LOCUS       NZ_BMVL01000002        38404 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces avidinii strain JCM 4726 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVL01000002
VERSION     NZ_BMVL01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces avidinii
  ORGANISM  Streptomyces avidinii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 840996)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650695.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:24:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,659
            CDSs (total)                      :: 7,582
            Genes (coding)                    :: 7,337
            CDSs (with protein)               :: 7,337
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 80 of 245
            Pseudo Genes (incomplete)         :: 200 of 245
            Pseudo Genes (internal stop)      :: 10 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:19:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 38404
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVL01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..38404
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..38404
                     /SMILES="NC(CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)C)C(=O
                     )O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..38404
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[15218:18404](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(15219..18404)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..33295
                     /SMILES="NC(CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)C)C(=O
                     )O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..33295
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[11444:13295](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(11445..13295)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     gene            <1..502
                     /locus_tag="IE257_RS37810"
     CDS             <3..502
                     /codon_start=2
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE257_RS37810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229920105.1"
                     /transl_table=11
                     /translation="IEDEARGGTNAEIIDRAPTQEPAQFNRPLHIPLQHSQPTITAAAQ
                     TVDDQQFSPQPAHREINTDGMGQLLPPILLLDHAGEYETRRSCIEVVTSDAPQVSQVSQ
                     QHVEGETVIRRRGPELPQPVKVEHGMRDPAIGEEVAPRLGNGGFPHAYDAIDQESPSSP
                     GAA"
     misc_feature    276..278
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(765..1172)
                     /locus_tag="IE257_RS04110"
                     /old_locus_tag="GCM10010343_08320"
     CDS             complement(765..1172)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020557731.1"
                     /locus_tag="IE257_RS04110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08320"
                     /product="PPOX class F420-dependent oxidoreductase"
                     /protein_id="WP_189964822.1"
                     /transl_table=11
                     /translation="MSVVLSEELRKVIDDTPVFASVATIQPDGSPQVSVTWLARDGDDL
                     LVSTTVGRRKERNLRRDPRVTVLVNPSDAPYTYAEIRGTARLTTEGGQELIDALSRKYT
                     GKAYADFNPASAEDNERVVVRITPRKVVGSL"
     gene            complement(1428..1793)
                     /locus_tag="IE257_RS04115"
                     /old_locus_tag="GCM10010343_08330"
     CDS             complement(1428..1793)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510392.1"
                     /locus_tag="IE257_RS04115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08330"
                     /product="DUF1330 domain-containing protein"
                     /protein_id="WP_189966105.1"
                     /transl_table=11
                     /translation="MSAYGFAHLRSRRNHSDILEYLERIQATLDPFAGRFVIHGPPVEV
                     VEGEWPGSMVLIEFPGLAEARAWYDSPAYRAILRLRTDHVEGDVVLIEGVGPNCDPAER
                     ARKLRTEAGREGGRSTG"
     gene            2165..2746
                     /locus_tag="IE257_RS04120"
                     /old_locus_tag="GCM10010343_08340"
     CDS             2165..2746
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606535.1"
                     /locus_tag="IE257_RS04120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08340"
                     /product="hypothetical protein"
                     /protein_id="WP_189964824.1"
                     /transl_table=11
                     /translation="MIASMVPPAGAGWEEQHRFTTEVTALLAARYGRWVCGWHWAVGEG
                     GGGGVVTSWCCTSHSIGEPAETAARVIASLLEWRDWLEELAEKFARLAPPAGADAEGRS
                     WHLERAATRLVTVVVDRTGAECGWYGLCHTVLTWFLSSTGMGPERAKDAVETAIGGRFK
                     SWTEPPRRLVDAVGEDLAVGLTGELPYRDR"
     gene            2736..3371
                     /locus_tag="IE257_RS04125"
                     /old_locus_tag="GCM10010343_08350"
     CDS             2736..3371
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374533.1"
                     /locus_tag="IE257_RS04125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08350"
                     /product="Fic family protein"
                     /protein_id="WP_229920106.1"
                     /transl_table=11
                     /translation="MTADALAAWCHVRSQVDWASAAGETPAPVEAAMDGLVAWCDAGGR
                     ASDPARADRLLAAVAQSRADASHKRPLTCALLTEWQQLVLGLPGVEFRQGDAFAKGGRE
                     RYALTPHTRRDFERCLRDSADLRVPLASRAARAYLDVAFFHPFDDGNARLAMLTLAHVL
                     ELEGVRLDRTGPLQTTRYADDAAGAADLAVLVSVLIRSTHQRAARARP"
     gene            complement(3616..4467)
                     /locus_tag="IE257_RS04135"
                     /old_locus_tag="GCM10010343_08360"
     CDS             complement(3616..4467)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049258.1"
                     /locus_tag="IE257_RS04135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08360"
                     /product="aldo/keto reductase"
                     /protein_id="WP_189964826.1"
                     /transl_table=11
                     /translation="MQTVTLNNGIGMPILGFGVYQIPPEQTEQAVADALAAGYRLIDTA
                     AAYGNEEAVGRAIKNSGIPREELFVTTKLWIQDAPAEENTRRALETSLTKLGLGHVDLY
                     LMHQPYGDVYGQWRAMEAAGREGLAKAIGVANFYPDRLLDLILNNEIAPAVNQIETHPF
                     FQRATDQDLMREHGVQHQSWGGFAEGRNDLFTHPVLSEIGKAYDKSAAQVVLRWLIQRS
                     IVTIPKSVSPDRMAQNFDVFDFELTEGQMARIADLDTDTTLFFDHREPEMVAWLSKRRL
                     DS"
     gene            complement(4548..4721)
                     /locus_tag="IE257_RS04140"
                     /old_locus_tag="GCM10010343_08370"
     CDS             complement(4548..4721)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE257_RS04140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010343_08370"
                     /product="hypothetical protein"
                     /protein_id="WP_189964828.1"
                     /transl_table=11
                     /translation="MTKGSRIIEPVDTDQAPLRMVLGSQAPDSTLAVLRKRIDDVETRR
                     DLARSTEFPAGE"
     gene            complement(4791..5162)
                     /locus_tag="IE257_RS04145"
                     /old_locus_tag="GCM10010343_08380"
     CDS             complement(4791..5162)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522676.1"
                     /locus_tag="IE257_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08380"
                     /product="DUF2255 family protein"
                     /protein_id="WP_189964830.1"
                     /transl_table=11
                     /translation="MTDWNAPELETLAAAEELDLSSERPNGTLRDPVTMWVVRSGDRLY
                     VRSVKGTAGPWYRGTQSRHRGRIEAGGVRQDVAFHRAGPDEYPGVDAAYREKYGHHTSI
                     VEHVLTGRARASTLRLEPR"
     gene            <5463..>5663
                     /locus_tag="IE257_RS37815"
                     /old_locus_tag="GCM10010343_08390"
                     /pseudo=""
     CDS             5463..>5663
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049259.1"
                     /locus_tag="IE257_RS37815"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="GCM10010343_08390"
                     /product="transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSRTARPHVRLLLETVRPSPAYVVSRSMDGLAHSPGGLAPYAGIE
                     YWPAGQRNLGRYLFLHPAARRV"
     gene            6072..6842
                     /locus_tag="IE257_RS04155"
                     /old_locus_tag="GCM10010343_08410"
     CDS             6072..6842
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="IE257_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08410"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_189964834.1"
                     /transl_table=11
                     /translation="MSGGTGSARAGAHEPAREGGAEASEGGRPPADFDAFFTAHRPALL
                     ARAVMLCGNRQDAEDAVQDAFLAALENWDRISGYEQPNAWVNLVMRRKLWRMLRLRLRA
                     KRATLDVSLPRQALPDETAQARRVLTAMAALPPRQRMVLVMYSLYAMTHEEIADDLNIA
                     PSTARGNLRKGRDNLRRMLGLDPDTNPLGEVPLVGTGGPAPGDRLAAALSATDSWLCSA
                     FEEDEQAQRQARAGLAGRQGNGNGNGNGNGTGRA"
     gene            6839..8287
                     /locus_tag="IE257_RS04160"
                     /old_locus_tag="GCM10010343_08420"
     CDS             6839..8287
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013594.5"
                     /locus_tag="IE257_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08420"
                     /product="M48 family metallopeptidase"
                     /protein_id="WP_189964835.1"
                     /transl_table=11
                     /translation="MRGTEPTAITSRALLGCALLAGVHLLAVAVLAVQLLLVIAVLSTE
                     TWQIALLGALTVLPVSTLAYGLLAGTSAGVAEGPRIVLTPQQQPELWALTVKLADELGT
                     DPPATIRLADTVNAYAGERGRLLGLIGGPRTLDLGLPLLLGLTADELRGVVCHELGHYA
                     GRHTRLAAVSHRGSVALERTVRYLQFLESDRTTVKPPVRLLLKLTKAYNGIYLRRTLAV
                     RRAQELEADAVAARITGAATFAGALRTVHVLAPFWDGFTADRARPEGSSAPAAGKGGGP
                     LPGVMLPEGVFRDFAHRLADPVGLPFTDGRGEAPARNVVPEDGLGSHPPLEIRLAALCP
                     GGDADNAHRPGARARHCAASLLRDLPELAGALQDAMRPVGGTAPDGGGTTVSMGPPPRR
                     NRSFVRFKVRTTLIGMFLILVASAFVHTVISPPRTDSPPFSPPPTTRNVWPEASPPPPT
                     LPTSVLPPLPSPGRLTPLPLLPVR"
     gene            complement(8444..11455)
                     /locus_tag="IE257_RS04165"
                     /old_locus_tag="GCM10010343_08430"
     CDS             complement(8444..11455)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (74-366). E-value:
                     4.4e-73. Score: 237.8. Matches aSDomain:
                     nrpspksdomains_IE257_RS04165_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PCP (620-681). E-value: 1.3e-15. Score:
                     49.4. Matches aSDomain: nrpspksdomains_IE257_RS04165_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1209: polyketide synthase associated protein papA3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607928.1"
                     /locus_tag="IE257_RS04165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08430"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_189964837.1"
                     /sec_met_domain="Condensation (E-value: 4.9e-55, bitscore:
                     182.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-11, bitscore:
                     40.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 8.1e-10, bitscore:
                     33.9, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDADSVAGDRRQQLQQELLRRARAGTGRRATAGPTAGARAGQD
                     GHAPRDTACSGTTAEPGTPAESDTNVPQTGRVPLSRAQRRMWLMERLGGAGDSYHVPFA
                     TRVRGPFDVAAFATALTRLVARHAILRTRYTEHEGEPCQEVLPTPRTVPVHVVETGATE
                     APELLRRETARPFDLAAGDAVRALVLRHGPQDHTLLLTFHHIAVDGASLETVATELAVL
                     YTAATDGTSGPTLAAAPQYADHARREHDDLPGFEAELNRWSDLLADAAPPRLPRPAAPL
                     ASVRPGAAHSAPLAPAVPEALRALGAQRQATLFAVSLTAAFAALHRLTGDDDLVIGVAG
                     THRSGSAMRGLVGLCVNTLPVRVDVSGDPSFAQLLRRVSDALLEAQHHRHIPFDLVLER
                     LGAGARGADGTALVRVTSDVLGEPTVLRLPGTSTEYVDVPSDGAKFTLSYGLVPGDAAQ
                     PRAIVQYDPNALDDTAAETAVRDYAALLHAVAADPELALSKLPLPGPDDGSGPGDGADP
                     EGDRHPAAQALRAHPSVADATVVRPAQGPPVAYAVLHDSVGPSGHELLGLLRRSLASET
                     VPATVTLLDALPRTAAGPLDRARLPGPPTPNVPSGPRAEAVEEAFAAALGVLPSPDDDF
                     FALGGHSLKAVQLAERLRTDLGLPLTGLDVLQARTPRALTALLEERAARQSAAKAASRP
                     APRSRDIRPGTVLVTGATGGVGAFVVRELAARGRPVLALARPESAHLIATEGVDVIEGD
                     LSDPAGLRDAVAQADAVVHAACTFTRHDVDLAAMEAMVGAWRRGPFVFVSSVDAYGHPG
                     TDRVAEESAPHEPVSPYGRAKLDCEAMVLRAAGTEGRGGASAVRSPLVWGAHDRLREQL
                     RWGAIGTLYQSARQGRPIDLPSPGTDGHAWYGAAWVHAAALARAVAECLDRPVHGVANA
                     CSGHVSWRDLAQDLTELLGTRADFRTTEAVPRDLDHRWHYDSARLARPLRARRGEDRRT
                     VLAEMIGAVPPDKR"
     CDS_motif       complement(9257..9343)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04165_0005"
                     /evalue="5.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE257_RS04165"
                     /protein_end="733"
                     /protein_start="704"
                     /score="22.2"
                     /tool="antismash"
                     /translation="TVLVTGATGGVGAFVVRELAARGRPVLAL"
     aSDomain        complement(9413..9595)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04165_PCP.1"
                     /evalue="1.30E-15"
                     /label="IE257_RS04165_PCP.1"
                     /locus_tag="IE257_RS04165"
                     /protein_end="681"
                     /protein_start="620"
                     /score="49.4"
                     /tool="antismash"
                     /translation="FAAALGVLPSPDDDFFALGGHSLKAVQLAERLRTDLGLPLTGLDV
                     LQARTPRALTALLEER"
     aSModule        complement(9413..11233)
                     /domains="nrpspksdomains_IE257_RS04165_Condensation_LCL.1"
                     /domains="nrpspksdomains_IE257_RS04165_PCP.1"
                     /incomplete
                     /locus_tags="IE257_RS04165"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(10253..10318)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04165_0004"
                     /evalue="7.10E-05"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE257_RS04165"
                     /protein_end="401"
                     /protein_start="379"
                     /score="15.1"
                     /tool="antismash"
                     /translation="DALLEAQHHRHIPFDLVLERLG"
     aSDomain        complement(10358..11233)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04165_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.40E-73"
                     /label="IE257_RS04165_Condensation_LCL.1"
                     /locus_tag="IE257_RS04165"
                     /protein_end="366"
                     /protein_start="74"
                     /score="237.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAVDG"
                     /tool="antismash"
                     /translation="GRVPLSRAQRRMWLMERLGGAGDSYHVPFATRVRGPFDVAAFATA
                     LTRLVARHAILRTRYTEHEGEPCQEVLPTPRTVPVHVVETGATEAPELLRRETARPFDL
                     AAGDAVRALVLRHGPQDHTLLLTFHHIAVDGASLETVATELAVLYTAATDGTSGPTLAA
                     APQYADHARREHDDLPGFEAELNRWSDLLADAAPPRLPRPAAPLASVRPGAAHSAPLAP
                     AVPEALRALGAQRQATLFAVSLTAAFAALHRLTGDDDLVIGVAGTHRSGSAMRGLVGLC
                     VNTLPVRVDVS"
     CDS_motif       complement(10370..10459)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04165_0003"
                     /evalue="1.70E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE257_RS04165"
                     /protein_end="362"
                     /protein_start="332"
                     /score="23.7"
                     /tool="antismash"
                     /translation="DLVIGVAGTHRSGSAMRGLVGLCVNTLPVR"
     CDS_motif       complement(10787..10852)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04165_0002"
                     /evalue="1.40E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE257_RS04165"
                     /protein_end="223"
                     /protein_start="201"
                     /score="20.9"
                     /tool="antismash"
                     /translation="FHHIAVDGASLETVATELAVLY"
     CDS_motif       complement(11054..11164)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04165_0001"
                     /evalue="6.70E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE257_RS04165"
                     /protein_end="134"
                     /protein_start="97"
                     /score="50.7"
                     /tool="antismash"
                     /translation="SYHVPFATRVRGPFDVAAFATALTRLVARHAILRTRY"
     gene            complement(11445..13295)
                     /locus_tag="IE257_RS04170"
                     /old_locus_tag="GCM10010343_08440"
     CDS             complement(11445..13295)
                     /NRPS_PKS="Domain: AMP-binding (24-412). E-value: 2.6e-98.
                     Score: 321.2. Matches aSDomain:
                     nrpspksdomains_IE257_RS04170_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (528-596). E-value: 1.1e-18. Score:
                     59.2. Matches aSDomain: nrpspksdomains_IE257_RS04170_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983226.1"
                     /locus_tag="IE257_RS04170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08440"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_189964839.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-107, bitscore:
                     355.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7e-11, bitscore:
                     38.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTTPQFATPQSAVPTTALPALVARHAELTPDGLAVVDGDTTLT
                     YRRLLQAGHALAAHLRAHEVARGDRVALLTARSSRTVVAQLGLWLAGAVCVPLDPAQPR
                     PRTEAMIADAEVTLTVGDAKLLDAATLPGPVLALPEEPLTSGQPLDESDPDSPAFIMFT
                     SGSTGRPKGVLVPHRAIAELVTAPDYVTLTGRDRVLFHSPMTFDASTFEVWGALANGAA
                     VVVCTEQRPSLEDLARHVERHGVTVAFFTTALFHQLAARRSRVFAQLRSVVVGGEAMAA
                     AQAREVLTAFPWLELVNGYGPTETTTFATAHRVTEQDCEGPIPIGRPISGATVHVLDAD
                     GHPVADGDRGELWIGGSRLAHGYTGLPALTAERFVEHPSAGLRLYRTGDIVSLRPDGIL
                     QFHGRNDDQVKVRGFRIEPAEVEHTLREQPDVADAAVTVDGAGTLEASLVAFVVAAPGP
                     VPHGAALRERLTAVLPAHLVPDTVTVLERLPLTPAGKVDRRALSGRVPSARAHAAEGRP
                     AHGPTGRMTPLEQAVAEVWSQSLGVEVTCAEDEFLLLGGHSLLALAVTDDLREELGVEL
                     SLAEFFAAPTVAAQAALVERALLAAHADLHPETPEHSDVH"
     aSDomain        complement(11508..11711)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04170_PCP.1"
                     /evalue="1.10E-18"
                     /label="IE257_RS04170_PCP.1"
                     /locus_tag="IE257_RS04170"
                     /protein_end="596"
                     /protein_start="528"
                     /score="59.2"
                     /tool="antismash"
                     /translation="EQAVAEVWSQSLGVEVTCAEDEFLLLGGHSLLALAVTDDLREELG
                     VELSLAEFFAAPTVAAQAALVER"
     aSModule        complement(11508..13223)
                     /complete
                     /domains="nrpspksdomains_IE257_RS04170_AMP-binding.1"
                     /domains="nrpspksdomains_IE257_RS04170_PCP.1"
                     /locus_tags="IE257_RS04170"
                     /monomer_pairings="Val -> Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(12030..12095)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04170_0005"
                     /evalue="6.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS04170"
                     /protein_end="422"
                     /protein_start="400"
                     /score="37.4"
                     /tool="antismash"
                     /translation="FHGRNDDQVKVRGFRIEPAEVE"
     aSDomain        complement(12060..13223)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04170_AMP-binding.1"
                     /evalue="2.60E-98"
                     /label="IE257_RS04170_AMP-binding.1"
                     /locus_tag="IE257_RS04170"
                     /protein_end="412"
                     /protein_start="24"
                     /score="321.2"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="ARHAELTPDGLAVVDGDTTLTYRRLLQAGHALAAHLRAHEVARGD
                     RVALLTARSSRTVVAQLGLWLAGAVCVPLDPAQPRPRTEAMIADAEVTLTVGDAKLLDA
                     ATLPGPVLALPEEPLTSGQPLDESDPDSPAFIMFTSGSTGRPKGVLVPHRAIAELVTAP
                     DYVTLTGRDRVLFHSPMTFDASTFEVWGALANGAAVVVCTEQRPSLEDLARHVERHGVT
                     VAFFTTALFHQLAARRSRVFAQLRSVVVGGEAMAAAQAREVLTAFPWLELVNGYGPTET
                     TTFATAHRVTEQDCEGPIPIGRPISGATVHVLDADGHPVADGDRGELWIGGSRLAHGYT
                     GLPALTAERFVEHPSAGLRLYRTGDIVSLRPDGILQFHGRNDDQVKVR"
     CDS_motif       complement(12174..12257)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04170_0004"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS04170"
                     /protein_end="374"
                     /protein_start="346"
                     /score="36.6"
                     /tool="antismash"
                     /translation="GDRGELWIGGSRLAHGYTGLPALTAERF"
     CDS_motif       complement(12624..12656)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04170_0003"
                     /evalue="7.30E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS04170"
                     /protein_end="224"
                     /protein_start="213"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="WGALANGAAVV"
     CDS_motif       complement(12765..12824)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04170_0002"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS04170"
                     /protein_end="177"
                     /protein_start="157"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AFIMFTSGSTGRPKGVLVPH"
     CDS_motif       complement(12999..13040)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04170_0001"
                     /evalue="9.00E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS04170"
                     /protein_end="99"
                     /protein_start="85"
                     /score="9.8"
                     /tool="antismash"
                     /translation="LGLWLAGAVCVPLD"
     gene            complement(13297..15219)
                     /locus_tag="IE257_RS04175"
                     /old_locus_tag="GCM10010343_08450"
     CDS             complement(13297..15219)
                     /NRPS_PKS="Domain: AMP-binding (41-446). E-value: 3.8e-77.
                     Score: 251.5. Matches aSDomain:
                     nrpspksdomains_IE257_RS04175_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (565-632). E-value: 1.3e-12. Score:
                     39.7. Matches aSDomain: nrpspksdomains_IE257_RS04175_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091967.1"
                     /locus_tag="IE257_RS04175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08450"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_189964841.1"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-78, bitscore:
                     259.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-08, bitscore:
                     30.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQSPTAPVIPTTPRTAHLATGSALSIAQGPAAEPTSVVARFEDW
                     ARRTPQAPAVIDGTQIWTYQDLDAAAALVAADLADRVRPGDLVGVCLDRSTALVVTAVA
                     LARLGAVYLPLGPRPGERRIQAVAEDLDVACLIGDPGLLPGEHRSGAHFPLLLPTDGVN
                     APAAAVAAFAGSVRGTRRAPEGALYAVLTSGSTGRPKAVAVAESSLSVALDWYRAETGL
                     APGDRQSLLIGVAFDPHLLELWSALTSGAALVPAPDDTRWDSHLLTDWWRDTALTHAVA
                     ATPTVEPLLDRPWPQDLKLRHLVVGGDRMRRRPGTDVTATVHNAYGPAEATVVTTTHTM
                     RGTDPEAGDQAPPPIGTALPGVTLVVTDGEGRPVARGQEGELRVGGHCLALGYLDPELT
                     ARRFTPPPRELALPAIGRLYRTGDRVRMRADGSLDFLGRLDDQVKISGVRIEPVEVEAA
                     FEQDPRVRTAVVTVLRDSAGHGRLVAHVRPADGAEPVTGDLLAAVRSWLPEQAVPSAVR
                     IVDGFPLDANGKVDRPALAAQAQVPVPPRATTTDDLADATATATASERLVLTTVRELLG
                     RPGIGLGDNFTDAGGTSVVAARLLATVEREAGVRLRAPELLRSTDLRAFAALLDQRRTP
                     RPEGA"
     aSDomain        complement(13324..13524)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04175_PCP.1"
                     /evalue="1.30E-12"
                     /label="IE257_RS04175_PCP.1"
                     /locus_tag="IE257_RS04175"
                     /protein_end="632"
                     /protein_start="565"
                     /score="39.7"
                     /tool="antismash"
                     /translation="LVLTTVRELLGRPGIGLGDNFTDAGGTSVVAARLLATVEREAGVR
                     LRAPELLRSTDLRAFAALLDQR"
     aSModule        complement(13324..15096)
                     /complete
                     /domains="nrpspksdomains_IE257_RS04175_AMP-binding.1"
                     /domains="nrpspksdomains_IE257_RS04175_PCP.1"
                     /locus_tags="IE257_RS04175"
                     /monomer_pairings="Phe -> Phe"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(13852..13917)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04175_0003"
                     /evalue="6.50E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS04175"
                     /protein_end="456"
                     /protein_start="434"
                     /score="31.1"
                     /tool="antismash"
                     /translation="FLGRLDDQVKISGVRIEPVEVE"
     aSDomain        complement(13882..15096)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04175_AMP-binding.1"
                     /evalue="3.80E-77"
                     /label="IE257_RS04175_AMP-binding.1"
                     /locus_tag="IE257_RS04175"
                     /protein_end="446"
                     /protein_start="41"
                     /score="251.5"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="FEDWARRTPQAPAVIDGTQIWTYQDLDAAAALVAADLADRVRPGD
                     LVGVCLDRSTALVVTAVALARLGAVYLPLGPRPGERRIQAVAEDLDVACLIGDPGLLPG
                     EHRSGAHFPLLLPTDGVNAPAAAVAAFAGSVRGTRRAPEGALYAVLTSGSTGRPKAVAV
                     AESSLSVALDWYRAETGLAPGDRQSLLIGVAFDPHLLELWSALTSGAALVPAPDDTRWD
                     SHLLTDWWRDTALTHAVAATPTVEPLLDRPWPQDLKLRHLVVGGDRMRRRPGTDVTATV
                     HNAYGPAEATVVTTTHTMRGTDPEAGDQAPPPIGTALPGVTLVVTDGEGRPVARGQEGE
                     LRVGGHCLALGYLDPELTARRFTPPPRELALPAIGRLYRTGDRVRMRADGSLDFLGRLD
                     DQVKIS"
     CDS_motif       complement(14011..14091)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04175_0002"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS04175"
                     /protein_end="403"
                     /protein_start="376"
                     /score="30.3"
                     /tool="antismash"
                     /translation="GQEGELRVGGHCLALGYLDPELTARRF"
     CDS_motif       complement(14608..14658)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04175_0001"
                     /evalue="5.90E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS04175"
                     /protein_end="204"
                     /protein_start="187"
                     /score="18.9"
                     /tool="antismash"
                     /translation="YAVLTSGSTGRPKAVAV"
     gene            complement(15219..18404)
                     /locus_tag="IE257_RS04180"
                     /old_locus_tag="GCM10010343_08460"
     CDS             complement(15219..18404)
                     /NRPS_PKS="Domain: Condensation_LCL (1-290). E-value:
                     4.9e-64. Score: 208.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS04180_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (462-852). E-value: 1.8e-84.
                     Score: 275.6. Matches aSDomain:
                     nrpspksdomains_IE257_RS04180_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (989-1055). E-value: 6.8e-15. Score:
                     47.0. Matches aSDomain: nrpspksdomains_IE257_RS04180_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850570.1"
                     /locus_tag="IE257_RS04180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08460"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_189964842.1"
                     /sec_met_domain="Condensation (E-value: 1.7e-50, bitscore:
                     167.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.5e-87, bitscore:
                     287.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.4e-10, bitscore:
                     35.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPLSSSQEIVWLHEQMQPGSRAYNFTASLDLWGTLDSEALRRGL
                     DATLARHPGLRLELVVSTGSVPAQRVARQCAPRLRTVDLSTAANPEAAFARLLRTEAET
                     PLDTFQAPLIRWTLVRLAERHHRLIHVEHHLIHDGHSFAILLDDIFRVYRAHVLGETLE
                     LPAAPSYADHVRDRAGAGYAPESLDFWRAELRDQQHDLPLPGLTRPGARRNHHGGQLRQ
                     TIGADLAERLRGHARARGLTPFSTLLGLFAELLRRHSGRSRMVIGTAVGNRPVGYEDAV
                     GMFVNTIPLPLAPDGAAPAQDTMDEVTDTLIRALPHQDVPVQELTRTLGMHTSGADNPL
                     FSVMFSAHDAPLPEIDVPGLDITLFEGFNTGTTRFDLDVVLLPDDRRGVTPRHGSPGMT
                     LVWDYDMDLLGEDVARLLSGRFLDLLRAYLDSPETPLADLVPTVVEPAAEPVPVPADRD
                     PLDPVAAHHPSQPALLCGARRLTYGELDDRVGSLAERLRTAGVTPGRPVAVVLPRGTDS
                     LVALLACLRTGAVYCPLSPSDPPARLGLLLERLAPALVLTGDGTPALPEALPTARIDAP
                     VLPPARGTAELPGTAYVIHTSGSTGTPKPVAVGHAALVHHLTATADRFGLTTSDRVLMF
                     AQPSFDVALEEVLPALHAGACLVLPEHEVPTGAELAELLASARVTVANLPTSYFLATRE
                     DLRPALRDESWAPRLLVLGGERLPVEALRGVLTDTDATVLNVYGVTEAAISSTVHEVSR
                     DALAEGAEIPLGTELPGERIHVLDAHRRPLPSGAVGELAVAGPGLAQGYAGNEEATAAR
                     FVTLDALDGQRVYLTGDLGYRGVDGLLYFLGRRDNQIKLRGHRIELEEIEAAASAALGG
                     RSCAVVLDRENPGGPRLVGFLEDGADGAAFDDKALHAELSRRLPGPLVPARWARLDTMP
                     TLAGGKPDRTALSRRAAALDPDDAATSDAATGSEPGTGHGPGPAATAGSAASDDPMTAL
                     LTEGWRKVLGHGRFDARSHFFHSGGHSLLAAELAAWLEPRLGTRPPLRVLFRNPVLADQ
                     AEALATTTLSTES"
     aSDomain        complement(15240..15437)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04180_PCP.1"
                     /evalue="6.80E-15"
                     /label="IE257_RS04180_PCP.1"
                     /locus_tag="IE257_RS04180"
                     /protein_end="1055"
                     /protein_start="989"
                     /score="47.0"
                     /tool="antismash"
                     /translation="LTEGWRKVLGHGRFDARSHFFHSGGHSLLAAELAAWLEPRLGTRP
                     PLRVLFRNPVLADQAEALATT"
     aSModule        complement(15240..18401)
                     /complete
                     /domains="nrpspksdomains_IE257_RS04180_Condensation_LCL.1"
                     /domains="nrpspksdomains_IE257_RS04180_AMP-binding.1"
                     /domains="nrpspksdomains_IE257_RS04180_PCP.1"
                     /locus_tags="IE257_RS04180"
                     /monomer_pairings="Arg -> Arg"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(15819..15884)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0010"
                     /evalue="5.90E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE257_RS04180"
                     /protein_end="862"
                     /protein_start="840"
                     /score="34.4"
                     /tool="antismash"
                     /translation="FLGRRDNQIKLRGHRIELEEIE"
     aSDomain        complement(15849..17018)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04180_AMP-binding.1"
                     /evalue="1.80E-84"
                     /label="IE257_RS04180_AMP-binding.1"
                     /locus_tag="IE257_RS04180"
                     /protein_end="852"
                     /protein_start="462"
                     /score="275.6"
                     /specificity="substrate consensus: Arg"
                     /tool="antismash"
                     /translation="VAAHHPSQPALLCGARRLTYGELDDRVGSLAERLRTAGVTPGRPV
                     AVVLPRGTDSLVALLACLRTGAVYCPLSPSDPPARLGLLLERLAPALVLTGDGTPALPE
                     ALPTARIDAPVLPPARGTAELPGTAYVIHTSGSTGTPKPVAVGHAALVHHLTATADRFG
                     LTTSDRVLMFAQPSFDVALEEVLPALHAGACLVLPEHEVPTGAELAELLASARVTVANL
                     PTSYFLATREDLRPALRDESWAPRLLVLGGERLPVEALRGVLTDTDATVLNVYGVTEAA
                     ISSTVHEVSRDALAEGAEIPLGTELPGERIHVLDAHRRPLPSGAVGELAVAGPGLAQGY
                     AGNEEATAARFVTLDALDGQRVYLTGDLGYRGVDGLLYFLGRRDNQIKLR"
     CDS_motif       complement(15966..16055)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0009"
                     /evalue="9.90E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS04180"
                     /protein_end="813"
                     /protein_start="783"
                     /score="40.3"
                     /tool="antismash"
                     /translation="PSGAVGELAVAGPGLAQGYAGNEEATAARF"
     CDS_motif       complement(16575..16634)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0008"
                     /evalue="1.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS04180"
                     /protein_end="610"
                     /protein_start="590"
                     /score="23.8"
                     /tool="antismash"
                     /translation="AYVIHTSGSTGTPKPVAVGH"
     CDS_motif       complement(16803..16841)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0007"
                     /evalue="9.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS04180"
                     /protein_end="534"
                     /protein_start="521"
                     /score="12.7"
                     /tool="antismash"
                     /translation="LACLRTGAVYCPL"
     CDS_motif       complement(17367..17480)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0006"
                     /evalue="6.20E-06"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE257_RS04180"
                     /protein_end="346"
                     /protein_start="308"
                     /score="18.5"
                     /tool="antismash"
                     /translation="DTLIRALPHQDVPVQELTRTLGMHTSGADNPLFSVMFS"
     CDS_motif       complement(17535..17612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0005"
                     /evalue="6.80E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE257_RS04180"
                     /protein_end="290"
                     /protein_start="264"
                     /score="28.2"
                     /tool="antismash"
                     /translation="VIGTAVGNRPVGYEDAVGMFVNTIPL"
     aSDomain        complement(17535..18401)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04180_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.90E-64"
                     /label="IE257_RS04180_Condensation_LCL.1"
                     /locus_tag="IE257_RS04180"
                     /protein_end="290"
                     /protein_start="1"
                     /score="208.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLIHDG"
                     /tool="antismash"
                     /translation="LPLSSSQEIVWLHEQMQPGSRAYNFTASLDLWGTLDSEALRRGLD
                     ATLARHPGLRLELVVSTGSVPAQRVARQCAPRLRTVDLSTAANPEAAFARLLRTEAETP
                     LDTFQAPLIRWTLVRLAERHHRLIHVEHHLIHDGHSFAILLDDIFRVYRAHVLGETLEL
                     PAAPSYADHVRDRAGAGYAPESLDFWRAELRDQQHDLPLPGLTRPGARRNHHGGQLRQT
                     IGADLAERLRGHARARGLTPFSTLLGLFAELLRRHSGRSRMVIGTAVGNRPVGYEDAVG
                     MFVNTIPL"
     CDS_motif       complement(17628..17687)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0004"
                     /evalue="6.50E-04"
                     /label="Cy4"
                     /locus_tag="IE257_RS04180"
                     /protein_end="259"
                     /protein_start="239"
                     /score="12.8"
                     /tool="antismash"
                     /translation="GLTPFSTLLGLFAELLRRHS"
     CDS_motif       complement(17853..17876)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0003"
                     /evalue="3.60E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IE257_RS04180"
                     /protein_end="184"
                     /protein_start="176"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="RAGAGYAP"
     CDS_motif       complement(17946..18008)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0002"
                     /evalue="1.70E-04"
                     /label="C3_DCL_135-156"
                     /locus_tag="IE257_RS04180"
                     /protein_end="153"
                     /protein_start="132"
                     /score="14.3"
                     /tool="antismash"
                     /translation="HHLIHDGHSFAILLDDIFRVY"
     CDS_motif       complement(18237..18338)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04180_0001"
                     /evalue="4.00E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE257_RS04180"
                     /protein_end="56"
                     /protein_start="22"
                     /score="22.5"
                     /tool="antismash"
                     /translation="AYNFTASLDLWGTLDSEALRRGLDATLARHPGLR"
     gene            complement(18699..20000)
                     /locus_tag="IE257_RS04185"
                     /old_locus_tag="GCM10010343_08470"
     CDS             complement(18699..20000)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (23-303). E-value:
                     1.5e-23. Score: 75.2. Matches aSDomain:
                     nrpspksdomains_IE257_RS04185_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985947.1"
                     /locus_tag="IE257_RS04185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08470"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_189964845.1"
                     /sec_met_domain="Condensation (E-value: 1.2e-19, bitscore:
                     66.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSITSQYLARYRRLTGDRPDVLLPVTGAQRRFLLVRSLDPAGRP
                     DVVPMFFAFPYGTIDPGRLRAAATRLAARHTALRSRPAVLRGTPVLRVADPDVGVTRPA
                     LEPGESPADALRRAVDSWDAQGPPVRLFLVRDEEREEDILAVVLDHAVCDGRSLARIVD
                     ELGAAYGEEATEPHATPGDTEAELTAYRDAVLRQLAAEERAETPEAAAYWSDRLHALHT
                     HAPAPRPARVPDGAWPSGAAQARLPAHDGGVAFPQLLDACRSAARELYGPGRAVPLGYP
                     WGGRPAGAEPVVGCFLNTLVFPADTGHGPGTEVTADAWWDDLDRADVPFDAVVTAARAA
                     GSGWTGGLDGLLTVDDDSRRPPLVLAGVEGREVHIDGRPVRGPFAVSVTQGAEIRLRMV
                     WDRAVLADETAHRAFDALTHTLTRALSPSEHPVQ"
     aSDomain        complement(19092..19931)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04185_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.50E-23"
                     /label="IE257_RS04185_Condensation_LCL.1"
                     /locus_tag="IE257_RS04185"
                     /protein_end="303"
                     /protein_start="23"
                     /score="75.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DHAVCDG"
                     /tool="antismash"
                     /translation="LPVTGAQRRFLLVRSLDPAGRPDVVPMFFAFPYGTIDPGRLRAAA
                     TRLAARHTALRSRPAVLRGTPVLRVADPDVGVTRPALEPGESPADALRRAVDSWDAQGP
                     PVRLFLVRDEEREEDILAVVLDHAVCDGRSLARIVDELGAAYGEEATEPHATPGDTEAE
                     LTAYRDAVLRQLAAEERAETPEAAAYWSDRLHALHTHAPAPRPARVPDGAWPSGAAQAR
                     LPAHDGGVAFPQLLDACRSAARELYGPGRAVPLGYPWGGRPAGAEPVVGCFLNTLVFP"
     CDS_motif       complement(19095..19175)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04185_0003"
                     /evalue="2.30E-06"
                     /label="C5_DCL_263-294"
                     /locus_tag="IE257_RS04185"
                     /protein_end="302"
                     /protein_start="275"
                     /score="20.1"
                     /tool="antismash"
                     /translation="VPLGYPWGGRPAGAEPVVGCFLNTLVF"
     CDS_motif       complement(19494..19553)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04185_0002"
                     /evalue="2.70E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE257_RS04185"
                     /protein_end="169"
                     /protein_start="149"
                     /score="16.8"
                     /tool="antismash"
                     /translation="HAVCDGRSLARIVDELGAAY"
     CDS_motif       complement(19758..19832)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04185_0001"
                     /evalue="4.30E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="IE257_RS04185"
                     /protein_end="81"
                     /protein_start="56"
                     /score="22.2"
                     /tool="antismash"
                     /translation="GTIDPGRLRAAATRLAARHTALRSR"
     gene            complement(20183..21529)
                     /locus_tag="IE257_RS04190"
                     /old_locus_tag="GCM10010343_08480"
     CDS             complement(20183..21529)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850572.1"
                     /locus_tag="IE257_RS04190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08480"
                     /product="MFS transporter"
                     /protein_id="WP_189964847.1"
                     /transl_table=11
                     /translation="MSDTSRAAAGGPLRLRDFRLLLAGAATGQLGAQVTLVALPLVAVL
                     ELDAPAFQVGLLTAAETAAFLLVGLPAGALTDRMRKRPLMIRADLVRAVAMASIPVAAL
                     ADVLTMAQLYVVALVTGVATVFFDVAHQSYLPQILPRDQLVAGNGALETVRSTAQVTGP
                     GIGGGLVQLVGAHLAVIVDAIGYVLSALFLLRVEQPEETPAPAPAGASLRKEIGEGVRF
                     VFGHPLLRVIALTTGLANFSTAVLMATQTVHLVRVVGLEAGGLGLVLSASAVGGLLGAL
                     CAGRLAAGLGQARVMLLSVLVTGPFALLWPLSGHGLPGAVLFAAGSAVVSFGAVVYNVA
                     QVSFRQGMCPPRLLGRMNATLRFLMWGTLPLGALLGGALAQSYGSRTALAWCAVGILAV
                     PLPLVLSPLRRMRDLPGAQDDGGADRVQGKPRDTASAAGDERPAPAPRA"
     misc_feature    complement(21467..21469)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(21529..21543)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            complement(21888..23033)
                     /locus_tag="IE257_RS04195"
                     /old_locus_tag="GCM10010343_08490"
     CDS             complement(21888..23033)
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042398 - cellular modified amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737048.1"
                     /locus_tag="IE257_RS04195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08490"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_189966109.1"
                     /transl_table=11
                     /translation="MRSVGVEEELLLADADSGEPLAVSGAVLAAADRAATADAADGKES
                     GHTFEAELQEEQVEFGTKPVTEMGELQEEILRWRGEAARHAAEAGAVVAAIGTSPLAVR
                     PSMSPGHRYEWVSRQFGMTAQEQLTCGCHVHVSVESDEEGVAVLDRIRPWLPVLTAMSA
                     NSPFWQGEDTLYGSYRSRVWNRLPTAGPVDVFGSADRYHAEVRAMVESGVLRDTGMIWF
                     DARLSASYPTVEVRVADVCLDASTPVLLAALVRALVDTAAREWRAGDPPARVSTGLLRL
                     ASWQAGRSGLDGPLLHPETLAETEPEAAVDALYRHVADALADSGDAELVRAGIAGLLEH
                     GNGARVQRSLLRSEGDLASVVRHCARRTTAGADRAAPDTRR"
     gene            complement(23212..23757)
                     /locus_tag="IE257_RS04200"
                     /old_locus_tag="GCM10010343_08500"
     CDS             complement(23212..23757)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017242075.1"
                     /locus_tag="IE257_RS04200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08500"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_189964849.1"
                     /transl_table=11
                     /translation="MAGTFQERKLRGMFAAFDADGDGYLREEDFTALVGRWGRLPGVEP
                     GTELRARVEALLMGWWAALLEAGDTNGDGAVDMGELLVLVDRLPTMVADVTATADTVFD
                     AVDSNGDGVISPEEHQRLVETWNGRPADLDGVFELLDPDGDGHLSRERFALLWRQFWIS
                     DDPAEPGNVLCGRIPGPR"
     gene            complement(23966..25924)
                     /locus_tag="IE257_RS04205"
                     /old_locus_tag="GCM10010343_08510"
     CDS             complement(23966..25924)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022822.5"
                     /locus_tag="IE257_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08510"
                     /product="stealth family protein"
                     /protein_id="WP_189964852.1"
                     /transl_table=11
                     /translation="MPLSAPLLPGTLGGSAAAHRHRTPRSYMQGVPRLLLPAGLRRLAR
                     TLRRAGGVPPQPGPAGRERIGGRTPAPSGLTAREEELLATVPGLIHHRGRLATVRDDLL
                     PADARTASLRSVAEALEAAGVPYGLVPDGELVHRVAIAPGDRAAALKACAAALTGLPVY
                     ARLLTADGEAGDVLAEDLPAAVESAESADARGASGAGSGAKDATHTARVRAVRIHQPII
                     TSGRTLSYGPETGCDLEFWEIPDSGEGALAVLRETPYGWWVPSLAASASRRIDDREYPV
                     VDCFSSRFPDDIDFPIDAVITWVDAADPAWRHRRDRAAEAEAGTGRSSGTDRTDRTDGT
                     DGTDGTGGVPGIDLAENRYRDRGELRYCLRSIAAYAPWVRRIFLVTDDQAPAWLAADHP
                     DITVIDHRELSTEPAAPAVFNSHAIESRLHHIPGLAEHFLYFNDDIFLGRPQRPQNYFL
                     PSGLPKVFHDWRAVDPGSRAGDDVFTSSQKVTRQAVEEAVGRTYPHILAHTPYPLTRSA
                     FTRVEELLPGRLAATARSVFRSADDIAPVTLTAHLALAEGHAVEGDLAHTYVSTARRSE
                     IERLPDLAAERGHDAFCLADDEDPDEPDEGGAGGGLSATQQHNVVTAFLEAYFPVPSPF
                     EKSQSTPTGNDSSRPVD"
     misc_feature    25928..25942
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            26119..27813
                     /locus_tag="IE257_RS04210"
                     /old_locus_tag="GCM10010343_08520"
     CDS             26119..27813
                     /NRPS_PKS="Domain: AMP-binding (42-456). E-value: 4.9e-111.
                     Score: 363.1. Matches aSDomain:
                     nrpspksdomains_IE257_RS04210_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742333.1"
                     /locus_tag="IE257_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08520"
                     /product="AMP-binding protein"
                     /protein_id="WP_189964854.1"
                     /sec_met_domain="AMP-binding (E-value: 4.8e-117, bitscore:
                     386.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGARWPSSPQRVQEVRVSLASSRASGSSEVPLLRETIGDNLDRT
                     VRRFPGRDALVDVAAGRRWTYAELAADVDALALGLLDLGIVRGERVGIWAPNRAEWTLV
                     QYATAKIGAILVTVNPAYRSHELEYVLGQSGIRLLVAAERFKSSDYAAMVEEVRPRCPG
                     LEFTVLFDGPRWDALLERGRGADPAALARAQAALSPDDPINIQYTSGTTGFPKGATLSH
                     HNILNNGFFVGELCGYGEHDRVCIPVPFYHCFGMVMGNLACTSHGAAMVIPAPAFDPAA
                     TLAAVEAEACTSLYGVPTMFIAELAAPGFDGYDLSSLRTGIMAGSPCPVEVMTQVIERM
                     GMAEVSICYGMTETSPVSTQTRVDDSVERRVSTVGRVGPHLEVKVVDPQSGRTVPRGTP
                     GELCTRGYSVMLGYWGEPEKTAEAVDPEGWMHTGDLAVMDGDGYLSITGRIKDMVIRGG
                     ENLYPREIEEFLHAHPDVMDVQVIGVPDPKYGEELMAWVRMREGAEPLTAQAVRAYCAG
                     RLAHFKIPRYVHVVEEFPMTVTGKIRKIEMRAMATRLLEEGAASGGA"
     aSDomain        26245..27486
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04210_AMP-binding.1"
                     /evalue="4.90E-111"
                     /label="IE257_RS04210_AMP-binding.1"
                     /locus_tag="IE257_RS04210"
                     /protein_end="456"
                     /protein_start="42"
                     /score="363.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DRTVRRFPGRDALVDVAAGRRWTYAELAADVDALALGLLDLGIVR
                     GERVGIWAPNRAEWTLVQYATAKIGAILVTVNPAYRSHELEYVLGQSGIRLLVAAERFK
                     SSDYAAMVEEVRPRCPGLEFTVLFDGPRWDALLERGRGADPAALARAQAALSPDDPINI
                     QYTSGTTGFPKGATLSHHNILNNGFFVGELCGYGEHDRVCIPVPFYHCFGMVMGNLACT
                     SHGAAMVIPAPAFDPAATLAAVEAEACTSLYGVPTMFIAELAAPGFDGYDLSSLRTGIM
                     AGSPCPVEVMTQVIERMGMAEVSICYGMTETSPVSTQTRVDDSVERRVSTVGRVGPHLE
                     VKVVDPQSGRTVPRGTPGELCTRGYSVMLGYWGEPEKTAEAVDPEGWMHTGDLAVMDGD
                     GYLSITGRIKDMVIR"
     CDS_motif       26731..26784
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04210_0001"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS04210"
                     /protein_end="222"
                     /protein_start="204"
                     /score="17.8"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGATLSH"
     CDS_motif       27301..27387
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04210_0002"
                     /evalue="5.50E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS04210"
                     /protein_end="423"
                     /protein_start="394"
                     /score="31.5"
                     /tool="antismash"
                     /translation="PRGTPGELCTRGYSVMLGYWGEPEKTAEA"
     gene            28213..29883
                     /locus_tag="IE257_RS04215"
                     /old_locus_tag="GCM10010343_08530"
     CDS             28213..29883
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522854.1"
                     /locus_tag="IE257_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08530"
                     /product="cytosine permease"
                     /protein_id="WP_189964856.1"
                     /transl_table=11
                     /translation="MSTTESRHTTTDTTKTAADQAVKETLEDYTLRFAPRSYRRWTPMV
                     VATTALGGIAYMADFSIGAGIGLAHGTGNALVAITVAAVVIFITGFPLAYYGARYNIDL
                     DLITRGSGFGYYGSVLTSIIFASFTFIFFALEGSIMAQGLELGLGLPLWLGYAVSTLMV
                     IPLVVYGMKALSKLQVWTTPIWLLLMVGPLVYLIANDPGTVDRFLAYPGTTGDGAVNTA
                     SVMLGAGVCLSLIAQIGEQIDYLRFMPPKTAANKRSWWTAVVMAGPGWVVLGALKQAIG
                     VFLAVHIIAEVGPAAAPEPIQQFRSAFDAMMPGWLVVPLAVVLVVISQIKINVTNAYSG
                     SLAWTNSFTRVTGHYPGRMIFVLVNLAFALALMEADMFSFLGSILGFYSNCAIAWVVTV
                     ATDIGINKYVLKLSPLQPEFRRGMLHAVNPVGVVAFVAASGLSIAMYFHALGDTLQPYS
                     PVAAAVIAFAVTPLMAVVTKGRYYVRRADDGIGEPLLDTDGNPSGVTLDCHVCRQSYER
                     PDVTACVTHGAVVCSLCLSTDRGGDHVLPAAEPRAADRH"
     gene            complement(29987..30196)
                     /locus_tag="IE257_RS04220"
     CDS             complement(29987..30196)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484973.1"
                     /locus_tag="IE257_RS04220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="I78 family peptidase inhibitor"
                     /protein_id="WP_189964858.1"
                     /transl_table=11
                     /translation="MTASASSPGADDPAHYTGLDTGEAKRRALAHGWTTVRTVAPGTML
                     TMEYVEGRLNLEVEDGRVRRAWSG"
     gene            complement(30285..31649)
                     /locus_tag="IE257_RS04225"
                     /old_locus_tag="GCM10010343_08550"
     CDS             complement(30285..31649)
                     /NRPS_PKS="Domain: AMP-binding (14-363). E-value: 1.1e-71.
                     Score: 233.5. Matches aSDomain:
                     nrpspksdomains_IE257_RS04225_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740919.1"
                     /locus_tag="IE257_RS04225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08550"
                     /product="AMP-binding protein"
                     /protein_id="WP_189964860.1"
                     /sec_met_domain="AMP-binding (E-value: 4.3e-74, bitscore:
                     245.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTALTGVFGDRADAVSVAGRTASYEELLGAAGAVAADLAALGPV
                     RAFAVTATASLETVAAVVGGLLAGVPCVPLPPDAGPAERDHILRDSGARLIEVDFARRA
                     PAASAAPTAQAAGPEDPALILYTSGTTGAPKGVVLSAAAITADLDALAAAWEWSAQDTL
                     VHGLPLFHVHGLVLGVLGALRTGSRLVHTGRPTPEAYAEAAAAGGSLYFGVPTVWSRIA
                     AAPQAAAALSRARLLVSGSAALPTPVFRDLERLTGHRPVERYGMTETLITLSGRAGGEV
                     RPGAVGTPLTGIRTRIAAEPGAEIGELQLVGPTLFSGYLGRPEATAAAFTEDGWFRTGD
                     IAAVDGDGVHRIVGRASTDMIKSGGYRIGAGEIENALLDHPRVQEAAVIGVPDADLGER
                     IVAFVVADGVSGAELTDFVATHLSVHKRPREVRFIAAVPRNAMGKPQKRLLLAGE"
     aSDomain        complement(30561..31607)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE257_RS04225_AMP-binding.1"
                     /evalue="1.10E-71"
                     /label="IE257_RS04225_AMP-binding.1"
                     /locus_tag="IE257_RS04225"
                     /protein_end="363"
                     /protein_start="14"
                     /score="233.5"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="AVSVAGRTASYEELLGAAGAVAADLAALGPVRAFAVTATASLETV
                     AAVVGGLLAGVPCVPLPPDAGPAERDHILRDSGARLIEVDFARRAPAASAAPTAQAAGP
                     EDPALILYTSGTTGAPKGVVLSAAAITADLDALAAAWEWSAQDTLVHGLPLFHVHGLVL
                     GVLGALRTGSRLVHTGRPTPEAYAEAAAAGGSLYFGVPTVWSRIAAAPQAAAALSRARL
                     LVSGSAALPTPVFRDLERLTGHRPVERYGMTETLITLSGRAGGEVRPGAVGTPLTGIRT
                     RIAAEPGAEIGELQLVGPTLFSGYLGRPEATAAAFTEDGWFRTGDIAAVDGDGVHRIVG
                     RASTDMIKS"
     CDS_motif       complement(30660..30737)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04225_0002"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="IE257_RS04225"
                     /protein_end="330"
                     /protein_start="304"
                     /score="30.3"
                     /tool="antismash"
                     /translation="IGELQLVGPTLFSGYLGRPEATAAAF"
     CDS_motif       complement(31230..31286)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE257_RS04225_0001"
                     /evalue="9.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="IE257_RS04225"
                     /protein_end="140"
                     /protein_start="121"
                     /score="24.4"
                     /tool="antismash"
                     /translation="ALILYTSGTTGAPKGVVLS"
     misc_feature    31795..31806
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            31799..32404
                     /locus_tag="IE257_RS04230"
                     /old_locus_tag="GCM10010343_08560"
     CDS             31799..32404
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021505.5"
                     /locus_tag="IE257_RS04230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08560"
                     /product="DUF2231 domain-containing protein"
                     /protein_id="WP_189964862.1"
                     /transl_table=11
                     /translation="MNTHIDDGTPHSGRVPALDKTSERWLGAVATVEESTALDPAIRAL
                     QRGIRGLPLGALRGLLRGEPLGHPAHPMLVQVPMGCWLSAAVLDTVPGAHRYATVLTAV
                     GLAGVAPAAAAGWADWAELPPRQARVGVAHALANAAAVGCYAVALSDRLRGRGARGRLW
                     SLAGLGAAAVSGALGGHIAYGDRMERGGTGNDIPPGIA"
     gene            32505..32723
                     /locus_tag="IE257_RS04235"
                     /old_locus_tag="GCM10010343_08570"
     CDS             32505..32723
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE257_RS04235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010343_08570"
                     /product="hypothetical protein"
                     /protein_id="WP_189964864.1"
                     /transl_table=11
                     /translation="MEDQGGAGGAPLHDHDDEQSRRRTPHVAPRSAAPGKDVPPVRRAD
                     TDEASRLDRPGDDGESPRERRRPGREH"
     gene            complement(32815..34326)
                     /locus_tag="IE257_RS04240"
                     /old_locus_tag="GCM10010343_08580"
     CDS             complement(32815..34326)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743002.1"
                     /locus_tag="IE257_RS04240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08580"
                     /product="glutamate synthase subunit beta"
                     /protein_id="WP_189964866.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.7e-24, bitscore:
                     81.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDPFGFLRIPREAVPARPVEERLGDWREVHAGRALLPLVSRQAD
                     RCMDCGIPFCHTGCPLGNLVPEWNAYAAHGDWRAAYERLHATNNFPEVTGRLCPAPCED
                     ACVLAINADPVTIKNVEQTIADEGLRRGFMMPRPPERHSGKTVAVIGSGPAGLAAAQQL
                     TRAGHRVTVHERADRIGGLLRYGIPEFKMEKVHLDRRIEQMRAEGTVFATGADVGGAAG
                     AGADELRSGCDAVVVAIGAGERRELPVPGRSLQGIHQAMDYLTCANRVREGDYPVSPLT
                     AEGRRVVIVGGGDTGSDCLGTALRQGATSVLQLDINPEPGTGRTDDEPWPVYPRTYRIS
                     HAHEEARGRADRDPRLFACATLRFEGDEEGRVRALHLTAVEPVARSPLAGTEQVIPVGL
                     VLLALGFSGPERAGGLREQLGLALDERGNFARDAGFAADAGRAPGVFVAGDAGRGQSLV
                     VWAIAEGRAAAAAVDRYLTGSTCLPAPVAAHDRPMTALGRMRYGP"
     gene            34659..35294
                     /locus_tag="IE257_RS04245"
                     /old_locus_tag="GCM10010343_08590"
     CDS             34659..35294
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007261854.1"
                     /locus_tag="IE257_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08590"
                     /product="VOC family protein"
                     /protein_id="WP_189964868.1"
                     /transl_table=11
                     /translation="MRLDHVSYAVARDSFVSTVQWIGSALGAGFVDGGVHPRFGTRNFI
                     LPLSGGTYVEVVTTLDHPAADRAPFGQAVARRAAEGGGWLGWVVSVDDIAPVEARLGRT
                     SAEGHRVRPDGFDLRWKQIGLLELLEAPQLPYFLQWLVPTEERPSADPRTSTTIHGVSI
                     AGDAASIAEFLGEPADHPLDQIDVTWAEDEEPGLVSVEFATAHGPVTI"
     gene            <35207..35598
                     /locus_tag="IE257_RS04250"
                     /pseudo=""
     CDS             <35207..35598
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377534.1"
                     /locus_tag="IE257_RS04250"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="PDRRHLGRGRGTGPGLGRVRHRPRPGHDLTRARLPHGSSRPVRRR
                     TLLRSGHGPHPRATKRARQAPNPAVGRARGPGPLPRAIRSHLRRASNAASTASSSGAAA
                     PHDATNSPSPTRQHSTSPPSSSGHDA"
     gene            complement(35614..36759)
                     /locus_tag="IE257_RS04255"
                     /old_locus_tag="GCM10010343_08600"
     CDS             complement(35614..36759)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606596.1"
                     /locus_tag="IE257_RS04255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08600"
                     /product="glycoside hydrolase family 64 protein"
                     /protein_id="WP_229920195.1"
                     /transl_table=11
                     /translation="MAVAAGLMVFGPSPSAEAVPATIPLTIKNSSGRSEPVYVYNLGTL
                     LTTGQQGWADANGTFHPWPVGGNPPTPAPDASITGPANGQTKTIRMPKFSGRIYFSIGQ
                     KIVFKLTTGGLVQPAVQNPADPNRNILFNWSEYTLNDAGLWINSTQVDMFSAPYAVGVK
                     AANGAVSTTGRLKPGGYNAVFSQLRSAGWGGLIQNRPDGTPLRALSPGHGIEAGGIPAG
                     VMNDYINRVWNKYGSSTLTVTPFANQPNTKYYGRVSGNVMNFTNGSGAVVTSFQKPDSD
                     SVFGCYKLLDAPNDQVRGPISRTLCAGFNRSTLLTNPGQPDPNNANFYRDAVTNHYSRI
                     IHGQMADGKAYGFAFDDVGAHESLVHDGNPQEAFMTLEPFN"
     misc_feature    complement(36882..36896)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.16"
                     /tool="antismash"
     misc_feature    36883..36897
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.03"
                     /tool="antismash"
     gene            37038..38012
                     /locus_tag="IE257_RS04260"
                     /old_locus_tag="GCM10010343_08610"
     CDS             37038..38012
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743192.1"
                     /locus_tag="IE257_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010343_08610"
                     /product="5'-nucleotidase"
                     /protein_id="WP_189966111.1"
                     /transl_table=11
                     /translation="MRYDLSHRLVVGIASSALFDLTDCDTVFREEGEDVYRTYQATHAD
                     NVLGKGVAFPFVRRLLSLNDLSEQSDPLVEVIILSRNDPDTGLRVMRSIKAYDLPISRA
                     VFRQGRPSHRFMPALNMSLFLSANGPDVRDAVADGLPAGHVLRTARIDDETDPELRMAF
                     DFDGVVASDTAERIYQSGGIDEFRAYEVRNAAAPHDPGPLRDFLAGINRVQRLEEDRRR
                     TDPTYRPRLRVSLVTARDAPAHERALLSLKEWGLRVNDAFFLGGIEKAAVMKALDPHIF
                     FDDQVAHLNGTAQGTPSVHIPFGVVNATPPASRRGSPDQGHTT"
ORIGIN
        1 catcgaggac gaagcccgcg gcggaaccaa tgctgaaatc atcgaccgcg ccccgaccca
       61 ggaacccgcc cagttcaaca gaccactcca cataccacta cagcactccc aacccaccat
      121 cacggcagcg gcccagaccg tggacgacca gcagttcagc ccacagccgg cacaccgtga
      181 gatcaacacc gatgggatgg gccagttgct tccgcccatc ctgttgctcg atcacgccgg
      241 cgagtacgag actcgtcgct cctgcatcga ggtagttacc agcgatgctc cgcaggtttc
      301 gcaggtttcg cagcagcatg tcgaaggtga aacggtcatc cggaggagag ggccagaact
      361 gcctcagcca gtcaaggtcg agcacggcat gagggacccc gccatcggcg aggaggtcgc
      421 cccccgcctc ggcaacggtg gtttccccca cgcctacgat gccattgatc aggagagccc
      481 gagctccccg ggggctgcct gagggcatct cggcatccta cgtcgagacg cgaacctccg
      541 atgtgcgctc aagtccgcag ccacccacgt ccaaagcgtg cgcatcgcta cgccaaggca
      601 gccgcccgtc cgagcaccac aaccgggcag ccggagctga cggaatggcc ggggcactgc
      661 catcggccgg cgaggacgcg gagctcgcag ccggccgcct ctcgaggtgg ccccgtcggt
      721 ggcccggggc acgcggtggt gtcagcggac aggcgggagg tgggtcacag ggatccgacg
      781 accttgcggg gggtgatacg cacgacgacg cgttcgttgt cctcggccga cgccggattg
      841 aaatcggcgt atgccttgcc cgtgtacttg cgcgacaacg cgtcgatcaa ctcctgcccg
      901 ccctccgtcg tcaaccgcgc cgtcccgcgg atctccgcat acgtatacgg agcatcactc
      961 ggattcacca acacggtgac acgaggatca cgccgcagat tccgctcctt acgacgcccc
     1021 accgtcgtcg acaccaacag gtcatcacca tctcgcgcca accacgtcac agacacctgc
     1081 ggactgccat caggctggat cgtcgcaacc gaggcgaaaa ccggagtgtc gtcaatgact
     1141 ttcctcagct cctcggagag cacaaccgac acggtcgaat cctttcccgg ctgggtaccg
     1201 ccatcatcgg gtgagcggcg acaacaccat gcgtaaacca cccgcacctg acaaaccgga
     1261 aaccgcgccc gccctacgcc gctccgaacg cgaaatcatc cgaacagccc acgccaccca
     1321 ccgggggcag ggacggacct cggcctgcga gtccggccca tccggaagga ggacacacaa
     1381 cccctgagcc ggatgagcac tccccgctcc agcaggcgcc tgcaggacta cccggtcgac
     1441 cggccgccct ctcggccggc ttccgttcgc agtttgcgag cccgctcggc cgggtcgcaa
     1501 ttcggaccga cgccctcgat cagcaccaca tcaccctcca cgtggtccgt acgcaaacgc
     1561 agaatggccc ggtaggcggg agagtcgtac caggcacggg cctcggccag accgggaaac
     1621 tcgatcagca ccatgctgcc gggccactcg ccctccacga cttcgaccgg cggaccgtgg
     1681 atcacgaacc gaccggcgaa agggtccagg gtcgcctgga tgcgctccag gtactcgaga
     1741 atgtcggagt gattccggcg gctgcggaga tgcgcgaaac cgtaagcgga caccacaggt
     1801 ctcccttcgt tctgtgcctg tgagcgacga ccagaacgta gccgcggacg gctcggcagc
     1861 acgattacct ccggtgtaat cgccgagggc acacaccaag ccgccgccgg gccgggcggg
     1921 ctccagaccg gcgggccggc gttgtgtgtc atggaggtag atcggcggcg ccggaaactc
     1981 gtatgacaag gcggcgagcc tttgccacga tcgccgagtt gtcccgcacg cccagccccg
     2041 ttcttggagg aacaccacgg ccatcaatta cgacctcgct ccacgccggt tgccgtggtc
     2101 tgccgtcgat cccgacctca ttgccttctc gtgggacgat gcgcagagct ctgaaatcgc
     2161 cgcagtgatc gcctcgatgg tgccccccgc cggtgccggg tgggaagaac aacatcgctt
     2221 caccaccgag gtcaccgcac tcctcgcagc ccgatacggc cggtgggtct gcggatggca
     2281 ttgggcggtt ggcgagggcg gcggcggtgg cgtcgtcacc agctggtgct gcacctccca
     2341 ttcgatcggt gaacccgcag agacggctgc cagggtgatc gcgtcgctgc tggagtggcg
     2401 cgactggctg gaggagctgg ccgagaagtt cgcccggttg gcgccgcccg ccggagcgga
     2461 cgccgagggc cgcagctggc acctggaacg ggcggctacc cgactcgtga cggtggtagt
     2521 ggaccgcacg ggtgccgaat gcggttggta cgggctctgc cacacggtgc tgacgtggtt
     2581 cctctcttcc acgggcatgg ggccggaacg tgcgaaggac gcggtcgaga ccgcaatcgg
     2641 aggacggttc aagagctgga cggagccacc gcggcgcctg gtcgacgccg tgggagagga
     2701 tcttgccgtg gggctgaccg gagagctgcc gtaccgtgac cgctgacgct ctggctgcct
     2761 ggtgccacgt caggagccag gtggactggg cttccgcggc cggtgagacg ccggctccgg
     2821 tcgaggcggc catggacggc ctcgttgcct ggtgcgatgc gggaggccgg gcctcggatc
     2881 cggcacgagc cgaccggttg ctcgcggcgg tggcccagtc gcgcgccgac gcctcccaca
     2941 agcggcccct cacctgcgcg cttctcactg aatggcagca gcttgtcctc ggtctgcccg
     3001 gggttgagtt ccgacagggc gatgccttcg ccaagggtgg cagggaacgc tacgcactta
     3061 cgccacacac ccggcgggac ttcgagcggt gcctgcgcga cagtgccgac ctgcgggtcc
     3121 ccttggcctc ccgcgcggcc agggcctacc tggacgtggc cttcttccac cccttcgacg
     3181 acggcaacgc ccgcctggcc atgctcaccc tcgcccatgt actggagctg gagggagtcc
     3241 ggctggatcg gaccggcccc ttgcagacca cgcgatacgc ggacgacgct gccggcgcag
     3301 cagacctggc agtccttgtc tccgtcctca tccggtcgac ccatcagcgg gcggccagag
     3361 cccggccctg aggccgcctc gcacccggct ctcctgatca gtccggccgt ctctccttcg
     3421 cggggagagg tcagtgggcg cgggtgcgcg gggcgttgta ctgctcgtcc gtgatgtgct
     3481 ccagccaggt ggtctcgggc cgctcggcgt cgggtgcggt gccgtcccgc agagcgaggt
     3541 gctgcatgaa ccggctgccc ggaccttctc ctgccgggtt gaactcgcgg tggccgctgc
     3601 tgcggtggcc ggcgttcagc tgtccaggcg gcgcttgctg agccaggcga ccatctcggg
     3661 ctcgcggtgg tcgaagaaca gcgtcgtgtc ggtgtccagg tctgcgatcc gtgccatctg
     3721 gccctcggtg agttcgaagt cgaagacgtc gaagttctgc gccatccggt cggggctgac
     3781 cgacttcggg atcgtgacga tgctccgctg gatcagccag cggagcacga cctgggccgc
     3841 ggacttgtcg tacgccttac cgatctcgct caggacgggg tgcgtgaaca agtcgttcct
     3901 gccttcggcg aagccgcccc aggactggtg ctggaccccg tgctcccgca tcaggtcctg
     3961 gtcggtggcg cgctggaaga aggggtgggt ctcgatctga ttgaccgccg gggcgatctc
     4021 gttgttgagg atgaggtcca ggagccggtc ggggtagaag ttggcgaccc cgatcgcctt
     4081 ggccaggcct tctcggcctg cggcctccat cgcgcgccac tggccgtaca cgtcgccgta
     4141 gggctggtgc atcaggtaca gatcgacgtg gcccaggccc agcttggtca gggacgtctc
     4201 cagggcgcgg cgggtgttct cctcggcggg tgcgtcctgg atccacagct tggtggtgac
     4261 gaacagctct tcgcgcggga tcccgctgtt cttgatggcc cgaccgacgg cctcctcgtt
     4321 gccgtaggcg gccgcggtgt cgatgagccg gtatccggcg gcgagggcgt cggcaacggc
     4381 ctgctcggtc tgctccggcg ggatctggta gacgccgaag ccgaggatcg gcatcccgat
     4441 gccgttgttc aaggtgacgg tctgcatggg atctccatat tgctcgggtg cgtggcaggc
     4501 agcggccgga cgtgcgccgg cctgctgccg cccggtcggt ggggtggtca ctctccggcg
     4561 gggaactccg tggaccgtgc caggtcgcgc cgggtctcga cgtcgtcgat ccgcttgcgc
     4621 agcacggcga gggtggagtc cggcgcctgc gagccgagca ccatccgtag cggcgcctgg
     4681 tcggtgtcga cgggttcgat gatgcggctg cctttcgtca ccgctgcggt ggctgtgtca
     4741 gctggaggga cgccggtggg agtggggtcc gggcccggag tccgggctgt tcaacgcggt
     4801 tcgaggcgca gggtcgaggc tcgggcacgg ccggtcagga cgtgctcgac gatgctcgtg
     4861 tggtgcccgt acttctcccg gtaggccgcg tccacgcctg ggtactcgtc ggggccggcg
     4921 cggtggaagg cgacgtcctg acggacgccg ccggcttcga tgcgtccccg gtggcgggac
     4981 tgcgttcccc ggtaccaggg gccggccgtg cccttgaccg agcggacgta cagccggtcg
     5041 ccggagcgga ccacccacat cgtcaccggg tcgcgcaggg tgccgttggg ccgttcggat
     5101 gacaggtcca gctcctcggc cgcggcgagc gtctccagct ccggggcgtt ccagtccgtc
     5161 atcgccattc ctttccgctg tgcgaggccg ggagccggag ctccgaccag ccgtgtcggc
     5221 gttcaccacg tccaccgttc cccgcacgcg aggggcgcgc catcggagcg ggccggacca
     5281 cccgggatcc ggtcgaccgc cgcccgggac acggtgcgac acgacgcgac acggtcaccg
     5341 tgccccctcc cggccgccgc aggcaggccg ggctgtgtca gggggtgatg agcgggggtg
     5401 tgacagggcc tcctccagac gcataccgca ccggcggcgg agtgacgcag gcggggtggc
     5461 atccgagccg cacagcgcgc ccgcacgtgc ggctcctgct ggaaacggtg cgcccgagcc
     5521 ccgcctacgt ggtcagccgc agcatggacg gcctggcgca cagtcccggc ggtctcgccc
     5581 cgtacgcggg catcgagtac tggcccgccg gtcagcgcaa cctcggccgc tacctcttcc
     5641 tccaccccgc cgcccgccgg gtgctcgaca tgaccgccac ccgcaccgag tccacgccgt
     5701 cccggcagga gccgtaggcc ccccggaaag ttcttcggcc gacgggtaaa cgcgcagccc
     5761 tgccacgggt gttcagcggt gtcgcagtcg gcagagcttc tgccgacgtt acgtggtcgg
     5821 caggggacgt ggtcggatat gtgggaatca gtggtgtttg cggcactggc cgctacggtg
     5881 aggatcaccc tccaggtggt ggcctggcgc cgggagttgg cccgtgaacg tgaacgggtc
     5941 cggctggtgc tcgaagcggt acgtctggcg ggtcacggtg tccaggtgga ggaccgccgg
     6001 tcggacgggg gtgtcctgat cgtgcggggt gatggcctgg ccgcgtcgac cggccaagag
     6061 ggtgaggcac gatgagcggt gggacgggca gtgcccgggc gggtgcgcat gagcccgccc
     6121 gggagggtgg cgcggaggca tcggagggcg ggcgtcctcc ggccgacttc gacgcgttct
     6181 tcacggctca tcgtccggcg ctgctggcac gggcggtgat gctgtgcggc aaccgtcagg
     6241 acgcggagga cgccgtccag gacgccttcc tcgccgcgct ggagaactgg gaccggatca
     6301 gcggctacga gcagccgaac gcgtgggtga atctggtgat gcggagaaaa ctgtggcgca
     6361 tgctgcggct gcgcctgagg gcgaagcgcg cgacgctgga cgtgtccctg ccccgccagg
     6421 cccttccgga cgagacggcg caggcccgac gggtgctgac cgcgatggcc gcactgccgc
     6481 cgcgccagcg gatggtgctg gtcatgtaca gcctctacgc catgacccac gaggagatcg
     6541 ccgatgacct gaacatcgcg ccctccacgg cacgagggaa cctccgcaag ggacgcgaca
     6601 acctccggcg catgctcggt ctcgacccgg acaccaatcc tctgggtgag gtgccgctgg
     6661 tgggaaccgg tggccccgcg cccggggacc ggctcgcagc ggccctgagc gccaccgact
     6721 cctggctctg ctcggcattc gaggaggacg aacaggcaca gcggcaggcc cgggcgggcc
     6781 tcgccggccg ccaaggcaat ggcaatggca atggcaacgg caacggcacg gggcgcgcgt
     6841 gagagggacg gagccgacgg cgatcacatc gcgtgccctg ctcggctgcg cgctgctggc
     6901 cggggtccat ctgctcgccg tcgccgtcct ggccgtccaa ctcctgctgg tcatcgccgt
     6961 cctgagcacg gagacctggc agatcgccct gctgggcgcc ctcaccgtgc tccccgtgtc
     7021 cactctggcc tacggcctgc tcgccggtac gtccgcgggc gtggccgaag gtccccggat
     7081 cgtgctgacc ccgcagcagc agcccgaact gtgggctctg acggtgaaac tcgccgacga
     7141 gctgggcacc gacccacccg cgacgatccg cctggccgac accgtcaacg cctacgccgg
     7201 cgagcgcggc aggcttctgg gcctgatcgg gggtccccgc acgctggacc tgggtctgcc
     7261 gctgctcctc ggcctcaccg cggacgagct gcgcggcgtc gtgtgccacg aactggggca
     7321 ctacgcgggc cggcacaccc ggctggctgc cgtcagccac cgcggcagcg tcgccctgga
     7381 acgcacggtc cgctacctgc agttcctgga atcggaccgg accaccgtca aaccgccggt
     7441 gcggctgctc ctgaagctca ccaaggcgta caacggcatc tatctgcgcc ggaccctggc
     7501 cgtacggcgc gctcaggagc tcgaggcgga cgccgtggcg gcccggatca ccggggcggc
     7561 cacgttcgca ggggctctac ggaccgtgca cgtcctggca ccgttctggg acgggttcac
     7621 cgcggaccgg gcccggccgg agggatcgtc ggcgcctgcg gccgggaagg gcggcgggcc
     7681 tctgcccgga gtgatgctgc ccgagggcgt gttccgggac ttcgcccacc gactcgccga
     7741 tccggtgggc ctgcccttca ccgacggcag gggggaggcc ccggcacgga acgtcgtccc
     7801 cgaggacggg ctcggcagtc acccacctct ggagatccgg ctggcggcgc tgtgccccgg
     7861 cggcgacgcg gacaacgccc accggccggg cgcgcgcgca cgtcattgcg ccgcgagcct
     7921 tctgcgggac cttcccgagc tggccggggc cttgcaggac gcgatgcgcc cggtcggggg
     7981 cacggcgccc gacgggggcg gcaccactgt gtccatggga ccaccgcctc ggcgcaacag
     8041 gtccttcgtc cggttcaagg tcagaacgac gctgatcggg atgttcctga tcctggtggc
     8101 gagtgcgttc gtccacacgg tcatctcccc gccccgcacc gattctccgc cgttctcccc
     8161 accgcccacc acgcggaacg tgtggccgga ggcgtcgccg ccgcctccga cacttccgac
     8221 gtccgtgctc ccacctctcc cgtcgcccgg ccggctcacc ccgctgccgc tcctgccggt
     8281 gaggtagtcg gccgaatcga cgggccgcgg tgggcaggag ccggggtgcc caccagcagg
     8341 ccgtgctccg tcgggcggca gaagcggcgg tgcgggcggg ctgccccgca ggagccccgg
     8401 agccccggag cccccgcagg aggctccgga cgcaggcggc gtgtcagcgc ttgtcgggtg
     8461 gcacggcgcc gatcatctcc gccagtacgg tccgccggtc ctcgccccgg cgggcgcgga
     8521 gcggacgggc caggcgggca ctgtcgtagt gccagcggtg atcgaggtcc cggggaaccg
     8581 cttcggtcgt acggaagtcc gcgcgggtgc cgagcagttc cgtgaggtcc tgcgccaggt
     8641 cacgccagga cacatggccg ctgcacgcgt tggcgactcc gtgcacgggc cggtccaggc
     8701 actcggctac cgcgcgggcc agggcggccg cgtgcaccca ggcggcgccg taccaggcgt
     8761 gtccgtcggt accggggctc ggcaggtcga tcggtcggcc ctggcgggcg gactggtaga
     8821 gcgtgccgat ggcgccccag cgcagctgtt cgcgcagccg gtcgtgcgcg ccccagacga
     8881 gcggtgaccg cacggcgctc gctcccccgc gtccctcggt ccccgccgcg cgcagcacca
     8941 tggcttcgca gtcgagcttg gcccttccgt acgggctcac gggctcgtgg ggtgcggact
     9001 cctcggcgac ccggtccgtc ccggggtgac cgtaggcgtc gacgctgctg acgaagacga
     9061 acggtccgcg ccgccaggca ccgaccatcg cctccatcgc tgccaggtcc acgtcgtgcc
     9121 gggtgaaggt gcaggcggcg tggacgaccg cgtccgcctg cgcgacggcg tcccgcagcc
     9181 cggccgggtc ggagaggtcg ccctcgatga cgtcgacgcc ttcggtggcg atcagatggg
     9241 cggactcggg ccgggccagc gccagcacgg ggcggccccg ggcggcgagt tcacgcacga
     9301 cgaacgctcc cacgccgccg gtcgcgccgg tgaccagtac cgtgcccggg cggatgtccc
     9361 gggagcgggg ggccggcctg ctcgcggcct tcgccgcgct ctgccgtgcc gcccgttctt
     9421 cgaggagcgc ggtcagcgcc cggggcgtac gggcctggag cacgtcgagg cccgtgaggg
     9481 gcagtccgag gtcggtacgc agccgttcgg cgagctgcac ggctttcagg gagtggccgc
     9541 cgagggcgaa gaagtcgtcg tccggcgacg ggaggacacc gagcgcggcg gcgaaggcct
     9601 cctcgaccgc ttcggcccgg gggccggacg ggacgttcgg cgtgggcggc ccgggcagcc
     9661 gggcccggtc gagaggcccg gcggccgtgc gcggcagcgc gtcgagcagt gtgaccgtgg
     9721 cgggtaccgt ctcggacgcg agcgaccggc gcagcaggcc cagcagttcg tggccggacg
     9781 ggccgacgct gtcgtgcagc acggcatagg ccacgggcgg cccttgcgcg ggccggacca
     9841 ccgtggcgtc ggcgacactc gggtgcgcgc gcagggcctg cgcggccggg tggcggtcgc
     9901 cttccgggtc agctccgtcc ccggggccgg agccgtcgtc cgggcccggg aggggcagct
     9961 tgctcagggc gagttccggg tcggccgcga ccgcgtggag gagggccgcg tagtcccgta
    10021 cggctgtctc cgccgcggtg tcgtccagcg cgttcgggtc gtactggacg atcgcccggg
    10081 gctgcgcggc gtctcccggg accaggccgt aggacagggt gaacttcgcg ccgtcggagg
    10141 ggacgtcgac gtactcggtc gaggtgcccg gcagccgcag taccgtcggc tcaccgagga
    10201 cgtcggaggt gacgcggacc agtgccgtgc cgtcggcgcc gcgtgctccg gcgccgaggc
    10261 gttcgaggac caggtcgaag gggatgtggc ggtggtgctg ggcttcgagg agcgcgtcac
    10321 tcacgcgtcg cagcagttgg gcgaaggacg ggtcgcccga gacgtccacc cgtacgggca
    10381 gggtgttgac gcacaggccg acgaggccgc gcatcgcgct gccgctgcgg tgggtgcccg
    10441 ccacgccgat gacgaggtcg tcgtcgccgg tgaggcggtg cagtgcggcg aaggcggcgg
    10501 tgagggacac cgcgaagagc gtggcctgcc gctgtgcgcc cagtgcccgc agggcttcgg
    10561 gcacggcggg ggcgaggggt gcgctgtgcg cggccccggg acgcacggat gcgagaggcg
    10621 ccgccggccg gggcaggcgt ggtggggcgg cgtcggccag caggtcgctc cagcggttca
    10681 gttccgcctc gaaaccgggc aggtcgtcgt gttcgcggcg cgcgtggtcg gcgtactgcg
    10741 gcgctgcggc gagtgtgggc ccgctcgttc cgtcggtggc cgccgtgtag aggacggcga
    10801 gttccgtggc caccgtctcc agtgaggcgc cgtcgacggc gatgtggtgg aacgtcagca
    10861 gcagcgtgtg gtcctgcggg ccgtggcgca ggacgagcgc ccgtacggcg tcgccggccg
    10921 cgaggtcgaa cggccgggcc gtctcgcgac gcagcagctc cggagcttcc gtcgcaccgg
    10981 tttcgacgac gtggacgggg accgtccgcg gcgtcgggag cacttcctgg cagggctcgc
    11041 cctcgtgctc cgtgtagcgg gtgcggagga tggcgtgccg ggccaccagc cgggtgaggg
    11101 cggtggcgaa cgcggccaca tcgaacggac cgcgcacacg ggtggcgaac ggtacgtggt
    11161 aggagtcgcc ggcgccgccg agccgctcca tcagccacat gcggcgctgg gcgcgggaga
    11221 gggggacgcg ccctgtctgc gggacgttgg tatcggactc ggcaggggta ccgggctcgg
    11281 cggtggtgcc ggagcaggcg gtgtcccgcg gtgcgtggcc gtcctgaccg gcgcgggcac
    11341 cggcggtggg cccggccgtt gcacggcggc cggttccggc gcgggcgcgg cgcagcagct
    11401 cctgctggag ctgctgccgg cggtcgccgg ccacggagtc ggcgtcagtg gacatcgctg
    11461 tgctccgggg tctcggggtg gaggtctgcg tgggcggcca ggagggcgcg ttcgaccagc
    11521 gcggcctgcg cggcgacggt cggggcggcg aagaattcgg cgagggacag ttccacgccg
    11581 agttcctcgc gcaggtcgtc ggtgacggcg agggccagca gggaatggcc gccgaggagg
    11641 aggaactcgt cctcggcgca ggtgacttcc acacccaggg actgactcca cacctcggcg
    11701 acggcctgtt ccagcggtgt catccgccct gtcggcccgt gggctggccg gccctcggca
    11761 gcgtgcgcac gtgcgctggg tacgcgtccg gagagcgcgc gccggtcgac cttgccggcc
    11821 ggggtgaggg gaagccgctc cagcacggtg accgtgtcgg gaaccaggtg ggccggcagg
    11881 actgcggtga gccgctcccg cagcgccgcg ccgtgaggta cggggccggg cgcggccacg
    11941 acgaaggcga ccaggctcgc ctccagggtg ccggcgccgt cgaccgtgac ggcggcgtct
    12001 gccacgtccg gctgctcgcg gagggtgtgt tcgacctcgg cgggttcgat gcggaagccg
    12061 cggaccttca cctggtcgtc gttgcggccg tggaactgga ggatgccgtc gggccggagg
    12121 gagacgatgt cgcccgtgcg gtagagccgc aggccggccg aaggatgttc gacgaaccgt
    12181 tcggcagtga gggcgggcag gcccgtgtac ccgtgggcga gcctgctgcc gccgatccac
    12241 agttcgcccc ggtctccgtc ggccaccggg tggccgtcgg cgtccaggac gtgcaccgtg
    12301 gccccggaga tgggcctgcc gatcggtatc ggtccctcgc agtcctgctc ggtgacccgg
    12361 tgggcggtgg cgaaggtggt cgtctcggtg ggcccgtagc cgttgacgag ctccagccag
    12421 gggaaggcgg tgagcacctc acgggcctgt gcggcagcca tcgcctcgcc gcccacgacg
    12481 accgagcgga gctgggcgaa gacgcgcgag cggcgtgcgg cgagctggtg gaagagggcc
    12541 gtggtgaaga aggccaccgt cacgccgtgc cgttcgacgt gccgggccag gtcctccagg
    12601 gagggccgct gctcggtgca gacgacgacc gcggcgccgt tggcgagcgc gccccagact
    12661 tcgaacgtcg aggcgtcgaa ggtcatgggc gagtggaaca ggacgcggtc gcggccggtg
    12721 agggtgacgt agtcgggtgc ggtgaccaac tcggcaatgg cccggtgcgg tacgaggacg
    12781 cccttggggc ggccggtgga accggaggtg aacatgatga atgccgggct gtccgggtcc
    12841 gactcgtcga gcggctgacc gctcgtgagc ggctcctcgg gcagggcgag gacgggtccg
    12901 ggcagtgtgg ccgcatcaag cagcttcgcg tcgccgacgg tgagcgtcac ctccgcgtcg
    12961 gcgatcatcg cctcggtgcg cgggcggggc tgggcgggat cgagcggcac gcacacggct
    13021 ccggccagcc acagcccgag ctgcgccacg accgtgcggg aggatcgcgc cgtcaggagc
    13081 gcgacccggt cgccgcgagc cacctcgtgt gcgcgcaggt gtgccgcgag ggcgtggccg
    13141 gcctggagga gacggcggta cgtgagggtc gtgtcgccgt ccacgacggc gaggccgtcg
    13201 ggggtgagtt cggcgtgccg cgcgacgagt gccggcaggg cggtcgtggg gacggcggac
    13261 tgcggggtgg cgaactgcgg ggtggtgagt gtcatgtcag gctccttccg ggcgcggggt
    13321 ccggcgctga tcgaggaggg cggcgaaggc gcgcaggtcg gtgctgcgca gcagttcggg
    13381 ggcgcgcagg cgtactccgg cctcgcgttc gacggtcgcc agcagccgtg cggcgacgac
    13441 ggaggtgccg ccggcgtcgg tgaagttgtc gccgaggccg atgccggggc ggccgaggag
    13501 ctcgcgcacg gtcgtcagta cgagccgctc ggaggcggtg gcggtggcgg tggcgtcggc
    13561 gaggtcgtcc gtggtggtgg ccctgggcgg caccgggacc tgggcctggg ctgccagggc
    13621 gggccggtcc accttgccgt tggcatcgag cggaaagccg tcgacgatcc gtaccgcgct
    13681 gggtacggcc tgctcgggga gccaggaccg gaccgcggcg agcaggtccc cggtcacggg
    13741 ctcggcgccg tcggcgggcc gaacgtgtgc gacgaggcgg ccgtggcccg cgctgtcgcg
    13801 cagcacggtg acgacggcgg tgcgcacccg ggggtcctgc tcgaaggcgg cctccacctc
    13861 gaccggttcg atccgcaccc cgctgatctt cacctggtcg tcgagacggc cgaggaagtc
    13921 caggctgccg tcggccctca tccgtacccg gtcgccggtg cggtagaggc ggccgatcgc
    13981 gggcagcgcc agttctcggg gaggcggggt gaaccggcgt gcggtgagtt cggggtcgag
    14041 gtagccgagc gccaggcagt gcccgccgac gcgcagctca ccctcctgcc cgcgggcgac
    14101 cgggcgtcct tccccgtccg tgacgacgag ggtgacgccc ggcagcgcgg tgccgatggg
    14161 gggcggggcc tggtcgccgg cctccgggtc ggtgccgcgc atcgtgtggg tggtggtgac
    14221 gacggtggct tcggcggggc cgtaggcgtt gtggacggtg gcggtgacgt cggtgccggg
    14281 gcggcggcgc atgcggtcgc cgccgacgac gaggtggcgc agcttcaggt cctgcggcca
    14341 gggccggtcc aggaggggtt cgacggtcgg ggtggccgcc accgcgtggg tgagggcggt
    14401 gtcacgccac cagtcggtga gcaggtgcga gtcccagcgg gtgtcgtccg gggccgggac
    14461 gagggcggca cccgaggtca gggcggacca cagttccagc agatgggggt cgaaggcaac
    14521 gccgatcagc agggactggc ggtcgcccgg ggcgaggccg gtctcggccc ggtaccagtc
    14581 gagggcgacg gacagcgatg actcggcgac ggccactgcc ttggggcggc cggtggagcc
    14641 ggaggtgagg acggcgtaca gggcgccttc gggcgcacgc cgggtgccgc ggacggagcc
    14701 ggcgaaggcc gccaccgcgg cggcgggggc gttgaccccg tcggtgggca gcagcagcgg
    14761 gaagtgcgct ccgctgcggt gttccccggg cagcaggccg gggtcgccta tgaggcaggc
    14821 gacgtcgagg tcctcggcga cggcctggat gcggcgttcg ccggggcggg ggccgagcgg
    14881 caggtagacg gcaccgaggc gggcgagcgc gacggcggtc accaccaggg cggtggaacg
    14941 gtcgaggcag acaccgacca ggtcaccggg gcggacccgg tctgccaggt cggcggcgac
    15001 gagcgcggcc gccgcgtcga ggtcctggta ggtccagatc tgtgtgccgt cgatgactgc
    15061 gggagcctgc ggggtacgcc gggcccagtc ctcgaagcgg gcgaccacac tggtcggttc
    15121 ggcggcgggg ccctgggcga tgctcagcgc ggagccggtc gcgaggtggg ccgtgcgggg
    15181 cgtggtgggg atgacgggcg cggtcgggga ctgggtcatc acgactccgt ggaaagggtg
    15241 gtggtggcga gggcttcggc ctggtcggcg agcacggggt tacggaagag caccctcagc
    15301 ggcgggcgcg tgcccagccg gggctccagc caggcggcca gctcggcggc cagcagggaa
    15361 tggcccccgc tgtggaagaa gtgggagcgg gcgtcgaacc tgccgtggcc gaggaccttg
    15421 cgccagcctt ccgtgagcag agccgtcatc ggatcgtcgg acgcggcgga cccggcggtg
    15481 gccgcgggcc cgggcccgtg gccggttccg ggctcggagc cggtcgcggc atcggacgtc
    15541 gcggcgtcgt cggggtcgag cgccgcggcc cggcgggaca gggccgtacg gtcgggcttg
    15601 cctccggcaa gggtcggcat ggtgtccagc cgtgcccacc gggcgggcac gagggggccg
    15661 ggcaggcggc ggctcagctc ggcgtgcagt gccttgtcgt cgaaggccgc gccgtcggcc
    15721 ccgtcttcga ggaatccgac gagcctgggc ccgccggggt tctcccggtc cagtacgacg
    15781 gcgcaggacc ggccgcccag cgctgcggac gccgctgcct cgatctcctc cagctcgatg
    15841 cggtgaccgc gcagtttgat ctggttgtcg cgccgcccga ggaagtacag cagaccgtcc
    15901 acaccgcggt agccgaggtc gccggtgagg tagacgcgct gcccgtcgag tgcgtcgagg
    15961 gtgacgaacc gggcggccgt cgcctcctcg ttgcccgcgt agccctgggc gagaccgggc
    16021 ccggcgacgg cgagttcacc gactgcgccg gacggcagcg ggcgccggtg ggcgtccagt
    16081 acgtggatcc gctcgcccgg gagctcggtg cccaggggga tttcggcgcc ctcggcgagg
    16141 gcgtcgcggg agacctcgtg gacggtcgag ctgatggctg cctcggtgac gccgtacacg
    16201 ttgaggacgg tggcgtcggt gtcggtgagg acgccgcgca gtgcctccac ggggaggcgc
    16261 tcaccgccga ggaccagcag cctgggcgcc cagctctcgt cacgcagcgc ggggcgcagg
    16321 tcctcgcggg tggcgaggaa gtagctggtg ggcaggttgg ccacggtgac ccgggcggac
    16381 gccagcagtt cggcgagctc ggcacccgtg ggtacctcgt gctcgggcag gaccaggcac
    16441 gcaccggcgt gcagggccgg cagcacctct tcgagcgcca cgtcgaagga gggctgggcg
    16501 aacatcagga cccggtccga ggtggtgagg ccgaaccggt cggcggtcgc cgtcagatgg
    16561 tgcacgagcg ccgcgtggcc gacggcgacc ggcttcggcg tcccggtgga gccggaggtg
    16621 tggatgacgt acgcggtgcc ggggagttcg gcggtcccgc gcgcgggagg cagtaccggg
    16681 gcgtcgatcc gggcggtcgg cagtgcttcc ggcagggccg gggtgccgtc accggtgagg
    16741 accagcgccg gggcgagccg ctccagcagc aggccgagcc gggccggcgg atcggacggg
    16801 gacagcgggc agtagacggc accggtccgc aggcatgcga gcagggcgac gagcgagtcg
    16861 gtccccctgg gcaggaccac ggccaccggc cggccgggcg tcacgccggc ggtgcgcagt
    16921 cgctcggcga gcgagccgac gcggtcgtcg agttcgccgt aggtgagacg gcgggcgccg
    16981 cacagcaggg ccggctgcga cgggtggtga gcggccacgg gatccagcgg atcgcggtcg
    17041 gccgggaccg gcacgggctc ggcggccggc tcgacgacgg tcggtaccag gtcggccagc
    17101 ggcgtctcgg ggctgtcgag ataggcgcgc agcaggtcca ggaagcggcc ggagagcagc
    17161 cgggcgacgt cttcgccgag caggtccatg tcgtagtccc agaccagcgt catgccgggc
    17221 gagccgtggc gcggggtgac gccgcgccgg tcgtccggga gcaggaccac gtcgaggtcg
    17281 aagcgggtgg tgccggtgtt gaagccctcg aagagggtga tgtcgaggcc gggcacgtcg
    17341 atctcgggca gcggtgcgtc gtgggcgctg aacatgacgg agaagagcgg gttgtcggcg
    17401 ccggaggtgt gcatgccgag cgttcgggtc agctcctgga ccggcacgtc ctggtgcggc
    17461 agggcccgga tgagggtgtc ggtgacctcg tccatggtgt cctgggcggg ggcggcgccg
    17521 tccggggcga gcggcagcgg gatggtgttg acgaacatgc ccacggcgtc ctcgtagccg
    17581 acgggccggt tgccgacggc ggtgccgatg accatgcggg agcggccgct gtgccggcgc
    17641 aggagttcgg cgaagagccc gaggagcgtg gagaaggggg tgagaccgcg tgcacgggcg
    17701 tgcccgcgca ggcgttcggc gagatcggcg ccgatcgtct ggcgcagctg tccgccgtgg
    17761 tggttgcggc gggcgccggg gcgggtcagg cccggtagcg gcaggtcgtg ctgctggtcg
    17821 cgcagttcgg cccgccagaa gtcgagcgat tcgggggcgt acccggcacc ggcccggtcc
    17881 cggacgtggt ccgcgtacga cggggcggcc gggagttcca gggtctcccc gaggacgtgg
    17941 gcgcggtaga cgcggaagat gtcgtcgagc aggatcgcga aggagtgccc gtcgtggatc
    18001 aggtggtgct cgacgtggat cagccggtga tgacgctcgg ccagtcgcac gagcgtccag
    18061 cggatcaggg gtgcctggaa ggtgtcgagg ggtgtctcgg cctcggtgcg caggaggcgg
    18121 gcgaaggccg cctcggggtt cgccgccgta ctgaggtcga ccgtgcgcag cctcggcgca
    18181 cattgtcggg cgacccgctg cgccggtacg gacccggtgg agacgacgag ttcgagccgc
    18241 agaccggggt ggcgggccaa ggtggcgtcg agcccccggc gcagggcctc gctgtcgagg
    18301 gtgccccaca ggtccagtga ggcggtgaag ttgtaggcgc gactgccggg ctgcatctgc
    18361 tcgtgcagcc agacgatctc ctgcgaggag gagaggggaa gcatgggcga tccctgaggt
    18421 tgtcgggtcg gtctccggtg ccggtcacgg tcgtgtccgg tcgtcgggcg ggcggcttcg
    18481 cgggtcgcgc ggcgccgctt tctgcgtggg gggatgccat ggggggtgtt ggggtgcgtg
    18541 ccggcgtggg gtgcgcggcg cgggggatgt gctgcggtgc cgggcggtgc tgtggtgccg
    18601 ggcggtgctg cagcggcggg tggtgctgta gtgccgcccg gcgcggggtc cgcgtgagcg
    18661 ccggtgcgcg gtggccgcgg ggcggtgggg ccgcggtgtc actgcacggg gtgctccgag
    18721 gggctcagtg cccgggtgag cgtgtgggtg agcgcgtcga acgcccggtg cgcggtctcg
    18781 tcggcgagta ccgcccggtc ccacaccatc cgcaggcgga tctccgctcc ctgggtgacg
    18841 gagacggcga agggtccgcg gaccggtctg ccgtcgatgt ggacctcccg tccctcgacg
    18901 ccggcgagta ccaggggcgg gcgacggctg tcgtcgtcca cggtgagcag tccgtcgagc
    18961 cctccggtcc agccggagcc ggctgcccgc gcggcggtca cgaccgcgtc gaacggtacg
    19021 tcggcccggt cgaggtcgtc ccaccacgcg tcggccgtca cctccgtgcc gggtccgtgg
    19081 ccggtgtcgg ccggaaagac gagggtgttg aggaagcagc cgacgaccgg ctccgctccc
    19141 gcgggacggc cgccccacgg gtagccgagc gggaccgcgc ggccggggcc gtacagctcg
    19201 cgggccgcgg agcggcaggc gtcgagcagt tgggggaagg ccacgccgcc gtcgtgcgcg
    19261 ggcagccggg cctgcgcggc gccgctgggc catgcgccgt cgggcacgcg tgccgggcgg
    19321 ggtgccgggg cgtgggtgtg cagcgcgtgc agccggtccg accagtaggc ggccgcttcg
    19381 ggcgtctccg ccctttcctc ggcggcgagt tggcgcagga ccgcgtcccg gtaggcggtg
    19441 agttcggctt ccgtatcccc cggtgttgcg tggggttcgg tggcctcctc gccgtaggcg
    19501 gcgccgagtt cgtcgacgat ccgcgccaac gaacggccgt cgcagacggc gtggtccagg
    19561 acgacggcga ggatgtcctc ctcccgctcc tcgtcgcgca cgaggaagag ccgcacgggg
    19621 ggaccctgcg catcccagga gtccaccgcg cgacggagcg cgtcggcggg cgactccccc
    19681 ggttcgaggg ccggccgggt gacgccgacg tccggatcgg cgacgcgcag gacgggagtg
    19741 ccgcggagga cggcgggtcg cgagcgcagg gcggtgtgcc gtgcagcgag cctggttgcc
    19801 gctgcccgca ggcgtccggg gtcgatggtt ccgtacggga acgcgaagaa catgggcacc
    19861 acgtcggggc gtcccgccgg gtccagcgaa cgcaccagca ggaagcggcg ctgtgccccg
    19921 gtgaccggca gcaggacgtc gggacggtca ccggtgagac gccggtagcg ggccaggtac
    19981 tgactggtga tgctgggcat gtggtcctcc ttgtcgtggc cgcagtcgcg cgcaacggtg
    20041 tggcggcggc aggggtggtg gtgaccctcg cccctgcgga catggcggtg tggtcggtgg
    20101 tggcgggccg tgcccgcgcg ggggcccgta cccggccgcc gtgcggtgtt cgggcgatgg
    20161 ccgggcagtg gccgggtggt ggtcaggccc tgggcgcggg ggccggccgt tcgtcgccgg
    20221 cggcggaggc cgtgtcccgc ggtttcccct ggacgcggtc ggcgccgccg tcgtcctgcg
    20281 caccgggcag gtcccgcatc cggcgcagcg gggagagcac cagcggcagt ggtacggcga
    20341 ggatgccgac ggcgcaccag gcgagtgcgg tacgcgaccc gtaggactgg gcgagggcac
    20401 cgcccaggag cgcgccgagc ggcagggttc cccacatgag gaagcgcagc gtggcgttca
    20461 tccggccgag cagccgtggt gggcacatcc cttggcggaa gctgacctgg gcgacgttgt
    20521 agacgacggc tccgaaggag acgaccgctg atccggcggc gaagaggacc gccccgggga
    20581 gaccgtgccc ggacaggggc cacagcagcg cgaacgggcc ggtcacgagg acggacagga
    20641 gcatgacccg ggcctgcccc agcccggctg cgaggcgccc ggcgcacagc gcgcccagca
    20701 gccctccgac ggccgacgcg gacagcacca gccccagtcc gccggcctcc aggccgacga
    20761 cacggacgag atgcacggtc tgcgtcgcca tgaggacggc cgtactgaag ttggcgaggc
    20821 cggtggtgag ggcgatgacg cggagcagcg gatggccgaa gacgaagcgg acaccctcgc
    20881 cgatctcctt gcgcagggat gccccggcgg gagcgggagc gggtgtttcc tcgggctgct
    20941 cgacgcgcag gaggaagagg gcggagagca cgtagccgat ggcgtcgacg atgaccgcga
    21001 ggtgcgctcc gacgagctgg accagtccgc cgccgatgcc ggggccggtc acctgggcgg
    21061 tggaacgaac ggtctccagg gcgccgttgc cggccacgag ttggtcacgg ggcaggatct
    21121 gcggcaggta gctctgatgg gcgacgtcga agaacacggt cgccactccg gtcacgagcg
    21181 cgacgacgta gagctgcgcc atggtcagga cgtcggcgag cgcggccacg gggatgctcg
    21241 ccatggccac ggcacgcacc aggtccgcgc ggatcatcag gggccgcttg cgcatgcggt
    21301 cggtcagtgc cccggccggc agcccgacga gcaggaaggc ggcggtctcc gcggcggtca
    21361 ggaggcccac ctggaaggcg ggagcgtcga gttcgaggac ggccacgagg ggcagcgcca
    21421 ccagtgtcac ctgggcgccg agctgtccgg tggcagctcc cgcgagtaac agtcggaagt
    21481 cgcgcaagcg cagagggcca ccggcggcgg cgcgggatgt gtcggacatg tgaacgacat
    21541 tcatggatcc atcgctcaag agtcaaagca aacctgtcac tttcggactt gttttgcggc
    21601 ggtgtggaca cagatcggga aatccttcgc actacccggg gtacagccgc gtgaattcct
    21661 gccggttgcg ccccaacgcg ggacaggtgg ggcaagggag gacaggggag caccgggagg
    21721 cgccgggcga cgccccttac ccttagtaac cggttcgatc ctgaccgaaa agactcaccc
    21781 gtgatcatgc ttctgcggaa gcacccgttc cgtccgctat ggacgcagcg gctgcggggt
    21841 acggagattc gcgcggcagg gtccggaagt gccccggcgg ctcctcgtca gcgccgcgtg
    21901 tccggggccg cccggtcggc gccggccgtg gtccggcgcg cgcagtgccg gacgaccgag
    21961 gccaggtccc cctccgaccg caacaggctc cgctggacgc gcgcgccgtt gccgtgctcc
    22021 aggaggccgg cgatcccggc ccgcacgagc tccgcgtcgc cggagtcggc cagggcgtcg
    22081 gcaacgtgcc ggtacagggc gtcgacggcg gcctcgggct cggtctccgc cagcgtctcg
    22141 gggtgcagca aaggaccgtc gagtccggag cggcccgcct gccacgacgc gagccggagc
    22201 agtccggtgc tgacccgggc cggggggtca ccggctcgcc actcccgggc cgcggtatcc
    22261 accagcgcac gcacgagggc ggccagcagg acgggggtcg acgcgtcgag acacacgtcc
    22321 gccaccctga cctccaccgt cggataggag gcggacagcc gggcgtcgaa ccagatcatc
    22381 cccgtgtcgc gcagtacgcc cgactcgacc atggcccgca cctccgcgtg gtagcggtcc
    22441 gcagagccga agacgtccac cggcccggcc gtgggcagcc ggttccagac ccggctgcgg
    22501 tagctgccgt acagggtgtc ctcgccctgc cagaacgggg agttcgcgct catcgcggtc
    22561 agtacgggca gccagggccg gatgcggtcc agtacggcca cgccctcctc gtccgactcg
    22621 accgacacgt ggacgtggca gccgcaggtc agctgctcct gcgcggtcat gccgaactgc
    22681 cgcgacaccc actcgtagcg gtgcccgggg gacatcgagg ggcggacggc cagcggtgag
    22741 gtgccgatgg ccgccacgac cgcaccggcc tcggcggcgt gccgggccgc ctcgccgcgc
    22801 caccggagga tctcctcctg cagctcgccc atctccgtca ccggcttcgt gccgaattcg
    22861 acctgctcct cctggagctc cgcctcgaac gtgtggccgg actccttgcc gtccgccgca
    22921 tcggcggttg cggcgcggtc ggccgcggcg agcacggctc ctgacacggc gagcggctcc
    22981 ccgctgtccg cgtccgccag cagcagctct tcctccacgc ccacgcttcg catgcgatcg
    23041 cccatcactt cgccgtcctg ttcaccgatc ggttgtcacc gtctgcccgg gcccaccgcg
    23101 gatatgcgga aggggacccg ccgcaacggg caccggggat gtacagaaca gcaggtggcg
    23161 gggggctcgg gggcgaggcg cggccgaccg tccgcagcgg gagggcgata ctcagcgggg
    23221 accggggatc cggccgcaga gcacgttgcc cggctccgcc gggtcgtcgc tgatccagaa
    23281 ctgacgccac aggagggcga accgctcacg gctgaggtgg ccgtcgccgt ccgggtcgag
    23341 cagctcgaag acgccgtcca ggtcggccgg gcgaccgttc caggtctcca cgagtcgctg
    23401 gtgctcctcc ggcgagatga cgccgtcgcc gttgctgtcc acggcgtcga agacggtgtc
    23461 ggcggtggcg gtgacatccg cgaccatggt gggcaggcgg tcgacgagga cgagcagttc
    23521 gcccatgtcg accgccccgt cgccgttcgt gtcgccggcc tccagcagcg ccgcccacca
    23581 gcccatcagc agcgcctcca cccgcgcccg cagctccgtg ccgggctcga ctcccggcag
    23641 ccggccccag cggccgacca gcgccgtgaa gtcctcctcg cgcaggtagc cgtcgccgtc
    23701 cgcgtcgaac gcggcgaaca tccccctgag cttgcgctcc tgaaacgtgc cggccatgag
    23761 cggcctccct cgacgccgaa cggaaccgtg aaccgccgcc caccgctgcc cggggggcgg
    23821 cagcgcgtaa ctataggtcg gcgaccgcac cggctcccac gggcacgtat gcacgaaatg
    23881 tcaccccgga ggcggtgggt gggggcgtcg gcgcagcgca gcgcgttcgt cgccggggca
    23941 gggccgacgg cgacgcgcga gacggtcagt cgacgggccg ggaggaatcg tttccggtgg
    24001 gggtcgactg cgacttctcg aacggggagg gcaccgggaa gtaggcctcc aggaaggccg
    24061 tgacgacgtt gtgctgctgc gtcgccgaca atccccctcc ggctccgcct tcgtcgggtt
    24121 cgtccgggtc ctcgtcgtcc gcgaggcaga aggcgtcgtg gccgcgctcg gcggccagat
    24181 ccggcagccg ctcgatctcg ctgcggcgcg cggtgctgac gtacgtgtgc gcgaggtcgc
    24241 cctcgaccgc atgtccctcg gcgagcgcca agtgggcggt gagggtgaca ggagcgatgt
    24301 cgtcggcgct gcggaagacc gagcgggcgg tggcggcgag ccgaccgggc agcagttcct
    24361 cgacgcgggt gaaggcggaa cgggtgaggg ggtagggggt gtgcgccagg atgtggggat
    24421 aggtgcggcc gacggcctcc tcgacggcct gccgggtgac cttctgggaa gaagtgaaca
    24481 cgtcgtcccc ggcccgactg cccgggtcca ccgcccgcca gtcgtggaag accttgggca
    24541 gtccggaagg caggaagtag ttctgcgggc gctggggccg gccgaggaag atgtcgtcgt
    24601 tgaagtagag gaagtgctcg gccaggccgg gaatgtggtg cagtcggctc tcgattgcgt
    24661 gggagttgaa cacggcggga gccgccggtt ccgtggacag ctcgcgatgg tcgatgaccg
    24721 tgatgtcggg atggtcggct gcgagccagg cgggagcctg gtcgtcggtg acgaggaaga
    24781 tgcgccggac ccagggggcg taggcggcga tggagcgcag gcagtagcgg agctcgccgc
    24841 ggtcgcggta gcggttttcc gcgaggtcga tcccggggac cccgccggtc ccgtcggtcc
    24901 catcggtccc atcggtcctg tcggtcctgt cggtcccgga ggagcgaccg gtaccggcct
    24961 ccgcctcggc ggcccggtcc cggcggtggc gccaggcggg gtcggcggcg tccacccagg
    25021 tgatcacggc gtcgatcggg aagtcgatgt cgtcggggaa gcggctcgag aagcagtcga
    25081 cgacggggta ctcccggtcg tcgatgcggc ggctggcaga ggcggccagg gagggcaccc
    25141 accacccgta cggggtctcg cgcagcacgg cgagcgcacc ctcgccggag tcgggaatct
    25201 cccagaactc caggtcgcag ccggtctcgg ggccgtagga cagggtccgg ccggaggtga
    25261 tgatcggctg gtggatgcgt acggcccgca cgcgagcggt gtgcgtcgcg tccttggcac
    25321 cggaaccggc accgctcgcg cccctcgcgt cggcgctctc ggcggactcg accgccgccg
    25381 gaaggtcctc ggcgagtacg tccccggcct caccgtcggc cgtgagcaga cgtgcgtaga
    25441 cggggagccc cgtgagggcg gcggcgcagg ccttcagagc cgcggcccgg tcgccgggcg
    25501 cgatggccac ccggtggacg agctccccgt cggggaccag cccgtagggg acacccgcag
    25561 cctccagggc ctcggccacc gagcgaaggc tggcggtacg ggcatcggcg gggagcaggt
    25621 cgtcccgtac ggtcgccaga cgaccacggt ggtggatcag gcccggcacc gtcgccagca
    25681 gctcctcctc gcgggcggtg agcccgctgg gcgcaggggt cctgccgccg atgcgctccc
    25741 gcccggcagg accgggctgc ggcgggacgc cgcccgctcg acgcagcgtc cgggcgagtc
    25801 tgcgcagccc ggcgggcagg agtaggcggg ggacaccctg catgtacgac ctcggtgtgc
    25861 ggtgccggtg cgcggcagcc gatccgccga gcgtcccggg caggagcggc gcgctcagcg
    25921 gcaacgatgg ataccttgtt caccatcact tttgctgttg ttcgcttttc acgcaagagc
    25981 cgtgagggcc gccgtcccga ctcacagcca attctcagct gcgccgacgg cccgccgtcc
    26041 cggcgctgcc cgatccgcgg cccggtcatc gggccgcgac cgcgtacctc tggtgccgcg
    26101 gcccgtcgga aggggatcat ggccggtgcg cgttggccgt catcgccgca gcgagtgcag
    26161 gaggtacgtg tgtccctagc gtcgagtcgt gcgtccggga gttccgaggt cccgctgctc
    26221 cgcgagacga tcggggacaa cctcgaccgg accgtacggc gtttccccgg ccgggacgcg
    26281 ctcgtggacg tggccgccgg ccgccggtgg acgtacgcgg agctggcagc cgacgtggac
    26341 gccctcgccc tggggctgct ggacctcggg atcgtccggg gcgagcgggt cggcatctgg
    26401 gcacccaacc gcgccgagtg gacgctggtg cagtacgcca ccgcgaagat cggggcgatt
    26461 ctggtcaccg tgaacccggc gtaccgctcc cacgagctgg agtacgtgct cgggcagtcc
    26521 ggcatccgcc tgctggtcgc ggcggagcgc ttcaagagct ccgactacgc ggcgatggtc
    26581 gaggaggtcc ggccgcgctg cccggggctg gagttcaccg tcctgttcga cggaccgcgg
    26641 tgggacgcgc tactggaacg cgggcgcggg gccgatccgg ccgcactggc gcgggcgcag
    26701 gccgcactga gcccggacga ccccatcaac atccagtaca cctcgggcac cacgggcttc
    26761 cccaagggag ccaccctctc gcaccacaac atcctcaaca acggcttctt cgtgggcgag
    26821 ctgtgcgggt acggcgaaca cgaccgggta tgcatcccgg ttcccttcta ccactgcttc
    26881 gggatggtga tgggcaacct cgcctgcacc agccacggtg cggcgatggt gatcccggcg
    26941 cccgccttcg acccggcggc gacgctggcg gcggtggagg cggaggcctg cacctccctg
    27001 tacggcgtcc ccaccatgtt catcgccgag ctggccgccc ccgggttcga cgggtacgac
    27061 ctgtcgagcc tgcgcaccgg gatcatggcg ggttcgccct gcccggtgga ggtcatgacc
    27121 caggtgatcg agcggatggg aatggccgag gtctccatct gttacggcat gacggagacc
    27181 tctcccgtgt ccacgcagac ccgtgtggac gactcggtcg agcgccgggt ctccacggtg
    27241 ggccgggtcg ggccgcacct ggaggtcaag gtggtcgatc cgcagtccgg ccggacggtc
    27301 ccgcgcggca ccccgggaga actgtgcacc cgcggctact cggtgatgct cggctactgg
    27361 ggcgagcccg agaagaccgc agaggcagtc gacccggagg gctggatgca caccggcgac
    27421 ctggcggtca tggacggtga cggctacctg agcatcaccg gccggatcaa ggacatggtg
    27481 atccggggag gcgagaacct ctacccccga gagatcgagg agttcctcca cgcccacccc
    27541 gacgtcatgg acgtccaggt catcggagtg cccgacccga agtacgggga ggaactgatg
    27601 gcgtgggtac ggatgcgcga gggggccgag ccgctgacgg cgcaggccgt gcgcgcgtac
    27661 tgcgcggggc ggctcgccca cttcaagatc ccccgctacg tccacgtcgt ggaggagttc
    27721 ccgatgaccg tcaccgggaa gatccgcaag atcgagatgc gcgcgatggc gacccgcctg
    27781 ctggaggagg gggccgcgtc cggcggcgcc tgaccccgct ggggcgggcc ggggcgggcc
    27841 ggggccgggg cgggccgggg ccgcgacatc gcccgctgcg cagttgcgcg acccaccgcc
    27901 ggtcggggcg gaaggcgcct cgtcacgtac cggcgggccg cgggccgcgt gcggccagcc
    27961 tgcgcgagtg tggcgtgcgt acgcggcgac gccggcgcgg caacatggtg ttcaccacat
    28021 cgcgcacccg gggtaacaac cgcttcctag cgtgacggcg tgggaccgag gcatgaacag
    28081 cggcgccgga gaacactcat gacggcccat cagtccatgc cctgccgtcg gcgcgcccgc
    28141 acgggctccg taccgcatcg cagcacctgc accagccctg cacctggccc cagccccacc
    28201 gggaggcgtg gcatgagcac caccgagtcg cggcatacca cgacagacac cacgaagacc
    28261 gctgccgacc aggcggtcaa ggagacgctg gaggactaca ccctccgttt cgcaccccgt
    28321 agttaccgcc gctggacccc catggtcgtg gccaccacgg ccctcggcgg aatcgcctac
    28381 atggccgact tctccatcgg cgccggcatc ggcctggccc acggcaccgg caacgctctc
    28441 gtggccatca ccgttgccgc ggtcgtcatc ttcatcaccg gcttcccgct ggcctactac
    28501 ggcgcgcgct acaacatcga cctcgacctg atcacccgcg gctccggctt cggctactac
    28561 ggctcggtcc tcaccagcat catcttcgcc agcttcacct tcatcttctt cgccctcgaa
    28621 ggttcgatca tggcccaggg cctcgaactc ggcctcgggc tgccgctctg gctggggtac
    28681 gccgtgtcca ccctcatggt gatcccgctg gtcgtctacg gcatgaaggc gctcagcaag
    28741 ctccaggtgt ggacgacccc catctggctg ctgctcatgg tcggtccgct ggtgtacctg
    28801 atcgccaacg accccggcac cgtggaccgt ttcctcgcct accccggcac gaccggcgac
    28861 ggcgccgtca acaccgcctc cgtcatgctc ggagcgggtg tgtgcctgtc cttgatcgcg
    28921 cagatcggcg agcagatcga ctacctgcgc ttcatgccgc ccaagaccgc ggcgaacaag
    28981 cgcagctggt ggaccgccgt ggtcatggcc ggccccgggt gggtcgtgct cggtgcgctc
    29041 aagcaggcca tcggtgtctt cctcgccgtc cacatcatcg ccgaggtcgg accggcggct
    29101 gcgcccgagc ccatccagca gttccgcagc gccttcgacg cgatgatgcc gggctggttg
    29161 gtcgtcccgc tggccgtggt cctggtggtc atcagccaga tcaagatcaa cgtgacgaac
    29221 gcgtactccg gttccctggc ctggacgaac tccttcaccc gcgtcaccgg gcactacccc
    29281 ggccgcatga tcttcgtcct ggtcaacctg gccttcgcac tggccctgat ggaagccgac
    29341 atgttcagct tcctgggcag catcctgggc ttctactcga actgcgcgat cgcctgggtg
    29401 gtcaccgtgg ccaccgacat cggcatcaac aagtacgtgc tgaagctgtc cccgctccag
    29461 ccggagttcc gccgggggat gctccacgcc gtcaatccgg tcggtgtcgt ggctttcgtc
    29521 gccgcctccg gcctgtcgat cgccatgtac ttccacgccc tcggcgacac cctccagccg
    29581 tactcgcccg tggccgcagc cgtcatcgcc ttcgccgtca caccgctgat ggccgtcgtc
    29641 accaagggcc gctactacgt gcgccgcgcc gacgacggca tcggcgagcc cctgctggac
    29701 accgacggga acccgagcgg agtcaccctc gactgccacg tctgccggca gtcctacgag
    29761 cgccccgacg tcaccgcctg tgtcacccac ggcgcggtcg tctgctcgct gtgcctgagc
    29821 accgacaggg gcggcgacca cgtcctgccg gccgcggagc cgcgggcggc cgaccgtcac
    29881 tgaacgggcc ccggtccgga gcgtgtccgt gtccctcacc ggcacgctcc gggccggggg
    29941 ccgccccggc gatcgaccgt gtaccggccg cgggggcgaa gccccgtcag ccgctccagg
    30001 cccttcgcac cctgccgtcc tcgacctcga ggttcagcct gccttcgacg tattccatgg
    30061 tcagcatcgt gccgggcgcg accgtacgca ccgtcgtcca gccgtgcgcc agcgcccggc
    30121 gtttcgcctc gccggtgtcg agccctgtgt agtgcgccgg atcgtcggcg ccgggtgagg
    30181 aagcggaagc agtcatggcc ctcacctgcc cgaccgaggt gctgaacatg ccctgccggc
    30241 cggcgcggcg actccgcagg tccgaggacg ccccgctccc gtcgtcactc cccggccaac
    30301 aggagccgct tctgcggttt gcccatggca ttgcgtggaa ccgcagcaat gaagcgaacc
    30361 tcacgcggcc gcttgtgcac cgacagatgc gtggcaacga agtcggtcaa ctcggcgccg
    30421 ctgaccccgt cggcgacgac gaacgcgacg atccgctccc ccaggtcggc atccggcaca
    30481 ccgatcaccg ccgcctcctg cacccgcgga tggtccagca gcgcgttctc gatctcaccc
    30541 gccccgatcc ggtacccccc cgacttgatc atgtccgtgg acgcacgacc cacgatccgg
    30601 tgcacgccgt ccccgtcaac ggcggcaatg tcacccgtgc ggaaccaccc gtcctccgtg
    30661 aaggcggcag ccgtcgcctc cggtcgcccc aagtaccccg agaacaacgt cggccccacc
    30721 agctggagct caccgatctc ggcacccggc tcggcggcga tacgcgtacg gattcccgtg
    30781 agcggcgtgc cgaccgcgcc ggggcggacc tcaccacctg cccgcccgct cagggtgatc
    30841 agggtctccg tcatcccgta ccgctccacc ggccggtgcc cggtcaaccg ctccagatcg
    30901 cggaagaccg gcgtgggcag ggccgcgctt cccgacacca gcaaccgggc cctcgacaac
    30961 gcggccgccg cctgcggagc agcggcgatg cgcgaccaca ccgtcggcac cccgaaatac
    31021 aggctcccgc cggccgccgc agcctcggcg tacgcctccg gcgtcggtcg gcccgtgtgc
    31081 accaggcggc tccccgtccg caaggccccc agaacgccca ggaccagccc gtggacatgg
    31141 aacagcggca acccgtgcac gagcgtgtcc tgcgcactcc actcccaggc tgcggcgagc
    31201 gcatccaggt cggcggtgat cgcggcggcg ctgaggacca ctcccttggg ggcgcccgtg
    31261 gtcccggagg tgtagaggat cagcgcggga tcctcgggtc ccgccgcctg cgcggtgggt
    31321 gcggccgatg cggcaggcgc gcggcgggcg aagtccacct cgatgaggcg ggcgccggag
    31381 tcacgcagga tgtgatcacg ttcggcgggc ccggcatcgg ggggcagcgg cacgcacggc
    31441 accccggcaa gcagtccccc gaccaccgcg gcgacggtct cgagcgaggc ggtggcggtc
    31501 accgcgaacg cccgcaccgg gccgagggcg gcaaggtctg cggccacggc ccccgccgca
    31561 cccagcagtt cctcgtagga ggcggtacga cccgcgacgc tcacagcatc cgcgcgatcc
    31621 ccgaaaacac ccgtcagggc ggtcagcatg acggcaactc cgatcagcaa tgagcagaag
    31681 caacccggcc agcctacggc gaccgcacga gttctccgcc tccacggacc tgtcaccgag
    31741 cccgaagtcc gggacgcgcc aagaggaatg gtccgccacc acggggtact cgcagtacat
    31801 gaacacacac atcgacgacg ggacgccgca ctccggacgg gtacctgccc tggacaagac
    31861 ctcggagcgc tggctcggcg ccgtggccac cgtcgaggag tcgacggcgc tggacccggc
    31921 catccgggcc ctccagcggg gcatccgcgg ccttccgctg ggtgcacttc gtgggctgct
    31981 gcgcggtgag ccgctggggc accccgcaca ccccatgctg gtgcaggtac cgatggggtg
    32041 ctggctgtcg gccgccgtgc tggacaccgt gcccggagca caccggtacg ccacggtcct
    32101 gaccgcggtc ggccttgccg gcgtcgctcc ggcggccgca gccggatggg cggactgggc
    32161 ggagctgccg cctcgacagg cccgcgtggg tgtcgcccat gcgctggcca acgctgccgc
    32221 cgtcggctgc tacgcggtcg cactgtccga ccggctgcgg ggtcggggcg cgcgcggccg
    32281 cttgtggtcg ctggcgggac tgggcgcggc ggcggtcagc ggggctctgg ggggacacat
    32341 cgcgtacggc gaccggatgg agcgcggcgg aacgggcaac gacataccac ccggcatcgc
    32401 ctgatttctg tgatttgctc cggattcgcg gattcgcggg tttccggcgc cgggctcagg
    32461 gcacgcgccg actgggggat gccgacgtac agggaggatc cgccatggaa gaccagggag
    32521 gcgccggagg cgccccgctc cacgaccacg acgacgagca gagccgacgc aggacacccc
    32581 acgtcgcgcc tcgctccgct gcgccgggca aggacgtacc ccccgtgcgg agggcggaca
    32641 cggacgaggc cagccgcctg gaccggccgg gcgatgacgg cgagtccccg cgcgaacggc
    32701 gccggcccgg acgcgagcac tgacgtcgag tgccgacagc gagcagtact gagggcgagc
    32761 agtgctgaca gcgagctctc gcggccgcag cgtgatccgg cgatcgggac ctgctcaggg
    32821 cccgtagcgc atgcgtccca aggccgtcat cggccggtcg tgcgcggcga ccggcgccgg
    32881 gaggcaggtg gagccggtca ggtagcggtc caccgcggcg gccgccgcgc ggccctcggc
    32941 gatggcccac accaccaggg actgccccct gcccgcgtcg cccgcgacga acacgcccgg
    33001 cgcccgaccg gcgtccgccg cgaacccggc gtcccgcgcg aagttgccgc gttcgtccag
    33061 ggccagtccc agctgctcgc gcaggccgcc ggcccgctcg gggcccgaga agccgagggc
    33121 cagcaggacc aggccgaccg gtatgacctg ctcggtgccg gccagcgggc tgcgggccac
    33181 cggctcgacg gcggtcaggt gcagcgcccg taccctgcct tcctcgtccc cctcgaagcg
    33241 cagggtggcg caggcgaaca gccgggggtc ccggtccgcg cgcccgcggg cctcctcgtg
    33301 ggcgtgggag atgcggtagg tccgcgggta caccggccac ggctcgtcgt cggtccggcc
    33361 cgttccgggc tcggggttga tgtcgagctg gagcacggag gtcgcgccct gccgcaaggc
    33421 cgtcccgagg cagtcggagc cggtgtcccc gccgcccacg atgaccacgc gcctgccctc
    33481 ggccgtgagg ggggataccg gatagtcacc ctcgcgtacc cggttggcgc aggtcaggta
    33541 gtccatggcc tggtggatgc cctgcaggga acggccgggg accggcagct cccggcgctc
    33601 gccggcaccg atcgcgacga cgacggcgtc gcacccgctc cgcaactcgt ccgctccggc
    33661 accggccgca ccgccgacgt cggcccccgt ggcgaacacc gtgccctcgg cccgcatctg
    33721 ctcgatacgg cggtccaggt gcaccttctc catcttgaac tcggggatcc cgtagcgcag
    33781 cagtccgccg atccggtcgg cccgctcgtg gacggtgacg cggtggccgg cgcgggtcag
    33841 ctgctgggcc gcggccagtc cggccgggcc ggagcctatg acggccaccg tcttgccgct
    33901 gtgcctctcc gggggcctgg gcatcatgaa gccgcgcctc aggccctcgt ccgcgatggt
    33961 ctgctcgacg ttcttgatgg tcaccgggtc ggcgttgatc gcgaggacac aggcgtcctc
    34021 gcagggggcc gggcagagcc tgcccgtaac ctccgggaag ttgttggtcg cgtggagccg
    34081 ctcgtacgcg gcacgccagt cgccgtgggc ggcgtacgcg ttccactcgg ggacgaggtt
    34141 tcccagcgga cagccggtgt ggcagaacgg gatgccgcag tccatgcagc ggtcggcctg
    34201 ccgggagacg agcggcagca acgcccggcc cgcgtggacc tcgcgccagt cgccgagtct
    34261 ctcctcgacc gggcgggcgg gcacggcctc gcgggggatc ctgaggaagc cgaacggatc
    34321 ggtcacgcgc cgcctccctg gatcgtgcgc ggcggggtac acggcgcgcg ccgtgccttc
    34381 ggtacacgcg ttctatggcg gttcggccag attacgccgc ctccggggcc ctgcccaagg
    34441 ccaagcgagg tgggtgaccg gacgggcacg caaggtggtc gccggccggc ggtcatgggc
    34501 ctccgtgagg cggcagcgct gctgcccggc ttcgaccggg cctcccccgt cgggacgacg
    34561 acgatcgatc cgctccacgg ctgaatccac ggcggacgcg gccggggcgt cgggcgtggc
    34621 gtcgggatct gtgcgggccg tcgggtgatg atggcgccgt gcgacttgat cacgtgtcct
    34681 atgcggtggc ccgcgacagc ttcgtctcga ccgtccagtg gatcggatcg gccctcggcg
    34741 ccgggttcgt cgacgggggc gtgcacccgc gattcggcac ccgcaatttc atcctcccgc
    34801 tgagcggcgg cacctacgtc gaggtcgtca ccacactcga ccaccccgcc gccgaccgcg
    34861 cacccttcgg ccaggcggtc gcgcgccgcg ccgccgaggg cggcggctgg ctcggctggg
    34921 tggtctccgt cgacgacatc gccccggtcg aggcccgcct cggccgcacc tcggccgagg
    34981 gccaccgtgt ccgccccgac gggttcgacc tgaggtggaa gcagatcggc ctgctggaac
    35041 tgctggaagc cccacaactt ccctacttcc tccagtggtt ggtccccacc gaggagcgcc
    35101 cgagcgccga cccgcgcacc tccaccacca tccacggggt ctccatcgcc ggcgacgccg
    35161 cctccatcgc cgaattcctc ggcgaaccgg ccgaccaccc cctcgaccag atcgacgtca
    35221 cctgggccga ggacgaggaa ccgggcctgg tctcggtcga gttcgccacc gcccacggcc
    35281 cggtcacgat ctgacccggg cccgactgcc ccacgggagc agccggccgg tgcggcgacg
    35341 caccctcctt cgaagcggtc atggcccgca tccgcgtgcc acgaagcggg cccggcaggc
    35401 cccgaacccg gccgttggcc gtgctcgcgg accgggccca ctcccccgtg ccatccggtc
    35461 ccacctgcga cgagcgtcga acgctgcatc aaccgcctcg agcagtggcg cggccgcgcc
    35521 acacgatgcg acaaactcgc catcgcccac caggcagcac tccacctcgc cgccatcctc
    35581 atccgggcac gacgctgacc gaaaagacag aacctagttg aacggttcga gcgtcatgaa
    35641 ggcctcctgc gggtttccgt cgtggaccag cgactcgtgg gcgcccacgt cgtcgaaggc
    35701 gaagccgtac gccttgccgt cggccatctg tccgtggatg atccgggagt agtggttggt
    35761 cacggcgtca cggtagaagt tggcgttgtt cggatcgggt tggccgggat tggtcagaag
    35821 cgtcgaccgg ttgaagcccg cgcacagggt gcgggagatc gggccgcgga cctggtcgtt
    35881 gggggcgtcc aggagcttgt agcagccgaa gacgctgtcg gagtccggct tctggaagct
    35941 ggtgacgacc gctcccgagc cgttggtgaa gttcatgacg ttgcccgaga cccggccgta
    36001 gtacttggtg ttcggctggt tcgcgaacgg cgtcacggtg agggtggagg agccgtactt
    36061 gttccagacc cggttgatgt agtcgttcat gacgccggcc ggtatgccgc ccgcctcgat
    36121 gccgtgcccg ggcgagagcg cgcgcagcgg cgtgccgtcg ggccggttct ggatcaatcc
    36181 gccccagccg gccgaacgca gctggctgaa gacggcgttg tagccgcccg gcttcagccg
    36241 gcccgtggtg ctgaccgcgc cgttggccgc tttgacgccc accgcgtacg gagcggagaa
    36301 catgtcgacc tgggtgctgt tgatccagag gccggcgtcg ttgagggtgt actcggacca
    36361 gttgaacagg atgttgcggt tcgggtcggc ggggttctgc acggcgggct gcaccaggcc
    36421 gccggtggtg agcttgaaga cgatcttctg gccgatggag aagtagatcc gcccggagaa
    36481 cttgggcatc cggatcgtct tggtctgccc gttggccgga cccgtgatcg atgcgtcggg
    36541 tgcgggcgtg gggggattgc ctcccacggg ccaggggtgg aacgtgccgt tggcgtcggc
    36601 ccagccctgc tggccggtgg tcagcagggt gcccaggttg tagacgtaca ccggctcgct
    36661 gcggcccgag ctgttcttga tcgtgagggg aatggtcgcc ggtacggcct ctgcggacgg
    36721 cgacgggccg aagaccatca gcccggcggc gacggccatc gccgagaccc cggacaggaa
    36781 taccttcgat aagcggaaca cgttcttcct ccttgtgggg ggcacctgaa ggtgggggca
    36841 ggtgcggcat ctcccagcac cacgcattga cacattgatg cttgagagcg ctctcagcct
    36901 cgggctgcgt tcaatttatg tcaatggacc cgacacagct cgacggcccc gatcggcctc
    36961 gcggccgggc acgttttcgc tgcccgccga ggggagataa ggatcccaac cgtgcagctg
    37021 cgccaaccgg gggcgtcatg aggtacgacc tgtcccaccg cctggtcgtc gggatcgcct
    37081 ccagcgccct gttcgatctc accgactgcg acacggtgtt ccgggaggaa ggggaggacg
    37141 tctaccggac ctaccaggcc actcatgcgg acaacgtcct gggcaaaggg gtcgccttcc
    37201 ccttcgtcag acgcctgctg tcgctgaacg acctctcgga acagtccgat ccgctggtcg
    37261 aggtcatcat cctctcgcgc aacgacccgg acaccggatt gcgcgtcatg cgttctatca
    37321 aggcctacga cctgccgatc agtcgggccg tctttcggca agggcgtcct tcccaccgct
    37381 tcatgcccgc gctgaacatg tcgctgttcc tgtcggccaa cggccccgat gtccgtgacg
    37441 cggtcgcgga cggactgccg gcgggccacg tactgagaac cgcacgcatc gacgacgaga
    37501 ccgaccctga actccgcatg gccttcgact tcgacggagt ggtggcgagc gacaccgccg
    37561 agcggatcta ccagagcggc ggaatcgacg agttccgcgc ctacgaggtc cgcaacgccg
    37621 ccgcgcccca cgatccgggg ccgctacggg acttcctcgc cggcatcaac cgggtccagc
    37681 gcctcgagga agacaggcgc cgcacggatc cgacgtaccg cccacgcctt cgcgtatccc
    37741 tggtcaccgc tcgggacgcc ccggcacatg agcgcgccct tctgagcctc aaggagtggg
    37801 gcctacgggt caacgacgcc ttcttcctcg gcggcatcga gaaggccgcg gtcatgaagg
    37861 cgctcgaccc gcacatcttc ttcgacgacc aggtcgccca cctgaacggc acggcgcagg
    37921 gcactcccag cgttcacatt ccgttcggag tggtcaacgc gaccccaccc gcgagtcggc
    37981 gcggatcccc cgatcaaggg cacaccacct gacggggtca agattcacat gggtgatcca
    38041 gaatgccagg agtgttcggc gggtacgcga ggtcggtcac ctgtttgcca cgtggaggtc
    38101 accttgccgt ccgctctctc cgacacgatc tcgacccacc tggccgttgc cggcagcctc
    38161 ctgccggtgc agacccgggc cgtctacgac acatccgacc cctacgcggt ccggttcgac
    38221 ttcatcctcg acggctgccc tcccattcgg tggcacttcg agcgggacat gctggccgag
    38281 ggggtgcgcc gcccggtggg ggaaggcgat gtcagcctgc gcccacggtg ggcgggcgga
    38341 cgtgaaaccc tggtgatgca gctgtggggg gacacccggg tcggctacga gtccgcggtg
    38401 ctga
//
