LOCUS       NZ_BMVE01000016        10891 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces goshikiensis strain JCM 4640 sequence16, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVE01000016
VERSION     NZ_BMVE01000016.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 159011)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650555.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:30:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,491
            CDSs (total)                      :: 7,410
            Genes (coding)                    :: 7,286
            CDSs (with protein)               :: 7,286
            Genes (RNA)                       :: 81
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 44 of 125
            Pseudo Genes (incomplete)         :: 101 of 125
            Pseudo Genes (internal stop)      :: 9 of 125
            Pseudo Genes (multiple problems)  :: 27 of 125
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 52692
            Orig. end                         :: 63583
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVE01000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="2"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..10891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10891
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5891](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5891
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    877..888
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.96"
                     /tool="antismash"
     misc_feature    882..895
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.69"
                     /tool="antismash"
     gene            1101..1568
                     /locus_tag="IE248_RS32255"
                     /old_locus_tag="GCM10010336_65740"
     CDS             1101..1568
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146490.1"
                     /locus_tag="IE248_RS32255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65740"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_047961254.1"
                     /transl_table=11
                     /translation="MNDRAPAGNAIPLDRLARQATRLAQLVNAATRAASASAGLTHADT
                     DVLLALYGAPEHRLRPTALSTACNLSSGGTSNVILRLMQAGYVNREADAYDGRSTWVQL
                     TMEGEALASSVLESATAAHARLLDRLPGGIAVALDELLEIALGHLDDGAGR"
     gene            complement(1452..2255)
                     /locus_tag="IE248_RS32260"
                     /old_locus_tag="GCM10010336_65750"
     CDS             complement(1452..2255)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013488.5"
                     /locus_tag="IE248_RS32260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65750"
                     /product="DsbA family protein"
                     /protein_id="WP_073776682.1"
                     /transl_table=11
                     /translation="MAVGIDSWFDYGCPSSMITRHFLTEELAGSGVQVRWHPHESRRGA
                     WDPVWSAQRWDRGLRPLADRLGVRVSPVAPANTSSRLALQGYQYAADHGRGDAYSDQVF
                     SARFTEGQDIADLAVLAEAARRAGLDPERFRAAVRSPYYVRRHQEAVTPRRSVRIAPTV
                     VADGYRVEGVPTGAQMAKLIALSRSSPRASTAAAPAAAASPPGVKALRRAPGERTAAGR
                     QKARRARLAACAVVEVAEGDLQEFVERDGDAAGQPVEEPGVRRCG"
     misc_feature    3060..3074
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.04"
                     /tool="antismash"
     gene            3092..3727
                     /locus_tag="IE248_RS32265"
                     /old_locus_tag="GCM10010336_65760"
     CDS             3092..3727
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740923.1"
                     /locus_tag="IE248_RS32265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65760"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_008740923.1"
                     /transl_table=11
                     /translation="MTKQERAVRTRHALLRSAAAAFDQRGYAAATLSLISNGAGVSPGA
                     LHFHFENKAAIAAAVELEAADTLCMVATHVYMRQGSALQALADTSHALARAFTTDVVVR
                     AGFQLGREAAYVSSLDLHKDWERYVHRLLARAAEQNTLQPGLSHRQMAAMVVAATVGFE
                     VLGQGEREWVSAHSLTSFWRLILPSLATPEALCELDPTGGRLGVMSRS"
     gene            complement(3948..4769)
                     /locus_tag="IE248_RS32270"
                     /old_locus_tag="GCM10010336_65770"
     CDS             complement(3948..4769)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010032559.1"
                     /locus_tag="IE248_RS32270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65770"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_308438201.1"
                     /transl_table=11
                     /translation="MHSDPRSTRSTRSTRTLGGNVARQERAVRTRRAILEAAAAVFDER
                     GYEAATIADILARAGVTKGALYFHFCSKQELAQGVLDEQFVEGGVPPRESKLQELFDVA
                     MVLAHRMRRQPLLSAGARLSLEPEMREIFGGGSVPGWIGVVEELLAQAKAQGELLPHVN
                     PAETAWIMSASWTGVQVYSQTLSAREDMERWVSALYQHLYPGIATPAVLARLDMAADRG
                     DRVVEEIKLLEARAQEDCEDEAEIGAEAGAETGAGAVAGAGEEPARDAAAV"
     misc_feature    4792..4808
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.73"
                     /tool="antismash"
     misc_feature    4795..4808
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.23"
                     /tool="antismash"
     misc_feature    4796..4809
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.1"
                     /tool="antismash"
     misc_feature    complement(4797..4810)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.98"
                     /tool="antismash"
     misc_feature    4836..4849
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.93"
                     /tool="antismash"
     misc_feature    4837..4850
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.51"
                     /tool="antismash"
     misc_feature    complement(4840..4855)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.33"
                     /tool="antismash"
     misc_feature    4890..4905
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.23"
                     /tool="antismash"
     gene            5001..5891
                     /locus_tag="IE248_RS32275"
                     /old_locus_tag="GCM10010336_65780"
     CDS             5001..5891
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569591.1"
                     /locus_tag="IE248_RS32275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65780"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_073795008.1"
                     /sec_met_domain="AfsA (E-value: 5.4e-22, bitscore: 71.0,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTVPREYVHRSSVAEVFLTGYKRIDDNVFLIGGQWPRAHTFFT
                     GVDGRSHDPVQAAETLRQAGLLLCHSEYGVPLKHKMLLWTLDFTADPSQLRIGTSPTEL
                     EILATCRDFVWKGSKFSGVLEVTIRCDGRDAASGTATFSCVSSAVYRRLRGEAGFESAL
                     RPLPRQTPVPTAEAGRLLAADVVLAPADRPGRWLLSPDLGHPILFEHANDHHPGMVLVE
                     AARQAAYATLAGAAFTPTGIETAFRSYAEFDAPCWIDTELVPTDDPAVRRVRVTGHQDG
                     RTVFESTVTGAVPVL"
     gene            5955..6746
                     /locus_tag="IE248_RS32280"
                     /old_locus_tag="GCM10010336_65790"
     CDS             5955..6746
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (18-180). E-value: 3.1e-12.
                     Score: 38.7. Matches aSDomain:
                     nrpspksdomains_IE248_RS32280_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489554.1"
                     /locus_tag="IE248_RS32280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65790"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_229895687.1"
                     /sec_met_domain="adh_short (E-value: 6.3e-37, bitscore:
                     120.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRASLPVAGNSSGVLAGKSALITGASSGIGAAAARVFCREGARVT
                     LVARREPELAALTAELTAAGHQAQYVLADVTRAGDAVRAVAAAVEAYDRLDVAFNNAGL
                     GALPGPMHLQDDKVYDEVMDVNVRGVWNCMRAELTAMLESGGGAIVNNSSTAGLVATAA
                     GSPYIASKHAVIGLTKAAAKEYAQHRIRVNALATGATRSEMITGWMAEDPAREPAMAQK
                     AMLRRLAETEEIAEAAVWLCADRSSYVTGTTLAVDGGRLSH"
     aSDomain        6009..6494
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS32280_PKS_KR.1"
                     /evalue="3.10E-12"
                     /label="IE248_RS32280_PKS_KR.1"
                     /locus_tag="IE248_RS32280"
                     /protein_end="180"
                     /protein_start="18"
                     /score="38.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="SALITGASSGIGAAAARVFCREGARVTLVARREPELAALTAELTA
                     AGHQAQYVLADVTRAGDAVRAVAAAVEAYDRLDVAFNNAGLGALPGPMHLQDDKVYDEV
                     MDVNVRGVWNCMRAELTAMLESGGGAIVNNSSTAGLVATAAGSPYIASKHAVIGLTKA"
     CDS_motif       6015..6101
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS32280_0001"
                     /evalue="1.40E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE248_RS32280"
                     /protein_end="49"
                     /protein_start="20"
                     /score="11.3"
                     /tool="antismash"
                     /translation="LITGASSGIGAAAARVFCREGARVTLVAR"
     gene            complement(6781..8160)
                     /locus_tag="IE248_RS32285"
                     /old_locus_tag="GCM10010336_65800"
     CDS             complement(6781..8160)
                     /NRPS_PKS="Domain: AMP-binding (14-362). E-value: 5.7e-69.
                     Score: 224.6. Matches aSDomain:
                     nrpspksdomains_IE248_RS32285_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740919.1"
                     /locus_tag="IE248_RS32285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65800"
                     /product="AMP-binding protein"
                     /protein_id="WP_190032536.1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-76, bitscore:
                     250.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTALDGVYGDRKDALSVAGRTASYEELLGAARAVAADVAGAPAF
                     AVTATASLETVAAAVGGLLAGVPFVPLPPDAGPAEREHILRDSGAVLTDVDFDRRSSGS
                     AGPGAGAAAAPGAAPEDPALVLYTSGTTGAPKGVVLTGAAIAADLDALAEAWQWSAEDT
                     LVHGLPLFHVHGLVLGVLGALRSGSRLVHTGRPTPQAYAEAGGSLYFGVPTVWSRIAAD
                     APAAEALGGARLLVSGSAALPAPVFRDLERLTGLRPVERYGMTETLITVSGRAGGEVRP
                     GTVGTPLPGIRTRIAAETGAEIGELQLTGPTLFSGYLGRPEATAAAYTQDGWFRTGDIA
                     AVDPADGVHRIVGRASIDMIKSGGYRIGAGEIENALLDHPRVSEAAVVGVPDADLGQRI
                     VAFVVAEGVTGAELTEFVAAHLSVHKRPREVRFVAAVPRNAMGKPQKKLLLTGEFGPQA
                     G"
     aSDomain        complement(7075..8118)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS32285_AMP-binding.1"
                     /evalue="5.70E-69"
                     /label="IE248_RS32285_AMP-binding.1"
                     /locus_tag="IE248_RS32285"
                     /protein_end="362"
                     /protein_start="14"
                     /score="224.6"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="ALSVAGRTASYEELLGAARAVAADVAGAPAFAVTATASLETVAAA
                     VGGLLAGVPFVPLPPDAGPAEREHILRDSGAVLTDVDFDRRSSGSAGPGAGAAAAPGAA
                     PEDPALVLYTSGTTGAPKGVVLTGAAIAADLDALAEAWQWSAEDTLVHGLPLFHVHGLV
                     LGVLGALRSGSRLVHTGRPTPQAYAEAGGSLYFGVPTVWSRIAADAPAAEALGGARLLV
                     SGSAALPAPVFRDLERLTGLRPVERYGMTETLITVSGRAGGEVRPGTVGTPLPGIRTRI
                     AAETGAEIGELQLTGPTLFSGYLGRPEATAAAYTQDGWFRTGDIAAVDPADGVHRIVGR
                     ASIDMIKS"
     CDS_motif       complement(7180..7254)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS32285_0002"
                     /evalue="3.40E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="IE248_RS32285"
                     /protein_end="327"
                     /protein_start="302"
                     /score="29.0"
                     /tool="antismash"
                     /translation="IGELQLTGPTLFSGYLGRPEATAAA"
     CDS_motif       complement(7738..7794)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS32285_0001"
                     /evalue="8.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="IE248_RS32285"
                     /protein_end="141"
                     /protein_start="122"
                     /score="24.6"
                     /tool="antismash"
                     /translation="ALVLYTSGTTGAPKGVVLT"
     misc_feature    8248..8262
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     gene            complement(8330..9685)
                     /gene="gdhA"
                     /locus_tag="IE248_RS32290"
                     /old_locus_tag="GCM10010336_65810"
     CDS             complement(8330..9685)
                     /EC_number="1.4.1.4"
                     /GO_function="GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gdhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740918.1"
                     /locus_tag="IE248_RS32290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65810"
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="WP_100582248.1"
                     /transl_table=11
                     /translation="MKDQKDRLEALRADIERRNPAQPEFHQAVREVLETLAPVFAARPE
                     YADPAVALVERLTEPERQILFRVPWQDDRGRVHVNRGYRVEFNSALGPYKGGLRFHPSV
                     DIGVVKFLGFEQIFKNALTGLGIGGGKGGSDFDPHGKSDAEVMRFCQSFMTELHRHIGE
                     HTDVPAGDIGVGGREIGYLFGQYRRITNRWEAGVLTGKGQGWGGSAIRPQATGYGSVLF
                     AAEMLAVRGEALDGLSAVVSGSGNVALYTIEKLQRLGANPLTCSDSEGYVVDDKGIDLA
                     LLKQIKEVERGRVSEYAARRGSSARFVSGGRVWDVPADVAFPSATQNELEARDARALVA
                     GGVKAVSEGANMPTTPEAVRILQEAGVAFGPGKAANAGGVAVSALEMAQNAGRVAWSEQ
                     RVEDELAGIMRSIHTVAHETAERYGAPGDYVVGANIAGFERVADAMLAQGVI"
     gene            9990..10493
                     /locus_tag="IE248_RS32295"
                     /old_locus_tag="GCM10010336_65820"
     CDS             9990..10493
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268970.1"
                     /locus_tag="IE248_RS32295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_65820"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190032537.1"
                     /transl_table=11
                     /translation="MSTSPLRLEPVTVANFDTVCAIQVRPDQAHLVSPVVKSLAEAYVN
                     GDCAWPRAIVDGDEVVGFVMAFIDIAWNPAADPGDIRSGIWRLNISADRQGKGYGRFAV
                     EAVTAELRRRGADRAYVTWEPGPGTPKPFYLGLGFRSTGERSGGQSVAVLPLAAGQYDA
                     VDAR"
ORIGIN
        1 gcaccgcggt cgcgcaggcg gggtcgaggc ggccgccgct gccggcgcgg gtgctgaagg
       61 cgatccgcag gcggcgtccg gggccttcgg caacggcccg cgcaaacgtt cctgcggcca
      121 ccggcggcgc ccagtacggg tcgcccggcg cggggccgga gatcgcgtcg agcacggcgg
      181 cgctgtcgcg gaccgagcgg ctgacgacgt gctcggccgc gaggccgttc atcaggtcgc
      241 cgacggcggg gcccagcggt gtccgcgccc gggtgggctt gagcccgaac accccgcagt
      301 tggaggccgg gatgcggatg gagccgcccg cgtcgttggc gtgcgcgacg gggaccaggc
      361 cggccgcgac ggccgcggcg gagccgccgc tggagccgcc cgcgctgcgg gcgtggtccc
      421 aggggttcac ggtggcgccc tgggccgtgt tctcggtggt gggcagcacc ccgaactccg
      481 cggtacgcgc cttgcccagc acccgcagcc cggcggcctc gaagcggtcg gtcagctcac
      541 tgccctgcgc cggcacgaac cccttcagga acctcgatcc catcgtcgcc tccataccgg
      601 cgacggtcgg gcctaagtcc ttgagcagga agggcacgcc gtgcaggggc ccccgctcct
      661 cggggtgcgg gccatcgggc tcgtccgcct gggccagcgc ccggtcgaag gaggtgacgg
      721 cgacggaccc cagtgacccg tcgagccttt cgatgcgctc gatggcggcg cgcagcagat
      781 cgccgcgcga cagctcgccg gtgcgcacga gttctgcctg cgcatgcccg tcgagctcgc
      841 gcaggcgctc tgagaaagac atgccatcac cctttcgaaa tagctttcaa taaagctttc
      901 ttgcgagatg ctagcttctg gtgcggggtt catcaaccga cgaccgggcc ttggaccgtg
      961 tgtcctgggg tggaaaatcg gacagatgcc cccatgaggt tggccacccg gaccgacctt
     1021 tgatgagatg cgcgtcagaa ccaggccctg gcaaggcgcg gcaggcgcgg cacaccgaac
     1081 cgccgcgcgg gaggcgaaac atgaacgaca gagctccggc cggcaacgcg atcccactgg
     1141 accggctggc ccgccaggcg acccggctgg cgcagctcgt gaacgcggcc acccgggcgg
     1201 cctcggcctc ggccggcctc actcatgcgg atacggacgt actcctggcc ctgtacggcg
     1261 cgccggagca ccggctccgg cccaccgcgc tgtccaccgc gtgcaacctc tcctcgggcg
     1321 gcacgagcaa tgtcatcctc cggctgatgc aggccggata cgtgaaccgg gaagccgacg
     1381 cgtacgacgg ccgcagcacc tgggtgcaac tcaccatgga gggagaggca ctcgcgtcct
     1441 cggttctgga atcagccaca gcggcgcacg cccggctcct cgaccggttg cccggcggca
     1501 tcgccgtcgc gctcgacgaa ctcctggaga tcgccctcgg ccacctcgac gacggcgcag
     1561 gccgctagcc tggcccgccg cgccttctgc cggccggcgg cggtccgttc gcccggggcc
     1621 cgccgaaggg ccttcacccc gggcggggac gccgccgcgg ccggggcggc cgccgtggac
     1681 gcgcgcgggg aggacctgga cagggcgatg agcttggcca tctgcgcccc ggtgggaacc
     1741 ccctcgacgc ggtacccgtc ggccacgacc gtcggggcga tccgtacgga ccgccgcggg
     1801 gtcaccgctt cctggtgcct tcgtacgtag tagggcgagc gcaccgccgc gcggaagcgc
     1861 tccgggtcga gcccggcgcg ccgggcggcc tcggccagca ccgcgaggtc cgcgatgtcc
     1921 tgaccctccg tgaagcgcgc ggagaagacc tggtcgctgt acgcgtcgcc gcgcccgtgg
     1981 tccgccgcgt actggtagcc ctggagggcg aggcggctgg acgtgttcgc gggggcgacc
     2041 gggctcaccc gtacccccag ccggtcggcg agcggacgca gaccgcggtc ccagcgctgg
     2101 gccgaccaca ccgggtccca ggctccgcgc cggctttcat ggggatgcca ccgcacctga
     2161 acaccggagc ccgcgagctc ctcggtcagg aagtgacggg tgatcatact ggacgggcat
     2221 ccgtagtcga accacgagtc aatcccgaca gccatcgcta gtgggcgcct tcctgcacct
     2281 gggtgctgtg ctctgttggc cggtcacctc tggtgctcca tggcggactt gcaccgcccg
     2341 gccatagaac cataccttca tcccggtttt caatcagcta ccggtattgg ctcagcggcg
     2401 ccttaacagc ggctctgagc agcggaaata caagaacgtg aaccccgggc gtcgagatta
     2461 tggacagctt ctccggccca ttcgcggtga agatcctgac caaatgcaga ccgaggggtc
     2521 ttgttctgtt ctccgtgcgc ggttcaggta cggactcggg gacacccgag ccggcccgga
     2581 gtccggaccg gcggacccac ggagggcaga tcgggttcac tcacacacgt gggccggttc
     2641 ataagtcccc ctgctcagct ctttcttcgc cagcgccgcc gaatctacaa accgtgccgc
     2701 cggtttgtca aaggctcatc ggggtcgata tcgggcacgg aacgtgagca tcgatgccct
     2761 ccatgccctt tatgccagga gaaataaccg gggatgcggg taaataccgg acacgccccg
     2821 acgagcccgc ttcacggtgg gtgaggaatt gaccctcccg taacccccat atgaacaggt
     2881 tgaagccaac caagtggact gtttcgcggg ggcagtgcga ggctgtcacg gcgacctcga
     2941 cgcgtgcggc gaccggcacg cggaggcctc gcggaggcgc cggggagggg tgaccgatcc
     3001 agccacgggc gtgaatctga tccacttcga gtgaagataa taccaacgat gcggtttaat
     3061 attccctgta aatcttcctc aggagctccc cgtgaccaaa caggaacggg ccgtacgcac
     3121 ccgccacgca ctgctcaggt cggcagccgc agcgttcgat cagcgcggat acgccgcagc
     3181 cacactgagc ctgatcagca acggtgcggg agtgagcccg ggcgccctcc acttccactt
     3241 cgagaacaag gccgccatcg ccgcggcggt cgaactcgaa gccgccgaca ccctttgcat
     3301 ggtcgccacc cacgtgtaca tgcggcaggg atccgcgctc caggcactgg ccgacacctc
     3361 ccacgcgctc gcccgggcct tcaccaccga cgtggtggtg cgggccggct tccagctcgg
     3421 ccgtgaggcg gcctacgtca gctcgctcga cctgcacaaa gactgggagc ggtacgtcca
     3481 ccggctgctg gccagggccg ccgagcagaa caccctgcaa ccgggcctgt cgcaccggca
     3541 gatggcggcg atggtcgtcg cggccaccgt gggcttcgag gtgctcgggc agggcgagcg
     3601 ggagtgggtg tcggcgcatt cgctcaccag tttctggcgg ctgatcctgc cctccctggc
     3661 cacccccgag gccctgtgcg agctggatcc cacgggcggc cgcctcggcg tgatgtcccg
     3721 gtcctgaccg tacgcacgac gaccgggccg acgggcgaac acaaacagcg ccaccggttt
     3781 ttccggcgga cggaccacca gacgggcaga aataaacaga ccgtccggtc ttttactaga
     3841 agccctttct tccagcgcga accatacgaa agggccccgg gcggtacgcc cagggcccac
     3901 gattcgaacg aacggtgcgc cggcccgcac cccgggccgg tacccgccta caccgccgcg
     3961 gcgtcccgcg ccggctcctc cccggccccg gccaccgccc cggccccggt ttcggccccg
     4021 gcttcggccc cgatttcggc ctcgtcctcg cagtcctcct gggcccgggc ttccaggagc
     4081 ttgatctcct cgacgacccg gtcgccgcgg tccgccgcca tgtccaggcg cgcgaggacg
     4141 gcgggcgtcg cgatgcccgg gtagaggtgc tggtagagcg ccgagaccca gcgctccatg
     4201 tcctcgcggg cgctgagcgt ctgcgagtag acctggacgc cggtccagga ggcggacatg
     4261 atccacgccg tctcggcggg gttcacgtgc ggcagcaact ccccctgcgc cttggcctgg
     4321 gccagcagtt cctccacgac gccgatccag ccgggcaccg agccgccgcc gaagatctcc
     4381 cgcatctcgg gctccagcga cagccgtgcg cccgcgctca gcaggggctg gcgccgcatc
     4441 cggtgcgcga ggaccatcgc cacgtcgaag agctcctgga gcttgctctc ccggggcggg
     4501 actcccccct cgacgaactg ctcgtcgagc acgccctggg ccagctcctg cttggagcag
     4561 aagtggaagt acagcgcccc cttggtgacg cccgccctgg cgaggatgtc cgcgatcgtc
     4621 gcggcttcgt acccgcgctc gtcgaagacc gccgcggccg cttccaagat cgcgcgccgc
     4681 gtacgaaccg cacgctcctg ccgagccaca ttgcctccga gtgttcgagt gcttcgagta
     4741 cttcgagtgc ttcgcgggtc cgagtgcacc cattaaaagg aaccagcagg tccgtatttt
     4801 atcaacaaga acgacaagtc ttgacaccgg aatcgccttg taaacaaaac cggaaagtac
     4861 atatcttacg aggagtgctg tcccatccgt cgaacgactg tgtggagagg tcaatgaccc
     4921 tgttcacgtc tgagaactat gccccggcgt tagcccagga agccggcgag ccgtggacga
     4981 gccccgcaga gctcccgcag ctgacgagta ccgtgccccg agagtacgtg caccgcagct
     5041 ccgtcgccga agtcttcctg accggttaca agcgcatcga cgacaacgtt ttcctgatcg
     5101 gcggtcagtg gccgcgggcc cacaccttct tcaccggcgt cgacggcagg agccacgacc
     5161 cggtccaggc cgccgagacc ctccgtcagg ccggtctcct gctgtgccat tcggaatatg
     5221 gagttccact gaagcacaag atgcttctgt ggaccctgga tttcacggcc gatccctcgc
     5281 agctgcgcat cgggaccagc cccaccgaac tcgaaatcct cgcgacctgc agggatttcg
     5341 tctggaaggg cagcaagttc tccggcgtcc tcgaagtcac catccgctgc gacggcaggg
     5401 acgcggcctc cgggaccgcg acgttcagct gtgtctcctc ggccgtctac cgccgcctgc
     5461 gcggtgaggc cggtttcgag tccgcgctgc ggccgctgcc gcgccagact cccgtcccca
     5521 ccgccgaggc cggccggctg ctcgccgccg acgtcgtcct cgcgcccgcc gaccggcccg
     5581 gccgctggct gctgagcccc gacctcggcc acccgatcct cttcgagcac gccaacgacc
     5641 accacccggg catggtcctg gtcgaggccg cccgccaggc cgcgtacgcc acgctggccg
     5701 gcgccgcctt caccccgacg ggcatcgaga ccgccttccg cagctacgcc gagttcgacg
     5761 ccccctgctg gatcgacacc gagctcgtcc ccaccgacga cccggcggtc cgcagggtgc
     5821 gcgtgaccgg acaccaggac gggcgcacgg tgttcgagtc gaccgtcacg ggcgcagtcc
     5881 ccgttctctg acccggcgcg gccgggcctc gccccgggcc ggcggggccc gacacgatca
     5941 tctggaggtt ggctgtgcga gcgtcactcc ccgtcgcggg gaacagctcg ggggtgctcg
     6001 ccggcaagtc ggccctgatc acgggggcga gttcgggcat cggggcggcc gccgcccggg
     6061 tgttctgccg ggagggcgcc cgggtcaccc tggtggcccg ccgggagccc gaactcgctg
     6121 ccctgacggc tgagttgacc gccgccggac atcaggcgca gtacgtcctc gccgatgtca
     6181 cccgggccgg ggacgcggtc cgcgcggtcg ccgccgccgt cgaggcctac gaccgtctcg
     6241 acgtggcctt caacaacgcg ggcctcggcg ccctcccggg ccccatgcac ctccaggacg
     6301 acaaggtcta cgacgaggtc atggacgtca acgtgcgcgg ggtgtggaac tgcatgcgcg
     6361 ccgagctgac cgcgatgctg gagtccggcg gcggcgccat cgtcaacaac agcagcaccg
     6421 cggggctcgt cgccacggcg gccggctccc cgtacatcgc gtcgaagcac gcggtgatcg
     6481 gcctgaccaa ggcggccgcg aaggagtacg cgcagcaccg catccgggtc aacgcgctcg
     6541 ccacgggcgc cacccgcagc gagatgatca ccggctggat ggccgaggac ccggcgcgtg
     6601 agcccgcgat ggcccagaag gcgatgctga ggcggctcgc ggagaccgag gagatcgcgg
     6661 aggcggcggt ctggctgtgc gccgaccggt cctcgtacgt caccggtacg acgctggccg
     6721 tcgacggcgg ccgcctgtcc cactgacccc ccgcttccag agacgccccc agcccgcccc
     6781 tcagcccgcc tgcggcccga actcccccgt cagcagcagc ttcttctgcg gcttgcccat
     6841 cgcgttgcgc ggcaccgccg ccacgaagcg cacctcgcgc ggccgcttgt ggacggagag
     6901 gtgcgcggcg acaaactccg tgagctcggc gcccgtcacc ccctcggcga cgacgaaggc
     6961 cacgatccgc tgccccaggt ccgcgtccgg aacgcccacc accgcggcct cgctgacccg
     7021 ggggtggtcc agcagcgcgt tctcgatctc gcccgcgccg atccggtagc cacccgactt
     7081 gatcatgtcg atggaggccc ggcccacgat gcggtgcacc ccgtccgccg ggtccacggc
     7141 cgcgatgtcc cccgtacgga accagccgtc ctgcgtgtac gcggcggcgg tcgcctccgg
     7201 gcggcccagg taccccgaga acaacgtcgg cccggtgagc tggagttccc cgatctcggc
     7261 acccgtctcg gccgcgatcc gggtacggat gccgggcagc ggggtgccga ccgtgcccgg
     7321 ccggacctcg ccgcccgcgc ggccgctgac ggtgatcagc gtctccgtca tcccgtagcg
     7381 ctccacgggc cgcagcccgg tcagccgttc caggtcccgg aacaccggcg cgggcagggc
     7441 cgcgctcccc gagaccagca gccgcgcccc gccgagcgcc tcggcggccg gcgcgtcggc
     7501 ggcgatccgg gaccacacgg tgggcactcc gaagtacagg ctcccgcccg cctccgcgta
     7561 ggcctgcggg gtcggccgcc cggtgtgcac gagacggctg ccgctgcgca gcgccccgag
     7621 cacgccgagc accagcccgt ggacgtggaa cagcggcagc ccgtgcacca gggtgtcctc
     7681 ggcgctccac tgccaggcct cggccagcgc gtccaggtcg gcggcgatcg ccgcaccggt
     7741 cagcaccacc cccttgggcg cgccggtggt accggaggtg tacagcacga gcgccggatc
     7801 ctcgggagcg gccccaggag cggccgccgc cccggccccc ggccccgccg aaccggagga
     7861 gcgccggtcg aagtccacgt cggtcagcac cgccccggag tcccgcagga tgtgctcccg
     7921 ctcggcgggc ccggcatcgg gcggcagcgg tacgaagggc accccggcca gcagcccccc
     7981 gacggccgcc gcgacggtct ccagcgaggc cgtcgccgtc accgcgaagg cgggggcccc
     8041 ggccacgtcg gcggccaccg cgcgcgccgc gcccagcagt tcctcgtagg aggcggtccg
     8101 tccggcgacg ctgagcgcgt ccttccggtc tccgtacacc ccatccagcg cggtcagcac
     8161 gcgaagcctc ctcggtcact ccggcaacac aggagcccag gctacggcgc cggtcgcaca
     8221 cccggacggc ccgggcacct tctccccggg ccgtccggca cttcagccgt gcgtcagccg
     8281 tgcttcggcc gtgccggccg cgcgtcggcg gagcgccgcc ggcgcgcgat cagatgacgc
     8341 cctgcgccag catcgcgtcc gcgacccgct cgaagccggc gatgttcgcg ccgacgacgt
     8401 agtcccccgg cgccccgtac cgctcggcgg tctcgtgcgc gacggtgtgg atggaccgca
     8461 tgatcccggc cagttcgtcc tcgacgcgct gctcgctcca ggcgacccgc cccgcgttct
     8521 gggccatctc cagcgcgctc accgcgaccc cgcccgcgtt ggcggccttg ccgggcccga
     8581 acgcgacccc ggcctcctgc aggatccgta cggcctcggg ggtggtgggc atgttggcgc
     8641 cctcggagac cgccttgacc ccgcccgcga cgagggcgcg ggcgtcccgc gcctccagct
     8701 cgttctgcgt ggcggagggg aacgcgacgt ccgccgggac gtcccagacc cggcccccgg
     8761 acacgaagcg ggccgaggac ccgcgccgcg ccgcgtactc gctgacgcgg ccgcgctcga
     8821 cctccttgat ctgcttcagc agggcgaggt cgatgccctt gtcgtcgacg acgtagccct
     8881 cggagtccga gcaggtcagc gggttggcgc cgagccgctg gagcttctcg atggtgtaga
     8941 gggcgacgtt gccggagccg gagacgaccg cgctcaggcc gtccagcgcc tcgccccgga
     9001 cggcgagcat ctcggcggcg aagagcacgc tgccgtagcc ggtggcctgc gggcggatcg
     9061 cggagccgcc ccagccctgg cccttgccgg tgagcacgcc ggcttcccag cggttggtga
     9121 tgcgccggta ctggccgaag aggtagccga tctcccggcc gccgacaccg atgtccccgg
     9181 cgggcacgtc ggtgtgctcg ccgatgtggc ggtgcagttc ggtcatgaag gactgacaga
     9241 agcgcatgac ctcggcgtcg gacttgccgt gcgggtcgaa gtcgctgccg cccttgccgc
     9301 cgccgatccc gaggccggtc agggcgttct tgaagatctg ctcgaagccg aggaacttca
     9361 ccacgccgat gtccaccgac gggtggaagc gcaggccgcc cttgtacggg ccgagcgcgc
     9421 tgttgaactc gacccggtag ccgcggttga cgtggactcg gccccggtcg tcctgccacg
     9481 ggacgcggaa gaggatctgc cgctcgggct cggtgagccg ctccaccagc gccacggccg
     9541 ggtcggcgta ctcggggcgg gcggcgaaca cgggggccag ggtctccagt acttcccgta
     9601 ccgcctggtg gaactcgggc tgcgccgggt tgcgccgctc gatgtctgcc cgcagtgctt
     9661 ccagcctgtc cttctgatcc ttcacgtgtg tccctccagg ggttccgtgg ttccgtgctt
     9721 ccgggctgcg gaaacgttct tccgtatcgc ggttcccaaa cgggaggcta ccgcgcgatg
     9781 ccccggccgg aaacatcctc atcgatcaca cccggcagga agctttccta ctcataagac
     9841 caacagcctt gacgattaga tgacctgcgc atgaccagcg gcagaccgga agaccagccg
     9901 cagaccaccc gcgggcgggt ccgccggggt ccgtgaccgt gatcggaacg ggccaacggg
     9961 cccgccgcgc ttgccagtag ggtgccgtca tgagcacctc cccactgcgc ctggagccgg
    10021 tcaccgtggc gaacttcgac acggtgtgcg cgatacaggt ccgccccgac caggcacatc
    10081 tcgtctcacc cgtggtcaag tccctggccg aggcctatgt caacggcgac tgcgcctggc
    10141 cgcgcgccat cgtcgacggc gacgaggtcg tcggcttcgt gatggccttc atcgacatcg
    10201 cctggaaccc ggccgcggac cccggcgaca tccgctccgg catctggcgc ctgaacatca
    10261 gcgccgaccg ccagggcaag ggctacggcc gcttcgcggt cgaggccgtc accgccgaac
    10321 tccgccgccg gggcgccgac cgcgcgtacg tcacctggga accgggcccc ggtacgccca
    10381 agcccttcta cctcggcctc ggattccgct ccaccggcga gcggagcggc ggccagtccg
    10441 tcgccgtact gcccctggcc gccgggcagt acgacgcggt ggacgcccgc taggctccgg
    10501 gcagtacgac cgtccgcgcc gcccccggca tcagcggtgg gacgggctgg gcaccggcgc
    10561 ccgtccggaa ctcctgcgga ctgacgcccc ggacccgctt gaaggccgtc gacagcgcga
    10621 acgccgatcc gtagcccacc cgccgggcca ccgtcgccac cgtcgcgtcc ggctcccgca
    10681 gcagatccgc ggcgagcgcg agcctccagc ccgtcaggta cgccatcggc ggctccccga
    10741 ccagctcggt gaaccggcgt gccagcgagg cccgggagac cccggccttg accccgagct
    10801 cctccaccgt ccagccgtgg gccgggttct cgtggagcat ccgcagcgcc gggccgacca
    10861 ccgggtcgcc ctgcgcccgg taccaggccg g
//
