LOCUS       NZ_BMVL01000004        46366 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence04, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000004
VERSION     NZ_BMVL01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 640938)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 269502
            Orig. end                         :: 315868
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..46366
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="4"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..46366
                     /SMILES="C(C)=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..46366
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:26366](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..26366)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    complement(22..36)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.87"
                     /tool="antismash"
     gene            complement(790..1761)
                     /locus_tag="IE257_RS12210"
                     /old_locus_tag="GCM10010343_25170"
     CDS             complement(790..1761)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380149.1"
                     /locus_tag="IE257_RS12210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25170"
                     /product="glycosyltransferase"
                     /protein_id="WP_189967729.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.5e-14,
                     bitscore: 48.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFSQPAARRPDPGTGPVAVIVVTWNSAEVLPEFLASLPEGTAGL
                     DWRLVVADNDSADGTVDLIRSLAPDATIVQTGRNAGYAAGVNAALAAAAAWDGGFGTAL
                     VCNPDVRMRRGCAKVLVDALGEALPGGGRVGISVPLLYEEDGRTLLLSLRRESRVTRAL
                     GEAVLGNRRAGRFPRWSELVTDPVAYERATVADWATGALMAVSGECLQACGAWDESFFL
                     YSEETEYCLRARDLGFVTRLEPAATATHLGGDSQVSPRLWTLLTLNRVRLYGRRHGPAA
                     TTAFRAAVLLREGSRALLGRPASLAAAKALASPSALRATPGP"
     gene            complement(1707..3722)
                     /locus_tag="IE257_RS12215"
                     /old_locus_tag="GCM10010343_25180"
     CDS             complement(1707..3722)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380179.1"
                     /locus_tag="IE257_RS12215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25180"
                     /product="O-antigen ligase family protein"
                     /protein_id="WP_189967731.1"
                     /sec_met_domain="Wzy_C (E-value: 1.8e-10, bitscore: 36.1,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLGEIVAVLRRRWYVMVPLTLISLLAGAHLYRSVPVAYQSESSV
                     ALLDSTAVAELAPAFGNPIANAGGSLVVTADVLIRTLSGTDAARDLQGIGVTDPYTVGF
                     AANTSGPMLTLTVTGTDRAKVLEETNKLTAFAGETLNALQAAAKVKPAYMVQTAPVVLP
                     QTPVPQMKSRYQQVLGVVILGTTTAFTLSFLTDSLLAALRRRRAASAAPARGRGRRKPW
                     GRQLDATALLSCYLALAFFIPSNLTLPGMGGVGTPANVFALLCLFWYLAAWITGRILPA
                     PGTRLPRVVMCLLAFSVLGSYLANAMRGSSHKEVLAADRGLIGLLVWVSLVVLVSAGIQ
                     DRDRLDVLLRRAVVMGTVVAAIGFYDFFTATNIADSISIPGLKSGVAQITTLDRGSFTR
                     PRSTTAQPLEFGGMLAILLPFAVQQAFDPVRRHLRAWRRWGPVVLMGGALPLTVSRTSI
                     IGALIVVLVMVLRWKPERRWAAIGLLMGSVACFKVIIPGLIGTITALFASFLTNSDSST
                     QARTVKYSAIVPYLGERPLFGRGSGTFLPELFFFTDNQYMLTLAEMGLVGLLALLVLLF
                     TGIHQGGAIRRLARTESDRELGQAFFASALVSLVIAATFDALSFPMFAGVFFLTIAAGG
                     SYLGFIRRTAPQPATVESPCSSASQPPAARIRVPAP"
     gene            3803..4498
                     /locus_tag="IE257_RS12220"
                     /old_locus_tag="GCM10010343_25190"
     CDS             3803..4498
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380166.1"
                     /locus_tag="IE257_RS12220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25190"
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="WP_189967734.1"
                     /transl_table=11
                     /translation="MSPGELVRALRRRWYVLIVAAVLTAAGAVQVLHPTQTYLSTAIVV
                     LKPPVTANQPNQLANLQPPLAAVSYAAVQQLESPAGAAELRAAGVSGTYRLIPRNSGTS
                     VTPRYLIPSLQIQAEQDRPVAADTAVRKIIEIYTKHLTDLQTQQGVPDSARMSVTLLVP
                     PTAVVQTGTKSRGLAGAALLGGVGGVVAALWTDRLLTRRSRRRRTAADAGPVGRAEEPE
                     RAPLVGAAR"
     gene            complement(4516..5565)
                     /locus_tag="IE257_RS12225"
                     /old_locus_tag="GCM10010343_25200"
     CDS             complement(4516..5565)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431011.1"
                     /locus_tag="IE257_RS12225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25200"
                     /product="glycosyltransferase"
                     /protein_id="WP_189967736.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.4e-27,
                     bitscore: 91.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVSVVIPCYKYGHFLADCVKSVLDEQEGVDVRVLIIDDASPDD
                     SAEVARALAAADPRIEVRVHESNKGHIATYNEGLLEWADGDYVALLSADDRLVPGALVR
                     AAALLDAHPEAGFCYGRPLRFQHGGPLPAARTRSTGSVVYPGRWWLDRRFREGTGCITS
                     PEVVVRTSLQRKVGGYDPELPHAGDIEMWMRLAAHADVGYVRGADQAFYRVHGNNMSTT
                     DFGGQLDDLRQRLVAFDSVLDKCGGLLPGSDRLALAARTRLARYALRRAYRAYDRGRTA
                     VVPVDELVEFAAECLPGDYTSLAEYRALLRRRRIGARAMPYLQPLVLSAVADRGREWLW
                     WRSWKRRGI"
     gene            complement(5562..8861)
                     /locus_tag="IE257_RS12230"
                     /old_locus_tag="GCM10010343_25210"
     CDS             complement(5562..8861)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431012.1"
                     /locus_tag="IE257_RS12230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25210"
                     /product="DUF4082 domain-containing protein"
                     /protein_id="WP_189967738.1"
                     /transl_table=11
                     /translation="MNRRTRLLRYGLFTVIAALMATVLPPAALAGAVDPCGPGTNAIVC
                     ENSKPGTPMSDWFAPSAYGDIKGFPAQTSVQAGDTVQFKVQSPTPYRVSVYRLGHYGGD
                     GARLMSTAAQAAQTYPANFAPGGAPQTCAKKAATGLVDCGNWPVTTTWTVPADAVSGLY
                     VVNFDQADGNGVMPYPFVVRNDASHSDIVVQTSDQTWQAYNNYGGQDLYDGGGPAPDGR
                     AYEVSYNRPMDIGGDNGIYGSEFQMVAWLERNGYDVSYMSGVDMSVRGGTLLRNHKVFL
                     SSGHDEYWTQEQFTNALNARRAGVHQTYFSGNEVFWKTRLAPSIDGAGTANRTLVSYKE
                     TKLSFPQPNGIPDPSGIWTGTFMDPASATGGRPYQPQNQLTGSMFSVNGYRSDAITVPG
                     TFAKQRLWRNTTVANLTPSQTATFPTGTLGYEWDSDVENASRPAGQITMSSTTVDIEDG
                     KLLKDYGNTYGNGTATHSLVAFRDQTSHALVFGAGTVQWSWGLTNMPTGNPDDAVVTAD
                     KRMQQATVNVFADMGVQPKSLQSDLIASTASTDSVGPGVTVTTPAANATVPALRPVTIT
                     GTAADTGGGVVARVEVSTDGGTTWKATTGLGSWSYKWTPTVQGAAQIKVRAVDDSVNIG
                     ATTTVPLTVGPQQCPCTVWPAAAVPGTVNAGDGSAVELGVKIRSSVAGSITGVRFYKSP
                     ANTGTHTGSLWSSTGQRLATGTFTNETASGWQQLNFATPVPVKANTTYVASYFAPHGGY
                     SFDTTFATGDAGLAPLTALKSGTDGGNGVYRYSGTGGFPSTASSGSNYWVDAVLDTSTA
                     STTPPSVTATSPQSAATGTQITAAVSATFSNAIDADTLVFSVKDSGGAAVPGTKVLGAS
                     NSATFTPSSELALNSTYTASVQASDLWGNAMAAPVTWNFTTSPNPPAVNCPCTLWNGTT
                     TPSTANVGDDANSVELGTRFQSAVNGYITGVTFYKGPGNTGTHTGSLWSASGTLLATGT
                     FGSETLTGWQQLQFATPVPITAGTTYVASYHAPNGNYSVDGGYFAGAHRSYPLVAPADT
                     AGSANGLYKYGAATAFPTNTFGSVNYWVGPIFTTTAPPALQEGLSTEVSGQ"
     misc_feature    8846..8861
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.7"
                     /tool="antismash"
     misc_feature    8863..8877
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.1"
                     /tool="antismash"
     gene            complement(8894..10009)
                     /locus_tag="IE257_RS12235"
                     /old_locus_tag="GCM10010343_25220"
     CDS             complement(8894..10009)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386286.1"
                     /locus_tag="IE257_RS12235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25220"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_189967740.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.4e-105,
                     bitscore: 348.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQIPLVDLKAAHAEVAEELRAGFDRVLADTAFIGGAEVRAFERE
                     YAEFAGVGHCVGVANGTDALELALRASGVGVGDEVVLPANTFIATAGAVARIGARPVLV
                     DCLPDTLLMDPRAALEAVGGATRAVVPVHLYGQCADTAALAAGLPSHVRIVEDAAQSQG
                     ATRDGRSPGSGGIAATSFYPGKNLGAYGDAGAVVTDDEESADLVRALANHGGIAKYRHD
                     VAGFNSRLDGLQAVVLRAKLARLADGNAARRAAAARYDELLADLAAAGQVTLPVTAAGN
                     VHVWHLYVVRVADADRDAVVGKLNAEGIGAGVHYPAPVHLTPAFGRLGHGRGDFPHAEQ
                     AADRMLSLPLFPQITAAQQQRVVDTLRNALR"
     misc_feature    complement(9950..9952)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10006..10776)
                     /locus_tag="IE257_RS12240"
                     /old_locus_tag="GCM10010343_25230"
     CDS             complement(10006..10776)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431014.1"
                     /locus_tag="IE257_RS12240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25230"
                     /product="NeuD/PglB/VioB family sugar acetyltransferase"
                     /protein_id="WP_189967742.1"
                     /transl_table=11
                     /translation="MSGPQQRTEDLLIVGAGGFARETAQAVRDAGAAAAAYGRAPRWRL
                     AGHLDDDPALHGREVDGVPVLGGSHLVHQLPDARVVVCVGSPRDYAVRARLVRRLGLSG
                     TRYATVVHPTAVVSGSSLLGAGSVLLAHSVLTAAVRVGSHVAVMPHVVLTHDDRVGDFA
                     TLASGVRLGGGVRLGRGAYVGAGALVREGTTVGAWSLTGMGSTVLADVPPGEVWAGSPA
                     RRLREAGGPALDELRADGEETGRWPETRMGSTVA"
     gene            complement(10773..11942)
                     /locus_tag="IE257_RS12245"
                     /old_locus_tag="GCM10010343_25240"
     CDS             complement(10773..11942)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431015.1"
                     /locus_tag="IE257_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25240"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_229920295.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3e-117,
                     bitscore: 386.9, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.6e-08, bitscore:
                     27.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAVPDAAPDAAPARIPVMVPWLGEEEAQAAADAVLSGWVAQGPR
                     VAEFERAFAERVGAEHGIAVSSCTTALHLALIALDLGPGDEVIVPSLSFIATANAVRYV
                     GAQPVFADVEEATGNLTPATVDAVRTPRTKAVLVVHQGGVPADVHALRAACADWDVALV
                     EDAACGIGATVGGKSVGHGALLAAWSFHPRKVITTGEGGMLTTDDAHWAERLRRLREHG
                     MNVSAAQRHASSKPIVESYLEVGYNYRMTDIQAAVGLVQLGRLDEIVARRRSLAARYTE
                     LLSTAPGLRPVGDPGHGRGNFQSYWVLLAEDFPVGRDELLAVLSEAGISARRGIMASHL
                     EPAYADHGAAALPVTERISRDSLILPLFHTMTREQQDRVVAVLREQAGG"
     gene            complement(11939..12949)
                     /locus_tag="IE257_RS12250"
                     /old_locus_tag="GCM10010343_25250"
     CDS             complement(11939..12949)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (10-229). E-value:
                     2.2e-11. Score: 35.3. Matches aSDomain:
                     nrpspksdomains_IE257_RS12250_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431016.1"
                     /locus_tag="IE257_RS12250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25250"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_229920296.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.2e-15, bitscore:
                     52.4, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.7e-17,
                     bitscore: 57.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRVRGKKILVTGGAGTIGSHVVDQLVDGGAREIVVLDNFVRGRR
                     ANLARALPSGVVEVVEGDIRDAATVRKVTEGAELVFHLAAIRITQCAEEPRLANEVMVD
                     GTFNVLEAAAAAGVGKVIASSSASVYGLAETFPTTERHHPYNNDTFYGAAKAFNEGMLR
                     SFHSMYGLDYVALRYFNVYGPRMDIHGLYTEVLIRWMEKIAAGEPPLILGDGTQTMDFV
                     DVRDIARANLLAAESDLTDEVFNVASGTETSLLQLAQGLLEAMEADRLVPEHGPARAVN
                     GVTRRLADTSQAAGRLGFTPGIDLRSGLRDLVDWWRAERAADTAAASDTAAGTTR"
     aSDomain        complement(12263..12919)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12250_NAD_binding_4.1"
                     /evalue="2.20E-11"
                     /label="IE257_RS12250_NAD_binding_4.1"
                     /locus_tag="IE257_RS12250"
                     /protein_end="229"
                     /protein_start="10"
                     /score="35.3"
                     /tool="antismash"
                     /translation="VTGGAGTIGSHVVDQLVDGGAREIVVLDNFVRGRRANLARALPSG
                     VVEVVEGDIRDAATVRKVTEGAELVFHLAAIRITQCAEEPRLANEVMVDGTFNVLEAAA
                     AAGVGKVIASSSASVYGLAETFPTTERHHPYNNDTFYGAAKAFNEGMLRSFHSMYGLDY
                     VALRYFNVYGPRMDIHGLYTEVLIRWMEKIAAGEPPLILGDGTQTMDFVDVRDIAR"
     CDS_motif       complement(12839..12922)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12250_0001"
                     /evalue="3.20E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE257_RS12250"
                     /protein_end="37"
                     /protein_start="9"
                     /score="26.2"
                     /tool="antismash"
                     /translation="LVTGGAGTIGSHVVDQLVDGGAREIVVL"
     gene            complement(13009..14106)
                     /locus_tag="IE257_RS12255"
                     /old_locus_tag="GCM10010343_25260"
     CDS             complement(13009..14106)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374949.1"
                     /locus_tag="IE257_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25260"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_189967746.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.4e-28, bitscore:
                     95.1, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 5.1e-11,
                     bitscore: 37.7, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDTAKDAGQGAGDTGKGSAPLGVAVVGAGYWGPNLVRNFQSSDQ
                     FRLRWLCDLNVDRARQVLGGYSTVQATGDYEAVLADPEVDAVAVATPAGTHLDVALAAL
                     RAGKHVLVEKPLAATYEDGLRLVDEAEERGLTLMCDHTYCYTPAVGRIREMVRSGELGD
                     IHYVDSVRINLGLVQKDIDVLWDLAPHDLSVLDFILPDHVRPVAVAAHGADPIGAGQSC
                     VAYLTLQLSTGAIAHVHVNWLSPTKVRTTMVGGSKRTLVWDDLNPTQRVAVFDRGVDLS
                     APQEIGADERRDMLVSYRTGDMVAPAIGEKEALRSMVEEFAASIRTGRAPLTDGRAGLK
                     VLDILEAASRSLEFRGAVVGLRTGR"
     misc_feature    complement(14041..14043)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14480..14496)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.93"
                     /tool="antismash"
     gene            14487..15374
                     /locus_tag="IE257_RS12260"
                     /old_locus_tag="GCM10010343_25280"
     CDS             14487..15374
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431019.1"
                     /locus_tag="IE257_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25280"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_229920297.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.5e-13,
                     bitscore: 44.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSIVIPAHNEGRVIGRLLDALLADTSATGADIVVVCNGCTDDTA
                     RVAGERGDRVRVVEVPTPSKHHALRVGDEHARGFPRLYVDADVVVGAADVRALLGALDR
                     SPELLAVAPGRDIPLAGCAWPVRAYYRVWQRLPAVREGLFGRGVIAVTEPGHARIAALP
                     PLMADDLAASLAFGPGERRVVEEARVVVRPPRTWSDLIRRRVRAATSSAEYERFRAERQ
                     AEAPQQPPGTERTERTARTGTADLRALLWARPALLPGVVVFVVAALAARRGSRKAIRDQ
                     DFSTWLRDESSRQG"
     gene            15502..16893
                     /locus_tag="IE257_RS12265"
                     /old_locus_tag="GCM10010343_25290"
     CDS             15502..16893
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386003.1"
                     /locus_tag="IE257_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25290"
                     /product="MFS transporter"
                     /protein_id="WP_189967751.1"
                     /transl_table=11
                     /translation="MYLADRSAPAGAEPAPDRGPVRAAAVAPTVLALGTVSLITDISSE
                     MVTAVLPLYLIAGLGLSPLGFGALDGVYNGVSALVQLTGGHLADRVRNHKLIAGIGYGL
                     SALCKPLLLFAHSLGPISVILTLERTGKGLRTAPRDALISLSTPPELQGRAFGVHRAMD
                     TTGALLGPLAAFLILSVAVDGYDAVFGVSACVAALGVVVLMLFVPSGDGDTRPRPRPRP
                     PVPRTAEADSVDAAAEPAAVAAAAAVPAADRPAPVRLRDALGLLRLPRLRNLAICAVLL
                     GLTTVSDAFVYLLLQRRTGIGDQWFPLLPLGTAAVFLVLAVPAGALADRIGRRTVFLTG
                     HALLLAGYALLLWAPDQPALPYLVLALHGMFYAATDGVLPAAVAATVPAELRATGLALV
                     GTGQALARFGCSLAFGAAWTLWGAGPALAAAAAGLLCCAAVAGFVLRPAAPDVPLPDPN
                     RTGSP"
     misc_feature    15952..15954
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16910..17923
                     /locus_tag="IE257_RS12270"
                     /old_locus_tag="GCM10010343_25300"
     CDS             16910..17923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135557.1"
                     /locus_tag="IE257_RS12270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25300"
                     /product="TolB-like translocation protein"
                     /protein_id="WP_189968317.1"
                     /transl_table=11
                     /translation="MSLSRRLIVLAVAVLLLGGLAAALVLRAASRDDKPSAGGPTVAPG
                     TVTLTRPGTLTFLNGGQGPHRGALASVPADAPDSERTASELNCRRFYAASGTGVCLRST
                     PGALAQDNKALIVDSELRTLRSFPLAGTPSRARVSPSGRFAAWTVFVSGESYGAAFFST
                     RTAIVDTRTGKLEANLEEFTITMDGREHRAQDVNFWGVTFSKDDDTFYATLSTGGETHL
                     VKGSISGRSVTTLAKNVECPSLSPDETRIAYKKRVRAGASLWREHVMDLGTLREHALAE
                     KRSVDDQAAWLDDRTLAYGLPTDGAADSTDLWTVPADGSGTPRLLAPGASSPVRLG"
     gene            complement(17976..18821)
                     /locus_tag="IE257_RS12275"
                     /old_locus_tag="GCM10010343_25310"
     CDS             complement(17976..18821)
                     /NRPS_PKS="Domain: Abhydrolase_1 (27-140). E-value:
                     1.1e-17. Score: 56.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS12275_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="IE257_RS12275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25310"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_189967753.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-14, bitscore: 49.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.8e-09, bitscore:
                     33.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTETVRAEDGATVHVRLHRRPEEPSAPVLVCMPAMGTRAVSYTP
                     LAEALVAAGFQVALGELRGQGTSSVRVRRGVRYGYHEMVTYDYPALFRAVAAAFPGAPR
                     HLLGHSLGGQLGTLYLSREPHMAAGAILVGAPSCHWRGWPFPRSLGMLAGFQLAALFAS
                     VYGYFPGRRIKVLGNDSAQILRDMATQVRTGRYDVPSSPVDFEPWLAKLDLPVLAVTVR
                     GDNMAPPGGVRGLSDKLTSARVTHWELVLGDGTRGSRHYGWIRDNAGLVERVRTFVDRA
                     "
     aSDomain        complement(18402..18740)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12275_Abhydrolase_1.1"
                     /evalue="1.10E-17"
                     /label="IE257_RS12275_Abhydrolase_1.1"
                     /locus_tag="IE257_RS12275"
                     /protein_end="140"
                     /protein_start="27"
                     /score="56.4"
                     /tool="antismash"
                     /translation="PVLVCMPAMGTRAVSYTPLAEALVAAGFQVALGELRGQGTSSVRV
                     RRGVRYGYHEMVTYDYPALFRAVAAAFPGAPRHLLGHSLGGQLGTLYLSREPHMAAGAI
                     LVGAPSCHW"
     CDS_motif       complement(18477..18524)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12275_0001"
                     /evalue="2.50E-04"
                     /label="NRPS-te1"
                     /locus_tag="IE257_RS12275"
                     /protein_end="115"
                     /protein_start="99"
                     /score="13.7"
                     /tool="antismash"
                     /translation="PGAPRHLLGHSLGGQL"
     gene            complement(18836..19999)
                     /locus_tag="IE257_RS12280"
                     /old_locus_tag="GCM10010343_25320"
     CDS             complement(18836..19999)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.5"
                     /locus_tag="IE257_RS12280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25320"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_268251399.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.3e-21, bitscore:
                     70.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.1e-20, bitscore:
                     68.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 9.7e-29, bitscore:
                     95.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVEESRSRSEWKQTFRTFADEVMAPHVRRYDEERTFPVPIHERA
                     AAEGILNAAFPEELGGAGLSYTEFAEGISELSAVCPGMTWTLVFNRGALHPVVAAGTAE
                     QKELFVTRLLKDNGYAALGLTEPENGSNLLAAGTRAVRTESGWLLNGGKCMSGNGTVAD
                     VFIVLANTVVDNRKRGLSFFAVPRDAAGVTVSEDIDKAAFRCLPTPAVTFRDVALEPVS
                     LIGRAGDGEFLLNELLATIRIGGAACGTGIVAAMLRDALTWVGERRVYPDDRMDTLSHV
                     QLTLGRLYVELCAARKLLEEATGLADRGLPFGRESSMAKYAATELAVRASNEILQLYGW
                     RGIAADYGVEKRWRDARALTIFEGSSEIQLLNVFREMRRMATSEGGL"
     gene            complement(20001..26366)
                     /locus_tag="IE257_RS12285"
                     /old_locus_tag="GCM10010343_25330"
     CDS             complement(20001..26366)
                     /NRPS_PKS="Domain: ACP (7-77). E-value: 8.2e-15. Score:
                     46.9. Matches aSDomain: nrpspksdomains_IE257_RS12285_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (100-516). E-value:
                     8.2e-174. Score: 570.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS12285_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (620-916). E-value: 1.1e-103.
                     Score: 338.6. Matches aSDomain:
                     nrpspksdomains_IE257_RS12285_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (966-1117). E-value: 1.3e-17.
                     Score: 56.6. Matches aSDomain:
                     nrpspksdomains_IE257_RS12285_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1419-1596). E-value: 1.6e-49.
                     Score: 160.2. Matches aSDomain:
                     nrpspksdomains_IE257_RS12285_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1673-1754). E-value: 2.9e-18.
                     Score: 58.0. Matches aSDomain:
                     nrpspksdomains_IE257_RS12285_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_ER (1813-2118). E-value: 9.7e-71.
                     Score: 230.4. Matches aSDomain:
                     nrpspksdomains_IE257_RS12285_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.5"
                     /locus_tag="IE257_RS12285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25330"
                     /product="type I polyketide synthase"
                     /protein_id="WP_189967757.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.5e-87, bitscore:
                     287.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 7.5e-173, bitscore:
                     570.4, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1e-102, bitscore: 338.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.1e-41, bitscore:
                     136.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-13, bitscore:
                     46.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 1.1e-12, bitscore: 42.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.6e-21, bitscore:
                     71.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDTELETWLRRRIAELARLGSGEDISVHEPLAAYGLSSIDAVAL
                     AGELGALLDRKVSPTIAYEYPTLREILEHLRDGRPERGATAAPQRAATGTTPDEPVAII
                     GMGCRFPGADGPEAFWELLERGGDAIGRVPDDRFARWGGGNGGTDRAALGGFLTGIGGL
                     DLDFFGINEHEAAKLDPQQRLMLEVAWEAVEDAGLDPYGLAGSPTGVFIGISSSDYRDA
                     LANSPSADAYSLLGGASSVAANRLSYLLDLRGPSLAVDTACSSSLVAVHLACDAIRRGE
                     CDVAIVGGVNVILSPAITEAFDKSGVMAPDGRCKTFSAQADGYVRSEGAGVVVLKPLSQ
                     ALRDGDRVSAVIRGSAVTSDGRTNGLLAPSRRSQEEVVRQALGRAGARPREVGYVEAHG
                     TGTAIGDQIEAAALGGVLNRGRAADRPCAIGSVKTNVGHLEAAAGIAGVIKLALCFEHG
                     ALPPSLHCDEPNPDIDFDGLGLRVQSSLRRWESPDEVGVAGVSSFGFGGTNAHAVLGPA
                     PAATGACEDRPARRPVQLLALSAATEPALHAQAADHAAWAEGLDEDEVGRGSAAATQVR
                     GRGGPRGREVRAAFAFADRGELLARLREPFTGARHVPDEAGVVFVFPGQGAQWLGMGRA
                     LIESEPAFDLAVSRCEQAFAPHVDWSLREVLTSQDAAPLLERIDVVQPAVFAMQVGLAA
                     LFRSWGVRPAGVIGHSMGEVAAAHVSGALRLEDAARIICRRSALMMRHRGQGAMALVSL
                     PVSDVRKALEPYGERLSLAAHNGPSTTIVSGETAAVDEFVAAMDAEGVFGRRVKVDVAS
                     HCALLEDLREDLVAELAGLSPRPATVAFHSSLTGERFDTTGLDAAYWWRNLREPVLFAD
                     AVRGAGAAGHRVFLEMSPHPLLSVSVTECLEDEDRDVAAVPAMRRADDRAPYESVAALF
                     EAGCEIDWVAFHAGRPRAGRRLPPYPWQRQEHWVEPAGPRAEGVLVTGSLPVIRDHRVQ
                     ERAIAPAAWMLDAALRELNPEQVGGYGLSDVLVTNSLAVAGEESRQVRVSRRLRAGDEP
                     FLSVESRAAHEHGAAWEEHVSAGWSATGPAPAPADPAAILLRCPRRVETDALYEHLAAS
                     GLSYGDTMRMVTEMWLGDKELLTRLAPPSPRTLGRPLPADVADGAMQSIAGLSVDAGAS
                     GTFVGFGYRRVDVFAPWSGPTLAHVRLRSELDADADTFDCDVTILDPEGQVLVEFTGVS
                     LKRMGNRHSLRFLAVDARPQPRPAEAAGRPGEVVLLTGDAERCVPLVEELRRGGATVSV
                     AALPCGEEDGPRFLEGLPAAARLLVVEPEREAFLALLRSATKSTSTARRELALVTGDVA
                     LPPLLRALEQETVSWSGRAIRVEADALTTRELARDIAAELAVRPDAFCVRYRHGERTLP
                     SLTPVEASAAPAELRPGGVYWITGGQGGLGSTLAVTLAREAGARVVLTGRRAEVDPQLE
                     EAVDAAGGRLLYLQADVTDEAAVRRALDETLRRFGALHGVIHTAGILDDALIGSTSAER
                     MHAITAPKERGARILIDAVAAEDLDFIVLFSSMASLFVTAGQGAYAAGNATLDALTGTV
                     RSRRTPVRTINWGPWAELGMVADPRYQARLLESGLHPMSPEAGAEAFLKALAGTHLQLA
                     VLDVRDEVADGLVARFNRGAGAAGEAGAARPRAAGAARAEDGAGSAAEFVRAELARALR
                     RPPAEIDTSVRFDRLGIDSLLAVSLTRRIGAHFGLELPATFMFNHRTVDAVGLHLEGLL
                     AAESPEPDVRPDAPDAPAATGGTPVESAREITLDEAERHSTVRGYTVVAGPSGLDMRLQ
                     DVPVRRPAPSEVVIDVHAVGVNFIDVLASTGFHPFLSTPPFVPGHEVAGVVHAVGDAVE
                     HVRPGDEVLALTLQGGYAARVTTEAYTVAPLPAGVSFTDSVAMLISGLTAIACLERGAR
                     VDPGDRVLIQAAAGATGTACVQLALHHGATVFGTASTEAKLEHLRALGVQYPINYAEAD
                     FADAVRELSPDQGLDLIVDSLSGDAVGRGLALLRSGGRFVEIGAAGVLDLAVNGRDLFM
                     SSRSFCTVNVGALARDPARLRPLMDRLVELIDAGVFRPAVGGVFPFEEAPRAITQLRNR
                     ANIGKFVITVS"
     aSDomain        complement(20013..20927)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12285_PKS_ER.1"
                     /evalue="9.70E-71"
                     /label="IE257_RS12285_PKS_ER.1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="2118"
                     /protein_start="1813"
                     /score="230.4"
                     /tool="antismash"
                     /translation="LQDVPVRRPAPSEVVIDVHAVGVNFIDVLASTGFHPFLSTPPFVP
                     GHEVAGVVHAVGDAVEHVRPGDEVLALTLQGGYAARVTTEAYTVAPLPAGVSFTDSVAM
                     LISGLTAIACLERGARVDPGDRVLIQAAAGATGTACVQLALHHGATVFGTASTEAKLEH
                     LRALGVQYPINYAEADFADAVRELSPDQGLDLIVDSLSGDAVGRGLALLRSGGRFVEIG
                     AAGVLDLAVNGRDLFMSSRSFCTVNVGALARDPARLRPLMDRLVELIDAGVFRPAVGGV
                     FPFEEAPRAITQLRNRANIGKFVI"
     CDS_motif       complement(20496..20558)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0013"
                     /evalue="3.80E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE257_RS12285"
                     /protein_end="1957"
                     /protein_start="1936"
                     /score="22.6"
                     /tool="antismash"
                     /translation="GDRVLIQAAAGATGTACVQLA"
     aSDomain        complement(21105..21347)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12285_PKS_PP.1"
                     /evalue="2.90E-18"
                     /label="IE257_RS12285_PKS_PP.1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="1754"
                     /protein_start="1673"
                     /score="58.0"
                     /tool="antismash"
                     /translation="AARAEDGAGSAAEFVRAELARALRRPPAEIDTSVRFDRLGIDSLL
                     AVSLTRRIGAHFGLELPATFMFNHRTVDAVGLHLEG"
     aSModule        complement(21105..26066)
                     /complete
                     /domains="nrpspksdomains_IE257_RS12285_PKS_KS.1"
                     /domains="nrpspksdomains_IE257_RS12285_PKS_AT.1"
                     /domains="nrpspksdomains_IE257_RS12285_PKS_DH.1"
                     /domains="nrpspksdomains_IE257_RS12285_PKS_KR.1"
                     /domains="nrpspksdomains_IE257_RS12285_PKS_PP.1"
                     /locus_tags="IE257_RS12285"
                     /monomer_pairings="mmal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(21579..22109)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12285_PKS_KR.1"
                     /evalue="1.60E-49"
                     /label="IE257_RS12285_PKS_KR.1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="1596"
                     /protein_start="1419"
                     /score="160.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GVYWITGGQGGLGSTLAVTLAREAGARVVLTGRRAEVDPQLEEAV
                     DAAGGRLLYLQADVTDEAAVRRALDETLRRFGALHGVIHTAGILDDALIGSTSAERMHA
                     ITAPKERGARILIDAVAAEDLDFIVLFSSMASLFVTAGQGAYAAGNATLDALTGTVRSR
                     RTPVRTINWGPWAE"
     CDS_motif       complement(21639..21737)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0012"
                     /evalue="6.80E-15"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE257_RS12285"
                     /protein_end="1576"
                     /protein_start="1543"
                     /score="47.6"
                     /tool="antismash"
                     /translation="LDFIVLFSSMASLFVTAGQGAYAAGNATLDALT"
     CDS_motif       complement(22008..22106)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0011"
                     /evalue="6.60E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="1453"
                     /protein_start="1420"
                     /score="22.0"
                     /tool="antismash"
                     /translation="VYWITGGQGGLGSTLAVTLAREAGARVVLTGRR"
     aSDomain        complement(23016..23468)
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12285_PKS_DH.1"
                     /evalue="1.30E-17"
                     /label="IE257_RS12285_PKS_DH.1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="1117"
                     /protein_start="966"
                     /score="56.6"
                     /tool="antismash"
                     /translation="AGPRAEGVLVTGSLPVIRDHRVQERAIAPAAWMLDAALRELNPEQ
                     VGGYGLSDVLVTNSLAVAGEESRQVRVSRRLRAGDEPFLSVESRAAHEHGAAWEEHVSA
                     GWSATGPAPAPADPAAILLRCPRRVETDALYEHLAASGLSYGDTMRM"
     CDS_motif       complement(23355..23420)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0010"
                     /evalue="2.30E-03"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE257_RS12285"
                     /protein_end="1004"
                     /protein_start="982"
                     /score="10.7"
                     /tool="antismash"
                     /translation="IRDHRVQERAIAPAAWMLDAAL"
     aSDomain        complement(23619..24506)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12285_PKS_AT.1"
                     /evalue="1.10E-103"
                     /label="IE257_RS12285_PKS_AT.1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="916"
                     /protein_start="620"
                     /score="338.6"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGAQWLGMGRALIESEPAFDLAVSRCEQAFAPHVDWSLREV
                     LTSQDAAPLLERIDVVQPAVFAMQVGLAALFRSWGVRPAGVIGHSMGEVAAAHVSGALR
                     LEDAARIICRRSALMMRHRGQGAMALVSLPVSDVRKALEPYGERLSLAAHNGPSTTIVS
                     GETAAVDEFVAAMDAEGVFGRRVKVDVASHCALLEDLREDLVAELAGLSPRPATVAFHS
                     SLTGERFDTTGLDAAYWWRNLREPVLFADAVRGAGAAGHRVFLEMSPHPLLSVSVTECL
                     EDEDRDVAAVPAMRR"
     CDS_motif       complement(23760..23807)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0009"
                     /evalue="4.30E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE257_RS12285"
                     /protein_end="869"
                     /protein_start="853"
                     /score="15.7"
                     /tool="antismash"
                     /translation="LDAAYWWRNLREPVLF"
     CDS_motif       complement(24015..24053)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0008"
                     /evalue="6.60E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE257_RS12285"
                     /protein_end="784"
                     /protein_start="771"
                     /score="9.9"
                     /tool="antismash"
                     /translation="AAHNGPSTTIVSG"
     CDS_motif       complement(24159..24269)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0007"
                     /evalue="3.60E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE257_RS12285"
                     /protein_end="736"
                     /protein_start="699"
                     /score="57.4"
                     /tool="antismash"
                     /translation="GVRPAGVIGHSMGEVAAAHVSGALRLEDAARIICRRS"
     CDS_motif       complement(24273..24344)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0006"
                     /evalue="5.30E-08"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE257_RS12285"
                     /protein_end="698"
                     /protein_start="674"
                     /score="25.3"
                     /tool="antismash"
                     /translation="LERIDVVQPAVFAMQVGLAALFRS"
     CDS_motif       complement(24456..24512)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0005"
                     /evalue="4.90E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="637"
                     /protein_start="618"
                     /score="27.9"
                     /tool="antismash"
                     /translation="VFVFPGQGAQWLGMGRALI"
     aSDomain        complement(24819..26066)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12285_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="8.20E-174"
                     /label="IE257_RS12285_PKS_KS.1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="516"
                     /protein_start="100"
                     /score="570.4"
                     /tool="antismash"
                     /translation="VAIIGMGCRFPGADGPEAFWELLERGGDAIGRVPDDRFARWGGGN
                     GGTDRAALGGFLTGIGGLDLDFFGINEHEAAKLDPQQRLMLEVAWEAVEDAGLDPYGLA
                     GSPTGVFIGISSSDYRDALANSPSADAYSLLGGASSVAANRLSYLLDLRGPSLAVDTAC
                     SSSLVAVHLACDAIRRGECDVAIVGGVNVILSPAITEAFDKSGVMAPDGRCKTFSAQAD
                     GYVRSEGAGVVVLKPLSQALRDGDRVSAVIRGSAVTSDGRTNGLLAPSRRSQEEVVRQA
                     LGRAGARPREVGYVEAHGTGTAIGDQIEAAALGGVLNRGRAADRPCAIGSVKTNVGHLE
                     AAAGIAGVIKLALCFEHGALPPSLHCDEPNPDIDFDGLGLRVQSSLRRWESPDEVGVAG
                     VSSFGFGGTNAHAVLGP"
     CDS_motif       complement(25035..25079)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0004"
                     /evalue="5.80E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE257_RS12285"
                     /protein_end="444"
                     /protein_start="429"
                     /score="12.2"
                     /tool="antismash"
                     /translation="GSVKTNVGHLEAAAG"
     CDS_motif       complement(25140..25187)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0003"
                     /evalue="3.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE257_RS12285"
                     /protein_end="409"
                     /protein_start="393"
                     /score="12.9"
                     /tool="antismash"
                     /translation="YVEAHGTGTAIGDQIE"
     CDS_motif       complement(25380..25418)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0002"
                     /evalue="6.10E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE257_RS12285"
                     /protein_end="329"
                     /protein_start="316"
                     /score="12.9"
                     /tool="antismash"
                     /translation="FSAQADGYVRSEG"
     CDS_motif       complement(25560..25607)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12285_0001"
                     /evalue="1.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE257_RS12285"
                     /protein_end="269"
                     /protein_start="253"
                     /score="20.4"
                     /tool="antismash"
                     /translation="GPSLAVDTACSSSLVA"
     aSDomain        complement(26136..26345)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12285_ACP.1"
                     /evalue="8.20E-15"
                     /label="IE257_RS12285_ACP.1"
                     /locus_tag="IE257_RS12285"
                     /protein_end="77"
                     /protein_start="7"
                     /score="46.9"
                     /tool="antismash"
                     /translation="TWLRRRIAELARLGSGEDISVHEPLAAYGLSSIDAVALAGELGAL
                     LDRKVSPTIAYEYPTLREILEHLRD"
     gene            complement(26398..28170)
                     /locus_tag="IE257_RS12290"
                     /old_locus_tag="GCM10010343_25340"
     CDS             complement(26398..28170)
                     /NRPS_PKS="Domain: CAL_domain (51-500). E-value: 3.8e-135.
                     Score: 443.2. Matches aSDomain:
                     nrpspksdomains_IE257_RS12290_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="IE257_RS12290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25340"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_189967759.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 4.4e-242, bitscore:
                     801.6, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-91, bitscore:
                     302.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDESFALSPTALDEVRFETVVDALHAHAARIPDHDLFTFLPDGD
                     EAEPSLTFSMLDTRARAVAASLRAQVEPGSRALLLFMPGQDFVVAYFGCLYAGVVAVPA
                     YLPHPAQRARGLLRLAGIAEDAQPAAILTTSAIQAAIETTARSIPELQETAWLAVDEIP
                     DAGGAGWSAPAPDPDSLAFLQYTSGSTGQPKGVMVTHRNLAHNTDLIRTSLGLDHSTVV
                     VGWLPPYHDMGLISMIVAPAMLGIHSVSMPTVAFLQNPVRWLRAISKYRGTLSAAPNFA
                     FDLCTRKVSEEDRATLDLSSWAVATNGAEPVRAESMKRFSAAFASCGFRPETIIPVYGL
                     AESTLLVSGAPIEQPWIFRSFDESELEEGVARIVPQDSPNARVLVSCGISRTLDVAIVD
                     PKRHTRCAPGEVGEIWVAGESVAVGYWQRPDLSREAFEATPSDGGQGPYMRTGDLGFRT
                     EDGLFVCGRIKDVIIVGGRNHYPHDIERTAESAHSAIRPGCVAAFGVTTDGEESVVVAA
                     ELRPGAAAGEDRSESEAVANAVRHAVAQEHRLTARDVVLLPAGTLPKTSSGKLQRGETR
                     KEYLTGRSPWNAQR"
     aSDomain        complement(26671..28017)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12290_CAL_domain.1"
                     /evalue="3.80E-135"
                     /label="IE257_RS12290_CAL_domain.1"
                     /locus_tag="IE257_RS12290"
                     /protein_end="500"
                     /protein_start="51"
                     /score="443.2"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TFSMLDTRARAVAASLRAQVEPGSRALLLFMPGQDFVVAYFGCLY
                     AGVVAVPAYLPHPAQRARGLLRLAGIAEDAQPAAILTTSAIQAAIETTARSIPELQETA
                     WLAVDEIPDAGGAGWSAPAPDPDSLAFLQYTSGSTGQPKGVMVTHRNLAHNTDLIRTSL
                     GLDHSTVVVGWLPPYHDMGLISMIVAPAMLGIHSVSMPTVAFLQNPVRWLRAISKYRGT
                     LSAAPNFAFDLCTRKVSEEDRATLDLSSWAVATNGAEPVRAESMKRFSAAFASCGFRPE
                     TIIPVYGLAESTLLVSGAPIEQPWIFRSFDESELEEGVARIVPQDSPNARVLVSCGISR
                     TLDVAIVDPKRHTRCAPGEVGEIWVAGESVAVGYWQRPDLSREAFEATPSDGGQGPYMR
                     TGDLGFRTEDGLFVCGRIKDVIIVGGRNHYPHDIERTAESAHSAIRPGCV"
     CDS_motif       complement(26716..26778)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12290_0003"
                     /evalue="4.50E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS12290"
                     /protein_end="485"
                     /protein_start="464"
                     /score="13.0"
                     /tool="antismash"
                     /translation="CGRIKDVIIVGGRNHYPHDIE"
     CDS_motif       complement(26863..26949)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12290_0002"
                     /evalue="4.50E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS12290"
                     /protein_end="436"
                     /protein_start="407"
                     /score="38.2"
                     /tool="antismash"
                     /translation="PGEVGEIWVAGESVAVGYWQRPDLSREAF"
     CDS_motif       complement(27571..27630)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS12290_0001"
                     /evalue="7.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS12290"
                     /protein_end="200"
                     /protein_start="180"
                     /score="30.7"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGQPKGVMVTH"
     misc_feature    28665..28680
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.44"
                     /tool="antismash"
     misc_feature    28753..28767
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.07"
                     /tool="antismash"
     gene            28967..29470
                     /locus_tag="IE257_RS12295"
                     /old_locus_tag="GCM10010343_25350"
     CDS             28967..29470
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE257_RS12295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010343_25350"
                     /product="hypothetical protein"
                     /protein_id="WP_189967761.1"
                     /transl_table=11
                     /translation="MTGIEFLASFLRTGRLHGIGIGSTLGEVDRAVRHRFVDVVDEDGR
                     SLRRDYGFVEFYFNAGNEWVMSGGSIELHRLASGRYRAKEWARTMEIAFPRHVAWRDLR
                     DELARIPGAPELTVGDQGGFLEYRASASGVSVLVVDDEEEERGCHAGHGDVWSVSLWAP
                     VRAR"
     gene            29858..31537
                     /locus_tag="IE257_RS12300"
                     /old_locus_tag="GCM10010343_25370"
     CDS             29858..31537
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (312-498). E-value: 2.5e-17. Score:
                     54.9. Matches aSDomain: nrpspksdomains_IE257_RS12300_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114734.1"
                     /locus_tag="IE257_RS12300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25370"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_189967763.1"
                     /transl_table=11
                     /translation="MYVLLVASAFNSLTQRVHAELRDHGHRVAVELALPGAPLGDAVRA
                     HHPDLVIAPMLRTAIPEEIWADRTCLVVHPGPVGDRGPSSLDRAIQDGEPRWGVTVLQA
                     NAEMDAGDVWASVECPVPPVGKSDLYRGEIADAALEAVLLAVERFASGTYTPQPQAAGR
                     ARPLLRQEERRIDWERDGTADVLRALRAADSQPGVQDELLGGEWFLHGGHREERLRGCP
                     GELLATRTGAVCRATADGAVWIPELRARRLPGGPVAAKLPATLALADRLPPLPEVPAPP
                     DSGPHRRTWSDIGYHEDGQAGFLSFSFPGGAMSTAHCRRLLDAYRTACTRPTTVLVLGG
                     GRDFFSNGIHLGVIEAADDPAEESWANINAINDLVEAVLTTTDRLVVSALGGNAAAGGA
                     MLALAADEVWCRSGVVLNPHYRLMGLHGSEYWTYTLPRRVGPSLAERLTAEALPLSAAA
                     AHGLGLVDRTLPCPPGEFTAETERLAVRLAGLPATASRIAGKKAARERDEALRPLAAHR
                     EAELALMRRTFFDPDAPYHALRRAFVRKERPAATPPHLRGPG"
     aSDomain        30794..31351
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS12300_ECH.1"
                     /evalue="2.50E-17"
                     /label="IE257_RS12300_ECH.1"
                     /locus_tag="IE257_RS12300"
                     /protein_end="498"
                     /protein_start="312"
                     /score="54.9"
                     /tool="antismash"
                     /translation="MSTAHCRRLLDAYRTACTRPTTVLVLGGGRDFFSNGIHLGVIEAA
                     DDPAEESWANINAINDLVEAVLTTTDRLVVSALGGNAAAGGAMLALAADEVWCRSGVVL
                     NPHYRLMGLHGSEYWTYTLPRRVGPSLAERLTAEALPLSAAAAHGLGLVDRTLPCPPGE
                     FTAETERLAVRLAGLPATASRIA"
     gene            31694..32749
                     /locus_tag="IE257_RS12305"
                     /old_locus_tag="GCM10010343_25380"
     CDS             31694..32749
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014150954.1"
                     /locus_tag="IE257_RS12305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25380"
                     /product="hydrogenase expression protein HypE"
                     /protein_id="WP_189967765.1"
                     /transl_table=11
                     /translation="MATATQEKVEDPLIHILWINAGLSCDGDSVSLTAAMQPSIEEIVT
                     GVLPGLPKIAVHWPLIDFECGPVGGADTFIEWFFKGERGEIDPFVLVVEGSIPNEKIKP
                     EGYWCGFGDDPETGQPITTSEWIDRLAPKALAVVAIGTCATYGGIHAMEGNPTGAMGVP
                     DYLGWDWTSKAGIPIVCVPGCPIQPDNFSETLTYLLYQAAGSAPMIPLDDKLRPTWLFG
                     ATVHEGCDRAGYYEQGQFAETYDSPLCLVKLGCWGPVVKCNVPKRGWMNGIGGCPNVGG
                     ICIACTMPGFPDKFMPFMDEPPGAKVSTKASGAYGALIRRLRSVTAHTVDEEPKWRQTG
                     RALTTGYRPPW"
     gene            32813..34597
                     /locus_tag="IE257_RS12310"
                     /old_locus_tag="GCM10010343_25390"
     CDS             32813..34597
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124082.1"
                     /locus_tag="IE257_RS12310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25390"
                     /product="nickel-dependent hydrogenase large subunit"
                     /protein_id="WP_189967767.1"
                     /transl_table=11
                     /translation="MTPKTKAAADGSGLVEMAWDPITRIVGSLGIHTKIDFKQKRVAEC
                     YSTSSVFRGYSVFMRGKDPRDAHFITSRICGICGDNHATCSVYAQNMAYGVKPPHLAEW
                     IINLGESAEYMFDHNIFQENLVGVDYCEKMVRETNPGVLELAERTPAPHAGEHGYRTIA
                     DIMRSLNPIEGEFYREALQVSRYTREMFCLMEGRHVHPSTLYPGGVGTIASVQLFTDYM
                     SRLMRYCEFMKKVVPLHDDLFDFFYEALPGYEEVGRRRVLLGCWGALNDPEYCDFTYAN
                     MTDWGRKMFVTPGVVVDGKLVTNDLTEINLGIRILLGSSYYDDWEGQEQFVTHDPLGNP
                     VDPRHPWNQHTIPAPQKRNFDDKYSWVMSPRWFDGKDHLALDTGGGPIARLWSTALSGL
                     VHTDYVQATGHSVVITLPRTMTKPETRFEWKIPKWSNALERNRARTYFQAYAAAIALHC
                     AEKGLAEVRAGRTQTWEKFEVPDEGLGVGFTEAVRGVLSHHMVIRDGKIANYHPYPPTP
                     WNASTRDTFGTPGPYEDAVQNTPIFEENTPENFKGIDIMRAVRSFDPCLPCGVHMYVGG
                     GKTVKTMHVPTGLSGLGG"
     misc_feature    32827..32836
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            34594..35121
                     /locus_tag="IE257_RS12315"
                     /old_locus_tag="GCM10010343_25400"
     CDS             34594..35121
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849711.1"
                     /locus_tag="IE257_RS12315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25400"
                     /product="hypothetical protein"
                     /protein_id="WP_189967769.1"
                     /transl_table=11
                     /translation="MRAAIDGPQAGRRVEEVLDRLAATGDRAACEAAEELVRVLMDFYG
                     AGLARIVEKVGEAPLKAVHDDELVASLLSLHGLHPEDVHTRIGRALAAHGEPLELLGFD
                     EHTGILRLRPSAAPTGCGCGSGGQDGAGRTLEDSLACFAPEVTGVEREPAPAPAPALLQ
                     IGTRPPSPARVP"
     gene            35118..35819
                     /locus_tag="IE257_RS12320"
                     /old_locus_tag="GCM10010343_25410"
     CDS             35118..35819
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262072.1"
                     /locus_tag="IE257_RS12320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25410"
                     /product="DUF5947 family protein"
                     /protein_id="WP_229920299.1"
                     /transl_table=11
                     /translation="MSGPGLRHDAPRAPRGLRRFAGPRPPRPETCELCGVVVPPDGHRH
                     LVQTEQRALVCACTACALLFDRPGAGTGRLRTVPDRYLTDPGHRLDDGAWELLQIPVGV
                     AFFFRNAALDRLVALYPSPAGATESELDPETWQTVLGAGRLSELLEPDVEALLLRRSEG
                     RTACYLVPIDICYELVGRMRLLWQGFDGGAEARAALDTFFEQVERRSRALAETPATPPA
                     ATAARVEDGVR"
     gene            35816..36520
                     /locus_tag="IE257_RS12325"
                     /old_locus_tag="GCM10010343_25420"
     CDS             35816..36520
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742976.1"
                     /locus_tag="IE257_RS12325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25420"
                     /product="DUF6084 family protein"
                     /protein_id="WP_189967771.1"
                     /transl_table=11
                     /translation="MTEFAFTCTGVRADAYAAGPTLVFRLRITAAGGARVHAIALRCQI
                     RIEPARRGYGPAEAEGLADLFGERSRWGNTLQPVQFAQVSVMVPSFTGETETDLVVPCT
                     YDMDIAATRYFQALAEGEVPLLMLFSGTAFTGDAGFRVEPVPWDREASYRMPVAVWREM
                     VEQHFPGCGWLRLPRDTMDELLAFRSRHALASWEATVRTLLDAAAPAEPAAPPGPVRLG
                     AILPRLTERTAP"
     gene            36517..37941
                     /locus_tag="IE257_RS12330"
                     /old_locus_tag="GCM10010343_25430"
     CDS             36517..37941
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262070.1"
                     /locus_tag="IE257_RS12330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25430"
                     /product="hypothetical protein"
                     /protein_id="WP_189967773.1"
                     /transl_table=11
                     /translation="MTTTTTPGSRFAVARQVADAVLLEGYVLYPYRASAAKNRLRWQFG
                     VLVPPAWGHAHEEHVLQQTEILMEPRGEATLALELRFLHAQRRTVQQAEGDGDFTDVPE
                     LHLTDRVLMPWDEGTEERVEVSVPVAELLGDEGVTFPFRRPARVDTEPVVDADGRTVGR
                     LVRRTAEIEGRLRLRAVELPGAYRVFRLRAVVENTSPWTPPAGAGPLDREAALPHSLVA
                     AHLLLGLDSGSFLSMTDPPEWARQAVAACENRHTWPVLAGEPGRADVVLSSPIILEDHP
                     AIAPESAGAMYDATEIDEILALRTAALTEQEKREARGTDARAAAVIDLADSMPPEVLER
                     LHGAVRALREVTGPEQPPLLTELPAEDVVFRPDTPWWDPARADTADPARDRIAIDGASV
                     GPGSRVLLRPGLRRTDAQDLFLQGRTALVEAVLHDVDGGVHLAVTVEDDPGADIRREQG
                     RFLYFQPDEVTPLEDA"
     gene            37938..38486
                     /locus_tag="IE257_RS12335"
                     /old_locus_tag="GCM10010343_25440"
     CDS             37938..38486
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742974.1"
                     /locus_tag="IE257_RS12335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25440"
                     /product="hydrogenase maturation protease"
                     /protein_id="WP_189967775.1"
                     /transl_table=11
                     /translation="MNARVLVAGIGNVFLGDDGFGVETVRALAAHPLPEGVEVVDFGVR
                     GVHLAYQLLDGYDTLLLVDATARGGEPGTLYLIEADGSAGPEPGGAGAPSPPVLDGHHM
                     SPDAVLALLDTLCAGTGATPPRRTLVLGCEPAGVEEGIGLSPPVAAAVPEAVRTALDLI
                     HGRDPDETDRPRRELRRTP"
     gene            38483..38587
                     /locus_tag="IE257_RS39375"
     CDS             38483..38587
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF047034.1"
                     /locus_tag="IE257_RS39375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_372453003.1"
                     /transl_table=11
                     /translation="MKKAVIGGAVAAALAAVLLQMLPDLRRYLRMRRM"
     gene            38723..39118
                     /locus_tag="IE257_RS12340"
                     /old_locus_tag="GCM10010343_25450"
     CDS             38723..39118
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262068.1"
                     /locus_tag="IE257_RS12340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25450"
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="WP_189967777.1"
                     /transl_table=11
                     /translation="MHEMSIAMAVVGQVEEAARAGGAHAVTSVRLQVGELAGVVPDALA
                     FCFELACAGTVLEGAELVTESVTARARCGSCPGTWAVGMPPELCCPGCGRATDVELLSG
                     RELEILSVRWEDGPAGAPTREPIPEEA"
     gene            39122..40003
                     /gene="hypB"
                     /locus_tag="IE257_RS12345"
                     /old_locus_tag="GCM10010343_25460"
     CDS             39122..40003
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_function="GO:0016530 - metallochaperone activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /GO_process="GO:0051604 - protein maturation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hypB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092035.1"
                     /locus_tag="IE257_RS12345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25460"
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="WP_189967779.1"
                     /transl_table=11
                     /translation="MCRVVDLRQAVLAKNDEAAQVLRTELTARGTTVVNLLSSPGSGKT
                     ALLERELLLARERGVAVAALTADLATENDALRLARSGVPVKQVLTDGLCHLEAAMLGRH
                     LDGWLPGDTRLLFVENVGNLVCPAGYDLGESLRVVLASVTEGEDKPLKYPTAFGLAQLV
                     VVTKTDIARAVEFDEAAFRANVEQVNPGVEVVLTSARAGEGLGVLLDRALAVGAGGGAH
                     APVMARQQHAEAHGHGHGHGHAHADAHGHSHGHGHDHDHDDDHDHARDEGHDHDHDGDH
                     EHPHVQTVAQTR"
     gene            40003..42351
                     /gene="hypF"
                     /locus_tag="IE257_RS12350"
                     /old_locus_tag="GCM10010343_25470"
     CDS             40003..42351
                     /EC_number="6.1.2.-"
                     /GO_function="GO:0003998 - acylphosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016743 - carboxyl- or
                     carbamoyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hypF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570316.1"
                     /locus_tag="IE257_RS12350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25470"
                     /product="carbamoyltransferase HypF"
                     /protein_id="WP_189967781.1"
                     /transl_table=11
                     /translation="MEAVQRRRVTVRGVVQGVGFRPYVYTRATGLGLAGHVTNTPEGVV
                     AEVEGAPDAVSRFCERLAADAPPLAVVDAVDHWEVPVAGGAGFTIIASRTGGPARTLVS
                     PDVATCADCLAELADPTDRRHRHPFITCTHCGPRFTIVTGLPYDRAHTTMAAFPLCPDC
                     AREYEDPADRRFHAQPVACPACGPRLRLLTGRPPRESAGADPVAEARRLLAAGAILAVK
                     GLGGYHLACDATHPGAVAELRRRKARGDKPFALMARDLADVERFAHLGPEERQLLTGGV
                     RPIVLLRRRAGTDGPDGVAPRCPDLGVMLPYTPVHHLLLGLPGDPPGPRLLVMTSGNLA
                     GEPIVTDDDEALDRLAALADGWLTHDRPIHVPCDDSVVRVCDGETLTLRRSRGYAPLPL
                     TLPVPVPATLAAGGDLKNAFCLGEGRKAWPSAHIGDMDDLATQHALERAERQLESITGV
                     TPVLLAADRHPGYRSAGWARRAAGARPLVRVQHHHAHIASAMAEHGLGGGRPVIGVAFD
                     GTGYGDDGAVWGGEVLLADYAGYTRFAHLAYVPLPGGDAAVHRPYRMALSHLRAAGIAW
                     TPDLPCTAACPPGELRVLERQLERGLNCVPTSSMGRLFDAVSSVAGICHRAGYEAQAAI
                     ELEGAAYAAHGDGGGHGDGEAGGHGYAFGLYVPPDPGGGPVTADPSPVLAAAVADVRAG
                     TAPALIAARFHGAVAALVTTLCELARERHGLDTVALTGGVFANTLLSSACARPLRARGF
                     TVLRHGRIPPNDGGLSLGQLMVAAAHHTP"
     gene            42376..42735
                     /locus_tag="IE257_RS12355"
                     /old_locus_tag="GCM10010343_25480"
     CDS             42376..42735
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262065.1"
                     /locus_tag="IE257_RS12355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25480"
                     /product="HypC/HybG/HupF family hydrogenase formation
                     chaperone"
                     /protein_id="WP_189967782.1"
                     /transl_table=11
                     /translation="MCLAVPGRVLDIGEKDGTRMATVDFGGVQKEVCLEYLPDLQVGEY
                     AIVHVGFALQRLDEESAKQTLELFAQLGMLQEEFGDPWEQAAAAGGEPWPFADEPEPET
                     APEPVLAAPQEEVQP"
     gene            42732..43925
                     /gene="hypD"
                     /locus_tag="IE257_RS12360"
                     /old_locus_tag="GCM10010343_25490"
     CDS             42732..43925
                     /GO_function="GO:0016530 - metallochaperone activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hypD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948933.1"
                     /locus_tag="IE257_RS12360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25490"
                     /product="hydrogenase formation protein HypD"
                     /protein_id="WP_189967784.1"
                     /transl_table=11
                     /translation="MKYIEEFQDPDLARRLLDDIHATVTRPWALMEVCGGQTHTIIRHG
                     IDQLLPEQVELIHGPGCPVCVTPLEVIDKALEIASRPDVIFCSFGDMLRVPGTGRDLFQ
                     VRSEGGDVRVVYSPLDALRIAQENPARQVVFFGIGFETTAPPNAMTVHQAKKLGIPNFS
                     LLVSHVRVPPAIEAIMQSPSCRVQGFLAAGHVCSVMGMGEYPELAERHRVPIVVTGFEP
                     LDILEGVRRAVRQLERGEHTVDNAYARAVRPEGNPAALAMLEDVFEVTDRAWRGIGVIP
                     DSGWRLSDRYRDFDAEHRFSVTGINTREPAECRSGEVLQGLLKPHECEAFGTLCTPRSP
                     LGATMVSSEGACAAYYLYRRLELGTVPAAAPAASPATAPPATAPTPVSAPLEASPVV"
     gene            43918..44979
                     /gene="hypE"
                     /locus_tag="IE257_RS12365"
                     /old_locus_tag="GCM10010343_25500"
     CDS             43918..44979
                     /codon_start=1
                     /gene="hypE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262063.1"
                     /locus_tag="IE257_RS12365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_25500"
                     /product="hydrogenase expression/formation protein HypE"
                     /protein_id="WP_281063902.1"
                     /transl_table=11
                     /translation="MSDTALDITGWTCPAPLRDRPRVVMGHGGGGALSAELVQHLFAPA
                     FGGDVLAQLGDSAAVSLGGVRLAFSTDSYVVRPLFFPGGGIGDLAVNGTVNDLAMSGAE
                     AAYLSCGFILEEGVEMSVVARVAEAMGAAARAAGVEVATGDTKVVEAGHGDGIYINTAG
                     IGVIPDGVDLRPQRVVPGDVVIVSGEIGLHGVAIMSVREGLEFGVDIQSDCAALGGLVR
                     TMLAVTPDLHVLRDPTRGGLAASLNEIAAASGTGVVIHEGRVPVPAAVANACAILGLDP
                     LYVANEGKLVAFVPREHADAVLDAMRAHPLGRHAAVIGEAVDAHPGLVVARTGLGGTRV
                     VDLPIGEQLPRIC"
     misc_feature    complement(44987..45000)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            45148..45474
                     /locus_tag="IE257_RS12370"
                     /old_locus_tag="GCM10010343_25510"
     CDS             45148..45474
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE257_RS12370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010343_25510"
                     /product="hypothetical protein"
                     /protein_id="WP_189967786.1"
                     /transl_table=11
                     /translation="MPRSDDTRTTGPGTRPGYGDPVRSRSRSRSRNRRRARAPGEPRPH
                     RRAYRRAGAWLAVALGIWAAVAGATLPNGLVLAAGLVVAALAVNRLGAADPRAGRRAKP
                     MAPP"
     misc_feature    45166..45185
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.31"
                     /tool="antismash"
ORIGIN
        1 ggcgctggac gacgctgcgc gcggagcaga tcgtcccctc cttcgacggc cggcacctga
       61 tcacggccga cgacgacggc atcgcggtcc tggacaccct cgcgccccgg cccaccgtgg
      121 tctggcgcga actcggcggc ggcgagcggc tggtcggccg gctcgcccgc actccggccg
      181 gatgcacggg tgtcgtggtg tcgccgcttc ccgacggcac gcaggccgtc gagctctggc
      241 gctgggacct gcccggctgg gagttgcgct cccggctcag gcccgacgcg ttccgccccg
      301 gccgctccgc ggcgctcgcc gccggcagcc tgctggcggc cgacctgcag ccggcggacg
      361 ggtcaccgga caggaccgtc ctgcactgga ccaccgagag cccgctcgcc cgcccgggcg
      421 ccggcccggg catcgacggc gtcgcgccgc acggcccgat cgtcgacggc gaccactgga
      481 cgctcgcggt gcccggcccc gacggcaccg gagtcctcct tcacacgggc gcgggcgccg
      541 gctccgcgcc caccgcgacc gtgttcttcc cgcaggccgg cacgcaggcc gacacaccgg
      601 ccccgggcct tcgccggcac gccgacgcgg tcacccactg gcaccggtcc ggccgtgtcc
      661 tcgccaccac ccccgacgga gccaccctgc tcgccaacct gcgcgtcacg gtcggctgag
      721 gctgaggctg aggctgaggc tgaggctgag gcggggacgg ggacgggggt gctccggtcc
      781 gacgccgtct cacggccccg gcgtggcccg cagggcagac gggctggcca gggccttcgc
      841 cgccgccagg ctcgcgggcc ggccgagcag cgcccgcgag ccctcccgca gcagtacggc
      901 cgcacggaac gcggtggtcg ccgcgggccc gtgccggcgc ccgtagagcc gtacccggtt
      961 gagcgtgagc agggtccaca gccgcggcga gacctgggag tccccgccca ggtgggtggc
     1021 cgtcgccgcg ggttccagcc gggtgacgaa gccgaggtcg cgggcccgca ggcagtattc
     1081 ggtctcctcc gagtacagga agaaggactc gtcccaggcc ccgcaggcct gcaggcactc
     1141 cccggacacg gccatcagcg cgcccgtcgc ccagtccgcg accgtggccc gctcgtacgc
     1201 gaccgggtcg gtgaccagtt cactccagcg cgggaaccgc ccggcccgac ggttgcccag
     1261 caccgcctcg cccagcgccc gggtcacgcg cgactcccgg cgcagcgaga gcagcagcgt
     1321 acggccgtcc tcctcgtaca gcagcgggac gctgatcccg acccggccgc cccccggaag
     1381 ggcctcgccc agcgcgtcga cgagcacctt ggcgcagccg cggcgcatcc ggacgtccgg
     1441 attgcagacc agggccgtgc cgaagccgcc gtcccatgcc gcggcggccg ccagggcggc
     1501 gttcaccccg gccgcataac cggcgttgcg gccggtctgg acgatcgtcg cgtccggggc
     1561 cagcgagcgg atcaggtcca cggtgccgtc ggccgagtcg ttgtcggcga cgaccaggcg
     1621 ccagtcgagc ccggccgtgc cctccggcag cgaggcgagg aactccggga gcacctcggc
     1681 gctgttccag gtgacgacga tgacggctac ggggccggta cccggatccg ggcggcgggc
     1741 ggctggctgg ctgaactgca tggggactcc acggttgcgg gctgcggcgc cgtacgccgg
     1801 atgaacccga ggtagctgcc tccggcggcg atcgtcagga agaacactcc ggcgaacatc
     1861 gggaagctga gggcgtcgaa cgtggcggcg atgaccaggg agacgagggc cgaggcgaag
     1921 aaggcctgcc ccagctcccg gtcggactcg gtgcgggcca gcctgcggat ggcaccgccc
     1981 tggtggatcc cggtgaacag gaggaccagg agcgcgagca gccccacgag gcccatctcc
     2041 gccagggtga gcatgtactg gttgtcggtg aagaagaaca gctcgggcag gaaggtcccg
     2101 gagccccggc cgaacagcgg ccgttcgccg aggtacggca cgatcgcgct gtacttcacg
     2161 gtacgggcct gggtgctgct gtcggagttc gtcaggaacg aggcgaagag cgcggtgatg
     2221 gtgccgatca gcccgggaat gatcaccttg aagcaggcca ccgagcccat cagcagaccg
     2281 atcgcggccc accggcgctc cggcttccag cgcagcacca tcaccagcac cacgatgagc
     2341 gccccgatga tcgaggtccg cgacaccgtc agcggcaggg cgccccccat caggaccacg
     2401 ggcccccagc gccgccaggc acgcaggtgc cgccggaccg gatcgaaggc ctgctgcacg
     2461 gcgaagggca gcaggatggc gagcatcccg ccgaactcga ggggctgcgc cgtggtggac
     2521 cgcggccggg tgaaggagcc ccggtccagg gtggtgatct gggcgacgcc ggatttcagg
     2581 cccgggatgc tgatgctgtc cgcgatgttc gtcgcggtga agaagtcgta gaagccgatg
     2641 gccgccacca ccgtccccat caccaccgcc cggcgcagca gcacgtccag gcggtcgcgg
     2701 tcctggatcc ccgcggagac cagcaccacc agcgagaccc acacgagcag cccgatcaga
     2761 ccgcggtccg ccgcgaggac ctccttgtgg gagctgcccc gcatcgcgtt cgcgaggtag
     2821 gagcccagta cggagaaggc cagcaggcac atcaccacgc gcggcagccg ggtgcccggg
     2881 gcgggcagga tccggccggt gatccaggcc gccaggtacc agaacaggca cagcagcgcg
     2941 aagacgttgg ccggggtgcc caccccgccc atcccgggca gggtcaggtt cgaggggatg
     3001 aagaaggcca gggccaggta gcagctcagc agggcggtcg cgtccagctg ccgtccccac
     3061 ggcttgcggc ggccgcgccc ccgcgccggg gcggccgagg ccgcgcgccg cctgcggagc
     3121 gcggccagca ggctgtccgt caggaaggag agcgtgaagg cggtcgtggt gcccaggatg
     3181 acgacgccca gcacctgctg gtagcggctc ttcatctgcg gcaccggagt ctgcggcagc
     3241 accacggggg ccgtctgcac catgtacgcg ggcttgacct tggccgccgc ctggagcgcg
     3301 ttgagcgtct ccccggcgaa ggcggtcagc ttgttggtct cctccagcac cttcgcccgg
     3361 tcggtccccg tgacggtcag ggtcagcatc ggccccgagg tgttcgcggc gaagccgacc
     3421 gtgtaggggt cggtcacccc gatgccctgc aggtcccgcg ccgcatccgt ccccgacagc
     3481 gtcctgatca gcacgtccgc ggtgaccacc agcgagccgc cggcgttcgc gatgggattg
     3541 ccgaaggcgg gggccagttc ggccacggcc gtggagtcca gtagcgccac cgagctctcc
     3601 gactggtagg ccaccggcac cgaacggtac aggtgggccc ccgcgagcag gctgatgagc
     3661 gtcagcggca ccatcacgta ccagcggcgc cggagcaccg cgacgatctc accgagactc
     3721 atgaacaccc cccgaggaag ccgcaattga tggcgggcct acccatgtcc tggaaagatc
     3781 ggtcacaacg gaaggaatct ttgtgtcgcc tggtgagttg gtccgtgcgc tgcgccggcg
     3841 ctggtacgtc ctgatcgtgg cggcggtgct cacggctgcc ggagccgtcc aagtgctgca
     3901 ccccacccag acgtacctga gcacggcgat cgtcgtgctc aagcccccgg tgacggccaa
     3961 ccagcccaac caactggcga acctgcaacc gccgctcgcc gccgtctcct acgccgcggt
     4021 gcagcagctg gaatcgcccg ccggcgccgc ggagctccgc gccgcgggcg tgagcggaac
     4081 gtaccggctg ataccgcgca acagcgggac cagcgtcacc ccgcgctacc tgatcccctc
     4141 gctccagatc caggcggagc aggacagacc ggtcgccgcg gacacggccg tccggaagat
     4201 catcgagatt tacaccaagc acctcaccga cctgcagaca cagcagggcg tcccggactc
     4261 cgcgcggatg agcgtcaccc tgctggtacc gcccaccgcg gtggtgcaga ccggcaccaa
     4321 gagccgggga ctcgccgggg cggccctgct gggcggggtc ggcggcgtgg tggcggccct
     4381 gtggaccgac cggctcctga cgcgccggag ccggcgccgg cgtactgccg ccgacgccgg
     4441 tccggtgggg cgggccgagg agcccgagcg ggcgcccctc gtgggggcgg cccgctgaac
     4501 ccgacagatg gatcatcaaa tccctcgacg cttccaggac cgccaccaca gccactcgcg
     4561 cccccggtcg gcaacggccg agagcacgag cggctggagg tacggcatgg cgcgcgcgcc
     4621 gatgcgccgg cgccgcagga gcgcccggta ctcggcgagc gacgtgtagt ccccgggcag
     4681 gcactcggcc gcgaactcca ccagctcgtc caccggaacc accgcggtgc gcccccggtc
     4741 gtacgcccgg taggcgcgcc gcagcgcgta gcgggccagc cgggtgcgcg ccgccagtgc
     4801 cagccggtcg gaccccggca gcagcccgcc gcacttgtcg agcaccgagt cgaaggcgac
     4861 gaggcgctgg cgcaggtcgt cgagctgacc gccgaagtcc gtggtggaca tgttgttgcc
     4921 gtggacccgg tagaaggcct ggtcggcccc gcggacgtag cccacgtcgg cgtgggccgc
     4981 gagccgcatc cacatctcga tgtcaccggc gtgcggcagc tccgggtcgt agcccccgac
     5041 cttgcgctgg agactcgtgc ggaccaccac ctcgggtgag gtgatgcacc cggtgccctc
     5101 ccggaaccgc cggtccagcc accaccgtcc ggggtagacg accgatccgg tgctccgggt
     5161 acgggccgcg ggcagcggcc cgccgtgctg gaagcgcagc ggcctgccgt agcagaagcc
     5221 cgcctccgga tgcgcgtcga gcagggccgc cgcgcgcacc agggccccgg ggaccagccg
     5281 gtcgtccgcc gacagcaggg cgacgtagtc cccgtcggcc cactccagca ggccctcgtt
     5341 gtaggtggcg atgtggccct tgttgctctc gtggacccgt acctcgatcc gcgggtcggc
     5401 ggccgccagc gcgcgggcga cctccgcgga gtcgtcgggc gaggcatcgt cgatgatcag
     5461 cacccgaacg tcgacgccct cctgctcgtc cagcacgctc ttgacgcagt cggccaggaa
     5521 gtggccgtac ttgtagcagg ggatcaccac gctgaccgtg ctcactgccc gctcacctcc
     5581 gtggacagcc cctcctgcag ggcgggcggc gcggtggtgg tgaagatcgg gccgacccag
     5641 tagttcaccg agccgaaggt gttcgtcggg aaggcggtgg ccgccccgta cttgtagagg
     5701 ccgttggcac tgcccgccgt gtcggcgggg gccaccaggg gataggagcg gtgcgcgccg
     5761 gcgaagtagc cgccgtccac cgagtagttg ccgttaggcg cgtggtagga ggccacgtac
     5821 gtggtccccg ccgtgatggg caccggcgtg gcgaactgca gctgctgcca gccggtcagg
     5881 gtctcgctgc cgaaggtgcc ggtggcgagc agggtcccgg aggcggacca caggctgccg
     5941 gtgtgcgtac cggtgttgcc ggggcccttg tagaaggtga caccggtgat gtagccgttc
     6001 accgcggact ggaagcgggt gcccagctcc acggagttgg cgtcgtcacc cacgttggcg
     6061 gtgctggggg tggtggtccc gttccacagg gtgcacgggc agttcaccgc cggcgggttc
     6121 gggctcgtgg tgaagttcca cgtgaccggt gcggccatcg cgttgcccca caggtcggag
     6181 gcctggacgg acgccgtgta ggtggagttc agggccagtt cggaggacgg ggtgaaggtc
     6241 gcgctgttgg acgcgcccag caccttggtg cccggaacgg ccgcgccgcc ggagtccttg
     6301 acggagaaca ccagggtgtc cgcgtcgatg gcgttgctga aggtggccga gacggccgcc
     6361 gtgatctggg tgccggtcgc cgcggactgc ggcgaggtgg cggtgacgga gggcggggtc
     6421 gtgctcgcgg tggaggtgtc caggaccgcg tccacccagt agttgctgcc ggaggaggcg
     6481 gtggacggga agcctcccgt gccgctgtag cggtagacgc cgttgccgcc gtcggtgccg
     6541 ctcttcagcg cggtgagcgg ggccaggccc gcgtcgccgg tggcgaaggt ggtgtcgaag
     6601 gagtagccgc cgtgcggggc gaagtaggag gcgacgtacg tggtgttcgc cttgaccggg
     6661 accggggtgg cgaagttcag ctgctgccag ccggacgccg tctcattggt gaaggtgccg
     6721 gtggccaggc gctggccggt gctgctccag aggctgccgg tgtgggtgcc ggtgttggcg
     6781 ggggacttgt agaagcggac gccggtgatc gaaccggcca ccgaggaacg gatcttcacg
     6841 ccgagctcga cggcgctgcc gtcaccggcg ttgacggtgc ccggtacggc cgcggcgggc
     6901 cagacggtgc aggggcactg ctgcggcccc acggtcagcg gcaccgtggt ggtggcaccg
     6961 atgttcacgc tgtcgtccac ggcgcgcacc ttgatctgcg cggcgccctg cacggtcggg
     7021 gtccacttgt agctccagga gccgagtccc gtggtcgcct tccaggtcgt gccgccgtcg
     7081 gtggacacct ccacccgggc gaccacgccg ccgccggtgt cggccgccgt gcccgtgatg
     7141 gtcacgggcc gcagcgccgg tacggtggcg ttcgccgccg gggtggtcac cgtcacgccc
     7201 ggacccacgg agtccgtgga ggcggtggag gcgatcaggt cgctctgcag cgacttgggc
     7261 tggacgccca tgtcggcgaa gacgttgacc gtcgcctgct gcatccgctt gtccgcggtc
     7321 accaccgcgt cgtccgggtt gccggtgggc atgttggtca ggccccagga ccactgcacc
     7381 gtgcccgcgc cgaacaccag cgcgtgcgag gtctggtcgc ggaaggcgac caggctgtgc
     7441 gtggcggtgc cgttcccgta cgtgttgccg tagtccttga ggagcttgcc gtcctcgatg
     7501 tccaccgtgg tggaggacat cgtgatctgc ccggcgggcc ggctggcgtt ctccacgtcg
     7561 ctgtcccact cgtagccgag cgtgccggtg gggaacgtgg cggtctgcga gggagtgagg
     7621 ttcgcgaccg tggtgttgcg ccacagccgc tgcttggcga aggtcccggg caccgtgatc
     7681 gcgtcgctgc ggtagccgtt gacgctgaac atcgagccgg tcagctggtt ctgcggctgg
     7741 tagggccgac cgcccgtggc gctggccggg tccatgaagg tgcccgtcca gatcccgctc
     7801 gggtcgggga tgccgttcgg ctgggggaag gacagcttgg tctccttgta cgagaccagg
     7861 gtccggttgg cggtgcccgc gccgtcgatg ctcggcgcca gacgggtctt ccagaagacc
     7921 tcgttgccgc tgaagtacgt ctggtggacc ccggcccggc gcgcgttcag cgcgttggtg
     7981 aactgctcct gggtccagta ctcgtcgtgc ccggaggaca ggaagacctt gtggttgcgc
     8041 agcagggtcc cgccgcgcac cgacatgtcg acgccggaca tgtagctcac gtcgtagccg
     8101 ttgcgctcca gccacgccac catctggaac tcggacccgt agatcccgtt gtcccctccg
     8161 atgtccatgg gccggttgta gctgacctcg tacgcccgcc cgtccggggc gggaccgccg
     8221 ccgtcgtaca ggtcctggcc gccgtagttg ttgtaggcct gccaggtctg gtcactggtc
     8281 tgcacgacga tgtcggagtg gctggcgtcg ttgcggacga cgaacgggta gggcatcacc
     8341 ccgttgccgt ccgcctggtc gaagttgacg acgtagagcc cggacacggc gtcggccggc
     8401 acggtccacg tcgtggtgac gggccagttc ccgcagtcga ccaggccggt ggcggccttc
     8461 ttggcgcagg tctgcggggc gccgcccggc gcgaagttcg ccgggtacgt ctgggccgcc
     8521 tgggccgcgg tcgacatcag gcgggcgccg tcgcccccgt agtggccgag gcggtagacg
     8581 gagacgcggt acggcgtcgg cgactggacc ttgaactgca cggtgtcgcc ggcctggacg
     8641 ctcgtctggg ccgggaagcc cttgatgtcg ccgtacgcgc tcggcgcgaa ccagtcggac
     8701 atcggtgtgc cgggtttgga gttctcgcac acgatcgcgt tcgtaccggg accgcaggga
     8761 tcgaccgcgc cggccagcgc ggccggcggc aggaccgtgg ccatcaaggc cgcgatcacg
     8821 gtgaagagac cgtaacggag caaccttgtc cgtctgttca tctggacctc attgtttgcg
     8881 tgagcgcggg gggtcagcgc agggcgttgc ggagggtgtc cacgacccgc tgctgctggg
     8941 cggcggtgat ctgcgggaag agggggagcg agagcatccg gtccgccgcc tgttcggcgt
     9001 gcgggaagtc gccgcggccg tggccgagac gaccgaaggc cggggtgagg tggaccgggg
     9061 ccgggtagtg cacacccgcg ccgatgccct ccgcgttgag cttgcccacg acggcgtcgc
     9121 ggtccgcgtc ggcgacccgg accacgtaca ggtgccacac gtggacattg ccggcggcgg
     9181 tgaccggcag ggtgacctgc ccggcggcgg cgaggtcggc cagcagctcg tcgtagcggg
     9241 cggcggccgc cctgcgggcc gcgttcccgt cggccagccg ggccagcttc gcccgcagga
     9301 ccacggcctg cagaccgtcc agccggctgt tgaacccggc gacgtcgtgg cggtacttgg
     9361 cgatgccgcc gtggttcgcg agggcccgga ccaggtccgc gctctcctcg tcgtcggtca
     9421 ccaccgcgcc cgcgtccccg tacgcaccga ggttcttgcc cgggtagaag ctggtcgcgg
     9481 cgatgccgcc gctgccgggg gagcggccgt cgcgggtcgc gccctggctc tgcgcggcgt
     9541 cctcgacgat ccgcacgtgc gacggcagcc ccgccgcgag cgccgccgtg tccgcgcact
     9601 gcccgtagag gtggacgggg accaccgctc gggtggcccc gcccacggcc tccagagcgg
     9661 cccgcgggtc catcagcagc gtgtcgggca ggcagtcgac cagcaccggt cgggcgccga
     9721 tccgggcgac ggcgcccgcg gtggcgatga aggtgttcgc gggcagcacc acctcgtcgc
     9781 cgacgcccac cccgctcgcg cgcagggcca gttcgagggc gtcggtgccg ttggcgaccc
     9841 ccacgcagtg cccgaccccc gcgaactcgg cgtactcgcg ctcgaacgcg cggacctctg
     9901 caccgccgat gaaggcggtg tcggcgagca cacggtcgaa tcctgcgcgt aattcctcgg
     9961 cgacctcggc gtgcgccgcc ttcaggtcga ccagcggtat ctggttcatg cgactgtgct
    10021 ccccatccgt gtctccggcc accggccggt ctcctcgcca tcggcccgca gctcgtcgag
    10081 cgccggacca cccgcctcgc gcagccggcg ggcggggctt ccggcccaca cctcaccggg
    10141 cggcacatcg gccaggaccg tgcttcccat cccggtcagc gaccaggcgc cgaccgtggt
    10201 gccctcgcgc accagcgccc ccgcgcccac gtacgccccg cgccccagcc gcaccccgcc
    10261 gcccaggcgg acgcccgagg cgagcgtggc gaaatccccg acccggtcgt cgtgggtgag
    10321 caccacgtgc ggcatcacgg ccacgtggga cccgacccgg acggccgccg tcagcacgct
    10381 gtgcgcgagc aggaccgagc ccgcgccgag cagcgaggac cccgagacca cggccgtggg
    10441 gtggaccacc gtcgcgtagc gagtcccgga caggcccagg cgccgtacca gccgggcgcg
    10501 taccgcgtaa tcgcgcgggc tgcccacgca caccaccacc cgggcgtccg ggagttggtg
    10561 cacgaggtga ctgccgccca gcaccggcac cccgtcgacc tcccggccgt gcagggccgg
    10621 atcgtcgtcg aggtgacccg cgaggcgcca ccgcggggca cggccgtacg ccgcggccgc
    10681 ggcgcccgcg tcccgtaccg cctgagcggt ctcgcgggcg aacccgcccg cgccgacgat
    10741 cagcaggtcc tcggtccgct gctgcgggcc gctcatccgc ccgcctgctc gcgcagcacc
    10801 gccaccaccc ggtcctgctg ctcccgcgtc atcgtgtgga acagcggcag gatcagcgag
    10861 tcgcggctga tccgctcggt gaccggcagg gcagccgcgc cgtggtccgc gtacgcgggc
    10921 tccaggtgcg aggccatgat cccgcgccgg gccgagatcc cggcctcgga gagcaccgcg
    10981 agcagctcgt cccggccgac cgggaagtcc tcggccaaca gcacccagta cgactggaag
    11041 ttgccccggc cgtgaccggg gtccccgacc gggcgcagac ccggggccgt gctcagcagc
    11101 tccgtgtacc gggccgcgag cgagcgccgc cgggccacga tctcgtccag cctgccgagc
    11161 tgcaccaggc cgaccgcggc ctggatgtcg gtcatccggt agttgtagcc gacctccagg
    11221 tagctctcga cgatcggctt gctgctcgcg tggcgctgtg cggcggacac gttcatgccg
    11281 tgctcgcgca gccgccgcag ccgctccgcc cagtgcgcgt cgtccgtggt cagcatgccg
    11341 ccctcgccgg tggtgatcac cttgcggggg tggaaggacc aggcggcgag cagggcgccg
    11401 tggcccaccg acttgccgcc gaccgtcgcg ccgatgccgc aggcggcgtc ctccaccagg
    11461 gccacgtccc agtccgcgca cgccgcgcgc aacgcgtgca cgtccgcggg caccccgccc
    11521 tggtggacga cgagcaccgc cttcgtcctg ggcgtgcgga ccgcgtccac ggtggccggg
    11581 gtgaggttgc cggtggcctc ctcgacgtcc gcgaacaccg gctgcgcacc cacgtagcgc
    11641 acggcgttgg ccgtggcgat gaacgacagg gaggggacga tcacctcgtc gccgggaccg
    11701 aggtccaggg cgatcagggc caggtgcagg gcggtggtgc acgagctcac cgcgatgccg
    11761 tgctcggcac ccacccgctc cgcgaaggcc cgctcgaact cggcgacccg gggaccctgg
    11821 gccacccagc cggagagcac cgcgtcggcg gcggcctgcg cctcctcctc gccgagccag
    11881 ggcaccatca cggggatccg ggccggggcg gcgtcgggcg cggcgtccgg gacggcgttc
    11941 accgggtcgt ccccgcggcc gtgtcggagg cggcggccgt gtccgcggcc cgctcggcgc
    12001 gccaccagtc caccaggtcc cgcagcccgc tgcgcaggtc gatcccgggg gtgaagccga
    12061 ggcgcccggc ggcctgcgag gtgtccgcga gccggcgggt caccccgttc acggcacggg
    12121 ccggcccgtg ctcgggcacc aggcggtccg cctccatcgc ttccagcagg ccctgtgcga
    12181 gttggagcag gctggtctcg gtgccgctcg cgacgttgaa gacctcgtcg gtcaggtccg
    12241 actccgcggc cagcaggttg gcgcgcgcga tgtcccggac gtcgacgaag tccatggtct
    12301 gggtgccgtc accgaggatc agcggcggct cgcccgcggc gatcttctcc atccagcgga
    12361 tgagcacctc ggtgtagagc ccgtggatgt ccatccgggg gccgtacacg ttgaagtagc
    12421 gcagcgcgac gtagtccagc ccgtacatcg agtggaagct gcgcagcatc ccctcgttga
    12481 aggccttcgc ggccccgtag aaggtgtcgt tgttgtacgg gtggtggcgc tcggtggtcg
    12541 ggaaggtctc ggccaggccg tagaccgagg cggaggaaga ggcgatcacc ttgcccactc
    12601 cggcggccgc ggccgcctcc agcacgttga acgtgccgtc caccatgacc tcgttggcca
    12661 ggcgcggctc ctccgcgcac tgggtgatcc ggatggccgc gaggtggaag accagctcgg
    12721 ccccctcggt caccttgcgc acggtggccg cgtcacggat gtcgccctcg acgacctcca
    12781 ccaccccgct cggcagggcg cgggccaggt tggcccgccg cccccgcacg aagttgtcga
    12841 gcacgacgat ctcgcgcgct ccgccgtcca ccagttggtc caccacgtgc gagccgatcg
    12901 tgccggcccc gccggtgacc agaatcttct tgcctcgtac cctgctcaac gccctgcccc
    12961 cactggattt gttcgtggtc atgcgtgtga atcggactgc ggggacggtc agcgtccggt
    13021 gcgcagtccg acgacggctc cgcggaactc caggctccgg gaggcggctt ccaggatgtc
    13081 cagcaccttc agtccggccc ggccgtcggt cagcggcgcc cgtccggtcc tgatggacgc
    13141 ggcgaactcc tcgaccatgc tgcgcagggc ctccttctca ccgatcgcgg gcgccaccat
    13201 gtcgccggtc cggtaggaga cgagcatgtc ccggcgctcg tccgcgccga tctcctgcgg
    13261 ggcgctcagg tccaccccgc ggtcgaacac cgcgacgcgc tgggtggggt tgaggtcgtc
    13321 ccacaccagg gtgcgcttgg acccgccgac catggtggtg cgcaccttcg tcggggagag
    13381 ccagttgacg tgcacgtgcg cgatggcgcc ggtgctcagc tggagcgtca ggtaggccac
    13441 gcaggactgg ccggccccga tcgggtcggc gccgtgcgcg gcgacggcga ccggccggac
    13501 gtggtccggg aggatgaagt ccaggacgga caggtcgtgg ggggcgaggt cccacaggac
    13561 gtcgatgtcc ttctggacga gccccaggtt gatccgtacc gaatccacgt agtggatgtc
    13621 gccgagttcg ccggagcgga ccatctcgcg gatccggccc acggcagggg tgtagcagta
    13681 cgtgtggtcg cacatcagcg tgagaccgcg ctcctcggcc tcgtcgacca gccgcagccc
    13741 gtcctcgtac gtggcggcca gcggcttctc cacgaggacg tgcttgccgg cgcgcagggc
    13801 ggccagggcg acgtccaggt gcgtgccggc cggggtggcc acggcgaccg cgtcgacctc
    13861 cgggtcggcg aggaccgcct cgtagtcgcc ggtcgcctgg accgtggagt acccgccgag
    13921 cacctgccgg gcccggtcca cgttcagatc gcagagccac cgcagccgga actggtcact
    13981 ggactggaag ttgcggacga gattggggcc ccagtagccc gcgccgacga cggcgacacc
    14041 taagggtgcg gaccccttgc cggtgtcgcc cgcgccctgc cccgcgtcct tcgcggtgtc
    14101 cttcacggcg ttccccttcc ttccgcgcac gccggacggc gtgtcgccaa ctcatggccg
    14161 ggacgcgtgt gatggaggga aatgccgtcg agggcagccc ggacgcctac gcgtgccgtg
    14221 cgtgacctgc tcaacggtga tggcccccca caaccgatgc tctacgtgat acgtgtgccc
    14281 gccccccggc ccggcagcct gttccccaca agcagccgaa cccgtaccgc ccaccgctcc
    14341 gggccgtatc ggcccgttcc ggatcccggc gccgccgaag cgtgccgatt ccggtcggcg
    14401 gcgctcaatc tagtccaccg ggcgtacccc cgggcagagt tggcgtaatc gcctggcgcg
    14461 ggtgttcgac catgcatact gcccgggtga ccagcatcgt gataccggcc cacaatgaag
    14521 gccgggtcat cggccggctc ctcgacgcgc tcctggccga cacctcggcg accggggccg
    14581 acatcgtcgt ggtgtgcaac ggctgtacgg acgacaccgc ccgcgtggcc ggtgaacgcg
    14641 gggaccgggt gcgcgtggtg gaggtgccga ctccctccaa acaccacgca cttcgggtgg
    14701 gcgacgagca cgcccggggc ttcccccggc tgtacgtgga cgccgacgtg gtcgtcggcg
    14761 cggccgacgt acgggccctg ctgggcgcgc tcgaccggag cccggaactc ctcgccgtgg
    14821 cccccggccg ggacattccg ctcgccggct gcgcctggcc ggtccgggcg tactaccggg
    14881 tgtggcagcg gctgcccgcc gtccgtgagg gcctgttcgg ccggggggtc atcgcggtga
    14941 ccgagccggg gcacgcgcgg atcgccgcgc tgccgccgct gatggccgac gacctggcgg
    15001 cctccctcgc cttcgggccc ggggagcggc gcgtggtcga ggaggcccgg gtcgtcgtcc
    15061 gtccgccgcg cacctggtcc gacctgatca ggcggcgggt ccgcgcggcg acctcctccg
    15121 ccgagtacga gcgcttccgg gcggaacggc aggccgaggc gccgcagcag ccaccgggga
    15181 cggagcggac cgagcggacc gcgcgtaccg gaacggccga tctgcgcgcc ctgctgtggg
    15241 cccgaccggc gctgctgccg ggggtggtgg tgttcgtggt ggccgcactc gccgcccgcc
    15301 ggggctcccg gaaggccatc cgcgaccagg acttctccac ctggctgcgg gacgagagca
    15361 gccggcaggg ctgaccccgg ggccgccccg gggcatgcgg ccgaatccct tcgtacgccc
    15421 cactgttggc ccgtacaacc attagggttt ccctcgcgcg ttcgagtgaa ctcagtccgt
    15481 cggcatcggg agctccagag catgtacctc gcggaccgct ccgcgcccgc gggcgcggag
    15541 cccgctccgg accgggggcc cgtccgggcc gccgcggtcg ccccgaccgt cctcgcactg
    15601 ggcacggtca gcctgatcac cgacatctcc tccgagatgg tcaccgccgt cctgccgctg
    15661 tacctgatcg ccgggctggg cctgagcccc ctcggcttcg gggccctcga cggcgtctac
    15721 aacggggtca gcgccctggt gcagctgacc ggcggacacc tcgccgaccg ggttcgcaac
    15781 cacaagctga tcgccggcat cggctacggc ctgtccgccc tgtgcaaacc gctgctgctg
    15841 ttcgcccaca gcctgggccc gatcagcgtg atcctcaccc tggaacgcac cggcaaggga
    15901 ctgcgcaccg ccccgcgcga cgcactgatc tccctgtcca ccccgcccga gttacaagga
    15961 cgcgccttcg gtgtgcaccg ggccatggac accaccggcg cgctgctcgg cccgctcgcc
    16021 gcgttcctca tcctgagcgt cgcggtcgac ggctacgacg ccgtcttcgg cgtcagcgcc
    16081 tgtgtcgccg ccctcggcgt cgtggtgctc atgctcttcg tcccgtccgg cgacggcgac
    16141 acccggcccc gaccccgtcc tcggccgccc gtgccccgta cggccgaggc cgattccgtc
    16201 gacgccgccg ccgaacctgc cgctgtcgca gccgctgccg ccgtccccgc cgcggaccgc
    16261 ccggcccccg tccggttgcg cgacgccctc ggcctgctgc gtctgccccg gctgcgcaac
    16321 ctggcgatct gcgccgtcct gctgggcctg accaccgtca gcgacgcctt cgtctacctg
    16381 ctcctgcaac gccgcaccgg catcggcgac cagtggttcc cgctgctgcc gctgggcacc
    16441 gccgccgtgt tcctggtgct cgccgtgccc gccggggccc tcgccgaccg gatcggccgg
    16501 cgcaccgtgt tcctcaccgg gcacgccctc ctgctggccg gctacgcgct gctgctgtgg
    16561 gcccccgacc agccggcgct gccctacctc gtcctcgccc tgcacggcat gttctacgcc
    16621 gccaccgacg gcgtgctgcc cgcagccgtc gccgccaccg tccccgcgga actgcgcgcc
    16681 accggcctgg ccctggtcgg caccggccag gcgctggccc gcttcggctg ctcgctcgcc
    16741 ttcggcgcgg cgtggacgct gtggggcgcc ggcccggccc tggccgccgc cgcggccggc
    16801 ctgctctgct gcgcggccgt cgccggcttc gtcctgcgtc cggccgcacc ggacgtcccc
    16861 ctccccgacc cgaaccgcac cggaagcccg tgaggccccc cagatgactc tgtcgttgtc
    16921 acgccgcctg atcgtcctcg cggtggcggt actgctgctc gggggtctgg ccgccgcgct
    16981 cgtgctgcgc gccgcctccc gcgacgacaa gccctcagcg ggcggcccga cggtcgcccc
    17041 ggggaccgtc accctcaccc ggccgggcac cttgaccttc ctcaacggcg gtcagggccc
    17101 gcaccgcgga gccctcgcct ccgtcccggc cgacgccccc gactccgagc gcaccgcctc
    17161 cgagctcaac tgccggcgct tctacgccgc ttcgggcacc ggcgtgtgcc tgcgctccac
    17221 accgggcgcg ctcgcccagg acaacaaggc gctgatcgtc gactccgagc tgcgcacgct
    17281 gcgcagcttc cccctcgcgg gaacccccag ccgggcccgg gtatcgccca gcggccggtt
    17341 cgccgcctgg acggtcttcg tctcggggga gtcctacggc gccgcgttct tctccacccg
    17401 gaccgcgatc gtggacaccc gcaccgggaa gctggaggcg aacctggagg agttcacgat
    17461 caccatggac ggccgggagc accgcgccca ggacgtgaac ttctgggggg tcaccttctc
    17521 caaggacgac gacaccttct acgccaccct ctccaccggc ggcgagaccc acctcgtcaa
    17581 gggctcgatc tcggggcgct ccgtcaccac cctcgcgaag aacgtggaat gcccgtcgct
    17641 gtccccggac gagacgcgca tcgcgtacaa gaagcgggtc cgggccgggg cctcgctctg
    17701 gcgcgagcac gtgatggacc tcgggacgct gcgcgagcac gcgctcgcgg agaagcgcag
    17761 cgtggacgac caggccgcct ggctcgacga ccgcaccctc gcctacggcc tgcccaccga
    17821 cggcgccgcc gacagcacgg acctgtggac cgtgcccgcc gacggcagcg gcaccccccg
    17881 gctgctggcc cccggggcct cctccccggt ccgcctgggc tgaacaccgc aggcggaccg
    17941 gggggagcga ccggggcggg ccgggtgggt ccgggtcagg cccggtccac gaaggtccgt
    18001 acccgctcga cgagtccggc gttgtcgcgg atccagccgt agtgcctgct gccccgcgtg
    18061 ccgtcgccca gtacgagctc ccagtgggtc acccgcgcgc tcgtgagctt gtcgctgagc
    18121 ccccgtaccc cgccgggcgg ggccatgttg tcgcccctga cggtcaccgc cagcaccggc
    18181 aggtccagct tcgccagcca gggctcgaaa tccaccggtg aggacggcac gtcgtagcgg
    18241 cccgtccgga cctgggtggc catgtcccgc aggatctgcg ccgagtcgtt ccccagcacc
    18301 ttgatgcgcc ggccggggaa gtacccgtac accgaggcga agagggccgc gagctggaac
    18361 cccgcgagca tccccaggct ccgcggaaag ggccagccgc gccagtggca ggacggggcg
    18421 cccaccagga tcgcgcccgc cgccatgtgc ggttcccggc ttaggtagag cgtgccgagc
    18481 tgcccgccga ggctgtgccc cagcagatgg cgcggcgccc cggggaaggc cgccgccacc
    18541 gcccggaaca gcgcggggta gtcgtacgtc accatctcgt ggtagccgta ccgcaccccg
    18601 cgccgtaccc ggaccgagct cgtgccctgt ccccgcagct caccgagggc cacctggaag
    18661 ccggccgcca cgagggcctc cgccaggggg gtgtaggaga cggccctggt gcccatggcg
    18721 ggcatgcaca ccagcaccgg cgccgaaggc tcttcgggcc tgcggtgcag ccggacatgg
    18781 accgtggcgc cgtcctcggc gcgcacggtc tccgtggtca cttcggtgga cggaattaca
    18841 ggcctccctc actcgtggcc atcctgcgca tctcgcggaa cacgttgagc agctggatct
    18901 cgctcgaccc ctcgaagatc gtgagggcgc gcgcgtcccg ccagcgcttc tcgaccccgt
    18961 aatcggcggc gatgccccgc cacccgtaca actgcaggat ctcgttggag gcacgcacgg
    19021 cgagctcggt cgccgcgtac ttggccatgg agctctccct gccgaagggc agcccccggt
    19081 cggccaggcc ggtcgcctcc tccagcagtt tgcgcgccgc gcacagttcc acgtacagcc
    19141 gcccgagggt cagctgcaca tggctgaggg tgtccatgcg gtcgtccggg tacacccggc
    19201 gctcgcccac ccaggtcagt gcgtcgcgga gcatggcggc cacgatcccc gtcccgcagg
    19261 cggccccgcc gatccggatg gtcgcgagga gctcgttcag caggaactcc ccgtcgccgg
    19321 cccgcccgat caggctgacc ggctccaggg ccacgtcccg gaaggtcacc gcgggcgtgg
    19381 gcaggcagcg gaacgccgcc ttgtcgatgt cctcgctcac ggtcaccccc gcagcgtccc
    19441 gcggaacggc gaagaacgac agaccgcgtt tgcggttgtc caccaccgtg ttggccagaa
    19501 cgatgaacac gtcggcgacg gtcccgttcc cggacatgca cttgccgccg ttgagcagcc
    19561 agccggactc cgtccgcacg gcgcgggtgc cggccgccag caggttcgag ccgttctcgg
    19621 gctcggtgag cccgagggcc gcgtacccgt tgtccttcag gagccgggtg acgaagagct
    19681 ccttctgctc cgcggtgccg gcggcgacca cgggatgcag cgccccgcgg ttgaacacca
    19741 gcgtccaggt catccccggg cagaccgccg acagctcgct gatgccctcg gcgaactccg
    19801 tgtaggacag cccggcgccg cccagctcct cggggaaggc ggcgttgagg atcccctcgg
    19861 ccgcggcccg ttcgtggatc gggacgggga acgtccgctc ctcgtcgtaa cggcggacgt
    19921 gcggcgccat cacctcatcg gcaaaagtgc ggaacgtctg cttccactct gatcgactgc
    19981 gtgattcttc cacgaccatc ctaagaaacg gtgatgacga acttgccgat gttggcccgg
    20041 ttgcggagct gtgtgatcgc ccgtggcgcc tcctcgaagg ggaagacccc gcccacggcg
    20101 ggacggaaca cgcccgcgtc gatcagctcg acgaggcggt ccatcagggg ccggagcctg
    20161 gccggatcac gtgccagggc acccacgttc accgtgcaga aggaacggct gctcatgaac
    20221 aggtcccggc cgttcacggc caggtcgagc acccccgccg caccgatctc gacgaagcgg
    20281 cctcccgagc gcagcagggc cagacctcgg cccacggcgt cgccggagag ggagtcgacg
    20341 atgaggtcca gtccctgatc agggctcagt tcccttactg cgtcggcgaa atcggcctcg
    20401 gcgtagttga tcgggtactg gacgcccagc gcccgcaggt gctccagctt ggcctccgta
    20461 ctcgccgtgc cgaacaccgt ggcgccgtgg tgcagcgcca gctggacgca cgccgtcccg
    20521 gtcgcgcccg ccgccgcctg gatgagcacc cggtcgcccg ggtccacgcg cgccccgcgc
    20581 tccaggcagg cgatcgcggt gagtccgctg atcagcatgg ccaccgagtc cgtgaacgag
    20641 acgccggcgg gcagcggagc caccgtgtac gcctcggtcg tcacgcgggc cgcgtaaccg
    20701 ccctgcaggg tcagcgcgag gacctcgtcg ccgggccgga cgtgctcgac cgcgtcaccc
    20761 accgcgtgca ccacaccggc cacctcgtgc ccggggacga acggcggggt ggacaggaac
    20821 ggatggaagc cggtggacgc cagcacgtcg atgaagttga cgccgacggc gtgcacgtcg
    20881 atgaccacct cgctcggtgc gggcctgcgc acgggtacgt cctgcaggcg catgtcgagc
    20941 ccggacggcc cggccacgac ggtgtaaccg cgcacggtgc tgtggcgctc cgcctcgtcc
    21001 agcgtgatct cccgggcgct ctccaccggc gtcccgcccg tcgcggcggg tgcgtcgggt
    21061 gcgtcggggc gtacgtccgg ctccggggac tccgccgcga gcaggccctc cagatggagc
    21121 ccgaccgcgt ccacggtccg gtggttgaac atgaacgtcg ccggcagttc gagcccgaag
    21181 tgggccccga tccggcgggt gagggagacg gcgagcagcg agtcgatgcc caggcggtcg
    21241 aagcgtaccg aggtgtcgat ctcggccggc gggcggcgca gcgcgcgggc cagctccgcc
    21301 cggacgaact cggcggcgga gccggccccg tcctccgcgc gcgcggcgcc cgcggcgcgc
    21361 ggccgcgccg ccccggcctc cccggccgcg ccggccccgc ggttgaaccg ggccacgagc
    21421 ccgtcggcga cctcgtcccg tacgtccagc accgccagct gcaggtgggt gccggccagg
    21481 gccttcagga aggcctcggc ccccgcctcg ggggacatcg ggtgcaggcc cgattccagg
    21541 agccgggcct ggtacctggg gtccgcgacc atccccagct ccgcccacgg gccccagttg
    21601 atcgttcgca cgggcgtgcg ccggctgcgt acggtgccgg tgagcgcgtc gagcgtggca
    21661 ttgcccgccg cgtacgcacc ctggcccgcc gtcacgaaca ggctggccat ggaggagaac
    21721 aggacgatga agtccaggtc ctccgcggcc accgcgtcga tcaggatccg ggcgccccgc
    21781 tccttcggcg ccgtgatcgc gtgcatgcgt tccgccgacg tcgacccgat cagcgcgtcg
    21841 tcgaggatgc ccgcggtgtg gatcacaccg tgcagggcgc cgaagcgccg gagcgtctcg
    21901 tccagggcgc gccgcacggc ggcctcgtcg gtcacatcgg cctggaggta gagcagccgt
    21961 ccccccgcgg cgtcgaccgc ctcctccagc tgcgggtcga cctccgcccg gcggccggtg
    22021 agcaccaccc gtgcccccgc ctcgcgggcg agggtgaccg cgagcgtgga tcccaggccg
    22081 ccctgcccgc ccgtgatcca gtagacgcca ccgggcctca gctccgccgg ggccgcggag
    22141 gcctccaccg gggtcaggga cgggagcgtg cgctcgccgt gccggtagcg gacgcagaac
    22201 gcgtcgggcc gtaccgcgag ctccgcggcg atgtcgcggg cgagttcacg ggtggtgagc
    22261 gcgtcggcct ccacccggat cgcccgcccc gaccagctca cggtctcctg ttcgagcgcc
    22321 cgcagcagcg ggggcagtgc cacgtcaccg gtcaccaggg cgagctcccg gcgcgccgtc
    22381 gacgtgctct tcgtggcgct ccgcagcagc gcgaggaagg cctcgcgctc cggttcgacg
    22441 acgagcagcc gagcggcggc cggcaggccc tccaggaacc gcggaccgtc ctcctcgccg
    22501 cagggcaggg cggcgaccga gacggtggcc ccgcccctgc gcagctcctc caccagcggc
    22561 acgcagcgtt cggcgtcccc ggtgagcagg acgacctcgc ccggcctgcc ggcggcctcc
    22621 gcgggccgcg gctgcggccg ggcgtccacc gcgaggaagc gcagcgagtg ccggttgccc
    22681 atccgcttga gggagacccc cgtgaactcc acgaggacct gcccctcggg gtcgaggatc
    22741 gtcacgtcgc agtcgaacgt gtccgcgtcc gcgtcgagtt cgctccgcag ccgcacatgg
    22801 gccagggtcg gaccggacca cggcgcgaac acgtcgaccc ggcggtagcc gaaccccacg
    22861 aaggtgccgc tggctcccgc gtcgacggac agcccggcga tggactgcat cgctccgtcc
    22921 gcgacgtccg cgggaagcgg gcggccgagc gtccgcgggg acggcggcgc gagccgggtg
    22981 agcagctcct tgtcgcccag ccacatctcg gtcaccatcc gcatggtgtc cccgtacgag
    23041 agcccggacg ccgccaggtg ctcgtacagg gcgtcggtct cgacgcgccg cgggcaccgc
    23101 aggaggatcg cggccggatc ggccggcgcc ggggccggcc cggtggccga ccagccggcc
    23161 gagacgtgct cctcccacgc ggcgccgtgc tcgtgcgccg cccggctctc cacggacagg
    23221 aacggctcgt cgcccgcgcg cagccgccgc gagacccgta cctgccggga ctcctccccg
    23281 gcgaccgcca gggagttcgt caccaggacg tcgctgagcc cgtatccgcc cacctgctcg
    23341 gggttgagtt cccgcagcgc cgcgtcgagc atccaggcgg cgggcgcgat cgcccgctcc
    23401 tgcacccggt ggtcacggat gaccggcagc gagccggtga ccaggacgcc ctccgcgcgc
    23461 gggcccgcgg gctcgaccca gtgctcctgg cgctgccagg ggtacggggg cagccgcctg
    23521 ccggcgcgcg gccggccggc gtggaaggcg acccagtcga tctcgcagcc ggcctcgaag
    23581 agcgcggcga ccgactcgta cggggcccgg tcgtccgcgc ggcgcatcgc cggtacggcg
    23641 gcgacgtccc ggtcctcgtc ctccaggcac tcggtcaccg agaccgacag cagggggtgc
    23701 gggctcatct ccaggaacac gcggtgaccg gccgccccgg ccccgcggac cgcgtcggcg
    23761 aacagcaccg gctcgcgcag gttgcgccac cagtacgcgg cgtccagccc ggtggtgtcg
    23821 aaacgctccc cggtgaggga ggagtggaag gcgaccgtcg cgggacgggg cgacagcccg
    23881 gcgagttccg cgaccaggtc ctcccggagg tcctccagca gcgcgcagtg cgaggccacg
    23941 tccaccttga cgcgtcggcc gaagacgccc tcggcgtcca tggcggcgac gaactcgtcg
    24001 acggccgcgg tctcgccgga cacgatggtc gtgctcgggc cgttgtgcgc cgcgagcgac
    24061 agtcgctccc cgtagggctc cagcgccttg cgcacgtccg acaccggcag ggagaccagc
    24121 gccatggcgc cctgcccccg gtgccgcatc atcagggcgc tgcggcggca gatgatccgc
    24181 gccgcgtcct ccaaccgcag ggcgcccgag acatgggcgg ccgcgacctc tcccatgctg
    24241 tggccgatga ccccggcggg ccggacgccc caggaccgga agagcgccgc cagccccacc
    24301 tgcatcgcga acacggcggg ctggacgaca tcgatgcgct ccagcagggg agcggcgtcc
    24361 tgcgaggtca gcacctcgcg cagggaccag tcgacgtgcg gggcgaaggc ctgctcgcag
    24421 cgggagacgg cgaggtcgaa ggcgggctcc gactcgatca gggcccgccc cattccgagc
    24481 cactgggcac cctgcccggg gaacacgaag acgacgcccg cctcgtcggg cacgtgccgc
    24541 gcaccggtga acggctcgcg cagccgtgcg aggagctcgc cgcggtccgc gaaggcgaag
    24601 gccgcgcgga cctcccgccc ccgggggccg ccccggcccc ggacctgtgt cgccgcggcc
    24661 gagccccggc ccacctcgtc ctcgtccagg ccctcggccc acgccgcgtg gtccgcggcc
    24721 tgtgcgtgca gggccggttc ggtggcggcc gacagggcca gcagctgtac ggggcgccgc
    24781 gcgggccggt cctcgcaggc cccggtggcc gccggggcgg ggccgagcac cgcgtgggcg
    24841 ttggtgccgc cgaagccgaa ggagctcact ccggccacgc cgacctcgtc gggagactcc
    24901 cagcgccgca gcgaggactg cacgcgcagc ccgagtccgt cgaagtcgat gtccgggttg
    24961 ggctcgtcgc agtgcaggga cggcggcagg gccccgtgtt cgaagcacag cgccagtttg
    25021 atcacgccgg cgatgcccgc cgccgcctcc aggtgcccga cgttcgtctt caccgaaccg
    25081 atcgcgcacg gccggtcggc ggcgcgcccc cggttcagta cgccgcccag ggcggcggcc
    25141 tcgatctggt cgccgatggc cgtgcccgtc ccgtgggcct cgacgtagcc gacctcccgc
    25201 ggccgggcgc ccgcccggcc gagcgcctgg cgcacgacct cttcctggga ccggcggctc
    25261 ggcgccagca ggccgttggt ccgcccgtcg gaggtcaccg ccgagccgcg gatcaccgcg
    25321 gagacgcggt cgccgtcgcg cagcgcctgg ctcagcggct tcagcacgac cacgcccgcg
    25381 ccctcgctgc gtacgtagcc gtcggcctgc gccgagaagg tcttgcagcg cccgtcgggc
    25441 gccatgacgc cggatttgtc gaaggcctcg gtgatcgccg gggacaggat cacgttcacc
    25501 ccgccgacga tggcgacgtc gcactcgccg cgccggatcg cgtcgcacgc gaggtggacg
    25561 gcgacgaggg aggaggagca ggccgtgtcg acggccaggc tcggcccgcg caggtcgagc
    25621 aggtaggaga gccggttggc ggcgacgctg gaggctccgc cgagcagcga ataggcgtcc
    25681 gccgagggcg agttcgcgag ggcgtcgcgg tagtccgagc tggagatgcc gatgaagacg
    25741 cccgtgggcg aaccggccag gccgtacgga tcgagacctg cgtcctcgac ggcctcccag
    25801 gcgacctcca gcatgagccg ctgctgcggg tcgagtttgg cggcctcgtg ctcgttgatg
    25861 ccgaagaagt cgaggtccag gccgccgatc ccggtgagga agccaccgag ggcggcccgg
    25921 tccgtgccgc cgttcccgcc gccccagcgg gcgaaccggt cgtcgggtac ccgcccgatg
    25981 gcgtccccgc cccgttcgag cagctcccag aaggcctccg ggccgtccgc tccggggaac
    26041 ctgcacccca tgccgatgat cgcgaccggt tcgtccgggg tcgttcccgt ggccgcgcgc
    26101 tggggcgcgg cggtcgcgcc ccgctcgggc cgcccgtccc gcaggtgctc caggatctcc
    26161 cggagcgtcg ggtactcgta cgcgatcgtc ggtgagacct tgcggtccag gagcgcgccg
    26221 agctctcccg cgagcgcgac cgcgtcgatc gaggacaggc cgtaggcggc cagtggttcg
    26281 tggaccgaga tgtcctcgcc cgaaccgaga cgggccagct cggcgatgcg ccggcgcagc
    26341 caggtttcca gctccgtgtc caacatgtgc tccccctgtg ttctgctgtg gttcgagtca
    26401 gcgctgcgcg ttccacggag accggccggt caggtactcc ttccgggtct ccccgcgctg
    26461 cagcttcccg ctcgacgtct tgggaagggt tccggcggga aggaggacca cgtcgcgtgc
    26521 ggtcagccgg tgttcctggg ccacggcgtg ccgtaccgcg ttcgccacgg cctccgactc
    26581 cgagcggtcc tcgccggcgg cggcccccgg ccggagttcg gccgcgacca ccacgctctc
    26641 ctccccgtcc gtggtcacgc cgaaggcggc cacgcagccg ggccggatcg cggagtgcgc
    26701 gctctcggcg gtccgctcga tgtcgtgggg gtagtggttg cgtccgccga cgatgatgac
    26761 gtccttgatg cggccgcaga cgaacaggcc gtcctcggtc cggaagccga ggtcccccgt
    26821 gcgcatgtac gggccctgtc cgccgtcgct cggcgtggcc tcgaacgcct cccggctgag
    26881 gtcgggccgc tgccagtagc ccacggcgac gctctcgccc gcgacccaga tctcgccgac
    26941 ctcgcccggg gcgcaccggg tgtgccgctt ggggtcgacg atggcgacgt ccagcgtccg
    27001 gctgatgccg cagctgacga ggacgcgcgc gttcggactg tcctgcggca cgatccgggc
    27061 gacgccctcc tcgagctcgc tctcgtcgaa ggaccggaag atccacggct gttcgatcgg
    27121 cgccccgctc accagcagcg tgctctcggc gagaccatag accggaataa tggtttccgg
    27181 acggaacccg caggaggcga aggccgcgga gaagcgcttc atcgattccg cgcgaacggg
    27241 ttcggcgcca ttggtggcga cggcccagga cgacagatcc agcgtcgcgc ggtcctcttc
    27301 ggacactttt cgggtgcaca ggtcgaacgc gaagttgggc gcggccgaca gggttccgcg
    27361 gtacttcgag attgcgcgca gccaccgcac cgggttctgc aggaatgcca cggtgggcat
    27421 cgaaacggaa tggatcccca gcatcgccgg cgcgacgatc atcgagatga gccccatgtc
    27481 gtgatagggc ggcagccacc ccacgacgac ggtcgaatgg tcgagtccga gcgatgtgcg
    27541 gatgaggtcg gtgttgtggg cgaggttccg gtgggtgacc atcacgccct tcggctgacc
    27601 ggtcgagccg gaggtgtact ggaggaacgc gagggaatcc ggatcggggg ccggggcgga
    27661 ccagcccgct ccgccggcgt ccggaatctc gtcgaccgcc agccaggcgg tttcctggag
    27721 ttccggaatc gagcgcgccg tggtctcgat ggccgcctgt atcgcggagg tggtcaaaat
    27781 ggccgcgggc tgggcgtcct cggcgatgcc ggccagccgg agcagccctc gcgcacgctg
    27841 cgcggggtgc ggcaggtagg cggggacggc gacgacgccg gcgtacaggc agccgaagta
    27901 cgcgacgacg aagtcctggc cgggcatgaa cagcagcagg gcccgggaac cgggctccac
    27961 ctgcgcacgg aggcttgcgg ccacggcccg cgcccgggtg tcgagcatcg agaaggtgag
    28021 tgagggttcg gcctcgtcgc cgtcgggcag gaaggtgaac agatcgtgat ccgggatgcg
    28081 cgcagcgtgt gcgtgcagtg cgtcgaccac cgtttcgaag cggacctcgt ccagggcggt
    28141 gggggacagc gcgaatgact cgtcaagcat tctcagcctc attcagtgcc gatcggatgc
    28201 tcgcaccggg tgcgggccgg caggcaaatg gcgaaagcgg cgcgcggctc cacgagcgcg
    28261 ctccgcgcga gatgcccgtt cccggggata ccggagcacg ggatgccgga gctccagggc
    28321 tcacggcgac agcggtctgt acggagccgc ggatctgcgg acagggtggt gcgctgctct
    28381 ccggggcgaa tgacccgagg tcacgcaacc ggcgtcaatc gcatcctgat ccgcaaacat
    28441 caaccttgtc ttccggtgag tttcgatccg cagcacagcg cggacgcgga gaaggattga
    28501 ttcattccgc atgcgtccgg tcgttctgcg agcgcgttcc atgttcgtgc ggccccgaga
    28561 ggggcgccgg ctatcgcgcc ggggcgatag cgcctgcaac ttggtgggct tggcggaggt
    28621 acagacggaa acagccaaag gctggaagag gggttctggg cagtactggt ccaaacctta
    28681 gggcgggccc ctggattcgg tcaactcgcg cttaatggcc ggaagttgac tgcgaatgca
    28741 agaagacgag ggaattttcg gccaacctcc ggccggtgcg gacggcgctc gggagggggt
    28801 gccgcggctc cgagcggggc ggacgacaag ggggcccggt gaccgtagtt gatgcttgct
    28861 gagcgaaact gatcgtttcc ctggcgggta tcccgccatt cgggcaagcc attcgctcgc
    28921 tcccgagaag cccgggagcg ccccgacgaa gatgggagaa ccggccgtga ccggtatcga
    28981 gttcctcgcc tcgttcctca ggaccggacg actgcacggg atcggcatcg gctccaccct
    29041 cggcgaggtg gaccgggccg tccgccaccg cttcgtcgac gtggtcgacg aggacggccg
    29101 gtcgctgcgc cgcgactacg gattcgtcga gttctacttc aacgccggga acgagtgggt
    29161 gatgtccggc ggctccatcg aactgcaccg gctcgcgtcc ggccggtaca gggcgaagga
    29221 atgggcccgg accatggaga tcgcgttccc ccgccatgtc gcctggcggg acctgcgcga
    29281 cgaactcgcg cgcatccccg gagccccgga gctcacggtc ggtgaccagg gcggtttcct
    29341 cgagtaccgg gcttcggcgt ccggcgtctc ggtcctcgtc gtggacgacg aggaggagga
    29401 gcggggctgc cacgcggggc acggggacgt gtggagcgtc agcctgtggg cgcccgtacg
    29461 ggcgaggtga ccgcccggcc gtcgccctgc tgctcctggc cctgctgaag aactccgaac
    29521 gcagggccga acacgcgatc cagcgcaagc tcgacgcgat cgccgccgcc ctcctggagc
    29581 agttcgacgg cgagccgggc cgcgcgcacc aggagctggt caaggccatc gggatcgagg
    29641 acggcgagta gcgcagccgc cccgggggcg ccctgccccc ttgggccgag cggaccccgg
    29701 aacgggcgct ttcgagtgac ccgccgcgcg ggcctcggcc acgggcggcc cgaactcccc
    29761 gaccatctca ggcggccggt catgttccgg ccacgggccg ccgaccaggc cgggcaccgc
    29821 gcgcacgcgg ctccgggccg cgccgctggg agatcacttg tacgtcctgc tcgtggcgag
    29881 cgcgttcaac agcctcacgc agcgagtcca cgccgagctg cgcgaccacg gccaccgcgt
    29941 cgcggtcgaa ctcgccctgc ccggcgcccc cctgggcgac gccgtacgcg ctcaccaccc
    30001 cgacctcgtc atcgccccga tgctccgcac cgccatcccc gaggagatct gggccgaccg
    30061 cacctgcctg gtcgtccacc ccggaccggt cggcgaccgc ggtccctcct ccctcgaccg
    30121 cgccatccag gacggcgagc cccgatgggg ggtgaccgtc ctccaggcca acgcggagat
    30181 ggacgccggc gacgtctggg cgagcgtcga gtgccccgta ccgcccgtcg gcaagagcga
    30241 cctctaccgc ggcgagatcg ccgacgccgc gctggaggcc gtcctgctcg cggtggaacg
    30301 cttcgcctcc ggtacgtaca ccccgcagcc gcaggccgcc ggccgggccc ggccgctgct
    30361 gcgccaggag gagcgacgga tcgactggga gcgcgatggc accgcggacg tcctgcgcgc
    30421 gctgcgcgcc gcggactcgc agcccggcgt acaggacgag ctgctcggcg gcgagtggtt
    30481 cctgcacggc gggcaccgcg aggagcggct gcgcgggtgc cccggcgagc tgctggccac
    30541 ccggaccggg gccgtctgcc gggccacggc ggacggcgcc gtctggatcc cggaactgcg
    30601 cgcccgccgc ctcccgggcg gcccggtcgc cgccaagctg cccgcgacgc tggcactcgc
    30661 ggaccggctg ccaccgcttc ccgaggtccc cgcgccgccg gacagcggcc cgcaccgccg
    30721 cacctggtcg gacatcggct accacgagga cggacaggcc ggtttcctgt cgttctcctt
    30781 ccccggcggc gcgatgagca ccgcgcactg ccgccgtctg ctggacgcct accggaccgc
    30841 ctgtacccgc cccacgaccg tcctggtcct cggcggcggc cgcgacttct tctccaacgg
    30901 catccacctc ggtgtcatcg aggccgcgga cgacccggcc gaggaatcct gggccaacat
    30961 caacgccatc aacgacctgg tcgaggcggt gctgaccacc accgaccggc tcgtggtcag
    31021 cgcgctgggc ggcaacgccg ccgccggcgg ggccatgctc gccctcgccg ccgacgaggt
    31081 ctggtgccgc tcgggcgtcg tcctgaaccc gcactaccgc ctgatggggc tgcacggctc
    31141 cgagtactgg acgtacaccc tgccgcgccg cgtcggcccc tccctcgcgg aacgcctcac
    31201 cgccgaggcc ctcccgctga gcgcagccgc cgcgcacggg ctcggactgg tcgaccgtac
    31261 gctcccctgc ccgcccgggg agttcaccgc cgagacggag cgcctcgcgg tgcgcctcgc
    31321 cgggctgccc gccaccgcct cccggatcgc cgggaagaag gcggcgcgcg agcgcgacga
    31381 ggccctgcgg ccgctcgccg cccaccgcga ggccgagctg gccctgatgc ggcggacctt
    31441 cttcgacccg gacgccccct accacgccct gcgccgcgcc ttcgtccgca aggaacgccc
    31501 tgcggccacc ccgccccacc tccgggggcc gggataggcc ccgcggcacc gcggccgtcc
    31561 gtccgcccgg tgtcactgga ctggccgtac ctgacgcggc acccgggccg gactgctgtt
    31621 agcaagaaag gtgtgggtga ggcaggccgc ctctccccac cccctcccga tcccctcccc
    31681 gaggagccgt cccatggcca cagcgacgca ggaaaaggtt gaggatccgc tgatccacat
    31741 cctctggatc aacgcggggc tgagctgcga cggcgactcc gtgtccctga cggcagcgat
    31801 gcagccgagc atcgaggaga tcgtcaccgg tgtactgccc ggtcttccga agatcgccgt
    31861 gcactggccg ctgatcgact tcgaatgcgg cccggtcggc ggcgccgaca ccttcatcga
    31921 atggttcttc aagggcgagc ggggcgagat cgatcccttc gtcctggtgg tcgaggggtc
    31981 catccccaac gagaagatca agcccgaggg ctactggtgc ggcttcggtg acgacccgga
    32041 gaccggtcag cccatcacca ccagcgagtg gatcgaccgg ctggccccca aggccctcgc
    32101 cgtcgtggcc atcggcacct gcgccacgta cggcggtatc cacgcgatgg agggcaaccc
    32161 gacgggcgcc atgggcgtgc ccgactacct gggctgggac tggacctcaa aggccggcat
    32221 cccgatcgtc tgcgtaccgg gctgcccgat ccagccggac aacttctcgg agaccctgac
    32281 ctacctgctc taccaggcgg ccggctccgc cccgatgatc cccctcgacg acaagctgcg
    32341 tccgacctgg ctcttcgggg ccaccgtcca cgagggctgc gaccgggccg gctactacga
    32401 gcagggccag ttcgccgaga cctacgactc cccgctatgc ctggtcaagc tgggctgctg
    32461 gggccccgtc gtcaagtgca acgtgcccaa gcgcggctgg atgaacggca tcggcggctg
    32521 ccccaacgtc ggcggcatct gcatcgcctg caccatgccc ggcttccccg acaagttcat
    32581 gccgttcatg gacgaacctc ccggcgccaa ggtctccacg aaggcgagcg gcgcgtacgg
    32641 cgccctgatc cgccggctga ggtccgtcac cgcccacacg gtcgacgagg aaccgaagtg
    32701 gcggcagacc ggccgggccc tgaccacggg ctaccgcccg ccctggtgac gccccccgga
    32761 agcacacccc aactcccgct ctccgcaccg aagaagggtc acggcacaaa cgatgacacc
    32821 gaagacgaag gcggccgcag acggcagcgg tctggtggag atggcctggg atccgatcac
    32881 ccggatcgtg ggcagtctcg gcatccacac gaagatcgac ttcaagcaga agcgggtcgc
    32941 ggagtgctac agcacctcgt cggtcttccg cggctacagc gtcttcatgc gcggcaagga
    33001 cccccgcgac gcgcacttca tcaccagtcg catctgcggc atctgcggtg acaaccacgc
    33061 cacctgctcg gtgtacgcgc agaacatggc ctacggggtg aagccgcccc acctcgccga
    33121 gtggatcatc aacctgggcg agtccgcgga gtacatgttc gaccacaaca tcttccagga
    33181 gaacctggtc ggggtcgact actgcgagaa gatggtccgc gagaccaacc cgggggtcct
    33241 ggagctcgcc gagcgcaccc ccgccccgca cgccggcgag cacggctaca ggaccatcgc
    33301 cgacatcatg cgctccctca accccatcga gggcgagttc taccgcgagg cgctccaggt
    33361 ctcccgctac acgcgcgaga tgttctgcct gatggagggc cgccacgtgc acccctccac
    33421 cctctacccg ggcggcgtcg gcaccatcgc ctccgtccag ctcttcacgg actacatgag
    33481 ccgcctgatg cggtactgcg agttcatgaa gaaggtcgtc ccgctccacg acgacctgtt
    33541 cgacttcttc tacgaggccc tgcccggcta cgaggaggtc ggccgccgtc gcgtcctcct
    33601 cggctgctgg ggcgccctca acgaccccga gtactgcgac ttcacgtacg ccaacatgac
    33661 cgactgggga cggaagatgt tcgtcacccc gggcgtggtg gtggacggca agctcgtcac
    33721 caacgacctc accgagatca acctcggcat ccgcatcctg ctcggcagct cgtactacga
    33781 cgactgggag gggcaggagc agttcgtcac gcacgacccg ctcggcaacc cggtcgaccc
    33841 gcgccacccg tggaaccagc acaccatccc ggccccgcag aagcggaact tcgacgacaa
    33901 gtacagctgg gtcatgtcgc cccgctggtt cgacggcaag gaccacctgg ccctggacac
    33961 cggcggcggc cccatcgccc gcctgtggtc caccgcgctg tcggggctgg tccacaccga
    34021 ctacgtgcag gccaccggtc acagcgtcgt gatcaccctg ccgcgcacga tgaccaagcc
    34081 cgagacccgc ttcgagtgga agatcccgaa gtggagcaac gcgctcgaac gcaaccgcgc
    34141 gcgcacctac ttccaggcct acgcggccgc catcgccctg cactgcgccg agaagggcct
    34201 cgccgaggtc cgcgccgggc gcacccagac ctgggagaag ttcgaggtcc cggacgaggg
    34261 gctcggcgtc ggcttcaccg aggccgtacg cggcgtcctg tcgcaccaca tggtgatccg
    34321 cgacgggaag atcgccaact accaccccta cccgccgacc ccgtggaacg ccagcacccg
    34381 cgacaccttc ggcacgccag gaccgtacga ggacgccgtg cagaacaccc cgatcttcga
    34441 ggagaacacc ccggagaact tcaagggcat cgacatcatg cgcgccgtcc gcagcttcga
    34501 cccctgtctg ccctgcggag tccacatgta cgtgggcggc ggcaagacgg tcaagacgat
    34561 gcacgtgccc accggtctga gcggactggg cggatgaggg ccgcgatcga cggcccgcag
    34621 gccgggcgcc gggtcgagga ggtcctcgac cggctcgccg ccaccggcga ccgggcggcc
    34681 tgcgaggcgg ccgaggaact ggtgcgcgtc ctcatggact tctacggcgc cgggctcgcc
    34741 cggatcgtcg agaaggtcgg agaggcccct ctcaaggccg tccacgacga cgagctcgtc
    34801 gcgagcctgc tctccctgca cggcctgcac cccgaggacg tgcacacccg catcggccgc
    34861 gccctggccg cccacggcga accgctggaa ctgctcggct tcgacgagca caccggcatc
    34921 ctgcggctgc gcccctccgc cgcccccacc ggctgcggct gcggatccgg cggccaggac
    34981 ggcgccggcc gcaccctgga ggacagcctc gcctgcttcg cccccgaggt gaccggcgtg
    35041 gagcgggagc ccgccccggc cccggctccc gcactgctgc agatcggcac ccggcccccg
    35101 agcccggcac gggtgccgtg agcgggcccg gtctgcgtca cgacgccccg cgcgccccgc
    35161 gcgggctgcg ccggttcgcg ggtccgcgcc cgccccggcc cgagacctgc gaactgtgcg
    35221 gggtcgtcgt gccccccgac ggccaccgtc acctggtgca gaccgagcag cgcgcgctgg
    35281 tctgtgcctg caccgcctgc gccctgctct tcgaccggcc gggcgcgggc accggacgcc
    35341 tgcggaccgt accggaccgc tacctcaccg accccgggca ccggctcgac gacggcgcat
    35401 gggaactcct ccagatcccg gtcggcgtcg cgttcttctt ccgcaacgcc gccctcgacc
    35461 ggctggtcgc cctctacccg agcccggccg gagccaccga gagcgaactg gaccccgaga
    35521 cctggcagac cgtactgggc gccggccggc tgtcggagct cctcgaaccc gacgtcgagg
    35581 cgctgctgct gcgccgctcg gagggccgca ccgcgtgcta cctggtgccg atcgacatct
    35641 gctacgagct ggtggggcgg atgcggctgc tgtggcaggg cttcgacggc ggggcggagg
    35701 cccgggcagc cctggacacc ttcttcgagc aggtggaacg gcggtccagg gcgctggccg
    35761 agacgccggc gacgcccccg gcggcgacgg cggcgagggt ggaggacggg gtccgatgac
    35821 ggaattcgcc ttcacctgca ccggggtgcg cgccgacgcg tacgccgccg gccccaccct
    35881 cgtcttccgg ctgcggatca ccgcagccgg gggcgcccgg gtgcacgcca tcgccctgcg
    35941 ctgccagatc cgcatcgaac cggcccggcg cggctacgga cccgccgagg cggaaggcct
    36001 cgcggacctg ttcggcgagc gctcccggtg gggcaacacc ctccagcccg tgcagttcgc
    36061 ccaggtctcc gtcatggtcc cgagcttcac cggcgagacc gagaccgacc tcgtcgtgcc
    36121 ctgcacctac gacatggaca tcgcggcgac ccggtacttc caggccctgg cggagggcga
    36181 ggtgccgctg ctgatgctgt tctccggcac cgccttcacc ggggacgccg ggttccgcgt
    36241 cgagccggtg ccctgggacc gcgaagcctc gtaccggatg cccgtggccg tgtggcgcga
    36301 gatggtcgaa cagcacttcc ccggctgtgg ctggctccgg ctgccccgcg acaccatgga
    36361 cgagctgctg gccttccgct cccgccacgc gctcgcctcg tgggaggcga ccgtacggac
    36421 cctgttggac gcggccgccc cggcggagcc agcggccccg ccgggtcccg tccggctcgg
    36481 cgcgatcctg ccgcgcctca ccgagaggac ggcgccgtga ccacgacgac caccccgggc
    36541 tcccgcttcg ccgtcgcccg gcaggtggcg gacgcggtcc tcctggaggg gtacgtgctc
    36601 tacccctacc gggcctcggc cgccaagaac cggctgcgct ggcagttcgg cgtcctcgta
    36661 cccccggcgt ggggccacgc ccacgaggag cacgtcctcc agcagaccga gatcctgatg
    36721 gagccccggg gcgaggcgac cctcgccctc gaactgcgct tcctgcacgc gcagcggcgt
    36781 acggtccaac aggccgaggg cgacggggac ttcacggacg tccccgagct gcacctgacc
    36841 gaccgggtcc tgatgccctg ggacgagggc accgaggaac gggtcgaggt gagcgtgccc
    36901 gtcgccgaac tgctcggcga cgaaggcgtc accttcccgt tccgccgccc ggcccgtgtc
    36961 gacaccgagc ccgtggtcga tgccgacggc cgcacggtgg gccgcctggt gcggcgcacc
    37021 gcggagatcg aggggcggct gcgcctgcgc gctgtcgaac tccccggcgc ctaccgggtg
    37081 ttcagactcc gggccgtggt ggagaacacc agcccgtgga ccccgcccgc cggagccggt
    37141 cccctcgacc gggaggccgc actgccgcac tcgctggtcg ccgcccacct cctgctcggc
    37201 ctggactccg gatccttcct gtccatgacc gacccgcccg aatgggcccg gcaggcggtg
    37261 gccgcctgcg agaaccgcca cacctggccg gtgctcgcgg gcgaaccggg ccgcgccgac
    37321 gtggtcctgt cctccccgat catcctggag gaccacccgg ccatcgcccc cgagagcgcg
    37381 ggcgccatgt acgacgccac cgagatcgac gagatcctcg ccctgcgcac ggccgccctg
    37441 accgagcagg agaagcgcga ggcccgcggc accgacgccc gggccgccgc cgtgatcgac
    37501 ctcgccgact ccatgccccc cgaggtgctg gagcgactgc acggcgccgt gcgggccctg
    37561 cgggaggtca ccggcccgga gcagcccccg ctgctcacgg aactccccgc cgaggacgtg
    37621 gtgttcaggc ccgacacccc ctggtgggac ccggcccggg cggacaccgc ggacccggcc
    37681 cgcgaccgga tcgcgatcga cggcgcctcg gtgggacccg gcagccgcgt cctgctccgc
    37741 ccgggactgc ggcgcaccga cgcgcaggac ctgttcctcc agggccgtac cgcgctggtc
    37801 gaggccgtcc tgcacgacgt ggacggggga gtgcacctcg ccgtcaccgt ggaggacgac
    37861 ccgggcgcgg acatccgccg cgagcagggc aggttcctct acttccagcc cgacgaggtc
    37921 accccgctgg aggacgcgtg aacgcccggg tcctggtcgc cggcatcggc aacgtcttcc
    37981 tcggtgacga cggcttcggc gtcgagaccg tacgggcgct ggccgcgcac ccgctgcccg
    38041 aaggcgtcga ggtggtggac ttcggcgtcc gcggtgtcca cctcgcctac cagctcctcg
    38101 acggctacga caccctgctg ctggtcgacg ccaccgcacg cggcggcgag ccgggcacgc
    38161 tgtacctgat cgaggccgac gggagcgcgg gcccggaacc gggcggcgcc ggggcaccgt
    38221 caccgcccgt cctcgacggc caccacatgt cccccgacgc cgtcctcgcc ctgctggaca
    38281 ccctctgcgc cgggaccggc gccaccccgc cgcggcgcac cctcgtcctc ggctgcgaac
    38341 cggccggggt cgaggagggc atcggactga gcccaccggt ggccgccgcc gtaccggagg
    38401 ccgtacgcac ggccctggac ctgatccacg gccgggaccc cgacgaaacc gaccggcctc
    38461 gccgcgaact gaggagaacc ccatgaagaa ggccgtcatc ggcggggccg tggccgccgc
    38521 cctcgccgcc gtactgctgc agatgctccc cgacctccga cgctacctgc gcatgcgccg
    38581 gatgtgacac cgccggggcg cggccgtcga tgcggatgcg gatacgggcg cccgaatggc
    38641 gtacgggcgc gccgtccacc ggcgtgccga ccgcacggac tccgtcccgc cggttcaatg
    38701 agccccggca ggacggagtc cgatgcacga gatgtcgatc gccatggccg tcgtgggcca
    38761 ggtggaagag gcggcccggg cgggcggcgc gcacgccgtt acctccgtac ggctgcaggt
    38821 cggtgagctg gcgggggtgg tccccgacgc gctggccttc tgtttcgaac tggcctgcgc
    38881 cggaacggtc ctcgaaggag ccgaactcgt cacggagtcc gtgacggccc gcgcccgctg
    38941 cggttcctgc cccggcacct gggcggtggg catgcccccc gaactgtgct gccccggatg
    39001 cggcagggcc accgacgtgg aactgctgtc gggccgtgag ctggagatcc tcagcgtgcg
    39061 ctgggaagac ggccccgccg gtgcccctac ccgcgaaccg attcccgagg aggcctgaac
    39121 catgtgccga gtggtcgatc tgcggcaggc ggtgctcgcc aagaacgacg aagccgccca
    39181 ggtcctgcgc accgaactca ccgcccgcgg aacgacggtg gtcaacctgc tctccagtcc
    39241 cggcagcggc aagacggcgc tgctggagcg cgaactgctc ctcgcacggg agcggggcgt
    39301 ggccgtggcc gcgctgacgg cggacctggc caccgagaac gacgcgctgc ggctggcccg
    39361 ttcgggcgta ccggtcaagc aggtgctcac cgacgggctg tgccacttgg aggccgcgat
    39421 gctcggccgg cacctggacg gctggctgcc cggggacacc cggctgctct tcgtggagaa
    39481 cgtgggcaat ctggtctgcc cggccggcta cgacctgggg gaatcgctgc gggtggtgct
    39541 cgcctcggtg accgagggcg aggacaagcc gctgaagtac ccgaccgcct tcggcctggc
    39601 ccagctggtg gtggtcacga agaccgacat cgcgcgggcc gtcgagttcg acgaggccgc
    39661 cttccgcgcc aacgtcgagc aggtcaaccc cggtgtggag gtcgtcctca cctcggcgcg
    39721 ggcgggcgag ggactgggcg tcctgctcga ccgggcgctg gcggtcgggg cgggcggcgg
    39781 ggcgcacgcc ccggtgatgg cccgtcagca gcacgcagaa gcacacggac acggacacgg
    39841 acacggacac gcccacgcag acgcgcacgg gcacagtcac ggacatggcc acgaccacga
    39901 ccacgacgac gaccacgatc acgcccggga cgagggccac gatcacgatc acgacgggga
    39961 ccacgagcac ccgcacgtcc agaccgtcgc gcagacccgc tgatggaggc ggtgcagcgc
    40021 cgccgggtca ccgtccgggg cgtggtccag ggcgtgggct tccgccccta cgtctacacc
    40081 cgcgcgaccg ggctgggcct ggccgggcac gtcaccaaca cccccgaggg cgtcgtcgcc
    40141 gaggtcgagg gcgccccgga cgcggtctcg cggttctgcg aacggctcgc ggcggacgcg
    40201 cccccgctgg ccgtggtcga cgccgtcgac cactgggagg tccccgtcgc gggcggcgcc
    40261 ggattcacca tcatcgcctc ccggaccggc ggccccgccc ggacactcgt ctccccggac
    40321 gtggccacct gcgccgactg cctcgccgaa ctggccgacc cgaccgaccg gcgccaccgc
    40381 caccccttca tcacctgcac ccactgcggg ccgcgcttca ccatcgtcac cgggctgccg
    40441 tacgaccgtg cccacaccac catggccgcc ttccccctgt gccccgactg cgcccgcgag
    40501 tacgaggacc cggccgaccg ccgcttccac gcccagcccg tcgcctgccc ggcctgcggc
    40561 ccccgcctca ggctgctcac cggccgaccg ccccgcgaga gcgccggcgc cgacccggtc
    40621 gccgaggccc gccggctcct ggccgccggg gcgatcctcg ccgtcaaggg cctgggcgga
    40681 taccacctgg cctgcgacgc cacccacccg ggcgccgtgg ccgaactgcg ccggcgcaag
    40741 gcgcgcgggg acaagccgtt cgcgctgatg gcccgggacc tcgccgacgt cgagcggttc
    40801 gcgcacctcg gccccgagga acggcagctg ctcacgggtg gcgtacggcc catcgtgctg
    40861 ctgcgccgcc gcgcgggcac cgacggcccg gacggggtcg ccccgcgctg tcccgacctc
    40921 ggggtgatgc tcccgtacac cccggtgcac cacctgctgc tcggcctgcc cggcgacccc
    40981 ccgggacccc ggctgctcgt catgaccagc ggcaacctcg cgggggagcc catcgtcacc
    41041 gacgacgacg aggccctgga ccggctcgcc gccctggcgg acggctggct gacccacgac
    41101 cgccccatcc acgtgccgtg cgacgactcc gtggtgcggg tctgcgacgg cgagacgctg
    41161 accctgcggc gctcgcgcgg gtacgccccg ctgccgctga ccctgccggt accggtgccc
    41221 gcgaccctcg cggcgggcgg ggacctgaag aacgccttct gcctcggcga aggacgcaag
    41281 gcctggccgt ccgcccacat cggcgacatg gacgacctcg ccacccagca cgccctcgaa
    41341 cgcgccgagc ggcagctgga gtccatcacc ggcgtcaccc ccgtgctcct cgccgccgac
    41401 cggcaccccg gctaccgctc cgccggttgg gcccggcgcg ccgcgggcgc ccggcccctc
    41461 gtgcgcgtcc agcaccatca cgcgcacatc gcctcggcca tggcggagca cggcctgggc
    41521 gggggccgtc cggtgatcgg ggtcgccttc gacggcaccg gctacggcga cgacggcgcc
    41581 gtgtggggcg gtgaggtcct cctggccgac tacgccgggt acacccggtt cgcccacctc
    41641 gcctacgtcc cgctgccggg cggcgacgcg gccgtgcacc gcccgtaccg catggcgctg
    41701 tcccacctgc gggccgcggg catcgcgtgg acaccggacc tgccctgcac cgccgcctgc
    41761 ccgcccggag aactgcgggt gctggagcgg cagctggagc gcggcctgaa ctgcgtcccg
    41821 acctccagca tgggccgcct gttcgatgcc gtctcctccg tggccggcat ctgccaccgg
    41881 gccgggtacg aggcccaggc cgcgatcgag ctggaggggg cggcgtacgc agcgcacggc
    41941 gacggcggcg gccacggcga cggtgaggcc ggcggccacg gctacgcctt cggcctgtac
    42001 gtgccgccgg accccggcgg cggcccggtc accgccgatc cgtcgcccgt actggccgcc
    42061 gcggtggccg acgtacgcgc aggcacggcc ccggcgctga tcgccgcccg cttccatggc
    42121 gccgtcgcgg ccctcgtcac cacgctgtgc gagctcgcgc gcgagcggca cgggctggac
    42181 accgtcgccc tgaccggcgg ggtcttcgcc aacaccctgc tctcctcggc gtgcgcccgg
    42241 ccgctgcgcg cccgcggatt caccgtcctg cggcacggcc ggatcccccc gaacgacggc
    42301 gggctgtccc tgggccagct catggtggcc gccgcgcacc acaccccctg acctcaccac
    42361 agcaaggaga agcccatgtg cctggcggtg cccggcagag tgctcgacat cggggagaag
    42421 gacggcaccc gcatggccac cgtcgacttc ggcggtgtgc agaaggaggt gtgcctggag
    42481 tacctgccgg acctgcaggt gggggagtac gccatcgtcc acgtgggctt cgccctccag
    42541 cgcctcgacg aggagtcggc caagcagacc ctcgaactgt tcgctcaact cgggatgctg
    42601 caggaggagt tcggagaccc ctgggagcag gccgcggcgg ccggtggcga gccctggccc
    42661 ttcgccgacg aacccgaacc cgaaaccgca cccgagcccg tcctcgccgc gccgcaggag
    42721 gaagtccagc cgtgaagtac atcgaggagt tccaggaccc cgacctcgcc cgccggctgc
    42781 tcgacgacat ccacgccacg gtgacccgcc cctgggccct gatggaggtc tgcggcggcc
    42841 agacccacac gatcatccgg cacggcatcg atcaactgct tccggaacag gttgagttga
    42901 tccacggccc cggctgcccg gtgtgtgtca ccccgctgga ggtcatcgac aaggcgctgg
    42961 agatcgcctc ccgccccgat gtgatcttct gttccttcgg ggacatgctc cgggtgcccg
    43021 ggaccggccg tgacctgttc caggtgcgca gcgagggcgg cgacgtccgc gtcgtctact
    43081 ccccgctcga cgccctgcgg atcgcccagg agaacccggc gcgccaggtg gtgttcttcg
    43141 gcatcggctt cgagaccacc gcgccgccca atgccatgac ggtccaccag gcgaagaagc
    43201 tggggatccc caacttcagc ctgctcgtct cccacgtccg ggtgcccccg gcgatcgagg
    43261 cgatcatgca gtcgccgagc tgccgggtcc agggcttcct cgccgccgga cacgtgtgca
    43321 gtgtgatggg catgggcgag taccccgaac tggccgagcg ccaccgggtc cccatcgtgg
    43381 tgaccggctt cgagccgctg gacatcctgg aaggcgtacg ccgggccgtt cggcagctgg
    43441 agcgcggcga gcacaccgtc gacaacgcct acgcgcgcgc cgtccgtccc gagggaaacc
    43501 cggccgccct cgccatgctg gaggacgtct tcgaggtcac cgaccgggcc tggcgcggca
    43561 tcggggtcat ccccgacagc ggttggcggc tgtccgaccg ctaccgggac ttcgacgccg
    43621 aacaccgctt ctcggtcacc ggcatcaaca cccgggagcc ggccgagtgc cgcagcggcg
    43681 aggtgctcca ggggctgctg aaaccgcacg agtgcgaggc cttcggcacg ctgtgcaccc
    43741 cgcgcagccc gctcggcgcc accatggtct ccagcgaggg cgcctgcgcc gcgtactacc
    43801 tctaccggcg gctggagctg gggaccgtgc ccgcggccgc gcccgctgcg agcccggcga
    43861 ccgcgccccc tgcgaccgcc ccgacccccg tgagcgcccc gctggaggcg agccccgttg
    43921 tctgacaccg cactcgacat cacgggctgg acctgcccgg ccccgctgcg cgaccgcccc
    43981 cgcgtggtga tgggccacgg cggcggaggc gcactctccg ccgaactggt ccagcacctc
    44041 ttcgcccccg ccttcggcgg tgacgtactc gcccagctcg gggactccgc ggccgtctcc
    44101 ctcggcggcg tccgcctcgc gttctccacc gactcctacg tggtgcggcc gctgttcttc
    44161 cccggcggcg gcatcggcga cctcgccgtc aacggcacgg tcaacgacct ggccatgagc
    44221 ggcgccgaag cggcgtacct ctcctgcggg ttcatcctgg aggagggcgt cgagatgtcg
    44281 gtcgtggcgc gcgtggccga ggccatgggc gcggccgcgc gcgccgcggg cgtggaggtg
    44341 gcgaccggag acaccaaggt cgtggaagcg ggtcacgggg acggcatcta catcaacacc
    44401 gcgggcatcg gcgtcatccc cgacggggtg gacctgcgcc cgcagcgcgt cgtaccgggt
    44461 gacgtcgtca tcgtcagcgg cgagatcggg ctccacggag tggcgatcat gagcgtccgc
    44521 gaggggctcg aattcggggt ggacatccag agcgactgcg cggccctggg cggactcgtg
    44581 cggaccatgc tcgcggtcac gccggacctc catgtcctgc gcgaccccac ccggggcggg
    44641 ctggcggcgt cgctgaacga gatcgccgcc gcctcgggca ccggtgtcgt gatccacgag
    44701 ggccgcgtcc cggtgcccgc ggccgtcgcg aacgcctgcg cgatcctcgg actcgacccg
    44761 ctctacgtgg ccaacgaggg caagctggtc gccttcgtgc cccgcgagca cgccgacgcc
    44821 gtcctcgacg ccatgcgcgc gcatccgctg ggccgccacg cggcggtgat cggcgaggcc
    44881 gtcgacgccc acccgggcct ggtcgtggcc cgcaccggcc tcggcggcac ccgcgtggtc
    44941 gacctgccga tcggcgaaca actgccgcgc atctgctgac cggtccgcaa gatgggtgcc
    45001 ggccccgatg cgcggggccg gcgggacggg tggtgctcgg ggaggaacac cccctgcatc
    45061 ccttcggcgc cgacgtggag cggctggtgc ccccggcggt gatcccgctc ctgcgtcgtc
    45121 gcccgaccga cggaaaggag cggggccatg ccgcgatccg acgacacgag gaccaccggc
    45181 cccggtaccc ggcccgggta cggggatccc gtacggagcc ggagccggag ccggagccgg
    45241 aaccgaaggc gggcacgggc cccgggcgaa ccgcgcccgc accgccgcgc gtaccggcgg
    45301 gcgggcgcct ggctggccgt cgccctcggg atctgggccg cggtggccgg ggccaccctg
    45361 cccaacgggc tcgtactggc ggccgggctg gtcgtggccg cgctggcggt gaaccgcctg
    45421 ggcgcggcgg acccgcgcgc cggccgccgg gcgaagccga tggccccgcc ctgacagccg
    45481 gccgccccgc cgccgcccac cgctgcggct acggctacgg ctacggacgc ccggcggggt
    45541 cctggtcggg ggccggctcc tcagcggcct ccggggactt cgcgggggaa ggtacggccg
    45601 cgagcagcgg ggtgctcacg gcgcggcgct ccctgaacca cgcggccagc ggctcggtgt
    45661 agcgggcggt gagcgggccg atcaccacga ggatgagcac gtaggcggtg gccagcggcc
    45721 cgagggccgg ttcgatgccg gcggtgacgg cgagaccggc gatgacgatc gagaactcgc
    45781 cgcgggccac cagggtgccg ccggcccgcc agcggccgtt gatcccgacc ccggcgcgct
    45841 tcgcggccca gtacccggtg gcgatcttcg tgcccgcggt gaccagtgcg agcgcgagcg
    45901 cgggcagcag tacgggcgga atgctcgccg ggtcggtgtg caggccgaag aagacgaaga
    45961 acaccgcggc gaacaggtcc ctgagcgggc tgagcagggt gtgcgtcccc tcggccacct
    46021 cgccggacag ggcgatgccc accaggaacg cgccgaccgc ggcggacacc tgcaactgct
    46081 gcgcgatgcc cgcgaccagc agggtcagac cgaggacgac gagcagcagc ttctccgggt
    46141 cgtcgctgga gacgaaccga gagatgagcc ggccgtagcg gacggcgacg aacagcaccg
    46201 cacccgccac tccgagggcg atcgcgaggg tcaggctgcc cgccgcgaga ccgaccccgg
    46261 ccagcagcgc ggtgacgatc ggcaggtaga cggccatggc caggtcctcc aggaccagga
    46321 cgctgaggac caccggggtc tcacggttgc cgagccggcc caggtc
//
