LOCUS       NZ_BMVL01000004        26994 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence04, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000004
VERSION     NZ_BMVL01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 640938)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 557887
            Orig. end                         :: 584881
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26994
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26994
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26994
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16994](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16994
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(107..706)
                     /gene="idi"
                     /locus_tag="IE257_RS13500"
                     /old_locus_tag="GCM10010343_27810"
     CDS             complement(107..706)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766530.1"
                     /locus_tag="IE257_RS13500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27810"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_189968157.1"
                     /transl_table=11
                     /translation="MPTTPATAASSASNGTGTQEPIMLELVDESGNTIGTAEKLSAHQA
                     PGQLHRAFSVFLFDEQGRLLLQQRALGKYHSPGVWSNTCCGHPYPGESPFAAAARRTHE
                     ELGLSPSLLAQAGTVRYNHPDPSSGLVEQEFNHLFVGLAQAAVHPDPEEVEATAFVSAE
                     ELAKRHAEVPFSAWFMTVLDAARPAIRELTGDAAGW"
     gene            complement(861..2102)
                     /locus_tag="IE257_RS13505"
                     /old_locus_tag="GCM10010343_27820"
     CDS             complement(861..2102)
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267590.1"
                     /locus_tag="IE257_RS13505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27820"
                     /product="bifunctional class I SAM-dependent
                     methyltransferase/N-acetyltransferase"
                     /protein_id="WP_229920345.1"
                     /transl_table=11
                     /translation="MHHGLPRQAPGSDASTRHLLSLCGPLPERPRVLDLGCGPGRSALL
                     LAAEAGADGAVVTAVDLHAPFLDELRTAAAAGGLADRVRTVEADMGALTGEDFEDGSFD
                     LVWAEGSAYVLGFDAALARWKRLLAPGGTLVLTECQWSVPEPSAGARAFWDPHYALRTT
                     AGNLAAAQAAGYRVLGLHHLPDSDWAEYYGPLAERVRARSGAGSRAMAAALAATREELD
                     VRARHGHEYGYTGYVLRPVSAGDGEAWPARPETAADTAAVRAVNLAAFETPLEADLVDA
                     LRTDGAWLPGLSYVAEAPDGSVAAHALLTRCEVGGAPALALAPVATDPALQRSGAGSSV
                     VRALLAAARESGESLVLVLGHPEYYPRFGFVPASHFGIRAPFEVPDEAMMALVLDDSVP
                     VPAGTIAYPAPFGV"
     misc_feature    complement(2401..2415)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(2602..2745)
                     /locus_tag="IE257_RS38175"
     CDS             complement(2602..2745)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE257_RS38175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229920319.1"
                     /transl_table=11
                     /translation="MHVPDEGAVHDGHALVGGYAGQCGGGVLGTGRRADVEAEGAQLVS
                     ER"
     gene            2740..4356
                     /locus_tag="IE257_RS13510"
                     /old_locus_tag="GCM10010343_27830"
     CDS             2740..4356
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962486.1"
                     /locus_tag="IE257_RS13510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27830"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_229920320.1"
                     /transl_table=11
                     /translation="MHALRLALTDPRFDACAVTGALAVRAGAREALDKAAAVAVAEPGG
                     AGPYPDRLAAAVEAAGTTVQRPELGTLVAAVPAGPAERDAATAAVAAVDDEAVRLRTAV
                     KSRDGFFTTFCISPYSRYIARWCARRGLTPNQVTTASLITALIAAGCAATGERWGYVAA
                     GVLLLVSFVLDCTDGQLARYSLQYSTMGAWLDATFDRAKEYSFYAGLALGAARNGDDVW
                     ALAVGSMILMTCRHVVDFSFNEANHDATANTSPTAALSDRLDSVGWTVWLRRMIILPIG
                     ERWAMIAVLTAFTTPRIVFYALLVGCAFGALYTTAGRVLRSLTRRATRTDRAARALADL
                     ADSGPLAELQARLLRGRAGSFGSVYGAALGTLVMIAGAVFLPFGDPRLIAVAVIYVMTA
                     GLAVAAPLKGALDWLIPPLFRAAEYVTVLALAVKADVPGALPAAFGLIAAVAYHHYDTV
                     YRIRGGTGAPPHWLVRTIGGHEGRVLLITALAAVLVTREADFPVALTVMAVFVALVVLV
                     ESIRFWVSSGAPAVHDEGEPA"
     gene            4353..5105
                     /locus_tag="IE257_RS13515"
                     /old_locus_tag="GCM10010343_27840"
     CDS             4353..5105
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="IE257_RS13515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27840"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_189968161.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.8e-11, bitscore:
                     38.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPEGDEESLTVLDLTLG
                     NFAEVGLTEVAIVVGYRKEAVYARREALEAKYGVKITLIDNDKAEEWNNAYSLWCARDV
                     LKQGVILANGDTVHPVSVERTLLAARGNGQKIILALDTVKNLADEEMKVVTADGKGVQK
                     ITKLMDPADATGEYIGVTLIEPEAAEQLAEALKTTFERDPDLYYEDGYQQLVNDGFTID
                     VAPIGDVKWVEIDNHDDLAKGRTIACQY"
     gene            5093..6154
                     /locus_tag="IE257_RS13520"
                     /old_locus_tag="GCM10010343_27850"
     CDS             5093..6154
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="IE257_RS13520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27850"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_030385165.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.2e-20, bitscore: 68.7,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.6e-09, bitscore:
                     32.4, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDISRGAMDDLAGLLADQRISASGKLAIAISG
                     GSGVALRAKLEPVLPHADWYAVVDGTIDSAVKLADDIKGRRYDAVVGLGGGKIIDVAKY
                     AAARVGLPMVAVATNLSHDGICSPVSILDNDNGRGSYGVPTPIAMVIDLDVIKEAPVRF
                     IRAGIGDAISNISAIADWELSHKITGEPVDGLAAAMARTAGESVLRHPGGCGDDEFLTV
                     LSEALVLSGIAMSISGDSRPSSGACHEISHAFDLLHPGRSALHGEQVGIGAAFAMHLRG
                     AAEQSGLFVEVLRRHGLPVGPEEIGFSVDEFVAAVEYAPQTRPGRFTILEHLNLSAAEI
                     RDAYADYVKTIRS"
     gene            6132..6911
                     /locus_tag="IE257_RS13525"
                     /old_locus_tag="GCM10010343_27860"
     CDS             6132..6911
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="IE257_RS13525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27860"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_189968163.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRVSGEHWGGRLYMREISLRITRVLV
                     TTKVTPNQLTYLMTLAGVLALPALLVPGILGAVLGVVAVQMYLLLDCVDGEVARWKKQF
                     SLSGVYLDRVGAYLCDAAVLVGFGLRAADLWGPGGADWLWAFLGTLAALGAILIKAETD
                     LVGVARHQAGKPVVKDAAAEPRAKGMAFARRAAAALKFHRLILGIEASLLILVLAVVDQ
                     MQGDLYWSRVGVAVLAGIAMLQTVLHLVSILASSRLK"
     gene            6947..7792
                     /locus_tag="IE257_RS13530"
                     /old_locus_tag="GCM10010343_27870"
     CDS             6947..7792
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983096.1"
                     /locus_tag="IE257_RS13530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27870"
                     /product="glycosyltransferase"
                     /protein_id="WP_245384837.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-08, bitscore:
                     29.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNRPDELKALLDSVARQDGAPVEVVVVGQGVQVTGLPEGVRSID
                     LPENLGIPGGRNVGIEAFGPGGRDVDVLLFLDDDGLLERTDTAELCRQAFTEDPGLGII
                     SFRIADPDTGVTQRRHVPRLRASDPMRSSRVTTFLGGANAVRTTVFEQVGALPGEFFYA
                     HEETDLAWRALDAGWLIDYRADMVLLHPTTAPSRHAVYHRMVARNRVWLARRNLPAPLV
                     PVYLGVWLLLTLVRRPSVPALKAWFGGFREGWTTPCGPRRPMRWRTVWRLTRLGRPPVI
                     "
     gene            7887..8816
                     /locus_tag="IE257_RS13535"
                     /old_locus_tag="GCM10010343_27880"
     CDS             7887..8816
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972239.1"
                     /locus_tag="IE257_RS13535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27880"
                     /product="ABC transporter permease"
                     /protein_id="WP_189968167.1"
                     /transl_table=11
                     /translation="MSDTTHDGALATSRPPSDDAGLSPAELARKYGLSVSGARPRLGEY
                     VRQLWGRRHFIMAFSRAKLVAQYSQAKLGQVWQVATPLLNAAVYWLIFGLILGAGREMP
                     KGVYVPFLMMGIFVFTFTQSSVMAGVRAISGNLGLVRALHFPRASLPVSFSLQQLQQLL
                     YSMIVVFVIAIAFGNYPRLAWLLVIPTLALQFVFNTGLAMIFARMGSKTPDLAQLMPFV
                     MRTWMYASGVMFPIGIYLEDQPQWISDVLLWNPVAIYMDLIRFALIDDYGSSNLPPHVW
                     AFAVGWAVVIGIGGFVYFWKSEERYGRG"
     gene            8809..9591
                     /locus_tag="IE257_RS13540"
                     /old_locus_tag="GCM10010343_27890"
     CDS             8809..9591
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962489.1"
                     /locus_tag="IE257_RS13540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27890"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_189968169.1"
                     /transl_table=11
                     /translation="MADNNRGRVPTVIADGVHIVYRVNTGSAGKGAATAALSKIMRRKK
                     GDAPGVRRVHAVRGVSFTAYRGEAIGLIGSNGSGKSTLLRAIAGLLPCEEGKVYTDGQP
                     SLLGVNAALMNDLTGERNIVLGGLAMGMSREQIKQRYQSIVDFSGINEKGDFISLPMRT
                     YSSGMAARLRFSIAAAKDHDVLMIDEALATGDRSFQVRSEDRIRELRQKAGTVFLVSHN
                     NKSIRDTCDRVLWLEKGELLMDGPTEEVVSAYEKATNG"
     misc_feature    complement(9984..9998)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     misc_feature    complement(9986..9999)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            10001..10885
                     /gene="hpnC"
                     /locus_tag="IE257_RS13545"
                     /old_locus_tag="GCM10010343_27900"
     CDS             10001..10885
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742782.1"
                     /locus_tag="IE257_RS13545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27900"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_229920321.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.3e-36, bitscore:
                     120.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.2e-37,
                     bitscore: 122.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNATLDKATAENFPVAPVFLPRAWRDGLTAVYGYARLVDDIGDGD
                     LAPGGRDAVLLGLDPAAVDDRLAMLDALEADLMRVFGADSGPPRHPLLLALRPVVRAHG
                     LTPEPFLGLIEANRQDQHVARYGTYADLVGYCELSANPVGRLVLSLTGTSTPERIRRSD
                     AVCTALQIVEHIQDVAEDLGRDRIYLPAEDMRRFHVAEAELAAPTAGASVRALIAFESD
                     RARELLNEGTPLVGSVHGRLRLLLAGFVGGGRAALRAVTAAGFDVLPGPPKPTKSGLLR
                     EVAAVLRTAPRKG"
     gene            10882..11844
                     /gene="hpnD"
                     /locus_tag="IE257_RS13550"
                     /old_locus_tag="GCM10010343_27910"
     CDS             10882..11844
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890660.1"
                     /locus_tag="IE257_RS13550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27910"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_189968173.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.4e-57, bitscore:
                     190.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.6e-70,
                     bitscore: 231.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPTVEGPTHVSAPVQAAYSYCEAVTGSQARNFAYGIRLLPNDKR
                     QAMSALYAFSRRVDDIGDGTLAPEAKFARLEETRAVLGRIRAEEIDEDDTDPVAVALAH
                     AARRFPIPLGGLDELIDGVLMDVRGETYETWDDLRTYCRCVAGAIGRLSLGVFGTVNGS
                     ALGASDSARAAEYADTLGLALQLTNILRDVREDAANGRTYLPAEDLAKFGCSEGFRSDR
                     MPAGADFAGLVHHEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIEREPE
                     AVLRGRVSLPPHEKAYVAVRGLSGLDARTVSRQNTRRRG"
     gene            11844..12089
                     /locus_tag="IE257_RS13555"
                     /old_locus_tag="GCM10010343_27920"
     CDS             11844..12089
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE257_RS13555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010343_27920"
                     /product="hypothetical protein"
                     /protein_id="WP_189968175.1"
                     /transl_table=11
                     /translation="MTAITRLPAAAAGPAAARTHLRLRPVGRPGRDGARATTSAAGASL
                     PADCDHEGRAAVRPAARPTDDRPSGPEGHRSTGEHA"
     gene            12086..13465
                     /gene="hpnE"
                     /locus_tag="IE257_RS13560"
                     /old_locus_tag="GCM10010343_27930"
     CDS             12086..13465
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848333.1"
                     /locus_tag="IE257_RS13560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27930"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_189968177.1"
                     /sec_met_domain="DAO (E-value: 2.2e-08, bitscore: 29.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGIEQHAVVVGGGLAGVTTALELADAGMRVTLMEGRPRLGGLAF
                     SFKRGDLDVDNGQHVYLRCCTAYRWFLDRVDGAALAPLQDRLDVPVLDVAHPGGPRLGR
                     LRRSGLPVPLHLAGSLARYPHLSIAERLSVGRAALALRRLDPTDPALDGLDFATWLGRY
                     GQSARTIEALWDLVGIATLNATAEQSSLGLAAMVFKTGLLSENGAADIGWARVPLGELH
                     DTLTRKALDAAGVRTELRTRVTGISRMPEGAWRIDTEEECLEAGSVVLAVPQREAHALL
                     PAGALPDPDKLLDIGTAPILNVHVVYDRKVLKQPFFAALGSPVQWVFDRTESSGLPDGG
                     QYLALSQSVAQDDIDEPVSVLRAKYLPELERLLPAARGAKVRDFFVTRERTATFAPTPG
                     VGRLRPGARTDTPGLYLAGAWTATGWPATMESAVRSGLSAAHAALAALGRHREHPLQEA
                     A"
     gene            13462..14637
                     /locus_tag="IE257_RS13565"
                     /old_locus_tag="GCM10010343_27940"
     CDS             13462..14637
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="IE257_RS13565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27940"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_189968180.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.6e-58, bitscore:
                     192.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTISSTGTTSTTSTARTGTRGEPVNPGNPAVENTDASVGTAGG
                     GVEKADTIALLERGRTLSTPALRAAVDRLAAPMDTVAAYHFGWIDAQGNVADGDGGKAV
                     RPALALLSAEAAGAAAEVGIPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPA
                     LAILVGDALFALANEVLLELGTVEAGRATRRLTTASRKLIDGQAQDISYEHRERVSVEE
                     CLEMEGNKTGALLACAVSIGAVLGGADDRTADKLEEYGYHLGLAFQAVDDLLGIWGDPE
                     ATGKQTWSDLRQRKKSLPVVAALAAGGEASEQLAELLAADAKSSDFENFSEEEFAARAA
                     LIEAAGGRQWTADEARRQHAVAIRALDDVDMPQRVRDQLVALADFVVVRKR"
     gene            14757..16994
                     /gene="shc"
                     /locus_tag="IE257_RS13570"
                     /old_locus_tag="GCM10010343_27950"
     CDS             14757..16994
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042791.1"
                     /locus_tag="IE257_RS13570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27950"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_229920322.1"
                     /sec_met_domain="T2TS (E-value: 1.9e-148, bitscore: 490.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSAEGAGAGSETTPGAPPPGPPGRSAGLAAGPPAPAPPP
                     AAPARSGMGGPRGEYGPPGGPTGLLGRPLRRGAGPATGRTAAPAPSGAGRDTTRTTGRA
                     SADLRRPPDGVRPGAYEAAARATRNLLERQDPEGWWKGDLETNVTMDAEDLLLRQFLGI
                     RDEATTRAAALFIRGEQREDGTWATFHGGPPELSATVEAYVALRLAGDAPDAPHMSRAS
                     AWIRAHGGIAAARVFTRIWLALFGWWNWDHLPELPPELVFLPPWVPLNIYDFGCWARQT
                     IVPLTVVSALRPVRPAPFALDELHADARVPNPVGRLAPLTSWDGAFQRMDKALHIYRRF
                     APRRLRKAAMAGAGRWIIERQENDGCWGGIQPPAVYSVIALHLLGYDLRHPVMRAGLES
                     LDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGLRPDHPALVKAADWMLGEEIVRT
                     GDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIKHPDPARVEAAIARGVSWN
                     LGMQSRNGAWGAFDADNTSPFPNKLPFCDFGEVIDPPSADVTAHVVEMLAFEGRAGDAR
                     TRRGIAWLLAEQEPSGGWFGRWGTNYVYGTGSVVPALVAAGIAPGHPAIRRAVRWLESV
                     QNEDGGWGEDQRSYKDPSWAGKGASTASQTAWALMALLSAGEREGKAVERGIAHLVETQ
                     REDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGEPFAPAGEA"
     gene            16994..17668
                     /locus_tag="IE257_RS13575"
                     /old_locus_tag="GCM10010343_27960"
     CDS             16994..17668
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981496.1"
                     /locus_tag="IE257_RS13575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27960"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_189968182.1"
                     /transl_table=11
                     /translation="MSAAGGDRAPGPDPLLVACALRIEQAALRSAGGGSGRGSGRGAAG
                     HTLLRTGMGPSAAERAVGRALDRPEMDRAAVLATGFCAGLVPGMHPGDLVVAEQTRDPQ
                     GTVTCTGSALLAEALARAAPGRTVHTGALTGSDHVVRGQERAQLRATGAIAVDMESAAT
                     LWAATRGGGRPVAAVRVIVDAPEHELVRIGTVRGGISAFRVLRAVLPAFYEWHRSLLLP
                     RR"
     gene            17674..18705
                     /gene="hpnH"
                     /locus_tag="IE257_RS13580"
                     /old_locus_tag="GCM10010343_27970"
     CDS             17674..18705
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267606.1"
                     /locus_tag="IE257_RS13580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27970"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_189968184.1"
                     /sec_met_domain="PF04055 (E-value: 3.2e-18, bitscore: 61.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.6e-06, bitscore: 22.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.9e-09, bitscore: 31.3,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIRVGTYLLEQKLRKREKFPLIVELEPLYACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIHEIVRQLVARRKYVF
                     LCTNAMLLRKKIEKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLQVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FRKAFAGGNRRRWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELINDTDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETIASNRD
                     KSA"
     gene            18702..>19125
                     /locus_tag="IE257_RS38180"
     CDS             18702..>19125
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267607.1"
                     /locus_tag="IE257_RS38180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_373301817.1"
                     /sec_met_domain="Aminotran_3 (E-value: 7.7e-17, bitscore:
                     56.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARSPEEGGGRGKGFDLGALLAERGAERYELHAKHLNHQLPRML
                     HTIGFDKVYERAEGAHFWDAEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVLDAQLADL
                     TRFDCQPLPGLLAEKLLSYSPHLDRVFFGNSGTEAVE"
     assembly_gap    19126..19206
                     /estimated_length=81
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <19207..20118
                     /locus_tag="IE257_RS38185"
                     /old_locus_tag="GCM10010343_27980"
     CDS             <19207..20118
                     /NRPS_PKS="Domain: Aminotran_3 (1-205). E-value: 1.1e-54.
                     Score: 177.7. Matches aSDomain:
                     nrpspksdomains_IE257_RS38185_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="IE257_RS38185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27980"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_229920323.1"
                     /sec_met_domain="Aminotran_3 (E-value: 3.6e-56, bitscore:
                     185.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SLSVNGEGGFRDGFAPLLPDTRIALGDLAALERELKRGDVAAFVV
                     EPVQGKGVLTAPPGFLLAAQEMLHRRGALLIADEVQTGLGRTGDFYAYQHEPGVEPDLV
                     CVAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMED
                     EEVVANARAMGDLLRGRLAALVDEYELLHEVRGRGLMIGIEFGRPSSLGLRSRWTMLQA
                     ARKGLFAQMVVVPLLQKHRILTQVSGDHLEVIKLIPPLIVDERDVDRFVGAFREVMDEA
                     HGGSGLIWDFGRTLVKQAVAAR"
     aSDomain        19213..19824
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS38185_Aminotran_3.1"
                     /evalue="1.10E-54"
                     /label="IE257_RS38185_Aminotran_3.1"
                     /locus_tag="IE257_RS38185"
                     /protein_end="205"
                     /protein_start="1"
                     /score="177.7"
                     /tool="antismash"
                     /translation="LSVNGEGGFRDGFAPLLPDTRIALGDLAALERELKRGDVAAFVVE
                     PVQGKGVLTAPPGFLLAAQEMLHRRGALLIADEVQTGLGRTGDFYAYQHEPGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDE
                     EVVANARAMGDLLRGRLAALVDEYELLHEVRGRGLMIGIEF"
     gene            complement(20156..20947)
                     /locus_tag="IE257_RS13590"
                     /old_locus_tag="GCM10010343_27990"
     CDS             complement(20156..20947)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="IE257_RS13590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_27990"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_189968186.1"
                     /transl_table=11
                     /translation="MTQQIQEPELTGVRNFRDVGGLPTSGGRTVMTGRLFRSGHLAHAT
                     ESDAEFLASLGLHTIFDFRNGADHALEGPDVELPGVRNVNIPLSDPADGREFWRLVRDG
                     DLDQLRGILGDGKAAARMSNSYRGIIRQRTAEHGRVVHALAEDSVPALMHCAAGKDRAG
                     LSIAVTLLALGVEREAIVTDYLESNAPHRRYRVRRTDESAGARSPEVMELLAPLFDARA
                     EYLVAAFDTIDEIWGGVDRYLAEGLGLRPETLDRLRDRLLV"
     misc_feature    21041..21054
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    complement(21073..21088)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.03"
                     /tool="antismash"
     misc_feature    complement(21160..21176)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.64"
                     /tool="antismash"
     misc_feature    complement(21235..21249)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.71"
                     /tool="antismash"
     regulatory      21240..21436
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    21320..21335
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            21441..22391
                     /locus_tag="IE257_RS13595"
                     /old_locus_tag="GCM10010343_28000"
     CDS             21441..22391
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267610.1"
                     /locus_tag="IE257_RS13595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_28000"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_189968187.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKSLSLSRGFAVAGTGGAALALPLIGAAGAHAAGAP
                     AAAPAVAPAVAPQVPVAPQTAPVAAVQAAPAVYTVVPGDYLSKIAAERHLSGGWEQLYA
                     DNREAVGSNPSLIHPGLKLHLGGPGEAAAAPAAPEADAKPARQAAPKSERKQAGKAAPV
                     QREAAAEAPAEAPAAPQSAAGFVAPVSGGISTQYKVAGSMWSSGYHTGVDFIASSGTSV
                     KAVGAGTVVSAGWSGSYGNEVVIRHADGKYSQYAHLSQLSVSSGQSVTAGQSIGLSGST
                     GNSTGPHLHFEIRTSPSYGSDLDPIAYLRSKGASL"
     misc_feature    complement(22411..22425)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            22555..23340
                     /locus_tag="IE257_RS13600"
                     /old_locus_tag="GCM10010343_28010"
     CDS             22555..23340
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742770.1"
                     /locus_tag="IE257_RS13600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_28010"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_189968189.1"
                     /transl_table=11
                     /translation="MAATTTKLKTIGSYAAIGDSFTEGVGDPGPGDSYLGWADRLAVLL
                     ADQREEHDFRYANLAVRGKLLDQIVGDQLPRAKALAPDLVTFCAGGNDIIRPGTDPDDV
                     AERFEAAVADLTGAVGQVMITTGFDTRGVPVLKHLRGKVATYSAHVRAIADRYDCPVLD
                     LWSLKSVQDRRAWDTDRLHLSPEGHTRVALRAAQVLGLEVPADPDQPWPPQRPRGSVDV
                     TRDNIQWARDHLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     gene            23440..24681
                     /locus_tag="IE257_RS13605"
                     /old_locus_tag="GCM10010343_28020"
     CDS             23440..24681
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129487.1"
                     /locus_tag="IE257_RS13605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_28020"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_189968192.1"
                     /transl_table=11
                     /translation="MTGSRPLRPRLRALRPKAFGADPSGARLERIRRSPNFADGVFQNP
                     VGARNRPSGSMTEFAKIYFQREQRVRRSPAAPIPVHPTTLADLAKPPATGLRLTWMGHS
                     SVLAEIDGRRVLFDPVWGERCSPFPFAGPKRLHPVPVPLAALGPVDVVVISHDHYDHLD
                     LPTIKELAGTDTIFAVPLGVGAHLERWGVPADRLHELDWNESTEIAGLSLTATPARHFC
                     GRGLRNQQHTLWASWVVAGDEHRIYHSGDTGYFPGFKEIGAEHGPFDATMIQIGAYSEY
                     WPDIHMTPEEGMRAHLDLQGGTPQGTMLPIHWGTFNLALHPWDEPGEGTLTAAEGAGAA
                     VALPIPGQPFEPGASGAPHTPWWRPFVAGAATGGRIDGPSSVPPLGAGAVAGTAARVGS
                     AAAGGQEKPESVGS"
     misc_feature    complement(24865..24879)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            24976..26748
                     /locus_tag="IE257_RS13610"
                     /old_locus_tag="GCM10010343_28040"
     CDS             24976..26748
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037651.1"
                     /locus_tag="IE257_RS13610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_28040"
                     /product="ATP-binding protein"
                     /protein_id="WP_189968194.1"
                     /transl_table=11
                     /translation="MSGLRAARHATSRLAVTGPGRQIRPQLVRAAVLPTLAAGLSGAAA
                     VIFTLQLGGGAGERDARLWPVLTGCALLVIGALAAALLGAQRAAKAVRDRCEALRRSSV
                     RGRHELRTAADRLDRGETPARPVRGGPSSPAPGGDPAGLDEFWLLSQELRSAREQAHTT
                     LLRLAGPATPSDSERKVEVFVNLARRLQSLVHREISLLDELEDTVEDPDLLKELFHVDH
                     LATRIRRHAENLAVLGGAASRRQWTRPIDLSEVLRSSVAEVEQYTRVKVVPPAGGSVRG
                     HAVADVVHLLAELVENATVFSAPDTDVVLRAERVTAGIAVEVEDRGLGMPAEEQHRMNS
                     LLGDPDQVSVRSLLADGRIGLFVVSALARRHGIAVELKSNIYGGVLAVLVLPQELLGAE
                     VPSAADAAGGSRATSWGTGQGAAAAPLEPVRMDLPGPGPRPARAPVPVPVIVAEPASPP
                     APRPGTTVGPVPSPRTGADPAFGPPSDPPPGAGAMAWSAPATAPRGGPVPGPATGAVAW
                     SAPEPSAPSAPGGPDTGDRPLLPRRRAQEHLAPQLREAPAPRRAADSEQPVHDPGLMAA
                     FQRGFGLAQSENQA"
ORIGIN
        1 cccgctcgcc gccccgccga ccgcaggctg agcggcggtc ggcggtcggc ggtcggtcga
       61 cgaggcggca gggccgcgca gcgggacggc gcccggggcg tacgggctac cagcccgccg
      121 cgtcgccggt cagctcgcgg atcgcgggcc gcgctgcgtc cagtacggtc atgaaccagg
      181 ccgagaacgg tacttcggcg tgccgcttgg ccagctcctc ggcggagacg aaggcggtgg
      241 cctcgacctc ctccggatcc gggtgcacgg cagcctgcgc gagtcccacg aacaggtgat
      301 tgaactcctg ctccacgaga cccgatgagg ggtccgggtg gttgtagcgc accgttcccg
      361 cctgcgcgag cagcgagggc gacagcccca gctcctcgtg ggtccgccgg gccgcggccg
      421 cgaacggcga ctcccccgga taggggtgac cgcaacaggt gttcgaccag acgccggggg
      481 agtggtactt cccgagggcc cgctgctgga gcagcagacg gccctgctcg tcgaagagga
      541 acacggagaa cgcccggtgc agctggccgg gcgcctgatg ggcggagagc ttctccgccg
      601 tgccgatggt gttgccggac tcgtcgacca gttcgagcat gatcggttct tgagtaccgg
      661 tgccgttgga cgcgctgctc gcggcggtgg ctggtgtggt cggcataccc atccttcgct
      721 tcggacttcg gccttcagtc tgccgtacaa aagcggcttg tccccacttc ggagatccac
      781 gcatgttcgc cccccgtcgc gtgctaggcg acggggggcg gatcacatcg tgtgcggcat
      841 cacctgacgc cgcgcaggcg tcagaccccg aacggggccg ggtacgcgat cgtgcccgcc
      901 ggcaccggaa cggaatcgtc cagcaccagc gccatcatcg cctcgtccgg tacctcgaag
      961 ggcgcccgga tcccgaagtg cgacgccggt acgaaaccga agcgcgggta gtactccggg
     1021 tgccccagga ccaggaccag cgactccccg ctctcccgtg ccgccgccag cagggcccgt
     1081 acgaccgagc tgcccgcgcc cgagcgctgc agcgccgggt ccgtcgccac cggggcgagg
     1141 gcgagcgccg gggcgccgcc gacctcgcac cgggtcagca gggcgtgcgc cgcgaccgac
     1201 ccgtccggag cctcggccac gtacgacagc ccgggcagcc aggcgccgtc cgtgcgcagc
     1261 gcgtccacga ggtccgcctc cagcggggtc tcgaacgccg ccaggttgac cgcccgtacc
     1321 gcggccgtgt cggccgcggt ctccgggcgg gcgggccagg cctcgccgtc cccggcgctc
     1381 accgggcgca gcacgtatcc cgtgtacccg tactcgtgcc cgtgacgggc ccgtacgtcg
     1441 agctcctcgc gggtcgcggc cagcgccgcg gccatcgcgc ggctcccggc cccggaccgg
     1501 gcgcggaccc gctcggcgag cgggccgtag tactcggccc agtcggagtc gggcaggtgg
     1561 tgcaggccga gcacccggta ccccgccgcc tgggcggccg cgaggttgcc ggcggtggtg
     1621 cgcagcgcgt agtgcgggtc ccagaaggcg cgggcgccgg cggacggctc gggcaccgac
     1681 cactggcact cggtcaggac gagggtgccg cccggggcga gcagccgctt ccaccgcgcg
     1741 agcgcggcgt cgaagccgag gacgtaggcg gagccctccg cccagacgag gtcgaaggaa
     1801 ccgtcctcga agtcctcgcc ggtgagtgcg cccatgtccg cctcgacggt acggacgcgg
     1861 tcggcgagac caccggccgc ggcggccgtc cggagctcgt cgaggaaggg ggcgtgcagg
     1921 tcgacggcgg tcaccacggc cccgtccgcg cccgcctcgg cggcgagcag cagggcgctg
     1981 cggcccggac cgcagcccag gtcgaggacg cgcggccgct cgggcagcgg tccgcacagg
     2041 gacagcaggt ggcgggtgct cgcgtcggag cccggagcct gccggggcag gccgtggtgc
     2101 agggcgaaga aggcgtgcgt gaaatcgtcg acgccgcccg aatcctcgca ggagtcgtcg
     2161 aagcggtcgt cggaagtagt gctgtcggtc aacgtgaacc cttggaacgg gggctccggc
     2221 cgacgcggcc cagctgtggg gtcaggaccg gccggatgcc cgggaggagg gggagatgca
     2281 ccggagttcg ctgcgcatgg ccgcgaccac tacgacggtc atcaacccac ctctttccac
     2341 tcgacacgat caggggcgtg tccaccgtaa catccgggcc gtttgtggta ccgcgccgtg
     2401 atcgtcaatg atgatcggaa cccggcccgg agcccgaata ttcggcttat cggggcgtaa
     2461 acgggtggtg aacccctgct tccattcatc cgatagcctc tgccgacgtg ccgccgcccc
     2521 ctcaggcgcg cgttcggaat tcgttacaag gagtgagttc gtctgccgac cgtcatcctc
     2581 accggcctgc cggtccccgg atcaccgctc gctgacgagc tgcgctccct cggcttcgac
     2641 gtccgcccgg cggccggtcc ccaggacgcc gccgccgcac tggccggcgt acccgccgac
     2701 cagcgcgtgg ccgtcgtgga cagcgccttc gtcgggcacg tgcacgcact gcgcctcgcg
     2761 ctgaccgacc cgcgcttcga cgcctgcgcc gtcaccggcg ccctcgccgt ccgggccggc
     2821 gcccgcgaag ccctcgacaa ggccgccgcc gtcgccgtcg cggaacccgg cggcgccggc
     2881 ccgtacccgg accggctcgc cgccgcggtc gaggccgccg gaaccaccgt gcagcgcccc
     2941 gaactgggca cgctcgtcgc cgccgtcccc gccggcccgg cggagcggga cgcggcgacc
     3001 gccgccgtcg ccgccgtcga cgacgaagcc gtacgcctgc ggaccgcagt gaagtcccgc
     3061 gacggcttct tcaccacctt ctgcatcagc ccgtactcgc gctacatcgc ccgctggtgc
     3121 gcgcgccgcg gcctgacccc gaaccaggtc accaccgcct cgctgatcac cgcgctgatc
     3181 gcggccggct gcgcggccac cggcgaacgc tggggctacg tggcggccgg cgtgctgctc
     3241 ctcgtctcct tcgtactgga ctgcaccgac gggcagctcg cccgctactc gctccagtac
     3301 tcgacgatgg gcgcctggct cgacgccacc ttcgaccgcg cgaaggagta ctccttctac
     3361 gcgggcctcg cgctcggcgc ggccaggaac ggcgacgacg tatgggccct ggccgtcggc
     3421 tccatgatcc tcatgacctg ccggcatgtc gtggacttct ccttcaacga ggccaaccac
     3481 gacgccaccg ccaacacgag ccccacggcc gccctctccg accggctcga cagcgtcggc
     3541 tggaccgtgt ggctccgccg gatgatcatc cttccgatcg gtgagcgctg ggcgatgatc
     3601 gcggtcctga ccgccttcac caccccccgg atcgtcttct acgccctgct cgtcggctgc
     3661 gccttcggcg cgctctacac caccgccggg cgggtcctgc gctccctgac gcgccgggcc
     3721 acccgcaccg accgggcggc ccgggcactg gcagacctgg ccgactccgg cccgctcgcc
     3781 gagctccagg cccgcctgct gcgcggccgc gccgggtcct tcggctccgt gtacggggcg
     3841 gcgctcggca cgctggtgat gatcgcgggc gccgtgttcc tgccgttcgg cgacccgcgg
     3901 ctgatcgccg tcgcggtgat ctatgtcatg acggccggcc tcgccgtcgc cgcgcccctc
     3961 aagggcgccc tggactggct gatcccgccg ctgttccggg ccgccgagta cgtcacggtc
     4021 ctcgcgctcg ccgtgaaggc ggacgtcccc ggggccctcc cggcggcatt cggcctgatc
     4081 gcggcggtcg cctaccatca ctacgacacg gtgtaccgca ttcgcggtgg caccggcgcg
     4141 cccccgcact ggctggtgcg gacgatcggc ggccacgaag gccgggtcct gctgatcacg
     4201 gccctggcgg ccgtcctcgt aacgcgcgaa gcggacttcc ccgtcgcgct cacggtcatg
     4261 gccgtgttcg tggcactcgt ggtgctcgtg gagagcatcc gattctgggt ctcctccgga
     4321 gcacccgccg tacatgacga aggagaacca gcatgatcgg ccttgtactc gctgccggtg
     4381 ccggacgccg tctgcgtccc tacaccgaca ccctgcccaa ggcgctcgtg ccggtcggcc
     4441 ccgagggtga cgaggagagc ctgacggtcc tcgacctgac gctgggcaac ttcgccgagg
     4501 tcggcctcac cgaggtcgcc atcgtcgtcg gttaccgcaa ggaagccgtg tacgcccgcc
     4561 gcgaggccct ggaggccaag tacggcgtca agatcacgct gatcgacaac gacaaggccg
     4621 aggagtggaa caacgcctac tccctgtggt gcgcgcgtga cgtcctcaag cagggcgtga
     4681 tcctcgccaa cggcgacacc gtccacccgg tctcggtcga gcgcaccctg ctcgccgccc
     4741 gcggcaacgg ccagaagatc atcctcgccc tcgacacggt caagaacctg gccgacgagg
     4801 agatgaaggt cgtcacggcc gatgggaagg gcgtccagaa gatcaccaag ctgatggacc
     4861 ccgccgacgc caccggcgag tacatcggtg tcaccctcat cgagcccgag gccgccgagc
     4921 agctggccga ggccctgaag accaccttcg agcgcgaccc cgacctctac tacgaggacg
     4981 gctaccagca gctcgtcaac gacggcttca ccatcgacgt ggcccccatc ggtgacgtca
     5041 agtgggtcga gatcgacaac cacgacgacc tcgccaaggg ccggacgatc gcatgccagt
     5101 actgacgagg ctcatcccct cgcccgtcgt cgtcgacatc agtcgcgggg cgatggacga
     5161 cctggccggc ctcctggccg accagcggat ctccgcctcc ggcaagctgg ccatcgcgat
     5221 cagtggaggc tccggcgtgg cgctgcgcgc caagctggag cccgttctgc cgcacgcgga
     5281 ctggtacgcg gtcgtcgacg gcaccatcga ctccgcggtc aagctcgccg acgacataaa
     5341 gggccgccgc tacgacgccg tcgtgggcct gggcggtggc aagatcatcg acgtggccaa
     5401 gtacgccgcg gcgcgggtcg ggctgcccat ggtggccgtc gccaccaacc tctcgcacga
     5461 cggcatctgc tcgcccgtgt ccatcctgga caacgacaac ggccgcggtt cctacggcgt
     5521 gcccacgccg atcgccatgg tgatcgacct cgacgtgatc aaggaagcgc cggtccggtt
     5581 catccgcgcc ggcatcggtg acgcgatctc caacatctcg gcgatcgccg actgggagct
     5641 ctcgcacaag atcaccggcg agcccgtcga cggcctggcc gccgccatgg cccgtaccgc
     5701 cggcgagtcc gtactgcgcc accccggcgg gtgcggcgac gacgagttcc tcaccgtgct
     5761 ctccgaggcg ctggtgctct ccggcatcgc catgtcgatc agcggggact cccgcccgtc
     5821 gtccggcgcc tgccacgaga tcagccacgc cttcgacctg ctccacccgg gacgctccgc
     5881 gctccacggc gagcaggtcg gcatcggcgc cgccttcgcg atgcacctgc gcggggccgc
     5941 cgagcagtcg ggcctcttcg tcgaggtact gcgccggcac ggcctgccgg tcgggcccga
     6001 ggagatcggc ttcagcgtcg acgagttcgt cgcggccgtc gagtacgccc cccagacccg
     6061 cccgggacgc ttcacgatcc tggagcacct caacctgtcc gccgccgaga tcagggacgc
     6121 ttacgccgac tatgtcaaga ccatccgtag ctgaactgag gccggtcgtc caccccgcgg
     6181 gcgtgaagga ccgggtcagc ggcgagcact ggggcgggcg cctctacatg cgcgagatct
     6241 ccctgcgcat cacccgcgtc ctggtcacca ccaaggtcac gccgaaccag ctgacctacc
     6301 tgatgaccct cgccggcgtc ctggccctcc cggccctgct ggtgccgggc atcctgggcg
     6361 ccgtcctcgg cgtggtcgcg gtccagatgt acctgctgct cgactgcgtc gacggcgagg
     6421 tcgcccgctg gaagaagcag ttctcgctct ccggggtcta cctggaccgg gtcggcgcct
     6481 acctgtgcga cgccgcggtc ctcgtgggct tcggcctgcg cgccgccgac ctgtggggcc
     6541 ccgggggcgc cgactggctg tgggccttcc tgggcaccct ggccgcactc ggcgccatcc
     6601 tgatcaaggc cgagaccgac ctggtcggcg tcgcccgcca ccaggccggc aagcccgtgg
     6661 tcaaggacgc ggccgccgag ccgcgcgcga agggcatggc cttcgcccgc cgcgccgccg
     6721 ccgcgctcaa gttccaccgc ctgatcctgg gcatcgaggc ctcgctgctc atcctggtgc
     6781 tggccgtcgt ggaccagatg cagggcgacc tgtactggtc ccgcgtcggg gtcgccgtac
     6841 tggccggcat cgcgatgctc cagaccgtgc tgcacctggt gtccatcctc gcctccagca
     6901 ggctcaagtg agcgccccgc tgcggctggg cgccgtgatc atcaccatgg gcaaccggcc
     6961 cgacgagctc aaggcgctcc tcgactcggt ggcccgccag gacggcgccc ccgtcgaggt
     7021 ggtcgtcgtg ggccagggcg tgcaggtcac cggcctgccc gagggcgtcc gcagcatcga
     7081 cctgcccgag aacctgggca tcccgggcgg gcgcaacgtc ggcatcgagg ccttcggccc
     7141 cggcggccgc gacgtggacg tgctgctctt cctggacgac gacggtctgc tggagcgcac
     7201 cgacaccgcc gagctgtgcc ggcaggcctt caccgaggac cccgggctgg ggatcatcag
     7261 cttccggatc gccgatcccg acaccggtgt gacccagcgc cggcacgtgc cgcgcctgcg
     7321 cgcctccgac ccgatgcgct cctcccgggt gaccaccttc ctgggcggcg ccaacgccgt
     7381 ccgcaccacg gtgttcgagc aggtcggggc cttgccgggg gagttcttct acgcgcacga
     7441 ggagaccgat ctggcctggc gggcactcga cgcagggtgg ctgatcgact accgggcgga
     7501 catggtgctg ctgcacccga ccactgcccc ctcccggcac gcggtctacc accgtatggt
     7561 ggctcgtaac cgggtgtggc tcgcccgccg caacctgccc gccccgctgg tcccggtcta
     7621 cctgggcgtc tggctcctgc tgacgctcgt acgcaggccg tcggtgcccg cgctgaaggc
     7681 ctggttcggc ggtttccggg agggatggac cactccctgc ggaccccgcc gcccgatgag
     7741 gtggcgtacg gtctggcggt tgacccggct gggccgacct cctgtcatct gaccagcccg
     7801 cgtctgggaa catgacgcga tcacgggcct cgagccacca gcctgatgcc cacctggccg
     7861 catcttgaag acgaaagttt caacttgtga gtgacacaac ccacgacggc gccctcgcca
     7921 cgagcaggcc gccgtccgac gacgcggggc tgagccccgc ggagctcgcc aggaagtacg
     7981 gactctcggt cagcggcgcc cggccccgcc tgggcgagta cgtacggcag ctctggggcc
     8041 ggcgccactt catcatggcc ttctccaggg ccaagctggt cgcgcagtac agccaggcga
     8101 agctcggcca ggtctggcag gtggcgaccc cgctgctgaa cgcggccgtc tactggctga
     8161 tcttcggcct gatcctcggt gcgggccggg agatgcccaa gggcgtctac gtcccgttcc
     8221 tgatgatggg catcttcgtc ttcaccttca cccagagctc ggtgatggcg ggcgtccggg
     8281 cgatctccgg gaacctcggc ctggtgcgcg cgctgcactt cccgcgcgcc tcgctgccgg
     8341 tctccttctc gctccagcag ctccagcagc tgctgtactc gatgatcgtc gtcttcgtga
     8401 tcgccatcgc cttcggcaac tacccgcggc tcgcctggct gctggtcatc ccgaccctgg
     8461 cgctccagtt cgtcttcaac accggcctcg ccatgatctt cgcgcggatg ggttccaaga
     8521 cccccgacct ggcgcagctg atgcccttcg tgatgcgtac ctggatgtac gcctccggcg
     8581 tcatgttccc gatcgggatc tacctggagg accagccgca gtggatcagc gacgtgctgc
     8641 tgtggaaccc ggtcgcgatc tacatggacc tcatccggtt cgcgctgatc gacgactacg
     8701 gcagcagcaa cctgcctccc cacgtgtggg ccttcgcggt gggctgggcc gtggtgatcg
     8761 gcatcggcgg cttcgtgtac ttctggaagt ctgaggagcg ttacggccgt ggctgacaac
     8821 aaccgggggc gcgtccccac cgtgatcgcg gacggcgtcc acatcgtcta ccgggtcaac
     8881 accggcagcg cgggcaaggg cgcggccacc gccgcgctca gcaagataat gcgccggaag
     8941 aagggcgacg ccccgggcgt ccggcgggtc cacgccgtgc gcggggtctc cttcacggcc
     9001 taccgcggcg aagccatcgg cctcatcggc tccaacggct ccggcaagtc caccctgctg
     9061 cgcgccatcg cgggcctgct gccctgcgag gagggcaagg tctacaccga cggccagccc
     9121 tcgctgctgg gtgtcaacgc ggccctgatg aacgacctca ccggcgagcg gaacatcgtt
     9181 ctcggcggtc tcgcgatggg tatgagccgc gagcagatca agcagcgtta ccagagcatc
     9241 gtcgacttct cgggcatcaa cgagaagggc gacttcatct ccctgccgat gcgcacctat
     9301 tcctccggta tggcggcgcg cctgcgcttc tccatcgcgg cggccaagga ccacgacgtt
     9361 ctgatgatcg acgaggcact ggccaccggt gaccgcagct tccaggtgcg ttccgaggac
     9421 cggatccgcg aactgcggca gaaggccggc acggtcttcc tggtgagcca caacaacaag
     9481 tccatccgtg acacctgtga ccgggtgctg tggctggaga agggtgagct cctgatggac
     9541 gggcccaccg aggaagtcgt ctcggcatac gagaaggcca ccaacggctg acctccgggt
     9601 cgcgcggcgc cctcttccgg cgcttttccg cttcacccga aggcccccgc cgctcagcgc
     9661 ggcgggggcc tcaatcgtgc tctcgcattt cgcggcgaca ttcggtggcg gagcgaatac
     9721 ccgggagggc tccgcgacgt tctacagcgt aagctgaggc ggtcctcaat cacggcaaga
     9781 ggggacgatt ccccgcaggt gaagggctct ggggcagccc ggggaatccc cgggcggcgt
     9841 gtccgaaata ggatgtaatg ggtcggcagt gtagaacggg agatgtgacg gcaatggcta
     9901 cgggaattct ccggccccca ggcacaacgg ccgtccccgc cccgggcggc gggcggtgac
     9961 cccggggcac ggcatccggc ccctgtccga cacggtccac gtgaacgcca cactcgacaa
    10021 ggcgacggcg gagaacttcc ccgtcgcccc cgtcttcctg ccccgtgcct ggcgcgacgg
    10081 gctgacggcc gtctacgggt acgcccgcct cgtcgacgac atcggtgacg gcgacctcgc
    10141 ccccggcggc cgcgacgccg tcctcctcgg tctcgacccc gccgccgtcg acgaccggct
    10201 cgccatgctc gacgccctcg aggccgacct gatgcgcgtg ttcggcgccg actccggccc
    10261 gccccgccac ccgctgctgc tcgccctccg gcccgtcgtg cgcgcccacg gcctgacccc
    10321 cgagccgttc ctcgggctca tcgaggccaa ccgccaggac cagcacgtcg cgcgctacgg
    10381 gacgtacgcg gacctggtcg gctactgcga gttgtccgcg aacccggtcg gccgcctcgt
    10441 gctctccctc accggcacca gcacccccga acggatccgc cgctccgacg ccgtctgcac
    10501 ggccctgcag atcgtcgagc acatccagga cgtcgccgag gacctcggcc gcgaccgcat
    10561 ctacctgccc gccgaggaca tgcgccgctt ccacgtggcc gaggcggagc tcgcggcccc
    10621 gaccgccggc gcgtccgtac gcgccctgat cgcattcgaa agcgatcgcg cacgcgagct
    10681 gctgaatgaa ggcaccccgc tcgtgggtag cgtccacggc agactccggc tgctgctcgc
    10741 gggcttcgtg ggaggggggc gtgcggccct gcgagccgtc accgccgccg gtttcgacgt
    10801 cctccccggc ccgcccaagc ccaccaagag cggcctgctc cgcgaggtgg ccgccgtcct
    10861 gcgcacagcg ccgagaaagg ggtgagcccg accgtggagg gccccacaca cgtgtccgca
    10921 ccggtccagg ccgcctacag ctactgcgag gccgtcaccg gttcccaggc acgcaacttc
    10981 gcctacggca tccggctgct gccgaacgac aagcggcagg cgatgtccgc gctgtacgcc
    11041 ttctcgcggc gggtcgacga catcggtgac ggcacgctgg cccccgaggc caagttcgcc
    11101 cggctcgagg agacccgcgc cgtgctcggg cggatccggg ccgaggagat cgacgaggac
    11161 gacaccgacc cggtcgcggt cgccctcgcg catgccgcgc gccgcttccc catcccgctc
    11221 ggcggcctcg acgaactcat cgacggggtc ctgatggacg tccgcggcga gacctacgag
    11281 acctgggacg acctcaggac ctactgccgc tgcgtggccg gggccatcgg gcggctctcg
    11341 ctcggcgtgt tcggcacggt gaacggctcc gccctcgggg catccgactc cgcgcgcgcc
    11401 gcggagtacg ccgacaccct cggtctcgcc ctgcaactca ccaacatcct gcgggacgtt
    11461 cgcgaggacg cggccaacgg gcgtacctac ctgcccgccg aggacctcgc caagttcggc
    11521 tgctcggaag gcttccgcag cgaccggatg cccgccggcg ccgacttcgc cgggctcgtc
    11581 caccacgaag tccgccgtgc ccgggccctg ttcgccgagg gctaccggct gctgccgatg
    11641 ctcgaccggc gcagcggtgc ctgcgtggcc gccatggccg gcatctaccg gcggctgctg
    11701 gaccgtatcg agcgcgagcc cgaggcggtg ctgcggggcc gcgtgtcgct gccgccgcac
    11761 gagaaggcgt acgtcgcggt gcgcggcctg tccggcctcg atgcgcggac cgtctcccgc
    11821 cagaacacgc ggaggcgagg ctgatgaccg cgatcacccg gctcccggcg gccgcagccg
    11881 gtccggccgc ggcgcgcacg cacctgcgcc tgcgcccggt ggggcgtccc ggcagggacg
    11941 gcgcccgggc aaccacttcg gcggcgggcg cgtctcttcc ggcggactgc gaccacgagg
    12001 gccgggccgc cgtacgcccg gcggcccggc ccaccgacga ccgaccgtcc ggcccggagg
    12061 gccaccgcag cacgggggag cacgcatgac cggcatcgag cagcacgcgg tcgtcgtggg
    12121 cggcggactc gccggggtca ccaccgccct cgaactcgcc gacgcaggga tgcgcgtcac
    12181 cctgatggag ggccgccccc ggctcggcgg cctcgccttc tccttcaagc gcggcgacct
    12241 cgacgtcgac aacggccagc acgtctatct gcgctgctgc accgcctacc ggtggttcct
    12301 cgaccgcgtc gacggcgcgg ccctcgcccc cctgcaggac cggctcgacg tccccgtcct
    12361 ggacgtcgcc caccccggcg gcccgcgact gggccggctg cgccgcagcg gcctgcccgt
    12421 gcccctgcac ctggccggat cgctcgcccg ctacccgcac ctctccatcg ccgagcgact
    12481 gagcgtcggc cgcgccgccc tcgcgctgcg ccggctggac cccaccgacc cggcgctgga
    12541 cggcctggac ttcgcgacct ggctcggccg ctacggccag tcggcccgca cgatcgaggc
    12601 cctgtgggac ctggtcggca tcgccacgct caacgccacc gccgagcagt cctcgctggg
    12661 cctggccgcc atggtcttca agaccggcct gctctccgag aacggcgccg ccgacatcgg
    12721 ctgggcccgg gtcccgctgg gcgaactgca cgacaccctc acccgcaagg cgctcgacgc
    12781 ggccggcgta cggaccgaac tgcgcacccg cgtcaccggc atctcccgca tgcccgaagg
    12841 ggcgtggcgg atcgacaccg aggaagagtg cctggaggcg ggttccgtgg tcctcgccgt
    12901 cccgcagcgc gaggcccacg cactgctgcc cgccggcgcc ctccccgacc ccgacaagct
    12961 cctggacatc ggcaccgcgc ccatcctcaa cgtccacgtg gtctacgacc gcaaggtgct
    13021 caagcaaccc ttcttcgccg ccctcggctc cccggtgcag tgggtcttcg accgcaccga
    13081 gtcctccgga ctgcccgacg gcggccagta cctggcgctc tcccagtccg tcgcccagga
    13141 cgacatcgac gaacccgtct ccgtcctgcg cgccaagtac ctgcccgagc tggagcggct
    13201 gctgcccgcc gcgcgcggcg ccaaggtacg ggacttcttc gtcacccggg agcggacggc
    13261 caccttcgcc cccacccccg gcgtcggccg gctgcgcccc ggggcgcgga ccgacacgcc
    13321 ggggctctac ctcgccggtg cgtggactgc cacgggctgg cccgcgacca tggagagcgc
    13381 cgtccggagc ggactgagcg cggcgcacgc cgcactcgcc gcgctcggcc gccaccgcga
    13441 acaccctctg caggaggcgg catgacgagc accatcagta gcaccggcac caccagcacc
    13501 acgagcacag cacgtacagg aacaagagga gagccagtga acccggggaa tccggctgtc
    13561 gagaacacgg atgccagtgt gggcacagcc ggagggggcg tggagaaggc ggacacgatc
    13621 gctctcctgg aacgcggccg tacgctgtcg acccccgcgc tccgcgccgc cgtcgaccgg
    13681 ctcgcggcgc ccatggacac cgtcgccgcc taccacttcg gctggatcga cgcccagggc
    13741 aacgtggcgg acggcgacgg cggcaaggcc gttcgccccg cgctcgcact gctctccgcg
    13801 gaggccgcgg gcgcggcggc cgaggtcggc atccccggcg ccgtcgcggt cgagctcgta
    13861 cacaacttct cgctgctgca cgacgacctg atggacggcg acgagcagcg ccgccaccgc
    13921 gacacggtgt ggaaggtgca cggcccggcc ctcgcgatcc tcgtcggcga cgccctgttc
    13981 gccctcgcca acgaggtgct gctggagctc ggcaccgtgg aggccggccg tgcgacccgc
    14041 aggctgacca ccgccagccg caagctcatc gacggccagg cccaggacat ctcctacgag
    14101 caccgcgagc gcgtcagcgt cgaggaatgc ctggagatgg agggcaacaa gaccggcgcc
    14161 ctgctcgcct gcgcggtctc catcggcgcc gtcctcggcg gcgcggacga ccgtaccgcc
    14221 gacaagctgg aggagtacgg ctaccacctc gggctcgcct tccaggccgt cgacgacctg
    14281 ctcggcatct ggggcgaccc cgaggcgacc ggcaagcaga cctggagcga cctgcgccag
    14341 cgcaagaagt ccctgcccgt cgtcgccgcc ctcgcggccg gcggcgaggc gtccgagcag
    14401 ctcgccgaac tgctcgccgc cgacgccaag agcagcgact tcgagaactt ctcggaggag
    14461 gagttcgccg cccgcgcggc cctcatcgag gcggccggcg gccgccagtg gaccgccgac
    14521 gaggcacgcc gccagcacgc cgtcgcgatc cgggccctgg acgacgtcga catgccgcag
    14581 cgcgtgcgcg accagctcgt ggccctcgcg gacttcgtcg tcgtgcgcaa gaggtgatcg
    14641 ccacccgaca gcggatatga atcgcgagtc gccggccggc gccgccacct gagcgtggcg
    14701 cgcacggccg acggcagacc ccagcacagc acaggacact gttctaaggg gaagccatga
    14761 cagcgacgac cgacggcagc gccgagggcg ctggcgctgg cagcgaaacc accccgggcg
    14821 ctccgccgcc cggcccgccg ggccgcagcg ccggcctggc cgccgggccc ccggcaccgg
    14881 caccgccccc ggcggcgccg gcccggtccg gcatgggcgg accgcgcggc gagtacggac
    14941 caccgggcgg gccgaccggc ctgctggggc gcccgctgcg ccgcggggcg ggcccggcca
    15001 ccgggcgcac ggccgccccg gcgccctccg gagcgggccg cgacacgacc cggaccaccg
    15061 ggcgggcgag cgccgacctg cgccggcccc cggacggcgt ccggccgggg gcgtacgagg
    15121 ccgccgcgcg cgccaccagg aacctgctgg agcgccagga ccccgagggc tggtggaagg
    15181 gcgacctgga gaccaacgtc accatggacg cggaggacct gctgctgcgg cagttcctcg
    15241 gcatccggga cgaggccacc acccgcgccg ccgccctctt catccggggc gagcagcggg
    15301 aggacggcac ctgggccacc ttccacggcg gaccgcccga actgtccgcc accgtcgagg
    15361 cctacgtcgc gctgcgcctg gcaggggacg cgcccgacgc tccccacatg agccgcgcct
    15421 cggcctggat ccgcgcccac ggcgggatcg ccgccgcccg cgtcttcacc cggatctggc
    15481 tggccctctt cggctggtgg aactgggacc acctccccga actcccgccc gagctggtct
    15541 tcctgccgcc ctgggtgccc ctgaacatct acgacttcgg ctgctgggcc cgccagacca
    15601 tcgtgccgct caccgtggtc tccgcgctgc gcccggtccg cccggccccc ttcgccctgg
    15661 acgagctgca cgccgacgcc cgggtgccca atcccgtcgg cagactcgcc ccgctgacca
    15721 gctgggacgg cgccttccag cggatggaca aggccctgca catctaccgg cggttcgcgc
    15781 cgcgccgact gcgcaaggcg gcgatggccg gcgccggccg ctggatcatc gaacgccagg
    15841 agaacgacgg ctgctggggc gggatccagc cgcccgccgt gtactcggtc atcgccctgc
    15901 acctgctcgg ttacgacctg cggcatccgg tgatgcgcgc cggactggag tccctggacc
    15961 ggttcgcggt gtggcgcgag gacggcgccc ggatgatcga ggcctgccag tccccggtgt
    16021 gggacacctg cctcgccgcg atcgccctgg ccgacgcggg actgcgcccc gaccaccccg
    16081 cgctggtcaa ggccgccgac tggatgctcg gcgaggagat cgtccgcacc ggggactggg
    16141 cggtgcgccg gcccgggctc gcccccggcg gctgggcgtt cgagttccac aacgacacct
    16201 accccgacat cgacgacacc gccgaggtgg tcctcgccct gcgccggatc aagcaccccg
    16261 atccggcccg ggtcgaggcg gccatcgccc gcggggtgtc ctggaacctc ggcatgcagt
    16321 ccaggaacgg ggcgtggggc gccttcgacg ccgacaacac cagccccttc ccgaacaagc
    16381 tgcccttctg cgacttcggc gaggtcatcg acccgccctc ggccgacgtc accgcccacg
    16441 tggtggagat gctcgccttc gagggccggg cgggcgatgc gcggacccgg cgcggcatcg
    16501 cctggctgct cgccgaacag gagccgagcg gcggctggtt cggccgttgg ggcaccaact
    16561 acgtctacgg gacggggtcg gtggtcccgg ccctcgtcgc ggcgggcatc gccccggggc
    16621 accccgcgat ccggcgggcc gtgcgctggc tggagtccgt acagaacgag gacggtgggt
    16681 ggggcgagga ccagcgctcc tacaaggacc cgtcctgggc cgggaagggc gcctcgaccg
    16741 cctcgcagac cgcctgggcg ctgatggccc tgctgtccgc gggcgagcgc gagggcaagg
    16801 ccgtcgaacg cggcatcgcc cacctggtgg agacccagcg ggaggacggc acctgggacg
    16861 agccatactt caccgggacc ggattcccct gggacttctc catcaactac cacctgtacc
    16921 ggcaggtgtt cccgctcacc gcgctcggcc gctacctgta cggggaaccg ttcgccccgg
    16981 ccggggaggc gtgatgtccg ccgcgggcgg ggaccgggcc ccgggacccg acccgctgct
    17041 ggtggcctgc gcgctgcgca tcgagcaggc cgcgctgcgc agcgccggcg gcggatcggg
    17101 gcgcgggtcg ggccgcggag cggccgggca caccctgctg cgcaccggga tgggcccgag
    17161 cgcggccgag cgggccgtcg ggcgggcact ggaccggccg gagatggacc gggccgccgt
    17221 cctcgcgacc gggttctgcg ccgggctggt ccccggtatg caccccggtg acctggtcgt
    17281 cgccgagcag acccgggacc cgcagggaac cgtcacctgt accggcagcg cgctgctcgc
    17341 cgaggcactg gcccgggccg ccccgggccg gaccgtgcac accggcgcgc tgaccggatc
    17401 cgaccacgtc gtccgcggcc aggagcgcgc gcagctgcgc gccaccggcg ccatcgcggt
    17461 cgacatggag tccgcggcca ccctgtgggc cgccacccgg ggcggtggcc gcccggttgc
    17521 ggccgtccgg gtgatcgtgg acgctccgga gcacgagctc gtccgtatcg gcacggttcg
    17581 cgggggaata tcggccttcc gtgtcctgcg tgccgtactg cccgcgtttt atgaatggca
    17641 ccgttcgttg ctgctcccca ggaggtgagc cagatggcca tgccgctgcg ccagtccatc
    17701 agggtcggga cgtatcttct cgaacagaag ctccgcaagc gcgagaagtt cccgctgatc
    17761 gtcgaactgg aaccgctcta cgcctgcaac ctggcctgtg aggggtgcgg gaagatccag
    17821 cacccggccg gggtgctcaa gcagcgcatg ccggtcgcac aggcggtcgg cgccgtgctg
    17881 gagtccggtg cgcccatggt gtccatcgcg ggcggcgagc ccttgatgca cccgcagatc
    17941 cacgagatcg tccggcagtt ggtggcgcgc cggaagtacg tgttcctctg caccaacgcg
    18001 atgctgctgc gcaagaagat cgagaagttc accccttccc cgtacttcgc cttcgccgtg
    18061 cacatcgacg ggctgcgcga gcgccacgac gagtcggtgg ccaaggaagg cgtcttcgac
    18121 gaggcggtcg ccgccatcaa ggaggcgaag aggcgtggtt tccgggtgac caccaactcc
    18181 accttcttca acaccgacac cccgcagacg atcatcgagg tgctcaacta cctcaacgac
    18241 gacctccagg tcgacgaaat gatgatctcg cccgcctatg cctacgaaaa ggctcccgac
    18301 caggagcact tcctgggcgt cgagcagacc cgggaactct tcaggaaggc cttcgcgggt
    18361 ggcaaccggc ggcgctggcg gctcaaccac tccccgctct tcctggactt cctggaagga
    18421 aaggccgatt tcccctgcac ggcctgggcc attccgaatt actccctctt cgggtggcag
    18481 cgcccctgct atctgatgag cgacggctac gtgccgacgt accgcgagct catcaacgac
    18541 accgactggg acaagtacgg ccgcggaaag gacccgcgct gcgcgaactg catggcgcac
    18601 tgcggctacg agcccaccgc cgtcctcgcc accatgggct ccctcaagga gtccctgcgc
    18661 gcggcccggg agacgatcgc cagcaaccgg gacaagtcgg catgaccgcg cggtcaccgg
    18721 aggaaggggg cggccggggc aagggcttcg acctcggcgc cctgctggcc gagcgcggcg
    18781 ccgaacgcta cgagctgcat gccaagcacc tcaaccacca gctgccccgg atgctgcaca
    18841 ccatcggctt cgacaaggtc tacgagcggg ccgagggcgc ccacttctgg gacgccgagg
    18901 gcaacgacta cctggacatg ctggccgggt tcggggtgat gggcctgggc cggcaccacc
    18961 cggtcgtccg ccgcgccctg cacgacgtcc tggacgccca gctcgccgac ctcacccgtt
    19021 tcgactgcca gccgctgccc ggactgctgg ccgagaagct gctctcgtac agcccgcacc
    19081 tggaccgggt cttcttcggc aacagcggca ccgaggccgt ggagannnnn nnnnnnnnnn
    19141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19201 nnnnnntccc tctcggtgaa cggggagggc ggcttccgcg acggcttcgc gccgctgctc
    19261 cccgacacca ggatcgcgct gggtgacctc gccgcgctgg agcgggagct gaagcgcggg
    19321 gacgtggccg ccttcgtcgt cgagcccgtc cagggcaagg gggtgctgac cgcaccgccc
    19381 gggttcctgc tcgccgcgca agagatgctg caccggcggg gggcgctgct gatcgcggac
    19441 gaggtgcaga ccggcctcgg gcgcaccggc gacttctacg cctaccagca cgagccgggc
    19501 gtggagccgg acctggtgtg cgtggcgaag gcgctgtcgg gaggctacgt gccggtcggc
    19561 gccaccctgg gcaaggactg gatcttcaag aaggtctact cgtccatgga ccgggtcctc
    19621 gtgcactccg ccagcttcgg ctcgaacgcc caggcgatgg cggcgggcct ggcggtgctg
    19681 tccgtcatgg aggacgagga ggtcgtcgcc aacgcccggg ccatgggcga cctgctgcga
    19741 gggcggctcg ccgcgctggt ggacgagtac gagctgctgc acgaggtgcg ggggcgcggg
    19801 ctgatgatcg gcatcgagtt cggccggccg tcctcgctgg gcctgcgcag ccggtggacc
    19861 atgctgcagg cggcccgcaa gggactcttc gcacagatgg tcgtggtgcc gctgctccag
    19921 aagcaccgga tcctcaccca ggtctccggg gaccacctgg aggtgatcaa gctgatcccg
    19981 ccgctgatcg tggacgagcg ggacgtggac cggttcgtcg gcgccttccg cgaggtgatg
    20041 gacgaggcgc acggcgggtc cggactgatc tgggacttcg gcaggacgct ggtgaagcag
    20101 gccgtcgccg cgcgctgacg gcctgccgtc ccggcgggga accggtcccg ccgcgtcaga
    20161 ccaggagccg gtcgcgcagc cggtcgaggg tctcgggccg cagcccgagg ccctccgcca
    20221 ggtagcggtc caccccgccc cagatctcgt cgatggtgtc gaaagcggcc accaggtact
    20281 cggcgcgggc gtcgaagagc ggtgcgagga gctccatcac ctcgggggag cgggcgcccg
    20341 ccgactcgtc ggtgcggcgc acgcggtagc ggcggtgcgg ggcgttcgac tccaggtagt
    20401 ccgtcacgat cgcctcgcgc tcgacgccca gcgcgagcag ggtgacggcg atcgacaggc
    20461 cggcccggtc cttgccggcc gcgcagtgca tgagcgcggg gacgctgtcc tcggcgaggg
    20521 cgtgcacgac ccggccgtgc tcggcggtgc gctgccggat gatcccgcgg taggagttcg
    20581 acatccgggc cgccgccttg ccgtcgccca ggatcccgcg cagctggtcg aggtcgccgt
    20641 cgcggaccag ccgccagaac tcgcgcccgt cggccgggtc cgagagcggg atgttgacgt
    20701 tccggacgcc gggcagttcg acgtccggac cctccagggc gtggtcggcg ccgttgcgga
    20761 agtcgaagat ggtgtggagg ccgagcgagg ccaggaattc tgcatcgctt tcggtggcat
    20821 gtgcgagatg tccgcttcgg aacagtcgtc ccgtcatgac cgttcgtccg ccagaagtcg
    20881 gcaatccccc cacatcgcgg aaattgcgca ctccggtcag ctccggctcc tgtatctgct
    20941 gggtcaaagc aactcctccg ccgcgtcctg ggccctgtgt ccgaattaca ctacttggcg
    21001 ccaacttgcc atatccggag gcgagatcgg gcacgtcccc gtgagccaga tcatacggtg
    21061 accgtgagtg cctgatcgct gaaggcgaat ggccaagtcg gggcggctgt tggcggccgg
    21121 gaatggacag agggtgaccg gaattccgcc ggtccctcat gcctgttatt ccgtcaggga
    21181 attcgcggct tgtagcgcgc ggccgcaagg gattaccttc gcgatcgatc cgggcggaac
    21241 gccaaatcct gccgcctccc ggaaaccgca tccgacctat tcgtgcggca ggagcggggg
    21301 aaccaggtaa gccgccggcc cggcgatctt ttcaccggga cggctcgggg tgaagccgtt
    21361 catgtcccgt acatgtacgg ccggacatct ccagtccgaa cccgacagct cacctcgcag
    21421 gcgccggaga ggaattcgtc atgcctgcaa agggtaagca ccgccgtccc aagtcccttt
    21481 ccctttcgcg cggtttcgcc gtcgccggaa ccggtggcgc cgccctcgcg ctcccgctga
    21541 tcggcgccgc cggcgcccac gcggccggcg ctccggccgc cgctcccgcg gtggcccccg
    21601 cggtcgcccc gcaggttccg gtcgcgccgc agacggcgcc cgtcgccgcc gtgcaggccg
    21661 ctcctgccgt ctacaccgtg gtgccgggcg actacctctc caagatcgcc gcggagcgcc
    21721 acctgtccgg cggctgggag cagctgtacg ccgacaaccg cgaggccgtc ggcagcaacc
    21781 cgtcgctgat ccacccgggc ctgaagctgc acctcggcgg tccgggcgag gcggctgcgg
    21841 ccccggctgc tcccgaggcc gacgcgaagc cggcccggca ggccgcgccg aagtccgagc
    21901 gcaagcaggc cggtaaggcc gccccggtgc agcgggaagc cgccgccgag gctcctgccg
    21961 aggcccccgc cgcaccgcag tcggccgccg gcttcgtggc ccccgtcagt ggcgggatct
    22021 ccacccagta caaggtcgcg ggcagcatgt ggtcctccgg ctaccacacc ggcgtcgact
    22081 tcatcgccag ctccggcacc agcgtcaagg ccgtcggcgc gggcaccgtg gtctccgccg
    22141 gctggagcgg ctcgtacggc aacgaggtcg tcatccgcca cgcggacggc aagtactccc
    22201 agtacgccca cctctcccag ctctccgtct cctccggcca gagcgtcacc gccgggcaga
    22261 gcatcggcct ctccggctcc accggcaatt cgaccggtcc gcacctgcac ttcgagatcc
    22321 gcacgagccc gtcctacggc tcggacctgg acccgatcgc gtacctccgc tcgaagggcg
    22381 cgagcctctg acggcacccg ccgtcggatc atcgacgcgc gtgaggccgg gacccgaggg
    22441 gggtcccggc ctcacgtgta cttattcctt atcccgtgcg tggtatagat cacggtccgt
    22501 caacccctca ttacgttggc gtaggttggt tacgggagtg aagtatgggt tcccgtggca
    22561 gcgacgacga cgaaactcaa gaccatcggc tcgtacgcgg cgatcgggga cagcttcacc
    22621 gaaggcgtgg gggacccggg acccggggat tcttatctcg gctgggcgga ccggctcgcc
    22681 gtgctcctgg ccgatcagcg cgaagagcac gacttccggt atgcgaatct ggcggtgcgg
    22741 gggaagctcc tcgaccagat cgtaggcgac caactcccgc gggccaaggc cctcgcgccg
    22801 gacctcgtga ccttctgcgc gggcggcaac gacatcatcc ggcccgggac cgacccggac
    22861 gacgtggccg agcgcttcga ggcggccgtg gccgacctca ccggggccgt cggccaggtc
    22921 atgatcacca cgggcttcga cacccgcggc gtcccggtgc tcaagcactt gcgcgggaag
    22981 gtcgcgacgt acagcgcgca cgtccgtgcc atcgccgacc gctacgactg cccggtgctc
    23041 gacctctggt cgctgaagtc cgtacaggac cggcgggcct gggacacgga ccggctgcac
    23101 ctctcgcccg agggccacac gcgggtcgcg ctgcgcgccg cgcaggtgct cggcctggag
    23161 gtgccggccg acccggacca gccgtggccc ccgcagcggc cgcgcggctc ggtggacgtg
    23221 acccgggaca acatccagtg ggcccgcgac cacctcgtgc cgtggatcgg ccgacggctg
    23281 cgcggggagt cctccgggga ccacgtggag gccaagcggc cggacctgct gccgctgtag
    23341 cagggtcggg gggccgcaag cggaatcctt cggggtcggc gtgcgttggg atggtcgtag
    23401 ctcgacgacc gtcctgaccc catcctccct ggaggcgctt tgaccggctc ccgtcccttg
    23461 cgtccgcggc tgcgtgccct gcggcccaaa gccttcggtg cggacccgtc cggtgcccgg
    23521 ctggagcgga tccgccgctc gccgaacttc gccgacggcg tcttccagaa cccggtcggg
    23581 gcccggaaca ggccctcggg ctcgatgacg gagttcgcca agatctactt ccagcgggag
    23641 cagcgggtca ggcgcagccc cgccgcgccg atcccggttc atccgacgac cctcgcggac
    23701 ctggcgaagc cgcccgcgac cggcctgcgg ctgacctgga tggggcactc cagcgtgctc
    23761 gcggagatcg acgggcggcg ggtgctgttc gacccggtct ggggcgagcg gtgctccccc
    23821 ttccccttcg ccggccccaa gcgactgcac ccggtgccgg tcccgctggc cgcgctgggc
    23881 ccggtcgacg tcgtggtcat ctcgcacgac cactacgacc acctcgacct gccgacgatc
    23941 aaggagctgg ccggtacgga caccatcttc gccgttccgc tcggtgtcgg cgcgcacctg
    24001 gagcgctggg gcgtaccggc cgaccggctg cacgagctgg actggaacga gagcaccgag
    24061 atcgccgggc tctccctcac ggcgaccccc gcccgacact tctgcggccg cggcctgcgc
    24121 aaccagcagc acaccctgtg ggcgtcctgg gtcgtcgcgg gcgacgagca ccggatctac
    24181 cacagcggtg acaccggcta cttccccgga ttcaaggaga tcggcgccga gcacgggccc
    24241 ttcgacgcca cgatgatcca gatcggcgcc tactcggagt actggcccga catccacatg
    24301 acgcccgagg agggcatgcg cgcccacctc gacctgcagg ggggtacccc gcagggcacg
    24361 atgctgccga tccactgggg caccttcaac ctggccctgc acccgtggga cgagccgggc
    24421 gagggcacgc tgaccgcggc cgagggtgcg ggggcggccg tcgcgctgcc gatcccgggc
    24481 cagccgttcg agcccggcgc ctccggcgcc ccgcacacgc cgtggtggcg gcccttcgtc
    24541 gccggggcgg cgacgggcgg gcggatcgac ggtccgtcgt ccgtgccccc gctgggcgcc
    24601 ggggcagtgg cggggacggc agcgcgcgtg gggtccgcgg cagccggcgg tcaggagaag
    24661 ccggagtccg tcgggtcgta gcgcaccacg cggacagaga ctgcggccgc cccggcacat
    24721 cggggcggcc cggggccggc gtcgtccgga ccggcttccg tccggctgcc gaggggcggc
    24781 gccggggcgg tccacagggc ccgaccggcg cattcgggcg gctgtacgag cgctccaccg
    24841 ggagcgggaa gcacccccac gaagttcgca aactggtact cccgggcgtg gcggaggggt
    24901 ctagcgtggg tattcggtga tcaacaccgg gccccgggaa cgctgggggc cgggccccac
    24961 gtaccgagga cccacatgtc cggactccgc gccgcccgcc atgccacgtc gagactcgcc
    25021 gtcaccggtc ccggccggca gatacgcccc cagctggtgc gcgccgccgt actgcccacg
    25081 ctcgccgccg ggctcagcgg cgccgccgcg gtgatcttca ccctccagct cggcggggga
    25141 gcgggcgagc gcgacgcccg gctgtggccc gtgctcaccg gctgcgccct ccttgtgatc
    25201 ggcgccctcg cggccgccct cctcggggcg cagcgcgccg ccaaggccgt acgggaccgg
    25261 tgcgaggcgc tgcgccgctc cagcgtgcgc ggccgtcacg agctgcgcac ggccgccgat
    25321 cggctggacc ggggcgagac cccggcccgc cccgtgcgcg gtggcccgag ctccccggcg
    25381 cccggcgggg acccggccgg cctggacgag ttctggctgc tctcccagga gctgcgcagt
    25441 gcccgcgaac aggcgcacac caccctgctg cggctggccg gaccggccac cccgtccgac
    25501 agcgagcgca aggtcgaggt cttcgtcaac ctcgcgcggc gcctccagtc cctcgtgcac
    25561 cgcgagatct cgctgctgga cgagctggag gacacggtcg aggacccgga cctgctcaag
    25621 gagctcttcc acgtcgacca cctcgccacc cgcatccgcc gccacgcaga gaacctcgcc
    25681 gtactgggcg gcgccgcctc ccggcgccag tggacccggc ccatcgatct gagcgaggtg
    25741 ctccgctcct cggtcgcgga ggtcgagcag tacacccggg tcaaggtcgt gcccccggcc
    25801 ggcggcagcg tccgcgggca tgccgtcgcg gacgtggtgc acctgctggc cgagctcgtc
    25861 gagaacgcca ccgtgttctc cgcccccgac acggacgtgg tgctgcgcgc cgagcgggtc
    25921 accgccggga tcgccgtcga ggtggaggac cgggggctcg gcatgccggc cgaggaacag
    25981 caccggatga actccctgct gggcgacccc gaccaggtca gcgtccggag cctgctggcg
    26041 gacggacgga tcggcctttt cgtcgtgtcg gcactggccc gccggcacgg gatcgccgtc
    26101 gagctcaagt ccaacatcta cggcggtgtg ctcgccgtgc tggtgctgcc gcaggagctg
    26161 ctgggagccg aagtgccttc cgcggccgac gcggcggggg gctcacgggc cacctcgtgg
    26221 gggaccgggc agggggcggc ggccgcgccg ctggagccgg tccggatgga cctgccgggg
    26281 cccgggccgc ggcccgcgcg cgcacccgta cccgtaccgg tgatcgtcgc ggaaccggcg
    26341 tccccgcccg cgccgcggcc cggtacgacg gtcgggcccg tgccctcccc ccggaccggt
    26401 gccgatcccg cgttcggccc tccgtccgat ccgccgcccg gtgccggggc gatggcctgg
    26461 tcggcgcccg ccacggcccc ccggggcggc cccgtgccgg gtccggccac cggggcggtg
    26521 gcctggtcgg ccccggagcc ctcggcccct tccgcacccg gcgggcccga cacgggcgac
    26581 cggccgctgc tgccccggcg ccgcgcccag gagcacctcg cgccccagct gcgcgaggcc
    26641 cccgctcccc ggcgggccgc ggactccgag caacccgtcc acgacccggg cctgatggcc
    26701 gcgttccaac gcggcttcgg cctcgcccag tcggagaacc aggcatgacc ccgacccctc
    26761 atcccctcag caaggagcgc acccccatgg gcggcgaagt ggcgacgaag accggcagcc
    26821 ggctctcgga tctcgactgg ctgctcagcg gcctggtgca acgcgtgccg tacacgcgca
    26881 gcgccgtact cctcaccgcc gacgggctcg tgacctgcgt gcacggtctg gacgccgaca
    26941 gcgccgacca tatggcggcc ctcgcgtcgg ggctctactc gctcggccgc agcg
//
