LOCUS       NZ_BMVL01000008        20630 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence08, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000008
VERSION     NZ_BMVL01000008.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 335066)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 261637
            Orig. end                         :: 282267
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20630
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20630
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20630
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10630](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10630
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            423..1511
                     /locus_tag="IE257_RS22760"
                     /old_locus_tag="GCM10010343_47140"
     CDS             423..1511
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557924.1"
                     /locus_tag="IE257_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47140"
                     /product="DNA alkylation repair protein"
                     /protein_id="WP_189971416.1"
                     /transl_table=11
                     /translation="MPTADELLSAETVTTLARLLARAGGRRSSPALRARADALDGLSYS
                     ERVTAVRDAVLDDLPAEWPAFEAVVRTALAGRGFEGWMTFPVNEAVAVRGLEVFEPGLD
                     LLHDLTSRLTAESAVRPFVRADPARALAVVQKWTTDPDPHVRRLASEGTRPRLPWAAQL
                     PAFVADPRPALPVLDALYRDGSEYVRRSVSNHLNDISRDHPALAVETAARWLAAPEATT
                     DRVVRHGLRTLVKAGRPEALTLLGHSPDVPVSVSGPVVATPEVAVGEYLVFDWAVTNTG
                     PLSAELVVDYVVHHAKANGARTPKVFKLVTRALSPGETLSGTKRHSFKPITTRRYHSGE
                     HLVQLQINGRVRGEAAFSLDAS"
     misc_feature    complement(1542..1556)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.45"
                     /tool="antismash"
     gene            1566..3404
                     /locus_tag="IE257_RS22765"
                     /old_locus_tag="GCM10010343_47150"
     CDS             1566..3404
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982328.1"
                     /locus_tag="IE257_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47150"
                     /product="hypothetical protein"
                     /protein_id="WP_189971417.1"
                     /transl_table=11
                     /translation="MSAREERAALTPGTSLHDYALFLHGIEPDGRIPAGGYPLPDGSPP
                     VGRRNRLGRTAAEAAVTEAVVPLLADRVSARSAAAVQSRLAELPVPPQHIHRIVLGIVP
                     EDGHTGRARRLARRLIRTGTHPSAVHAGLALLSGLGDTTDTPAVQALGMLREFSSDAVA
                     VLDRIDRRAAAELELRITAGAPGPGTFLDAVTAGDREAVRAALTGDSTATAQGPPRRIA
                     EAARLDELLDEYPQDPDLTLAAGRLLLAMAHTSQYRPQVLDYARARPVYEAVVGGAPRL
                     TPSPDSYALLLALAQDLRSGAGAVLQWPRGRRAELLDALGRLLAEPLWAAVPDEAATAA
                     RLRPGKEPGGHRAGWMLRAERRPFTPPGAPATFEIEVVVSDPAVRNVVETRIVLGGRPL
                     VPDLFASGGSNSPESLLDAGRLRAGPEPREVKLAEAYCTEGCCGALYVTIRRDGDTVVW
                     DGWRGVEGKRQPPAYRCDAAAYDAEVQRAENDRSWSWPARDTARLIADGLRERPELLTA
                     WDCRAGGAFTAWDDPETVELLFTYAPGTGPGVPGEGAPWLQFAWRIPDDGTPPTSQARA
                     ALERLAAQNPRTWARLCGGSKEYAEALGHDWPPGGP"
     gene            complement(3475..4944)
                     /locus_tag="IE257_RS22770"
                     /old_locus_tag="GCM10010343_47160"
     CDS             complement(3475..4944)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552178.1"
                     /locus_tag="IE257_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47160"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_189971419.1"
                     /sec_met_domain="Aldedh (E-value: 1.8e-158, bitscore:
                     522.1, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEVPQPLYIGGERVEPAGGHYEVIDPADESVVGLAPEASRAQVE
                     EAARAAADAFESWSRTTPEARAAILDRAADIMQREFEPWSALARAETGAPTGIARGMQV
                     GVGVARFRRYAKGALEPVERGLPPQVTEAGPMGRASILGALEVRQPVGVITCITSYNNP
                     WANPAGKVAPALAMGNTVVVKPAPQDPLSVFRMADALHEAGVPAGVVNVVGGRSVEVGE
                     AAVDSPHVDMVSFTGSTAVGQRIAEVCGRSMKRQLMELGGKGAAIVFEDADLDAAVMGI
                     GTTFSFYSGQICTAPTRVIVHRSVHDRLIEKLTGYLAFMKVGDPAEAGTVVGPVISAAH
                     RDRVESYVELGKKEGARIAYGGERPVVGDGRGFYVAPTLLVDCTNDMRVVREEIFGPVV
                     VVVPFDGDEEEAIRLANDSDFGLLSYVWSGDSARAFRVARRLRAGGVGVNTIGRNMEAP
                     FGGFKRSGVGRDVGSYALHAYSEMQSIVWTA"
     gene            complement(4941..6680)
                     /locus_tag="IE257_RS22775"
                     /old_locus_tag="GCM10010343_47170"
     CDS             complement(4941..6680)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552179.1"
                     /locus_tag="IE257_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47170"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_189971421.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 7.6e-09, bitscore:
                     29.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHHLIKGATVVDGTGAPARVADLGIRDGRIAVIAEPGTVTEEAR
                     TTEDATGLVLTPGFIDPHTHYDAQLFWDPYATPSMNHGVTTVAGGNCGFTLAPLNPARP
                     EDADYTRRMMSKVEGMALKALEEGVDWTWSTFGEYLDALEGRIAVNAGFMVGHCALRRH
                     VMGEDAVGGQPTPEQMQQMLDLFHDAMNAGAWGLSTTQSSTHSDGSGAPVASRHARPAE
                     LLALSEAVAEHEGTQLEAIVAGCLDQFSDDEIDLFVEMSAAAGRPLNWNVLTIDASVPE
                     RVPRQLIPSERARKAGGRIVALTMPILTPMNMSLGTFCALNLIPGWGEILALPVPERIA
                     KLRDADVRAEMLRRADSKEAGVFRRLANFGRYVIGDTYSKENEGLSGRVVNDIAAERGQ
                     DPFHCLVEICANDELRTVLWPMPTDNDPASWALRQETWQHEDVMLGGSDAGAHLDRMCG
                     APYTTRFLGDCLRGRKLVPLEQAVRMLTDDPARLFGLRERGRLAEGFHADLVLFDPERI
                     EAGPATLVHDLPGDSPRLDARAIGIVSVRVNGVETIRDDEVTGAVPGIVLRSGRDTRTV
                     STR"
     assembly_gap    6708..6725
                     /estimated_length=18
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6845..7966)
                     /locus_tag="IE257_RS22780"
                     /old_locus_tag="GCM10010343_47180"
     CDS             complement(6845..7966)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740712.1"
                     /locus_tag="IE257_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47180"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_189971422.1"
                     /transl_table=11
                     /translation="MEFGLFVQGYVPEARSKVDPEAEHKALIEETEYVIQADRSGFKYA
                     WASEHHFLEEYSHLSANEVFLGYLAHATERIHLGSGIFNPLAPVNHPVKVAEKVAMLDH
                     LSKGRFEFGTGRGAGSHEILGFLPGIEDMNGTKEIWEETIAEFPKMFLQEEYEGFQGKH
                     WSLPPRKIFPKPYGKAHPAMWYAAGSPSSYAMAAKKGLGVLGFSVQKVSDMEWVLDQYK
                     TAIREAKAIGAFVNDNVMVTSTAICAETHDKAVEIAVNANMNRFQSLVFRYHDTFPRPE
                     AIPQWPETLPEYNAEIIELLIAEELLICGDPSEVRAQCKRWEQAGADQLSFGLPTGVSP
                     EDTMTTIKLIGEHVIPHIDTDPVHRTTRFRQAV"
     gene            complement(8062..8847)
                     /locus_tag="IE257_RS22785"
                     /old_locus_tag="GCM10010343_47190"
     CDS             complement(8062..8847)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-164). E-value: 6.4e-11. Score:
                     34.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS22785_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740713.1"
                     /locus_tag="IE257_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47190"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_189971424.1"
                     /sec_met_domain="adh_short (E-value: 2.9e-31, bitscore:
                     103.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLDGRVVIITGAARGQGEQEARLFAAEGASVLLGDVLDEQGAA
                     VAKDIGEDRARYVRMDVSREEDWAAAIAVAKATFGPIDGLVNNAGILRFNELTATPLEE
                     FQQVVQVNQVGAFLGIKTVAPEIEAAGGGTIVNTSSYTGLTGMAYVGTYAATKAAILGL
                     TRVAALELAGKGIRVNAMCPGAVDTPMANPGLLDPANLTDEARDAMAELYKRVVPMGRV
                     GQPEEIAKLALFLTGEDSSYITGQPFVIDGGWMAGVSIL"
     aSDomain        complement(8356..8826)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS22785_PKS_KR.1"
                     /evalue="6.40E-11"
                     /label="IE257_RS22785_PKS_KR.1"
                     /locus_tag="IE257_RS22785"
                     /protein_end="164"
                     /protein_start="7"
                     /score="34.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVIITGAARGQGEQEARLFAAEGASVLLGDVLDEQGAAVAKDIGE
                     DRARYVRMDVSREEDWAAAIAVAKATFGPIDGLVNNAGILRFNELTATPLEEFQQVVQV
                     NQVGAFLGIKTVAPEIEAAGGGTIVNTSSYTGLTGMAYVGTYAATKAAILGLT"
     gene            complement(8861..9808)
                     /locus_tag="IE257_RS22790"
                     /old_locus_tag="GCM10010343_47200"
     CDS             complement(8861..9808)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961425.1"
                     /locus_tag="IE257_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47200"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_229920591.1"
                     /transl_table=11
                     /translation="MARVFPEGRLVHGMQLPVQSQSTLYAEPWEASATAVDLAEIARAA
                     DRAGFGYLATCDHVAIPRRLAGPMSTVWYDPVATLSFLAGITEHVRLLSHVAILGLRHP
                     LISAKQYATLDHLSGGRLVLGVGAGHVQEEFEILGVDFARRGAVLDETLDALRRALGPE
                     EYPEFEGELFSFKDLGQLPRPAQERIPVWVGGSSPAAVRRAAVRGDGWLPQGDPRDRLP
                     QQIARIRELREAAGVTDPIEFGAITEALYVGEPGWDTGRRTLTGKAEALAESLREYRAL
                     GVDQIQVRFRSRDRAELVDQIIAFGAEVAPLLND"
     gene            10001..10630
                     /locus_tag="IE257_RS22795"
                     /old_locus_tag="GCM10010343_47210"
     CDS             10001..10630
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TS_Pyr4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265765.1"
                     /locus_tag="IE257_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47210"
                     /product="hypothetical protein"
                     /protein_id="WP_229920609.1"
                     /sec_met_domain="TS_Pyr4 (E-value: 7.9e-25, bitscore: 81.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLVSGIAWTVVYVEAIRVGLRDRTYAMPVAALALNFAWESTYA
                     VRELSVGVSAQGVVNVVWAVADLAIVYTYLRFGRAELPEFVTRPLFATWSVLIFGTGFA
                     VQWLFLAHFGMHDATRYSAFLQNLLMSGLFIGLYTARQGPHGQSLTIAVAKWLGTLAPT
                     LLFGVVEDAPFILGLGILCSVFDLAYIGLLLRPRFARVRSLPAPSR"
     gene            complement(10602..11435)
                     /locus_tag="IE257_RS22800"
                     /old_locus_tag="GCM10010343_47220"
     CDS             complement(10602..11435)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525658.1"
                     /locus_tag="IE257_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47220"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_229920592.1"
                     /transl_table=11
                     /translation="MSKHARARSRPSGKPRPIRRTRRVALAAALGLATFTAGWAYLAQD
                     QDKAAAARPQARADARPQAADRAARDAQREAARRAAAEQGLTGVSEHTRARIPAESRQL
                     ILVTGRAVDSSESTAAFYTRPAAGADWVRTESWPARNGANGWSVEREYGDLTSPQGVFA
                     LTDAGGLLPKPPGTRFPYDRDNGFVATGLGVNGESLAGSFDYVVAIDFNRRPGRSPLDP
                     VMPDGEDKGGNIWLHVDHDGPSQGCVGIPKDAMKKVLETLDPAAKPVIVMGPAGF"
     gene            complement(11477..12754)
                     /locus_tag="IE257_RS22805"
                     /old_locus_tag="GCM10010343_47230"
     CDS             complement(11477..12754)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009999496.1"
                     /locus_tag="IE257_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47230"
                     /product="ATP-binding protein"
                     /protein_id="WP_229920593.1"
                     /transl_table=11
                     /translation="MRLRRGTRLRPTRSGPSTGLLRTERGRLTALYGSLLLLAGGGLVA
                     LVYLLVGQGLYASVNGAVRTVSPGYVLQSPGPVPGRTFAPDCPCEPARKLPPGQTPTPE
                     QLKSYAYTQNLSDAVTDATRHRLLMYSLLALAVFAVLSIWLAWWMAGRVLRPVGVITET
                     ARRLSGENLDERISLDAPPGELKQLADTFDAMLGRMEQLVSAQRRFAANAAHELRTPLA
                     VQRAAAEIGLAGDPSPEKVARIRDRLIGVADSSEHLIESLLLLAVSEQGLESTAPVDLA
                     ALAAAELAACPQQGLTVVRTLAPLAVPGDRTLLGHLLRNLLINAVRHNRDGGRIAVSTS
                     TQGELTVSNTGPVIDPADVPGLLEPFRRRAERQHTAGEGAGLGLSIVASIARAHGAELS
                     AEANPAPGGGLTVRVRFPSSDEARTS"
     gene            complement(12826..13488)
                     /locus_tag="IE257_RS22810"
                     /old_locus_tag="GCM10010343_47240"
     CDS             complement(12826..13488)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641777.1"
                     /locus_tag="IE257_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47240"
                     /product="response regulator transcription factor"
                     /protein_id="WP_030390073.1"
                     /transl_table=11
                     /translation="MRVLVVEDEEFLREMIAEGLRRDALAVDEASDGPEALRLLRLGEY
                     DVLVLDRDLPGLHGDEVCRQVVRERLLTRVLMLTASGTVRDRVEGLGLGADDYLTKPFA
                     YDELLARVLALGRRARPALPPVLERAGVAVDTARRSATRDGHRLALSRKEFAVLEALLR
                     AEGAVVSNDDLIEQVWEQDTSYSTNAVRVTLSKLRAKLGEPPLIETVPGAGYRIAAR"
     gene            13579..14079
                     /locus_tag="IE257_RS22815"
                     /old_locus_tag="GCM10010343_47250"
     CDS             13579..14079
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE257_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010343_47250"
                     /product="hypothetical protein"
                     /protein_id="WP_189971428.1"
                     /transl_table=11
                     /translation="MKRSLIMTTAAVVTGLTLFATACANDASAGKKDSSGGSSGTGSGS
                     SGGDGSVADNAVKMRQCLREHGIDVPDPEPGQDPRGMTLGGDADPQKMQEAMKACGMST
                     GAGKEPTQEEKDKELEWIRCMRENGVALKDPEYNGGMKSATEIPKGQEKAFEEAQKKCE
                     TAR"
     gene            14076..15179
                     /locus_tag="IE257_RS22820"
                     /old_locus_tag="GCM10010343_47260"
     CDS             14076..15179
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126694.1"
                     /locus_tag="IE257_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47260"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_189971430.1"
                     /transl_table=11
                     /translation="MRKRSKWLLGSLAAVLAVSGGGWAVIDRQQGDTDGQERRAAGGLP
                     PATAPVERGDLGSGLQVEGTLGYAQERKLNAGGPGVLTWVAGEGSAVERDGKLYEVNGR
                     PVRLMYGSTPMYRPLKAGDKGEDVKQLKRNLQALGHGTGLDPEDGVFTAGTATAVKRWQ
                     KAHRAAETGEVGKEDIAFASGPQRVRGNDAAVGDEVGPGKPVLTVTGTERIVRFQLEPA
                     KAGAVKSGDPVTMRLPGGGGATGKIDSVGGAAQPDDKNGGGAGGPGGGDKKAEVEVIVT
                     FDRPAEVNAPDQSPVTVGLTGETRKGVLSVPVNALLALAGGGFGVQVVQDGRAREVPVE
                     LGMFGNGRVEVTGDALKEGMQVGIPKL"
     gene            15185..15949
                     /locus_tag="IE257_RS22825"
                     /old_locus_tag="GCM10010343_47270"
     CDS             15185..15949
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551984.1"
                     /locus_tag="IE257_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47270"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_189971432.1"
                     /transl_table=11
                     /translation="MTRAHLTTHPTTLPATHPATGPTARPDTVVELTGVTKEYPGGVAA
                     LRGVDLTVTAGELLAIVGPSGSGKSTLLHIVGTLDRPTAGGVRIAGYDIAALSDRSLSA
                     LRSRHVGFVFQSFHLVPGISARANVAEGLLYSGLSRAERLRRAAEALERVGLGDRMDHR
                     PHELSGGQKQRVAIARAVAGAPDLLLADEPTGALDTASGESVMELLRELNRDGATIAVI
                     THDQEIAASLPRQVRIRDGEIVADRSPAGVAS"
     gene            15946..17172
                     /locus_tag="IE257_RS22830"
                     /old_locus_tag="GCM10010343_47280"
     CDS             15946..17172
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764614.1"
                     /locus_tag="IE257_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47280"
                     /product="ABC transporter permease"
                     /protein_id="WP_189971434.1"
                     /transl_table=11
                     /translation="MSRARARTRTQVRRLTPPRLSPRDVLHVGSAGLRARPMRVFLSAL
                     GIAIGIATMIAVVGISSSSQAELLRELDRLGTNMLVAKPGEGMFTGQDTRLPKDAPGMI
                     SRIAGVESVGTTGDVAESVRRSENIPKGETGGIVLKAAKDDLLGTLRARMASGTWLNAA
                     TGRFPSVVLGDVSARRLGITEPGQQVFIGGRYFTVIGILEPVPLAPEIERSALIGWDAA
                     EQLLGFNGHPTAVYERSADDRVAAVRTLIPRTANPQTPSAVQVSDPSAALQAKAATEGA
                     FSTLLLGLGGIALLVGGVGVANTMIISVLERRHEIGLRRSLGGTKGQIRIQFVTESLLL
                     SGLGGLAGIALGGAATAVYARAGDLPWVVPLWAVTGGFASTLVIGTLAGLYPAVRAARL
                     SPTLALAAG"
     gene            17280..17723
                     /locus_tag="IE257_RS22835"
                     /old_locus_tag="GCM10010343_47290"
     CDS             17280..17723
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265757.1"
                     /locus_tag="IE257_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47290"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_189971435.1"
                     /transl_table=11
                     /translation="MRRTPRHAARVVILSPTGSVFLFREDNVEVGIHWLPPGGGIDPGE
                     SPEDCVRRELREETGWTDLEPERLLCTWEHDFTYQGVPVRQHEHIYVTTGPRREPVLEA
                     PDIHWRWLSPQRLAALGEPVWPPRLPDLLADIPAQPVHLGLLA"
     gene            complement(17773..18624)
                     /locus_tag="IE257_RS22840"
                     /old_locus_tag="GCM10010343_47300"
     CDS             complement(17773..18624)
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265753.1"
                     /locus_tag="IE257_RS22840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47300"
                     /product="serine protease"
                     /protein_id="WP_189971438.1"
                     /transl_table=11
                     /translation="MPVDKRTVVTAVLCAVAALGASAAVAKLVPPPEAVPSARAKAAPT
                     ASPTGPSSRSQAAKPQLSAPPGSTLPPAVTPPPGGPAAFTGALFTDGLNSDHFCTATVV
                     SSPGRNMIITAGHCLLEGDQSGGSAVFAPAYANGVAPYGTWKIEQVFEDDRWAEGTDDD
                     YDLAFARLAPDDKGRTVEDVTGAAVLDTSGRAGEEVTVTGYPADRGVPRTCTSVAVRES
                     ATQQRFDCADFPGGTSGSAWIARDGKIIGILTGGDTDDVSTSTVLGEYAASLYAKATAK
                     KP"
     gene            complement(18709..19203)
                     /locus_tag="IE257_RS22845"
                     /old_locus_tag="GCM10010343_47310"
     CDS             complement(18709..19203)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555815.1"
                     /locus_tag="IE257_RS22845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_47310"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189971439.1"
                     /transl_table=11
                     /translation="MPELQPLSFDHAPALLAFERENRAYFAAAVPDRGDRYFADFDERH
                     AALMAEQATGACFFHVLVDGAGEVVGRVNLVDVADGSAELGYRIAERATGRGLATAAVR
                     KACGLAVTQYGLTALRAVTTLDNAGSRAVLARTGFVPVGGVDLDGRPGLRFVCNLQVET
                     V"
ORIGIN
        1 cgtcaccgaa atcggctact gcggcaggcg gggcatcacg accatcgccc tgatcaagga
       61 tccgaaggcc ttccagacgg ccttcaaggc ccaggtcgac gcgaagaagg gcagcgggaa
      121 ccccgacagc ggcatcgtcg tcggacagga cttcgccatg ggatccgaga gctcggacgc
      181 catgagtgcc ctgctccagc cgcaggccgg gctgctcatg ctcaactgcc acgccgactt
      241 caacccgccg agcgggtacc gcaaggagcc cgccctggtg aagggctgcg tcctcacgga
      301 ctactacaag gactgagcgc caccggacgg gccgcggccc cgggtcccag ggccggggcg
      361 cgggaccggg gcccggaaga actccggccc ggaaccgggg gttcatccgt gagactgggc
      421 ccatgcccac ggccgatgag ctcctcagtg cggaaaccgt caccaccctc gcccgactgc
      481 tcgcgcgcgc gggcggccgc cgctcctcgc ccgccctgcg ggcccgcgcc gatgccctcg
      541 acggcctgag ctacagcgag cgcgtcaccg ccgtccgcga cgccgtgctc gacgacctcc
      601 ccgccgaatg gcccgccttc gaggccgtcg tgcggaccgc cctcgccggg cgcggcttcg
      661 aggggtggat gaccttcccc gtcaacgagg ccgtggccgt ccgcgggctg gaggtgttcg
      721 agccgggact ggacctgctg cacgacctga cctcccggct gaccgccgag tccgccgtac
      781 ggcccttcgt gcgcgccgac ccggcccgcg ccctggccgt cgtacagaag tggaccaccg
      841 acccggaccc gcacgtacgc cgcctcgcca gcgagggcac ccggccccgg ctgccgtggg
      901 ccgcgcagct gcccgccttc gtcgccgacc cgcggcccgc cctgcccgtg ctggacgcgc
      961 tgtaccggga cgggtccgag tacgtccgcc ggtccgtctc caaccacctc aacgacatca
     1021 gccgcgacca ccccgccctc gccgtcgaga ccgcggcccg ctggctggcc gcgcccgagg
     1081 ccacgacgga ccgcgtcgta cggcacggcc tgcgcaccct ggtcaaggcc ggccgacccg
     1141 aggcgctgac cctgctcggg cactcccccg acgtgccggt gagcgtgagc gggccggtcg
     1201 tcgccacccc ggaggtcgcc gtcggcgagt acctcgtctt cgactgggcg gtcaccaaca
     1261 ccggcccgct gtcggcggag ctggtcgtcg actacgtcgt gcaccacgcg aaggcgaacg
     1321 gcgcccgcac cccgaaggtg tttaagctcg tcacccgcgc gctgtccccc ggcgaaaccc
     1381 tcagcggcac caagcgccac tccttcaaac cgatcaccac ccgccgctac cactccggcg
     1441 aacacctggt tcagctccag atcaacgggc gggtccgcgg cgaggccgct ttttcactgg
     1501 acgcgtcctg accccgcctg gcaccctccc gtcatgacct atggaatcga gtcccacccc
     1561 gcccgttgag cgcccgcgag gagcgcgcgg cgctcacccc cggtacctcc ctccacgact
     1621 acgccctctt tctgcacggc atcgagccgg acggccggat cccggccggg ggatacccct
     1681 tgcccgacgg ctccccgccc gtcggccggc gcaaccgtct cggccgcacc gccgccgaag
     1741 cggcggtcac cgaggccgtc gtcccgctgc tggccgaccg ggtcagcgcc cgttccgccg
     1801 cggccgtcca gtcacggctg gccgaactcc ccgttccacc gcagcacatc caccggatcg
     1861 tcctcgggat cgtccccgag gacgggcaca ccggccgtgc ccggcgcctg gcccgtcggc
     1921 tgatccgcac cgggacgcac ccgtccgcgg tccacgccgg gctggccctt ctgtccggtc
     1981 tcggtgacac caccgacacg cccgccgtcc aggccctcgg catgctgcgg gagttctcct
     2041 ccgacgcggt ggccgtcctc gaccggatcg accgacgggc ggcggccgag ctcgaactcc
     2101 gcatcacggc cggggcaccc gggccgggca ccttcctcga cgccgtgacg gccggggacc
     2161 gcgaggcggt ccgcgccgcc ctgaccggcg actccacggc cacggcgcag ggcccgcccc
     2221 gccggatcgc cgaggccgcc cggctggacg aattgctcga cgaatacccc caggacccgg
     2281 acctgaccct cgcggcgggc cggctgctgc tcgccatggc ccacacgagc cagtaccggc
     2341 cgcaggtcct cgactacgcg cgggcccgtc ccgtgtacga ggccgtggtc ggcggagccc
     2401 ctcggctcac cccgtcgccg gactcgtacg ccctgctgct cgcgctcgcc caggatctgc
     2461 gcagcggggc gggggccgtt ctgcagtggc cgcggggccg gcgggccgaa ctgctcgatg
     2521 ccctgggccg gctgctggcg gaaccgctct gggcggccgt acccgacgaa gcggcgaccg
     2581 ccgcgcgcct gcgccccggc aaggaaccgg gcggccaccg ggccggctgg atgctccgcg
     2641 ccgaacgccg accgttcacc ccgcccggcg caccggccac gttcgagatc gaggtcgtcg
     2701 tctccgaccc ggccgtgcgc aacgtggtgg agacccggat cgtgctcggc ggcaggccgt
     2761 tggttcccga cctgttcgcc tcgggcggct ccaactcccc cgagtccctg ctcgacgccg
     2821 ggcggctgcg ggccggtccc gaaccccgcg aggtcaagct ggccgaggcc tactgcaccg
     2881 agggctgttg cggggccctc tacgtgacga tccgccggga cggcgacacg gtggtgtggg
     2941 acggctggcg gggcgtcgag gggaagcggc agccgcccgc gtaccggtgc gacgccgccg
     3001 cgtacgacgc ggaggtccaa cgggccgaaa acgaccggag ctggtcctgg cccgcgcgcg
     3061 acaccgcccg gctcatcgcc gacgggcttc gggaacgccc cgagctgctc accgcctggg
     3121 actgccgcgc gggcggggcc ttcaccgcat gggacgatcc ggagaccgtc gaactcctct
     3181 tcacctacgc ccccggcacc ggacccggag taccgggcga gggcgccccg tggctgcagt
     3241 tcgcatggcg gatcccggac gacggcacac cgcccacatc gcaggcccgg gccgccctcg
     3301 aacggctcgc ggcgcagaac ccgcgtacct gggcccggct ctgcgggggc agcaaggagt
     3361 acgccgaggc cctcggccac gactggccgc ccgggggccc gtaggccgtc tgccggggcc
     3421 ccgccacggg ggccccggcg tccggggggc tacgccgtcc aggcgtccgg ggggctacgc
     3481 cgtccagacg atcgactgca tctcgctgta ggcgtgcagc gcgtacgagc cgacgtcgcg
     3541 gcccaccccg ctgcgcttga acccgccgaa cggcgcctcc atgttgcggc cgatggtgtt
     3601 cacgccgacc ccgcccgccc gcagccgacg cgccacgcgg aacgcgcgcg ccgagtcccc
     3661 ggaccacacg tagctcagca gcccgaagtc gctgtcgttg gccagccgga tcgcctcttc
     3721 ctcgtcgccg tcgaagggca cgaccacgac caccgggccg aagatctcct cgcgcaccac
     3781 ccgcatgtcg ttcgtgcagt cgacgagcag ggtcggcgcc acgtagaagc cgcggccgtc
     3841 cccgaccacc gggcgctcgc cgccgtacgc gatccgcgcg ccctccttct tcccgagctc
     3901 gacgtacgat tccacgcggt cgcggtgcgc ggccgagatc accgggccga cgaccgtgcc
     3961 ggcctccgcc gggtcgccga ccttcatgaa ggccaggtag ccggtcagtt tctcgatcag
     4021 ccggtcgtga accgaccggt ggacgatcac ccgggtcggg gccgtgcaga tctgcccgga
     4081 gtagaaggag aaggtcgtcc cgatccccat caccgccgcg tccaggtcgg cgtcctcgaa
     4141 gacgatcgcc gcgcccttgc cgcccagctc catcaactgc cgcttcatgg accggccgca
     4201 gacctcggcg atgcgctgcc cgacggccgt ggaaccggtg aaggacacca tgtccacgtg
     4261 cggggagtcc accgcggcct cgccgacctc caccgaccgg ccgcccacga cgttcaccac
     4321 gcccgccggc accccggcct cgtgcagggc gtccgccatc cggaacaccg acagcgggtc
     4381 ctgcggcgcc ggcttcacca ccaccgtgtt gcccatggcc agggccgggg ccaccttgcc
     4441 cgccggattc gcccacgggt tgttgtagga ggtgatgcag gtgatcacgc cgaccggctg
     4501 gcgcacctcc agcgcgccca ggatgctcgc ccgccccatc gggccggctt ccgtgacctg
     4561 cgggggcagg ccccgctcga ccggttcgag ggcccccttc gcgtaccgcc ggaagcgggc
     4621 gacgcccacc ccgacctgca tgccgcgcgc gatcccggtc ggcgcacccg tctcggcccg
     4681 ggccagtgcc gaccacggct cgaactcccg ctgcatgatg tccgcggccc ggtccaggat
     4741 cgccgcccgc gcctcgggcg tcgtacggga ccagctctcg aaggcgtcgg ccgcggcgcg
     4801 cgccgcctcc tcgacctggg cgcgcgaggc ctcgggcgcg agcccgacca ccgactcgtc
     4861 cgccgggtcg atcacctcgt agtgaccgcc cgcgggctcc acccgctccc cgccgatgta
     4921 gagcggctgc ggcacctcgg tcatcgggta ctcaccgtcc tcgtgtcgcg gccggaccgg
     4981 agcacgatgc ccggaacggc gcccgtcacc tcgtcgtcgc ggatggtctc cacgccgttg
     5041 acgcgtaccg agacgatgcc gatggcccgg gcgtccagcc gcgggctgtc gccgggcagg
     5101 tcgtggacca gggtcgcggg tccggcctcg atccgctccg ggtcgaagag gaccaggtcc
     5161 gcgtggaacc cctcggcgag gcgcccgcgt tcgcgcagcc cgaacagccg ggccgggtcg
     5221 tcggtgagca tccgtaccgc ctgctccagc gggacgagct tgcggccgcg caggcagtcg
     5281 ccgaggaagc gggtcgtgta cggggccccg cacatccggt ccaggtgcgc gccggcgtcg
     5341 gagccgccga gcatgacgtc ctcgtgctgc caggtctcct ggcgcagggc ccagctcgcc
     5401 gggtcgttgt cggtgggcat cggccagagc accgtgcgca gctcgtcgtt ggcgcagatc
     5461 tccaccaggc agtggaaggg gtcctgaccg cgctcggcgg cgatgtcgtt cacgacccgg
     5521 ccggagaggc cctcgttctc cttgctgtac gtgtccccta tgacgtaccg cccgaagttg
     5581 gcgaggcgcc ggaagacgcc ggcctccttg ctgtcggcgc ggcgcagcat ctcggcccgt
     5641 acgtcggcgt cgcggagctt cgcgatccgc tcggggacgg gcagggcgag gatctcgccc
     5701 cagcccggga tgaggttgag cgcgcagaag gtgcccaggg acatgttcat gggggtgagg
     5761 atcggcatcg tcagcgcgac gatccggccg ccggccttgc gggcgcgctc gctggggatc
     5821 agctggcgcg ggacccgctc ggggacggag gcgtcgatgg tgaggacgtt ccagttgagc
     5881 ggccttcccg cggcggcgct catctccacg aacaggtcga tctcgtcgtc cgagaactgg
     5941 tcgaggcagc cggcgacgat cgcctccagc tgggtgccct cgtgttcggc gaccgcctcg
     6001 gacagcgcca gcagctcggc gggccgggcg tggcgggagg ccacgggggc gccggatccg
     6061 tcggagtggg tggaggactg ggtggtggac aggccccagg cgccggcgtt catggcgtcg
     6121 tggaagaggt cgagcatctg ctgcatctgc tcgggggtgg gctggccgcc gacggcgtcc
     6181 tcacccatca cgtgccggcg cagggcgcag tggccgacca tgaagccggc gttgacggcg
     6241 atgcggccct ccagggcgtc gaggtactcg ccgaaggtgg accaggtcca gtcgacgccc
     6301 tcctccaggg ccttgagggc catgccctcg accttgctca tcatccggcg ggtgtagtcg
     6361 gcgtcctcgg ggcgggccgg gttgagcggg gccagggtga agccgcagtt cccgccggcg
     6421 acggtggtca cgccgtggtt catggagggc gtggcgtacg ggtcccagaa gagctgggca
     6481 tcgtagtgcg tgtggggatc gatgaagccc ggggtcagga cgaggccggt ggcgtcctcg
     6541 gtcgttcggg cctcctcggt gacggtgccg ggctcggcga tgacggcgat gcggccgtcc
     6601 cggatgccga ggtctgcgac gcgggcgggg gcgccggtgc cgtccacgac ggtcgcgccc
     6661 ttgatcaggt ggtggagcat gacgtccctt cacgctttga gccccgcnnn nnnnnnnnnn
     6721 nnnnncccgg accccgcgcc tcaaacgccg gcgaggccgg atgtggcccc ggccggtggc
     6781 cgcccggccg gggccggtgc gggacggcgg tccgggaaga cgccgtcccc gtttccccgc
     6841 cgggtcagac ggcctggcgg aagcgggtcg tgcggtggac cgggtccgtg tcgatgtggg
     6901 ggatcacgtg ctcgccgatc agcttgatcg tcgtcatcgt gtcctcgggt gagacaccgg
     6961 tcggcagacc gaaggacagc tggtcggccc ccgcctgctc ccagcgcttg cactgggcgc
     7021 gcacctccga cgggtcgccg cagatcagca gttcctccgc gatcaacagc tcgatgatct
     7081 ccgcgttgta ctccggcagg gtctcgggcc actgcgggat cgcctcgggc cgcgggaagg
     7141 tgtcgtggta gcggaagacc agcgactgga agcggttcat gttggcgttg acggcgatct
     7201 cgacggcctt gtcgtgggtc tcggcgcaga tcgcggtcga ggtgaccatg acgttgtcgt
     7261 tgacgaaggc gccgatggcc ttcgcctcgc ggatggccgt cttgtactgg tcgaggaccc
     7321 actccatgtc ggagaccttc tgcacgctga agcccagcac gccgaggccc ttcttcgccg
     7381 ccatggcgta cgaggacggg gatccggccg cgtaccacat ggccgggtgg gccttgccgt
     7441 acggcttggg gaagatcttc cgcggcggca gggaccagtg cttgccctgg aacccctcgt
     7501 attcctcctg gaggaacatc ttggggaact ccgcgatggt ctcctcccag atctccttgg
     7561 tgccgttcat gtcctcgatg ccgggcagga agccgaggat ctcgtggctg cccgcgcctc
     7621 ggccggtgcc gaactcgaag cggcccttgg agaggtggtc gagcatggcg accttctcgg
     7681 ccaccttgac cgggtggttc accggggcga gcgggttgaa gatcccggag ccgaggtgga
     7741 tgcgctcggt ggcgtgggcg aggtacccga ggaacacctc gttcgccgac aggtgtgagt
     7801 actcctccag gaagtggtgc tcggaggccc aggcgtactt gaagccggac ctgtccgcct
     7861 gtatgacgta ctcggtctcc tcgatcagcg ccttgtgctc tgcctcgggg tcgaccttgg
     7921 atcgcgcctc aggcacgtat ccctgcacaa agagcccgaa ttccaagggg gttcaccgtc
     7981 ctttggtttc tgacgttccg tcagatctga tgtctcgact gttccatcgc cagggtgcga
     8041 gcgtcaatac ctgacgctcc atcagagaat gctgacgcct gccatccagc ccccgtcgat
     8101 cacgaacggc tggccggtga tgtacgagga gtcctcgccc gtcaggaaga gcgccagctt
     8161 cgcgatctcc tccggctgcc ccacgcgccc catcgggacc acccgcttgt agagctccgc
     8221 catcgcgtcc cgcgcctcgt cggtcaggtt cgccgggtcc agcaggcccg ggttggccat
     8281 cggggtgtcc acggcgcccg ggcacatcgc gttgacccgg atgcccttgc ctgcgagctc
     8341 cagcgcggcc acccgggtca ggccgaggat cgccgccttg gtggcggcgt aggtgccgac
     8401 gtacgccatg cccgtgaggc ccgtgtacga ggaggtgttg acgatcgtgc cgccgccggc
     8461 cgcctcgatc tcgggggcca ccgttttgat gccgaggaag gcgcccacct gattgacctg
     8521 gaccacctgc tggaactcct ccaacggggt cgcggtcagc tcgttgaagc gcaggatgcc
     8581 cgcattgttg accaggccgt cgatcgggcc gaaggtcgcc ttcgccacgg cgatcgcggc
     8641 cgcccagtcc tcctcccggc tcacgtccat ccgtacgtac cgcgcccggt cctcgccgat
     8701 gtccttggcc accgccgcgc cctgctcgtc cagcacgtct ccgaggagca ccgaggcgcc
     8761 ctcggcggcg aagagccggg cctcctgctc gccctgaccg cgtgccgcgc ccgtgatgat
     8821 gacgacgcgc ccgtccagct tgcccatggt ccgtcagccc ctagtcgttg aggagggggg
     8881 ccacctcggc cccgaaagcg atgatctggt cgacgagttc ggcgcggtcg cggctgcgga
     8941 agcggacctg gatctggtcc acgccgagcg cccggtactc ccgcagggac tccgcgagcg
     9001 cctccgcctt gccggtgagg gtgcggcggc cggtgtccca gccgggctcg ccgacgtaca
     9061 gcgcctcggt gatcgcgccg aactcgatgg ggtcggtcac ccccgccgcc tcacggagct
     9121 ccctgatccg ggcgatctgc tgcgggagcc ggtcgcgcgg gtcgccctgc gggagccagc
     9181 cgtccccgcg gaccgccgcg cggcgcacgg cggcgggcga ggagccgccg acccagacgg
     9241 ggatccgctc ctgcgcgggc cggggcagct ggccgaggtc cttgaaggag aacagctcgc
     9301 cctcgaactc gggatactcc tcggggccca gcgcccggcg cagcgcgtcc agggtctcgt
     9361 cgagaacggc cccgcggcgc gcgaagtcca cgccgaggat ctcgaactcc tcctgcacgt
     9421 gcccggcgcc caccccgagg accagccggc cgccggagag gtggtcgagg gtggcgtact
     9481 gcttggcgct gatcagcggg tggcgcaggc ccaggatcgc gacgtgactc agcaggcgca
     9541 cgtgctcggt gatgccggcc aggaaggaca gggtcgccac cgggtcgtac cagacggtgc
     9601 tcatgggtcc ggcgagccgt cgcgggatgg ccacgtggtc acaggtggcc aggtacccga
     9661 agccggcccg gtctgcggcc cgcgcgatct cggcgagatc gacggcggtg gccgaggcct
     9721 cccagggttc ggcgtagagg gtgctctgcg actggaccgg gagctgcatc ccgtggacca
     9781 gccgaccttc cggaaatacg cgcgccatgg cgggcccgcc tcgccttcgt ctgccgattc
     9841 gtcatatcgg tgccgggcca tcgtcgtagc tgacggatcg tcagacaagg ggtgcgacac
     9901 accccgcgcg gaacgggccc gatcggcagg acgggccccg gcaccggttc cgcccgttcc
     9961 cctcgcgcga tccgctcgct agggtgcgcg cgtggatctg atgctcacgc tggtcagcgg
    10021 gatcgcctgg acggtcgtgt acgtggaggc gatccgcgtc gggctgcggg accggacgta
    10081 cgcgatgccc gtcgccgccc tcgcgctcaa cttcgcctgg gagagcacct acgcggtccg
    10141 cgagctctcg gtcggcgtct ccgcgcaggg cgtggtcaac gtggtgtggg cggtggccga
    10201 cctcgcgatc gtctacacct acctgcgctt cgggcgggcc gagctgccgg agttcgtcac
    10261 ccggccgctc ttcgccacct ggtccgttct gatcttcggt acgggcttcg ccgtgcagtg
    10321 gctgttcctg gcgcacttcg gcatgcacga cgcgacccgg tactcggcct tcctgcagaa
    10381 cctcctgatg tccgggctgt tcatcggcct gtacaccgcc cggcagggcc cgcacggaca
    10441 gtccctgacc atcgccgtcg ccaagtggct cggaacgctc gcccccaccc tgctcttcgg
    10501 ggtggtcgag gacgcgccgt tcatcctcgg gctcgggatc ctgtgcagcg tcttcgacct
    10561 cgcctacatc ggactgctgc tccggccccg gttcgcccgc gtcagaagcc tgccggcccc
    10621 atcacgatga ccggcttcgc cgccgggtcg agggtctcca ggaccttctt catggcgtcc
    10681 ttcgggatgc cgacgcagcc ctgcgagggg ccgtcgtggt ccacgtggag ccagatgttg
    10741 ccgcccttgt cctcgccgtc cggcatgacc gggtccagcg gggacctgcc gggcctgcgg
    10801 ttgaagtcga tggcgacgac gtagtcgaag gagcccgcca gggactcccc gttcacaccg
    10861 agacccgtgg cgacgaagcc gttgtcccgg tcgtacggga accgggtgcc cgggggcttc
    10921 ggcagcagtc cgcccgcatc ggtgagcgcg aacacgccct gcggcgaggt caggtcaccg
    10981 tactcgcgtt cgacggacca gccgttggca ccgttgcggg cgggccagct ctcggtccgc
    11041 acccagtcgg cgccggccgc ggggcgcgtg tagaaggcgg cggtggactc cgaggagtcc
    11101 accgccctcc cggtgaccag gatgagctgg cgggactccg ccgggatccg ggcccgggtg
    11161 tgctcgctga cgccggtcag gccctgctcg gcggcggccc gccgggcggc ctcccgctgg
    11221 gcgtcgcgcg cggcccggtc cgcggcctgc gggcgggcgt ccgcgcgggc ctgcggccgc
    11281 gcggcggcgg ccttgtcctg gtcctgggcc aggtacgccc agccggccgt gaaggtcgcc
    11341 aggcccaggg cggcggcgag ggccacccgg cgggtcctgc ggatcggacg gggcttgccg
    11401 gacggacggg agcgggctcg ggcgtgcttg ctcattcctc cgaccgtaca tcagcaggcc
    11461 ctcgcagccc gggtggctac gacgtgcgcg cctcgtcgga actcgggaag cgcacacgga
    11521 cggtgagacc gcccccggga gccggattgg cctcggcgct cagctccgcc ccgtgcgccc
    11581 gtgcgatcga ggccacgatc gacagcccca gtccggcgcc ctcacctgcg gtgtgctgcc
    11641 gttcggcgcg cctgcggaac ggctccagga gccccggcac gtccgccggg tcgatcaccg
    11701 ggccggtgtt cgacaccgtc agttcccctt gggtggaggt ggacacggcg atcctgccgc
    11761 cgtcgcggtt gtgacggacg gcattgatca gcaggttcct cagcaggtgc ccgagcaggg
    11821 tccggtcgcc cggcacggcc agcggcgcga gggtccgtac gacggtcagg ccctgctgcg
    11881 ggcaggccgc cagctcggcc gccgcgagcg ccgccaggtc caccggagcg gtggactcca
    11941 gcccctgctc cgaaacggcg agcagcagca gggactcgat gaggtgctcg ctggagtccg
    12001 cgaccccgat cagcctgtcc cggatccgcg cgaccttctc cggcgacggg tcccccgcca
    12061 ggccgatctc ggcggccgcc cgctgcacgg ccagcggggt gcgcagctcg tgcgccgcgt
    12121 tcgccgcgaa ccgccgctgc gccgagacga gctgctccat ccggcccagc atcgcgtcga
    12181 aggtgtcggc cagctgcttg agctcgccgg gcggggcgtc gagggagatc cgctcgtcca
    12241 ggttctcccc ggacaggcgg cgcgcggtct ccgtgatcac gccgaccggg cgcagcaccc
    12301 ggccggccat ccaccaggcg agccagatcg acagcacggc gaacacggcc agggcgagga
    12361 gggagtacat cagcagccgg tgccgggtgg cgtcggtgac ggcgtccgag aggttctggg
    12421 tgtaggcgta gctcttgagc tgctcgggcg tgggcgtctg gcccgggggc agcttccgcg
    12481 ccggttcgca gggacagtcc ggggcgaagg tccggccggg gaccggcccg ggcgactgga
    12541 ggacgtagcc cgggctgacg gtgcggacgg ccccgttgac gctcgcgtag aggccctggc
    12601 cgaccaggag gtagaccagc gcgaccaggc cgccgcccgc gaggagcagc agcgagccgt
    12661 acagggcggt gaggcggccg cgctcggtcc gcaacagccc cgtcgacggg ccggaccgtg
    12721 tgggacggag ccgcgtcccc cggcgcagcc gcatccgacg gagcctgatc cggcggagcc
    12781 gcaccctgct cggccgcacc ctgcccagcc gcatccggcg cccgctcacc gggccgcgat
    12841 ccggtagccc gcgcccggca cggtctcgat cagcggcggc tcgcccagct tggcgcggag
    12901 cttgctgagg gtgacgcgga cggcgttggt ggagtagctg gtgtcctgct cccacacctg
    12961 ctcgatcagg tcgtcgttgc tcacgacggc gccctcggcg cgcagcagcg cctccagcac
    13021 cgcgaactcc ttgcgggaca gcgcgagccg gtgcccgtcg cgggtggcgc tgcgccgggc
    13081 ggtgtcgacg gcgaccccgg cgcgctccag cacgggaggc agggcggggc gggcccgccg
    13141 gccgagggcc aggacgcggg cgagcagctc gtcgtaggcg aagggcttgg tgaggtagtc
    13201 gtcggcgccg aggccgaggc cctcgacgcg gtcccgtacg gtcccggacg cggtcagcat
    13261 caggacgcgg gtcagcagcc gctcgcgcac cacctgccgg cagacctcgt caccgtgcag
    13321 gccgggcagg tcgcggtcca ggacgaggac gtcgtactcg cccaggcgca gcagtcgcag
    13381 ggcctccggg ccgtcgctcg cctcgtcgac ggccagcgcg tcgcggcgca gcccctcggc
    13441 gatcatctcc cggaggaatt cctcgtcctc caccaccagt acgcgcatgg cgtcctcttt
    13501 acccgagatc ggcatttcgc cgttgtaagc agggtgcgag agggaagcga aaggcccttt
    13561 caccgcaggc tcgaggccat gaagcgatcc ctgatcatga ccacggccgc ggtcgtcacc
    13621 gggctgaccc tgttcgccac cgcctgcgcg aacgacgcgt ccgcggggaa gaaggactcc
    13681 tccggcggtt cgagcggcac cggcagcggc agcagcggcg gtgacggctc ggtggccgac
    13741 aacgccgtga agatgcgcca gtgcctgcgc gagcacggca tagacgtgcc cgaccccgag
    13801 cccggccagg acccgcgcgg gatgacgctg ggcggggacg ccgacccgca gaagatgcag
    13861 gaggccatga aggcctgcgg gatgagcacc ggcgccggca aggagcccac gcaggaggag
    13921 aaggacaagg agctggagtg gatccggtgc atgcgcgaga acggggtcgc cctcaaggac
    13981 cctgagtaca acggcggcat gaagagcgcc accgagatcc ccaagggcca ggagaaggcc
    14041 ttcgaggagg cccagaagaa gtgcgaaacc gcccgatgag gaagcggtcc aagtggctgc
    14101 tgggctcgct ggccgccgta ctggccgtct cgggcggcgg ctgggccgtc atcgatcggc
    14161 agcagggcga cacggacggg caggagcggc gcgcggccgg cgggctgccg ccggccacgg
    14221 caccggtcga gcgcggcgac ctcggctccg gcctccaggt ggagggcacc ctcggctacg
    14281 cgcaggagcg caagctgaac gcgggcgggc ccggggtgct gacgtgggtc gcgggcgagg
    14341 gctcggcggt ggagcgggac ggaaagctct acgaggtcaa cggcaggccg gtacggctca
    14401 tgtacgggtc cacgccgatg taccggccgc tgaaggccgg cgacaagggc gaggacgtca
    14461 aacagctcaa gcggaacctg caggccctcg gccacggcac cgggctcgac ccggaggacg
    14521 gggtcttcac cgcgggcacg gccacggcgg tcaagcggtg gcagaaggcg cacagggcgg
    14581 cggagacggg cgaggtcggc aaggaggaca tcgccttcgc ctcgggaccg cagcgggtcc
    14641 gcgggaacga cgcggcggtc ggtgacgagg tgggaccggg caaaccggtg ctgacggtga
    14701 cgggcaccga gcggatcgtc cgcttccaac tggagccggc caaggcgggc gcggtgaagt
    14761 ccggcgaccc ggtgaccatg cggctgccgg gaggcggcgg cgccaccggg aagatcgact
    14821 cggtgggcgg cgcggcgcag cccgacgaca agaacggcgg cggcgcggga ggccccggtg
    14881 gcggagacaa gaaggccgag gtcgaggtga tcgtgacctt cgacaggccc gccgaggtga
    14941 acgcgccgga ccagtccccg gtgaccgtcg gcctgaccgg cgagacccgc aagggcgtgc
    15001 tctccgtacc ggtcaacgca ctgctcgcgc tcgcgggcgg cggcttcggc gtccaggtcg
    15061 tgcaggacgg ccgggcccgc gaggtcccgg tcgagctggg catgttcggc aacggccggg
    15121 tcgaggtgac cggcgacgcc ctcaaggagg gcatgcaggt ggggatcccc aagctgtgac
    15181 ggacatgacg agagctcacc tgacgacgca tccgaccacg cttccggcga cgcacccggc
    15241 caccggtccg acggcgcgtc cggacacggt cgtggagctg accggggtca ccaaggagta
    15301 cccgggcggg gtcgcggccc tgcgcggggt cgacctgacc gtcaccgccg gggaactcct
    15361 cgccatcgtc ggcccgtcgg gatccggcaa gtccaccctg ctgcacatcg tcggcaccct
    15421 ggaccgcccg acggcgggcg gcgtacggat cgccgggtac gacatcgcgg ccctctcgga
    15481 ccgttcactg tcggccctgc gctcccggca cgtcggcttc gtcttccagt ccttccacct
    15541 cgtgcccggc atcagcgccc gcgcgaacgt cgccgagggg ctgctgtaca gcggcctctc
    15601 gcgggccgag cggctgcgcc gggccgcgga ggcgctggag cgggtgggcc tcggggaccg
    15661 gatggaccac cggccgcacg agctgtccgg cgggcagaaa cagcgcgtgg cgatcgcccg
    15721 cgccgtcgcg ggcgcaccgg acctgctgct ggccgacgag ccgacgggag cgctggacac
    15781 ggcgtccggg gaatcggtga tggagctgct gcgcgagctg aaccgggacg gggccaccat
    15841 cgcggtgatc acccacgacc aggagatcgc ggcgagcctg ccgcggcagg tgcggatccg
    15901 cgacggggag atcgtcgcgg accggagccc ggcgggggtg gcgtcatgag ccgcgcgagg
    15961 gctcgtacgc gcacgcaggt ccggcggttg acgccgccga ggctgtcccc gcgggacgtc
    16021 ctgcacgtcg gatcggcggg cctgcgcgcc cgcccgatgc gggtgttcct gtccgcgctc
    16081 ggcatcgcca tcggcatcgc gacgatgatc gcggtggtcg ggatctcctc ctccagccag
    16141 gccgagctgt tgcgggagct cgaccgactc ggcaccaaca tgctggtcgc gaagccgggc
    16201 gagggcatgt tcaccgggca ggacaccagg ctgcccaagg acgcgcccgg catgatctcc
    16261 cggatagcgg gggtcgagtc ggtcggcacc acgggcgacg tggccgagtc cgtacgccgg
    16321 tcggagaaca tcccgaaggg ggagacgggc ggcatcgtgc tcaaggcggc caaggacgac
    16381 ctactgggca ccctgcgcgc ccggatggcg agcggcacct ggctcaacgc cgccaccggc
    16441 cgctttccct cggtggtgct cggggacgtc tccgcgcgcc ggctcggcat caccgaaccg
    16501 ggccagcagg tcttcatcgg cggccggtac ttcacggtga tcggcatcct ggagcccgtc
    16561 ccgctggcac cggagatcga acgctccgca ctgatcggct gggacgcggc cgagcagctt
    16621 ctgggcttca acggtcaccc gacggcggtg tacgagcgct cggcggacga ccgggtggcg
    16681 gcggtccgca cgctgatccc ccggacggcc aacccgcaga ccccgagcgc ggtgcaggtc
    16741 agcgacccct cggcggcgct ccaggcgaag gccgccacgg agggcgcgtt cagcacgctg
    16801 ctgctgggcc tcggcgggat cgcgctgctg gtgggcgggg tcggcgtcgc caacaccatg
    16861 atcatctcgg tgctggagcg gcgccacgag atcggcctgc ggcggtccct gggtggcacc
    16921 aagggccaga tccggatcca gttcgtgacg gagtccctgc tgctgtccgg cctcggcggc
    16981 ctggcgggca tcgccctggg cggcgcggcc acggcggtct acgcccgcgc gggcgacctg
    17041 ccctgggtgg tcccgctctg ggcggtgacc ggcggcttcg cctcgaccct ggtgatcggc
    17101 actctggccg ggctctaccc ggcggtgcgc gcggcccggc tgtccccgac gctggccctg
    17161 gcggcggggt aggggacggg gtcgcgggac cggctccggg gggacgggcg ggcacagggc
    17221 ggcaaaaggc caggtgcaag cccgtccccc ggacccgatc accggcgtac attgaatcga
    17281 tgaggcgaac tccacgtcac gcggcgcgcg ttgtcatcct gtcccccacc ggatccgtgt
    17341 tcctcttccg cgaggacaac gtggaggtgg gcatccactg gctgccgccc ggcggcggca
    17401 tcgatcccgg cgagagcccc gaggactgcg tgcggcgcga gctccgcgag gagaccggct
    17461 ggaccgacct ggagcccgaa cggctgctct gcacctggga gcacgacttc acgtaccagg
    17521 gggtcccggt ccgccagcac gaacacatct acgtcaccac gggcccgcgc cgcgagccgg
    17581 tcctggaggc cccggacatc cactggcggt ggctctcccc gcagcgcctg gccgccctgg
    17641 gcgaaccggt gtggccgccg cgcctgccgg acctgctggc cgacatcccg gcgcagccgg
    17701 tccacctggg gctcctggcc taggtcgtct cttccggatc ttgtcgggcc cgcaagatcc
    17761 gaaagagacg acctagggct tcttcgcggt ggccttggcg tagagcgagg ccgcgtactc
    17821 cccgaggacc gtgctggtcg acacgtcgtc cgtgtccccg cccgtgagga tgccgatgat
    17881 cttcccgtcg cgggcgatcc acgcgctgcc gctggtgccg ccggggaagt cggcgcagtc
    17941 gaagcgctgc tgggtcgcgc tctcgcggac ggcgacggag gtgcaggtac ggggaacccc
    18001 gcggtcggcg gggtagccgg tcacggtcac ttcctcgccc gcacggccgc tggtgtcgag
    18061 cacggccgca ccggtcacgt cctcgacggt gcggcccttg tcgtccgggg cgaggcgggc
    18121 gaaggcgagg tcgtagtcgt cgtccgtccc ctcggcccag cggtcgtcct cgaagacctg
    18181 ctcgatcttc catgtgccgt acggggcgac cccgttggcg taggcggggg cgaagacggc
    18241 gctgccgccg ctctggtccc cctcgagcag acagtgccca gccgtgatga tcatgttccg
    18301 gccggggctg ctcaccacgg tggccgtgca gaagtggtca ctgttcaggc cgtcggtgaa
    18361 caaagccccg gtgaaggccg cgggcccacc gggcggcggc gtgacggccg gcggcagggt
    18421 gctgccgggc ggggcggaga gctggggctt cgccgcttgc gatcgcgacg acggccccgt
    18481 cggcgacgcg gtcggcgcgg ccttcgcccg cgcggacggc accgcttcgg gcggcggcac
    18541 cagcttcgcc acggcggcgg acgcccccag agccgcgacc gcacacagca ccgccgtcac
    18601 gacggtccgc ttgtccaccg gcatgatcat ccttccgctt caccctggcg aagcatgccc
    18661 cggcggcggg ggtgggtgca agaacgcgga cggctccggg ctcccccgtc acaccgtttc
    18721 gacctgcagg ttgcacacga atcgcaggcc ggggcggccg tccaggtcga cccctccgac
    18781 gggcacgaac ccggtgcggg ccagcaccgc gcgggagccc gcgttgtcga gcgtcgtgac
    18841 cgcccgcagc gcggtcagcc cgtactgcgt gaccgccagc ccgcacgcct tccgtaccgc
    18901 ggccgtggcc agtccccggc ccgtggcgcg ctcggcgatc cggtagccga gttcggccga
    18961 accgtcggcc acgtccacga ggttgacccg gcccaccact tccccggcgc cgtccacgag
    19021 cacgtggaag aagcacgccc cggtggcctg ctcggccatc agcgcggcgt gccgctcgtc
    19081 gaagtcggcg aaatagcggt cgccgcggtc gggcaccgcg gcggcgaagt aggcccggtt
    19141 ctcccgctcg aacgcgagca gggccggggc gtggtcgaag ctcagcggct ggagttcggg
    19201 catggctcga tgctaggccg tcgccccgcc gcccgcccct cgtagatctc ggcgtcaact
    19261 gcactgccag tgagcgcatt tgccgtattg atctatcatc gcttcgattt tcgccgcccg
    19321 tgccggcacg gggcgggcgc gaaccggttt cgacgagagg caacacgtac gtgcgactga
    19381 caggcaagca ccggatatcc ctggtcgccg tggcggccgc ggccgcgatc gtgggaagtc
    19441 tgcagctccc ctccagcgcg ttcggcaccg aggacaccgg gatcaccgtg ccgccggccg
    19501 cggagggtac cgattcccac gcggccgact ccgccgtcca cgggagcgac ggcactgcct
    19561 tcgaggacgg cgtcatgtcg ctcggtgcgg agccttcccg gaccgccgca cgggcggccg
    19621 cggcggccgc ggacgccgag cccgcacctc ctcagggcga ggggtggaag ctgagcggtg
    19681 cgaccaagtg gctgcagacc ggctacacga tcaagttcta cgaccagaag tccgcggact
    19741 ggctggcccc gtacgtgcag gcctccgccg ccgacctgcg gcgcatcacg aacctgccgg
    19801 tcaccgtcga cacgaagccg gtcggctggg actacgtacg gcccaggggc gaagtgatcg
    19861 tcggcgtcct gcaccgcccc tgcctgccgc ccgccgggga gggcagcatg ggcagcaccg
    19921 gctggaaggt ggtccgcgac gggtccggca gcgccaacct gagctgcggg ttcaccagct
    19981 cctcggtggc cgcgaccgtg accagcggcc acgcctacat cgacagcgag ttcttcacct
    20041 cggccggcaa gccgaccgcc gccatgggcg agacgtacat gcgcaaccac atcagccacg
    20101 agctcgggca cacgctgggc ctgacgcacg ccaaccgcag cctggagaag agcgactgcg
    20161 tcaaggggag cgactccggg cagttcccgg tcatgtgctc gcccgcgtac gcctaccagg
    20221 acaagcgcgc cggcacctac gtccagcagt tcgacgtcca gggcctgcgc cgcctcgcgg
    20281 ccggcgccgg agccgcgctc tccccgcagg gccgggtgac cggaatcggc gccaagtgcc
    20341 tggacgtcaa gggaggcaag gcggccaacg gcacgcagat ccagctctac acgtgcaacg
    20401 gctccgtcgc ccagtcgtgg atcctcggca aggacggcac cttccgcgcg ttcgggaagt
    20461 gcctggacaa cgcgcggaac gcgagcacca acggcaacag gatcagcctc cacgactgca
    20521 acggatcggc cgcacagcgc tggtccgtca acgccaaggg ccagatcgtc cacgtggcat
    20581 cgggcaaggt cctcgacgtg accggcggcg ccaccgccaa cggcacagcg
//
