"
                     /protein_start="2358"
                     /score="54.9"
                     /tool="antismash"
                     /translation="PVGVAGELYVAGAGLARGYLGRPALTAERF"
     CDS_motif       complement(6165..6188)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0026"
                     /evalue="3.80E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2322"
                     /protein_start="2314"
                     /score="4.3"
                     /tool="antismash"
                     /translation="YGPAETTV"
     CDS_motif       complement(6540..6599)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0025"
                     /evalue="4.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2197"
                     /protein_start="2177"
                     /score="31.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVLVPH"
     CDS_motif       complement(6789..6830)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0024"
                     /evalue="9.60E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS37405"
                     /protein_end="2114"
                     /protein_start="2100"
                     /score="9.7"
                     /tool="antismash"
                     /translation="LGVLKAGGAYMTVD"
     CDS_motif       complement(7395..7484)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0023"
                     /evalue="1.60E-06"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1912"
                     /protein_start="1882"
                     /score="20.4"
                     /tool="antismash"
                     /translation="QLAELLEHEHASLAQAQRASGLQGDAPLFT"
     aSDomain        complement(7530..8402)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_Condensation_Dual.
                     2"
                     /domain_subtypes="Condensation_Dual"
                     /evalue="1.90E-106"
                     /label="IE257_RS37405_Condensation_Dual.2"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1867"
                     /protein_start="1576"
                     /score="347.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHAVQDH"
                     /tool="antismash"
                     /translation="DVYPLAPLQEGLVFHHVLADGGEDAYVTPVVFEVESAELLEEFTG
                     ALQQVIDRHDIFRTSLVWEGVREPVQVVRRRAPLSVEQVTLEAHGAEPVDQLLAAGGMS
                     MDLGRAPLLTMHVAAVPGSSRRLMLLKVHHAVQDHTAMEVVLGEVQAFLTGRGDSLPQP
                     VPFRNFVAQARGGAERSEHERYFTQLLGDVEEPTAPFGLVDVLGDGADVTRVHVPFAPE
                     LHARLRAVSARLSTSAATVLHVAWARTLAAVSGRGDVVFGTVLFGRMNSGAGSADMPGP
                     FINTLPVRVR"
     CDS_motif       complement(7536..7631)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0022"
                     /evalue="5.10E-11"
                     /label="C5_dual_260-291"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1865"
                     /protein_start="1833"
                     /score="35.1"
                     /tool="antismash"
                     /translation="DVVFGTVLFGRMNSGAGSADMPGPFINTLPVR"
     CDS_motif       complement(7875..7910)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0021"
                     /evalue="5.90E-04"
                     /label="C4_dual_169-182"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1752"
                     /protein_start="1740"
                     /score="12.8"
                     /tool="antismash"
                     /translation="PFRNFVAQARGG"
     CDS_motif       complement(7944..8006)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0020"
                     /evalue="5.20E-06"
                     /label="C3_dual_135-156"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1729"
                     /protein_start="1708"
                     /score="19.4"
                     /tool="antismash"
                     /translation="HHAVQDHTAMEVVLGEVQAFL"
     CDS_motif       complement(8214..8327)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0019"
                     /evalue="1.10E-14"
                     /label="C2_dual_024-063"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1639"
                     /protein_start="1601"
                     /score="46.9"
                     /tool="antismash"
                     /translation="YVTPVVFEVESAELLEEFTGALQQVIDRHDIFRTSLVW"
     CDS_motif       complement(8355..8396)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0018"
                     /evalue="1.10E-05"
                     /label="C1_dual_004-017"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1592"
                     /protein_start="1578"
                     /score="18.0"
                     /tool="antismash"
                     /translation="YPLAPLQEGLVFHH"
     aSDomain        complement(8562..8747)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_PCP.2"
                     /evalue="7.10E-23"
                     /label="IE257_RS37405_PCP.2"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1523"
                     /protein_start="1461"
                     /score="72.6"
                     /tool="antismash"
                     /translation="EEIVCAAFAEVLGVASVGVDEDFFQLGGHSLLAVRLVEVLRANGV
                     PVSVRALFQTPTPAGLA"
     aSModule        complement(8562..11594)
                     /complete
                     /domains="nrpspksdomains_IE257_RS37405_Condensation_Dual.1"
                     /domains="nrpspksdomains_IE257_RS37405_AMP-binding.2"
                     /domains="nrpspksdomains_IE257_RS37405_PCP.2"
                     /locus_tags="IE257_RS37405"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(8796..8822)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0017"
                     /evalue="3.50E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1445"
                     /protein_start="1436"
                     /score="1.6"
                     /tool="antismash"
                     /translation="GKLDRGALP"
     CDS_motif       complement(9036..9101)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0016"
                     /evalue="7.10E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1365"
                     /protein_start="1343"
                     /score="37.2"
                     /tool="antismash"
                     /translation="FAGRTDDQVKIRGFRIEPGEIE"
     aSDomain        complement(9066..10217)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_AMP-binding.2"
                     /evalue="1.70E-99"
                     /label="IE257_RS37405_AMP-binding.2"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1355"
                     /protein_start="971"
                     /score="325.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FAAQVARTPEAVAVVADGAEVSYAELDARANRLARYLVGRGVTAG
                     SVVGVCLDRGVDLLVAVLAVVKTGAAYMTIDPEYPAQRVAYMLEDASPVVVLASAGTRR
                     LAPDALLVDDLAVADLDGGLLDVVVRAQDAAYVIYTSGSTGRPKGVVVSHAGVASLVAG
                     QSRYLGVGAGARVGQYGSVGFDAFAWEWFMALLTGAALVVIPHEQRLGEALPAFLAERA
                     VTHVALPQAVLATLDEDSIGGDVVLVTGGEALPPEVMARWARGHRLFNSFGPAETTVDA
                     TLWRCDPEAGEVAIGVPVVNTRVFVLDEFLAPVPVGVAGELYVAGAGLARGYLGRPALT
                     AERFVANPFHGAGERLYRTGDRARWTADGQLVFAGRTDDQVKIR"
     CDS_motif       complement(9186..9275)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0015"
                     /evalue="2.60E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1315"
                     /protein_start="1285"
                     /score="54.9"
                     /tool="antismash"
                     /translation="PVGVAGELYVAGAGLARGYLGRPALTAERF"
     CDS_motif       complement(9381..9404)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0014"
                     /evalue="3.80E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1250"
                     /protein_start="1242"
                     /score="1.5"
                     /tool="antismash"
                     /translation="FGPAETTV"
     CDS_motif       complement(9756..9815)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0013"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1125"
                     /protein_start="1105"
                     /score="33.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVVVSH"
     CDS_motif       complement(9990..10031)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0012"
                     /evalue="5.70E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS37405"
                     /protein_end="1047"
                     /protein_start="1033"
                     /score="7.4"
                     /tool="antismash"
                     /translation="LAVVKTGAAYMTID"
     CDS_motif       complement(10608..10673)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0011"
                     /evalue="8.60E-06"
                     /label="C67_dual_14fromHMM"
                     /locus_tag="IE257_RS37405"
                     /protein_end="841"
                     /protein_start="819"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LAGLLEHEHASLALAQQASGLA"
     aSDomain        complement(10722..11594)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_Condensation_Dual.
                     1"
                     /domain_subtypes="Condensation_Dual"
                     /evalue="6.90E-115"
                     /label="IE257_RS37405_Condensation_Dual.1"
                     /locus_tag="IE257_RS37405"
                     /protein_end="803"
                     /protein_start="512"
                     /score="375.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLVQDH"
                     /tool="antismash"
                     /translation="DIYPLAPLQEGLLFHHLMAEGGEDAYLMPVVVEMDSRERVEEFAR
                     AFQLVVDRHDILRTSFVWEGLREPVQVVWRKAVLPVIEVDLDPAAADPAAALQAAVGLS
                     MDLSRAPLVSVHAAALPDGKRWLVLLRLHHLVQDHTALELLLHEVQVFLAGRDDELPRP
                     LPFRDFVAQVRGGVDRAEHERYFAELLGDVTEPTAPYGLVDVRGDGTDVERAVVPLAPE
                     SLERLRAVARRVGTSPATVLHVAWARVLAAVSGHSDVVFGTVLFGRMNAGAGADRVAGL
                     YLNTLPVRVR"
     CDS_motif       complement(10728..10823)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0010"
                     /evalue="2.00E-13"
                     /label="C5_dual_260-291"
                     /locus_tag="IE257_RS37405"
                     /protein_end="801"
                     /protein_start="769"
                     /score="42.6"
                     /tool="antismash"
                     /translation="DVVFGTVLFGRMNAGAGADRVAGLYLNTLPVR"
     CDS_motif       complement(11061..11102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0009"
                     /evalue="7.00E-04"
                     /label="C4_dual_169-182"
                     /locus_tag="IE257_RS37405"
                     /protein_end="690"
                     /protein_start="676"
                     /score="12.5"
                     /tool="antismash"
                     /translation="PFRDFVAQVRGGVD"
     CDS_motif       complement(11136..11198)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0008"
                     /evalue="8.30E-06"
                     /label="C3_dual_135-156"
                     /locus_tag="IE257_RS37405"
                     /protein_end="665"
                     /protein_start="644"
                     /score="18.7"
                     /tool="antismash"
                     /translation="HHLVQDHTALELLLHEVQVFL"
     CDS_motif       complement(11406..11519)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0007"
                     /evalue="3.90E-17"
                     /label="C2_dual_024-063"
                     /locus_tag="IE257_RS37405"
                     /protein_end="575"
                     /protein_start="537"
                     /score="54.8"
                     /tool="antismash"
                     /translation="YLMPVVVEMDSRERVEEFARAFQLVVDRHDILRTSFVW"
     CDS_motif       complement(11547..11588)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0006"
                     /evalue="2.40E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="IE257_RS37405"
                     /protein_end="528"
                     /protein_start="514"
                     /score="19.9"
                     /tool="antismash"
                     /translation="YPLAPLQEGLLFHH"
     aSDomain        complement(11742..11936)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_PCP.1"
                     /evalue="1.70E-23"
                     /label="IE257_RS37405_PCP.1"
                     /locus_tag="IE257_RS37405"
                     /protein_end="463"
                     /protein_start="398"
                     /score="74.6"
                     /tool="antismash"
                     /translation="EEILCAAFAEVLGLESAGVDDDFFALGGHSLLAVHLVEVLRKHGV
                     SVSVRALFDTPTPAGLALSV"
     aSModule        complement(11742..13055)
                     /complete
                     /domains="nrpspksdomains_IE257_RS37405_AMP-binding.1"
                     /domains="nrpspksdomains_IE257_RS37405_PCP.1"
                     /locus_tags="IE257_RS37405"
                     /monomer_pairings="Asn -> Asn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(11988..12014)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0005"
                     /evalue="3.40E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="IE257_RS37405"
                     /protein_end="381"
                     /protein_start="372"
                     /score="4.3"
                     /tool="antismash"
                     /translation="GKLDRKALP"
     CDS_motif       complement(12240..12302)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0004"
                     /evalue="6.90E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS37405"
                     /protein_end="297"
                     /protein_start="276"
                     /score="34.2"
                     /tool="antismash"
                     /translation="FLGRADEQVKVRGFRIEPGEV"
     aSDomain        complement(12267..13055)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS37405_AMP-binding.1"
                     /evalue="4.20E-66"
                     /label="IE257_RS37405_AMP-binding.1"
                     /locus_tag="IE257_RS37405"
                     /protein_end="288"
                     /protein_start="25"
                     /score="215.1"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="RSEGLAYVIYTSGSTGRPKGVAVTHGGLANYAQWAARSYGAAEGG
                     APLHSSLAFDLTVTSVVVPLISGAPVVVSREGGAEGLAELLRDGGGFGLTKAVPAHLPL
                     LSEMLTDGEVKGAVSTWVVGGEALSGSVVQAWLERAPGSVVVNEYGPTETVVGCAVFEV
                     RAGDEIGDVVPIGRPVANTQLYVLDGFLRPVAPGVAGELYIAGAQLARGYVRRPELTAE
                     RFVASPFERGGRMYRSGDLARWRVDGQLEFLGRADEQVKVR"
     CDS_motif       complement(12384..12470)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0003"
                     /evalue="2.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS37405"
                     /protein_end="249"
                     /protein_start="220"
                     /score="51.7"
                     /tool="antismash"
                     /translation="PGVAGELYIAGAQLARGYVRRPELTAERF"
     CDS_motif       complement(12588..12614)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0002"
                     /evalue="7.30E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="IE257_RS37405"
                     /protein_end="181"
                     /protein_start="172"
                     /score="3.5"
                     /tool="antismash"
                     /translation="EYGPTETVV"
     CDS_motif       complement(12981..13040)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS37405_0001"
                     /evalue="2.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS37405"
                     /protein_end="50"
                     /protein_start="30"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVTH"
ORIGIN
        1 cggcacgacc acactcgtca ccgtcaggtc gaacgccagc gacgaatgca gcggagcacc
       61 accagccgca ccataggagc cggccgccca ctgggcatag ttggcaagcc caccgtgcgt
      121 gacggccacg cccttgggac gacccgtcga gcccgacgta tagatcacat acgccagacc
      181 gtccgccgac acggacacct cgggagcggt gtcctcaagc atcgacaact ggacgcccat
      241 cagcgtggag tccagcgcga ccatccgcgc acgacccgcc ggaagatcac ccaggatctc
      301 ctcgtccgtc agcgtcaaca ccgcaccact gtccgcgagc atgaacgaga tccgatccac
      361 cggataacca ggatcgatcg gcaggaacgc agcccccgcc ttccacaccg cgagaatcgc
      421 caccacggca tccacgccac gcggcaggca cacacccacc accgactccg cacccacacc
      481 ctgacccacc aggaaccgcg ccagccgatt cgcccgcaca tccaactccg cgaacgaaac
      541 ctccaccccg tcatcgacca cagccaccgc atccggagcc cccaccaccc gcgccccgaa
      601 caaccccggc accaaacccg aaccgaaatc ggcccccgtc gcgttccact ccgtcacgac
      661 ccgacgacgc tcgtccccat cgaggacgtc caccgcgtcc agggacaggc ccgggtcgtc
      721 ggcgaccagt tccagtacgc gcaccaggcg ctcggcgatc cgcccgacgc tccccgcctc
      781 gaagaggtcc gcggcgccga gcagcgtccc ggtcacaccc gcgggagcgc cggaggcgtc
      841 gaacacctcg cccagcagga cgtccaggtc gaaccgggca gcggcagcgg cggaggcgct
      901 ctccggtgcg ccgcccgcac ccaggcccgg caggtccagg accgcctgcg cggtgttctg
      961 catggtgaac atcgtctgga tcagcggatg gcgccccatc acacgcgccg gggccagctc
     1021 ctcgaccagc ttctcgaacg gcacgtcctg gttctcgaac gcggacaggg cggtgtcgtg
     1081 cccctgggcg agcagctccc ggaacgtcgg cgtgcccgac aggtccgtgc gcagcaccag
     1141 gctgttgacg aagaacccga ccaggtcgtc gagcgccacg tccgtgcggc ccgcgacgac
     1201 cgtgccgatc gggatgtcgg ttcccgctcc gaggcgggac agcaggaccg ccagagcgga
     1261 ctgcagtacg acgaagaggc tgacgccttc ggtccgggcg agttccgcga gcttcgcgtg
     1321 cagctcagcg ggcacctcga tcggcgcggc gagactgcgg tgcgagggca ctgcggggcg
     1381 cgggtggtcg acggggagcg tgagttcctc cggtgctccc gccagggcat tgcgccagaa
     1441 cccgagctga cgggtcatca cgctctcggg atcgtcctcg tcgccgagca gttcgcgctg
     1501 ccagagcgtg tagtccgcgt actgcacggg cagcggctcc cactcggggg cgcggcccgc
     1561 gcggcgggcc gtgtacgcca ccgagacgtc ccgggccagc gggcccatgg accaaccgtc
     1621 gcccgctatg tggtggacca ccacggccag gacgtgctcg tccggggcgg tggtgaagag
     1681 ccaggcccgg atcgggacct cggcggccag gtcgaagagg tggcgcgcgg caccggccac
     1741 ggcgtcgtcc agatcttccg ggggcatctg gacaaccgac agctcccact cgagctcgtc
     1801 gagcttgcgg atgcgctggt acggctggcc gtccttgatc gggaaaacgg tgcgcaggac
     1861 ctcgtggcgg cgcatcacgt cgcgcagcgc cgcgttcagc gcggcggggt ccagctcgcc
     1921 ggtcaggcgt cgcacgatcg ggatgttgta ggccgggctg ggtccgtcca gctgaccgat
     1981 gaaccagagc cgacgctggg caaaggacag agggatcatc agtactcctc gttggtacgc
     2041 atcggccgca gtgcgggcct ggctgtcttc tgtgttccga gttgccgggc cactccggcc
     2101 acggtcggcg tcttgtagag ggcgcggagc gagaagtcga cccgcagcag cgccctgatg
     2161 tggctgatca gccgggtggc gagcagggag tgcccgccga gggcgaagaa gtcgtcgtcg
     2221 acgcccacgc gctcgagccc cagtacctcg gcgaatgcct ggcagagcag ctcttcctgc
     2281 cggttcgccg gggcccggcc ctcgcccgag gtgtactccg gggcgggcag tgccttccgg
     2341 ttgagcttcc cgttggcggt caggggcagt gcgtgcaggg gcacgactgc cgaggggacc
     2401 atgtaggagg ggagctggtc ctggaccgcc gcccggagtg actgggcgaa cccttccggg
     2461 ggttcctccg ctccttcgac ggggaccacg taggcgacca gccgctggtc gcccggcttg
     2521 tcctcgcgga cgatcacgac ggcccgggcc acccagtccc gagcggcgag aaccgcttcg
     2581 atctcgccgg gttcgatgcg gaagccgcgg accttgacct gctcatcggc ccggcccagg
     2641 cactccagac gcccgtcgcc catccaccgc gcgagatcgc ccgtacggta caaccgctca
     2701 ccggccccac cgaacggaga agccacgaac cgctccgccg tcaaccccgg acgacccgca
     2761 taaccccgag ccaactgagc acccgacaaa tacagctcac ccgccacacc agccgggacc
     2821 ggccgcatcc aaccatccag gacatacgcc gccacatccg cgaacggccg ccccaccaac
     2881 accggaccag cagcaacctc ctccgacgtc gcccacaccg tcacctccgt cggcccgtac
     2941 aggttcaccg cacccacacc cagatccgtg aaccgctgcg ccaactccgg cggcaacgcc
     3001 tcaccaccca ccagggcacg cacccccgcc ggccaaccca cctcctccag cagcccacgc
     3061 cacagcgacg gcacaccctg caccaccgaa gcacccgacg acaccaccag ccccgtcaac
     3121 gccgccggat cacgaaccac ctcacgggaa gccaccacca ccgacgcacc cgacaccagc
     3181 ggcaggaaca actccaacgc cgcaatgtcg aacgacaccg tggtcaccgc caccagccgg
     3241 tcccccgcca ccaacggcac ccgctcaccc acaccacaca aatgcgccga caacgcaccg
     3301 tgcgacacca ccacaccctt cggacgcccc gtcgaccccg acgtatagat caggtatgcc
     3361 gggtgttccg ggagggacgt gcggcggatg ccggcggagg gttcgtgctc atccggtcgt
     3421 gcgagctcgg cgaccgtctc ggggtcgtcg agggcgacga tggcgacccc gaggtcctcc
     3481 agccagccgg tgggcccctg cgcggtgagc accagggcga ctccggcgtc gccgatcatg
     3541 taggcgaccc ggtccgccgg gtattccggg tccatcggca ggtacgcgcc tccggccttc
     3601 atcaccgcga gcagcgcgac caccagctcg accccgcggt ccagggccac gccgaccacg
     3661 gactcggggc cgacgccccg gcggttcagg taccgggcca gccgctcggc gcgggcgtcc
     3721 agttcggcgt acgacacttc cacaccctcg gacacgacgg ccgtcgcgtc gggggcgcgg
     3781 gcgacctgcg ccgcgaacag ttccgttacg ggaaccgtgg cgacgccgtc ccggccggtg
     3841 tcgttccact cgtcgaggat gcggtgcagg tcgtcctcgc cgagtacgcg taccgcagcc
     3901 agcggctgct ccggtccccc gtcgagttct ccctccaggg ccgcgaccag gttctccgtc
     3961 gcggtgcaca tgagccgtac gacggcgtgc acgtcgatgg agtgcaccgc gtccacggtc
     4021 agctccaggg agtcggcgtt gtcgtccacc gccaccacga gcggatagtt ggtgcgttca
     4081 cgggcgtacc gcagctccag accctcgaac ccgcggttgc gttcggcgtc cgcagcctgg
     4141 cccgatccgc ccgcattgtg gcggtagttg aagatggcgg tgaagagcgg tgtgtctccc
     4201 gccagtccac tggcccgctg ggccagtgcc agcgaggcgt gttcgtgctc cagcagctcc
     4261 gccagctgga ggcgcatcgc gccgacggct gccagcgctc ccagttcggc ggtccgtacc
     4321 cgcaccggca gggtgttgat gaacggtccg gggacccggt cggcgccggc gccggagttc
     4381 atcctgccga agagcaccgt cccgaacacc acgtcggtac gggccgacac ggccgccagc
     4441 gtccgtgccc acgccacgtg cagtacggtc gcggcgctgg tgcccagccg gtgggagacc
     4501 tcgcgcagtc gtgtgtgcag ctccggcccg aggggcttgc gcacccagac cgtgtccccg
     4561 ccgtcgccgt ggacgtcgac caggccgaac ggcgcggtcg gctcgtcgac gtcgccgagc
     4621 agttcggtga agtagcgctc gtgttcctgc tccgccacgc cgccgcgggc ctgtgcgacg
     4681 aagttgcgca ggggcaccgg ctccggcagc ccctcgtcct cgcccgtcat gaacgcctgg
     4741 acttcgctgt gcaacacctc cagagccacg tggtcctgga cggcgtggtg caccttgagc
     4801 agcatcagcc agtggtcgct gccgggtacc gcggcgatgt gcagcgtgaa cagcggggcc
     4861 cggcccaggt ccatcgacgt gccgccgatc gccagcagct gctcgaccgg atcggcgccg
     4921 tccgcgtcca gggacacctc ctcgacggag agcggggccc gccgccagac cacctgcacc
     4981 ggttcgcgca gcccctccca caccagcgag gtgcggaaga tgtcgtgccg gtccagcacc
     5041 tgctggagtg cccgggcgaa ctcctccagc cgttcgcgcg agacgagttc gaacacctcc
     5101 ttgctcacgt aggcgtcctc accgccgtcg gccagcatgt ggtggaagag caggccttcc
     5161 tggagcgggg ccagcgggta gacatcggcg atgttcgccg ccccgccggg aacggtcgcc
     5221 accaccgtgg ccacttcctg ctccgacagc gtgaccagcg gcagcatgtc cggcgtgatc
     5281 tccgtcgcgc cggcggggat caggttcgcc ggtacgtcga cctgcaccgc accggtggag
     5341 gccgcgagtc cggccggggt cggcgactgg aacagcgttc gtaccgagac cgacacaccg
     5401 ttgtcgcgga gcacctcgac cagccgcacc acgagcaggg agtgcccgcc gagccggaag
     5461 aagtcgtcgt cgacaccgac gctctccagg cccagcacct cggcgaaggc cgcgcagacg
     5521 atctcctctc gggcgttcgc cggagcgcga ccaccacccg ccgcgtaggc aggcgcgggc
     5581 agcgccttgc ggtccagctt cccgttgacg gtcatcggca gcgcgtccag caccaccacc
     5641 gcggacggga ccatgtacgc gggcagtcgc tcggcggccg aacggaggat cggttcgggc
     5701 agttcgccgg gcgcgccgtc gccgaccacg taggcgacca ggcgcttctc gcccggggtg
     5761 tcctcgcgga cgacgaccgc ggcctgcgtg acccgcggat gcgcggccac cacgttctcc
     5821 acctcgccgg gctcgatccg gaagccacgg atcttgacct ggtcgtcggt gcggcccgcg
     5881 aacacgagct gtccgtcggc cgtccaccgc gcccggtcgc ccgtgcggta cagccgctcg
     5941 cccgccccgt ggaacgggtt cgccacgaac cgctccgcgg tcagtgccgg acggcccagg
     6001 tacccgcggg ccagacccgc accggccacg tacagctcac cggcgacacc gaccggcacc
     6061 ggcgccagga actcgtccag cacgaacacc cgggtgttca ccacgggtgc gccgatcgcc
     6121 acctcgtcgg cggtctccgg gtcgacggac cagcaggtgg catccaccgt ggtctcggcg
     6181 gggccgtagg cgttgaacat ccggcggccc gccgcccagc gcgccgcggt ctcggggggc
     6241 agggcctcgc ccgccgtcac cagggcgagg tccttggaga ccgtgttctc gtcgagggtc
     6301 accagtaccg cgggcggcag cgtcacatgg gtcactgcct gctcggtcag gaactgtgcc
     6361 aggtcgttgc cgacccgccg gtccggcggg atcaccacca gggtcgcccc ggtcagcagg
     6421 gccatgaacc attcccaggc gaaggcgtcg aagccgatcg aggcgaactg cccgacccgg
     6481 tgtccggggc ccacgcccag cagcgcggtg tggcccgcgg tcatgctcgc cacaccggcg
     6541 tgcgggacga ggacgccctt cggccgtccc gtcgaacccg aggtgtagat cacgtacgcc
     6601 gggtgcgcca ccgactgccc cgcgagccgc ggtgcaccgc cgtccagacg gcccagggcc
     6661 gccacgacct cggggtcgtc cagcagaacg gcgcccggga gcacggcctc ggtcgcggcc
     6721 gaggccaaca ggacccgggg ctccgcgtcc cgcagcatgt acgcgacccg ctccgccggg
     6781 tactcggggt cgaccgtcat gtaggcgccg ccggccttca gtacgccgag caccgcgacc
     6841 agcagttcga cgccccggtc caggcacacc gcgaccaggg actcggggcc cacgccccgc
     6901 gacgccaaca ggcgagcgag acggttcgcc cgggcgtcga gctccgcgta cgagacctcc
     6961 accccgtcgg cgaccacggc cacggcctgc ggagcgcggt acacctgcgc ggcgaacagg
     7021 tccgccgccg tccgcggctc gatgtcgagc gccgtgtcgt tccattccac gagcatccgg
     7081 cgcgaggtgt cctcgtcgag gacgcccagc gcgcccagcc gctgctccgt cccgccgtcg
     7141 agtgccgtct ccaaggcggt gaccaggttc tcggcgacgg accgcatcag ttctccgacg
     7201 gcctcgccgt cgatgacgga gacggcgtcg acggccagcg cgatcgactc cccgtcgtcg
     7261 tccacggaca ccgcgagggg gtagttggtg cgttctcgcg agtggaccgc cgtgaagccc
     7321 tcgaagccgc gcgtacggtc gtcgttcgcc ccggtcgcgg aaccgggcgc gttgtggcgg
     7381 tagttgaaca gcgcggtgaa cagcggtgca tctccttgca gtccgctggc gcgctgggcc
     7441 tgggccagcg aggcgtgctc gtgttcgagc agctccgcca gctgaccgcg catcgcgtcc
     7501 acggcctcca gcacccccag ggcgcccgta cgcacccgca ccgggagcgt gttgatgaac
     7561 gggcccggca tgtccgccga tcccgcgccg gagttcatcc gtccgaagag caccgtgccg
     7621 aacacgacgt cgccgcggcc cgacacggcc gccagggtcc gcgcccacgc cacgtgcagc
     7681 accgtcgccg cgctggtgct cagccgggcc gagaccgccc ggagccgcgc atgcagctcc
     7741 ggcgcgaagg gcacgtgcac gcgtgtcacg tccgctccgt cgcccagcac gtcgaccagg
     7801 ccgaagggtg cggtgggctc ctcgacgtcg ccgagcagct gcgtgaagta ccgctcgtgc
     7861 tccgagcgtt ccgcgccgcc acgggcctgt gccacgaagt tgcggaacgg caccggctgc
     7921 ggcagcgagt caccgcgccc ggtcaggaac gcctgcacct cgccgaggac cacttccatc
     7981 gcggtgtggt cctgcacggc gtggtgcacc ttgagcagca tcagtcggcg gctgctgccg
     8041 ggtaccgcgg cgacgtgcat cgtgagcagc ggcgcgcggc ccaggtccat cgacatcccg
     8101 ccggccgcga gcagttggtc cacgggctcg gcgccgtgcg cctccagcgt cacttgctcg
     8161 acggagagcg gggcccgccg ccggaccacc tgcaccggtt cgcggactcc ctcccacacc
     8221 agggaggtgc ggaagatgtc gtgccggtcg atcacctgct gcagcgcccc ggtgaactcc
     8281 tccagcagtt cagccgattc gacttcgaag acgaccgggg tcacgtaggc gtcctcacca
     8341 ccgtcggcca ggacgtggtg gaagaccagt ccctcctgga ggggtgccag tgggtagacg
     8401 tcggccacgt tcgcggcgcc gccggggacg gtcgcgacga tccgggcgac ctcctcggtg
     8461 gtcaggtcga cgagcggcag catctccggg gtgatctcca ccgcatcggc ggggatcagg
     8521 ttcgccggga cctccagcgc acgggcggag cccgtcggca gggcgagccc ggccggggtg
     8581 ggcgtctgga acagcgcccg taccgacacc ggcacgccgt tcgcgcgcag cacctcgacc
     8641 agccgcaccg cgagcaggga gtgcccgccg agctggaaga agtcctcgtc gacgccgacg
     8701 ctcgcgaccc ccagcacctc ggcgaaggcc gcgcagacga tctcctctcg ggcgttcgcc
     8761 ggagcccggc cgccaccggt cgcatagacg ggtgcgggca gggccccccg gtccagtttc
     8821 ccgttcaccg tcaacggcag ctcgtccagc agtaccaccg ccgagggggc catgtaggcg
     8881 ggcagccgct cggcggccag ccgcgtcagc gcctcgggca ggtctccccg cgcgccgtcg
     8941 gcgaccacgt aggccaccag tcgccggtct cccggcgcgt cctcgcggac gatgaccgcg
     9001 gcctgcgtga cccgcggatg cgagtccagc acgttctcga tctcacccgg ctcgatgcgg
     9061 aaaccgcgga tcttgacctg gtcgtcggtg cggcccgcga acacgagctg tccgtcggcc
     9121 gtccaccgcg cccggtcgcc cgtgcggtac agccgctcgc ccgccccgtg gaacgggttc
     9181 gccacgaacc gctccgcggt cagtgccgga cggcccaggt acccgcgggc cagacccgca
     9241 ccggccacgt acagctcacc ggcgacaccg accggcaccg gcgccaggaa ctcgtccagc
     9301 acgaacaccc gggtgttcac cacgggtacg ccgatcgcca cctcgcccgc ctccgggtcg
     9361 cagcgccaca gcgtcgcgtc gaccgtggtc tcggccggtc cgaaggagtt gaacagccgg
     9421 tgaccacgcg cccagcgcgc catcacctcc ggcggcagcg cctcgccgcc cgtcaccagg
     9481 acgacgtccc cgccgatgga gtcctcgtcc agggtggcca ggaccgcttg cggcagcgcc
     9541 acgtgggtca cggcccgttc ggccaggaac gccggcaggg cctcgccgag gcgctgctcg
     9601 tgcgggatca ccaccagggc ggcgccggtc agcagggcca tgaaccactc ccacgcgaag
     9661 gcgtcgaagc ccacggaccc gtactggccc acccgggcac cggcgccgac acccaggtac
     9721 cggctctggc ccgccaccag gctcgccaca cccgcgtggg agaccaccac gcccttcggg
     9781 cggcccgtcg atcccgacgt atagatcacg taggcggcgt cctgtgcccg caccaccacg
     9841 tccagcaggc caccgtccag gtccgcgacg gccaggtcgt ccaccagcag cgcgtccggc
     9901 gcgagtctcc gcgtaccggc cgaggccagc acgaccaccg gcgacgcgtc ctccagcatg
     9961 tacgcgacgc gctgcgccgg gtactccggg tcgatcgtca tgtaggccgc accggtcttc
    10021 accaccgcga gcaccgcgac cagcaggtcg acaccgcggt ccaggcagac gcccacgacg
    10081 gaaccggccg tcacgccccg gcctaccagg taccgggcca accggttcgc ccgcgcgtcc
    10141 agctccgcgt acgacacctc cgcgccgtcg gcgaccacgg caacggcctc cggggtccgc
    10201 gccacctgcg ccgcgaaaag ctccggcacc gaggccgaag cgacctcgga ccccgtgtcg
    10261 ttccaccgca ccagcatccg gtgccggtcc tcgggagtca gtacgtggac ggtgcgcagc
    10321 gccgtgtccg caccgccgtc cagggcctgt tccaccaggg gcaccagggt ctcgacggcc
    10381 tcccgcagca gcagcccgac ggcctccgcg tcgatcggcg cgaccgcgtc cacggcgaac
    10441 gacatcgagt cgccgttgtc gtcgacggac acgccgagcg ggtagttcgt gcgctcccgc
    10501 gaggacagca tccgcatgcc ttcaggacgg gcgtagccct ccttctcggc ctccgcaccg
    10561 gtgttgtggc ggtagttgat cagtgaggtg aatacggggg ttttgccggc gaggccactg
    10621 gcctgctggg ccagggccag cgaggcgtgc tcgtgctcca gcagcccggc cagctggccg
    10681 cgcatcgcgg tcaccgcctc gagcgcgccc agttcacccg tgcgcacccg caccgggagc
    10741 gtgttcaggt agagcccggc cacccggtcg gcgcccgcgc ccgcgttcat ccggccgaac
    10801 aggaccgtgc cgaacacgac gtccgagtgc cccgacaccg cggcgaggac ccgcgcccac
    10861 gccacgtgca gcaccgtcgc cgggctcgtg ccgaccctcc gtgccacggc gcgcagccgc
    10921 tccagggact ccggcgcgag cggcaccacg gcacgctcca catcggtgcc gtcaccgcgt
    10981 acgtcgacca gcccgtaggg ggccgtcggc tccgtcacgt cgccgagcag ctcggcgaag
    11041 taccgctcgt gctcggcccg gtccacaccg ccgcgcacct gcgcgacgaa gtcacggaac
    11101 ggcagcggcc ggggcagttc gtcgtcacgg ccggccagga acacctgcac ctcgtgcagg
    11161 agcagttcca gcgcggtgtg gtcctgcacc agatggtgca ggcgcagcag caccagccag
    11221 cgcttcccgt ccggcagcgc cgccgcgtgc acgctgacca gcggcgcccg gctcaggtcc
    11281 atcgacaatc ccacggccgc ctgcagcgcg gcggcggggt ccgcagccgc ggggtccagg
    11341 tccacctcga tcacgggcag cacggccttg cgccacacca cctggaccgg ctcgcgcagc
    11401 ccctcccaca cgaaggacgt ccgcaggatg tcatgccggt ccacgaccag ctggaaagca
    11461 cgggcgaact cctccacccg ctcccgggag tccatctcga ccaccacggg catcaggtag
    11521 gcgtcctcgc caccctccgc catcaggtgg tggaagagca ggccctcctg cagcggcgcc
    11581 agcggataga tgtccgccac gttcgccgcg ccaccgtcca cggtggagac gattcgctcg
    11641 acctcgtcca cggtcaggtc gaccaggggc agcagttcgg gggtgatctc caccgcgtcg
    11701 gcgggaatca gattcgccgg cacgacggac tcgatcgtgc ccacggagag cgcgagaccc
    11761 gccggggtcg gggtgtcgaa cagggcgcgg accgagaccg acaccccgtg cttgcgcagg
    11821 acctcgacca ggtggaccgc aagcagggag tggcctccca gggcgaagaa gtcgtcatcg
    11881 acgcccgcgc tctccagacc cagcacttcg gcgaacgccg cgcacaggat ctcttcgcgc
    11941 tcgttggccg gcgcgcgtcc cgtacccgcg cccgccagtt caggggcggg cagggccttg
    12001 cggtccagct tcccgttccc ggtcaacggc agcgcctcca gcaccaccac ggccgaggga
    12061 accatgtact ccggcagccg gcccgagacg aacgcgcgga ccagcccggg cagtgcggcc
    12121 agatcgtcat ccggatcgtc ggcaacgacg tacgcgacca gacggacatc gcccggcacg
    12181 tcctcacgcg ccaccaccgc aacctgcgcg acctgcgggt gcccggccac cacggcctgg
    12241 acctcacccg gctcgatccg gaaaccacgc accttcacct gctcgtcagc acgccccaag
    12301 aactccagct gaccatccac acgccaacga gccaggtcac ccgagcggta catccgccca
    12361 ccacgctcga acgggctcgc cacgaaccgc tccgccgtca gctccggacg ccggacataa
    12421 ccacgggcca gctgagcgcc cgcgatatac aactcacccg ccacacccgg agcaaccggc
    12481 cgcagaaaac catccaggac ataaagctgc gtgttcgcca ccggacgacc gatcgggacc
    12541 acgtcaccga tctcatcacc ggcacggacc tcgaacaccg cacacccgac gaccgtctcc
    12601 gtcggaccgt actcattgac gaccaccgag ccaggagcac gctccagcca cgcctgcacc
    12661 accgaacccg acagcgcctc accaccgacc acccacgtcg acaccgcacc cttcacttcg
    12721 ccgtccgtga gcatctccga cagcaaggga aggtgcgccg gcacagcctt cgtcagaccg
    12781 aaaccaccac catcgcgcaa cagctcggcc aggccctcgg caccgccctc acgactcacc
    12841 accaccggcg cacccgaaat cagcggcacg accacactcg tcaccgtcag gtcgaacgcc
    12901 agcgacgaat gcagcggagc accaccctcg gcggcgccgt atgaacgagc agcccactgc
    12961 gcatagttgg caaggccacc gtgcgtgacg gccacaccct tgggacgacc cgtggaaccc
    13021 gacgtataga tcacatacgc cagaccctcg gaacgggtca ccacctcggg agcggagtcc
    13081 tcaagcatcg acaactggac acccatcagc gtggagtcca gcgcgaccat ccgcgcacga
    13141 cccgccggaa gatcacccag gatctcc
//
