LOCUS       NZ_BMVL01000013        24783 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence13, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000013
VERSION     NZ_BMVL01000013.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 234149)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 24783
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24783
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..24783
                     /SMILES="NC(CC(=O)N)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24783
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:4783](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..4783)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(<1..4783)
                     /locus_tag="IE257_RS28465"
     CDS             complement(<1..4783)
                     /NRPS_PKS="Domain: Condensation_Starter (2-292). E-value:
                     3.7e-73. Score: 238.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS28465_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (451-849). E-value: 3.4e-98.
                     Score: 320.9. Matches aSDomain:
                     nrpspksdomains_IE257_RS28465_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (957-1024). E-value: 1.1e-25. Score:
                     81.6. Matches aSDomain: nrpspksdomains_IE257_RS28465_PCP.1"
                     /NRPS_PKS="Domain: Condensation_Dual (1071-1361). E-value:
                     1.2e-105. Score: 345.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS28465_Condensation_Dual.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="IE257_RS28465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_189972748.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-107, bitscore:
                     353.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.2e-15, bitscore:
                     49.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.4e-44, bitscore:
                     145.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMAGQLAIWYSHQLAPENPCFNGAEYLALDGDVDLGLLVKASQRL
                     MEEADAARLRIREVDGQPRQYFHDVEDYPVEVIDISAEADPQAAAEGLMWEDLRSERGA
                     ADRSLYTIKIYTAGPRLTFWYQRAYHVILDGRSAGLVVGRLSQVYNTLLQGGSVEEGAL
                     PSSTVLMDAEREYRASDAHATDRDYWRGVLAGLPEAEGPGSNYAGRAQRAPVRFVESVD
                     DTVGADLKAAARGLGTNFAGLMISAAALYQHHLTGQRDVVVGVPVSGRSGTRDLAIPFM
                     TNNVLPIRVKISPDTSVADLVRQTTRAVMKGLRHQRYRYEHMLNDAMLGEGGLWDLLIN
                     VMSFDIYALPFGDCTVTAHNLSSGPVDSTRIDVYDRSGLKIAVDVNPDAPDLSPGDEVC
                     RRFLALAHWLVSVDPAEPVGRSGLLDADERRQVLVEWNDTATQFAGHSVPELFAAQAAR
                     TPDAAAVIADGVEVSYAELDERANALARYLVGQGVTVESVVGVCLPRSADAVVAILAAW
                     KAGAGYLPIDPDHPVDRIAYLLADSGAVVTLTDSAARAARLTGTAHVVTLADALASGTV
                     TAEPATVPAAPAAADGLAYVIYTSGSTGRPKGVAVTHRGLANYAQWAAGAYGAGAAPLH
                     SSLAFDLTVTSIVIPLISGAPVVVSREGSAEGLAELLRGHGGYGLAKVVPAHLPLLTEM
                     LTESQIEAAASTWVVGGEALPGSVVQSWLEHAPGSVIVNEYGPTEAVVGCCVFEIRAGQ
                     VVGEPVPIGRPIANMRLYVLDSFLCPVAPGVAGELYIAGVQLARGYVDRAGLTAERFVA
                     NPFEAGARMYRTGDVARRRTDGELEYLGRADEQVKVRGYRIEPGEVQAVIAAHPQVAQA
                     AVIAREDTPGDVQLVAYVVTDEDVEDLTEQVLAFATEQLPEHMVPSAVVVLDALPLAMS
                     GKLDRKALPAPDFGTRAGTGRGPSNAREEILCAAFADVLGLERVGVDDNFFQLGGQSLM
                     AIRLVGAIRKLGVSVSVRAFFDSPTPAGLAASVGASAIEVPANLIPADATAITPEMLPL
                     VDLSADEVARVVATVEGGAANIADVYPLAPLQEGLLFHHLLADGEEDTYVACAVLEFDS
                     AERVDSFADALQQVLDRHDIFRTAIAWEGLPQPLQVVRRRAELPVTEVVIDPHAADPVA
                     ELPAVVGRAMDIRRAPLLGLHVATVTDGRRLVLLRLHHLVQDHTTVEVLLSEIREFMGG
                     RGAELPQPLPFRDAVVQTRAGLADGGHEQFFTDLLGDVTEPTAPFGLLNTREPGMKSRE
                     TEVRIAADLERRLRRVARKVGASPATLMHVAWARVLAAVSGRDDVVFGTVLFGRMGADA
                     DEARVLGPFMNMLPVRVKTGQLGVMGAVSAMRRQLAALMEHEHAPLAVAQNASGVEGEA
                     PLFASMFNYRHNDRSVSKSGALFDGVELRLYREQTNYPLAVNLDDDEDGMRLTVDAAAP
                     ADPRQVGTLLCTATRNLLTALERAAAGGPELALGAVEVLDAAERRQVLVEWNDTAVEVE
                     PSSLPGLFEAQVGRTPGAVAVVFEGVEHSYAELDARANRLARLLLSRGVTTGSVVGVRL
                     ERGVELVVALLAVLK"
     CDS_motif       complement(590..652)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0015"
                     /evalue="6.30E-09"
                     /label="C67_dual_14fromHMM"
                     /locus_tag="IE257_RS28465"
                     /protein_end="1398"
                     /protein_start="1377"
                     /score="28.3"
                     /tool="antismash"
                     /translation="LAALMEHEHAPLAVAQNASGV"
     aSDomain        complement(701..1570)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS28465_Condensation_Dual.
                     1"
                     /domain_subtypes="Condensation_Dual"
                     /evalue="1.20E-105"
                     /label="IE257_RS28465_Condensation_Dual.1"
                     /locus_tag="IE257_RS28465"
                     /protein_end="1361"
                     /protein_start="1071"
                     /score="345.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLVQDH"
                     /tool="antismash"
                     /translation="DVYPLAPLQEGLLFHHLLADGEEDTYVACAVLEFDSAERVDSFAD
                     ALQQVLDRHDIFRTAIAWEGLPQPLQVVRRRAELPVTEVVIDPHAADPVAELPAVVGRA
                     MDIRRAPLLGLHVATVTDGRRLVLLRLHHLVQDHTTVEVLLSEIREFMGGRGAELPQPL
                     PFRDAVVQTRAGLADGGHEQFFTDLLGDVTEPTAPFGLLNTREPGMKSRETEVRIAADL
                     ERRLRRVARKVGASPATLMHVAWARVLAAVSGRDDVVFGTVLFGRMGADADEARVLGPF
                     MNMLPVRVK"
     CDS_motif       complement(707..802)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0014"
                     /evalue="2.60E-10"
                     /label="C5_dual_260-291"
                     /locus_tag="IE257_RS28465"
                     /protein_end="1359"
                     /protein_start="1327"
                     /score="32.9"
                     /tool="antismash"
                     /translation="DVVFGTVLFGRMGADADEARVLGPFMNMLPVR"
     CDS_motif       complement(812..868)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0013"
                     /evalue="2.50E+00"
                     /label="Cy4"
                     /locus_tag="IE257_RS28465"
                     /protein_end="1324"
                     /protein_start="1305"
                     /score="1.6"
                     /tool="antismash"
                     /translation="ASPATLMHVAWARVLAAVS"
     CDS_motif       complement(1124..1177)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0012"
                     /evalue="3.40E-05"
                     /label="C3_dual_135-156"
                     /locus_tag="IE257_RS28465"
                     /protein_end="1220"
                     /protein_start="1202"
                     /score="16.8"
                     /tool="antismash"
                     /translation="HHLVQDHTTVEVLLSEIR"
     CDS_motif       complement(1382..1495)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0011"
                     /evalue="2.50E-15"
                     /label="C2_dual_024-063"
                     /locus_tag="IE257_RS28465"
                     /protein_end="1134"
                     /protein_start="1096"
                     /score="49.0"
                     /tool="antismash"
                     /translation="YVACAVLEFDSAERVDSFADALQQVLDRHDIFRTAIAW"
     CDS_motif       complement(1523..1564)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0010"
                     /evalue="9.30E-07"
                     /label="C1_dual_004-017"
                     /locus_tag="IE257_RS28465"
                     /protein_end="1087"
                     /protein_start="1073"
                     /score="21.1"
                     /tool="antismash"
                     /translation="YPLAPLQEGLLFHH"
     aSDomain        complement(1712..1912)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS28465_PCP.1"
                     /evalue="1.10E-25"
                     /label="IE257_RS28465_PCP.1"
                     /locus_tag="IE257_RS28465"
                     /protein_end="1024"
                     /protein_start="957"
                     /score="81.6"
                     /tool="antismash"
                     /translation="EEILCAAFADVLGLERVGVDDNFFQLGGQSLMAIRLVGAIRKLGV
                     SVSVRAFFDSPTPAGLAASVGA"
     aSModule        complement(1712..4777)
                     /complete
                     /domains="nrpspksdomains_IE257_RS28465_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_IE257_RS28465_AMP-binding.1"
                     /domains="nrpspksdomains_IE257_RS28465_PCP.1"
                     /locus_tags="IE257_RS28465"
                     /monomer_pairings="Asn -> Asn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1874..1906)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0009"
                     /evalue="2.00E-02"
                     /label="Cy4"
                     /locus_tag="IE257_RS28465"
                     /protein_end="970"
                     /protein_start="959"
                     /score="8.1"
                     /tool="antismash"
                     /translation="ILCAAFADVLG"
     CDS_motif       complement(2210..2272)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0008"
                     /evalue="2.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS28465"
                     /protein_end="858"
                     /protein_start="837"
                     /score="35.5"
                     /tool="antismash"
                     /translation="YLGRADEQVKVRGYRIEPGEV"
     aSDomain        complement(2237..3430)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS28465_AMP-binding.1"
                     /evalue="3.40E-98"
                     /label="IE257_RS28465_AMP-binding.1"
                     /locus_tag="IE257_RS28465"
                     /protein_end="849"
                     /protein_start="451"
                     /score="320.9"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="FAAQAARTPDAAAVIADGVEVSYAELDERANALARYLVGQGVTVE
                     SVVGVCLPRSADAVVAILAAWKAGAGYLPIDPDHPVDRIAYLLADSGAVVTLTDSAARA
                     ARLTGTAHVVTLADALASGTVTAEPATVPAAPAAADGLAYVIYTSGSTGRPKGVAVTHR
                     GLANYAQWAAGAYGAGAAPLHSSLAFDLTVTSIVIPLISGAPVVVSREGSAEGLAELLR
                     GHGGYGLAKVVPAHLPLLTEMLTESQIEAAASTWVVGGEALPGSVVQSWLEHAPGSVIV
                     NEYGPTEAVVGCCVFEIRAGQVVGEPVPIGRPIANMRLYVLDSFLCPVAPGVAGELYIA
                     GVQLARGYVDRAGLTAERFVANPFEAGARMYRTGDVARRRTDGELEYLGRADEQVKVR"
     CDS_motif       complement(2354..2440)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0007"
                     /evalue="7.70E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS28465"
                     /protein_end="810"
                     /protein_start="781"
                     /score="47.0"
                     /tool="antismash"
                     /translation="PGVAGELYIAGVQLARGYVDRAGLTAERF"
     CDS_motif       complement(2945..3004)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0006"
                     /evalue="9.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS28465"
                     /protein_end="613"
                     /protein_start="593"
                     /score="33.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVTH"
     CDS_motif       complement(3203..3244)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0005"
                     /evalue="4.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS28465"
                     /protein_end="527"
                     /protein_start="513"
                     /score="13.8"
                     /tool="antismash"
                     /translation="LAAWKAGAGYLPID"
     CDS_motif       complement(3767..3865)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0004"
                     /evalue="8.10E-08"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="IE257_RS28465"
                     /protein_end="339"
                     /protein_start="306"
                     /score="24.8"
                     /tool="antismash"
                     /translation="RAVMKGLRHQRYRYEHMLNDAMLGEGGLWDLLI"
     aSDomain        complement(3908..4777)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS28465_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="3.70E-73"
                     /label="IE257_RS28465_Condensation_Starter.1"
                     /locus_tag="IE257_RS28465"
                     /protein_end="292"
                     /protein_start="2"
                     /score="238.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: YHVILDG"
                     /tool="antismash"
                     /translation="AGQLAIWYSHQLAPENPCFNGAEYLALDGDVDLGLLVKASQRLME
                     EADAARLRIREVDGQPRQYFHDVEDYPVEVIDISAEADPQAAAEGLMWEDLRSERGAAD
                     RSLYTIKIYTAGPRLTFWYQRAYHVILDGRSAGLVVGRLSQVYNTLLQGGSVEEGALPS
                     STVLMDAEREYRASDAHATDRDYWRGVLAGLPEAEGPGSNYAGRAQRAPVRFVESVDDT
                     VGADLKAAARGLGTNFAGLMISAAALYQHHLTGQRDVVVGVPVSGRSGTRDLAIPFMTN
                     NVLPIRVKI"
     CDS_motif       complement(3917..4006)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0003"
                     /evalue="8.00E-07"
                     /label="C5_starter_265-294"
                     /locus_tag="IE257_RS28465"
                     /protein_end="289"
                     /protein_start="259"
                     /score="21.6"
                     /tool="antismash"
                     /translation="DVVVGVPVSGRSGTRDLAIPFMTNNVLPIR"
     CDS_motif       complement(4337..4396)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0002"
                     /evalue="6.70E-05"
                     /label="C3_DCL_135-156"
                     /locus_tag="IE257_RS28465"
                     /protein_end="149"
                     /protein_start="129"
                     /score="15.5"
                     /tool="antismash"
                     /translation="HVILDGRSAGLVVGRLSQVY"
     CDS_motif       complement(4610..4729)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28465_0001"
                     /evalue="4.00E-12"
                     /label="C2_starter_024-063"
                     /locus_tag="IE257_RS28465"
                     /protein_end="58"
                     /protein_start="18"
                     /score="38.7"
                     /tool="antismash"
                     /translation="PCFNGAEYLALDGDVDLGLLVKASQRLMEEADAARLRIRE"
     gene            5357..6559
                     /locus_tag="IE257_RS28470"
                     /old_locus_tag="GCM10010343_58400"
     CDS             5357..6559
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016910035.1"
                     /locus_tag="IE257_RS28470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58400"
                     /product="cytochrome P450"
                     /protein_id="WP_189972749.1"
                     /sec_met_domain="p450 (E-value: 1.9e-20, bitscore: 66.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNESADPAPQINLVDPGLYSHGDPFVQWRWLRANDPVYWHPPTE
                     LPGFWALTRYEDVRTAYRDAETFSSAQGILLRPADHGADPGGGRTLALTDAPRHRQLRG
                     LVDEWFAVRSVRALEHEMTDITRRIVDKALEQGSCDFVTDVAARVPLYVICKMMGVPES
                     DWEHLYDLTSQAFAAGDPLERRFAHLNILGYFEELQAEKAARPGDDLVSVLATGTVDGE
                     RLSPDDVILNCDNLLVGGTENTRIAAAGGMLAFLEHPDQWQLLVDEPTLLPSAVEEVMR
                     WTSTATHILRTATRKTEIHGRTIEAGDRVVFWLPSANRDETVFDSPDSFVIARKPNRHL
                     ALGFGEHFCLGSMLARVELRLLYGELLDRNVRVELDGAPTLLDSIVVNGPAKLPVKLTL
                     S"
     gene            complement(6634..6909)
                     /locus_tag="IE257_RS28475"
                     /old_locus_tag="GCM10010343_58410"
     CDS             complement(6634..6909)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_PP (5-85). E-value: 3.9e-17. Score:
                     54.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS28475_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071569.1"
                     /locus_tag="IE257_RS28475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58410"
                     /product="acyl carrier protein"
                     /protein_id="WP_189972750.1"
                     /sec_met_domain="PP-binding (E-value: 4.2e-14, bitscore:
                     46.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDITDAPATADATEVRAWLRECVATYVRLPAEDIDENLPLSEYG
                     LDSVYVLSLCADIEDRYGIEVEPTLLWDHPAIGPISEALAPLLAAR"
     aSDomain        complement(6655..6894)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS28475_PKS_PP.1"
                     /evalue="3.90E-17"
                     /label="IE257_RS28475_PKS_PP.1"
                     /locus_tag="IE257_RS28475"
                     /protein_end="85"
                     /protein_start="5"
                     /score="54.4"
                     /tool="antismash"
                     /translation="DAPATADATEVRAWLRECVATYVRLPAEDIDENLPLSEYGLDSVY
                     VLSLCADIEDRYGIEVEPTLLWDHPAIGPISEALA"
     gene            complement(6959..8707)
                     /locus_tag="IE257_RS28480"
                     /old_locus_tag="GCM10010343_58420"
     CDS             complement(6959..8707)
                     /EC_number="1.3.8.-"
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492098.1"
                     /locus_tag="IE257_RS28480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58420"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_189972751.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.4e-10, bitscore:
                     33.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.6e-11, bitscore:
                     38.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVDPAGATSPAASPDPIDRLEALFGDAGAAGNPVGREAVLAAD
                     ADGSMLAAGEDLLDAFGLNAHFVPEALGGRFAGPEELIGVMRAVYRRDPALGLGYGAGS
                     FMAAVNVWTSGSAEQQSWLAGHLLSGGRVACGYHELAHGNDFARAELTALPGPDGQLLV
                     NGRKEVVANLARAGAVVLFARTDAAAGSRSHSQLLLETARLASDTLTRLPRFATVGMRG
                     VPLGGIEFTDCPVPADAVVGTPGHGLETAQRSFQLTRIALPGMTLGLLDTALRTALRGA
                     LGRRLYAGTAADLSLSRTVLAEAFADLLLADAFVTVAARAAHTAPGQSTVYASAVKLLV
                     PALVMGAVSRLSELLGSQFYLRAAEQPLFQKLQRDVLPSAFGHASRVSCQAALLPQLPL
                     TVRRTWSAEDGPALPPTTFRPGEPLPPLDFGALKVTAGGRDPLSRSLLQGAERPTGRGE
                     DAELAARASQYATEIRALSAEAARLTPDQLGPAAPPHAFDLTTRWAGVLAAAACLGLWW
                     ERPGDGQGPGAEPAWVLAALHRLGVHTGRHHDPLPEPLSEFLYAELLRRHDAGLTFDHA
                     RRPTGA"
     gene            complement(8704..10392)
                     /locus_tag="IE257_RS28485"
                     /old_locus_tag="GCM10010343_58430"
     CDS             complement(8704..10392)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670011.1"
                     /locus_tag="IE257_RS28485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58430"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_189972752.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.1e-15, bitscore:
                     51.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.5e-16, bitscore:
                     53.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADVPEWPTGLAAALADAMAAGAAAGGAFSTARSAALDAAEAFP
                     GEECDLLDASGLARAYVPERLGGVAGGLPELLSALREVARRDVTVAVAHGKTFLGSVST
                     WVAGTEDQQRALARLVTDENAVVAWGLTERGMGSDLLAGNLTATPEPDGTWRITGEKWP
                     INNATRGRLICVLARTDPAGGPRGFSLFLIDKSALPEGAWEPLPKEPTHGIRGADISGL
                     RLRDAPVPADALVGGVGDGLGIVLRALQLTRTLCAALSLGAGEHALRLVADFAVERALH
                     GTRLALLPLARRVLGRAAASLALADAAALLGGRSAHGLPGEMSAVSATVKAGVPWIVQQ
                     AIDDLAELLGARGFLTEQHADGMFQKLERDHRIVAVFDGSTAVNRSLLISQFPLLARLI
                     RKGSYDATGLAAVTGGAPLPELDPAALRLVSRTGCSIVQAVPDTAERITALAAAGELPP
                     RAAELAALLAERTGALADAMAELPPTGRNAPAAAFAVARQFEACFAGAAALHLLAVPCA
                     ADRAVVLTAALERCLELLVPGHQAPSDAFEPLVTPLVQPVEEPVR"
     gene            complement(10389..12131)
                     /locus_tag="IE257_RS28490"
                     /old_locus_tag="GCM10010343_58440"
     CDS             complement(10389..12131)
                     /NRPS_PKS="Domain: CAL_domain (39-467). E-value: 9.3e-125.
                     Score: 408.8. Matches aSDomain:
                     nrpspksdomains_IE257_RS28490_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823563.1"
                     /locus_tag="IE257_RS28490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58440"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_189972753.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 2.9e-228, bitscore:
                     754.1, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.3e-92, bitscore:
                     302.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTREPSVLHLLRRHAVDRADRTAVTFVHDFDAADGSRSLTYAELD
                     AEARRVASWLQERCAPGDRVLLLHPAGLPFVTAFLACLYAGVIAVPSPMPGQFQYQQRR
                     VTMIARDAGVSVALTDTGQLAEAQQWISDTGLELPVAASDGPGFGDAARWRDPGATTQD
                     VVLLQYTSGSTGDPKGVMVTHGNLLHNADSLSRSLGFTEDTNFGGWIPLYHDMGLMGQL
                     LPGLFLGSSVALMSPMAFLKRPHHWLALIDRYDIGFSAAPNFAYELCLRRVTDAQIATL
                     DLSRWQFAANGSEPIQASTLRQFAERFGAAGFRAEQLAPCYGMAEATVFISGRSTRPPR
                     IRAVDPQALEKHVVQDPQPGGPVRELVGCGDVPDLDVRIVDAESGRALTDGTTGEIWLR
                     GPSVAAGYWNRPDVTEQIFHARTADGDGPYMRTGDLGVFLDGEIYVTGRTKDLLIVNGR
                     NLYPHDIEHELRLSHAPLATLAGTAFTVPAPQEEVVVVHEVRGRFTQEELRELAIGMRA
                     TVHREFGVSTAGIVLMRPGTVRKTTSGKVQRAEMRGLFLAGDLTPLYEEMAPGVRAALA
                     GATA"
     aSDomain        complement(10731..12014)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS28490_CAL_domain.1"
                     /evalue="9.30E-125"
                     /label="IE257_RS28490_CAL_domain.1"
                     /locus_tag="IE257_RS28490"
                     /protein_end="467"
                     /protein_start="39"
                     /score="408.8"
                     /specificity="Minowa: fatty_acid"
                     /tool="antismash"
                     /translation="TYAELDAEARRVASWLQERCAPGDRVLLLHPAGLPFVTAFLACLY
                     AGVIAVPSPMPGQFQYQQRRVTMIARDAGVSVALTDTGQLAEAQQWISDTGLELPVAAS
                     DGPGFGDAARWRDPGATTQDVVLLQYTSGSTGDPKGVMVTHGNLLHNADSLSRSLGFTE
                     DTNFGGWIPLYHDMGLMGQLLPGLFLGSSVALMSPMAFLKRPHHWLALIDRYDIGFSAA
                     PNFAYELCLRRVTDAQIATLDLSRWQFAANGSEPIQASTLRQFAERFGAAGFRAEQLAP
                     CYGMAEATVFISGRSTRPPRIRAVDPQALEKHVVQDPQPGGPVRELVGCGDVPDLDVRI
                     VDAESGRALTDGTTGEIWLRGPSVAAGYWNRPDVTEQIFHARTADGDGPYMRTGDLGVF
                     LDGEIYVTGRTKDLLIVNGRNLYPHDIEH"
     CDS_motif       complement(10734..10796)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28490_0003"
                     /evalue="8.50E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS28490"
                     /protein_end="466"
                     /protein_start="445"
                     /score="12.2"
                     /tool="antismash"
                     /translation="TGRTKDLLIVNGRNLYPHDIE"
     CDS_motif       complement(10878..10964)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28490_0002"
                     /evalue="2.10E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS28490"
                     /protein_end="418"
                     /protein_start="389"
                     /score="36.0"
                     /tool="antismash"
                     /translation="DGTTGEIWLRGPSVAAGYWNRPDVTEQIF"
     CDS_motif       complement(11580..11633)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS28490_0001"
                     /evalue="9.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS28490"
                     /protein_end="184"
                     /protein_start="166"
                     /score="27.3"
                     /tool="antismash"
                     /translation="LQYTSGSTGDPKGVMVTH"
     gene            complement(12268..13176)
                     /locus_tag="IE257_RS28495"
                     /old_locus_tag="GCM10010343_58450"
     CDS             complement(12268..13176)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (16-294). E-value: 2.4e-44. Score:
                     144.0. Matches aSDomain:
                     nrpspksdomains_IE257_RS28495_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191140.1"
                     /locus_tag="IE257_RS28495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58450"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_229920711.1"
                     /sec_met_domain="TauD (E-value: 7.2e-44, bitscore: 144.0,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAEGRESLVERVRARRASLRASLLEHGALLLRGFSVPDVSAFD
                     SVVRELSGDPLTYTERSSPRSAIQGQVYTSTDYPPNEEIFLHNENSYQQAWPMALYFYC
                     VQPPLTLGATSLAGTREVLARLDPSVREEFTRRGWRVVRNFRPGIGLTWQHVFNTDDRA
                     AVEAYCADNDIEAEWLPNDALRTTAVRKAVHRHPVTGDEVWFNHAAFFHLTTLDAEIRE
                     GLLEMFDESELPTNTYFGDGGVISDEVIEHVRDCYRAATVRFDYREHDVLVIDNMLTSH
                     GREPFTGPRRIAVAMAEPFHP"
     aSDomain        complement(12295..13128)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS28495_TauD.1"
                     /evalue="2.40E-44"
                     /label="IE257_RS28495_TauD.1"
                     /locus_tag="IE257_RS28495"
                     /protein_end="294"
                     /protein_start="16"
                     /score="144.0"
                     /tool="antismash"
                     /translation="RRASLRASLLEHGALLLRGFSVPDVSAFDSVVRELSGDPLTYTER
                     SSPRSAIQGQVYTSTDYPPNEEIFLHNENSYQQAWPMALYFYCVQPPLTLGATSLAGTR
                     EVLARLDPSVREEFTRRGWRVVRNFRPGIGLTWQHVFNTDDRAAVEAYCADNDIEAEWL
                     PNDALRTTAVRKAVHRHPVTGDEVWFNHAAFFHLTTLDAEIREGLLEMFDESELPTNTY
                     FGDGGVISDEVIEHVRDCYRAATVRFDYREHDVLVIDNMLTSHGREPFTGPRRIAV"
     misc_feature    13519..13533
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.97"
                     /tool="antismash"
     gene            13551..14690
                     /locus_tag="IE257_RS28500"
                     /old_locus_tag="GCM10010343_58460"
     CDS             13551..14690
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025007.5"
                     /locus_tag="IE257_RS28500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58460"
                     /product="cupin-like domain-containing protein"
                     /protein_id="WP_189972755.1"
                     /transl_table=11
                     /translation="MGRAAVLTTTPLIIRGSGALDTMRGWTPEYVSERLGEREVPVAIA
                     DPDGAFRYNTAAREGLRHEPMRGSRLATEFRDTASGRRLSMQQMSIPNALVELRDELAV
                     PPYIPTDVITDINLWMASESSSTPLHYDNMNNLFAQLDGRKKFVLFNPSQSDLLYPGPL
                     DIRTRHLSTVDLSDPDLERFPKFAQAEYWEAVVLPGDLLFIPAFWWHQVSAPDISVSVN
                     YWWRADVRDCTCPSYFRQLYLDLVIEDVRGLFVTHDLRALGNGSAALLTLAEQTIGHGE
                     AGVAARLCGGVIVAAAKDTCTELGIAPAGGIDDAFAELEKRGAWSAEDADAARRGLALA
                     VAAGPDRSVPAPDVQKIIGRLRSSTLNWEHPARVGGDRP"
     gene            14842..15507
                     /locus_tag="IE257_RS28505"
                     /old_locus_tag="GCM10010343_58470"
     CDS             14842..15507
                     /NRPS_PKS="Domain: ACPS (89-153). E-value: 4.8e-13. Score:
                     41.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS28505_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058984.1"
                     /locus_tag="IE257_RS28505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58470"
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="WP_308433296.1"
                     /transl_table=11
                     /translation="MFGTPPPSPPLFAQEARLIEGVVERRRSDFTTVRTCARRAMGRLG
                     FPPAPILRGPRGEPLWPPGLVGSMTHCDGYRAAALARAEDLASLGVDAEVNDPLPREGM
                     LRIVTTEEERAWLAPMIERRPDVAWDRLVFSAKESVYKAWYPLTGRWLDFQEAVITVDP
                     DLGTFAARLLVPGPLVGSARLSDFPGRWTTERGFLMTAVALPAPSRPDESPTTPPPAR"
     aSDomain        15109..15300
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS28505_ACPS.1"
                     /evalue="4.80E-13"
                     /label="IE257_RS28505_ACPS.1"
                     /locus_tag="IE257_RS28505"
                     /protein_end="153"
                     /protein_start="89"
                     /score="41.1"
                     /tool="antismash"
                     /translation="GVDAEVNDPLPREGMLRIVTTEEERAWLAPMIERRPDVAWDRLVF
                     SAKESVYKAWYPLTGRWLD"
     gene            complement(15564..16784)
                     /locus_tag="IE257_RS28510"
                     /old_locus_tag="GCM10010343_58480"
     CDS             complement(15564..16784)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884401.1"
                     /locus_tag="IE257_RS28510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58480"
                     /product="TIGR02679 family protein"
                     /protein_id="WP_229920712.1"
                     /transl_table=11
                     /translation="MDEARLRRVLGGADLAWLVERARRRMERGQPLTGAVSLATPSPAE
                     RSAAERLLGRTPGTGRALTVRLDAVDAVLVRSGISPGGLEAAVTVLAGRVVPLDDVRRS
                     EEQAWGEAYAPLTLLAEEHPEYAVWAGRIRDDGLVRRLARTSAAARLLMEQTVRVLREL
                     PVEPARSLSVFAADILGSAHALDDGMPVATLALSGARALTCHPGGAGAAWRRAAWASAG
                     LLRDDVSSTVLTLNLRGTAALDWMADVGEPCVLTLRQLAHRPPRTAPPVVHICENPAVL
                     SAAADHHGPDARPLVCVQGQPSAAALTLLSRLHELGAEFRYHGDFDWGGLRIATTLSGH
                     VPWRPWRYTADDYREAVVAAGPDLRPLDGKPALSPWDPDLARALAEQAVRVEEEAVLDV
                     LLTDLAG"
     gene            complement(16796..20950)
                     /locus_tag="IE257_RS28515"
                     /old_locus_tag="GCM10010343_58490"
     CDS             complement(16796..20950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143454.1"
                     /locus_tag="IE257_RS28515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58490"
                     /product="TIGR02680 family protein"
                     /protein_id="WP_189972758.1"
                     /transl_table=11
                     /translation="MTPRPAPPAPARPRWQPLRIGLVDLFHYDVEEFHFRDGRLLLRGN
                     NGTGKSKVLALTLPFLLDGDLSARRVEPDGDAGKRMEWNLLLGGEHPHSERLGYTWVEF
                     GRRDAVSGEEQFRTLLCGLKAVSGRGIARHWWAVTGQRIDHGPADVRADGSLSLLDATG
                     TVLSRDRLIEAVAERGMVYDQAKAYRRAVDEALFGLGEQRYAALVDLLIQLRQPQLSKR
                     PNEAALSRALTEALPPMDQAVIADVAEAFRSLDEEKEELRAAGAAERAASVFLDHYRRY
                     ARTAARRRARLPRSEHSKYEQLLRDLAEAQAGKTAAEEDRAAAEERVAALTETRARLEA
                     ADAALREGPEMRSARELERSALALDRAEGDCARAIDDREKASIQHTKALGRLGAAENRL
                     RVARELSGDTLLRARETAAAARLNLPGDDGQAVADLRAAVAEATDRRHRTLTHVEALAD
                     QAEAAAAGRRAAVLRLDETETELAHAAEALETAEDTAQSAGRALVDAVREHAGRCGELA
                     YADPAGLLDELQEWTRHQDGPYPARSRASEAHSATAAVLADQAAQSAHHRAGLAARTRD
                     TEQELAGLESGGRRGPQAPYTRTPGLREQAPGAPLWRLIDFREEVTDHDRAGLEAALEA
                     SGLLDAWVRPDGAALAADGHDVLLAPNIGPVEGMSLAEVLRPAVDHGDAQAARVGVEAV
                     ARLLEAIGLGGAFGDTASADDAPGAGLSGTGATDGTWVALDGRHRVGVLTGRWAKPAAE
                     YIGEGAREAARRTRIAALQAELSLLRQESADADAQAQALATRRRTLDTELAAVPDDAPL
                     IRAHADAAAAADTMRRARTRCDERAAEVTAAAERAESAAAELHETSADLGLPPDRPALA
                     AVRKALAELGVVLAGLWPALRERSEASRQADDEREEAVRAGERTAELAVRAEEAAREAA
                     AADERLATLRSTVGAAVAELERLLAETAEALRSCAADERRSRDQHTEADRRASRAEGRI
                     EQLEKAVTEAAAARSEAIAALQRFTATGLIAVALPDLAVPAADDGPWVPTPAIALARAL
                     ESELSTTDDSDGAWERVQRRVSEEFKTLQDALSRHGNTASARMVEDGMIVDVIYQGRER
                     AVPELAEALAVEVGELTRILSAHEREILETHLITEVAGTLQELIAAAERQVLAMNAELE
                     ERPTSTGMRLRLVWRPSRKAPVGLAQARGRLLQTADAWTAEDRAAVGEFLQTQIARQQT
                     EDAAGSWLEHLTAALDYRSWHEFAVERQQHGRWVPATGPASGGERVLAVSVPLFAAASS
                     HYASAGSPYAPRLVTLDEAFAGVDDDSRAKCLGLLHAFDLDVVMTSEREWACYPQVPGI
                     AIAQLARVDDVAAVLVTRWEWDGTARTRSEDPVRAVDPEPL"
     gene            complement(20947..22194)
                     /locus_tag="IE257_RS28520"
                     /old_locus_tag="GCM10010343_58500"
     CDS             complement(20947..22194)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267067.1"
                     /locus_tag="IE257_RS28520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58500"
                     /product="TIGR02678 family protein"
                     /protein_id="WP_189972887.1"
                     /transl_table=11
                     /translation="MTTPLAEVLDGQHAAERRKAARALLKQPLLLAHGAYADEFRLVRR
                     HASELRDWFDRNTGWSLQVDAETARLGKIPGVPDDATHPAREVTRSAVPFSRRRYVLLC
                     LALAALERGEAQIALGRLADQIMLDAKDPRLAAAGIQFTLDRRDERLDLAAVVRLLLHL
                     GVLRRVAGDEDAYVSGAGDVLYDVERRVLAGLLATRRGPSTVRAETLDARLTELAAETA
                     LDSDELRFRAMRRSLTRRLLDDPVLYYDELTDAELGYLTRQRGFLTARINELTGLVAEV
                     RAEGIAMVDPEDDLTDVRMPESGTRGHVTLLLAEYLTAVGGVVVPMTDLERRVVELAAE
                     HSGFWSKSAREPGAEADLAEQAIARLAALGLVARTADRVVPRPALARYAVGETVVLEPR
                     TAGTAQVPAQRKAYRP"
     gene            complement(22194..23756)
                     /locus_tag="IE257_RS28525"
                     /old_locus_tag="GCM10010343_58510"
     CDS             complement(22194..23756)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267066.1"
                     /locus_tag="IE257_RS28525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58510"
                     /product="TIGR02677 family protein"
                     /protein_id="WP_189972888.1"
                     /transl_table=11
                     /translation="MTSPQAEGTPDGYGPFAHLTAPNVLLYRAVMRAFLVAKERFAVHL
                     RPEDVYAGLASGVRPTELDAVVKALDSLVGWGNLRADPDTGRVTAVEDFYRKRFIYQLT
                     REGEAAEEALSAYDEALGRRGALQAVALHDIVTQLRALLVLTAEEEPDPAKTHLALDGL
                     ASRFGALADNARAFMGSLQRTIDLHDVGEEVFLAYKDQLIQYLERFIQDLITLGGRIAR
                     LILELEEGGSIERLLRAAAAREAADATPQEAAYAGQAAYERWAGRWAGLASWFLSRDGR
                     ESQARLLRGRALGAIPQLLAVVRSLNERRAGRSDRSADFRTLARWFAEAPDDDARHRLW
                     RTAFGLYPARHLTVDAETLAARHARPEPAGTAWADAAPLRISPQLRRTGSYERRGKPRK
                     VEDRQEARRLLAETAAKQAAETAAARARLVTHGITTLSGLGELDPLSFRLFLQLLGDAL
                     ATWRPGMTHTAATSGDGSMEIRLTAPTDGSIAEVRTPDGTFRGPDHTIEIVDLTERTGG
                     SEA"
     misc_feature    23718..23734
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.06"
                     /tool="antismash"
     gene            complement(23860..24621)
                     /gene="drmC"
                     /locus_tag="IE257_RS28530"
                     /old_locus_tag="GCM10010343_58520"
     CDS             complement(23860..24621)
                     /codon_start=1
                     /gene="drmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036926.1"
                     /locus_tag="IE257_RS28530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_58520"
                     /product="DISARM system phospholipase D-like protein DrmC"
                     /protein_id="WP_209468409.1"
                     /transl_table=11
                     /translation="MRWARLLKAAAEAEAAAGVLALGALADGIAAGQPRATLLTVRSAS
                     TYTEAAAAVLDAMDADGLSRAEAAACLHGLAAGYAQRDREQEVSLVWSGPSSHRVPVRS
                     TDRVLLGLIAEARTELILMTYSARRYPPLTAVLQDAAARGVGLDIVVETLQGAGSALSG
                     DEPASAFTDVPGARLWHWPLDKRAELGAKAHAKLAVADRQTLLTTSANFTQSGVDRNIE
                     AGTLIRGGSAPARAAEHVSELQRTGVLQRFW"
     misc_feature    complement(24718..24733)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.98"
                     /tool="antismash"
ORIGIN
        1 ccttcagcac ggccagcagt gccacgacca gctcgacacc gcgctccagg cggacgccga
       61 ccacggaacc cgtggtgacg ccccgcgaca gcagcagccg ggccaggcgg ttcgcccggg
      121 cgtccagctc ggcgtacgag tgctccacac cctcgaacac caccgcaacc gcacccggag
      181 tacgccccac ctgcgcctcg aacaaccccg gcaacgacga gggctcgacc tccaccgccg
      241 tgtcgttcca ctccaccagg acctgccgac gctccgccgc gtccagtacc tcgaccgcgc
      301 cgagcgcgag ctcgggaccg cccgccgccg cccgctccag ggcggtcagc aggttcctgg
      361 ttgccgtgca caggagcgtg cccacctgcc gcgggtccgc cggggcggcc gcgtcgacgg
      421 tcaggcgcat cccgtcctcg tcgtcatcga ggttcaccgc gagcgggtag ttggtctgct
      481 cccggtagag ccgcagctcg acaccgtcga agagggctcc gctcttgctg acggaacggt
      541 cgttgtggcg gtagttgaac atggacgcga agaggggggc ctccccctcc accccactcg
      601 cgttctgcgc cacggccagc ggcgcgtgct cgtgctccat cagcgcggcg agctggcggc
      661 gcatggcgct caccgcgccc atcacaccca gctgtccggt cttcacccgt acgggcagca
      721 tgttcatgaa cggaccgagc acccgggcct cgtcggcgtc ggcgcccatc cggccgaaca
      781 acaccgttcc gaagaccacg tcgtcccggc cgctgaccgc ggccagtacc cgcgcccacg
      841 ccacgtgcat cagcgtcgcg gggctcgcgc ccaccttccg cgcgaccctg cggagccgtc
      901 gctccaggtc ggcggcgatc cgtacctcgg tctcccgcga cttcatcccg ggctcacgcg
      961 tgttcagcag cccgaacggc gcggtcggct cggtgacgtc acccaggagg tcggtgaaga
     1021 actgttcgtg acccccgtcg gccagtccgg cccgggtctg gaccacggcg tcgcggaagg
     1081 gcagcggctg cggcagttcc gcgccgcgtc cacccatgaa ctcgcggatc tcggagagca
     1141 gtacctcgac cgtcgtgtgg tcctgcacca agtggtgcag acgcagcagc accagccgtc
     1201 ggccgtccgt gaccgtggcc acgtggagtc cgagcagcgg ggcgcgccgg atgtccatgg
     1261 cgcggcccac gaccgccggc aactcggcca ccgggtccgc ggcgtgcggg tcgatgacca
     1321 cctcggtcac cgggagctcg gcccggcgcc ggaccacctg gagcggctgg ggcagtcctt
     1381 cccaggcgat cgccgtacgg aagatgtcgt gccggtccag cacctgctgc agcgcgtccg
     1441 cgaaggagtc cacccgttcc gcggagtcga actccaggac ggcgcaggcg acataggtgt
     1501 cctcttcacc gtcggccagc aggtggtgga agagcaggcc ctcctgcagc ggggccagcg
     1561 ggtagacgtc cgcgatgttg gccgcaccgc cctcgacggt ggcgaccacg cgcgccacct
     1621 cgtcggcgga caggtcgacg agcggcagca tctccggggt gatcgccgtc gcgtcggcgg
     1681 ggatcaggtt cgcgggtacc tcgatggcgc tcgcgcccac ggaggcggcg aggccggccg
     1741 gggtgggcga gtcgaagaag gcacgcaccg acaccgatac gccgagcttg cggatcgctc
     1801 cgaccaggcg gatcgccatc agggactggc cgccgagctg gaagaagttg tcgtcgacgc
     1861 cgacccgctc cagtcccagg acgtcggcga acgccgcaca gaggatctcc tcgcgcgcgt
     1921 tcgagggccc ccgcccggtc ccggcgcggg tgccgaagtc cggggcgggc agcgccttgc
     1981 ggtccagctt gccgctcatg gcgagcggca gtgcgtccag taccacgacg gcggagggga
     2041 ccatgtgctc gggcagctgc tccgtcgcga aggcgaggac ctgttcggtc aggtcctcga
     2101 cgtcttcgtc cgtcaccacg tacgcgacca gctggacgtc gccgggggtg tcctcgcggg
     2161 cgatcaccgc ggcctgcgcc acctgcgggt gggccgcgat cacggcctgg acctcgcccg
     2221 gctcgatgcg gtagccgcgt accttgacct gctcgtcggc ccggccgagg tactccagtt
     2281 cgccgtcggt gcgccgccgc gcgacgtcgc ccgtgcggta catgcgcgca ccggcctcga
     2341 aggggttggc gacgaaccgc tcggccgtca ggccggcgcg gtccacatag ccgcgggcca
     2401 gctgcacgcc cgcgatgtac agctctccgg cgacgccggg ggcgaccggg cacaggaagg
     2461 aatcgaggac gtacaggcgc atgttggcga tcggacggcc gatcggcacg ggctcgccca
     2521 cgacctgtcc ggcccggatc tcgaacacgc agcagcccac gaccgcctcg gtcgggccgt
     2581 actcgttcac gatcaccgag ccgggcgcgt gctccagcca ggactgcacc acggagcccg
     2641 gcagggcttc gccgccgacc acccaggtgg atgcggccgc ctcgatctgg ctctcggtca
     2701 gcatctcggt gagcaggggg aggtgggccg gaacgacctt cgccagtccg tagccgccgt
     2761 ggccgcggag cagttccgcc aggccctcgg cgctgccttc gcggctcacc accaccgggg
     2821 cgccggagat cagaggtatg acgatgctgg tcacggtcag gtcgaaggcc agcgaggagt
     2881 gcagcggcgc ggcgcccgcg ccgtaggcgc cggcggccca ctgagcgtag ttggccaggc
     2941 cgcggtgggt gaccgcgacc cccttcggcc ggcccgtcga gccggaggtg tagatcacgt
     3001 acgccagtcc gtccgcggcc gccggcgccg cggggacggt cgcgggctcc gccgtcacgg
     3061 tcccggacgc caacgcgtcg gccagggtca cgacatgggc cgtaccggtg agacgtgcgg
     3121 cccgcgcggc gctgtcggtc agcgtcacga cggcgccgct gtccgccagc aggtaggcga
     3181 tgcggtccac cgggtggtcc gggtcgatgg gcaggtaacc ggcgccggcc ttccaggccg
     3241 cgaggatcgc gacgacagcg tccgcgctcc ggggcaggca cacgcccacc acggactcca
     3301 ccgtgacgcc ctggcccacc aggtaccgcg cgagtgcgtt cgcacgctcg tccagttcgg
     3361 cgtacgacac ctcgacgccg tccgcgatca ccgcggccgc gtccggggtc cgggcggcct
     3421 gcgccgcgaa gagttccggt acggagtgac ccgcgaactg cgtcgcggtg tcgttccact
     3481 ccaccagcac ctgacgacgc tcgtcggcgt ccagcaggcc ggaacggccg accggttcag
     3541 cgggatcgac cgagacgagc cagtgcgcga gcgccaggaa gcggcggcag acctcgtcgc
     3601 cgggcgacag atcgggcgca tcggggttga cgtccacggc gatcttgagg ccggacctgt
     3661 cgtacacgtc gatgcgcgtg ctgtcgacag ggccactgga caggttgtgc gcggtgacgg
     3721 tgcagtcccc gaagggcagg gcgtagatgt cgaaggacat cacgttgatg agcaggtccc
     3781 agagaccgcc ctcgccgagc atcgcgtcgt tgagcatgtg ctcgtagcgg tagcgctggt
     3841 ggcgcaggcc cttcatcacc gcacgggtgg tctgccgtac gaggtcggcg accgaggtgt
     3901 ccggggagat cttcacccgg atcgggagga cgttgttggt catgaagggg atcgcgaggt
     3961 cgcgtgtgcc cgagcggccg ctcaccggta cgccgacgac cacgtcccgc tgtccggtca
     4021 ggtggtgctg gtacagggca gcggcgctga tcatcaggcc ggcgaagttg gtcccgagcc
     4081 cacgggcggc cgccttcagg tcggcgccga cggtgtcgtc gacgctctcc acgaagcgga
     4141 ccggtgcgcg ctgcgcgcgg cccgcgtagt tgctgccggg gccctctgcc tcggggagac
     4201 ccgcgaggac accgcgccag tagtcccggt cggtcgcgtg ggcgtcggag gcgcggtact
     4261 cgcgttcggc gtccatcagc acggtgctgg aggggagggc gccctcttcg accgagccgc
     4321 cctggagcag ggtgttgtag acctgcgaca gcctgccgac caccaggccc gcgctgcggc
     4381 cgtccaggat gacgtggtag gcgcgctggt accagaaggt gagccggggg ccggccgtgt
     4441 agatcttgat ggtgtacagg gagcggtcgg ccgctccccg ctcgctgcgc aggtcctccc
     4501 acatcagccc ctcggccgcc gcctgcggat cggcctcggc gctgatgtcg atgacctcga
     4561 cggggtagtc ctccacgtcg tggaagtact gccgcggctg tccgtcgact tcacggatgc
     4621 gcaggcgggc ggcgtccgcc tcttccatca gccgctgcga ggccttcacc aggaggccca
     4681 ggtccacgtc tccgtcgagc gccaggtact cggcaccgtt gaagcacggg ttctcgggcg
     4741 ccagctgatg gctgtaccag atcgcgagct ggcccgccat catttcccgg agcccacctt
     4801 cagacatagc cattcccgcg cactccaatt cggatcgaca catcggctgg aacaacaacg
     4861 ggccgccaca ttcggacatg ccgctcgaat gaccagctca ccttgcacac cgctgcaact
     4921 tgctattacg gacgcggcca caaggcaggc ccggaccgga tccgaatagt cgtcgctccg
     4981 gtggaatcac ggcaatggtt accgctgtga cctgcgccca tggcgtggtg cgcgcttcgt
     5041 cggcacgcac gctcctctgc tcaataccgg atcactatgg ctcagggccg ctgccccgat
     5101 caatgcgcgc cggcagcccg gacaccgtgc tccgtgcctg ctcagtcagg gtgtgcacga
     5161 gtcgttcaac tgcgccgcag cggcggttga acacgccggg ggtgagcggc accaccctgc
     5221 tgtgcggtgc gcgcggcggt gctcctcacg ccggtgcgct cccgaggacc cgaccgtggg
     5281 cggcattccg ccgatgcccc ggccgcgtgc atgatatttc cggtcttgaa ttccaacgaa
     5341 cccgtgaggc attcgcatgc acaatgagtc ggccgacccg gcccctcaga tcaatctggt
     5401 ggaccccgga ctctactcgc acggcgatcc gtttgtgcag tggcgctggc tccgcgccaa
     5461 tgatccggtg tattggcatc cgccgacgga gcttcccggc ttctgggccc tgaccaggta
     5521 cgaggacgtc cgcaccgcct atcgcgacgc ggagacgttc agctccgccc agggcattct
     5581 gctccgaccg gccgatcacg gcgcggatcc cggtggcggc cgcaccctcg cgctgaccga
     5641 cgctccgcgc catcggcagc tgcgcggact ggtggacgag tggttcgccg tccgctcggt
     5701 ccgggcgctc gagcacgaga tgacggacat cacgaggagg atcgtcgaca aggcgctgga
     5761 gcagggcagt tgtgacttcg tcacggacgt cgcggcccgg gtcccgctct atgtgatctg
     5821 caagatgatg ggggtaccgg agtccgactg ggagcacctc tacgacctga cctcccaggc
     5881 cttcgcggcc ggcgacccgc tcgaacgcag gttcgcgcac ctgaacatcc tcggctactt
     5941 cgaggaactc caggcggaga aggcggcgcg gccgggcgac gacctggtca gcgtcctggc
     6001 gacgggcacc gtcgacggtg aacgcctcag ccccgacgac gtgatcctga actgtgacaa
     6061 cctgctggtc ggcggcaccg agaacacccg gatcgccgcc gccggaggca tgctcgcctt
     6121 cctcgaacac ccggaccagt ggcagctgtt ggtcgacgag ccgaccctgc ttccgtcggc
     6181 cgtggaggag gtcatgcgct ggacctccac cgccacgcac atcctgcgga ccgccacgcg
     6241 gaagaccgag atccacggca ggaccatcga ggcgggtgac cgggtcgtct tctggctgcc
     6301 ctcggccaac cgcgacgaga ccgtcttcga ctccccggac tcgttcgtca tcgcccgcaa
     6361 gccgaaccgg cacctggctc tcggcttcgg tgagcacttc tgcctcggga gcatgctggc
     6421 ccgggtcgaa ctgcggctgc tctacggaga gttgcttgac cgaaacgtac gggtcgagct
     6481 ggacggcgct cccacgctgc tggactcgat cgtcgtcaac ggcccggcga agctccccgt
     6541 caagctgacc ctttcctgac ctacggaccg aaacgggttc cggccccgcc actgatgcgg
     6601 cggggccgga acccgttgtc ctctacccgc gctctagcga gcggcgagca gcggagccag
     6661 agcctccgag atcgggccga tggcggggtg gtcccacagc agggtgggct cgacctcgat
     6721 gccgtagcgg tcctcgatgt cggcgcacag gctgagcacg tacaccgagt cgaggccgta
     6781 ctcggacagg ggcaggttct cgtcgatgtc ctcggccgga agccggacat aggtggccac
     6841 gcactcgcgc agccaggcgc ggacctctgt cgcatcggcc gtggccgggg cgtcggtgat
     6901 gtcggacatg gcaacctccg tggatgcggg ttctgggggg ggtgtgggac gggtgggctc
     6961 aggcgcccgt ggggcggcga gcgtgatcga aggtgagacc ggcgtcgtga cgccggagga
     7021 gttccgcgta gaggaactcg ctcagtggtt cgggaagcgg gtcatggtgg cgtccggtat
     7081 ggacgcccaa tcggtgcagg gccgcgagca cccacgcggg ctcggcgccc gggccctgcc
     7141 cgtcgcccgg ccgctcccac cacaggccca ggcaggccgc ggcggcgagg accccggccc
     7201 agcgggtcgt caggtcgaag gcgtggggcg gtgcggcggg acccagctgg tccggggtca
     7261 ggcgggccgc ctcggcggac agcgcccgta tctcggtggc gtactgcgat gcgcgcgcgg
     7321 cgagctccgc gtcctcgccc cgtccggtag gtcgctcggc gccctggagc agcgagcggg
     7381 agagcgggtc gcggccgccg gcggtgacct tgagggcgcc gaagtccagc ggcggcagcg
     7441 gttccccggg ccggaaggtg gtcgggggca gggccgggcc gtcctccgcg ctccaggtgc
     7501 ggcgcacggt caggggcagc tgcggcaaca gggcggcctg acaggagacg cgggaggcgt
     7561 ggccgaaggc ggagggcagt acgtcgcgct gcagcttctg aaagagcggc tgctcggcgg
     7621 cgcgcaggta gaactgcgag ccgagcagct cggacagccg gctcacggcg cccatcacca
     7681 gggccgggac caggagcttg accgccgacg cgtacaccgt gctctgcccg ggggcggtgt
     7741 gggccgcgcg ggcggccacg gtgacgaacg cgtccgccag gagcaggtcg gcgaacgcct
     7801 cggcgagcac ggtccgcgac agcgagaggt cggcggcggt gcctgcgtac agcctgcgtc
     7861 ccagggctcc gcgcagggcg gtgcgcagcg cggtgtcgag caggccgagg gtcatgccgg
     7921 gcagcgcgat ccgcgtcagc tggaaggacc gctgagcggt ctccagcccg tgtccgggcg
     7981 tgccgaccac ggcgtcggcc gggacggggc agtcggtgaa ctcgatcccg ccgagcggta
     8041 cgccgcgcat gccgaccgtg gcgaagcggg gcagccgggt cagcgtgtcc gatgccagcc
     8101 gggccgtctc cagcaggagc tgggagtggc tgcggctgcc ggccgcggcg tcggtccggg
     8161 cgaagagcac cacggctccg gcccgggcga ggttggccac cacttccttg cggccgttga
     8221 cgagcagttg cccgtccggg ccgggcaggg cggtcagctc ggcccgcgcg aagtcgttgc
     8281 cgtgggccag ttcgtggtag ccgcaggcga cccggccgcc ggagagcagg tgaccggcga
     8341 gccaggactg ctgctcggcg ctgcccgagg tccagacgtt gacggcggcc atgaaggaac
     8401 ccgcgccgta gccgagtccc agggcgggat cgcgccggta gacggcgcgc atcacgccga
     8461 tgagttcctc ggggccggcg aaccggccgc ccagggcttc ggggacgaag tgggcgttca
     8521 gtccgaaggc gtccagcagg tcctctccgg ccgccagcat ggacccgtcg gcgtcggcgg
     8581 ccagcacggc ctcgcggccg accgggttgc cggcggcacc cgcgtcaccg aagagcgcct
     8641 ccagccggtc gatcgggtcc ggggatgccg cgggggacgt ggccccagca gggtcgacga
     8701 gcgtcatcgg accggttcct ccacgggttg cacgaggggc gtgacgaggg gttcgaaggc
     8761 gtcggacggg gcctggtggc cgggtacgag cagctccagg caccgttcca gggccgcggt
     8821 caggaccacg gcgcggtccg ccgcgcacgg tacggcgagc aggtgcaggg cggcggctcc
     8881 cgcgaagcag gcctcgaact gccgggccac cgcgaaggcg gcggcggggg cgttcctgcc
     8941 ggtcggcggg agttccgcca tggcgtcggc gagcgccccg gtccgctcgg cgagcagggc
     9001 ggccagctcg gccgcgcgcg ggggcagctc ccccgccgcc gccagcgcgg tgatccgctc
     9061 ggcggtgtcc ggcacggcct ggacgatgct gcagcccgtg cggctcacca ggcgcagggc
     9121 cgccggatcc agctccggca gcggggcgcc gccggtgacc gcggcgagcc cggtcgcgtc
     9181 gtaggaaccc ttgcggatga gcctggccag gagcgggaac tgggagatga gcagtgagcg
     9241 gttcaccgcc gtgctgccgt cgaagacggc gacgatccgg tggtcgcgct ccagcttctg
     9301 gaacatgccg tcggcgtgtt gttccgtcaa aaatccacga gctccgagga gttcggccag
     9361 gtcatcgatg gcctgctgga cgatccaggg tacgcccgcc ttgacggtcg ccgagacggc
     9421 gctcatctct ccgggcagtc cgtgcgcact gcgcccgccc agcagggccg cggcatcggc
     9481 cagggccagg gacgcggcgg cgcggcccag tacccgccgg gccagcggca gcagggccag
     9541 ccgggtgccg tggagggcgc gctcgacggc gaagtcggcg accagccgga gcgcgtgctc
     9601 acccgcgccc agggagagcg cggcgcagag cgtacgggtc agctgcagcg cccgcaggac
     9661 gatccccagc ccgtcgccga ccccgccgac gagtgcgtcg gccggtaccg gtgcgtcgcg
     9721 caggcgcagc ccgctgatgt ccgcgccgcg gatgccgtgc gtcggctcct tgggcagcgg
     9781 ctcccacgcc ccttccggga gggcggactt gtcgatcagg aacaggctga agccgcgtgg
     9841 gcctccggcc ggatcggtgc gggccaggac gcagatgagc cggccccggg tggcgttgtt
     9901 gatcggccac ttctctccgg tgatccgcca cgttccgtcc ggctcggggg tggcggtcag
     9961 gttcccggcc agcaggtcgc tgcccatgcc ccgttcggtc aggccccagg cgaccaccgc
    10021 gttctcatcg gtcaccagcc gggccagggc ccgctgctgg tcttccgtcc cggcgaccca
    10081 cgtcgagacg gatccgagga aggtcttgcc gtgcgcgacg gccaccgtca cgtcacgccg
    10141 cgccacctcg cgcagcgcgc tcagcagctc gggcagaccg cccgcgacgc cgccgagccg
    10201 ctcgggtacg taggcgcggg ccaggccgga ggcgtccagc aggtcgcact cctcgccagg
    10261 aaaggcctcc gcggcgtcca gggcggcgct gcgggccgtg ctgaacgcac cgcccgccgc
    10321 cgccccggcc gccatggcgt cggccagggc cgcggcgagg ccggtgggcc actcgggtac
    10381 gtccgcgctc acgcggtcgc tcccgccagg gccgcccgga caccgggcgc catctcctcg
    10441 tacagcgggg tgaggtctcc cgcgaggaac aggccgcgca tctctgcgcg ctgcaccttg
    10501 ccgctcgtgg tcttgcggac cgtaccgggc cgcatcagca cgatgcccgc ggtggacacg
    10561 ccgaactcgc ggtggacggt ggcccgcatg ccgatggcca gttcgcgcag ctcctcctgg
    10621 gtgaagcggc cgcgcacctc gtgcacgacc accacttcct cctgtggcgc ggggacggtg
    10681 aacgccgtac cggccagggt ggccaacggg gcgtgcgaca gccgcagttc gtgctcgatg
    10741 tcgtgcgggt agaggttgcg gccgttgacg atgagcaggt ccttggtgcg gccggtgacg
    10801 tagatctccc cgtcgaggaa cacaccgagg tcaccggtgc gcatgtaggg cccgtcgccg
    10861 tcggcggtcc gggcgtggaa gatctgttcg gtgacgtcgg ggcggttcca gtagccggcc
    10921 gcgacgctcg gaccgcgcag ccagatctcg cccgtcgtgc cgtcggtcag cgcccggccg
    10981 ctctccgcgt cgacgatgcg gacgtcgagg tcggggacgt cgccgcagcc gacgagttcg
    11041 cgcaccgggc caccgggctg cgggtcctgg acgacgtgct tctccagcgc ctgcgggtcc
    11101 accgcccgga tgcgcggcgg ccgggtcgag cggccggaga tgaacaccgt cgcctcggcc
    11161 atgccgtagc acggcgcgag ctgctcggcc cggaacccgg ccgctccgaa gcgctccgcg
    11221 aactgccgca gggtgctggc ctggatgggc tcggagccgt tcgcggcgaa ctgccagcgc
    11281 gacaggtcga gcgtggcgat ctgcgcgtcc gtgacccgcc gcaggcacag ctcgtaggcg
    11341 aagttgggtg ccgcggagaa gccgatgtcg taccggtcga tcagcgcgag ccagtggtgc
    11401 ggacgcttca ggaacgccat cggcgacatc aacgcgacgc tgctgcccag gaagaggccc
    11461 ggcagcagct gccccatcag ccccatgtcg tggtaaagag ggatccagcc gccgaagttg
    11521 gtgtcctcgg tgaagccgag ggaacggctc aggctgtccg cgttgtggag caggttgcca
    11581 tgggtgacca tgacgccctt ggggtctccg gtcgatccgg aggtgtattg cagcagcacc
    11641 acgtcctggg tcgtggcccc ggggtcgcgc cagcgcgcgg cgtcaccgaa gccggggccg
    11701 tcactggcgg cgacgggcag ttcgagtccg gtgtcggata tccactgctg cgcctcggcc
    11761 agctggccgg tgtcggtgag cgccacgctg acaccggcgt ctcgggcgat catcgtgacg
    11821 cgccgctgct ggtactggaa ctgaccgggc atcggggagg gcaccgcgat gacccccgcg
    11881 tagaggcacg cgaggaacgc ggtgacgaac ggcagtccgg ccgggtgcag cagcagcacc
    11941 ctgtctccgg gggcgcagcg ctcctggagc caggacgcga cgcggcgcgc ctccgcgtcg
    12001 agttccgcgt aggtcaggct gcgcgagccg tcggccgcgt cgaagtcgtg gacgaacgtg
    12061 acggcggtcc ggtcggcgcg gtcgacggcg tgccgccgca gcaggtggag cacgctgggt
    12121 tcgcgggtca tgctcacagg gttctcctct ccgcgcggtc gggcgagcgc ggcctgaaat
    12181 gtggtggtct cgacggtgac cggaaatcgg gagggctgcc cccgtgagtt cccgagtgaa
    12241 ttcccgggcg cattcccgga gacggaacta cgggtggaag ggctcggcca tcgcgacggc
    12301 aatccggcgc gggccggtga agggttcccg gccgtgcgag gtcagcatgt tgtcgatgac
    12361 caggacatcg tgttcccggt agtcgaaacg cacggtcgcg gcgcgatagc agtcacgtac
    12421 gtgctcgatg acctcgtcgg atatgacgcc accgtccccg aaataggtgt tcgtcggaag
    12481 ttccgactcg tcgaacatct cgagaagtcc ttctcggatc tcggcgtcca gggtggtgag
    12541 gtggaagaag gctgcgtgat tgaaccacac ctcatcgccc gtgacggggt gacggtggac
    12601 cgccttcctg accgccgtcg tgcggagggc gtcgttcggc agccattccg cttcgatgtc
    12661 gttgtccgcg cagtacgcct ccactgccgc acggtcgtcg gtgttgaaga cgtgctgcca
    12721 ggtcagtccg atgccggggc ggaagttgcg caccacgcgc cagccccgtc gggtgaactc
    12781 ctcgcggacc gaggggtcca gccgggcgag cacctcgcgg gtgccggcga gggaggtcgc
    12841 cccgagcgtc aacggcggct gcacgcagta gaagtacagg gccatgggcc aggcctgctg
    12901 ataggagttc tcgttgtgca ggaagatctc ttcgttcggc gggtagtccg tggaggtgta
    12961 cacctgcccc tggatcgcgc tgcgcggcga ggaacgttcc gtgtaggtga gcgggtcgcc
    13021 cgacagctcg cggacgacgg agtcgaaggc gctcacgtcg ggcacggaga agccgcgcag
    13081 gagcagggcc ccgtgctcta gcagggaggc ccgcaggctc gcgcgccgtg cccgtaccct
    13141 ctcgacgagg ctctctctcc cctccgcttc gatcacgagt gggaatgctg tgctgtggct
    13201 catgagttgg gtgttccctt ccgaagcgat acgcgagccg cgtgaattcc tcttcgctcg
    13261 ggagcaattc atggcctgtc gcggcgtgat cgggcagccc agggctcggc cccgacggag
    13321 tgtgccgcaa ccggtgcacg ggccgccacc ctcattggac cgatcaactg cggcacgtgc
    13381 accggttgga cgcggatgaa cagcgcgcgc ttgaacggcc gttgtgcgat ccatcgccga
    13441 tccgtagcat gcgatcttcg tcgcgtattc tgtcggaatg gggatctgtc atgcagggag
    13501 cccgatcact ggggcatgtg gaagtcgttt cttcattccc tgaagaaccc atgggacgcg
    13561 ccgcggttct caccacgaca ccgctgataa tccgcggcag cggggctctc gacacgatgc
    13621 ggggatggac tcccgagtac gtctccgagc gcctgggtga gcgcgaggta ccggtcgcca
    13681 tcgcggaccc ggacggtgcg ttcagataca acacggccgc tcgcgagggc ctgcgccacg
    13741 agccgatgcg cggctcgcgg ctcgccaccg agttccggga cacggcgagc ggccgaaggc
    13801 tcagcatgca gcagatgtcg atcccgaacg cgctcgtcga actgcgcgac gaactcgccg
    13861 ttccccccta catcccgacc gatgtcatca cggacatcaa cctgtggatg gcctcggagt
    13921 cgtcgagcac gcccttgcac tacgacaaca tgaacaacct gttcgcccag ctcgacggac
    13981 gcaagaagtt cgtgctcttc aatccctccc agagcgacct gctctacccc ggccccctgg
    14041 acatccgcac ccggcacctg agcaccgtgg acctgagcga ccccgacctg gagaggttcc
    14101 ccaagttcgc gcaggcggag tactgggagg ccgtcgtcct gccgggtgac ctgctcttca
    14161 tcccggcctt ctggtggcac caggtctccg caccggacat ctcggtctcg gtcaactact
    14221 ggtggcgcgc ggatgtacgg gactgcacct gcccgtccta cttccggcag ctgtatctgg
    14281 acctcgtcat cgaggacgtc cgcggcctgt tcgtgaccca tgacctgcgg gcactcggca
    14341 acggctccgc cgccctgctc acgctcgcgg agcagaccat cgggcacggc gaggccggtg
    14401 tcgcggcccg gctctgcggc ggtgtcatcg tcgccgccgc gaaggacacc tgtacggagc
    14461 tgggcatcgc acccgccggg ggcatcgacg acgcgttcgc ggaactcgag aagcgtggtg
    14521 cctggtccgc ggaggacgcc gatgcggccc gccggggact ggcactcgcc gtggccgcgg
    14581 gcccggaccg gagcgtcccg gctccggacg tccagaagat catcggccgt ctccgctcct
    14641 ccaccctgaa ctgggagcat cccgcgcggg tcggtggtga ccggccttga tcgggcggac
    14701 caggtggagc tgcttccggc tgatgaggct ggcatggtcg ctggtgtcgt ccctctcggg
    14761 accaccgcgg ccgggagtca ctgctgacgg caggcgactg tgatcaccga cgtgttaccc
    14821 gctggggtgg aggcggcgga agtgttcggc acgcccccgc cctccccacc cctgttcgca
    14881 caggaagcac ggctgataga aggggtggtg gaacgtcggc gcagtgactt caccacggta
    14941 cggacgtgcg cgcgccgggc catgggcagg ctcggcttcc ctccggcgcc gatcctgcgc
    15001 ggaccgcgcg gggagccgct gtggcccccc ggcctcgtcg gcagcatgac gcactgcgac
    15061 ggctaccgtg ctgccgcact ggcccgcgcc gaggacctgg cgtccctcgg cgtcgacgcc
    15121 gaggtcaacg acccgctgcc ccgggaggga atgctgcgga tcgtgaccac cgaggaggaa
    15181 cgcgcctggc tggccccgat gatcgagcga cggcccgatg tcgcctggga ccggctggtg
    15241 ttcagcgcca aggagagcgt ctacaaggcc tggtacccgc tcaccggacg ctggctcgac
    15301 ttccaggagg cggtcatcac ggtcgacccg gacctcggca ccttcgccgc acgcctgctc
    15361 gtcccgggcc ccctggtcgg atccgcccgg ctgtccgatt tccccggccg ctggacgacg
    15421 gagcgcggct tcctgatgac ggcggtcgca ctccccgcac cctcccggcc cgacgaatca
    15481 cccaccacgc cgccgccggc ccgctgaacc agcagccccc gcccggccgc tcgggcgtcg
    15541 gccctgaccg gctccaggat gcttcacccc gcaaggtctg tcagcagcac atccagaact
    15601 gcctcctcct cgacacgcac ggcctgctcg gccagagcgc gtgccaggtc cgggtcccac
    15661 ggcgacagcg ccggtttccc gtccaacggc cgcaggtcag gtccagcagc tactaccgcc
    15721 tcgcggtagt cgtcggccgt gtagcgccag ggccgccagg gcacgtgccc cgacagcgtc
    15781 gtggcgatgc gcagaccgcc ccagtcgaag tctccgtggt agcgaaactc ggcaccgagc
    15841 tcgtgcagac gggagaggag ggtcagggcg gcggccgacg gctggccctg gacacagacc
    15901 agcggtcggg catccggtcc gtggtggtcc gccgcggccg agaggaccgc gggattctca
    15961 cagatgtgga ccacgggcgg tgccgtccgc ggcggacggt gggcgagctg tcggagggtg
    16021 agtacgcacg gctcacccac gtcggccatc cagtccaggg ccgcagtccc gcgcaggttg
    16081 agggtgagca ccgtcgagga gacgtcgtcc cggagcaggc cggcggaagc ccacgcggcc
    16141 cgccgccagg ccgctcccgc tcccccggga tggcaggtca gagcgcgggc accggagagg
    16201 gccagggtgg ccaccggcat gccgtcgtcg agtgcgtggg cactccccag aatgtccgcg
    16261 gcgaacaccg acagcgaccg cgctggttcg acaggcagct cccgcagtac gcggacggtc
    16321 tgttccatca gcagacgggc ggcggcggaa gtacgggcga ggcggcgcac gaggccgtca
    16381 tcacgaatgc gaccggccca aacggcgtac tccggatgct cttcggccag cagcgtgaga
    16441 ggcgcgtacg cctcccccca ggcctgttcc tcgctccggc ggacgtcgtc gagagggacg
    16501 acccgcccgg cgagtaccgt cacggcagcc tccaggcctc ccgggctgat gcccgatctg
    16561 accagcacgg cgtccacggc gtcgagccgg accgtcagag ccctgccggt gcccggtgtc
    16621 cggcccagca atctctcggc cgctgaccgc tcggccgggc tcggcgttgc cagcgagacc
    16681 gccccggtga gtggctgtcc gcgctccatc cgccggcgtg cccgctccac cagccaggcc
    16741 aggtcggcgc cgccgaggac ccggcgcagg cgtgcttcgt ccaccggcgg accgctcaca
    16801 ggggctccgg gtcgaccgca cgcacggggt cctcgctgcg cgtgcgggcc gtgccgtccc
    16861 actcccagcg ggtgaccagg acggcggcca cgtcgtcgac gcgggcgagc tgggcgatgg
    16921 cgatgcccgg cacctgcgga tagcaggccc actcccgctc gctggtcatg accacatcca
    16981 ggtcgaaggc gtgcaggagc cccaggcact tggcacgcga gtcgtcgtcc acacccgcga
    17041 acgcctcgtc cagggtcacc aggcgtggcg cgtacggact gcccgcgctc gcatagtgcg
    17101 aggaggcggc ggcgaacaag ggaacggaca cggccaggac gcgttcgcct ccggaggcgg
    17161 gtcccgtggc gggcacccac cggccgtgct gctggcgctc aacggcgaac tcgtgccagg
    17221 agcggtagtc gagggcggcg gtgaggtgct ccagccagct gcccgccgca tcctcggtct
    17281 gctggcgggc gatctgcgtc tgcaggaact caccgactgc ggcccggtcc tcggccgtcc
    17341 aggcatccgc ggtctggagc aggcggccac gggcctgggc aaggccgacc ggggccttgc
    17401 gggagggccg ccacaccagg cgcagcctca taccggtgga agtgggccgt tcctccagct
    17461 cggcgttcat ggccagcacc tgccgctcgg cggctgcgat cagctcctgg agggtgccgg
    17521 ccacctcggt gatgaggtgg gtttccagga tctcacgctc gtgtgcggag aggatgcggg
    17581 tgagttcgcc gacctcgacc gccagcgcct cggcgagttc gggtacggct cgctcacggc
    17641 cttggtaaat gacgtcgacg atcatcccgt cctcgaccat gcgggccgag gcggtgttgc
    17701 cgtgccgcga cagtgcgtcc tggagggttt tgaactcctc gctcacacgc cgctgtacac
    17761 gttcccaggc accgtccgag tcgtccgtcg tcgacagctc cgattcgagg gcacgggcca
    17821 gggcgatggc cggggtgggc acccacgggc cgtcgtccgc ggccggtacg gcgagatcgg
    17881 gaagtgcgac ggcgatcagc cctgtggcag tgaagcgctg gagcgcggcg atggcctcgg
    17941 agcgcgccgc ggcggcttcg gtgacggcct tctccagctg ttcgatgcgg ccttcggccc
    18001 ggctggcccg ccggtccgcc tccgtgtgct ggtcccggga gcgccgctcg tcggcggcgc
    18061 agctgcggag ggcttctgcg gtctccgcga gcagccgctc cagctctgcc acggcggcgc
    18121 cgacggtcga acgcagcgtg gccagccgct cgtccgcggc cgcagcctca cgggcggcct
    18181 cctccgcgcg aacagcgagt tcggcagtcc gctccccggc ccgaaccgcc tcttcacgtt
    18241 cgtcgtccgc ctgccgggac gcctcgctcc gctcacggag tgcgggccag agtccggcca
    18301 ggacgacgcc gagctcggcg agggccttcc gtacggcggc cagtgccggc cggtccgggg
    18361 gcagccccag atcggctgag gtctcgtgca gttcggcggc ggccgactct gcccgctcgg
    18421 ctgcggccgt cacctcggcg gcccgctcgt cgcaccgggt ccgcgcccgg cgcatggtgt
    18481 cggcggcagc cgcggcgtcg gcgtgtgccc ggatcagggg cgcgtcgtcg ggcacggcgg
    18541 ccagctcggt gtcgagcgta cgacgacggg tcgccagagc ctgcgcctgc gcatcggcgt
    18601 cggccgactc ctgccggagg agggagagtt cagcctgcag tgctgcgatt cgggtccgcc
    18661 tcgcggcttc ccgggcgccc tctccgatgt actcggcggc gggtttggcc caacggccgg
    18721 tgaggacccc gacgcggtgg cgtccgtcca gcgcgaccca ggtgccgtcc gtggctccgg
    18781 tccccgacag gccggctccc ggtgcatcgt cggccgatgc cgtgtccccg aaagccccgc
    18841 cgaggccgat cgcctccagc agccgggcca ccgcctccac tccgacccgt gcggcctgcg
    18901 cgtctccgtg gtccacggcc ggacgcagta cctcggcgag cgacatcccc tcgaccggtc
    18961 cgatgttcgg tgcgaggagt acgtcgtgac cgtctgcggc gagggccgct ccgtcggggc
    19021 gcacccacgc gtccagcagc ccggacgcct ccagggccgc ctccagcccg gcgcggtcgt
    19081 ggtccgtgac ctcttcccgg aagtcgatca gccgccacag cggggcaccg ggcgcctgct
    19141 ctcgcaggcc gggggtccgc gtgtacgggg cctgcggccc gcgccgaccg ccggactcca
    19201 gcccggcgag ttcctgttcg gtatcgcggg tccgggcggc cagtccggcc cggtggtgcg
    19261 ctgattgcgc cgcctggtcg gcgagtaccg ctgcggtggc actgtgtgct tccgaggcac
    19321 ggctgcgcgc cgggtagggg ccgtcctggt gccgggtcca ctcctggagc tcgtccagaa
    19381 gtcctgcggg gtcggcgtac gcgagctccc cgcaccggcc cgcgtgctcg cgtacggcat
    19441 cgaccagagc ccgtccggcg gactgcgccg tgtcctcggc cgtctccagc gcctcggcgg
    19501 cgtgcgccag ctcggtctcc gtctcgtcga gccggagtac ggcggcccgg cgcccggccg
    19561 ccgccgcctc ggcctggtcg gcgagcgctt ccacatgcgt gagggtgcgg tgcctgcggt
    19621 cggtcgcttc ggccaccgcg gcccgcaagt cggcaaccgc ctgtccgtcg tctccgggaa
    19681 ggttcagccg ggctgccgca gccgtctccc gggcccggag cagcgtgtcc ccggacagct
    19741 cccgggcgac cctgagccgg ttctccgcgg caccgaggcg gccgagcgcc ttggtgtgct
    19801 gaatcgaggc cttctcccgg tcgtcgatcg cgcgggcaca gtcgccctcc gcccggtcca
    19861 acgccagcgc ggatcgctcc agttcacggg cactgcgcat ctccggaccc tcgcgcaggg
    19921 cggcgtcggc cgcctccagc ctcgcccggg tctcggtgag ggcagcgacg cgctcctccg
    19981 cggccgcccg atcctcctcc gccgcggtct tcccggcctg cgcctcggcg aggtcgcgca
    20041 gcagctgctc gtacttcgag tgttcgctgc gcgggaggcg ggcgcggcgg cgggcggccg
    20101 tgcgggcgta gcgccggtag tggtcgagga acacggacgc cgcccgttcg gcggccccgg
    20161 ctgcccgcag ctcctccttc tcctcgtcca gggagcggaa ggcctcggcc acatccgcga
    20221 tgacggcctg gtccatcggc ggaagggcct cggtgagggc gcgggagagg gcggcctcgt
    20281 tgggacgttt ggacagctgg ggctggcgca gctggatgag caggtccacg agggctgcgt
    20341 agcgctgctc cccgagaccg aacagcgcct cgtcgacggc ccggcggtag gccttggcct
    20401 ggtcgtagac cattccccgt tcggcgaccg cctcgatgag ccggtcccgg gacaggacgg
    20461 tgccggtggc gtcgagcagg ctcagtgacc cgtccgcgcg tacgtcggcc gggccgtggt
    20521 cgatccgctg cccggtcacc gcccaccagt gccgggcgat gccgcgccca ctgacggcct
    20581 tgagtccgca caggagcgta cggaactgct cctctccgct caccgcgtcg cggcggccga
    20641 actccaccca ggtgtagccg aggcgttcgg agtgcgggtg ctcgccgccg agcaggaggt
    20701 tccattccat ccgcttgccg gcgtccccgt ccggttccac tcgacgggcg ctgaggtccc
    20761 cgtcgaggag aaagggcagg gtcagggcca gcaccttgga cttgccggtg ccgttgttcc
    20821 cccggagcag cagcctgccg tcgcggaagt ggaattcctc cacgtcgtag tggaagaggt
    20881 cgacgagacc gatccgcagg ggctgccagc gggggcgcgc aggggcgggg ggtgcgggac
    20941 ggggggtcaa ggccggtacg cctttcgctg cgcgggcacc tgcgcggtgc cggctgtacg
    21001 gggttcgagt acgacggtct cgccgaccgc gtagcgggcg agcgccgggc gcggcacgac
    21061 cctgtcagca gtgcgggcga ccaggccgag agcggccagc cgggcaatgg cctgctcggc
    21121 caagtcagcc tcggcccccg gctcacgggc cgatttggac cagaatccgc tgtgctccgc
    21181 cgccagttcg accacgcggc gctcaagatc ggtcatgggg acgaccacgc cgccgaccgc
    21241 cgtgaggtac tcggcgagca ggagggtgac gtggccgcgg gtacctgatt ccggcatgcg
    21301 gacgtcggtg aggtcgtcct cggggtcgac catggcgatg ccttcggccc gcacttcggc
    21361 gaccagtccg gtcagttcgt tgatgcgggc ggtgaggaag ccgcgctggc gcgtgaggta
    21421 gccgagttcg gcgtcggtca gctcgtcgta gtagaggacg gggtcgtcga gcagccgccg
    21481 ggtcagcgag cggcgcatgg cgcggaagcg cagttcgtcg ctgtcgaggg ccgtttccgc
    21541 ggcgagctcg gtgagccggg catccagcgt ttcggcccgg acggtggagg gtccccggcg
    21601 ggtggcgagc agacctgcga gaacccgccg ttcgacgtcg tacaggacgt cgccggctcc
    21661 actgacgtac gcgtcctcgt ctccggcgac gcgccgcagg actccgaggt ggagcaggag
    21721 ccgtacgacg gcggccaggt cgagccgctc gtcacggcgg tccagcgtga actggatgcc
    21781 cgccgcggcc agccgggggt ccttggcatc cagcatgatc tggtcggcga ggcggcccag
    21841 cgcgatctgt gcttcgccgc gttcgagggc ggcgagggcg aggcagagca ggacgtaccg
    21901 acggcggctg aaggggacgg cgctacgggt gacctcgcgc gccgggtgcg tggcgtcgtc
    21961 cggcacaccg gggatcttgc ccagtcgggc ggtctcggca tccacctgga gggaccagcc
    22021 ggtgtttcgg tcgaaccagt cgcgcagctc ggaggcgtgc cgccggacga ggcggaactc
    22081 gtcggcgtac gcgccgtgtg cgagcagcag gggctgcttc aggagggcac gggcggcctt
    22141 gcgccgctcg gcggcgtgct gcccgtcgag tacttcggcg agcggggtcg tcatcacgcc
    22201 tcgctccctc ctgttctttc ggtgaggtcg acgatctcga tggtgtggtc cgggccgcgg
    22261 aaggtcccgt ccggtgtgcg gacctcggcg atggacccgt cggtcggtgc cgtgagccgg
    22321 atctccatgg agccgtcgcc gctggtggcc gcggtgtgcg tcataccggg ccgccaggtg
    22381 gccagcgcgt cgccgaggag ctgcaggaag agccggaagc tgagggggtc gagctcgccg
    22441 agtccggaca gtgtggtgat gccgtgcgta acgagccggg cccgggcggc cgctgtctcg
    22501 gcggcctgct tggcggccgt ctcggcgagc agtcggcgcg cttcctgccg gtcctctacc
    22561 ttgcggggtt tgccgcgccg ctcgtagctt cccgtgcggc gcagctgcgg gctgatccgc
    22621 agcggcgcgg catcggccca tgcggttccc gcgggctcgg gacgggcgtg gcgggcggcc
    22681 agcgtctccg catccacggt caggtgccgg gccgggtaca gcccgaaggc ggtgcgccac
    22741 agccggtgcc gggcgtcgtc gtcgggtgct tcggcgaacc agcgcgcaag ggtacggaag
    22801 tcggcggagc ggtccgaacg ccctgcacgc cgctcgttca gcgaccgtac gacggccagc
    22861 agctgcggga tcgcgcccag tgcccggccg cgcagcagcc gggcctgcga ctcccggccg
    22921 tcccggctga ggaaccagga cgccagcccc gcccaccggc cggcccaccg ctcgtacgcg
    22981 gcctgccccg cgtacgccgc ctcctgcggg gtcgcgtccg ccgcctcacg ggcggccgcg
    23041 gcccgcaaca gccgctcgat gctcccgccc tcctccaact ccaggatcag ccgggcgatc
    23101 cgcccgccga gggtgatcag gtcctggatg aaccgctcca ggtactggat gagctggtcc
    23161 ttgtaggcga ggaagacctc ctcccccacg tcgtgaaggt cgatggtccg ctggagcgaa
    23221 cccatgaagg cccgtgcgtt gtcggcgagc gcaccgaaac ggctcgcgag cccgtccagc
    23281 gccagatgcg tcttggccgg atcaggctcc tcctcggccg tcagcacgag cagggcccgc
    23341 agctgcgtca cgatgtcgtg cagcgcgacg gcctgcagcg cgccccgccg cccgagcgcc
    23401 tcgtcgtacg cggacagagc ctcctccgcc gcctcgccct cccgcgtgag ctggtagatg
    23461 aaccgcttgc ggtagaaatc ctcgacggcg gtgacccgcc cggtgtccgg gtcagcgcgc
    23521 aggttccccc accccaccag gctgtcgagc gccttgacca cggcgtcgag ctccgtcggc
    23581 cggaccccgg aggccagccc cgcgtacacg tcctctggcc gcagatgcac ggcgaaccgc
    23641 tctttggcga cgaggaaggc ccgcatcacc gcccggtaga gcagcacgtt cggagcagtg
    23701 agatgcgcga aaggcccgta cccgtcgggc gtaccctccg cctgcggaga agtcatgtcc
    23761 attgctcgcc atcctcctgg agggcggtcc atgatcggca gggacttgag tacttggccg
    23821 attcacatcg gtccctttcg ggtccggccg caggcgacgt caccagaaac gctggaggac
    23881 gcccgtgcgc tggagctccg acacgtgttc ggcggcccgc gccggcgcgg agccccctct
    23941 gatgagtgtt ccggcctcga tgttgcggtc cactccggat tgcgtgaagt tggcgctggt
    24001 ggtcagcagc gtctgtcggt cggccacggc cagcttcgcg tgcgccttgg ccccgagctc
    24061 cgccctcttg tccaggggcc agtgccacag gcgcgctccc ggaacatcgg tgaacgcgct
    24121 cgccggctcg tccccggaaa gggcgctgcc cgcgccctgc agcgtctcga cgacgatgtc
    24181 caggccgacg ccccgggccg cggcatcctg caacaccgcc gtcagaggcg ggtaccgccg
    24241 tgccgaatag gtcatcagga tcagctcggt ccgtgcctcg gcgatcagcc ccaggagcac
    24301 ccggtccgtg gaccgtacgg gcacccggtg ggaggagggg ccgctccaca ccagggagac
    24361 ctcttgttcc cggtcgcgct gcgcgtagcc ggcggccagc ccgtgcaggc aggccgccgc
    24421 ttccgcccgg gacaggccgt ccgcgtccat cgcatcgagc acggcagccg cggcctccgt
    24481 gtaggtggag gccgaccgga ccgtgagcag cgtggcgcgg ggctgtccgg ccgctatgcc
    24541 gtcggccagt gcgcccagcg cgaggactcc tgcggccgcc tctgcctccg cggcggcctt
    24601 gagcagccgt gcccatctca cttcaggccc tggaggagca cgaggtccgg gtcgtcgatg
    24661 gggactatga accgtcggtc caggaagcgg ttgccgcgct cacaggtcgt ctccgacacg
    24721 aacaggcata cgtggcatgc ggcgccgtgc aggaagtcct cgtgcggagg ccgaggcagc
    24781 cgg
//
