LOCUS       NZ_BMVL01000004        22217 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence04, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000004
VERSION     NZ_BMVL01000004.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 640938)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 199200
            Orig. end                         :: 221417
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22217
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22217
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22217
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12217](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12217)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            431..2833
                     /gene="pucD"
                     /locus_tag="IE257_RS11980"
                     /old_locus_tag="GCM10010343_24700"
     CDS             431..2833
                     /EC_number="1.17.1.4"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pucD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267276.1"
                     /locus_tag="IE257_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24700"
                     /product="xanthine dehydrogenase subunit D"
                     /protein_id="WP_189967655.1"
                     /transl_table=11
                     /translation="MAQNTRTVPAGTPTNVTQKHNKGGIGESILRPDGTLKVTGEFAYS
                     SDMWHEDMLWGQTLRSTVAHAEIVSIDISEALAMPGVYSVLTYDDLPAEMKNYGLEIQD
                     TPVLAHGRVRHHGEPVALVAADHPETARRAAAKIKIDYRELPLVTDEASALAPDAPLIH
                     EGRDDHHIGHVPHPNIVHRQPIIRGNVEEARKRADVIVEGEYTFGMQDQAFLGPESGLA
                     VPSEDGGVELYVATQWLHSDLQQIAPVLGLPPEKVRMTLSGVGGAFGGREDISMQIHAC
                     LLALATNKPVKIVYNRFESFFGHVHRHPAKLYYEHGATKDGKLTHMKCKIVLDGGAYAS
                     ASPAVVGNASSLSVGPYVLEDVDIEAIALYTNNPPCGAMRGFGAVQACFAYEAQMDKLA
                     AKLGMDPVEFRQLNAMEMGTVMPTGQVVDAPAPVAELLRRVKARPLPPERQWESAGENA
                     DVRALPGGLSNTTHGEGVVRGVGYAVGIKNVGFSEGFDDYSTARVRLEVINGEPVAMVH
                     TAMAEVGQGGITVHTQIARTELGVTQVTIHPADTQVGSAGSTSASRQTYMTGGAVKNTC
                     EAVREALLEIGRRKNGSYHPAWATAELLLEGGKVVTDGGEVLADIADILENEAIDLELE
                     FRHAATEPFDLVTGQGNGHVQYTFAAHRAVVEVDTELGLVKVVELATAQDVGKALNMLS
                     VVGQIQGGTTQGLGVAIMEEIIVDPKTAKVRNPSFTDYLIPTILDTPTIPVDVLELADP
                     KAPYGLRGMGEAPTLSSTPAVIAAIRQATGLEINKTPIRPEALTGTL"
     gene            3155..4618
                     /locus_tag="IE257_RS11985"
                     /old_locus_tag="GCM10010343_24710"
     CDS             3155..4618
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125408.1"
                     /locus_tag="IE257_RS11985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24710"
                     /product="NCS2 family permease"
                     /protein_id="WP_189967657.1"
                     /transl_table=11
                     /translation="MTQSSVEPKTTAEEAGDGSQPPAGRSWLDRYFHITHRGSNIGNEV
                     RGGITTFMAMAYILLLNPLLLSGKDVAGTTMAASAIITATAFAAAVTTLLMGFVGKVPL
                     ALAAGLSVSGVLASQVAPQMTWPQAMGMCVVYGVVICLLVVTGLREMIMNAIPLALKHA
                     ITMGIGLFVALIGFVKAGFVGRGPEFGPPVQLGAVGELSGWPVMLFCVTLITIFMLQAR
                     KVPGAILIGIVGGTVLAAILNVIVDIDPKAWKSGPPELSGSAISKPDFSLFGDVSFGGW
                     GDVGYMTVGMIVFTLVLAGFFDAMATIIGVGTEAKLADDKGRMPGLSKALFIDGAGGAI
                     GGISGGSGQTVFVESATGVGEGARTGLASVVTGLFFAACLFFTPITQIVPGEVASAALV
                     VIGAMMMQNARHVDWSDSATSIPVFLTVVIMPYTYSITAGVAAGVISYVAIKIAQGKAR
                     EIGGFMWALTGIFLVFFALNPIEHWLGVG"
     misc_feature    4681..4696
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.12"
                     /tool="antismash"
     gene            4754..5905
                     /locus_tag="IE257_RS11990"
                     /old_locus_tag="GCM10010343_24720"
     CDS             4754..5905
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675793.1"
                     /locus_tag="IE257_RS11990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24720"
                     /product="XdhC family protein"
                     /protein_id="WP_189967659.1"
                     /transl_table=11
                     /translation="MLDIAEELNRWVEQGRDFAVATVVAVGGSAPRQPGAALAVDSEGT
                     AIGSVSGGCVEGAVYELCRQALEDGETVRERFGYSDDDAFAVGLTCGGIIDILVTPVRV
                     GSPAREVFAAGLAAAARGEAAAVARITQGPAELMGRAVFVRTEGAHQGGFGGHPELDRT
                     VAEEARAMLDAGRTGVLEIGADGRLCGEPLQVLVESSVPPPRMIVFGAIDFASALVRIG
                     KFLGYRVTVCDARPVFATKTRFPEADEIVVDWPHRYLETTDVDGRTVLCVLTHDAKFDV
                     PLLELALKLPVAYVGAMGSRRTHEDRNKRLREVGVTELELARLRSPIGLDLGARSPEET
                     ALSIAAEIVANRRGGSGAALTGAHIPIHPDVSRTTIDRIGSVA"
     gene            6048..7289
                     /locus_tag="IE257_RS11995"
                     /old_locus_tag="GCM10010343_24730"
     CDS             6048..7289
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031550.1"
                     /locus_tag="IE257_RS11995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24730"
                     /product="YncE family protein"
                     /protein_id="WP_189967661.1"
                     /transl_table=11
                     /translation="MLRTVRTLGLLAAAALLTAFTPAPTAPAPGGGLREVLFVGNNWEG
                     TADVLASTGDLAKVGRIDVVPDKAERLREIYLNPVKLAFFLGIRESAGEGHDQFVDDMY
                     TTPDGTAVVVSRPSFADVVSIDVTSGRINWRFPVSGYRSDHMAVSPDGTRVAVSASTSN
                     TVHVLDITTGRQVGSFGTGDKPHENTFTRDGRFLWNSSIGEVNTALDAPWLDWTKGDRK
                     ITVVDAQTFRTVRVIDMRERLDAFGRRDLSDAVRPVSFSPDESKLYFQVSFFNGFLEYD
                     VPSDRITRLKTLPANPATSPDRTTWVNDSRHHGMSMSPDGAKLCIAGTMDDFATVVDRA
                     TLAEGPLVPAAKPYWATVDGDGSACVISESGADRVTAIDFATGTKRVSVPVGDHPQRVR
                     LGHVPAGWTGPVGR"
     misc_feature    6051..6053
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7318..7785)
                     /locus_tag="IE257_RS12000"
                     /old_locus_tag="GCM10010343_24740"
     CDS             complement(7318..7785)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718707.1"
                     /locus_tag="IE257_RS12000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24740"
                     /product="OsmC family protein"
                     /protein_id="WP_189967663.1"
                     /transl_table=11
                     /translation="MARLHSYTTRVTWTGNLGTGTSHYRAYSRAHEVVAAELPAILGSA
                     DPTFRGDASRWNPEQLLLAALSQCHMLSYLHFCTINGVVVTSYVDEATGTMATAGDSGQ
                     FTEAVVHPRITVGDESMVAAAISLHEEAHRACFIANSVNFPVRHEPTVTVG"
     gene            complement(7971..8513)
                     /locus_tag="IE257_RS12005"
                     /old_locus_tag="GCM10010343_24750"
     CDS             complement(7971..8513)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677098.1"
                     /locus_tag="IE257_RS12005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24750"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189967665.1"
                     /transl_table=11
                     /translation="MIEGELVALRALRAEDAEHHLRWRNDPEVARWASAGDPCFGPVTR
                     EALTMLFERMLVLSPRESAVFTVETLPDRRVIGTVDYRDLDPWAGSATLGITIGEREFW
                     GRGHGSEAMRLLVDHLFGAFPLTRLQLDTWSGNERAVRAFTRLGFREEGRRRAAVLLAG
                     ERYDEVLFGMLREEWRA"
     gene            8697..9938
                     /locus_tag="IE257_RS12010"
                     /old_locus_tag="GCM10010343_24760"
     CDS             8697..9938
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743398.1"
                     /locus_tag="IE257_RS12010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24760"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189967666.1"
                     /transl_table=11
                     /translation="MVDIREVPESDIDRALELAYLVFHDRPEKEVRDKHHALLASCDRI
                     GAYDGAALVGFMAAHDFRLSVPGADLPCPGLTFVCVAPTHRRRGVLTALMTQMLRRTAA
                     AGSPIAALWASEAAIYGRFGYGSATTGATIEIDSTRPLALRIEPDRRPLRLLDPEEALA
                     VIGPFHEAARAGRAGRPTRSAERWREEWLAEQDEEDEELSPPRIIVLGGAGEPIAGYVL
                     YRTKPEDDAAAVRVPGRVRVDELEADTPAVAAALWECVASLDLTGKVSAWGRPLDDPLL
                     HFAADRDQVRVTAQFPALWVRLVDVRAALTARSWAAPVEVVLEVHDVRLPANAGRFRLK
                     AGPAGATYENDHADSATADLALDVRELAACYLGGTRIEELALAGLVQEHTPGAAAALDA
                     ALRTPVLPHTSDEF"
     gene            complement(10001..12217)
                     /locus_tag="IE257_RS12015"
                     /old_locus_tag="GCM10010343_24770"
     CDS             complement(10001..12217)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743400.1"
                     /locus_tag="IE257_RS12015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24770"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_189967668.1"
                     /sec_met_domain="T1TS (E-value: 1.9e-78, bitscore: 259.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFQLPDFYVPYPARLNPHLEDARTHTKQWARDFGMLEGSGVW
                     EESDLDSHDYALLCSYTHPDCDRDALALVTDWYVWVFFFDDHFLEMYKRSQDRDGAKEY
                     LDRLAAFMPMDLSGGFPEATNPVEAGLADLWARTVPAMSADWRERFSLSTKNLLNESMW
                     ELANINIGRVANPLEYIEMRRKVGGAPWSAGLIEYVSAEVPARVAHSRALGVLRDAFSD
                     AVHIRNDIFSYQREVADEGELSNAILVLETFLGCTTQEAAEASNDLLTSRLQQFEQTAL
                     VELPQLFADHALNPAEIAAVLAYAKGLQDWQSGGHEWHMVSSRYMNKEARPTAPTTLPF
                     LPSGLGTTALDLRSVFTKRSMELRHRSFTHVPFERTGPSVIPEIYMPHRLSLSPHLAHA
                     REESVAWSRRMGLLDPQPGDPGSAIWTEERLRGFDFAVCSAGIDPDATPEQLVLNACWL
                     TWGTYGDDYYPVVFAQSRNLPAAKATTARLISMIPVDHAGQPEPVTAMERALGDLWVRT
                     SAGMSVEQRTEFRATLVSMLESWLWEVDNQVQNRIPDPVDYAEMRRHTFGSHLTMYLCR
                     LGHQGRGIPEEIYTSGTIRSLENAVADAACMINDIYSYQKEVEVEGEVHNYVLVTRNFF
                     DIDYPQALHICHELMTRRTEEFEHIVATQLPLLYDDWKLGAEAREALDAYVGELKDWHA
                     GILNWHEKIRRYRPEDLHPQPDLLSTRILGPGFGMSAARISLPA"
     misc_feature    12424..12433
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(12454..12469)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            complement(12461..16735)
                     /locus_tag="IE257_RS12020"
                     /old_locus_tag="GCM10010343_24780"
     CDS             complement(12461..16735)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024777.5"
                     /locus_tag="IE257_RS12020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_24780"
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="WP_189967670.1"
                     /transl_table=11
                     /translation="MLTIPLAGAAVIALGAGLLTGPPAYAAEERGHGPADTSWPTPPPP
                     PSSGASSAIGTAKARAKSDGKRVLIDSLTTASSQTFATPGGTLTTETSLAPERVKNPSG
                     KWQKVDATLQTTADGTVAPLAVPSRLAFSGGGTGPMATMTAADGKKLALKAPFSLPKPT
                     LNGDSALYPSVLPGVDLELTATTVGGWRQVLIVRTAEAAASPALQKLQFPVETDGLTVS
                     ADAAGNLKAADAQGNARFTAPTPVMWDSARSASTGGAGAGRTKSAGAFAKQAAPAEETP
                     LAPSIASSSDGPGEGATVKPIATTVDDRGIQLVPDTALLGQGTGPWYIDPGWAPSLNNA
                     NQAWAQVQEAYPDTNEFNGTQYGQDRPATGYCGYNVGNPPCDGIGRTRAYFQIGVDTRL
                     YGTEVLSARFEANVVSSSSPSTQTPMGLYSTNAIGNPTSWNRQPCDKNSHMGGCAKEAG
                     ITMSGSGGIAFDVKNLVKRAVQYRWPTITVGLAPDNESDKYYRQRFDNTPRIVVEYDIT
                     PTVSSPRTGPTPGFADTNTYAGCRTPGAANAWDNPGWVGTNNNITFTADTHSATGLQLW
                     TAFIYWDDDNAGKTDFKESGWNGSSGPVTVDAGQLIDGHQYGWHARNTDGFLTSADSEW
                     CFFRVDRTPPTATVASADFPASGTIGAHPKLVGQEGTFTLSGTDPAPATGTRTSGLACA
                     RWTTDPVKAAATGWKCTDPGVIKLTGGKADVKVTPPHWGTNYVYLQTQDNAGNMSQPFV
                     YSYYAPSNPDAGKPVFGDINNDRKPDVLLPDTAGNLRTIAGGQDPYGAPNAVVQAAPGA
                     TPNWNGVQISHRGSLGRKTVDDLFAHEPGKAELYLYSNDNSGRLDGQANAPITKPATCV
                     TPAGASIDCAAHGYGVTNWSKVTQIAALGSPTGDSGDTADKLPTTSLLFVENGRLWLGT
                     AGSLNALAPQAVLLSANDTKWAGYDLLTPGRAQGTDFPTLWARSKTDGTLHAFSVKGTA
                     QAPDLTGFTNPAAGLVSGTIDPKVYPRVGSEGDLTGDGIPDLWAVDTNQQLVAFNGVGT
                     ATPFPTATGVSTTPVTLGNLNLPKAQWKLTGRTGTTTPSAVGSFPATTTNVTFPAAENI
                     GGRSSSYAAFSNAGGSYASTTGPVIDTRKSFTISTWVKATELGGVVLSQDLGRNSSLLL
                     FPNHNKKVWQFSIANGDTNPWPYDETNEVNSAGTITLNTWQQLTAVYDENTGLMRLYVN
                     GTLAATGHHKASTSPAPVGPFHLGRFKDAGAYLDSSPFKGGISNLAVYPYAAPVTAPQA
                     TGPIHLTAPTGFCVDNDFDRLEDGNKIQLWGCTGGAPQQFQISNDGTIRNQGMCLNAAG
                     GGVVNGTLIELRTCDGSAGSQQFLPRADGGIYHPASGRCLDLGNYDTTPGRQLWLYDCH
                     AGPAQRWTVPTLGTAPLPIPTP"
     misc_feature    16882..16899
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.77"
                     /tool="antismash"
     misc_feature    complement(16884..16899)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.61"
                     /tool="antismash"
     misc_feature    complement(16945..16955)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    20742..20757
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.92"
                     /tool="antismash"
     misc_feature    complement(21191..21209)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.11"
                     /tool="antismash"
     misc_feature    21195..21213
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.2"
                     /tool="antismash"
ORIGIN
        1 gtcgcgacgt cgtgaccgtc gagggtctgg cggagttctc caagcagcgc gaggagcacg
       61 gccacggcgg tgcctgcggc accggcggcg gctgcggcag caagggcgtg tccctggacg
      121 cggccaagca gtggcaggcg cacggaccca acagcgagct ccgctcgcgg gccggcgact
      181 cgcagaccgg cgagggcgtg gagctctcca acatccagca ggcgttcatc gacgccggtg
      241 ccgtgcagtg cggtttctgc accccgggtc tgctcatcca ggcggacgcg ctgctggagg
      301 agaactcctc cccgtccgac caggacatcc gtgaggccct gtccggcaac ctctgccgct
      361 gcacgggcta cgagaagatc ctcgacgcgg tccgcctcgc ggccgcccgt cagtcagagg
      421 cggtctgacc atggctcaga acacccgcac cgtgcccgca ggtacgccga cgaacgtcac
      481 ccagaagcac aacaagggcg gcatcggcga gtccatcctc cgtccggacg gcaccctcaa
      541 ggtcaccggc gagttcgcgt actcctcgga catgtggcac gaggacatgc tgtggggcca
      601 gacgctgcgc agcaccgtcg cccacgccga gatcgtctcc atcgacatct ccgaggcgct
      661 cgccatgccc ggcgtgtact cggtgctgac gtacgacgac ctgccggccg agatgaagaa
      721 ctacggcctg gagatccagg acaccccggt cctcgcccac ggccgggtac ggcaccacgg
      781 tgagccggtc gccctcgtgg cggccgacca cccggagacc gcccgccgcg cggccgccaa
      841 gatcaagatc gactaccgcg agctgccgct cgtcaccgac gaggcctccg ccctcgctcc
      901 cgacgcgccg ctgatccacg agggccgcga cgaccaccac atcggtcacg tcccgcaccc
      961 gaacatcgtg caccgccagc cgatcatccg cggcaacgtg gaggaggccc gcaagcgcgc
     1021 cgacgtcatc gtcgagggcg agtacacctt cggcatgcag gaccaggcct tcctcggccc
     1081 ggagtccggc ctggccgtgc cgtccgagga cggcggtgtc gagctgtacg tcgccaccca
     1141 gtggctgcac tcggacctcc agcagatcgc cccggtcctg ggcctcccgc cggagaaggt
     1201 ccgcatgacg ctctcgggcg tcggcggtgc cttcggtggc cgcgaggaca tctcgatgca
     1261 gatccacgcc tgcctcctgg ccctggccac gaacaagccg gtcaagatcg tctacaaccg
     1321 gttcgagtcc ttcttcggtc acgtgcaccg tcacccggcg aagctctact acgagcacgg
     1381 cgccaccaag gacggcaagc tcacgcacat gaagtgcaag atcgtcctgg acggcggcgc
     1441 gtacgcgtcc gcctccccgg cggtcgtggg caacgcgtcc tccctctcgg tgggtcccta
     1501 cgtcctggag gacgtggaca tcgaggcgat cgcgctctac acgaacaacc cgccctgcgg
     1561 cgcgatgcgc ggcttcggcg ccgtccaggc ctgcttcgcc tacgaggccc agatggacaa
     1621 gctcgcggcg aagctgggca tggacccggt cgagttccgc cagctgaacg ccatggagat
     1681 gggcacggtc atgccgaccg gccaggtcgt ggacgccccg gcgcccgtcg ccgagctgct
     1741 gcgccgcgtc aaggcccgcc cgctgccgcc ggagcgccag tgggagagcg ccggcgagaa
     1801 cgcggacgtc cgcgcgctgc ccggcggtct gtcgaacacc acccacggtg agggcgtcgt
     1861 ccgcggcgtc ggctacgcgg tcggcatcaa gaacgtcggc ttctccgagg gcttcgacga
     1921 ctactcgacc gcccgcgtgc ggctcgaggt catcaacggc gagcccgtcg cgatggtcca
     1981 cacggccatg gcggaggtcg gccagggcgg tatcaccgtc cacacgcaga tcgcccgtac
     2041 cgagctgggc gtcacgcagg tgaccatcca cccggccgac acgcaggtcg gctccgccgg
     2101 ttccacgtcc gcctcccggc agacgtacat gaccggtggc gccgtgaaga acacctgtga
     2161 ggcggtccgc gaggccctcc tggagatcgg ccgccgcaag aacggctcgt accaccccgc
     2221 gtgggcgacg gccgagctgc tgctcgaagg cggcaaggtc gtcaccgacg gcggcgaggt
     2281 cctcgcggac atcgccgaca tcctggagaa cgaggccatc gacctcgaac tcgagttccg
     2341 gcacgcggcg accgagccct tcgacctggt caccggccag ggcaacggcc acgtccagta
     2401 caccttcgcc gcgcaccgcg cggtcgtcga ggtggacacc gagctcggcc tggtcaaggt
     2461 cgtcgagctg gcgaccgcgc aggacgtggg caaggccctc aacatgcttt ccgtggtcgg
     2521 ccagatccag ggtggtacca cccagggtct cggcgtcgcg atcatggaag agatcatcgt
     2581 ggacccgaag accgcgaagg tgcgcaaccc ctccttcacg gactacctga tcccgaccat
     2641 cctcgacacc ccgaccattc cggtcgacgt cctggagctc gccgacccga aggcccccta
     2701 cggcctgcgc ggtatgggcg aggccccgac cctctcgtcc accccggccg tcatcgcggc
     2761 gatccggcag gcgacgggtc tggagatcaa caagacgccg atccgtccgg aagccctcac
     2821 cgggaccctc taggacggcg tggtccgggg gccgcgaggc ccccggacct cctcagactc
     2881 ttcgggcggt gcgcatggga acgtcacact tcacggcgca ccgtccggag gaccaacgaa
     2941 gcaccgcacc gctcgcggtc ccttcacccg gcagtacccc tgcaagaacc cccgtagtac
     3001 cagcggtcac ccccgcacta cccgcagtac acgcagtgca cattcgcgtc gcctcgggcc
     3061 gtcaccccgg gtcgtgcagc caaacgcagc atcccaaatc ccgcatctcc aatctccaag
     3121 cgggtgcccc tttgaacctt gggagttagg caccatgacc caatcgtcag tagagcccaa
     3181 gaccaccgcg gaagaggccg gcgacggctc tcagccaccc gccggcaggt cctggctcga
     3241 ccggtacttt cacataacgc acagaggctc caacatcggc aatgaggttc gtggcggtat
     3301 cacgaccttc atggcgatgg cttacatcct tctgctcaac cccctgctcc tctcgggcaa
     3361 ggacgtcgcc ggtaccacga tggccgcttc ggcgatcatc accgccaccg cgttcgccgc
     3421 agccgtcacg acgctcctca tgggcttcgt cggcaaggtg ccgctcgccc ttgccgccgg
     3481 tctctccgtg tccggcgtgc tggcctcgca ggtggccccc cagatgacct ggccgcaggc
     3541 catgggcatg tgtgtggtct acggtgtcgt gatctgtctc ctggtcgtca ccggcctccg
     3601 cgagatgatc atgaacgcga tccccctcgc gctcaagcac gcgatcacca tgggcatcgg
     3661 cctcttcgtc gccctgatcg gcttcgtcaa ggccggtttc gtgggcaggg gtccggagtt
     3721 cggtcccccc gtccagctcg gtgcggtcgg tgagctgtcc ggctggcccg tcatgctctt
     3781 ctgcgtcacc ctgatcacca tcttcatgct ccaggcccgc aaggtgcccg gcgccatcct
     3841 gatcggcatc gtcggcggca ccgtcctggc cgcgatcctc aacgtcatcg tggacatcga
     3901 tccgaaggcc tggaagagcg gcccgccgga gctcagcggc tccgcaatct cgaagccgga
     3961 cttctcgctc ttcggcgacg tctccttcgg cggctggggc gacgtcggct acatgacggt
     4021 cggcatgatc gtcttcacgc tggtgctcgc cggcttcttc gacgccatgg ccaccatcat
     4081 cggtgtcggc accgaggcca agctggccga cgacaagggc cgcatgccgg gcctgtccaa
     4141 ggcgctgttc atcgacggcg ccggtggcgc catcggtggt atctcgggcg gctccggtca
     4201 gaccgtcttc gtcgagtccg cgaccggcgt cggcgagggt gcccgcacgg gtctcgcctc
     4261 cgtcgtcacc ggcctgttct tcgccgcctg cctcttcttc accccgatca cgcagatcgt
     4321 cccgggtgag gtcgcctccg cggccctggt cgtcatcggc gcgatgatga tgcagaacgc
     4381 ccgccacgtg gactggtccg acagcgcgac ctcgatcccg gtcttcctga ccgtcgtgat
     4441 catgccgtac acgtactcga tcacggccgg cgtcgccgcc ggtgtcatct cgtacgtggc
     4501 catcaagatc gctcagggca aggcccggga gatcggcggc ttcatgtggg cgctgaccgg
     4561 gatcttcctg gtgttcttcg ccctgaaccc gatcgagcac tggctcgggg tcggctgacc
     4621 cggaccgatc gggtcggtcc accgatgagg ccgacccgat cgacccggtc gacctgctgg
     4681 tcgatcggct tttcgagaac cgcacgctcc acgtatccga tactggaacc gaacctctcc
     4741 gaggaggccc cccatgctgg acatcgccga agagctgaac cggtgggtcg agcagggacg
     4801 tgacttcgcc gtcgccaccg tcgtggcggt cggcgggagc gcgccccggc agcccggtgc
     4861 cgcactcgcc gtcgacagcg agggcacggc catcggttcg gtttccggtg gatgcgtgga
     4921 gggtgcggtg tacgagctgt gccggcaggc gctggaggac ggcgagaccg tccgggagcg
     4981 cttcggctac agcgacgacg atgccttcgc cgtgggcctg acctgcggcg gaatcatcga
     5041 catcctggtc accccggtcc gtgtgggctc tcccgcccgc gaggtgttcg cggccggcct
     5101 ggccgccgcc gcccgcggcg aggccgcggc ggtggcccgg ataacgcagg gtccggccga
     5161 gctgatgggc cgcgccgtgt tcgtccgtac cgaaggcgcc caccagggcg gattcggcgg
     5221 acaccccgag ctggaccgca ccgtcgccga ggaggcccgc gccatgctcg acgccggccg
     5281 gaccggcgtg ctggagatcg gcgccgacgg ccggctctgc ggcgagcccc tgcaggtact
     5341 ggtcgagtcc agcgtcccgc ccccgcggat gatcgtcttc ggcgccatcg acttcgcctc
     5401 cgccctcgtg cggatcggca agttcctcgg ctaccgggtg acggtgtgcg acgcacggcc
     5461 cgtcttcgcg acgaagaccc gcttccccga ggcggacgag atcgtcgtgg actggcccca
     5521 ccgctacctg gagaccaccg acgtcgacgg ccggaccgtc ctgtgcgtgc tcacccacga
     5581 cgccaagttc gacgtcccgc tcctcgaact ggcgctcaag ctgcccgtcg cctacgtcgg
     5641 cgccatgggc tcccgccgca cccacgagga ccgcaacaag cgactgcgcg aggtcggcgt
     5701 caccgagctc gaactggccc ggctgcgctc cccgatcggc ctggacctcg gggctcgatc
     5761 cccggaggag accgcgctgt ccatcgccgc cgagatcgtc gcgaaccgcc gcggcggcag
     5821 cggcgcggcc ctgaccggcg cgcacatccc gatccacccg gacgtctcga gaacgacgat
     5881 cgaccggatc ggctccgtgg cttgactgcc tgaccggccg cccggccgcc gaagatgaga
     5941 aaagggcgcg acccgtaggg gttgcgccct ttcggcgtcc cccctatctt accggccggt
     6001 aagaggaggc accctctcca tcccttcccc gtagcggagt cgatcggatg ttacgaaccg
     6061 tgcgcaccct gggcctgctg gcagctgccg ccctgctcac cgcattcacg ccggccccga
     6121 ctgctcccgc cccgggcggc ggtctgcgcg aggtgctctt cgtagggaac aactgggagg
     6181 ggaccgccga cgtcctcgcc tccaccggcg acctcgccaa ggtgggccgg atcgacgtgg
     6241 tccccgacaa ggcggagcgg ctgcgcgaga tctacctcaa ccccgtgaag ctcgccttct
     6301 tcctcggcat ccgggagagc gccggtgagg ggcacgacca gttcgtcgac gacatgtaca
     6361 ccacccccga cggcaccgcc gtcgtcgtct cccgccccag cttcgccgac gtcgtgtcca
     6421 tcgacgtgac ctccggccgg atcaactggc gcttcccggt gtccggttac cgctccgacc
     6481 acatggccgt ctccccggac gggacccgcg tcgccgtgtc ggcctccacc tccaacaccg
     6541 tgcacgtcct ggacatcacc accgggcgcc aggtcggctc cttcggcacc ggcgacaagc
     6601 cgcacgagaa caccttcacc cgcgacggcc gcttcctgtg gaacagctcc atcggcgagg
     6661 tcaacacggc gttggacgcg ccctggctgg actggacgaa gggcgaccgc aagatcaccg
     6721 tggtcgacgc gcagaccttc cgcacggtgc gggtgatcga catgcgggag cggctggacg
     6781 ccttcggccg ccgcgacctg tccgacgccg tccgccccgt gtccttcagc cccgacgagt
     6841 cgaagctcta cttccaggtg tccttcttca acggcttcct ggaatacgac gtgccctccg
     6901 accggatcac ccgtctcaag accctcccgg cgaaccccgc caccagcccc gaccgcacca
     6961 cctgggtcaa cgactcccgc caccacggca tgtccatgag ccccgacggg gcgaagctct
     7021 gcatcgcggg caccatggac gacttcgcga ccgtcgtgga ccgggccacc ctcgccgaag
     7081 ggccgctcgt gcccgccgcc aagccgtact gggccacggt cgacggcgac ggcagcgcct
     7141 gcgtgatctc cgagagcggc gccgaccggg tcacggccat cgacttcgcc acgggcacca
     7201 agcgggtctc cgttcccgtc ggcgaccatc cccagcgcgt ccggctcggc catgtcccgg
     7261 cgggctggac cggtcccgtc gggcgctagg ccggcggcgt ggggcaggcc cggaaactca
     7321 gcccaccgtc acggtcggct cgtgccggac ggggaagttg accgagttgg cgatgaagca
     7381 ggcccggtgg gcctcctcgt gcagtgagat cgccgcggcc accatcgact cgtcgccgac
     7441 ggtgatccgg gggtgcacca cggcctccgt gaactgcccg ctgtccccgg cggtggccat
     7501 cgtcccggtc gcctcgtcga cgtacgaggt gaccaccacg ccgttgatgg tgcagaagtg
     7561 caggtaggag agcatgtggc actgggacag ggcggcgagc agcagttgct cggggttcca
     7621 gcgggaggcg tcaccgcgga acgtcgggtc ggcactgccg aggatcgccg gcagctctgc
     7681 ggcgaccacc tcgtgcgccc gtgagtaggc gcggtagtgg ctggtgccgg tgccgaggtt
     7741 tccggtccag gtcacgcggg tggtgtagga gtgcagtcgg gccatggcgg ctgctccctc
     7801 tctcgggtac ggaccgggcg ggcggacgcc cgggacgtgg cggcggcctg gtcgaaccgt
     7861 gccggacgtc gacctggatc gtacggccgt cgccacggcc gtgtcggccg cgccctccgc
     7921 gaggcgatcg aaggcaccgc cggcctccga cgggcgcacc gtcggcgggg tcaggcccgc
     7981 cactcctccc ggagcatccc gaacagcacc tcgtcgtacc gctcacccgc cagcagcacg
     8041 gcggcccgcc gccgcccctc ctcccggaag ccgagccggg tgaacgctcg tacggcccgc
     8101 tcgttcccgc tccaggtgtc gagctggagc cgggtgagcg ggaaggcgcc gaagaggtgg
     8161 tcgaccaaca gccgcatcgc ctcggagccg tgcccccggc cccagaactc ccgctcgccg
     8221 atggtgatcc cgagcgtggc cgatccggcc caggggtcca ggtcgcggta gtcgacggtg
     8281 ccgatcaccc ggcggtccgg caaggtctcc accgtgaaca ccgccgactc ccggggcgag
     8341 agcaccagca tccgctcgaa gagcatcgtc agcgcctccc gtgtgaccgg gccgaagcac
     8401 gggtccccgg cggacgccca acgggccacc tcggggtcat tgcgccagcg caggtggtgc
     8461 tccgcgtcct cggcgcgcag tgcgcgcagt gcgacgagtt ctccctcgat caagctctga
     8521 tcctcactcc gtgacgtccg gaggcacacg gtagccacag atgatcacgg aggcgacgga
     8581 atttcggaga caccggggcg gcacaccccg gcggccgacc gccggagcga ctgaaatcca
     8641 tgacctccgg cccttatggg atgaccggtc cgcgatgacc gattagtctc gcgatcatgg
     8701 tggacatccg cgaagtaccc gagtccgaca tcgaccgtgc tctggagctc gcgtacctgg
     8761 tcttccacga ccggcccgag aaggaggtcc gggacaagca ccacgcgctg ctcgcgagtt
     8821 gcgaccggat cggcgcctac gacggcgccg ccttggtcgg cttcatggcc gcgcacgact
     8881 tccggctctc ggtgcccggg gcggacctgc cctgccccgg gctcaccttc gtctgcgtcg
     8941 cccccaccca ccgcaggcgc ggcgtactca ccgcactgat gacgcagatg ctgcggcgga
     9001 cggccgccgc gggcagtccg atcgccgccc tctgggcctc cgaagccgcc atctacggcc
     9061 gcttcggcta cggcagcgcc accaccggag ccaccatcga gatcgactcc acccgcccgc
     9121 tggccctgcg catcgaaccg gaccggcggc cgctgcggct cctcgacccg gaggaggccc
     9181 tcgccgtgat cgggcccttc cacgaggccg cccgtgccgg gcgggccggc cgtcccaccc
     9241 gcagcgcgga gcggtggcgc gaggagtggc tcgccgaaca ggacgaggag gacgaggagc
     9301 tgagcccgcc gcggatcatc gtcctcgggg gagcgggcga gccgatcgcc ggatacgtgc
     9361 tctaccgcac caagccggag gacgacgccg cggccgtccg cgtgccgggc cgggtccggg
     9421 tcgacgagct ggaggccgac accccggcgg tcgccgccgc gctgtgggag tgcgtggctt
     9481 ccctcgacct caccggcaag gtctcggcgt ggggccgccc gctcgacgac ccgctgctgc
     9541 acttcgccgc ggaccgggac caggtacggg tcaccgccca gttcccggcg ctctgggtgc
     9601 gcctggtcga cgtacgcgcc gccctgacgg cgcgctcctg ggccgcgccg gtggaggtgg
     9661 tgctggaggt gcacgacgta cggctgcccg ccaacgccgg gcggttccgg ctcaaggcgg
     9721 ggccggccgg ggcgacgtac gagaacgacc acgcggactc cgccacggca gacctggccc
     9781 tggacgtacg ggaactggcc gcgtgctacc tcggcggaac ccggatcgag gagctcgccc
     9841 tggccggcct ggtccaggag cacacccccg gcgcggcggc ggccctggac gcggccctgc
     9901 gcacgccggt actgccgcac acgagcgacg agttctgagg tccggcggcg ggggcggtcg
     9961 gccggcgagc cggtcctgcc cccgccgcac ggcctcgggg tcaggcgggc agtgagatcc
    10021 gggcggccga catgccgaag cctgggccca ggatgcgggt ggacagcagg tcgggctgcg
    10081 ggtgcaggtc ctccgggcgg taacggcgga tcttctcgtg ccagttgagg atgccggcgt
    10141 gccagtcctt cagctcgccc acgtacgcgt ccagcgcctc ccgggcctcg gcgccgagct
    10201 tccagtcgtc gtagagcagc ggcagctggg tcgccacgat gtgctcgaac tcctcggtcc
    10261 gccgggtcat cagctcatgg cagatgtgca gggcctgcgg gtagtcgatg tcgaagaagt
    10321 tccgtgtgac caggacgtag ttgtggacct cgccctcgac ctccacctcc ttctggtagg
    10381 agtagatgtc gttgatcatg caggcggcgt ccgcgaccgc gttctccagt gagcggatgg
    10441 tcccggaggt gtagatctcc tcggggatcc cccggccctg gtgcccgagg cggcacaggt
    10501 acatcgtgag gtggctgccg aaggtgtggc ggcgcatctc cgcgtagtcc accgggtcag
    10561 ggatgcggtt ctggacctgg ttgtccacct cccacagcca gctctccagc atgctgacca
    10621 aggtggcccg gaactcggtg cgctgctcga cggacatgcc ggcgctggtg cgcacccaca
    10681 ggtcgccgag agcgcgctcc atcgcggtca ccggctcggg ctgtccggcg tggtcgaccg
    10741 ggatcatgga gatcaggcgg gcggtggtcg ccttggcggc cggaaggttc ctgctctggg
    10801 cgaagaccac cgggtagtag tcgtccccgt acgtgcccca ggtcagccag caggcgttga
    10861 gcaccagctg ctccggtgtg gcgtcggggt cgatccccgc cgagcagacg gcgaagtcga
    10921 agccgcgcag ccgctcctcg gtccagatgg ccgagccggg gtcgccgggc tgagggtcca
    10981 gcaggcccat ccgccgggac caggccaccg attcctcgcg cgcgtgcgcc aggtgcgggc
    11041 tgaggctgag ccggtgcggc atgtagatct cggggatgac ggaggggccg gtgcgttcga
    11101 agggcacgtg ggtgaaggag cggtggcgca gctccatcga gcgcttcgtg aacacggacc
    11161 gcaggtcgag cgcggtggtg ccgagcccgg acggcaggaa gggcagggtg gtcggggcgg
    11221 tgggccgggc ctccttgttc atgtaccggc tggagaccat gtgccactcg tggccgccgg
    11281 actgccagtc ctgcaggccc ttggcgtagg cgaggacggc cgcgatctcc gccgggttca
    11341 gcgcgtggtc ggcgaagagc tgggggagct cgacgagcgc ggtctgctcg aactgctgga
    11401 ggcgggaggt gagcaggtcg ttggaggcct cggcggcctc ctgggtggtg cagccgagga
    11461 aggtctccaa caccaggatg gcgttggaga gttcaccctc gtcggcgacc tcgcgttggt
    11521 aggagaagat gtcgttcctg atgtgcacgg cgtcggagaa cgcgtcgcgc aggacgccga
    11581 gcgcgcggga gtgcgcgacg cgcgcgggga cctcggcgga cacgtactcg atcaggccgg
    11641 ccgaccaggg ggcgccaccc accttgcggc gcatctcgat gtattcgagc gggttcgcga
    11701 cgcgcccgat gttgatgttg gcgagctccc acatggactc gttgaggagg ttcttcgtcg
    11761 acaaggagaa ccgttcccgc cagtcggcgg acatggcggg aacggtccgc gcccacaggt
    11821 ccgcgagtcc cgcctccacc gggttggtgg cctcggggaa cccgccggac aggtccatcg
    11881 gcatgaaggc ggcgagccgg tcgaggtact ccttggcgcc gtcgcggtcc tgcgagcgct
    11941 tgtacatctc caggaagtgg tcgtcgaaga agaacaccca cacgtaccag tcggtgacca
    12001 gcgccagggc gtcgcggtcg cagtcggggt gggtgtacga gcagagcagt gcgtagtcgt
    12061 gcgagtcgag gtcgctctcc tcccagacgc cggacccctc cagcatcccg aagtcgcgcg
    12121 cccactgctt ggtgtgggtc cgcgcgtcct ccaggtgggg gttcagtcgt gccggatagg
    12181 gaacatagaa atccggcagt tgaaacggct gcgtcacggc gggctcggcc tttcgtccat
    12241 gggtacggga gcccggtcgg cccggtcccc cgcacgagat cagcagtgcc ctacccctgg
    12301 tacgcatggg acaagggtga attcacttca tcaggtgacg aaccgcccgt tccgcgccgc
    12361 ggggccctgc cgggggctac ggggcggggg agggaacggc ggaggccgcc ttgccgggtg
    12421 cgggaaggcg gcctccgttc gtgcgatgtg cgatgtgcgg ttacggcgtg gggatcggga
    12481 gcggcgccgt gccgagggtg gggacggtcc agcgctgggc cgggccggcg tggcagtcgt
    12541 agagccagag ctgccttccg ggagtggtgt cgtagttgcc gaggtcgagg cagcgaccgg
    12601 aggcggggtg gtagatgcca ccgtcggccc ggggcaggaa ctgctggctg ccggcgctgc
    12661 cgtcacaggt gcggagctcg atgagagtgc cgttgacgac accgccgccg gcggcgttga
    12721 ggcacatgcc ctggttgcgg atggtgccgt cgttggagat ctggaactgc tggggggcgc
    12781 cgccggtgca gccccagagc tggatcttgt tgccgtcctc gaggcggtcg aagtcgttgt
    12841 ccacgcagaa gcccgtgggc gcggtcaggt ggatcggccc ggtcgcctgc ggggcggtga
    12901 cgggggcggc gtaggggtag acggcgaggt tgctgatgcc gcccttgaag ggggaggagt
    12961 cgaggtacgc accggcgtcc ttgaagcggc ccaggtggaa ggggccgacg ggggccgggc
    13021 tggtggacgc cttgtggtgg ccggtggccg caagggtgcc gttgacgtac aggcgcatga
    13081 ggccggtgtt ctcgtcgtag acggcggtca gctgctgcca ggtgttcagg gtgatggtgc
    13141 cggcgctgtt gacctcattg gtctcgtcgt acggccaggg gttcgtgtcg ccgttggcga
    13201 tggagaactg ccagaccttc ttgttgtggt tggggaagag cagcagcgag ctgttgcggc
    13261 ccagatcctg gctgaggacg actccgccga gttcggtggc cttgacccac gtgctgatgg
    13321 tgaagctctt gcgggtgtcg atgacggggc cggtggtgct ggcgtaagag ccgcccgcgt
    13381 tgctgaacgc cgcgtaggac gagctgcggc cgccgatgtt ctcggccgcg gggaaggtga
    13441 cgttggtcgt cgtggcgggg aagctgccga cggcgctcgg ggtggtcgtg ccggtccgac
    13501 cggtcagctt ccactgcgcc ttgggcaggt tgaggttgcc cagggtgacg ggggtcgtgc
    13561 tgacaccggt ggcggtcggg aagggcgtcg cggtgccgac gccgttgaag gcgacgagct
    13621 gctggttggt gtcgacggcc cacaggtcgg ggatgccgtc gccggtcagg tcgccctcgg
    13681 agccgacccg cgggtagacc ttcgggtcga tcgtgccgga gacgaggccc gcggccgggt
    13741 tggtgaagcc ggtgaggtcg ggcgcctggg ccgtgccctt gaccgagaag gcgtggagcg
    13801 tgccgtcggt cttggaacgg gcccacaggg tcgggaagtc ggtgccctgc gcgcggccgg
    13861 gggtgagcag gtcgtagccg gcccacttgg tgtcgttggc ggagaggagg acggcctgcg
    13921 gggcgagcgc gttgagcgag cccgcggtgc ccagccacag ccgtccgttc tcgacgaaca
    13981 gcagggacgt ggtgggcagc ttgtccgccg tgtcacccga gtccccggtg ggggaaccca
    14041 acgccgcgat ctgggtcacc ttggaccagt tggtgacgcc gtagccgtgg gccgcgcagt
    14101 cgatcgaggc gccggccggg gtcacgcagg tggccggctt cgtgatcggc gcgttggcct
    14161 gcccgtcgag gcggccgctg ttgtcgttgc tgtagaggta gagctcggcc ttgccgggct
    14221 catgggcgaa gaggtcgtcg acggtcttgc gtcccagact gccccggtgg ctgatctgga
    14281 caccgttcca gttgggggtg gcgccgggcg ccgcctggac gaccgcgttg ggcgcgccgt
    14341 acgggtcctg gccgcccgcg atcgtgcgaa ggttcccggc ggtgtcggga agcagcacgt
    14401 cgggcttgcg gtcgttgttg atgtcaccga acacgggctt gcccgcgtcg gggttggacg
    14461 gcgcgtagta gctgtagacg aacggctggg acatgttgcc cgcgttgtcc tgggtctgca
    14521 ggtagacgta gttggtgccc cagtgcggcg gggtgacctt gacgtcggcc ttgcccccgg
    14581 tcagcttgat cacgccgggg tcggtgcact tccagccggt ggcggccgcc ttgaccgggt
    14641 cggtggtcca gcgggcgcag gccaggccgg aggtgcgggt accggtcgcc ggggcggggt
    14701 cggtgccgct gagcgtgaag gtgccctcct ggccgacgag cttcgggtgc gccccgatgg
    14761 tgccggacgc ggggaagtcc gcggaggcga cggtggcggt cggcggggtg cggtcgacgc
    14821 ggaagaagca ccactcactg tcggcgctgg tcaggaagcc gtcggtgttg cgggcgtgcc
    14881 agccgtactg gtggccgtcg atcagctgac cggcatcgac ggtgacggga ccgctgctgc
    14941 cgttccaacc gctctccttg aagtcggtct tcccggcgtt gtcgtcgtcc cagtagatga
    15001 aggccgtcca cagctggagg ccggtggccg agtgggtgtc ggcggtgaag gtgatgttgt
    15061 tgttggtgcc gacccagccc ggattgtccc aggcgttggc ggctccgggg gtgcggcagc
    15121 ccgcgtaggt gttcgtgtcg gcgaaaccgg gcgtcgggcc ggtgcggggc gacgacacgg
    15181 tgggcgtgat gtcgtactcg acgacgatgc gcggggtgtt gtcgaaccgc tggcggtagt
    15241 acttgtcgga ctcgttgtcg ggagcgagac ccacggtgat ggtgggccac ctgtactgga
    15301 ccgccctctt cacgaggttc ttgacgtcga aggcaatgcc accggacccc gacatggtga
    15361 tgccggcttc cttcgcgcag ccgcccatgt gcgagttctt gtcgcagggc tgccggttcc
    15421 agctggtcgg gttgccgatg gcgttggtgg aatacagacc catcggggtc tgggtgctcg
    15481 ggctcgagga ggagaccacg ttcgcctcga accgtgcgct gaggacctcg gtgccgtaga
    15541 gccgggtgtc cacgccgatc tggaagtagg cgcgggtcct gccgatgccg tcgcacggcg
    15601 gattgcccac gttgtaaccg cagtagccgg tggcgggcct gtcctgcccg tactgcgtgc
    15661 cgttgaactc gttggtgtcc gggtacgcct cctggacctg ggcccacgcc tggttggcgt
    15721 tgttcaggct gggcgcccag cccggatcga tgtaccaggg gccggtgccc tgaccgagga
    15781 gcgcggtgtc agggacgagt tggatgccgc ggtcgtcgac ggtggtggcg atcggcttca
    15841 ccgtggcgcc ctcgccgggg ccgtcggagc tcgacgcgat cgagggggcc aggggggttt
    15901 cctcggccgg cgcggcctgc ttggcgaagg cgcccgccga cttcgtgcgg ccggcgccgg
    15961 cgccgccggt cgacgcggag cgggccgagt cccacatgac cggggtcggg gcggtgaagc
    16021 gggcgttgcc ctgggcgtcc gccgccttga ggttgccggc cgcgtcggca ctgaccgtca
    16081 ggccgtcggt ctcgacgggg aactggagct tctggagggc gggactggcg gcggcctcgg
    16141 cggtgcggac gatcagtacc tggcgccagc cgccgacggt ggtggcggtg agttcgaggt
    16201 ccacgcccgg cagaacggac gggtagaggg cgctgtcccc gttgagcgtc ggcttgggca
    16261 gcgagaaggg tgccttgagg gccagcttct tgccgtcggc ggccgtcatg gtggccatcg
    16321 gacccgttcc gccgccggag aaggcgaggc gggaggggac ggccagcggg gccaccgtgc
    16381 cgtcggcggt ggtctgcagg gttgcgtcga ctttctgcca ttttccggaa gggttcttca
    16441 cccgctccgg cgcgagcgag gtctctgtgg tgagcgtccc gcccggggtg gcgaaggtct
    16501 gtgaactggc cgtcgtcagc gagtcgatga ggacccgctt gccgtcgctc ttggcccggg
    16561 ccttcgcggt accgatcgcc gaggacgccc cggatgacgg cgggggcggg ggtgtgggcc
    16621 aggaggtgtc ggccgggccg tggccgcgct cctcggcggc gtacgcagga gggccggtca
    16681 gcagaccggc cccgagagcg attacggcgg cgccggccaa ggggatggtg agcatgccgg
    16741 gggagcggcg tctgccggac acccccgggc cggagtggct tgaaaggaat gcaggcctca
    16801 agtcggaggt cctcgctgtc agcggtaaat gaagagaagt caggggcaca gttccttccg
    16861 atctgcaaac ctgtcaacag tctgtgagaa acctgtgaag gtgcgatgtc cggttcatgt
    16921 cacgaatcgc catgttgtcc atgggtgaca ttgctcatgg cgggacattc ttaatatctc
    16981 cttagacttc ccaacgcccg ttccatagcg tgcacttggt ccggaccctc acgggccggc
    17041 cttttcctgt accggtttcc tggggggatc ctgttgtctc atcggagtcg ctttgccatg
    17101 cgctcagcgc gtggcagagc acgggtcgcg gttgttgccg cactcgccgt tctagtttcc
    17161 ggcctgggtc ttcccgcggt ccaggcggct gacaaaccgc caaaagtgtg ggtgccaccg
    17221 aagaccgccc tgcccggcgc gaagccggtc aaggggtcgg acgccaagtc ctcgaaggac
    17281 aaggcgccgg ccgccaagcc ctggaagccc gcgccgaagt cgaaggctcc ggtcgggacc
    17341 agccgggtcg aggtcggcgc ccgccccgag tcgaagcctg ccgccggagc ggggtcggtc
    17401 caggccggcg agttgcccgt ctgggtcgca cccgggaagg acgcaaaggc caaggccctg
    17461 ccgtccgggc ccgcgaacgc gccctcggct gccgggagcg gcagcctgag cgttgaggtg
    17521 aaggacgcgg ccaaggcgcg cgccgccgga gtgaacggtg cgctgatcac cctcaccgaa
    17581 cccgcgggcg ttgccgccac gggcaaggtc gaggtcggcc tggacgtgtc ggcgtgggcc
    17641 aacggcgccg gcgccaactg ggccgaccgt gcccgcctgg tgcagcttcc cgcgtgtgcc
    17701 ctgacgaccc cgggtgcggc cggttgcacc acccgtacgc ccgtcgcctc gcgccgggac
    17761 gcctccgggc gcctggtcgc cgaggtcgag gtggcgaaga acgcggcgac tcccagcatg
    17821 ctgctgaagt cgcagcaggg cgcgcaggcg gcgccttccg cggccccgca ggtcatggcc
    17881 gcccagggcg tggccctcgc cgtggagccg ggcccgtccg gcaacctcgg cgactactcg
    17941 gcgacgccgc tcctgccgtc ggcctcctgg caggccggcg cgaactcggc gaacttcacc
    18001 tacggctata cggccgagat cccgtcgacg atcgcgggcg cggcgccgag cgtcgtgctc
    18061 ggctacgact cctcctcgat cgacggccgt accgcgtcga ccaacgccca gtccggcctg
    18121 atcggtgagg gctgggactg gcaccccggc tcgatctccc gctcgtacaa gggctgcaag
    18181 gacgcgggca tcaaggactc gggcgacgag tgctgggccg gcgacatcct ctccctgtcg
    18241 atggcgggtc acgccgggca gatcgtccgc gacgacaaca cgtgcgtcta ccgcctgcag
    18301 ggcgacgacg gcacgaagat cgagcgcctg accggccagc gcaactccgc ctggaagggc
    18361 gagggtttcc gcgtcaccac gaccgacggc acgcagtact acttcggcgc caaccgcctc
    18421 ccgggcggtg acggcaccga cccggaggcc aagtccgtct ccacggtgcc ggtctacttc
    18481 aacagcggcc aggacaagtg cctcggtgcc gacactccgg ccaacggcac ccaccagcag
    18541 ctgggttggc agtggaacct cgacttcgtc gtggacccgc accagaacct gacctcctac
    18601 cgctacgagc aggaggacaa ccactacggg cgcggcggcg gccagaacaa cggcaacggc
    18661 acccccaccc tctaccagcg cgcctcctac ccgacctgga tcggctacgg ccagcgcctc
    18721 cccgaccaga tcgcggccaa gggcaaggcg aacaccgcag cccagatctg gctccgctcc
    18781 gcggaccgct gcttcgaagc gggcgacgcc tgtgacccca cgaagcgcaa gaccaacgcc
    18841 acggcctggg gcgacacccc ggtcgaccag gagtgcgcgg ccaccggcca gtgcctgaac
    18901 ctgtcgccga ccttcttcac caccaagcgg ctgacgaaga tcgacaccga ggtcctgggc
    18961 accggcggct accgcaacat cgactcctac gcgctcaagc agcgcttcga ggcgccgggt
    19021 gacgggacct cgccgtccct gtggctggag tccatccagc gcaccgccac caacgcccgg
    19081 tccccgctga ccgtgccgcc cgtgctgttc gagccgctgc agattcccaa ccgcgtcgac
    19141 ggcgtggtca agcgccccga cggcaccgag gccagtacct cccgctacaa ccggccgcgc
    19201 atccagacca tcaccaccga gaccggtggc cgcatcaacg tggtctacaa ggccccggag
    19261 tgctcgcggg tcaagggcac catgcccgcg gccgacgaca ccaacaccat ggcctgcatg
    19321 ccggtcaagt ggtacctgcc cggccagtcc tacccggacc cggtcaacga ctggttccac
    19381 aaggtcgtcg tcgagtccgt cacccagcag gacatggtcg ccggccaggt cagcacggtg
    19441 accaactacg agtacggcgg tggcatcgcc tggcaccgca acgactccga gttcgccgac
    19501 cccaagaccc gtacgtggga ccagttccgc ggcttcgcca cggtcaccac ccgtaccggc
    19561 agcggcaacg cgtccgaggc cccgcgcacc aagtcggtgg ccaccttcct gcgcggcatg
    19621 gacggcgacg tcctcgccaa cggcaccaag cgcagcgtga acgtcccgga cagccagggc
    19681 ggcaccatca aggacgagga cgtcctgtcg ggcttcgtcc gccagaccga gacctacgac
    19741 cgcgacggcg gcaccgtcgt cggcgacgag gtctccaccc cctggctcgg cgccgtcacc
    19801 gccacgcgcg cccagtccgg cggcatgccc gccatcacgg cccgcgcgct gaacaccggc
    19861 aaggtcacca gccgcgccaa gctcgcgagc ggcgcctggc gcaccaccga gcggacgtcg
    19921 acgtacgacg acaccctgtt ctcgcggccc ctccaggtcg acgacaaggg cgacgtctcc
    19981 cgcaccgacc agcgcatgtg caccaccttc gagtacgcca ccggccccgg cggcgcactc
    20041 tctcagctcg cttcccgcac cctgatcgtc tcgggtgcgt gcggtcagac cccgaacgcc
    20101 gccaacacgg taggtgacac gcgcacctac tacgacgaca aggcgtacgg tcagaccggc
    20161 gcgacggccg accagaccgg caccgaggtg ctggagaggt acgacggcgc gggcaagccg
    20221 gtctaccggc tcaacatgac ggccgcgtac gacctgtacg gccgtctgac caccagcacg
    20281 aacaaggtgc gcaaggacgc cgcccacccg gacggcgcgg tcaccaagac cgagtacagg
    20341 gcactgccca acgcactgcc ctacgaggtc acccacacca acccgctggg ctggaagacc
    20401 accaccaccc tcgacaccgg ccgttcgctg ccgatgaaga cgaccgacga gaacaaccac
    20461 gtggccgagc gcggctacga cgccctcggt cgtgtcacca ccatctggca gccggggcag
    20521 gaccggaccg tcgacccgcc ggtccgcaag ttctcgtacg ccatgaacgg cgccaacgcg
    20581 ccgaccaccg ttctgagcca ggcgctcatg aacgacaaca agtacatcaa cagctacacg
    20641 atctacgacg gcctcggccg cgtccgccag acccaggcgc acaccccgtc cggcgtcacc
    20701 ggacgcatgg tcaccgacgc gctcttcgac tcgcacggct ggcaggtcaa gaccagcgcg
    20761 ccgtactaca acgacgagaa ggctcccggc ggggcgctct tcctgcccaa cggcggggtc
    20821 aaccccgaca gcaagatccc gtcccagacc gtctcgatct tcgacggact cggccgtacc
    20881 accgcctccg tgttccagtc ctacgggacc gagcagtggc gctcgaagac ggagtacccg
    20941 ggcgccgacg aggtccgaaa catcccgccg gccggtggct acgccacggc taagatcacc
    21001 aacggcttga cgtcggtggt gcgccagtac aagggcaaca cgcccgcggg tgactacgac
    21061 gcgaccacgt acgtcagcaa cacccagggc aaggagctct cccgcaagga ctccgccggc
    21121 aacgagtgga cgttcgccta cgaccttctg ggccgcacgg tgaagaccac cgacccggac
    21181 tcgggcacgg cggagactgt ctacgacgac agcaagaatc tcgtcacggt caaggacgca
    21241 cgcggtaagc aggccacggc cgtcagcgac cttctcggcc gcacggtcgc aacgtacgag
    21301 ggcgcggcag tcgacccggc gaagcgggtc ggtgccttca cctacgacac caaggcgctc
    21361 ggcaagccgt cgaccagcac gcgcttcgtc ggcggagaat cgggcagcgc gtacatcacg
    21421 gaggtcaccg gctacgacag cggctaccgc ccgttcggca gcaaggtcac catccctgcc
    21481 gtcgagaagg agctgcaggg cacctacgag acgaagaact cctacgacaa gtacggccag
    21541 ctcaagacca cgggcctgcc ggccatcgcg aaggccggcc tggacgcgga gaccctgacc
    21601 tacgggacga actccgtcgg cagcttcacc tcgctcgacg gcaaaatcgg ctccgtgatg
    21661 acgccgtacg tcgtggacat gcgctacgac cccttcggca gggccatccg caccactctc
    21721 ggtgacaccg gccgacagat cgtctcgacc gtcgactacg acgaggccac gggccggccg
    21781 gtccggtcca ccctggacaa gcagaccgcg gccacggcga gcgtcgatgt cctcgactac
    21841 acctacaacc gggtcggcca gctgacctcg atcagcaaca cgcaggacgg cgccgcccgt
    21901 gacctgcagt gcttcacgac cgactacctc ggccggctga cgcaggcctg gaccgacacc
    21961 gggaccacca cgacggctcc ccagccgagc gtgcgcggca tcggcggctg ctccaacgcc
    22021 acggggccca aggtcgacgg gacgggcaag cccagtgtgg gcgggccggc gccgtactgg
    22081 cagcagtacg agtacgacaa gatcggcaac cgcaccaagc tggtgaagaa ggacgtcacg
    22141 ggcaacgcgg ccaaggacac gacggtcacc cagaccttcg gatccggccc caacaccccg
    22201 tccaccgacc cgaagac
//
