LOCUS       NZ_BMVL01000002        20906 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000002
VERSION     NZ_BMVL01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 840996)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 712674
            Orig. end                         :: 733580
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20906
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20906
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20906
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10906](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10906)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(735..1496)
                     /locus_tag="IE257_RS07570"
                     /old_locus_tag="GCM10010343_15600"
     CDS             complement(735..1496)
                     /EC_number="3.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523247.1"
                     /locus_tag="IE257_RS07570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15600"
                     /product="PIG-L deacetylase family protein"
                     /protein_id="WP_189965915.1"
                     /sec_met_domain="PIG-L (E-value: 1.5e-26, bitscore: 89.3,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQPDQQPALQPMPTDWTRALAVVAHPDDLEYGCAAAIADWTDG
                     GRKVVYLLATRGEAGIDSIAPDECGPLREAEQRASAAVVGVSEVEFLDYHDGAIEYGLG
                     LRRDIAAAIRRHRPELIVTLNHRDTWGGAQGGGYWNTPDHKAVGRAVLDAAGDAGNRWI
                     FPELIEQGLQPWNGVRWVAVAGSSTPTHAADAGPGLERSVKSLLEHKAYIEVLTDQDPE
                     EYVRTFLTGNAQQAAARFGGRPAVPFEVFPR"
     gene            1515..2333
                     /locus_tag="IE257_RS07575"
                     /old_locus_tag="GCM10010343_15610"
     CDS             1515..2333
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460969.1"
                     /locus_tag="IE257_RS07575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15610"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_189965917.1"
                     /transl_table=11
                     /translation="MDRHGQVVALLDATGIFFEPARTAFPGAEEVAWARAAELDPGAFG
                     PDGAWALDFRYFAISRPGGRWVLVDAGVGPARSPAAAWAPVPGRLPDALAAAGIARADV
                     EAVVLTHLHEDHAGWSSGDDGRPFFPAARYVVQRAEVAALHRADPVWDWTVAPLRASGQ
                     LHEVDGAHRLAPGITLLPTPGHTPGHQSVLVDQGEGARDVVVTGDVLVHAVQLGDPAVP
                     YSHERDRDTARASRRALLARARERGALLATAHLTRAFVEPPPETTAGRRP"
     gene            complement(2397..4139)
                     /locus_tag="IE257_RS07580"
                     /old_locus_tag="GCM10010343_15620"
     CDS             complement(2397..4139)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033679.1"
                     /locus_tag="IE257_RS07580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15620"
                     /product="DNRLRE domain-containing protein"
                     /protein_id="WP_189965919.1"
                     /transl_table=11
                     /translation="MSSAVSLALAGGLAVAGVAAGPATAAVAAPAVSAGGAGETPVGAQ
                     AWTRVSKKYPNHSYWNAAGDLRVGNEAGTEGLSRAYLRLDTTALAGATVSKATFRITNT
                     GAASCTGRPVELWSVGAVSAKTTWNNQPAKAVRLATVTDAKGREGCAAGDLEFDATALV
                     TEAAAKSRTSVTVGLFAANESDASAWKRFAPATAKLETTIGRPAPPVISSPEFPDASNG
                     APANTGKARTPGTFTFGTGGATNIEKIVYWSEFEPREVTVAPGASAVITPTGSGPHMLY
                     AYSVDKAGRRSDQAVYHFWALGNGGVRDAAGDLNGDGLRDLWTLDPDGRLRFSAGRADG
                     TFAAPVDGGASFAPGSRIAAGGDWGEDGYNDLLVLESVEGLGAKQLRLFPNNGLGSVRP
                     HDGIVLSVIEDDPAQGNDHWSDAQDIADAGDLNGDGEPDLLVKQGAKLWAYTGSRSGYL
                     DMNGAPVLVGDGGWDTVAVLVPGDTDGDGAADLWVRDDASGDLFAVKGAKDAAGQLDPR
                     SWGTALRVKIGSGFGRAAYPTLVSAGDFDRDGLVDLSAVGADGKAVWFRATATGIDATP
                     RPIG"
     gene            complement(4273..5583)
                     /locus_tag="IE257_RS07585"
                     /old_locus_tag="GCM10010343_15630"
     CDS             complement(4273..5583)
                     /NRPS_PKS="Domain: Abhydrolase_1 (50-215). E-value:
                     2.5e-17. Score: 55.2. Matches aSDomain:
                     nrpspksdomains_IE257_RS07585_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241855.1"
                     /locus_tag="IE257_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15630"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_189965921.1"
                     /sec_met_domain="PF00561 (E-value: 9.2e-16, bitscore: 53.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAHSYRQPGTVLTDHRFSVPLDHARPDGERIELYAREVVAAGK
                     DPETLPWLLYLEGGPGFGARRFIGRQAWLERALTEYRVLLLDQRGTGRSTPVNRQTLPL
                     RGTPDRQAEYLSHFRADSIVRDAETIRPGLTGGAPWTVLGQSFGGFCATRYLSTAPEGL
                     TAALITGGLPSLTATADEVYEAAYPRIERKNLAHYARYPMDVERARRIAAHLAQAPAEL
                     PGGHRLTVEGFQSLGILLGGGDGSHQLHYLLEDAFVPTPAGPALSDAFLESARGLLSFA
                     GHPLYALHHEAIYAQDPATPTAWAAERVRAGHPRFDADKALAGDEPLLFTGETIHPWHF
                     TTDPALAPLRETAELLAARTGWQPLYDPARLAANEVPVAAAVYHDDMYVDTAHSLETAR
                     SIRGLRTWVTDEFEHDGVRAGGPRVLDRLLSLARDEA"
     aSDomain        complement(4939..5433)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS07585_Abhydrolase_1.1"
                     /evalue="2.50E-17"
                     /label="IE257_RS07585_Abhydrolase_1.1"
                     /locus_tag="IE257_RS07585"
                     /protein_end="215"
                     /protein_start="50"
                     /score="55.2"
                     /tool="antismash"
                     /translation="PWLLYLEGGPGFGARRFIGRQAWLERALTEYRVLLLDQRGTGRST
                     PVNRQTLPLRGTPDRQAEYLSHFRADSIVRDAETIRPGLTGGAPWTVLGQSFGGFCATR
                     YLSTAPEGLTAALITGGLPSLTATADEVYEAAYPRIERKNLAHYARYPMDVERARRIAA
                     HL"
     gene            complement(5729..6814)
                     /locus_tag="IE257_RS07590"
                     /old_locus_tag="GCM10010343_15640"
     CDS             complement(5729..6814)
                     /EC_number="1.1.1.306"
                     /GO_function="GO:0050607 - mycothiol-dependent formaldehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0010127 - mycothiol-dependent
                     detoxification [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (25-257). E-value: 1.5e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_IE257_RS07590_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267920.1"
                     /locus_tag="IE257_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15640"
                     /product="S-(hydroxymethyl)mycothiol dehydrogenase"
                     /protein_id="WP_189965923.1"
                     /sec_met_domain="ADH_N (E-value: 1.3e-28, bitscore: 94.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-30, bitscore:
                     101.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHRVRGVIARSKGAPVETTTILVPDPGPGEALVRVQACGVCHTD
                     LHYREGGINDEFPFLLGHEAAGIVESVGPDVTSVAPGDFVILNWRAVCGTCRACRRGRP
                     WYCFATHNATQPMTLEDGTPLSPALGIGAFAEKTLVAAGQCTKVDPAAAPAAAGLLGCG
                     VMAGLGAALNTGNVGRGDSVAVIGCGGVGNAAVAGARLAGASRIIAVDLDDRKLEWARG
                     LGATHTVNGRTDDVVKAIQGLTGGNGADVVIDAVGRPETYRQAFYARDLAGTVVLVGVP
                     TPEMKLELPLLDVFGRGGALKSSWYGDCLPERDFPLLIDLYLQGRLDLDAFVSETIPLD
                     GVEDAFARMERGEVLRSVVEF"
     CDS_motif       complement(5978..6010)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS07590_0002"
                     /evalue="1.00E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="IE257_RS07590"
                     /protein_end="279"
                     /protein_start="268"
                     /score="3.0"
                     /tool="antismash"
                     /translation="RDLAGTVVLVG"
     aSDomain        complement(6044..6739)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS07590_PKS_ER.1"
                     /evalue="1.50E-10"
                     /label="IE257_RS07590_PKS_ER.1"
                     /locus_tag="IE257_RS07590"
                     /protein_end="257"
                     /protein_start="25"
                     /score="32.6"
                     /tool="antismash"
                     /translation="DPGPGEALVRVQACGVCHTDLHYREGGINDEFPFLLGHEAAGIVE
                     SVGPDVTSVAPGDFVILNWRAVCGTCRACRRGRPWYCFATHNATQPMTLEDGTPLSPAL
                     GIGAFAEKTLVAAGQCTKVDPAAAPAAAGLLGCGVMAGLGAALNTGNVGRGDSVAVIGC
                     GGVGNAAVAGARLAGASRIIAVDLDDRKLEWARGLGATHTVNGRTDDVVKAIQGLTGGN
                     GADVVIDAVG"
     CDS_motif       complement(6596..6634)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS07590_0001"
                     /evalue="3.10E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="IE257_RS07590"
                     /protein_end="73"
                     /protein_start="60"
                     /score="10.6"
                     /tool="antismash"
                     /translation="LGHEAAGIVESVG"
     misc_feature    complement(6837..6850)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     gene            complement(6888..7826)
                     /locus_tag="IE257_RS07595"
                     /old_locus_tag="GCM10010343_15650"
     CDS             complement(6888..7826)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574497.1"
                     /locus_tag="IE257_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15650"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_189965925.1"
                     /transl_table=11
                     /translation="MLDVRRLRLLRELARRGTIVAVADALAFSPSAVSQQLTVLEREAG
                     LPLLERTGRRVRLTPAGQNLVRHAEAVLEQLEQAEADLAEARGGLAGALRIGTFPTATR
                     AIVPAALIALARRHPGLEPMVSETDPAAVAHALRAGDLDVALVHEYDFVPAEPEPGLAT
                     EPLYSEAMYLAAPADPASGRPGVPEPDQGAALRTHARAPWITATPGTLCHAMTVRACQA
                     AGFTPRVRHRVDEFATVLALVAAGQGVAVVPQLGVTGPDRPAVHLTRLLMQRRTNLAFR
                     SGAGAHPAVAAFGAALRAAVPPDLAGSRAVT"
     gene            7898..8869
                     /locus_tag="IE257_RS07600"
                     /old_locus_tag="GCM10010343_15660"
     CDS             7898..8869
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655585.1"
                     /locus_tag="IE257_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15660"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_189965927.1"
                     /transl_table=11
                     /translation="MAQDTADTADTADTATTATTATALPARPLQGIHVPLVTPFTRAGE
                     VAAEALEALAHEVLDAGATGIVALGTTAEAACLDEAERDLVTAVCARVCGERGAPLIVG
                     AGASGTRAAEASLALLARWPAVRAALVTVPAFVRPAAAGVLAHFARLAGASPVPLIVYH
                     VPYRTGQPLDAAALRALGSLPGVVGVKYAGGGIGEDAVALLGDLPAGFEVLAGDDVYLS
                     PLLALGAAGGILASAHLATGRFAELAGAWRAGDVAKARPLGHALARMSAAAFAEPNPAV
                     LKGVLHAQGRIPTPDVRLPLLPASEGAVKAVTAALEGLEGPV"
     misc_feature    9072..9086
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.02"
                     /tool="antismash"
     misc_feature    complement(9079..9093)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.99"
                     /tool="antismash"
     gene            9308..9982
                     /locus_tag="IE257_RS07605"
                     /old_locus_tag="GCM10010343_15670"
     CDS             9308..9982
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481378.1"
                     /locus_tag="IE257_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15670"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_189965929.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKHYRITRKLALAGTGGAALTLPLISATTAGAVETA
                     APMTYSVVAGDTLSEIAAQHSLSGGWQQLYDANKTVVGDNPSVIRPGIKLTIGKQAKAA
                     AAAKTAAVKPATAYPNNLDGWIRESLDVMAKHGIPGSYNGIHRNVMRESSGNPLAINNW
                     DINARNGIPSKGLLQVIDPTFRAYHVPGTAQDSYDPVANITAACNYAAARYGSIDNVNG
                     PY"
     gene            complement(10001..10906)
                     /locus_tag="IE257_RS07610"
                     /old_locus_tag="GCM10010343_15680"
     CDS             complement(10001..10906)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="IE257_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15680"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_189965931.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.7e-20, bitscore:
                     67.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.7e-13,
                     bitscore: 45.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSWRTTLTAAGVSGSRLRDDYTYAARRVLRREPAPYLALRMLAS
                     PPLVPCLAAGLAFMNLVDDVAETGTAAQRAAGLAALSERVEAALKSGDSPDPLLRAYAH
                     AVESRGLPPHWVSRFLAGAATAEAGFDGFEAEEDFQAYLDAYAWPGVLVFTGLQYRGGP
                     DPEQAAGWRRFVDAAQRVDFLADLCGDLADGRLCIPRARLADHAVTRADLEQARDTPAV
                     RALLAAECRRARTALDAARGILDLAEPGLRPVIATMTELMAHQLTAVERAGVAALRRDT
                     GYGLAAPLRILVRAARRRPV"
     gene            complement(10960..12678)
                     /locus_tag="IE257_RS07615"
                     /old_locus_tag="GCM10010343_15690"
     CDS             complement(10960..12678)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611345.1"
                     /locus_tag="IE257_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15690"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_209468333.1"
                     /sec_met_domain="Pkinase (E-value: 1.6e-48, bitscore:
                     160.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTSEAGRQLIDGRFELVAPLGSGGMGTVWRARDIALHREVALKE
                     VRPPDPATAAAQPGLADQLRERAVREARALARLAHPHVVTIHHIVEPPDGGDGHPWIVM
                     ELVQGGSLHDRLASGPMPPADVLRLGLDVLSALRAAHAEGVLHRDVKPANVLLRPSGSA
                     VLTDFGIAALHGSTGLTSTGVLIGSPEYIAPERVRGEEGLAASDLWSLGMLLYVAAEGV
                     HPLRRATSLATVVAVLDEPIPAPVRSGPLAPVLERLLVRDPAARPDGAQLEQLLRDASA
                     ALGSGYGAGAAPVVPAPPIVPAPLAAVTPVGGAPAVPGQFGPYGGPYGSPTPPPFGAGS
                     SPYGSTTTPVPLASAPRRRPALIGAALTVVLAAAVVGIVQSLPDGNSGDDDAVDARATR
                     PVAATPGGSPVLTPRPKASTSQAGTARGSMLTPQNIRTALAALKEKTGTTTFVDLKVYD
                     GYVLASIPTAPGAETVDAWQYRDGAAKRTGPDGTVEEGEPLIDMSTVNWDALPGLLEQS
                     KKELGVEKPTSTYVIVEPWMMDQVPCMRPYLSDEYGRGGYVLAGIDGKVKKVVGS"
     gene            complement(12706..14334)
                     /locus_tag="IE257_RS07620"
                     /old_locus_tag="GCM10010343_15700"
     CDS             complement(12706..14334)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040929.1"
                     /locus_tag="IE257_RS07620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15700"
                     /product="peptide-N4-asparagine amidase"
                     /protein_id="WP_189965933.1"
                     /transl_table=11
                     /translation="MRRRHRITGLLGAIALTAATLAAAAPAPAGTQPADPPPAEFGTDW
                     HDPLTATPPVTRPATRSCQVTLAEARFSDFTPYRGNYAPPTGCGADAWAKVVLRLEGKV
                     KGRQYDRLGHLSLGGVEILRTSTPQPSPDGITWSVEKDVTRYRDTLARPQPVEMLIGNV
                     VDDTYTGVIDVKVTLTFYAADGGTRAPDTPDRVLPLTSPAVTTPRNTERLLAEVYATGS
                     GGGCEEYWYMTTPDAAPYSCKATDGPHREVRVSVDGQLAGIAAPFPTVWTGGWSNPFLW
                     YVTPGPRAFDVQPIRYDLTPYAALLNDGRPHRIEVSVAGVPAGQSGWSTPTNLLLWQDE
                     AREVVTGALTRHEESDPSGHSRWTPAPPGAQHRLDTEGGHRLTVAGHLNTSRGRVATTV
                     TRSVRSTSVHRWTDGENQDGLTATWTDEESVTHGPTTTRTDRTYTMDGETTLGEGDRLR
                     TVLALGDRADTVTVRGGRTVDSVRLDDRYTGDATYTANVPRDQRHAVATTSARYRLYGS
                     TVLGGCYDRTVATVQGTLTVDRRRC"
     gene            complement(14447..14974)
                     /gene="rraA"
                     /locus_tag="IE257_RS07625"
                     /old_locus_tag="GCM10010343_15710"
     CDS             complement(14447..14974)
                     /GO_function="GO:0008428 - ribonuclease inhibitor activity
                     [Evidence IEA]"
                     /GO_process="GO:0051252 - regulation of RNA metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="rraA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004923778.1"
                     /locus_tag="IE257_RS07625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15710"
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="WP_372452956.1"
                     /transl_table=11
                     /translation="MDEPQFEYEQRGNRYPMSVTPVPTADLYDEYGESLAICTTGFRRF
                     GGRRLFAGPVRTVRCLEDNALLRPLVHTPGEGAVLVVDGGGSPRTALVGDLIAGAAEAH
                     GWAGLIINGSVRDSVALGGLDLGIKALGTVPRKSGKTGEGAVDEPVTIGDITFRTGDTV
                     HADDDGVVVLPR"
     gene            complement(15247..15513)
                     /locus_tag="IE257_RS07630"
                     /old_locus_tag="GCM10010343_15720"
     CDS             complement(15247..15513)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380038.1"
                     /locus_tag="IE257_RS07630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15720"
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="WP_030390536.1"
                     /transl_table=11
                     /translation="MGIVSWIILGLLAGGIAKVLLPGRDPGGLIGTTLIGVAGAFIGGW
                     LSAKVLDKPIQTEFFDLATWGSAIAGSLVLLIGYRILFGNSRD"
     gene            complement(15614..16516)
                     /locus_tag="IE257_RS07635"
                     /old_locus_tag="GCM10010343_15730"
     CDS             complement(15614..16516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955571.1"
                     /locus_tag="IE257_RS07635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15730"
                     /product="hypothetical protein"
                     /protein_id="WP_189965935.1"
                     /transl_table=11
                     /translation="MNDTTLAVGLCVASAVAYAAAAVAQERLARAAVARTAGALLGSGA
                     WWWSAGLNAAAALLHAAALRYGPLTLVQPLGALTLVAAVPLGARRSGRRVAATEWRGTL
                     ATVAGLGLLLLPASGPAPDDTLTLVEALAVSGATIAVIMMLTAVKDPRSGLRHATASGL
                     ASAAASALTQTVAVAAGRGGALLSVRVVSVALLVMVFAVGGMLLSQRAYRGGLGAPLAV
                     VNLANPLAAAAIGMVLLGERLQGGPAGLLLAATGALLAARGVMLLTRTPSAAAGPGVGT
                     AAGSVAGAELPVPVGRVAV"
     gene            complement(16513..17361)
                     /locus_tag="IE257_RS07640"
                     /old_locus_tag="GCM10010343_15740"
     CDS             complement(16513..17361)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122211.1"
                     /locus_tag="IE257_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15740"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_189965937.1"
                     /transl_table=11
                     /translation="MSSHTTPAESAAGPRAARRRLIRELLLVAGFFAVYKAGRLLSTDR
                     TEEAFRNAERIWDAERALHLPGEGLLQQLLLHGDALVTTANTYYAGVHFPATALFLIWL
                     YVRRPAHYLWTRRVLAALTAAALVLHLAFPLAPPRLLDATQLIDTAQVYGPSVYRAAPA
                     EDTLANQFAAMPSLHFGWALMLALGMIAATSSRWRLLWLLHPLLTLTVIVGTANHYWLD
                     AVVAAVLLGAALLLVPRPRDDAPDDEAGPDPEAARENDPDGPVRGLPRPRSADAAVGAG
                     Q"
     misc_feature    complement(17452..17463)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            17515..18147
                     /locus_tag="IE257_RS07645"
                     /old_locus_tag="GCM10010343_15750"
     CDS             17515..18147
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645239.1"
                     /locus_tag="IE257_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15750"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189965940.1"
                     /transl_table=11
                     /translation="MTSTPTPARRSKITPEREQEFYDAVLEQLREHGYEALTMEGVAAR
                     ASCSKSTLYRQWKTKPQLVAAALRAGRRGTLVAVDTGSLAGDLREAARIAAGTSGRDTR
                     LTQALGHAVLSDEELQAALREALVEPELAAFAEMVGRAVARGEIAADHPAVEFLPAQLM
                     GVLRIRPVLEGRYADADYLVRFVDAVILPSLGLAPSHPARPPAGQAP"
     gene            complement(18353..18895)
                     /locus_tag="IE257_RS07650"
                     /old_locus_tag="GCM10010343_15760"
     CDS             complement(18353..18895)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034869.1"
                     /locus_tag="IE257_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15760"
                     /product="TerD family protein"
                     /protein_id="WP_189965942.1"
                     /transl_table=11
                     /translation="MTGVRKGLAKVEFALRWDPSPAGAPANDLDIVAAVYGAADLHGTP
                     VQSVHFGSRSPDGTIALNRDSHTGQGFGFDEVMTIELHRMAQESSRVVVGVVIQNSDAG
                     PEGRTKTFADIAGTGFRIREGHTDLAEGDFAAVAAATAATVAEFTRDASGAWSFDLRLR
                     GSDADPDEFARTMGALG"
     misc_feature    complement(19120..19136)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.87"
                     /tool="antismash"
     misc_feature    19176..19193
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.57"
                     /tool="antismash"
     misc_feature    19188..19201
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.17"
                     /tool="antismash"
     misc_feature    19188..19202
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.38"
                     /tool="antismash"
     gene            19334..20152
                     /locus_tag="IE257_RS07655"
                     /old_locus_tag="GCM10010343_15770"
     CDS             19334..20152
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266962.1"
                     /locus_tag="IE257_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15770"
                     /product="glutamate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_189965944.1"
                     /transl_table=11
                     /translation="MKVPQAGAVAAVIAIALTASGCVGDEGDQGDGTLAIGIKFDQPGI
                     GMRETDGTFTGFDVDVATYVAKELGYKANKIEFKQVYSNDRELLLQYNEVKFVVASYSI
                     NEKRKEKVDFAGPYFVAHQDLLTRAGDASINKPEDLNSKSLCSVTGSTSAENLRKNLAP
                     KAGLLELGGYSDCVVALQDSRVDAMTTDNAILAGYAARKGNEGKFKLLGQNLSNENYGI
                     GVKKGNKDLQRKINDALKKMVADGSWETAVKKNFGSNYKYEPAPAVAPVG"
     gene            complement(20268..20834)
                     /locus_tag="IE257_RS07660"
                     /old_locus_tag="GCM10010343_15780"
     CDS             complement(20268..20834)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019066012.1"
                     /locus_tag="IE257_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_15780"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_189965946.1"
                     /transl_table=11
                     /translation="MAVKILIVTGDAAESLEVLYPYQRLREEGYEVHIAAPQVKKLRFV
                     VHDFEEGFDTYTEKPGYTWPADLAFVDVVTEDYAALVVPGGRAPEYLRNDPEVRRILAA
                     FAEADKPIAQICHGPLITAAAGGLTGRRVTAYPALELDMEAAGAEFEDAETVVDGTLVS
                     ARAWPDHSSWMREFLTVLRSKAPVV"
     misc_feature    complement(20814..20829)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.63"
                     /tool="antismash"
ORIGIN
        1 ggcccgttcg cggcgatctc ccgtgccacg gcgcgcgcgg aggactccag gtcctcgccg
       61 gggacgacca gctggaccag gttgaggcgc agcgccgtcg cggcgtcgat gcggcggccc
      121 gtcagggcca ggtacttggc ccagcccgca cccgcctcgc gggcgatgcg gaggtcacct
      181 cccgcgtcca ccgccacccc caggccggcc tccggcagcg cgaagacggc gtcctcggcc
      241 gccacccgga cgtcggccat cagcgccagc tcgaagccga agccgaggca gtagccctgg
      301 acggcggcca ccaccggctg cgggaggcgg gcgaggaccg cgaaccgctc gtgcacccag
      361 cggatgccct cgtagtagtt gcgggtgcgc gccgccgggg atccgcccgt gatggcgccc
      421 cccggggcgg tcacgtcgat gcccgcgcag aaggcccggc cctcggcccg cagcagcacc
      481 gcccgcacgg acgcgtcgaa gcggatccgg tccgcgagca ggccgagctg acgggtggac
      541 tcccagctcc agccgttgag tttgtccgga cggcacaggg tgaggaccgc gagaccgtcg
      601 gcgacctcca gccggatgcg ctcctcaccc tccgcgatct ccgtggagat ggtgtcgatc
      661 actgtgtccc gcacccccgg cccgatggct gacgacctga cgaactgacg aatcgtcaga
      721 ctaggggtgg ccggtcagcg ggggaagacc tcgaacggca cggccggacg accgccgaac
      781 cgcgccgccg cctgctgggc gttcccggtg aggaaggtac ggacgtactc ctcggggtcc
      841 tggtccgtga gcacctcgat gtacgccttg tgctccagca gggacttcac cgagcgctca
      901 agccccgggc cggcgtcggc cgcgtgcgtg ggcgtgctgg atccggccac cgcgacccag
      961 cgcacgccgt tccacggctg cagcccctgc tcgatgagct cggggaagat ccagcggttg
     1021 ccggcgtcac cggccgcgtc cagcacggcc cggccgacgg ccttgtggtc gggggtgttc
     1081 cagtagccac cgccctgcgc accgccccac gtgtcgcggt ggttgagggt gacgatcagc
     1141 tcggggcggt gccgccggat ggccgcggcg atgtcccggc gcaggccgag tccgtattcg
     1201 atggcgccgt cgtggtagtc caggaactcc acctcggaca cgccgacgac agcggcgctc
     1261 gcccgctgct ccgcttcgcg cagcggaccg cattcgtcgg gggcgatgct gtcgatgccg
     1321 gcctcgccgc gcgtggcgag gaggtagacg accttccggc ccccgtccgt ccagtccgcg
     1381 atcgccgcgg cgcacccgta ctccaggtcg tcggggtgcg cgaccaccgc gagggcgcgc
     1441 gtccagtcgg tgggcatggg ctgcaaggcg ggctgctgat caggttgttc ggtcatgtct
     1501 cgcacaatag gcgaatggac cgtcatgggc aggtggtggc gctgctcgac gccacgggga
     1561 tcttcttcga gccggcccgt accgcctttc cgggggcgga ggaggtcgcg tgggcccggg
     1621 ccgcggagct ggatccgggg gcgttcgggc ccgacggggc gtgggcactg gatttccggt
     1681 acttcgcgat ctcccggccc ggcgggcgct gggtgctggt ggacgccggg gtcggcccgg
     1741 cccggtcccc ggccgccgcg tgggccccgg tgccggggcg gctgccggac gcactcgcgg
     1801 ccgccggtat cgctcgggcc gatgtggagg ccgtcgtgct gacccacctt cacgaggacc
     1861 acgcggggtg gtcgtcgggg gacgacgggc ggcccttctt cccggcggcc cggtacgtcg
     1921 tgcagcgcgc ggaggtggcc gcgctgcacc gggcggaccc ggtgtgggac tggacggtgg
     1981 ctccgctgcg tgcgagcggg cagttgcacg aggtcgacgg cgcccaccgg ttggcgcccg
     2041 gcatcaccct gttgccgacg ccagggcaca ccccggggca ccagtcggtg ctggtggatc
     2101 agggggaggg agcgcgggac gtggtcgtca ccggggacgt gctggtgcac gcggttcagc
     2161 tgggcgaccc ggcggtgccg tactcccacg agcgcgaccg ggacaccgcc cgcgcctccc
     2221 gccgggccct gctggcgcgg gcgagggagc gcggcgcact tctcgccacc gcacacctga
     2281 cccgcgcctt cgtcgagccg cccccggaga cgacagcggg ccggcgcccc tgagcggaga
     2341 cgacagcggg ccggcgtctc tgagcgggga cgccggcccg gccggttgac gtgggatcag
     2401 ccgatcggcc gcggggtcgc gtcgatcccg gtggccgtcg cccggaacca gacggccttg
     2461 ccgtcggcgc cgacggcgga caggtcgacc agaccgtcgc ggtcgaagtc gcccgcggag
     2521 accagcgtcg ggtaggccgc ccggccgaag cccgagccga tcttcacgcg cagcgccgtt
     2581 ccccagctcc tggggtcgag ctgcccggcg gcgtccttgg cgcccttcac ggcgaagagg
     2641 tcgccggagg cgtcgtcgcg cacccacagg tcggcggcgc cgtcaccgtc ggtgtcgccc
     2701 gggaccagga ccgcgaccgt gtcccagccg ccgtcgccga cgaggaccgg ggcgccgttc
     2761 atgtcgaggt agccggagcg gctgcccgtg tacgcccaga gcttcgcacc ctgcttgacc
     2821 agcaggtcgg gctcgccgtc accgttcaag tcacccgcgt cggcgatgtc ctgggcgtcc
     2881 gaccagtgat cgttcccctg cgccgggtcg tcctcgatga cgctcaggac gatgccgtcg
     2941 tgcggacgga cgctgccgag gccgttgttg gggaagagcc ggagctgctt ggcccccagc
     3001 ccttcgaccg actcgagcac cagcaggtcg ttgtatccgt cctcgcccca gtccccgccg
     3061 gcggcgatgc ggctgccggg ggcgaaggac gcgccgccgt cgaccggtgc ggcgaaggtg
     3121 ccgtcggccc ggccggccga gaagcggagc ctgccgtcgg ggtccagggt ccacaggtcg
     3181 cgcagaccgt cgccgttcag gtcgccggcg gcgtcgcgga ctcctccgtt cccgagggcc
     3241 cagaagtggt agacggcctg gtccgagcgc cgcccggcct tgtcgacgct gtacgcgtag
     3301 agcatgtggg gaccggagcc ggtgggcgtg atcacggcgc tggcgcccgg cgccacagtg
     3361 acctcgcgcg gctcgaactc cgaccagtac acgatcttct cgatgttggt ggcgccaccg
     3421 gtgccgaacg tgaacgtgcc cggggtgcgg gccttgccgg tgttggcggg ggcgccgttc
     3481 gaggcgtcgg ggaactcggg tgagctgatc accggcggcg cggggcggcc gatggtggtc
     3541 tccagcttcg cggtcgccgg ggcgaagcgc ttccaggccg aggcgtcgga ctcgttcgcg
     3601 gcgaacagac cgacggtgac ggaggtccgg gacttggccg cggcctccgt caccaacgcg
     3661 gtggcgtcga attcgaggtc gccggccgcg cagccctcac ggcccttggc gtccgtcacc
     3721 gtcgccagcc ggacggcctt ggcgggctgg ttgttccacg tggtcttcgc cgagacggcg
     3781 ccgacgctcc acagctccac cggacggccc gtgcaggacg cggcccccgt gttggtgatc
     3841 cggaaggtcg ccttggatac cgtggcgccc gccagcgcgg tggtgtccag ccggaggtac
     3901 gcgcgggaca gcccctcggt gccggcctcg ttgccgacgc gcaggtcgcc ggcggcgttc
     3961 cagtaggagt ggttcgggta cttcttggac acgcgcgtcc aggcctgtgc gccgacgggg
     4021 gtctcccccg cccccccggc gctgacggcc ggcgcggcga cggcggccgt cgccggtccc
     4081 gccgccaccc cggccacggc cagtccgccg gccagggcca gcgagacggc actcgacatc
     4141 cttctcagca tgcacgctcc acacatcggt cggttcctcg ggtgagagca cccaccctaa
     4201 ccgtgtgatc aacttctgcg ggaacgatta atcgggggcc ccatcacacc cctgacctgc
     4261 gcggaccgcg actcacgcct cgtcgcgggc gagggacagc aggcggtcca ggacacgggg
     4321 gccgccggca cggacgccgt cgtgctcgaa ctcgtccgtc acccaggtcc gcaagccccg
     4381 gatggagcgg gccgtctcca acgagtgcgc ggtgtccacg tacatgtcgt cgtggtagac
     4441 ggcggcggcc accggcacct cattggcggc caggcgggcc ggatcgtaga ggggctgcca
     4501 gccggtgcgg gcggccagga gttcggcggt ctcgcgcagc ggggcgaggg ccgggtcggt
     4561 ggtgaagtgc caggggtgga tggtctcgcc ggtgaagagc agcggctcgt cgcccgcgag
     4621 ggccttgtcc gcgtcgaagc gggggtggcc ggcgcgcacg cgttcggcgg cccaggcggt
     4681 gggggtggcg gggtcctggg cgtagatcgc ctcatggtgc agcgcgtaga gggggtgtcc
     4741 ggcgaaggag agcaggccgc gggcgctctc caggaaggcg tcggagaggg cgggtcccgc
     4801 gggggtcggg acgaaggcgt cctccagcag gtagtggagc tggtggctgc cgtcgccccc
     4861 gccgaggagg atgccgaggg actggaagcc ctcgacggtg aggcggtggc cgccggggag
     4921 ttcggccggt gcttgcgcga ggtgggcggc gatccggcgg gcgcgttcga cgtccatcgg
     4981 gtagcgggcg tagtgggcca ggttcttgcg ctcgatgcgg gggtacgcgg cctcgtacac
     5041 ctcgtcggcg gtggcggtca gggacggcag gccaccggtg atcagcgcgg ccgtgaggcc
     5101 ttcgggcgcg gtggagaggt agcgggtcgc acagaagccg ccgaagctct ggccgagcac
     5161 ggtccagggc gcgccgccgg tcaggccggg ccggatggtt tcggcgtcgc gcacgatgga
     5221 gtcggcgcgg aagtggctga ggtactcggc ctgccggtcg ggggtgccgc gcaggggcag
     5281 ggtctgccgg ttcaccgggg tggagcggcc cgttccgcgc tggtcgagga ggagtacccg
     5341 gtactcggtc agggcgcgct ccagccaggc ctggcggccg atgaaacggc gggcgccgaa
     5401 gcccggaccg ccctccaggt agagcagcca cggcagcgtc tcggggtcct tgccggcggc
     5461 gacgacctcg cgggcgtaca gctcgatccg ctccccgtcc gggcgcgcgt ggtccagggg
     5521 gacggagaac cggtggtcgg tgaggaccgt gccgggctgg cggtagctgt gtgcggtggt
     5581 cacggacggc ccccaggggt acgaggtgat gaagaccgcg ccccggccgg gtggcggcgg
     5641 gggcgcgggg tggtggcccg attctaggcg ggccgggttc ggccggacgg gccggcggtg
     5701 tgccggaccg gtgttgccgg acggggcgtc agaactcgac gaccgagcgg aggacctcgc
     5761 cgcgttccat ccgggcgaag gcgtcctcga ctccgtcgag cgggatggtc tcggagacga
     5821 aggcgtccag gtcgagccgg ccctgcaggt agaggtcgat cagcaggggg aagtcgcgct
     5881 cgggcaggca gtccccgtac caggaggact tcagggcgcc gccgcggccg aagacgtcga
     5941 ggagcgggag ttcgagcttc atctccgggg tcggcacgcc gaccaggacc accgtcccgg
     6001 cgaggtcgcg cgcgtagaag gcctggcggt aggtctcggg gcggcccacg gcgtcgatga
     6061 ccacgtccgc gccgttgccg ccggtcaggc cctggatggc cttgacgacg tcgtcggtcc
     6121 gcccgttgac ggtgtgcgtg gcgcccaggc cccgggccca ttccagcttc cggtcgtcga
     6181 ggtccacggc gatgatccgc gaggcgcccg ccaggcgggc tccggccacg gccgcgttgc
     6241 ccactccccc gcagccgatg acggcgacgg agtcgccccg cccgacgttg ccggtgttga
     6301 gggcggcgcc gaggccggcc atcaccccgc agccgaggag gccggcggcg gccggggcgg
     6361 cggccgggtc caccttggtg cactggccgg cggcgaccag ggtcttctcg gcgaaggcgc
     6421 cgatccccag ggccggggag agcggggtgc cgtcctccag ggtcatgggc tgggtggcgt
     6481 tgtgcgtggc gaagcagtac caggggcgtc cgcgcctgca ggcgcgacag gtgccgcaca
     6541 ccgcacgcca gttgaggatc acgaagtctc cgggcgccac ggaggtgacg tccgggccga
     6601 cggattcgac gatgccggcg gcctcgtggc cgagcaggaa ggggaactcg tcgttgatgc
     6661 cgccctcccg gtagtgcagg tcggtgtggc agaccccgca ggcctgcacc cggacgaggg
     6721 cctcgccggg tcccgggtcg ggcacgagga tcgtcgtcgt ctccaccggt gcgcccttgc
     6781 tccgggcgat gacccctcgt acgcgatgcg tcacgtcgta ccccgctctg atcgaatcgg
     6841 tctggatcaa cgaacgtaca cgggcggcac ccggtacggg agttgtgtca cgtcacggcg
     6901 cgcgacccgg ccagatccgg tggtacggcg gcccgaagtg ccgcgccgaa ggccgccacg
     6961 gcggggtggg cgccggcgcc gctgcgaaag gcgaggttgg tacggcgctg catgagcagg
     7021 cgcgtgaggt gtacggcagg ccggtccggg ccggtgaccc cgagctgggg cacgacggcc
     7081 acgccctggc ccgccgcgac gagggccagc acggtggcga actcgtcgac ccggtggcgg
     7141 acgcgcgggg tgaagcctgc ggcctggcag gcccggaccg tcatggcgtg gcagagggtg
     7201 ccgggggtgg cggtgatcca gggcgcccgg gcgtgggtac gcagggccgc tccctggtcc
     7261 ggttccggta cccctggccg gccggaggcc gggtcggcgg gcgcggccag gtacatcgcc
     7321 tcgctgtaca gcggttcggt ggccagcccc ggctcgggct cggccggtac gaagtcgtac
     7381 tcgtgcacca gcgccacgtc caggtccccg gctcgcaggg cgtgtgccac cgcggccggg
     7441 tcggtctccg agaccatcgg ctccagcccc gggtggcgcc gggcgagggc gatcagcgcg
     7501 gccgggacga tggcccgggt cgctgtgggg aaggtgccga tccgcagggc accggcgagc
     7561 ccgccgcgcg cctcggcgag atcggcctcg gcctgttcca gctgttcgag gacggcctcg
     7621 gcgtgccgga ccaggttctg gcccgccggg gtgagccgga cccggcggcc ggtgcgctcc
     7681 agcaggggca ggccggcttc gcgttcgagg acggtgagct gttgggagac cgccgaaggg
     7741 ctgaaggcga gggcgtcggc gacggcgacg atggtgccgc ggcgggccag ttcgcgcagc
     7801 aggcgcaggc gtcgtacgtc gagcatcggc tcagcttacg gttcgggtaa gaaacgcgaa
     7861 ctggatttga tcctttccgc gggccagtct cgtcgacatg gcacaggaca ccgcagacac
     7921 cgcagacacc gcagacaccg caacgacagc aacgacagca acagcccttc cggcccgacc
     7981 cctgcagggg atccacgtac cgctcgtcac gcccttcacc cgcgccgggg aggttgcagc
     8041 cgaggcgctg gaggcgctcg cccacgaggt gctcgacgcg ggcgccaccg ggatcgtcgc
     8101 gctgggcacc accgcggagg cggcatgcct cgacgaggcg gagcgcgacc tcgtcaccgc
     8161 cgtgtgcgcc cgggtctgcg gagagcgggg cgcgccgctg atcgtcgggg cgggggcgag
     8221 cggcacccgg gccgccgagg cctcgctggc cctgctggcc cggtggcccg cggtgcgggc
     8281 ggcgctggtg acggtgccgg cgttcgtccg acccgcggcc gccggtgtac tggcgcactt
     8341 cgcgcggctg gccggtgcga gcccggtccc gctgatcgtc tatcacgtcc cgtaccgcac
     8401 cgggcagccg ctggacgcgg ccgcgctgcg ggcgctcgga tcgctgccgg gggtcgtcgg
     8461 ggtgaagtac gcgggcggcg gcatcggcga ggacgcggtg gcgctgctcg gtgacctgcc
     8521 ggccggattc gaggtgctgg cgggtgacga cgtgtacctg tcgccgctgc tggcgctggg
     8581 tgcggcgggc gggatcctgg cctcggcaca tctggcgacg ggccgtttcg cggagctcgc
     8641 cggggcatgg cgggcgggtg acgtggcgaa ggcccggccg ctggggcacg cgctggcccg
     8701 catgtcggcg gcggccttcg ccgagccgaa tccggcggtg ctcaagggcg tcctgcacgc
     8761 gcaggggcgg atcccgaccc cggacgtccg gctgcccctg ctaccggcct cggagggagc
     8821 cgtgaaggcg gtgacggcag cgctggaggg gctggagggg ccggtgtgac ccgaggggtg
     8881 aaccggccgc cgagcggagg tgagcgggcg gcggagcatc agccccggac ggccggcaat
     8941 ccgccggaaa gaatccctaa tgggcgattc gccgcctacg ggccggtcgc ccgaatgcgg
     9001 cacccggaga gcggacttgc ccgaattggg cgcccggtcg tcgacccgtg atatgagcca
     9061 caccgaacac ctcaacatca tttcccgcaa atagccggtc cccttttccg gaaagggaat
     9121 cggctattgc gccatgccgc cttcaaggtc atttacccga ccgaaagcga gatgtcgatc
     9181 tatcggtgga attcggggct tgttcgggca cggcgcgctc gcctacggtc acctcgttcc
     9241 tggtggtcag gtgccgaatc cggcccccgc ccgggatctc ccgtcccccc acgtgaggaa
     9301 ttccgccatg cctgcaaagg gtaagcaccg tcggccgaag cactaccgga tcacccgcaa
     9361 gctggctctc gccggcaccg gtggcgcggc cctcactctc ccgctgatca gcgcgaccac
     9421 cgccggagcg gtggagaccg ccgctcccat gacctattcc gtggtcgcgg gcgacaccct
     9481 ttcggagatc gcggcgcagc attccctcag tggcggctgg cagcagctct acgacgcgaa
     9541 caagaccgtc gtcggtgaca acccgtcggt catccgcccc ggcatcaaac tgaccatcgg
     9601 caagcaggcg aaggcggccg cggcggccaa gaccgccgcc gtcaagcccg ccacggccta
     9661 cccgaacaat ctcgacgggt ggatccgaga gtccctcgac gtcatggcga agcacggtat
     9721 tcccggctcc tacaacggaa ttcaccgcaa cgtgatgcgc gagtcctccg gcaacccgct
     9781 ggcgatcaac aactgggaca tcaacgcccg gaacggaatc ccgtccaagg gcctgctcca
     9841 ggtcatcgac cccaccttcc gcgcctacca cgtacccggc accgcgcagg actcctacga
     9901 cccggtcgcc aacatcaccg ccgcctgcaa ttacgcagcc gcgcgctacg gctcgatcga
     9961 caacgtcaac gggccctact aggaaactcc ctgcaccggt tcacaccggg cgacgccggg
    10021 cggcgcggac gaggatccgc aggggcgccg ccaggccgta cccggtgtcc cggcgcaggg
    10081 cggcgacccc cgcgcgctcc acggcggtca gctggtgcgc catcagctcc gtcatggtcg
    10141 cgatcacggg acgcagcccg ggctcggcga ggtcgaggat gccgcgggcg gcgtccagag
    10201 ccgtacgggc acgccggcac tcggcggcga ggagggctcg tacggccggg gtgtcgcggg
    10261 cctgttccag gtcggcgcgg gtcaccgcgt ggtcggcgag acgggcgcgg gggatgcaga
    10321 gccggccgtc cgcgaggtca ccgcagaggt ctgcgaggaa gtccacgcgc tgggcggcgt
    10381 cgacgaagcg ccgccagccc gccgcttgtt cggggtcggg gccgccccgg tactggagcc
    10441 cggtgaagac cagcaccccc ggccacgcgt acgcgtcgag gtaggcctgg aagtcctcct
    10501 ccgcctcgaa gccgtcgaat ccggcctcgg cggtggcggc acccgccagg aagcgggaga
    10561 cccagtgcgg cggcaggccg cgggattcca ccgcgtgcgc gtaggcccgc agcagcgggt
    10621 cgggactgtc cccggacttc agggccgcct ccacccgctc ggacaacgcg gcgagaccgg
    10681 cggcccgttg cgccgcggta ccggtctcgg cgacgtcgtc gaccaggttc atgaaggcga
    10741 gaccggcggc gaggcagggc accagcggcg gcgaggcgag catccgcagc gccaggtacg
    10801 gggccggctc gcggcggagc acccggcggg cggcgtacgt gtagtcgtcc cgcaggcggg
    10861 atccggacac accggccgcc gtgagggtgg tgcgccagct gggcatggtg gtcgtgctcc
    10921 ctgacctgtc ggaccgtacg tgcgtacggg tacaggatgt caggagccga cgaccttctt
    10981 gaccttgccg tcgatgccgg ccagcacata gccgccgcgg ccgtactcgt cgctgaggta
    11041 ggggcgcatg cacgggacct ggtccatcat ccacggctcg acgatcacat aggtcgaggt
    11101 cggcttctcg acccccagct ccttcttgga ctgctccagc aggccgggca gcgcgtccca
    11161 gttgacggtc gacatgtcga tcagcggctc accctcctcg accgtgccgt cggggccggt
    11221 gcgcttggcc gccccgtccc ggtactgcca cgcgtcgacg gtctcggcgc cgggggcggt
    11281 ggggatcgag gcgagcacgt acccgtcgta gaccttgagg tccacgaagg tcgtggtccc
    11341 ggtcttctcc ttgagcgccg cgagggcggt ccggatgttc tgcggggtga gcatgctgcc
    11401 gcgggccgtg ccggcctggg acgtgctcgc cttcggtcgg ggggtcagga cgggggaacc
    11461 ccccggggtg gcggcgacgg gccgggtggc gcgggcgtcg acggcgtcgt cgtcgccgga
    11521 gttcccgtcg ggcagcgact ggacgatccc gacgacggcg gccgcgagca ccaccgtgag
    11581 cgcggcgccg atcagggccg ggcgccggcg cggggcggac gccagcggaa cgggcgtggt
    11641 cgtggacccg tacggggagg aaccggcgcc gaacggaggc ggggtgggtg atccgtaggg
    11701 gccgccgtac gggccgaact gccccgggac ggccggcgcg ccgccgaccg gcgtgacggc
    11761 ggcgagcggt gccgggacga tcggcggtgc cgggacgacc ggtgctgcgc ccgcgccgta
    11821 gccggacccg agagcggcgc tcgcgtcccg gagcagctgt tccagctgcg ccccgtcggg
    11881 ccgcgccgcc gggtcccgta cgagcagccg ttccagtacg ggcgccagcg ggccggagcg
    11941 cacgggcgcc gggatcggct cgtcgagcac ggcgacgacg gtggccaggc tggtggcccg
    12001 gcgcagcggg tgaaccccct cggcggccac gtagagcagc atgcccagcg accacaggtc
    12061 ggaggcggcc agtccctcct ccccgcggac gcgttcgggc gcgatgtatt cgggcgagcc
    12121 gatcagcacc ccggtcgagg tgagcccggt ggatccgtgc agggccgcga tgccgaagtc
    12181 ggtgagcacc gccgacccgc tggggcgcag cagcacgttg gccggcttca catcgcggtg
    12241 gagcacccct tcggcgtgcg cggcgcgcag cgcggagagc acgtcgaggc cgagccgcag
    12301 cacgtccgcg ggcggcatcg gaccggatgc cagccggtcg tgcagcgagc cgccctggac
    12361 cagctccatg acgatccacg ggtgcccgtc cccgccgtcg ggcggttcga cgatgtggtg
    12421 gatcgtcacc acgtgcgggt gggcgaggcg ggcgagggcg cgggcctcac ggacggcccg
    12481 ttcgcgcagc tggtcggcga gaccgggctg ggcggcggcg gtcgccgggt ccggcgggcg
    12541 cacctccttg agtgcgacct cgcggtgcag ggcgatgtcg cgggcgcgcc acaccgtacc
    12601 catgcccccg ctgcccaggg gtgcgaccag ctcgaaacgg ccgtcgatca gctgtctgcc
    12661 ggcctcactc gtatccatgg ccgctcatcg tagggggcgg cggactcagc agcgtcggcg
    12721 gtccaccgtc agggtgccct ggacggtggc caccgtacgg tcgtaacacc cgcccagcac
    12781 tgtggacccg tacaaccggt agcgggcgga ggtggtggcg accgcgtgcc gctggtcgcg
    12841 cgggacgttg gcggtgtagg tggcgtcgcc ggtgtaccgg tcgtcgagcc ggacgctgtc
    12901 gacggtgcgc ccgccgcgca cggtgacggt gtccgcccgg tccccgagcg cgaggacggt
    12961 ccgcagccgg tcgccctccc cgagggtcgt ctcgccgtcc atcgtgtagg tgcggtcggt
    13021 ccgggtggtg gtcggcccgt gcgtcacact ctcctcgtcg gtccaggtgg cggtgagccc
    13081 gtcctggttc tcgccgtcgg tccagcggtg gacggaggtg ctccgcacgc tgcgggtgac
    13141 ggtggtggcc acccggccgc gggaggtgtt caggtgtccg gcgacggtca gccggtgccc
    13201 gccctcggtg tccaggcggt gctgtgcgcc ggggggcgcg ggcgtccagc gggagtggcc
    13261 gctcggatcg ctctcctcgt gccgggtcag ggcgccggtg acgacctccc gggcctcgtc
    13321 ctgccagagc agcagattgg tgggggtgct ccagccgctc tgtccggctg gcaccccggc
    13381 gaccgatacc tcgatccggt gcgggcggcc gtcgttgagg agggcggcgt agggggtgag
    13441 gtcgtagcgg atcggctgga cgtcgaaggc gcgcgggccc ggggtgacgt accagaggaa
    13501 ggggttggac cagccgccgg tccagaccgt ggggaagggc gcggcgatgc cggcgagttg
    13561 tccgtcgacc gagacgcgga cctcgcggtg cgggccgtcg gtggccttgc aggagtacgg
    13621 ggccgcgtcg ggcgtggtca tgtaccagta ctcctcgcag ccgccgcccg agccggtggc
    13681 gtagacctcg gcgaggaggc gctccgtgtt gcgcggggtg gtgacggccg gggaggtgag
    13741 gggcaggacg cggtcggggg tgtcgggggc ccgggtgccg ccgtcggcgg cgtagaaggt
    13801 cagggtcacc ttgacgtcga tgacgccggt gtaggtgtcg tcgacgacgt tgccgatgag
    13861 catctcgacg ggctgcgggc gggcgagggt gtcgcggtat cgggtgacgt ccttctcgac
    13921 ggaccaggtg atgccgtcgg gcgagggctg cggggtggag gtgcgcagga tctccacccc
    13981 gccgagggag aggtggccga ggcggtcgta ctggcggccc ttgaccttgc cctcgaggcg
    14041 gaggaccacc ttggcccagg cgtcggcgcc gcagccggtg ggcggtgcgt agttgccccg
    14101 gtagggggtg aagtcactga accgggcttc cgcgagggtc acttggcagg accgggtcgc
    14161 gggccgggtg acgggcgggg tcgcggtgag gggatcgtgc cagtcggtcc cgaactccgc
    14221 gggcggtggg tcggcgggct gggtcccggc gggcgcgggc gccgcggcgg ccagggtggc
    14281 ggcggtcagc gcgatggcgc cgagcagacc ggtgatccgg tgtcgtcgtc tcatggaccc
    14341 gcagtgaaac ccggcccgcg acggccgtgc cagggccggg acttcggccc tggccggttc
    14401 tggtccgccc gggccggccg gcagcggggc aagtcaaccg ggtgcgtcag cggggcagga
    14461 cgaccacgcc gtcgtcgtcc gcgtggacgg tgtcgcccgt gcggaaggtg atgtcgccga
    14521 tggtgacggg ctcgtcgacc gcgccctcgc cggtcttgcc gctcttgcgg gggaccgtgc
    14581 cgagcgcctt gatgccgagg tcgaggccgc cgagggcgac gctgtcgcgg accgaaccgt
    14641 tgatgatcag tccggcccag ccgtgggcct cggccgcacc cgcgatgagg tcgccgacga
    14701 gggcggtgcg cggcgagccg ccgccgtcca cgacgaggac cgcaccctcg cccggcgtgt
    14761 gcacgagggg gcgcagcagc gcattgtcct cgaggcagcg gacggtccgt acggggcccg
    14821 cgaagagccg acggccgccg aaccggcgga acccggtggt gcagatggcg agggactcgc
    14881 cgtactcgtc gtacaggtcg gctgtgggga cgggggtgac gctcatcggg taccggtttc
    14941 ctcgctgctc gtactcgaac tggggctcgt ccatcgcggt ggtgcggccg gcgtaatcgg
    15001 cgggtcgttc ggagcccccg gacggccgac cgggagcgcg accggacccg cgcgcaggta
    15061 gcgaccaggg cggccggcag cgggaggcgg cggtcggtgg acatcggccg gaacccgtcc
    15121 cggtggtcgg cccgggcgcg ccgtcgggca cgatcgggac actacggccg ggcgggagac
    15181 gtacaaggta ccggcggcgg gacgggccgg ccgggcggga cgggcgccga cccgccgggg
    15241 agcgggtcag tcgcgggagt tgccgaacag gatgcggtag ccgatcagca ggaccagcga
    15301 gcccgcgatg gcggagcccc aggtggcgag gtcgaagaac tcggtctgga tcggcttgtc
    15361 caggaccttc gccgagagcc agccaccgat gaaggctccg gcgacaccga tgagggtggt
    15421 gccgatcagg ccaccggggt cccggccggg cagcaggacc ttggcgatgc ctccggccag
    15481 cagccccagg atgatccagc tgacgatccc catgtccagt cactccgctt cggtcggccg
    15541 gtcttccggt cgttcagtcg ttcggacgtt ctcctcggag gacgcgaccg gggccgaatc
    15601 ggttctccgc ggctcagacc gccacgcggc cgaccggtac ggggagctcg gcacccgcga
    15661 cggaacccgc ggcggtgccg acgcccggac ccgccgcggc ggagggcgtc cgggtgagca
    15721 gcatgactcc gcgcgcggcg agcagggctc cggtggccgc cagcagcagc cctgccggtc
    15781 cgccctggag ccgttcgccg agcaggacca tgccgatggc ggcggcggcc agcgggttgg
    15841 ccaggttcac cacggcgagc ggggcgccga gtccgccgcg gtaggcccgc tgcgacagca
    15901 gcatcccgcc gaccgcgaac accatgacga gcagggccac ggagacgacg cggacgctga
    15961 gcagggctcc gccgcgcccg gccgccacgg ccacggtctg ggtcagggcg gaggcggccg
    16021 cggaggccag gccggacgcg gtggcgtggc gcagccccga gcgagggtcc ttgaccgcgg
    16081 tcagcatcat gatcacggcg atggtcgcgc cggagacggc cagcgcctcg accagcgtga
    16141 gggtgtcgtc gggggccggc ccggaggccg ggagcagcag caggccgagc ccggcgacgg
    16201 tggccagggt gccccgccat tcggtggccg ccacccggcg gccggacctg cgcgcgccca
    16261 gggggacggc ggccaccagg gtgagcgcgc cgagcggctg caccagggtg agcgggccgt
    16321 accgcagggc cgccgcgtgg agcagcgcgg cggcggcgtt caggccggcc gaccaccacc
    16381 aggcgccgga gcccagcagg gccccggcgg tgcgtgcgac ggcggcccgg gcgaggcgct
    16441 cctgggcgac ggcggcggcc gcgtaggcca cggccgaggc gacgcagagc cccacggcga
    16501 gggtggtgtc gttcattgtc ctgctcctac ggccgcgtcc gcgctccgcg ggcgcggcag
    16561 gccccgtacg ggcccgtcgg ggtcgttctc ccgagccgcc tcggggtcgg gccctgcctc
    16621 gtcgtccggg gcgtcgtcgc gcggcctcgg gaccagcagc agagccgctc cgaggaggac
    16681 ggcggcgacg acggcgtcaa gccagtagtg gttggcggtg ccgactatca cggtcagggt
    16741 cagcagcggg tgcagcagcc acaggaggcg ccaccgcgag gaggtggcgg cgatcatgcc
    16801 gagggcgagc atcagcgccc agccgaagtg cagtgagggc atcgcggcga actggttggc
    16861 cagggtgtcc tcggccggtg ccgcccggta gacgctgggc ccgtagacct gcgccgtgtc
    16921 gatgagctgc gtggcgtcga gcaggcgcgg gggcgcgagc gggaaggcca ggtgcaggac
    16981 gagggcggct gcggtgagtg cggcgaggac ccggcgcgtc cacaggtagt gggcggggcg
    17041 ccggacgtag agccagatca ggaagagcgc tgtcgcgggg aagtggactc ccgcgtagta
    17101 ggtgttggcg gtggtgacga gggcgtcccc gtgcagcagc agctgctgca ggaggccttc
    17161 gccgggcagg tgcagggcgc gctccgcgtc ccatattcgc tccgcgttgc ggaaggcctc
    17221 ttcggtgcgg tcggtcgaga gcagccggcc cgccttgtag acggcgaaga agcccgcgac
    17281 gagcagcagc tcgcgtatga ggcggcggcg cgcggctctc ggtccggctg ccgactcggc
    17341 aggtgtggtg tgggagctca tcccccggtc tctcttcctg tttacgcgca cagcgacacg
    17401 ccagtgtatc gatacattgg cgtatcgata cgctggtgta ccgatacggt tgcgttcccg
    17461 tacacttccg tagtggaacc tgccgccgag gcgcccccga ggagagccgc atccatgacg
    17521 tcgacaccga cccccgcacg ccgctccaag atcaccccgg agcgtgagca ggagttctac
    17581 gacgccgtac tggagcagct gcgcgagcac ggctacgagg ccctgaccat ggagggcgtc
    17641 gccgcccggg ccagctgcag caagtccacg ctctaccggc agtggaagac caagccccag
    17701 ctcgtcgccg ccgccctgcg tgcggggcgg cggggcactc tcgtcgccgt ggacaccggc
    17761 tcactggcgg gcgatctgcg cgaggcggcc cggatcgcgg ccggcacctc gggcagggac
    17821 acccggctga cgcaggccct cgggcatgcc gtgctcagtg acgaggagct ccaggccgcc
    17881 ctgcgcgagg cgctggtcga gccggagctg gccgcgttcg ccgagatggt cgggcgggcc
    17941 gtggcgcgcg gcgagatcgc agcggaccat ccggcggtgg agttcctgcc cgcccagctg
    18001 atgggcgtgc tccggatccg gccggtgctg gaagggcggt acgccgacgc cgactacctg
    18061 gtccggttcg tcgacgccgt catactcccg tcactgggcc tcgcaccctc ccaccccgcc
    18121 cggcccccgg ccggtcaggc cccctgaacc ggcgggccgc cgtcctgatg acctgacggc
    18181 gacctgcccg cgctgcctcg tggggacggc ggcagcgcgc cgcccggacc gggcggcgac
    18241 cactcacccc aggagtggtc gccgcccgat ctgtgcggct cccccgtccg tgcagcgctc
    18301 cgccccctgg gccccgatcc gctcgactcc ccgtcggccc gggcggtcgg cctcagccga
    18361 gtgcgcccat ggtccgggcg aattcgtccg ggtccgcatc ggagccccgc agccgaaggt
    18421 cgaaggacca ggcgccggac gcatcacggg tgaactcggc gaccgtggca gcggtcgcgg
    18481 cggccacggc cgcgaagtcc ccctcggcaa ggtccgtgtg gccctcgcgg atccggaacc
    18541 cggtgccggc gatgtccgcg aaggtcttcg tacgaccctc ggggcccgcg tcggagttct
    18601 ggatgaccac gccgaccacc acccggctcg attcctgcgc catccggtgc agctcgatgg
    18661 tcatcacctc gtcgaagccg aagccctgcc cggtgtggct gtcccggttc agtgcgatgg
    18721 tgccgtcggg cgaccgactg ccgaagtgca cggactggac gggcgtcccg tggaggtccg
    18781 cagcgccgta gaccgcggcg actatgtcga ggtcgttcgc gggcgcgccg gccgggctgg
    18841 gatcccatcg cagcgcgaac tccaccttgg ccaggccctt gcgtacaccg gtcatcgaac
    18901 tcccccttca ctcacgggca ttgcccgtcc atgatcccac gagccccccg gcccgctccg
    18961 gaagaccgcc cgttcccggc cagtccgacc gaactggccg gttcgacgaa accgactcat
    19021 tcgacccaat tgaccactct gggagaaaac acccaaaccg ggtgtaaata gaggagtacc
    19081 gaattcgggc aggcgcgtgg tgccgacaaa aggtgaggct gcctattttt cccgctccgc
    19141 cccaggtcag ccgcagaatg cgccgcagaa ccggattgtt atcctcaagt tttcctcaaa
    19201 tgtagtgacg ctgcgcccgt ccgcttccta gcttcctcgt acacgcgtcc ccgcgttacc
    19261 cgtattcgcg cggttccaca cgcccccggc gatcccggtg acgcgccccg cgtccctcag
    19321 gaaagagtgc agcatgaagg ttccccaggc cggcgcggtc gccgcagtga tcgcaatcgc
    19381 cctgaccgcc tccgggtgcg tcggtgacga aggggaccag ggggacggga ccctcgccat
    19441 cggcatcaag ttcgaccagc ccggcatcgg aatgcgggaa accgacggca ctttcaccgg
    19501 cttcgacgtg gatgtcgcca cctacgtggc caaggagctc ggctacaagg ccaacaagat
    19561 cgaattcaag caggtctaca gcaacgaccg cgaactgctg ctccagtaca acgaggtcaa
    19621 gttcgtcgtc gcgagctact cgataaacga gaagcgcaag gagaaggtcg atttcgccgg
    19681 cccctacttc gtcgcgcacc aggacctgct gacccgcgcc ggcgacgcgt cgatcaacaa
    19741 gcccgaggac ctcaactcca agagcctgtg ctcggtcacc ggttccacct cggccgagaa
    19801 cctccgcaag aacctcgccc ccaaggccgg cctgctggag ctcggcggct attcggactg
    19861 cgtcgtcgcg cttcaggaca gccgggtcga cgccatgacc acggacaacg ccatcctggc
    19921 cggctacgcg gcgcgcaagg gcaacgaggg caagttcaag ctgctcggcc agaacctgag
    19981 caacgagaac tacggcatcg gtgtcaagaa gggcaacaag gacctccagc gcaagatcaa
    20041 cgacgcgctg aagaagatgg tcgcggacgg ctcctgggag acggccgtga agaagaactt
    20101 cggttcgaac tacaagtacg agccggctcc ggcggtcgcc cccgtcggct gacggccacc
    20161 ggggcggtgg cggtctcgcg agcggcttga aacgggcctc caccccgcac gacccgacgg
    20221 ccgtgatccc ctgacgaagg gggtcacggc cgcccgtgcg atgccgctca gaccaccggg
    20281 gccttgctcc gcagcacggt caggaactcg cgcatccagc tcgagtggtc gggccaggcc
    20341 ctggccgaga ccagcgtgcc gtcgaccacg gtctcggcgt cctcgaactc ggcccctgcg
    20401 gcctccatgt ccagttcgag cgccgggtag gcggtcaccc ggcggccggt cagcccgccg
    20461 gccgcagcgg tgatcagcgg gccgtggcag atctgggcga tcggcttgtc ggcttccgcg
    20521 aaggcggcca ggatccggcg cacctcgggg tcgttgcgca gatactccgg cgcccggccg
    20581 cccgggacga ccagggccgc gtagtcctcg gtgaccacgt ccacgaaggc cagatcggcg
    20641 ggccaggtgt agccgggctt ctcggtgtag gtgtcgaacc cctcctcgaa gtcgtgcacc
    20701 acgaaccgca gtttcttcac ctgcggcgcc gcgatgtgga cctcgtaccc ctcctcgcgc
    20761 aggcgctggt acggatacag gacctccagg gattcggccg cgtcgccggt cacgatgagg
    20821 atcttcactg ccatgggctg ctccagatag ggctggtcat ggtcggtccg gcccccgccc
    20881 ggggccatcg ctaccctgcc cgcggc
//
