LOCUS       NZ_BMVE01000015        48439 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces goshikiensis strain JCM 4640 sequence15, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVE01000015
VERSION     NZ_BMVE01000015.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 189377)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650555.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:30:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,491
            CDSs (total)                      :: 7,410
            Genes (coding)                    :: 7,286
            CDSs (with protein)               :: 7,286
            Genes (RNA)                       :: 81
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 44 of 125
            Pseudo Genes (incomplete)         :: 101 of 125
            Pseudo Genes (internal stop)      :: 9 of 125
            Pseudo Genes (multiple problems)  :: 27 of 125
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 96819
            Orig. end                         :: 145258
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVE01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..48439
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="3"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..48439
                     /SMILES="C1=CC(=O)C(N)C=C1C(=O)C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..48439
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:28439](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..28439
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..48439
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:28439](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      20001..28439
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     misc_feature    complement(304..319)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.3"
                     /tool="antismash"
     gene            555..1439
                     /locus_tag="IE248_RS31660"
                     /old_locus_tag="GCM10010336_64460"
     CDS             555..1439
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735059.1"
                     /locus_tag="IE248_RS31660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64460"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190032451.1"
                     /transl_table=11
                     /translation="MNGTSQLGDFLRSRRSQLRPDEAGVPTYGERRRVPGLRREELAML
                     AGVSASYYARLEQGHSLGASPEVLEAIAQALRLDESERRHLHDLARSAKPRSRRRPAPE
                     LVTEPTAQLLDALGDIPAIVIGRRSDVLAWNRMGHALFAGHLDPGAPEVPAERPNMARL
                     VFLDAHTRDLYADWPGKAKAVVGNLRLVAGQYPQDSALHTLLGELSAKSEDFASMWADH
                     RVKACAVADYEMRHPLVGSLTVMQQTLSQGPGPGIVVATTAAGSPSRAALDLLAQAVAR
                     TAPARPDSRLSTG"
     gene            1573..2538
                     /locus_tag="IE248_RS31665"
                     /old_locus_tag="GCM10010336_64470"
     CDS             1573..2538
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735058.1"
                     /locus_tag="IE248_RS31665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64470"
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="WP_190032452.1"
                     /transl_table=11
                     /translation="MFTKFSKAAVSAAVLASAAVAMATAAPASAVSAPLKCARTAVHFD
                     LAKGQTPENVTLAPDGTAYVTLAKARQIAAVSRGGSVRILATLPEPADGGVHTPALGFP
                     LTTGIVRAHDGTLYFLYATGTADLTGVWRLRPGGRPQRIAALPATGLPNGLALEARTHT
                     LYITDSVLGTVWRVPASGGTATTWSTDPALAPTGFLGANGLKIHNGALWATNLDKGTVL
                     RIPILADGRAGTARVTATGLPGIDDFAFTGHGDQIIAALNTVNQVALIQPDGLHTTVLT
                     AADGLQGPTSIALRGDTVHVMSAAYLTAKDPNLILAHLGG"
     gene            2564..2905
                     /locus_tag="IE248_RS31670"
                     /old_locus_tag="GCM10010336_64480"
     CDS             2564..2905
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE248_RS31670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010336_64480"
                     /product="hypothetical protein"
                     /protein_id="WP_190032453.1"
                     /transl_table=11
                     /translation="MVIALPGQASAAEISCIVNSVAVSGSTISGTSGDDTIRCYEGVAR
                     GVSIEAGAGNDTIFGEATAAPDALAESPAWATTGPSPATSPPSTAPPAPPSPDPAAHTA
                     GGGADHGLT"
     misc_feature    2576..2578
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2898..3569)
                     /locus_tag="IE248_RS31675"
                     /old_locus_tag="GCM10010336_64490"
     CDS             complement(2898..3569)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735053.1"
                     /locus_tag="IE248_RS31675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64490"
                     /product="hypothetical protein"
                     /protein_id="WP_190032454.1"
                     /transl_table=11
                     /translation="MSGNRRKAFLVSAALIGGAMLMTACQDSDATTDTGAAPGSSASAP
                     AGKAGAPSGSPAPASKQGNAKGADATGKGTAAGSGAATGNSGQKPVGQVCGAGDIAWST
                     KSESQAGGYILITAKAKPGITCYLPAALPTVAFGSDGTEAGPAEQSVGKQIKLSGSTAA
                     YAGVNPKTTKENGGKELDSIIVAVGNNDPDPVSLPVGTITVDRPVVTNWHTSPKDAVPV
                     R"
     misc_feature    complement(3692..3709)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.84"
                     /tool="antismash"
     gene            complement(3927..4694)
                     /locus_tag="IE248_RS31680"
                     /old_locus_tag="GCM10010336_64500"
     CDS             complement(3927..4694)
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720962.1"
                     /locus_tag="IE248_RS31680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64500"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_190032455.1"
                     /transl_table=11
                     /translation="MTTITTRTVEYPADGLTMIGHLALPAGVDRRPAVLLGPEGMGLSD
                     VERQRADALAELGYVALAFDLHGGRYLGDPEEMLARCLPLLADPDRMRGIGHAALDVLR
                     TEPRTDPDRIAAVGYGTGGAVGLELGRGGVSLRAIGTVNATTTGRPGESARIGCPVWAG
                     VGSEDPIMPPAQRNAFTAEMQAAGVDWRLTVYGGALHAFHHPPVDHPVVPGVGYHPRHA
                     QRAWRDVVDLLAECLPVTEDLGHDPGEHADPGH"
     misc_feature    complement(4682..4702)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            complement(4795..5661)
                     /locus_tag="IE248_RS31685"
                     /old_locus_tag="GCM10010336_64510"
     CDS             complement(4795..5661)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735048.1"
                     /locus_tag="IE248_RS31685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64510"
                     /product="NmrA family NAD(P)-binding protein"
                     /protein_id="WP_190032456.1"
                     /transl_table=11
                     /translation="MIVVMGATGATGNALLRSLLALGTPVRALTRTPHRPIPGTTGAHQ
                     PPVEVQYADAADPHSLRTAFKGAGQLFLAMANSPAQVELETRVIDIAAHTGIGHIVKIS
                     APAAEPDSPVAISRGHHAVEEHLRASGLTHTVLRPYAFMQNLLRLAPTVAQGVIVGTMG
                     DAPCNYIDCRDIGDVAAAALTRPDIAGGTYALTGPEAVAYPELASRLSTLTGNQIRYVN
                     LTPDELRANLIHHARMPTWLAQHVTEIQQLAIARPETPTTTVTDILGRRPRTLDAFLHE
                     QHAHFRR"
     misc_feature    5647..5662
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     gene            complement(5763..6227)
                     /locus_tag="IE248_RS31690"
                     /old_locus_tag="GCM10010336_64530"
     CDS             complement(5763..6227)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735045.1"
                     /locus_tag="IE248_RS31690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64530"
                     /product="hypothetical protein"
                     /protein_id="WP_190032457.1"
                     /transl_table=11
                     /translation="MPATKDRTSRNRASSRPFILWREVLTAYAAPALMAGTAGVVTGQR
                     DLAVAACTSIAGTSAVVAFLVGTWLRHGGRPRRWTTTTPRVVLTAALVIATVGAAALLG
                     WLTSQWLPAHTPIPATPWLERLRIDLPVSAALATTIVTLRWRSTAAASPA"
     gene            complement(6374..6892)
                     /locus_tag="IE248_RS31695"
                     /old_locus_tag="GCM10010336_64540"
     CDS             complement(6374..6892)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735044.1"
                     /locus_tag="IE248_RS31695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64540"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_073795690.1"
                     /transl_table=11
                     /translation="MTRDDTDGEAPTLDQARRQVEHYGLEVDPQAVLVAVRLISAGARV
                     GRAAEAHFAKFGLSTGRYRLLADLEDHGGEKSPSRLALDLGVSRATVTGLLDGLERAGL
                     IARRPSTEDGRGTVAILTARGAQLLRDMASEHFGRLEAMVSGLSVEERAVFLDLLARVV
                     RGSAALTAD"
     misc_feature    complement(7022..7035)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.75"
                     /tool="antismash"
     misc_feature    complement(7023..7036)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.76"
                     /tool="antismash"
     misc_feature    complement(7027..7040)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.86"
                     /tool="antismash"
     gene            7051..7509
                     /locus_tag="IE248_RS31700"
                     /old_locus_tag="GCM10010336_64550"
     CDS             7051..7509
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735042.1"
                     /locus_tag="IE248_RS31700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64550"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_229895670.1"
                     /transl_table=11
                     /translation="MSRQDTATGASAAIGAALYGLATRAARRLPRDMSLTSAATLATLD
                     RTGPRRITDLAAVEGVTQPAMTALVRVLEESGLVERQGDASDKRVTLVCLTEAGASYVR
                     TRRQAGVHAFERLIGELTGDEVDALVSALPALKHLAELESQDREEPKR"
     gene            7506..8939
                     /locus_tag="IE248_RS31705"
                     /old_locus_tag="GCM10010336_64560"
     CDS             7506..8939
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040870.1"
                     /locus_tag="IE248_RS31705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64560"
                     /product="MFS transporter"
                     /protein_id="WP_190032458.1"
                     /transl_table=11
                     /translation="MTGRPVGGVAVDAFPAARSEARLLVPALTFIALVVAAVASLGTPL
                     ITSAATSFHVSLGSAQWTLTIALLSGAVATPLLGRLGAGPHRRATILATLAVVVAGSAL
                     TVLPLPFAWLLAGRAAQGVGLGLTALMMGVARDHLPEERGAAVIALISVVSIIGAGVGY
                     PLAALLAELGGVRAAYGLGLVVTAAALLTAWRFMPEAPEGRSTHVDVAGAVVLAAALLL
                     VLFLAGERNLWSRHLAVAAGLAVVALVLLCVWAVIELRSTTPLVDVRAVRHPAVAGANL
                     AMFVGGIGMYLLLTLITRYAQTPHGAGYGFGLTTFVAGLVLIPFSVLGFVAGKLTPRIR
                     TRIADPLLLAGSAVVVGGGFALFAAARSDLAELFAAMGVLGFGVGGFSAAMPGVILAVT
                     PKSETSSAMSFNYVVRSVGYSLGSAIGGLILTAGTGPGHLFPDDSAYTTAALVGIGAMA
                     ITTLTSLALARRRSSETNP"
     gene            8973..9266
                     /locus_tag="IE248_RS31710"
                     /old_locus_tag="GCM10010336_64570"
     CDS             8973..9266
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987675.1"
                     /locus_tag="IE248_RS31710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64570"
                     /product="DUF1330 domain-containing protein"
                     /protein_id="WP_008735038.1"
                     /transl_table=11
                     /translation="MPKGYWVSAYRTISDPEKLAAYNKLAPAAVKAGGGRVLARDGRIV
                     AHEAGIAERTILIEFDSFEQAVAAHESAAYQEALAALSDGVERDFRIIEGTD"
     gene            complement(9444..10433)
                     /locus_tag="IE248_RS31715"
                     /old_locus_tag="GCM10010336_64580"
     CDS             complement(9444..10433)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735036.1"
                     /locus_tag="IE248_RS31715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64580"
                     /product="aldo/keto reductase"
                     /protein_id="WP_190032459.1"
                     /transl_table=11
                     /translation="MTTNVPTRHLGSLAVSAQGLGCMGMSHGYGASDDAQSIATLHHAL
                     DRGVTLLDTADFYGAGHNEELIGRAVAGRRDEVVLATKFGFANRLGEPTLVRGDAAYVR
                     QACEASLRRLGVDHIDLYYQHRVDPQVPIEETVGAMAELVQAGKVRHLGLSEAGASTIR
                     RAHAVHPITALQSEWSLWTRDLEAEIAPVCRELGIGLVPFSPLGRGFLTGRYSSVDGLA
                     ETDVRRSQPRFADGNLERNLAIVARIDELAAAKGVTTGQLALAWVQHRGDDVVPIPGTR
                     RRQYLEENLAALAVELSPGDLAAIEAAAPSEQIAGTRYDATSLTFVNN"
     gene            complement(10910..11365)
                     /locus_tag="IE248_RS31720"
                     /old_locus_tag="GCM10010336_64590"
     CDS             complement(10910..11365)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023580.5"
                     /locus_tag="IE248_RS31720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64590"
                     /product="DUF3592 domain-containing protein"
                     /protein_id="WP_037789720.1"
                     /transl_table=11
                     /translation="MSASQILLLLASVFTTAGSVIGVVASLKIRRVRFLLREGSTARGV
                     VTRLEETRIAPASDSGSTSRSVGTTVYYPVIAWSTGDGRAMETRTSIARPKDRTLPVGT
                     RVEVRYDQADPSRWTLPAEGTAFWWLFSAMGALFVAIGLGFALGVLL"
     gene            11639..13210
                     /locus_tag="IE248_RS31725"
                     /old_locus_tag="GCM10010336_64600"
     CDS             11639..13210
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (110-258). E-value:
                     4.8e-15. Score: 47.8. Matches aSDomain:
                     nrpspksdomains_IE248_RS31725_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735349.1"
                     /locus_tag="IE248_RS31725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64600"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_190032460.1"
                     /sec_met_domain="PF00561 (E-value: 9e-25, bitscore: 81.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVSPAARRALAVGLALAACLTSSPVLATAAEAPAQDSAGAGLD
                     RYYRQHLGWGSCIKGPDDTTGRDLDQAGVQCAEVTVPLDYADPRGRTITVAISRLKATD
                     TRHRIGAILLNNGGPGGPALQSPPQARASMKEVGSRYDIVGFDPRFIGRSTALDCGLPV
                     GMTWLSAGAGRAGFDRQVALQKSLADKCRATDAAVLPHITTRNTARDMDVIRASLGERK
                     ISFLGYSYGTYLGTVYTQMFPGRHDRMVLDGAINPSDYRPRLLKGTERENEKALSDWAA
                     WAAEHHDTYGLGRSRAGVLAAVDRIVAAAARAPLTIGAGADAFRIDDSQVPLLLFSGIA
                     DDTAPARASFGELLSVLAKAAEGRPTTVPPMLVPELRYVLRGEGEPTGAQSAVICGDVA
                     AARDPELYWRDIERNRTAHPLFGALTNNINPCAFWDSPREEPTRVRRDAPALIVAATGD
                     PRTTYKGSVELHEQLPSSRLVTLEGANRHALFGRYGNACVDDQVNRYLATGKLPVRDRT
                     CVKQAG"
     aSDomain        11969..12412
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31725_Abhydrolase_1.1"
                     /evalue="4.80E-15"
                     /label="IE248_RS31725_Abhydrolase_1.1"
                     /locus_tag="IE248_RS31725"
                     /protein_end="258"
                     /protein_start="110"
                     /score="47.8"
                     /tool="antismash"
                     /translation="AILLNNGGPGGPALQSPPQARASMKEVGSRYDIVGFDPRFIGRST
                     ALDCGLPVGMTWLSAGAGRAGFDRQVALQKSLADKCRATDAAVLPHITTRNTARDMDVI
                     RASLGERKISFLGYSYGTYLGTVYTQMFPGRHDRMVLDGAINPS"
     gene            complement(13247..14563)
                     /locus_tag="IE248_RS31730"
                     /old_locus_tag="GCM10010336_64610"
     CDS             complement(13247..14563)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072653.1"
                     /locus_tag="IE248_RS31730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64610"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_229895679.1"
                     /transl_table=11
                     /translation="MSVTAAVALVALGVCAAAFLVVRAALYEQLDLTLTQSARLAAQRE
                     PGAGPGVLAGECRFLAAPACAEVVSADPAKKPTEPGRLPVAPAAREVAEGKRAPYYTNI
                     TVAGYPARMLTTDYAKGRALQVALRADTVEDGIEEAARWLVLTAVVGVLLAALLGHWVS
                     RTGLAPVARLTATAERIAATRDARHRIELPPPGREDEITRLATSFNTMLGELEQSVAAQ
                     RQLVADASHELRTPLTALRTNAELLARADRLTPEQRERASAALGRQLREVTGLVNDLIE
                     LARDEEPQPLVEEVSLGALVEHCVQSARAHWPAVPFHLRAPAEPVVVPGVPARLSRLLG
                     NLLDNAAKFSRDGLPVEVDLVAGGQGRGPELSVRDHGPGIAPEDLPHVFDRFYRAGAAR
                     ALPGSGLGLAMARQIARAHSAELTAEAAPGGGALFRLTF"
     gene            complement(14629..15351)
                     /locus_tag="IE248_RS31735"
                     /old_locus_tag="GCM10010336_64620"
     CDS             complement(14629..15351)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735028.1"
                     /locus_tag="IE248_RS31735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64620"
                     /product="response regulator transcription factor"
                     /protein_id="WP_190032462.1"
                     /transl_table=11
                     /translation="MSSQDTTGSTGSAGGQRILVVDDEPEVRAAVEDGLAVEGYEVRGA
                     ADGLAGLSQVAAWEPDAVVLDVMMPVLDGLGVCRQLRAMGDRTPILVLTALDSVSERVD
                     GLEAGADDYLVKPFALDELVARVRALLRRASPAPGGAAALGVADLVLDPATRTGRRGSR
                     PLEFSRTEAALLELLVRHAGQVLPRELILELVWGQDFGPDSNSLAVYIGYLRRKLEAGG
                     EPRLVHTVHGVGYRLDAA"
     misc_feature    complement(15405..15421)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.62"
                     /tool="antismash"
     gene            15425..16615
                     /locus_tag="IE248_RS31740"
                     /old_locus_tag="GCM10010336_64630"
     CDS             15425..16615
                     /GO_function="GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_transf_28"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735027.1"
                     /locus_tag="IE248_RS31740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64630"
                     /product="glycosyltransferase"
                     /protein_id="WP_190032463.1"
                     /sec_met_domain="Glyco_transf_28 (E-value: 1.2e-25,
                     bitscore: 83.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 1.2e-32,
                     bitscore: 106.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTTPHTPTTLSVVIGAGGTGGHIYPGLALAEALRAAVPGAVVS
                     FIGTERGLETELIPGAGYRLHTVDMIPFDPSLGAKRYLLPAALLRSAHQARSVIRAQGA
                     HAVVGMGGYPSAPAVLGARLAGLPAVIHESNAVPGRANQFAARLTPHVAVAFDRSRAHL
                     SGGERALTTGMPISAALSGLAELPGADRVALRAEARYALGVPPGRRLIVFNGGSLGAVR
                     LTRAAAALAGLWQYRDDVQLLIKTGPAELPDTVTELATSGGQRIARAVPYLDRMDLVYA
                     AADLVVCRAGSATIAELAATGVPAVLVPYPYAPGDHQTHNARVLSDAGAGVLLPDAETT
                     AERLAHLIGPLLADPARLSAMAGAADPGPHARAAELLAAEVLRVAGFVPTPHLERI"
     gene            16612..17607
                     /locus_tag="IE248_RS31745"
                     /old_locus_tag="GCM10010336_64640"
     CDS             16612..17607
                     /NRPS_PKS="Domain: NAD_binding_4 (10-185). E-value:
                     6.7e-18. Score: 56.6. Matches aSDomain:
                     nrpspksdomains_IE248_RS31745_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735025.1"
                     /locus_tag="IE248_RS31745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64640"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_008735025.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1e-19, bitscore:
                     64.1, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.8e-22,
                     bitscore: 73.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.9e-17, bitscore:
                     56.6, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSWTDRTVLVTGAEGFIGSTLVDLLVSRGARVRAFVHYKPYAEK
                     GHLARYLADPDGPVEMWTGDVRDAGRVSDAVAGCDTVFHLAALIGIPYSYASPGAYVQT
                     NVTGTQNVAEACRRHGVRRLVHTSTSEVYGTALTAPISESHPLQPQSPYSASKIGADMM
                     ALSFHHAFELPVTVVRPFNTYGPRQSARAVIPTILAQLHAGSREIRLGSLTPTRDFTYV
                     TDTAEGFLAVAECDRALGEVVNLGTGEEISVGALAEALIAASGREAKVVVDPTRLRPSG
                     SEVQRLLSDNSRAREWAGWRPRVGLEEGLRHTSAWIAANQSLFAPDRYAV"
     CDS_motif       16633..16770
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31745_0001"
                     /evalue="2.30E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE248_RS31745"
                     /protein_end="53"
                     /protein_start="7"
                     /score="13.8"
                     /tool="antismash"
                     /translation="TVLVTGAEGFIGSTLVDLLVSRGARVRAFVHYKPYAEKGHLARYL
                     A"
     aSDomain        16642..17166
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31745_NAD_binding_4.1"
                     /evalue="6.70E-18"
                     /label="IE248_RS31745_NAD_binding_4.1"
                     /locus_tag="IE248_RS31745"
                     /protein_end="185"
                     /protein_start="10"
                     /score="56.6"
                     /tool="antismash"
                     /translation="VTGAEGFIGSTLVDLLVSRGARVRAFVHYKPYAEKGHLARYLADP
                     DGPVEMWTGDVRDAGRVSDAVAGCDTVFHLAALIGIPYSYASPGAYVQTNVTGTQNVAE
                     ACRRHGVRRLVHTSTSEVYGTALTAPISESHPLQPQSPYSASKIGADMMALSFHHAFEL
                     PVTVVRPFNTYG"
     gene            complement(17832..18731)
                     /locus_tag="IE248_RS31750"
                     /old_locus_tag="GCM10010336_64650"
     CDS             complement(17832..18731)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982458.1"
                     /locus_tag="IE248_RS31750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64650"
                     /product="hypothetical protein"
                     /protein_id="WP_190032464.1"
                     /transl_table=11
                     /translation="MSLAPRAVLVHRRTEYEELLARYGTHGQAAFLLSRRGRSIDEVVH
                     RHERTRQALREVAAAVPLTWRSSSVERADLDRFPFAPEDVVVVVGQDGLVANTAKYLRG
                     QPVVGIDTDPGRNPGVLVRHRCADTAALLRAAIAAGSRAEELTMVEAVADDTQRLLALN
                     EIYLGSPGHQTARYRLGGEGDQGPEEAQASSGVLVGTGTGATGWLRSLWLERGSSAGLP
                     SPCERRLLWFVREAWPSPATGTTRVAGELGQGQGLRLTVESDRIVVFGDGMEGDALELT
                     WGQSVRLGIAGTSLRLVT"
     gene            complement(18728..19741)
                     /locus_tag="IE248_RS31755"
                     /old_locus_tag="GCM10010336_64660"
     CDS             complement(18728..19741)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513180.1"
                     /locus_tag="IE248_RS31755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64660"
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_190032465.1"
                     /transl_table=11
                     /translation="MADITRRFGWRHLRSAPTAHIRHHKRGQLVHDGPGLSFWYRSLSA
                     ALSEVPVEDRELAMAFHARTSDFQDVSVQASVTYRISDPAEAAARLDFSVDPDTGSWRG
                     APLEQIATLLTETAQQHTLDVLARTPLAVALVDGVASVRGSVTAGLAAEPRLPATGIDV
                     VAVRVVAIRPEAEVERALRTPAREQIQQEADRATYERRAVAVERERAIAENELASQIEL
                     ARREEQLIDQRGTNARREAEEKAAADGIRTETEAARKVRLARADAEAARETGAARAEAQ
                     AAWLRVHDEAGPRTLHALAATRLAENLPRIDSITLSPDVLTGLLARLGRPEGGADA"
     misc_feature    19756..19776
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: medium, score: 28.35"
                     /tool="antismash"
     misc_feature    complement(19789..19809)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: medium, score: 25.83"
                     /tool="antismash"
     gene            20001..28439
                     /locus_tag="IE248_RS31760"
                     /old_locus_tag="GCM10010336_64670"
     CDS             20001..28439
                     /NRPS_PKS="Domain: CAL_domain (170-484). E-value: 6.4e-97.
                     Score: 316.7. Matches aSDomain:
                     nrpspksdomains_IE248_RS31760_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (570-639). E-value: 1.6e-23. Score:
                     74.8. Matches aSDomain: nrpspksdomains_IE248_RS31760_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (671-1095). E-value:
                     8.8e-184. Score: 603.2. Matches aSDomain:
                     nrpspksdomains_IE248_RS31760_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1204-1495). E-value: 5.7e-102.
                     Score: 333.0. Matches aSDomain:
                     nrpspksdomains_IE248_RS31760_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (1615-1796). E-value: 5e-51.
                     Score: 165.3. Matches aSDomain:
                     nrpspksdomains_IE248_RS31760_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (2166-2345). E-value: 1.4e-55.
                     Score: 180.0. Matches aSDomain:
                     nrpspksdomains_IE248_RS31760_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2435-2521). E-value: 9.2e-24.
                     Score: 75.6. Matches aSDomain:
                     nrpspksdomains_IE248_RS31760_PKS_PP.1"
                     /NRPS_PKS="Domain: Thioesterase (2598-2806). E-value:
                     2.9e-29. Score: 95.1. Matches aSDomain:
                     nrpspksdomains_IE248_RS31760_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433743.1"
                     /locus_tag="IE248_RS31760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64670"
                     /product="type I polyketide synthase"
                     /protein_id="WP_229895671.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-90, bitscore:
                     297.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 5e-227, bitscore: 747.1,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.8e-96, bitscore:
                     315.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.6e-101, bitscore:
                     333.0, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.4e-58, bitscore:
                     191.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.4e-14, bitscore:
                     45.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 4.5e-20, bitscore:
                     66.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTDADIVRPLPVLLREHARSIGEQVAFEDRRTRLTYRDLERRTR
                     RLAGHLAGLSPARGERVAILLGNRVEAVESLLAVTRASAVGVPLDPGGSGPELAHLLDD
                     SGARVIVTDPARLSRLRPLLAARPGLTVLVVEEAEEIEEVEEPPGADPDGEPDGHPQPG
                     SAETVQLRYEDLVGTEPRTPAPDDLGLDEVAWLLYTSGSSGTPKGVLLTQRNRLAPVAA
                     GLVGVLGMSRQDRLLWPLPLHHAMSHVVCVVGVAATGASAMIPPRFTVAEVLAQLRRTD
                     APYTLLGGVPTTYSALLDEVRAEAARHPGQGDGDMGPGAGPGLGAPALHGCVSGGASAG
                     PAFRRSFEEVCGVPYLEHYGSTEAGPVTMAAPGDTTAAESCGRVLPGTRVRVGGGADGQ
                     DVGEGELWVSGPGVTPGYHGSAQATAEVLRDGWFRTGDLARVDAGGELVITGRASDLII
                     RGGANIHPSEVEAVLRHLPGVADAAVAGRPHPAFGEVPVGYLVPERGRVLDRAALLAAC
                     RRELSLFKVPAALYEVEGIPRTASGKVRRHALADLPGRLLDGTAPAAEAGADVLALVRR
                     AVADVLGCAPGEVESGTALRDLGMDSLTATVLRERLSAATGLPLSEAVAFDFPTVAALA
                     AHLGTLGAAGPAPLEPGPDPAKARSDGDDGHHDDDPVVIVGMACRYPGGVSTPEELWRL
                     VADGTDAIGPFPADRGWDTEGLYDPDPGRPGRTYVREGGFLRGADRFDPGFFGISPREA
                     LAMDPQHRLLLEVAWEAFERAGVDPRALRGSTTGVYAGLMYSDYAARFAVTPAQVEGYL
                     GIGNAGSVASGRIAYTFGLEGPAITVDTACSSSLVALHLAAQALRRGECALALAGGVTV
                     MSSPASFVEFSRQRALSPDGRCKAFGAGADGTGWAEGAGMLLLSRLSHARRTGLEVLAV
                     VRGSAVNQDGASNGLTAPHGPAQQRVIRQALADAGLAPADVDAVEAHGTGTRLGDVIEA
                     EAFLAVYGRESRQRPLWLGSVKSNIGHTQAASGVAGVIKTVQAMAHGVLPRTLHADEPN
                     PAVDWPSGQVALLTRPEPWPEADRPRRAGVSSFGISGTNAHVVLEEPPPQDRAQAPGPT
                     PPATPVPVPFVLSARTRAGLRDQARRLYEHVSAAPDVEPVDIGYSLATTRSAFEHRAVA
                     VARDRAELLASLRALAGGGGRRPGTHTGAARRPGPLAFLFTGQGSQRLGMGAQLYGQRS
                     LHPAFARSFDESCALFDPLLPRPLRDVVFAHEDSEAGALLWTTRFAQPALFALETALFR
                     LLESWDVRPDLVAGHSIGEVAAAHAAGVLSLADACTLVAARGRLMDALPGGAMAAVAAG
                     EDEVAAHLAQARGAVEIAAVNGPAAVVVSGDEAAVRETVAYFRDRGRATAPLRVSHAFH
                     SVHMEPMLAEFAEVVRGLSFTDPAIALVTAVAGRAATDEELRAPEFWVDHVRRPVRFAD
                     SLAHLRARGAAHFVEVGPDGVLTGLARTCLTTPEPLPATAPAPRTTPPPAPPATADAPE
                     AGAPAADAPAPLILPTLRGARPEAGALLDTVAALHAHGVPVDWRAVFTGRGARRTALPT
                     YAFQRRRYWLDADPPQQPALVPVPASASGPAPAGPPHSFLRSRTVTADDDGLLLGGLLS
                     PRDHPWLADHTVAGDVLLPGTAFVEMALYAGEQAGTPVVDELTLTAPLPLPPDGSVELQ
                     MKVAGADGVGRRALTVHARLHDAEAAPGPWRRHATATLVAAGDQPAQEPSVTPAADHPW
                     PPPGAVPLDLDGPPEARPPGGAYARLARAGLHYGPAFRGLRAAWRLGDEVYAEVTLPEA
                     AEAPAPGEGAAGFALHPALFDAALHTVALAGLPPAQDQPPGEDKAPPEDALDGGAAALP
                     FSFAGVRLYSCGARRLRVRMTPAAAAGRGETADAQPGRAVSGTEGGIGLELADETGAPV
                     ATIRRLFLRPLPRTGSGAVRTPAASLFRVDWTRSPQPLAASPVPTWGVLAGADAGPQDV
                     LAPASQDIPVYTDLAAAAAAAPEVVVAPCPGLPAADGDVEPAGQVHRTARWALALVQAW
                     LAEPRLAGSRLVVVTTHAVDSGTADSGTADTGAGISTAQAAVWGLIRSAQRENPGRFAL
                     IDLDGGPDSAAALPALLSGARPETAVRRGVAHVPEIVRVPGPAANAPLPVRRLDPEGTV
                     LVTGATGSLGMMAARHLVTAYGVRHLLLAARRGSDAPGMTELCSELADLGARVTVRACD
                     VADRRALAALLGEVPAEHPLTGVVHTAGVLDDGIVAALDDARLDRVLRPKADAALALHE
                     LTADRELALFVLFSSVAGVFGSAGQAGYAAANCVLDALARERRRLALPGTSIAWGPWRQ
                     SGGMMAHLTELDLRRMARAGFAPLTPDEGLALFDAAVRGADPAPVAARLDPSLAPGGSS
                     RRAVTPPAGTGPAAASGPSGAPAADPLVRRLAAATPGERGALLLAEVGALAAEVLGHTE
                     HDETIDPDDLLADWGLDSLAAVELRNRLATATDTVLPPTLLFDFPTPRAVATHLAQQYV
                     PHPTHPAPVAAASAAAEELPDSLAGLFRTACERGRTMEAMGLLTITARLRPVFDRAEAP
                     GAVPAAVPLASGGTGPHLLCFPALSALSGPQEYARLARGLAGLRPVTALPHPGFQRAER
                     LPATLDAFVTAQAAAVLAAADGEPFALLGRSAGGWAAQAVAQRLADEDAAPVAVVLLDT
                     YPAARADRDEALAPMTADMLRQAARFASHDPDRLTAMAGYFSLYSGWRPERPAAPTLFV
                     RAGEPLPGTAPAPAWPLPHTEITVPGDHFTLLEGHARSTARTVHDWLAELPHQ"
     aSDomain        20511..21452
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31760_CAL_domain.1"
                     /evalue="6.40E-97"
                     /label="IE248_RS31760_CAL_domain.1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="484"
                     /protein_start="170"
                     /score="316.7"
                     /specificity="Minowa: AHBA"
                     /tool="antismash"
                     /translation="RYEDLVGTEPRTPAPDDLGLDEVAWLLYTSGSSGTPKGVLLTQRN
                     RLAPVAAGLVGVLGMSRQDRLLWPLPLHHAMSHVVCVVGVAATGASAMIPPRFTVAEVL
                     AQLRRTDAPYTLLGGVPTTYSALLDEVRAEAARHPGQGDGDMGPGAGPGLGAPALHGCV
                     SGGASAGPAFRRSFEEVCGVPYLEHYGSTEAGPVTMAAPGDTTAAESCGRVLPGTRVRV
                     GGGADGQDVGEGELWVSGPGVTPGYHGSAQATAEVLRDGWFRTGDLARVDAGGELVITG
                     RASDLIIRGGANIHPSEVEAVLRHLPGVADAAV"
     aSModule        20511..21917
                     /complete
                     /domains="nrpspksdomains_IE248_RS31760_CAL_domain.1"
                     /domains="nrpspksdomains_IE248_RS31760_ACP.1"
                     /locus_tags="IE248_RS31760"
                     /monomer_pairings="AHBA -> AHBA"
                     /starter_module
                     /tool="antismash"
                     /type="cal"
     CDS_motif       20580..20636
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0001"
                     /evalue="1.80E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="IE248_RS31760"
                     /protein_end="212"
                     /protein_start="193"
                     /score="20.5"
                     /tool="antismash"
                     /translation="AWLLYTSGSSGTPKGVLLT"
     CDS_motif       21210..21281
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0002"
                     /evalue="1.50E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="IE248_RS31760"
                     /protein_end="427"
                     /protein_start="403"
                     /score="23.7"
                     /tool="antismash"
                     /translation="GELWVSGPGVTPGYHGSAQATAEV"
     aSDomain        21711..21917
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31760_ACP.1"
                     /evalue="1.60E-23"
                     /label="IE248_RS31760_ACP.1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="639"
                     /protein_start="570"
                     /score="74.8"
                     /tool="antismash"
                     /translation="LALVRRAVADVLGCAPGEVESGTALRDLGMDSLTATVLRERLSAA
                     TGLPLSEAVAFDFPTVAALAAHLG"
     aSDomain        22014..23285
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31760_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="8.80E-184"
                     /label="IE248_RS31760_PKS_KS.1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1095"
                     /protein_start="671"
                     /score="603.2"
                     /tool="antismash"
                     /translation="VVIVGMACRYPGGVSTPEELWRLVADGTDAIGPFPADRGWDTEGL
                     YDPDPGRPGRTYVREGGFLRGADRFDPGFFGISPREALAMDPQHRLLLEVAWEAFERAG
                     VDPRALRGSTTGVYAGLMYSDYAARFAVTPAQVEGYLGIGNAGSVASGRIAYTFGLEGP
                     AITVDTACSSSLVALHLAAQALRRGECALALAGGVTVMSSPASFVEFSRQRALSPDGRC
                     KAFGAGADGTGWAEGAGMLLLSRLSHARRTGLEVLAVVRGSAVNQDGASNGLTAPHGPA
                     QQRVIRQALADAGLAPADVDAVEAHGTGTRLGDVIEAEAFLAVYGRESRQRPLWLGSVK
                     SNIGHTQAASGVAGVIKTVQAMAHGVLPRTLHADEPNPAVDWPSGQVALLTRPEPWPEA
                     DRPRRAGVSSFGISGTNAHVVLEEP"
     aSModule        22014..28418
                     /complete
                     /domains="nrpspksdomains_IE248_RS31760_PKS_KS.1"
                     /domains="nrpspksdomains_IE248_RS31760_PKS_AT.1"
                     /domains="nrpspksdomains_IE248_RS31760_PKS_DH.1"
                     /domains="nrpspksdomains_IE248_RS31760_PKS_KR.1"
                     /domains="nrpspksdomains_IE248_RS31760_PKS_PP.1"
                     /domains="nrpspksdomains_IE248_RS31760_Thioesterase.1"
                     /final_module
                     /locus_tags="IE248_RS31760"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       22497..22544
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0003"
                     /evalue="1.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE248_RS31760"
                     /protein_end="848"
                     /protein_start="832"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GPAITVDTACSSSLVA"
     CDS_motif       22920..22964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0004"
                     /evalue="2.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE248_RS31760"
                     /protein_end="988"
                     /protein_start="973"
                     /score="10.6"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDVIE"
     CDS_motif       23022..23066
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0005"
                     /evalue="1.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1022"
                     /protein_start="1007"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAASG"
     CDS_motif       23610..23663
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0006"
                     /evalue="6.90E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1221"
                     /protein_start="1203"
                     /score="15.4"
                     /tool="antismash"
                     /translation="FLFTGQGSQRLGMGAQLY"
     aSDomain        23613..24485
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31760_PKS_AT.1"
                     /evalue="5.70E-102"
                     /label="IE248_RS31760_PKS_AT.1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1495"
                     /protein_start="1204"
                     /score="333.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQRLGMGAQLYGQRSLHPAFARSFDESCALFDPLLPRPL
                     RDVVFAHEDSEAGALLWTTRFAQPALFALETALFRLLESWDVRPDLVAGHSIGEVAAAH
                     AAGVLSLADACTLVAARGRLMDALPGGAMAAVAAGEDEVAAHLAQARGAVEIAAVNGPA
                     AVVVSGDEAAVRETVAYFRDRGRATAPLRVSHAFHSVHMEPMLAEFAEVVRGLSFTDPA
                     IALVTAVAGRAATDEELRAPEFWVDHVRRPVRFADSLAHLRARGAAHFVEVGPDGVLTG
                     LARTCLTTPE"
     CDS_motif       23871..23987
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0007"
                     /evalue="5.10E-20"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1329"
                     /protein_start="1290"
                     /score="63.7"
                     /tool="antismash"
                     /translation="VRPDLVAGHSIGEVAAAHAAGVLSLADACTLVAARGRLM"
     CDS_motif       24081..24119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0008"
                     /evalue="4.20E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1373"
                     /protein_start="1360"
                     /score="10.5"
                     /tool="antismash"
                     /translation="AAVNGPAAVVVSG"
     CDS_motif       24345..24377
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0009"
                     /evalue="9.20E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1459"
                     /protein_start="1448"
                     /score="9.7"
                     /tool="antismash"
                     /translation="WVDHVRRPVRF"
     aSDomain        24846..25388
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31760_PKS_DH.1"
                     /evalue="5.00E-51"
                     /label="IE248_RS31760_PKS_DH.1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1796"
                     /protein_start="1615"
                     /score="165.3"
                     /tool="antismash"
                     /translation="HSFLRSRTVTADDDGLLLGGLLSPRDHPWLADHTVAGDVLLPGTA
                     FVEMALYAGEQAGTPVVDELTLTAPLPLPPDGSVELQMKVAGADGVGRRALTVHARLHD
                     AEAAPGPWRRHATATLVAAGDQPAQEPSVTPAADHPWPPPGAVPLDLDGPPEARPPGGA
                     YARLARAGLHYGPAFRGL"
     CDS_motif       24930..25004
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0010"
                     /evalue="9.10E-12"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1668"
                     /protein_start="1643"
                     /score="37.3"
                     /tool="antismash"
                     /translation="WLADHTVAGDVLLPGTAFVEMALYA"
     CDS_motif       25356..25388
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0011"
                     /evalue="6.90E-03"
                     /label="PKSI-DH_m3"
                     /locus_tag="IE248_RS31760"
                     /protein_end="1796"
                     /protein_start="1785"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GLHYGPAFRGL"
     aSDomain        26499..27035
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31760_PKS_KR.1"
                     /evalue="1.40E-55"
                     /label="IE248_RS31760_PKS_KR.1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="2345"
                     /protein_start="2166"
                     /score="180.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGATGSLGMMAARHLVTAYGVRHLLLAARRGSDAPGMTEL
                     CSELADLGARVTVRACDVADRRALAALLGEVPAEHPLTGVVHTAGVLDDGIVAALDDAR
                     LDRVLRPKADAALALHELTADRELALFVLFSSVAGVFGSAGQAGYAAANCVLDALARER
                     RRLALPGTSIAWGPWR"
     CDS_motif       26502..26603
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0012"
                     /evalue="1.20E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="2201"
                     /protein_start="2167"
                     /score="17.9"
                     /tool="antismash"
                     /translation="TVLVTGATGSLGMMAARHLVTAYGVRHLLLAARR"
     CDS_motif       26880..26990
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0013"
                     /evalue="1.40E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE248_RS31760"
                     /protein_end="2330"
                     /protein_start="2293"
                     /score="59.4"
                     /tool="antismash"
                     /translation="LALFVLFSSVAGVFGSAGQAGYAAANCVLDALARERR"
     aSDomain        27306..27563
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31760_PKS_PP.1"
                     /evalue="9.20E-24"
                     /label="IE248_RS31760_PKS_PP.1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="2521"
                     /protein_start="2435"
                     /score="75.6"
                     /tool="antismash"
                     /translation="LAAATPGERGALLLAEVGALAAEVLGHTEHDETIDPDDLLADWGL
                     DSLAAVELRNRLATATDTVLPPTLLFDFPTPRAVATHLAQQ"
     aSDomain        27795..28418
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31760_Thioesterase.1"
                     /evalue="2.90E-29"
                     /label="IE248_RS31760_Thioesterase.1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="2806"
                     /protein_start="2598"
                     /score="95.1"
                     /tool="antismash"
                     /translation="HLLCFPALSALSGPQEYARLARGLAGLRPVTALPHPGFQRAERLP
                     ATLDAFVTAQAAAVLAAADGEPFALLGRSAGGWAAQAVAQRLADEDAAPVAVVLLDTYP
                     AARADRDEALAPMTADMLRQAARFASHDPDRLTAMAGYFSLYSGWRPERPAAPTLFVRA
                     GEPLPGTAPAPAWPLPHTEITVPGDHFTLLEGHARSTARTVHDWL"
     CDS_motif       27993..28055
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31760_0014"
                     /evalue="1.30E-04"
                     /label="NRPS-te1"
                     /locus_tag="IE248_RS31760"
                     /protein_end="2685"
                     /protein_start="2664"
                     /score="14.5"
                     /tool="antismash"
                     /translation="PFALLGRSAGGWAAQAVAQRL"
     gene            28647..29201
                     /locus_tag="IE248_RS31765"
                     /old_locus_tag="GCM10010336_64680"
     CDS             28647..29201
                     /EC_number="3.4.24.-"
                     /GO_component="GO:0031012 - extracellular matrix [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012630.5"
                     /locus_tag="IE248_RS31765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64680"
                     /product="matrixin family metalloprotease"
                     /protein_id="WP_190032467.1"
                     /transl_table=11
                     /translation="MKRLSAGLSAAAALLLTAPPPAAVAAAAPCVRGESESRLRSSVDD
                     GEIRWTANTAYADAYKHALKAWQYGGHKIRLAPDSATTVNDLEFTDYNDPQDHAAAKWN
                     YRSGPGQTDYIRFNTAAMKNASRTKRRQIAAHELGHALGLCHKSDAGGPGYVRSLMWPT
                     AHEYFDLPQDVDRANYSKLWG"
     misc_feature    28668..28670
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            29204..29752
                     /locus_tag="IE248_RS31770"
                     /old_locus_tag="GCM10010336_64690"
     CDS             29204..29752
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE248_RS31770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010336_64690"
                     /product="hypothetical protein"
                     /protein_id="WP_190032468.1"
                     /transl_table=11
                     /translation="MNVKTWAAAGTAAAVLLGGGWYSWERGSAPHTESLCGTPSGGTDA
                     EVATSAQGIAVVEAVGAAAHDPRAVGAENPELVTTPVRVVATMKGDFAPSIGVSQRVEP
                     GGAPGSFELATSNREVIMKPGERYVVAIGPGDLKARPGTTTFATFIQPARRGPAGEADY
                     WRNVIATAPPKPICDDTAG"
     misc_feature    29999..30013
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.47"
                     /tool="antismash"
     gene            30035..30367
                     /locus_tag="IE248_RS31775"
                     /old_locus_tag="GCM10010336_64700"
     CDS             30035..30367
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012752.5"
                     /locus_tag="IE248_RS31775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64700"
                     /product="ribosomal protein L7/L12"
                     /protein_id="WP_268254112.1"
                     /transl_table=11
                     /translation="MEEPGFRVLLREAGDRKMEAVRAVRTVTGLSLWNSKLLLDSAPVV
                     VTGPNWLEVADEAARLLEDAGARAAVLCDWCDRTITRGADPMDPAPCKGPWPAEACRAS
                     CPPASP"
     gene            complement(30559..31998)
                     /locus_tag="IE248_RS31780"
                     /old_locus_tag="GCM10010336_64710"
     CDS             complement(30559..31998)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546792.1"
                     /locus_tag="IE248_RS31780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64710"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_190032469.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 5.9e-28, bitscore:
                     91.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDTDTFGNGRPVLLRGGTVLPMDDPRRVLTNTDVLVQGDRITAI
                     GPDLAVPPGSAVIDASSGIVIPGMIDTHRHMWQTALRGYGADWTLSQYFVWFFIDHGKH
                     FRPQDIHAGNLLAAAEALDAGVTTTVDWSHGLATTDHAHAAVDALQAVPGRFVLAYGNL
                     HRPAAEWATDPAFRAFLDQRVPRDGMLDLQLAIDLGGDPSFPEKPAFEAARDLGVAVTT
                     HAGVWGTALDRSMTMLHQHGCMRPGTVYVHGSSLGDDSYRRIADTGGYLSISAESEQHA
                     GQGYPPTHAARAHGIPVSLSMDTSVWWSADLFSAMRATLAADRSREHAEGHARGESVTH
                     TTLRAHDVLSWATRGGAAALGRSHDLGTIEVGKKADLVLLKNDDSPVSFPLLNPHGHVV
                     LQAQRSDVHTVLVNGHVAKYRHRLRGIDLRALRDHVENTVEHLRGRLGESEWHKGMNPE
                     VPRAKTIEQSRFGTEQPPTGQ"
     misc_feature    32133..32150
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     misc_feature    32199..32214
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.54"
                     /tool="antismash"
     gene            32205..32900
                     /locus_tag="IE248_RS31785"
                     /old_locus_tag="GCM10010336_64720"
     CDS             32205..32900
                     /NRPS_PKS="Domain: PKS_KR (3-157). E-value: 2.3e-11. Score:
                     35.9. Matches aSDomain:
                     nrpspksdomains_IE248_RS31785_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056933.1"
                     /locus_tag="IE248_RS31785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64720"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_190032470.1"
                     /transl_table=11
                     /translation="MANIVIIGGTSGIGRELAGHLAGQGDSVVLTGRDAERARQVAREV
                     GKGRHHVRGIALDLAEPHEIARALSGTGPVDHLVITAVERDVNSVRDYSVDRAVRLATL
                     KVVGYTAAVAALREVLAPTASVVLFGGVAKDAPYPGSTTVTAVNGAVVSMVRTLSTELA
                     PVRVNAVHPGIVSDTPSWSGQADVLESVRLRTPTGRLATMADIVGATVFLMHNPAVNRV
                     NLTVDGGMV"
     misc_feature    32209..32223
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.75"
                     /tool="antismash"
     aSDomain        32214..32675
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS31785_PKS_KR.1"
                     /evalue="2.30E-11"
                     /label="IE248_RS31785_PKS_KR.1"
                     /locus_tag="IE248_RS31785"
                     /protein_end="157"
                     /protein_start="3"
                     /score="35.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="IVIIGGTSGIGRELAGHLAGQGDSVVLTGRDAERARQVAREVGKG
                     RHHVRGIALDLAEPHEIARALSGTGPVDHLVITAVERDVNSVRDYSVDRAVRLATLKVV
                     GYTAAVAALREVLAPTASVVLFGGVAKDAPYPGSTTVTAVNGAVVSMVRT"
     CDS_motif       32217..32303
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS31785_0001"
                     /evalue="2.10E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE248_RS31785"
                     /protein_end="33"
                     /protein_start="4"
                     /score="23.6"
                     /tool="antismash"
                     /translation="VIIGGTSGIGRELAGHLAGQGDSVVLTGR"
     misc_feature    32781..32783
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            33142..>33552
                     /locus_tag="IE248_RS37835"
                     /pseudo=""
     CDS             33142..>33552
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="IE248_RS37835"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRHVAARSLGGDVHRAEDIVQEAILRAWHHAPLLDRAGEGIRGW
                     LVTVVRNLAIDSHRARRARPYESGDLDVVEPASPGHEDRATDRLVVREALGELSEPHRQ
                     ILLYTRYLDKSVAETALALGIAPGTVKSRTHAA"
     gene            complement(33637..36762)
                     /locus_tag="IE248_RS31795"
                     /old_locus_tag="GCM10010336_64740"
     CDS             complement(33637..36762)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015607094.1"
                     /locus_tag="IE248_RS31795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64740"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_190032471.1"
                     /transl_table=11
                     /translation="MHFRLLGRLDVTASDGSPIALSGSLARAIVARLTLAGGRPVPRDA
                     LIDELWSERGARNPVNALQVQMTKLRTAFAERGEAGRLAMLAGGYRLALDDEDHVDVTV
                     FETSVRRGRERLRAGAHEEAEELLRSGLDLWRGRALEDLTGMVFEGERRRLDELRLTAL
                     EDAAHVGLERGRAQELISELTTLLADHPFREKLRGQLMLALYRSGRHAEALDLFHHGRV
                     LLDAELGLAPSPELRALQSAILEHDPALMTSNVVRSEAAERPPASARSGSGKTEGNLSR
                     SPGPYVGRRGALRALRETIIRERLVTLLGPGGVGKTRLALEALSRPDSPVEALWWIDLA
                     VTGEDGVLAALATTLGLSDASVATDQRPLDFLRRVVSSLENRTTIVAFDNCEHVLDAVA
                     PLVKTLLDACPQLTVVATSREPLGIAYEAHFTVEPMTAEEAGELFTLRAAKINPSFAAG
                     PDARQDVLTLCRRLDGLPLAVELAAAHVRMLSVAEIDRRLDDRFALLVKGERTAPARHR
                     TLRAVLDWSYALLGGAEQEVLSELALRVGGTALDDAERTGPPGPETTGTPTAGHGGGLL
                     PILTQLVDKSMLFTVPGAQGTRFQMLETVREYALARLRTEGRLQQAEERFVSWALDFAA
                     EHSAALHSREQSAHCLHIAEETANLRAGSELLVRQGRAAEALFLESSLGYFWYVSGREE
                     EGIDRLARTLDAYDSEPGTSDPERPPGPREEWALTYTFAWLAWLNHVAGRHESALGYEE
                     RYRAAWRQARNPDVAVIGPVYEALYARLTADEDRGDLFARAEAGIAGTAFQWDRAVLQY
                     NWSTYCLHNGDPDAAGEHALYGIEAARAADDPFALAICLTARGDAQESAGRREEARSLW
                     SEASEILRTMDARSRWAYRALRLAYLDIGEGDHDRADRRIAEVERIAAEVISYDLAYAG
                     ANLRAVVLAARSRFTEAAAALREVASAEAAPRHRRAVASLALTVCGDGGPADGERLADG
                     RREAAAIIEPLARDAVGLLLTEATERGSTEPGRRYALHERLARSPSVRAAFC"
     gene            complement(36945..37871)
                     /locus_tag="IE248_RS31800"
                     /old_locus_tag="GCM10010336_64750"
     CDS             complement(36945..37871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015607088.1"
                     /locus_tag="IE248_RS31800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64750"
                     /product="hypothetical protein"
                     /protein_id="WP_190032472.1"
                     /transl_table=11
                     /translation="MFRTARATSLAALSTAAILLLSACEGTDGSGGAAARASGDAGAAA
                     SPSAAAAGAAGLSLLSGTARQNGADPNSGDLAEAAAPAVAAAAKKPVARAWVQLSSGKA
                     GALDPVVLNGAGFTLYRFDKDTANPSKSNCSGACADTWPPYLVANGGKVFIDGIQPSAI
                     GFIPRDGALQVTIGGWPVYLFSKDTKPGDTNGQGVGGTWFGVTPDGKKAGQPGGTGTPP
                     VTSTTAPAAPARNATFFDSADFADPAEGITGPDCKPVRFSGSLRIGGAAKIWDGPNCTG
                     KSLLVQGDVRDLAAVGFPAVKSIRFLG"
     gene            38215..39639
                     /locus_tag="IE248_RS31805"
                     /old_locus_tag="GCM10010336_64760"
     CDS             38215..39639
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380454.1"
                     /locus_tag="IE248_RS31805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64760"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_190032473.1"
                     /transl_table=11
                     /translation="MSQESTHTLIQQAVEELEQLKANVSGRVCTPGDPHYAREVSAFNL
                     RSQIRPAFVVAAETPEDVQIAVRFAAAHGLAVGVLSTGHHAFPPQTSHGAVLITTRTMR
                     TVRIDAATASARVGAGALWSDVVGPAQRYGLAPLNGSSAGVGVVGYTLGGGLSPVLGRA
                     YGWAADHVRAIDVVTADGELRHVTEQSDPALFWGLRGGGSNLGIVTSLEFDLFPVTTFY
                     GGGIFHPAEHAEAVLHAYRQVVENAPDELTVSVALLNFPPIPEVPELLRGRFTVHVRVA
                     YLGSDTEAEALIAPLRAVGAPLADTVGRRGYDTFAEVHQDPTDPAPYEDRSVLLTELTP
                     EVVAAVLERVGPASGSVVTVLEIRHLAGALSREAGLPSAAGARDAAFMVWGATVGPPEV
                     VEAGTGDMNTLLKDLTPWSTGRLYQNFTSREAVASDVFAPDVLARLQRIKQQYDPRNVF
                     RAHNHNIAPTPGPAAR"
     gene            40197..40469
                     /locus_tag="IE248_RS31810"
     CDS             40197..40469
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE248_RS31810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_190032474.1"
                     /transl_table=11
                     /translation="MDTAARLLAQELADHTGPEAGEHAVLSITPERTDPPRVTVRMRRR
                     DAPRTPGEDLVHELLLTDREPVQELVQRLVLRLTAQDHGDPSGPR"
     gene            complement(40560..41003)
                     /locus_tag="IE248_RS31815"
                     /old_locus_tag="GCM10010336_64780"
     CDS             complement(40560..41003)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735010.1"
                     /locus_tag="IE248_RS31815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64780"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_190032475.1"
                     /transl_table=11
                     /translation="MSIATPSNTRTVVEELLRRIGEGNPERIAELYAEQGDWKLDWPEA
                     EHGRTATPWIRHRSTRADAAAHYRELAEYHVPEHVATEVERILVDGSDAVVLGEIRQTA
                     RPTGRAYKARFALHLTVTDGLVTRHHVYEDSLAVAQAFEAKDQ"
     gene            41528..41995
                     /locus_tag="IE248_RS31820"
                     /old_locus_tag="GCM10010336_64790"
     CDS             41528..41995
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677498.1"
                     /locus_tag="IE248_RS31820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64790"
                     /product="DUF2199 domain-containing protein"
                     /protein_id="WP_229895680.1"
                     /transl_table=11
                     /translation="MNYTAEAPFVWDPAFADADDCLLSSDQCVIQAEHYFVKGLIEIPV
                     IGSDEVFSWGAWVSLSRENFSRAADLWDTPGRESEEPYFGWLTTDLLVYSPTTLNLKTH
                     VHTRPIGQRPLIELEPTDHPLAVEQRTGITQDRVRDIAAAVLHPSRGERRK"
     misc_feature    complement(42032..42047)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            42143..43033
                     /locus_tag="IE248_RS31825"
                     /old_locus_tag="GCM10010336_64800"
     CDS             42143..43033
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389952.1"
                     /locus_tag="IE248_RS31825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64800"
                     /product="NmrA/HSCARG family protein"
                     /protein_id="WP_190032477.1"
                     /transl_table=11
                     /translation="MSDSRVIVVTGATGRQGGATARALLSRGWTVHALVRDPNKPEALA
                     LKEAGAVLVRGNLDDVASLDTALRGAYGVFSVQTFAGPDGFAGEIRQGKAVAEAAARAG
                     VAHFVYSSVDGADRPGQVRHFASKGEVERHIMTLGLPATILRPTFFITNFEHLGPQWVD
                     GELTLTMALAPDTKLQMITPGDIGSIAADAFDTPGDYLGRTVEIAADELTGPQLAEAFA
                     RAAARPVHFTSQPIEQVRAHSEELAAMFDWFNTVGFKADLATLRAQHPGLTSLEAWVDA
                     YWSAPAAPAAPALVA"
     gene            complement(43062..44060)
                     /locus_tag="IE248_RS31830"
                     /old_locus_tag="GCM10010336_64810"
     CDS             complement(43062..44060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735006.1"
                     /locus_tag="IE248_RS31830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64810"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_190032478.1"
                     /transl_table=11
                     /translation="MLPERAFRSAELAPADRFESWRALMSETHAPMEMRSEHAADFWVN
                     QRVISLGGIAVYPMECRPLTFQRTPKLIARSDPEAFHLSLIKRGAGAVTLGKDTVVHGV
                     SDIHTSDTSRPFEISSGPHCVEIIGVEVPKALLPLPPHIAGRVIGKRISAREGMGALVA
                     TFLDQVTKDSRSYREAEGPRLSGVLADLVASLFAGVLEADRSLTPETHRRALALRVMAF
                     IRDNADDPLLDVPAIAAAHHISVSYLHRVFQQEGDGVTVAAFLQGQRLARARQDLADPL
                     HQEVPVHVIGARRGFRHASAFSRAFREAYGVPPAAFRGQARAEDLAGADAF"
     gene            complement(44516..45457)
                     /locus_tag="IE248_RS31835"
                     /old_locus_tag="GCM10010336_64820"
     CDS             complement(44516..45457)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006608136.1"
                     /locus_tag="IE248_RS31835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64820"
                     /product="DUF4344 domain-containing metallopeptidase"
                     /protein_id="WP_229895672.1"
                     /transl_table=11
                     /translation="MLVLAGVVVTGCGGGVRDAGQGPGAGPRPQTARSGRVTVVYEAQT
                     VKPEDRQAVALIRKSRVLERTAEWVNRSLTLPHDMVVKVTAAVPPGVTDAVTQPDGRTI
                     FVPPSFLTAIEKALADVVKTVERPAPLPASEYNTDDLTVLSTEFIFGHEMGHALQRQLL
                     LANLGLEEDAADGFASFYTVNEVGPGPSLAAAVLFDELARKEGHPTLEGLASDHPVTQQ
                     RAFNFLCYLEGSDPKNYQKSLVDSGYLPKTRAPLCPQAWAMLDYGWWTQLQPHFSAAFR
                     DQGDAEQKKAHARLIAETEALARRIDEIRGSQ"
     misc_feature    45868..45882
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.93"
                     /tool="antismash"
     gene            46109..46762
                     /locus_tag="IE248_RS31840"
                     /old_locus_tag="GCM10010336_64830"
     CDS             46109..46762
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008734821.1"
                     /locus_tag="IE248_RS31840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64830"
                     /product="hypothetical protein"
                     /protein_id="WP_190032480.1"
                     /transl_table=11
                     /translation="MARPYSPGPKQFVFAVGDGNDQQVSVGDPQEAYVAFSAFFRDRES
                     DIYTIKDESSEQSLVLMPGQGVISRIKDADQLRSEHLRVDRGNRYLPSAMLFFENGYSG
                     LDRFGQWFSGLTDLDASPETRGAARAATFTTEAEAIEEVARIWATSGCVDPSDQYYVFF
                     DSHGVDDDRAERAELLKLIEFLGIERVDAPVNAAGGEVWVRTDTRLDVECARWS"
     gene            46836..48086
                     /locus_tag="IE248_RS31845"
                     /old_locus_tag="GCM10010336_64840"
     CDS             46836..48086
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964280.1"
                     /locus_tag="IE248_RS31845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_64840"
                     /product="DUF6357 family protein"
                     /protein_id="WP_190032481.1"
                     /transl_table=11
                     /translation="MREIVFTRNSGWIPNVIREDGELKLMLGAGADANHEPRTFTFSIS
                     EAHLAVIREDLARHLLLWSAVLPLCDDAGTRGRLDENAAVALLDPILLATPADADALFQ
                     RIRWDRSRLVSHGADIGLLERGQVCAAMRAATETSNGKRAQEYHAGRRRAERGAVLGPL
                     DAAILRYTGQYLHGATVPRRTPDAVAPELLPEVMRVIATAEQACAGMRIGRDPRRGNRA
                     TDRRDWDRMATTVEAAVRRSHPERVDEAVRTVSFLMCSEAADRSRRTPMEAAGHRADFG
                     GSARKTALSFTDDKGVEKKWLRDSPRTAAAEFWEFVGDRSAADNEVFTIEDEERGEGIQ
                     LHFYADSIARIMTLREGEGGSDPEYRVEYSLVDGIGGYRNLVSAFVRGGYAALEQHGPW
                     MSDVAEFERARRRREAR"
ORIGIN
        1 tcgcctcggc tggtgcccag caccgggtcc aggcgcagga gctgccagcg ctgccggacg
       61 agggtgcctc gtccctgagg ctggaaagtc cagctccatc gcacgatgcc gtcctcggca
      121 ccgccgacga cgaaggtgaa cgcggtgccg gggtcggcct gcgtgatctg ggagcgcgtg
      181 gtccactgct tgccgtccct gtggttgcgg ccgctgaacc aggcgccgac tcggggtcca
      241 tcgccctggt cgaaggcgac gtcagtggcg ttcgggctcc accggcggat cgcggacacg
      301 tcgctgacca ggtcgtatac ccgagtggag gcggcgtcga cccaggcgcg cctggtgaag
      361 gcgaaatccg ccgcgtccag ggtctcgaag gggtcgtgtt cgcgggttgc ggtactcaaa
      421 gcgtcctcct ggaccagtgc gggatggggg gtgaggccca cctcatcgcc gcgcgggtca
      481 gagagccaga cccgcggatg cctatccccg gcagggtgag gctgtgcgcc gcggctctcc
      541 ccatactcgg agccatgaac gggacatcac aactcgggga cttcctgcgg tcgcggcgct
      601 cccagctgcg gcccgacgag gccggggtac ccacctacgg ggagcgccgg cgcgtgccag
      661 gccttcgccg tgaggagctg gcgatgctgg cgggagtgag cgcctcctac tacgcccgcc
      721 tggagcaggg gcactcgctg ggcgcctcgc cggaggtact ggaggcgatc gcccaggccc
      781 ttcggctgga cgagtccgag cgccggcacc tgcacgacct ggcccgatcg gccaagcccc
      841 gcagccggcg gcgccccgcg ccagagctgg tgacagagcc caccgcccaa ctgttggacg
      901 cgctcgggga catccccgcg atcgtgatcg gccggcgtag tgacgtcctg gcgtggaacc
      961 gaatgggcca cgcgctgttc gccggacacc tcgaccccgg tgccccggag gtaccggcgg
     1021 agcgccccaa catggccagg ctggtgttcc tcgacgccca cacccgcgac ctgtacgcgg
     1081 actggccggg caaggccaag gcggtggtgg ggaatctgcg cctggtggcg ggccagtacc
     1141 cgcaggacag tgcactgcac acgctgctgg gtgagctgag cgcgaagagc gaggacttcg
     1201 cgtccatgtg ggccgaccac cgggtcaagg cctgcgcggt cgccgactac gagatgaggc
     1261 acccgctggt cggctcactg accgtcatgc agcagaccct gagccagggg ccgggccccg
     1321 gcatcgtggt cgccaccact gcggctggct caccctcgcg agccgccctg gatctcctcg
     1381 cccaggccgt cgcccgtacc gcccctgccc gtccggacag tcggctcagc accggctgac
     1441 ttccccacac caccccttcc tccggtcggc ccgtacccgc gtgtgcaggt acccggccgg
     1501 gcgtccctcc accctccacc ctcatgcgtc ggcgtgtcgc tgccgcatgc ccgaaagcag
     1561 taaaggatcc ccgtgttcac caagttctcc aaggccgctg tgtcagccgc cgtcctggcc
     1621 tccgccgcag tcgcgatggc caccgcggcc ccggcgtcag ccgtctccgc cccgctcaag
     1681 tgcgcgcgta ccgcagtgca cttcgacctg gccaagggcc agacaccgga gaacgtcacc
     1741 ctggctcccg acggcaccgc gtacgtcacc ctcgccaagg cccgccagat cgccgcggtc
     1801 tcccgcggtg gcagcgtacg gatcctggcc accctccccg aacccgccga cggcggcgtc
     1861 cacaccccgg ccctgggctt ccccctgacc accggcatcg tccgtgccca cgacggcacc
     1921 ctgtacttcc tctacgccac cggcaccgcg gacctgaccg gcgtatggcg cctgcgcccg
     1981 ggcggccgcc cgcagcgcat cgccgcactg cccgccaccg gcctgcccaa cggcctggcc
     2041 ctggaagccc gcacccacac cctgtacatc accgattccg tcctcggcac cgtctggcgc
     2101 gtgcccgcct ccggtggcac cgccaccacc tggtccaccg acccggcgct ggcacccacc
     2161 gggttcctcg gggccaacgg cctgaaaatc cacaacggag cgctttgggc aaccaacctc
     2221 gacaagggca ccgtcctgcg catcccgatc ctcgccgacg ggcgcgccgg caccgcccga
     2281 gtcaccgcca ccggcctacc cgggatcgac gacttcgcat tcaccggcca cggcgaccag
     2341 atcatcgccg ccctcaacac cgtcaaccag gtcgccctga tccagcccga cggcctccac
     2401 accaccgtcc tgaccgcggc cgacggcctc cagggcccga cctccatcgc gctacgcggc
     2461 gacaccgtcc acgtcatgag cgcggcctac ctcaccgcca aggaccccaa cctgatcctc
     2521 gcccacctgg gcggctgagt ctgccctggc tgccgcatgc ggcatggtca tcgcgttacc
     2581 cggccaggcg tcggccgccg agatcagctg catcgtcaac tccgtcgcgg tgtcggggtc
     2641 gacgatcagc ggcaccagcg gtgacgacac gatccgctgc tacgaaggcg tcgcccgcgg
     2701 cgtttccatc gaggccgggg ccgggaacga caccatcttc ggggaggcaa cggcggcccc
     2761 ggacgccctg gcggagtcgc cggcctgggc aacaacggga ccgtcaccgg caacatcacc
     2821 gccctcaact gcaccaccgg ccccaccctc ccctgaccca gccgcgcaca ccgccggtgg
     2881 cggcgcggat cacgggctca cctgacgggg acggcgtcct tcggggaggt gtgccagttg
     2941 gtgacgaccg ggcggtcgac cgtgatggtg ccgaccggca gggaaaccgg gtcggggtcg
     3001 ttgttgccga cggcgacgat gatgctgtcc agctccttgc cgccgttctc cttggtggtc
     3061 ttcgggttca ccccggcgta ggcggcggtg ctcccgctca gcttgatctg cttgccgacg
     3121 gactgctccg cggggcccgc ctcggtgccg tcggagccga acgcgacggt cggcagcgcg
     3181 gcgggcaggt agcaggtgat tccgggcttc gccttcgcgg tgatcaggat gtatccgccg
     3241 gcctggctct cggacttggt gctccacgcg atgtcgccgg cgccgcagac ctgcccgacc
     3301 ggcttctgcc cgctgttgcc ggtggcggcg ccggagccgg ccgcggttcc cttgcccgtc
     3361 gcgtcggcgc ccttggcgtt gccctgcttg ctcgccgggg ccggtgagcc ggacggggcg
     3421 cccgccttgc cggccggagc tgaggcggaa gagcccgggg cggcgccggt gtccgtggtc
     3481 gcgtccgagt cctggcacgc cgtcatcagc atggcgccac cgatgagggc tgccgagacg
     3541 agaaaggcct tgcgacggtt gccggacatg aaggatcccc ttggtggtca gtgggtgagg
     3601 ccgaactggt tcggttcctc ggcgcttgct tgatcactat gagggagccg agaccgagag
     3661 gaccccagtg ttctcgctcc acgacactgc tgtcacagac tggtgacatg atcacgaaac
     3721 atcggcggcc ggcgacggca gagcaggccg tccacgaagt gcggggcagc cggggctggg
     3781 gtccgtcagc ctgaggcggg gcaggagctg ggcggtgccg gactgccagt ggagccgctc
     3841 ggtcgccccg ctttccattt acgtctccgc gatcgagtaa ccgcccgaat gggcttctgc
     3901 tgtgcggact tgaggggagg gggctgtcag tgcccggggt cggcatgctc gcctgggtca
     3961 tgccccaggt cctccgtcac gggcaggcac tcggcgagca ggtcgacgac gtcgcgccag
     4021 gcccgctgcg cgtgccgtgg gtggtagccg acgccgggga ccacggggtg gtcgaccggc
     4081 gggtggtgga aggcgtgcaa ggcgccgccg tagaccgtga ggcgccagtc gacgcccgcg
     4141 gcctgcatct cagcggtgaa cgcgttccgt tgcgcgggcg gcatgatggg gtcttccgac
     4201 ccgaccccgg cccacaccgg gcagccaatg cgcgccgact cgcccggtcg gcccgtggta
     4261 gttgcgttga ccgtcccgat cgcgcgcagg ctgacgccgc cgcgcccgag ttccagcccg
     4321 acggcgcccc cggtgccgta gccgacggcg gcgatccggt cggggtcggt ccgcggttcg
     4381 gtgcgcaaca cgtcgagcgc cgcatggccg atgccccgca tccggtccgg atcggcgagc
     4441 agcggcaggc aacgggccag catctcctcg gggtcgccca gatagcgccc gccgtgaagg
     4501 tcgaaggcca gcgccacgta tcccagttcg gcgagagcat cggcccgttg gcgctcgacg
     4561 tcgctgagcc ccatgccctc gggtccgagg agcaccgcgg gccgacggtc gacgccggcc
     4621 gggagcgcga ggtgcccgat catcgtcaaa ccgtcggccg ggtactcgac cgtacgcgtc
     4681 gtaatcgtcg tcatgagact tgactgtagt gatcgtcgag cccggtacgg ccgctgttct
     4741 gccgctggca gaacagcgcg gcagcgctgt cggatcacct acgtgagcgg cgtctcatcg
     4801 gcggaagtgg gcgtgctgtt cgtgcaggaa ggcgtcgagg gtgcggggcc ggcggccgag
     4861 gatgtcggtg acggtcgtgg tgggagtttc gggtcgggcg atggcgagtt gctggatctc
     4921 cgtcacgtgc tgggcgagcc aggtgggcat acgggcgtgg tggatgaggt tggcgcgcag
     4981 ctcgtccggg gtgaggttga cgtagcggat ctggttgccg gtcagggtgg acagacgtga
     5041 agcgagttcg gggtaggcga cggcttcggg cccggtcagg gcgtaggtgc cgccggcgat
     5101 gtcgggcctg gtgagggcag cggcggcgac gtcgccgatg tcgcggcagt cgatgtagtt
     5161 gcagggcgcg tcgcccatcg tgccgacgat gacgccctgg gcgacggtgg gggccagacg
     5221 caggaggttc tgcatgaacg cgtaggggcg caagacggtg tgggtgaggc cgctggcgcg
     5281 caggtgttcc tcgacggcgt ggtgtccgcg ggagatggcg accggggagt cgggttcggc
     5341 ggcgggtgcg gagatcttga cgatgtgtcc gatgcccgtg tgggcggcga tgtcgatgac
     5401 gcgggtttcg agttcgacct gtgcggggct gttggccatg gcgaggaaga gctggccggc
     5461 gcccttgaag gcggtgcgca gcgagtgggg gtcggcggcg tcggcgtact ggacctcgac
     5521 gggcggttgg tgtgcgccgg ttgtgccggg gatcggcctg tgcggggtgc gggtcagtgc
     5581 gcggacgggt gtaccgagtg cgaggaggct gcggagcagg gcgttcccgg ttgctccggt
     5641 cgctcccatg acaacgatca tcgtgtgctc attccttggt gacttcccgg cggcgggtgc
     5701 taccggagat gggctcggtc gggcttgggc tcgtggggtg ggtaggcccg gtgccgggtg
     5761 ggctatgccg gggatgctgc ggcggtgctg cgccagcgca gggtgacgat ggtggtggcg
     5821 agggccgcgg agacgggcag gtcgatgcgc aggcgctcca gccacggggt ggcggggatc
     5881 ggggtgtggg cgggcagcca ttgggaggtg agccatccca gcagggctgc cgcgccgacg
     5941 gtggcgatga cgagtgccgc ggtcaggacg acgcgaggcg tggtggtggt ccaccgtcgg
     6001 ggccggccgc cgtgccgcag ccaggtgccg accaggaacg ccaccacggc ggaggtgccg
     6061 gcgatggagg tgcaggcggc cacggccaag tcccgctgcc cggtgacgac tccggcggta
     6121 ccggccatca gcgcgggggc ggcgtaggcg gtcagtacct cgcgccagag gatgaacggc
     6181 cgggaggatg cccggtttcg gctggttctg tccttcgttg cgggcatgtt ggcctctttc
     6241 tcgttcgtgt gagggaagcg aaggttgcgg tgggggcggc aggcttactc cgccaatgtg
     6301 attaggcagc taactattac ctcgtaaaaa gggccctgcc cggagggcgg ggccaagcag
     6361 gctgagagcc gggtcagtcg gcggtcagag ccgcgctgcc gcgcaccacg cgggcgagca
     6421 gatccaggaa caccgcgcgc tcctcgacgg agagcccgct caccatcgcc tccagccgcc
     6481 cgaaatgctc ggacgccatg tcgcgcagga gctgcgcacc gcgcgcggtc aggatggcca
     6541 cggtgccccg gccgtcctcc gtggacgggc ggcgggcgat caggcccgct cgctcaaggc
     6601 cgtccagcag gccggtgacc gtggccctgg agacgccgag gtcgagcgcg aggcgtgagg
     6661 gggatttctc cccgccgtgg tcttcgaggt cggcgagcag gcggtagcgc cccgtcgaca
     6721 agccgaactt ggcgaagtgc gcctcggccg cccggccgac cctcgcgccc gccgagatca
     6781 gccgcaccgc gaccagcacc gcctgcgggt cgacctccag gccgtagtgc tcgacctgcc
     6841 gtctggcctg gtccagcgtg ggtgcctcgc cgtcggtgtc atccctcgtc atgcacataa
     6901 tatggcggct aatcactttg gctgtcaagg cgcctcctcg gccgtggcgc cgacccggat
     6961 ccggcgggcc ggcctgctca aggggtgcgc cgcccgcgcc ggtcgaacca tttacataga
     7021 ctgtgaatat aaaaatgcta tggttctggc atgagtcgtc aagacaccgc cactggcgcg
     7081 tccgctgcca tcggggcagc cctctacggc ctggccacca gggccgcgag acgcctgccc
     7141 cgggacatga gcctgacgtc cgccgccacc ctggccaccc tggaccggac cggcccgcgg
     7201 cgcatcaccg atctggccgc ggtcgagggc gtcacccagc ccgcgatgac cgccctggtc
     7261 cgggtgttgg aggagtccgg cctggtcgag cggcagggcg acgcgtccga caagcgggtc
     7321 acgctggtgt gcctgaccga ggccggcgcc tcctatgtcc ggacgcggcg ccaggcgggc
     7381 gtccacgcgt tcgagcggtt gatcggcgag ctcaccggcg acgaggtcga cgcgctggtg
     7441 tcggcccttc ccgcgctgaa gcatctggcc gagctcgaaa gccaggaccg cgaggagccg
     7501 aagcggtgac cgggcggccg gtcggcgggg tcgcggtgga cgcgttcccg gcggcgcgct
     7561 ccgaggcgag gctgctggtc cccgccctga cgttcatcgc gctggtcgtg gcggcggtcg
     7621 ccagcctcgg gacgccgctc atcaccagcg cggcgacctc gttccacgtc tcgctcggca
     7681 gcgcgcagtg gacgctgacc atcgcactgc tcagcggcgc cgtcgccacg ccgctcctgg
     7741 gccggctcgg agcaggcccg caccggcggg ccacgatcct cgccaccctc gcggtcgtcg
     7801 tcgccggcag cgccctcacc gtgctcccgc tgccgttcgc gtggctgctg gccggcaggg
     7861 cggcccaagg cgtcgggctc gggctgacgg cgctgatgat gggcgtggcc cgggaccacc
     7921 tccccgagga gcgcggcgcg gccgtgatcg ccctgatctc ggtggtctcg atcatagggg
     7981 ccggcgtcgg ctacccgctg gccgcactgc tggccgagct cggcggggta cgggccgcct
     8041 acggcctcgg cctcgtcgtc accgccgccg ccctcctgac cgcgtggcgc ttcatgcccg
     8101 aagcccccga aggccgctcc acccacgtgg acgtggcagg cgcggtcgtc ctggccgccg
     8161 cgctgctcct ggtgctgttc ctcgccggcg aacggaacct gtggagccgg cacctcgccg
     8221 tggcggcggg cctcgccgtc gtcgcgctgg tgctgctctg cgtctgggcc gtcatcgagc
     8281 tgcgcagcac gacgcccctg gtcgatgtgc gggcggtgcg gcacccggcg gtcgccgggg
     8341 cgaacctcgc catgttcgtc ggcgggatcg gcatgtacct cctgctcacg ctcatcaccc
     8401 gctacgcgca gacgccgcac ggcgccggct acggcttcgg gctgacgacc ttcgtcgccg
     8461 ggctggtcct catcccgttc tcggtgctgg ggttcgtcgc cggcaagctc acaccgcgga
     8521 tccggacgcg gatcgccgac cccctgctcc tggccggcag cgccgtcgtg gtcggcggcg
     8581 ggttcgccct gttcgcggcg gcccggtcgg acctggccga actgttcgcg gcgatgggcg
     8641 tactcggctt cggcgtcgga ggcttctcgg ccgccatgcc cggcgtcatc ctggccgtca
     8701 cccccaagag cgagacgtcg agcgccatga gcttcaacta cgtcgtccgc agcgtcgggt
     8761 actccctggg cagcgccatc ggcggcctga tcctcaccgc gggtaccggc cccggccacc
     8821 tcttccccga cgacagcgcc tacaccaccg cggcgctggt cggcatcggc gccatggcga
     8881 tcacgacgct gacaagcctc gctctcgccc gccgacgctc gtccgagacc aacccgtaag
     8941 tcagatgcac tcatccccac actggaggtt ccatgcccaa gggctactgg gtcagcgcct
     9001 accgcaccat ttcagaccct gagaagctgg ctgcctacaa caagctggcc cctgcggccg
     9061 tcaaggccgg gggcggccgg gtcctcgccc gtgacggtcg gatcgtggcg catgaagccg
     9121 gaatcgccga gcgcaccatc ctgatcgagt tcgacagctt cgaacaggcc gtcgcggcgc
     9181 acgagagcgc ggcctaccag gaggcgctgg ccgccctctc cgacggcgtc gagcgcgact
     9241 tccgcatcat cgaaggcacc gactgaccga ggctcagccg gatcttcacc gaagcagcag
     9301 gattccgggg cacaccggcc cgcttccgtg aagggcgtca ccagctggtt ccctcacggc
     9361 tcacacaagg gggcgggccc ggaggtctct ccgggcccgc ccccttgtac gtacgccggc
     9421 ccttcacctg cacagcgggc ggttcagttg ttgacgaacg tgaggctggt cgcgtcgtag
     9481 cgggtgcccg cgatctgctc ggacggcgcg gcggcctcga tggcggccaa gtccccgggg
     9541 gacagctcga cggccagggc cgcgaggttc tcctccaggt actgccggcg ccgggtgccg
     9601 gggatcggca ccacgtcgtc gccccggtgc tgcacccagg ccagggcgag ctggccggtg
     9661 gtgacgccct tggccgcggc cagctcgtcg atccgcgcga cgatcgccag gttccgttcg
     9721 aggttgccgt cggcgaagcg cggctggctg cgccgtacgt cggtctcggc cagcccgtcg
     9781 accgagctgt accggccggt gaggaagccg cgtccgagcg gggagaacgg gaccaggccg
     9841 atgccgagct cgcggcagac cggggcgatc tcggcctcca gatcgcgggt ccacagcgac
     9901 cactcgctct gcagcgctgt gatcgggtgc accgcgtgtg cccgccggat ggtgctcgcg
     9961 ccggcctcgg agagcccgag gtggcggacc ttcccggcct gtaccagttc ggccatggcg
    10021 ccgacggtct cctcgatggg gacctgcgga tcgacgcggt gctggtagta gaggtcgatg
    10081 tggtcgacgc cgagccggcg caacgacgcc tcgcaggcct gccgtacgta ggcggcgtcg
    10141 ccgcggacca gggtgggctc gccgaggcgg ttggcgaagc cgaacttggt ggccagcacc
    10201 acctcgtcgc ggcgcccggc gacagcccgc ccgatcagct cctcgttgtg cccggcgccg
    10261 tagaagtcgg cggtgtcgag gagggtcacc ccgcggtcga gggcgtggtg cagggtcgcg
    10321 atcgactgcg cgtcgtcgct ggcgccgtag ccgtggctca tgcccatgca ccccaggccc
    10381 tgagcggaaa ccgccaggct gccgaggtgc cgggtgggga cgttggtggt catgccgttg
    10441 cctccttgtg ccgagatcat ctgtccagga cgctaggtgt tggagcgcac tccatgtcaa
    10501 ctggctcctg ctgccctgga gaagggccca ctccgcctcg gacggtgccg ttgagcgggg
    10561 aaccctcgac gtagctgtag cggctggccc gcagacccga ttgcgtcggg tcgagtcgcc
    10621 gggtatcacg gctctcgtag tgggtcgctg gtcgggtgcg gtcccggcac cgacgtcacc
    10681 gcacccaccc cggcgtcctg gccccaccgg tggactgatc gccccgcagt cgtggaagat
    10741 ccgcgtccgc acccgcgtcg agtacggcat cgcacacgtc aggaaccggc gggtactcgc
    10801 tcgccaccac agccgacgtg agcacctgag cgacaccacc cgcggtgccg accagccaga
    10861 gtgaccgccg ggccgacccg cacctttccg tttcgcacgt caaggcccct tacaacagga
    10921 cccccagggc gaaccccagc cctatcgcca cgaacaacgc gcccattgcg ctgaacagcc
    10981 accagaaggc ggtgccttcg gccgggaggg tccagcgtga cgggtctgcc tggtcgtacc
    11041 ggacctcgac gcgggtaccg acgggaaggg tcctgtcctt gggccgagcg atgctcgtcc
    11101 tggtttccat tgcgcggccg tcgcccgtgc tccaagcgat gaccgggtag tacacggtgg
    11161 ttccgacgct ccggctggtg ctgccggaat ccgaggccgg cgcgatccgg gtctcctcaa
    11221 gacgggtcac cacaccccgc gcggtactgc cctccctcag caggaaccgg acgcgtcgga
    11281 tcttgaggga ggcgacgacg ccgatgaccg accccgcggt ggtgaacacc gatgcgagga
    11341 gcaggaggat ctgggaagca gacacagggg tcgtctcgat tctggagccg aagaactcct
    11401 gacagcatgc cagtgcggcg atctccccat acggcagggg catggccggg gcgggcctca
    11461 acgcagcccc gccgacggtc tcctcccgga ggaggaggcc ggaccgggcc gcaggtcccg
    11521 ggcccggggg cggacgggac cggggtcctc gtgcccttgg gcgatgtgcc gtaccagggc
    11581 gggttcctag cctcggggca tgcgatcaca cgaagcggac gatgctcaag gagaccccgt
    11641 gaccacggtc agccccgccg cacgccgcgc cttggccgtg ggcctcgccc tcgccgcctg
    11701 cctcacgtct tcccccgtcc tggccacggc cgccgaggcc cccgcccagg acagcgccgg
    11761 ggccggactg gaccggtact accgccagca cctcggctgg ggcagctgca tcaagggccc
    11821 cgacgacacc acgggccgcg atctggacca ggcgggcgtg cagtgcgcgg aggtgaccgt
    11881 gcccctggac tacgccgacc cccgggggcg cacgatcacc gtggcgatct cccggctcaa
    11941 agccaccgac acccgccacc gcatcggcgc gatcctcctc aacaacggcg gtccgggagg
    12001 tcccgcgctc cagtccccgc cgcaggcccg cgcgtcgatg aaggaggtcg gctcgcgcta
    12061 cgacatcgtc ggcttcgacc cgcgtttcat cgggcgcagc accgcgctgg actgcggctt
    12121 gcccgtcggc atgacctggc tgtccgccgg cgccggccgg gcgggcttcg accgccaggt
    12181 cgccctgcag aagagcctgg ccgacaagtg ccgggccacc gatgccgcgg tgctcccgca
    12241 catcaccacc cgcaacacgg cccgcgacat ggacgtcatc cgcgcctcgc tcggcgagcg
    12301 gaagatctcc ttcctgggct actcgtacgg cacctacctg ggcacggtct acacgcagat
    12361 gttccccggc cgccacgacc ggatggtgct ggacggggcg atcaacccga gcgactaccg
    12421 cccccggctg ctgaagggca ccgagcgcga gaacgagaag gcgctgtccg actgggccgc
    12481 ctgggccgcg gagcaccacg acacctacgg cctcggccgc agccgcgccg gagtgctcgc
    12541 cgccgtcgac cgcatcgtcg cggcggccgc gcgcgctccg ctgaccatcg gcgccggcgc
    12601 cgatgccttc cggatagacg acagccaggt gccgctcctc ctcttctcgg gcatcgcgga
    12661 cgacaccgcc ccggcgcggg cgtcgttcgg cgagctgctt tccgtactgg ccaaagccgc
    12721 ggagggccgg ccgacgacgg tgccgccgat gctggtcccg gagctgcggt acgtgctgcg
    12781 cggtgagggc gagcccaccg gcgcgcagtc cgccgtcatc tgcggggacg tggccgccgc
    12841 gcgcgatccc gagctctact ggcgggacat cgagcgcaac cgcaccgcgc acccgctgtt
    12901 cggtgctctg accaacaaca tcaacccgtg cgccttctgg gactcgccgc gcgaagagcc
    12961 cacccgggtg cggcgcgatg cccctgcact gatcgtcgcc gccaccggtg acccgcgtac
    13021 gacgtacaag ggaagcgtcg agctgcacga gcagctgccg agctccaggc tggtcaccct
    13081 tgagggcgcc aaccggcacg cccttttcgg gcgctacggc aacgcgtgcg tggacgacca
    13141 ggtcaaccgg tacctggcca ccggcaagct gccggtgagg gaccggactt gcgtcaagca
    13201 ggcggggtag cggcccgcgg aggccggcgc ctgggccggg gcgtagtcag aacgtcagcc
    13261 ggaacagtgc gcccccgccc ggggcggcct ccgccgtgag ctccgcggag tgcgcccgcg
    13321 cgatctgccg ggccatggcc aggccgagcc cggatcccgg cagggcgcgg gccgccccgg
    13381 cccggtagaa ccggtcgaag acgtgcggca ggtcctccgg cgcgattccc ggcccgtggt
    13441 cacggaccga cagctccggt ccccggccct ggccgcccgc taccaggtcg acctcgacgg
    13501 gcagtccgtc cctgctgaac ttggccgcgt tgtcgagcag gttccccagc aggcggctga
    13561 ggcgcgcggg caccccgggc accacgacgg gctcggccgg tgcccgtagg tggaagggca
    13621 cggccggcca atgcgcccga gcgctctgca cgcagtgctc caccagcgcg cccagcgaga
    13681 cctcttccac cagcggctgc ggctcctcgt cgcgtgccag ctcgatcaga tcgttgacga
    13741 gccccgtcac ctcccgcagc tgccggccca gcgcggccga ggcgcgctcg cgctgttcgg
    13801 gcgtgagccg gtcggcccgg gccagcagtt cggcgttggt ccgcagtgcg gtcagggggg
    13861 tgcgcagttc atgggaggcg tccgcgacca gttggcgttg tgcggccacc gactgctcca
    13921 gctcgcccag catggtgttg aagctcgtgg ccagccgggt gatctcgtcc tcccgccccg
    13981 gtggcggcag ttcgatgcgg tgccgtgcgt cacgagtggc ggcgatccgc tcggccgtcg
    14041 cggtgaggcg ggcgaccggg gccaggccgg tccgtgaaac ccagtggccg agaagggcgg
    14101 ccagcagtac gccgaccacc gccgtcagca ccagccagcg ggcggcctcc tcgatgccgt
    14161 cttcgaccgt gtcggcccgc agggccacct gcagcgcgcg ccccttggcg tagtcggtgg
    14221 tgagcatccg ggcgggatac ccggccaccg tgatgttggt gtagtagggg gcccgcttcc
    14281 cctcggcgac ctcccgcgcg gccggggcca cgggcagccg ccccggctcc gtgggtttct
    14341 tggcggggtc ggcggacacg acctccgcac acgcgggtgc ggccaggaac cggcattccc
    14401 ctgccaggac acccggcccg gcccccggtt cgcgctgggc ggcgagccgc gcggactgcg
    14461 tgagggtgag gtcgagctgc tcgtagagcg cggccctgac caccaggaac gccgccgcgc
    14521 acaccccgag cgccaccagg gccacggcgg ccgtgaccga catcgccagc cggacccgca
    14581 gggggccgcg ccggcgccag acccggccga gccgccggcg gccgccgctc acgccgcgtc
    14641 cagccggtag ccgactccgt gcacggtgtg caccagccgg ggctcgccgc cggcctccag
    14701 cttccggcgc aggtagccga tgtagacggc gagggagttg gagtccggcc cgaagtcctg
    14761 tccccacacc agttcgagga tcagctcgcg ggggagtacc tggccggcgt gacgcacgag
    14821 gagttcgagc agggccgctt cggtacggct gaactccagc gggcggctcc cgcggcgccc
    14881 ggtccgggtc gccgggtcga gcacgaggtc ggcgacgccg agcgcggcgg cgccgccggg
    14941 tgcgggcgac gcccgccgca gcagcgcgcg tacccgcgcg accagctcgt ccagggcgaa
    15001 cggcttgacg aggtagtcgt cggcgcccgc ctccaggccg tcgacgcgct cgctgacgga
    15061 gtcgagcgcg gtcaggacga ggatgggcgt acggtcgccc atcgcgcgca gctgccggca
    15121 gacgccgagg ccgtcgagga cgggcatcat gacgtcgagg acgaccgcgt ccggctccca
    15181 ggccgccacc tgggagaggc ccgcgagtcc gtccgccgcg ccccgcacct cgtacccctc
    15241 gaccgcgagt ccgtcctcga cggctgcccg cacctccggc tcgtcgtcga cgacgaggat
    15301 gcgctgcccg cccgcactgc ctgtactgcc cgtggtgtcc tgggaactca tggggcaaag
    15361 actgccaaag gcatctgaga aaacctctta gaacgttctt agggcgcacc gggagtgtgc
    15421 gcacatgacc accaccacac cacacacacc tacgacactg tccgtcgtga tcggtgcggg
    15481 cggcaccggc gggcacatct accccggcct cgccctcgcc gaggcgctgc gtgccgccgt
    15541 gcccggagcc gtggtctcgt tcatcgggac cgagcggggc ctggagaccg agctgatccc
    15601 cggcgcaggc taccgcctgc acaccgttga catgatcccc ttcgatccct ccctgggtgc
    15661 gaagcggtac ctgctgcccg cggcgctgct gcgctcggcg caccaggcgc gctcggtgat
    15721 ccgggcgcag ggtgcccacg ccgtcgtggg catgggcgga tacccgagcg cccccgccgt
    15781 cctcggcgcc cggctcgcgg gcctgccggc cgtgatccac gagtccaatg ccgtgcccgg
    15841 ccgtgccaac cagttcgcgg cccggctcac cccgcacgtc gccgtcgcct tcgaccgcag
    15901 ccgcgcccac ctctccggcg gtgagcgggc gctgaccacc gggatgccga tctccgccgc
    15961 cctgtccggc ctcgcggagc tgcccggagc ggaccgggtg gcgctgcgcg ccgaggcccg
    16021 gtacgcgctc ggggttcccc cggggcgccg gctgatcgtg ttcaacggcg gcagcctggg
    16081 cgccgtccgc ctcacccggg cggccgccgc gctggccggc ctgtggcagt accgggacga
    16141 cgtacagctc ctgatcaaga ccggaccggc cgaactgccg gacacggtga ccgaactcgc
    16201 cacgtccggc ggccagcgca tcgcgcgggc cgtgccgtac ctggaccgca tggacctcgt
    16261 ctacgcggcc gccgacctgg tggtgtgccg cgcgggctcc gcgaccatcg ccgaactggc
    16321 ggcgaccggc gtcccggcgg tactggtgcc ctacccgtac gcccccggcg accaccagac
    16381 gcacaacgcg cgggtcctgt ccgacgcggg cgccggagta ctgctgcccg acgcggagac
    16441 caccgccgag cgcctcgccc acctcatcgg gccgctgctg gccgacccgg cccggctgtc
    16501 ggcgatggcc ggcgccgccg accccggccc gcacgcgcga gccgccgaac tgctggccgc
    16561 cgaagtactc cgcgtcgccg gtttcgtccc cacccctcac ctggagcgca tatgaacagc
    16621 tggaccgacc gcaccgtcct cgtcaccggc gcggagggct tcatcggctc gacgctggtg
    16681 gacctgctgg tgtcacgggg cgcgcgggtg cgtgccttcg tccactacaa gccgtacgcc
    16741 gagaagggcc acctggcgcg ctacctggcc gacccggacg gcccggtgga gatgtggacg
    16801 ggcgacgtcc gtgacgcggg ccgggtcagc gacgcggtgg ccggctgcga caccgtcttc
    16861 cacctggcgg ctctcatcgg gattccttac agctacgcct cgcccggcgc gtacgtgcag
    16921 acgaacgtca cgggcacgca gaacgtggcg gaggcctgcc ggcggcacgg cgttcggcgc
    16981 ctggtgcaca cctcgaccag cgaggtctac gggacggcgc tgaccgcccc gatctccgag
    17041 agtcacccgc tgcagccgca gtccccgtac tccgcgtcga agatcggcgc ggacatgatg
    17101 gcactctcct tccaccacgc cttcgaactc ccggtgacgg tggtacgccc cttcaacacc
    17161 tacgggccgc gccagtcggc gcgcgcggtc atcccgacca tcctggccca actgcacgcc
    17221 ggctcgcggg agatccgcct cggctcgctc acgccgaccc gggacttcac gtacgtcacc
    17281 gacacggcgg agggcttcct cgcggtggcg gagtgcgacc gggcgctggg ggaggtggtc
    17341 aacctcggca ccggtgagga gatctccgtc ggcgccctgg ccgaggccct gatcgcggcc
    17401 tccggccgtg aagcgaaggt ggtcgtggac ccgacccggc tgcgcccctc gggcagcgag
    17461 gtccagcgcc tgctgtcgga caactcgcgg gcccgggagt gggccggctg gcgcccccgg
    17521 gtcggcctgg aggaggggtt gcgccacacc tcggcctgga tcgcggcgaa ccagtccctc
    17581 ttcgcgccgg accggtacgc ggtctagcga ggcgacgccc cgcccgggtg gcagaccccc
    17641 gcggcctgca ccggctggtc ccgtgcgagc accgcagcgg ggagcccggc cggtcccgcg
    17701 gcgggtaggc cggacctcca ggccggggcg gcgccgcctg cggttcctcg gtggcggtgg
    17761 tcagcgggac gcgggcgctt ccccagggcc gctcggggtg gtccgcgggg tcgagccgtc
    17821 cggcagcccg ctcaggtcac caggcgcagc gacgttccgg cgatgcccag ccgtacgctc
    17881 tgaccccagg tcagctccag ggcgtcgccc tccatcccgt cgccgaacac tacgatccgg
    17941 tccgactcca cggtcagccg aagcccctgg ccctgcccca gctcaccggc gacccttgtc
    18001 gttccggtcg ccggagaggg ccaggcctcc cgcacgaacc acaggagccg ccgctcgcag
    18061 ggtgagggca gccccgcgga gctgccgcgc tccagccaca gggaacgcag ccagccggtg
    18121 gcgcccgtac cggtgcccac cagcaccccg gaggacgcct gggcctcctc cgggccctgg
    18181 tcgccctcgc cgcccaggcg gtagcgggcc gtctggtgac cgggcgagcc caggtagatc
    18241 tcgttcaggg cgagaaggcg ctgggtgtcg tcggcgacgg cctcgaccat ggtcagctcc
    18301 tccgcccggc tcccggcggc gatggcggca cgcagcaacg cggccgtgtc ggcgcagcgg
    18361 tgacggacca ggacccccgg gttccgtccc gggtcggtgt cgatgcccac gaccggctgt
    18421 ccgcgcaggt acttggcggt gttggcgacc aggccgtcct ggccgaccac gaccaccacg
    18481 tcctccgggg cgaacgggaa gcggtccagg tccgcccgct ccacgctgga gctgcgccag
    18541 gtgagcggca ccgccgccgc cacctcgcgc agtgcctgcc gcgtgcgttc gtggcggtgg
    18601 accacctcgt cgatcgaccg gccccggcgg gacaggagga acgcggcctg cccgtgcgtg
    18661 ccgtaccggg cgagcagttc ctcgtactcg gtcctgcggt gcacgagcac cgcccgcggg
    18721 gccaggctca cgcgtccgcg ccgccttccg gacgtccgag ccgggcgagg agcccggtga
    18781 ggacgtcagg agacagagtg atgctgtcga tccgcggcag gttctccgcc agccgggtcg
    18841 ccgccagggc gtgcagcgtc ctcgggccgg cctcgtcgtg cacccgcagc caggcggcct
    18901 gagcctctgc gcgcgccgcg cccgtctcgc gcgccgcctc ggcgtccgcg cgggccaggc
    18961 ggaccttgcg ggccgcttcg gtctcggtcc ggatgccgtc cgccgccgcc ttctcctcgg
    19021 cctcgcggcg ggcgttggtg ccgcgctggt cgatcaactg ctcctcgcgc cgggcgagtt
    19081 cgatctggct ggccagctcg ttctcggcga tggcgcgctc gcgctcgacg gcgacggccc
    19141 gccgttcgta ggtggcccgg tccgcctcct gctggatctg ctcgcgggcc ggggtgcgca
    19201 gggcgcgctc cacttcggcc tcggggcgga tcgccacgac ccgtacggcc accacgtcta
    19261 tgccggtggc cgggagcctg ggctcggcgg cgagaccggc ggtgacgctc ccccgtacgg
    19321 atgcgacgcc gtcaaccagg gcgacggcca gcggggtccg ggccagtacg tccagcgtgt
    19381 gctgctgcgc ggtctcggtg aggagagtgg cgatctgctc caagggggct ccgcgccagc
    19441 tcccggtgtc cgggtctacg gagaagtcga gccgggccgc ggcttcggcc gggtcgctga
    19501 tccggtaggt gacggaggcc tgcacggaga cgtcctggaa gtcggacgtg cgcgcgtgga
    19561 acgccatggc cagctcccgg tcttcgaccg gtacttcgga cagtgccgcc gagagcgacc
    19621 ggtaccagaa actgagcccc ggcccgtcgt ggacgagctg gccgcgcttg tggtggcgga
    19681 tgtgcgcggt gggcgcggat cgcagatggc gccagccgaa gcgccgggtg atgtcggcca
    19741 tggcgaaccc ccttcatttc gtcagcgcga cgataacgag aagtgttcat atcgtcaaga
    19801 ggacgaaaag acggctgtcg gggctctgcc cggcagatcc ggctgtcgcg cgctccggcc
    19861 gcgcgcggcg gcacggcctc aagcccctcg ccgtctgccc ggcctgccga ggagccgggc
    19921 cgctgacgca acccttcggg ccgtgcggac atcctcaacc acgagtccac acaggaggtt
    19981 tcgcacaggt gagtgttcag gtgggtacag acgcggacat cgtcaggcca ctcccggtgc
    20041 tgctgcggga gcatgcccgg agcatcgggg agcaggtcgc cttcgaggac cgccgtaccc
    20101 ggctgaccta ccgggacctg gaacgcagaa ctcggcgcct ggcgggtcat ctcgcggggc
    20161 tgagcccggc gcgcggggag cgggtggcga tcctgctcgg caaccgcgtc gaggccgtcg
    20221 agagcctgct ggccgtcacc cgggcgagcg cggtgggcgt gccgctggat cccggcggct
    20281 ccgggccgga gctggcccac ctgctggacg acagcggagc ccgtgtgatc gtcaccgatc
    20341 ccgcccggct gtcccggctg cgcccgctct tggcggcgcg ccccgggctg acggtgctgg
    20401 tggtcgagga ggccgaggag atcgaggagg tggaggaacc gccgggcgcc gacccggacg
    20461 gggagccgga cgggcacccg cagccgggga gcgcggaaac cgtccagctg cgctacgagg
    20521 acctggtggg cacggaaccg cgcacgcccg ccccggacga cctcgggctg gacgaggtgg
    20581 cctggctgct ctacacctcc ggctcctccg gcacccccaa gggcgtgctg ctcacccagc
    20641 gcaaccgcct cgcgccggtg gccgccggtc tcgtcggcgt cctcgggatg tcccggcagg
    20701 accggctgct gtggccgctg ccgctgcacc acgccatgag ccacgtggtc tgcgtggtgg
    20761 gggtggccgc caccggggcg agcgccatga tcccgccccg cttcacggtg gcggaggtgc
    20821 tcgcccaact gcgccgtacg gacgccccgt acaccctcct cggcggggtg ccgaccacgt
    20881 actccgccct gctcgacgag gtacgcgccg aagcggctcg ccaccctggc caaggcgacg
    20941 gcgacatggg cccgggcgct ggcccgggtc tgggcgcgcc ggccctgcac gggtgcgtca
    21001 gcggcggcgc ctcggccggg cccgcgttcc gccggtcgtt cgaggaggtc tgcggcgtcc
    21061 cctacctgga gcactacggc agcactgagg cgggcccggt caccatggcc gcgccgggcg
    21121 acaccacggc ggccgagtcg tgcggccggg tcctgcccgg cacccgggtc cgggtcggcg
    21181 gcggagcgga tggacaggac gtgggcgagg gcgagttgtg ggtgagcggg cccggcgtga
    21241 cgcccgggta ccacggcagc gcgcaggcca ccgccgaggt gctgcgcgac ggctggttcc
    21301 gcaccggcga cctggcccgg gtcgacgccg gcggggaact cgtgatcaca ggccgggcca
    21361 gtgatctgat catccgcggc ggggcgaaca tccacccctc ggaagtggag gcggtgctgc
    21421 ggcacctgcc cggggtggcg gacgccgccg tggccggccg cccgcacccc gccttcggcg
    21481 aagtaccggt cggctatctg gtccccgagc gcggccgggt actcgaccgc gccgccctcc
    21541 tcgccgcctg ccgccgggaa ctctccctct tcaaggtgcc cgccgccctg tacgaggtgg
    21601 agggcatccc ccgtaccgcc tccggaaagg tacggcggca cgcgctcgcc gacctgcccg
    21661 gacggctgct ggacggcacg gcgccggccg cggaagcggg ggcggacgta ctggccctgg
    21721 tacggcgcgc cgtggcggac gtactgggct gcgcgcccgg ggaagtggag tccgggaccg
    21781 cgctgcggga cctgggcatg gactcgctga cggctacggt gctgcgcgag cggctgtccg
    21841 cggcgaccgg cctcccgctc tccgaggccg tcgccttcga cttcccgacg gtcgccgcgc
    21901 tcgccgccca cctcggcacg ctgggcgccg ccgggccggc gccactggaa cctggcccgg
    21961 acccggccaa ggcccgctcc gacggcgacg atggccacca tgacgatgac ccggtggtca
    22021 tcgtcgggat ggcctgccgt taccccggcg gggtgagcac cccggaggag ctgtggcggc
    22081 tggtggccga cggcacggac gccatcggcc cgttccccgc cgaccggggg tgggacaccg
    22141 aagggctcta cgaccccgac cccggccgcc ccggccggac gtacgtgcgc gagggcggct
    22201 tcctccgggg cgcggaccgc ttcgatccgg gcttcttcgg catctcaccc cgcgaggcgc
    22261 tggcgatgga cccgcagcac cggctgctgc tggaagtggc ctgggaggcc ttcgaacggg
    22321 ccggagtcga cccccgggcc ctgcgcggct cgacgaccgg ggtgtacgcc gggctgatgt
    22381 acagcgacta cgccgcccgc ttcgcggtga cacccgcgca ggtggagggc tacctcggca
    22441 tcggcaacgc cggcagcgtc gcctccggcc gcatcgcgta caccttcggc ctggaggggc
    22501 cggcgatcac cgtggacacg gcctgctcct cgtccctggt ggccctgcac ctcgcggccc
    22561 aggcgctgcg ccgcggcgag tgcgccctcg cgctggccgg cggggtcacg gtgatgtcct
    22621 cgcccgcgtc gttcgtggag ttcagccggc agcgggcgct gtcgccggac ggccgctgca
    22681 aggcgttcgg ggcgggcgcc gacggcacgg gctgggccga gggcgccggg atgctgctgc
    22741 tgagccggct gtcgcacgcg cgccgtacgg gacttgaggt cctggccgtg gttcgcggct
    22801 cggcggtgaa ccaggacggc gcgagcaacg ggctgaccgc cccgcacggc ccggcgcagc
    22861 agcgggtgat ccgccaggcc ctggccgacg ccgggctggc gcccgccgac gtcgacgcgg
    22921 tcgaggcgca cggcaccggc acccggctcg gggacgtcat cgaggcggag gcgttcctgg
    22981 ccgtctacgg gcgggagtcg cggcaacgcc cgctctggct gggctcggtc aagtcgaaca
    23041 tcggccacac gcaggccgcc tccggggtgg ccggcgtgat caagacggtg caggcgatgg
    23101 cgcacggcgt gctcccgcgc acactgcacg cggacgagcc gaatccggcc gtggactggc
    23161 cgtccgggca ggtggcgctg ctgacccggc cggagccgtg gcccgaggcg gaccgcccgc
    23221 gccgggccgg ggtctcctcg ttcggcatca gcggcaccaa cgcgcacgtg gtcctggaag
    23281 aacccccgcc ccaggaccgc gcccaggccc ccggccccac acctccggca accccggtcc
    23341 cggtgccgtt cgtcctgtcg gcccggaccc gggccggact ccgggaccag gcccggcggc
    23401 tgtacgagca cgtgtccgcc gccccggacg tggagccggt cgacatcggc tactccctcg
    23461 ccaccacccg ctcggccttc gaacaccggg ccgtggccgt ggcccgggac cgcgcggaac
    23521 tgctcgcttc gctgcgggca ctggccggcg gcggagggcg ccgaccgggc acacacaccg
    23581 gcgcggcccg ccggcccggc cccctggcct tcctcttcac cgggcagggg agtcagcgcc
    23641 tcgggatggg ggcgcagttg tacggacagc ggtcgctgca tcccgccttc gcccgttcct
    23701 tcgacgagtc ctgcgcactg ttcgacccac tgctgccgag gcccttgcgg gacgtggtgt
    23761 tcgcccacga ggacagcgag gccggcgccc tcctgtggac gacccggttc gcgcaaccgg
    23821 cgctcttcgc cctggaaacg gccctgttcc ggctgctgga gtcctgggat gtgcgccccg
    23881 atctggtggc cgggcactcg atcggagagg tggccgcggc ccatgccgcc ggagtgctgt
    23941 ccctcgcgga cgcatgcacc ctggtggcgg cccgggggcg gctgatggac gcgctgccgg
    24001 gcggcgcgat ggctgccgtg gcggccggtg aggacgaggt cgccgcccat ctggcgcagg
    24061 cgcgaggggc agtggagatc gccgccgtca acgggcccgc cgcggtggtc gtctccggtg
    24121 acgaagccgc ggtgcgcgag accgtcgcgt acttccgcga tcggggccgg gccacggcgc
    24181 cgttgcgcgt gagccacgcc ttccactcgg ttcacatgga gcccatgctg gccgagttcg
    24241 ccgaggtggt gaggggcctg tccttcaccg accccgcgat tgcgctggtc accgccgtgg
    24301 cggggcgtgc ggccaccgat gaggagctgc gcgccccgga gttctgggtg gaccacgtgc
    24361 gccgaccggt ccggttcgcc gactcgctgg cccacctccg cgcgcggggg gcggcccact
    24421 tcgtggaagt gggcccggac ggcgtactca ccggcctggc gcgcacctgc ctcaccacac
    24481 cggagccgct gcctgcgacg gccccggcac cccggacgac cccgcccccg gcgccgcccg
    24541 caaccgccga cgcacccgag gccggcgcgc ctgccgccga cgcgcccgcg ccgctgatcc
    24601 tcccgacgct gcgcggcgcg cggccggagg cgggcgcgtt gctcgacacc gtggccgcgc
    24661 tgcacgcgca cggcgtcccg gtcgactggc gagccgtctt caccgggcgc ggcgcgcgcc
    24721 gcaccgcgct gcccacgtac gccttccagc gccgccggta ctggctggac gccgacccgc
    24781 cgcagcagcc cgcgctcgta cccgtacccg catctgcgtc cgggcccgcg ccggccggtc
    24841 cgccccactc gttcctgcgc tcccggacgg tcacggccga cgacgacggc ctgttgctcg
    24901 gcggcctcct ctcgccgcgc gaccatccct ggctggccga ccacaccgtc gcgggggacg
    24961 tcctgctgcc cgggaccgcg ttcgtggaga tggccctgta cgcgggcgag caggcgggga
    25021 cgccggtcgt cgacgaactc accctgaccg cacccctgcc gctgcccccg gacgggagcg
    25081 tcgagctcca gatgaaggtg gcgggagcgg acggcgtggg ccggcgtgcc ctcaccgtcc
    25141 acgcccgcct ccacgacgcc gaggcggctc ccggcccctg gcgccggcac gccacggcga
    25201 ccctcgtagc ggcaggagac caaccggccc aggagccgtc cgtcaccccg gcggcggacc
    25261 acccctggcc cccgccgggc gcggtcccgc tcgacctcga cgggcccccg gaggcgcggc
    25321 cgccgggcgg cgcgtacgca cgcctggccc gcgccggact ccactacggg cccgccttcc
    25381 gggggctgcg cgccgcctgg cgcctcggtg acgaggtgta cgccgaggtg accctccccg
    25441 aggccgccga ggcccccgcg ccgggggagg gtgcggcggg cttcgccctg cacccggcgc
    25501 tgttcgacgc ggcgctgcac acggtggcgc tcgccgggct cccgccggca caggaccagc
    25561 cgccgggaga ggacaaggct ccgcccgagg acgcactgga cgggggagcc gcggccctgc
    25621 cgttctcctt cgccggggta cgtctgtact cctgcggtgc gcggcggctg cgggtacgca
    25681 tgacgccggc cgccgcggcc gggcgcggcg agacggcgga cgcgcagccc ggccgagcgg
    25741 tttccggcac cgagggtggg atcggcctgg aactggccga cgagacgggc gcgcccgtgg
    25801 ccacgatccg ccggctgttc ctgcgcccct tgccgcgtac cggctccggc gcggtgcgaa
    25861 cccccgccgc ctcgctcttc cgggtggact ggacgcgttc gccgcagccg ctcgcggcct
    25921 ctccggtgcc gacgtggggc gtgctggccg gagccgacgc cgggccacag gatgtcctgg
    25981 cgcccgcgag ccaggacatc ccggtgtaca ccgacctcgc ggcggcggcc gccgccgcac
    26041 cggaggtcgt cgtcgccccc tgcccggggc tcccggcggc cgacggcgac gtggagccgg
    26101 ccgggcaggt gcaccggacg gcgcgatggg ccctcgccct ggtgcaggcg tggctcgcgg
    26161 agccccggct ggccggctca cgcctcgtcg tcgtcaccac ccacgccgtc gactccggca
    26221 ccgccgactc cggcaccgcc gacaccggtg ccggtatcag caccgcccag gcggccgtgt
    26281 ggggactgat ccgctcggcg cagcgcgaga acccgggccg cttcgccctg atcgacctgg
    26341 acggcggccc cgattccgcg gccgcgctgc ccgcgctcct gtcgggcgcg cgacccgaga
    26401 cggcggtacg gcggggagtg gctcacgtac cggaaatcgt ccgcgtaccc gggcccgcgg
    26461 cgaacgcgcc gcttcccgta cgccggctcg acccggaggg caccgtcctg gtcactggtg
    26521 cgaccggctc gctgggcatg atggcggccc gccacctcgt caccgcgtac ggcgtccgcc
    26581 atctgctgct cgccgcccga cgcggctccg atgcgcccgg gatgaccgaa ctgtgctccg
    26641 aactggcgga cttgggcgcc cgggtcacgg tgcgggcgtg cgacgtcgcc gaccggcggg
    26701 cactcgccgc cctgctcggc gaggtaccgg cggagcaccc gctgaccggc gtggtgcaca
    26761 ccgcgggggt tctcgacgac ggcatcgtcg ccgcgctcga cgatgcacgg ctcgaccgtg
    26821 tgctgcgccc caaggcggac gccgccctcg ccctgcacga gctgaccgcg gaccgtgaac
    26881 ttgcgctgtt cgtcctcttc tcctcggtgg ccggggtgtt cggctccgcc ggtcaggcgg
    26941 gctacgcggc tgccaactgc gtcctggacg ccctggcccg agagcgccga cggctcgccc
    27001 tgccgggcac atcgatcgcc tgggggcctt ggcggcagag cggcggcatg atggcgcacc
    27061 tcacggagct ggacctgcgg cggatggccc gcgccggatt cgccccgctc acaccggacg
    27121 agggcctcgc gctgttcgac gcggctgtcc gtggcgccga cccggccccg gtggcggccc
    27181 gcctcgatcc gtccctcgcg ccgggcgggt cctcccgtag ggccgtcacc ccaccggccg
    27241 ggaccggacc ggccgccgcg agcgggccgt ccggtgcgcc ggccgcggac ccgctcgtcc
    27301 ggcggcttgc cgccgcgacc ccgggcgagc gcggcgccct gctgctcgcc gaggtgggcg
    27361 cgctggctgc cgaggtcctc ggccacaccg agcacgacga gacgatcgac ccggacgacc
    27421 tgctggcgga ctggggactc gactccctgg ccgcggtcga gctgcgcaac cgcctcgcga
    27481 ccgcgacgga caccgtgctc ccgcccaccc tgttgttcga cttcccgacc ccgcgcgcgg
    27541 tcgccactca cctggcgcag cagtacgtac cccacccgac gcacccggcc ccggtcgccg
    27601 ccgcgtcggc ggccgccgaa gaactgcccg attcactggc cggcctcttc cgtaccgcct
    27661 gtgagcgagg gcggaccatg gaggcgatgg ggctgctcac catcaccgcg cgcctgcgcc
    27721 cggtcttcga ccgcgccgaa gcgccgggcg cggtgccggc ggccgtcccg ctcgcctccg
    27781 gcggaacggg accgcacctg ctctgtttcc cggcgctcag cgcgctctcc ggaccgcagg
    27841 agtacgcccg cctcgcccgg ggactggccg gcctgcggcc ggtcacggcc ctgccgcatc
    27901 ccgggttcca gcgcgcggaa cggcttccgg ccactctgga cgccttcgtc accgcccagg
    27961 cagccgccgt cctcgcagcc gcggacggtg aaccgttcgc cctcctcggg cgctcggcgg
    28021 gcgggtgggc ggcccaggcc gtggcacagc ggctggcgga cgaggacgcc gccccggtcg
    28081 ccgtcgtcct cctggacacc tatcccgccg cccgcgcaga ccgcgacgaa gccctcgccc
    28141 cgatgacggc cgacatgctg cgccaagcgg cccggttcgc ctcccacgac cccgaccggc
    28201 tgaccgccat ggccggctac ttctccctgt actccggctg gcggcccgaa cggccggcgg
    28261 ccccgaccct cttcgtccgg gccggggaac cgctgcccgg caccgcaccg gcccccgcct
    28321 ggccccttcc ccacaccgaa atcaccgtcc caggcgacca cttcaccctt ctggagggac
    28381 acgcccgctc caccgcccgc accgtccacg actggctggc cgaactgccc caccagtgac
    28441 ctcgccctga ccacccacgc ccccggcccg ctcggaacct ccgcccgagc ggctcccgga
    28501 ctcctctcgg agtcgtacga ccgtgcgcgc ccaccggcac ggtgtcgaac gtgttcgggc
    28561 gtcggatctg ccgagtccgg ggaacttcac cgcccggggg agaggaaacg atcgtccccg
    28621 gcacggggcg ccctaccgtg gagtggatga agcgcctgtc agccggctta tcggcggccg
    28681 cagccctgct cctgaccgct ccgccgccgg cggcagtcgc tgcggccgcg ccgtgtgtca
    28741 ggggcgagtc ggagtcgagg ctgcgcagct cggtggatga cggcgagatc agatggaccg
    28801 cgaacacggc ctacgcggac gcgtacaagc acgcgctcaa ggcatggcag tacggcggcc
    28861 acaagatcag attggcgccg gattcggcga ccacggtcaa cgacctggag ttcacggact
    28921 acaacgaccc gcaggaccac gccgccgcga agtggaacta ccggagtggc cccggccaga
    28981 ccgactacat ccgcttcaac accgcggcga tgaagaacgc gagccggacc aagcgccggc
    29041 agatcgcggc acacgagctg ggccacgccc tggggctgtg ccacaagtcg gacgccggcg
    29101 ggccgggcta tgtgcggtcg ctgatgtggc cgaccgccca cgaatacttc gatctccctc
    29161 aggacgtcga ccgggccaac tactccaagc tgtggggctg atcatgaacg tgaagacgtg
    29221 ggcggcggcc gggaccgcgg ccgcggtgct cctaggcggt ggctggtact cctgggagcg
    29281 cggcagcgcc ccgcatacgg agagcctgtg cgggacgccg tcgggtggca cggacgccga
    29341 ggtggcgacc agcgcgcagg gcattgccgt ggtggaggcc gtcggcgcgg cggcacacga
    29401 cccgcgggcc gtcggcgccg agaaccccga gctcgtcacc actccggtac gggtcgtggc
    29461 gacgatgaag ggagacttcg ccccgagtat cggggtgtcg cagcgggttg aacccggcgg
    29521 ggcccccggc tccttcgagc tggccacctc gaaccgagaa gtgatcatga agccggggga
    29581 gcgctacgtg gtcgcgatcg gccccggcga cctgaaggcc cggccgggaa cgacgacatt
    29641 cgccaccttc atccagcccg cccgccgcgg cccggccggg gaggccgact actggcggaa
    29701 cgtgatcgct acggcgcccc caaagcccat ctgcgacgac accgccggct aacggaggag
    29761 gacagcaggc gcgcgaccgg cggttgtgat gaggccggcc ccggttaggt ctcggagcac
    29821 gccaggaccc atccctcgtc gtgggatacg aacgaaaggg ctcgcacttc ctggccttcc
    29881 tcggcctggc cgccaccctg acctgctact ggaagctcgc gaaacatgcc acgtgagaca
    29941 ccctccaact agctgtgaca gcgcccctca tgacaatcag cagttgcggt gatggttcac
    30001 ttgccagaca gttcggggtg gccggggagg gcgtgtggaa gagccggggt tccgtgtact
    30061 gctgagggag gcaggtgacc ggaagatgga ggcggtccgt gcggtccgga cggtcaccgg
    30121 cctcagtctc tggaacagca aacttctgct cgacagcgcg cccgtagtgg tcacaggccc
    30181 caactggctc gaagtcgcag atgaggcggc ccggctcctt gaggacgcgg gcgcccgtgc
    30241 ggcagtgctg tgcgactggt gcgaccgcac catcacgcga ggggccgacc ctatggaccc
    30301 ggccccgtgc aaggggccct ggccggccga ggcctgccgg gcgagttgcc caccggcctc
    30361 gccctgagca tcggcgggca cagcccagaa cttctccggc cacatgcccc ggctgggccg
    30421 acgcgccggc caatcgcatc agccgtccgt ccacaggaac gcccgtagat cagtgccgct
    30481 tcccgcaggg gtgcagcggc cggctgatgg ccgcgactgt cgtccgctgg ccttcccgcg
    30541 cgggagaccg tccgccggtc actggccggt cggcggctgc tcggtgccga accggctctg
    30601 ttcgatggtc ttcgcgcggg gaacctccgg gttcatcccc ttgtgccatt cgctctcgcc
    30661 gagccggccg cgcaggtgct cgacggtgtt ctcgacgtgg tcgcgcagcg cccggaggtc
    30721 gattccccgg agccggtggc ggtacttggc gacgtggccg ttgaccagga cggtgtggac
    30781 gtcggatcgc tgcgcctgga gcacgacgtg cccgtgcggg ttcaggagcg ggaaggagac
    30841 gggggagtcg tcgttcttga gcaggaccag gtcggccttc ttgccgacct cgatggtgcc
    30901 caggtcgtgg gagcggccga gggcggccgc gccgccgcgg gtcgcccagc tcagcacgtc
    30961 gtgggcgcgc agtgtcgtgt gggtgacgct ctcgccccgg gcatggcctt cagcgtgttc
    31021 gcgggagcgg tcggcggcca gagtggcgcg catcgcggag aagaggtcgg cgctccacca
    31081 cacgctggtg tccatcgaca gggacacggg gatgccgtgg gcacgggcgg cgtgggtggg
    31141 agggtatccc tgcccggcgt gctgctcgct ctcggcagag atcgacaggt acccgccggt
    31201 gtccgcgatg cggcggtagg agtcgtcgcc cagggacgag ccgtggacgt agacggtgcc
    31261 cgggcgcatg catccgtgct ggtggagcat ggtcatgctc cggtccagag cggtgcccca
    31321 gaccccggcg tgggtggtca cggcgacgcc caggtcgcgg gcggcttcga aggccggctt
    31381 ctcggggaac gaggggtcgc cgcccaggtc gatggccagt tgcaggtcca gcatgccgtc
    31441 acgggggacg cgctggtcga ggaaggcacg gaaggcgggg tcggtggccc actcggcggc
    31501 gggccggtgg aggttgccgt aggcgaggac gaagcgcccc ggcaccgcct ggagcgcgtc
    31561 gaccgcggcg tgggcgtggt cggtggtggc cagcccgtgt gaccagtcga cggtcgtggt
    31621 caccccggcg tccagggcct cggcggcggc gagcaggttg ccggcgtgga tgtcctgggg
    31681 ccggaagtgc ttgccgtggt cgatgaagaa ccacacgaag tactggctca gggtccagtc
    31741 cgcgccgtag ccgcgcagcg cggtctgcca catgtggcgg tgtgtgtcga tcatgccggg
    31801 tatgacgatt ccgctgctgg cgtcgatgac ggcgctgccc ggaggcacgg cgaggtcggg
    31861 tccgatcgcg gtgatgcggt ctccctggac caggacgtcc gtgttggtga gtacccggcg
    31921 ggggtcgtcc atcggcagca ccgtgccgcc ccgcaggagt accgggcgcc cgttgccgaa
    31981 cgtgtccgtg tcggacatgt cgtcacctca tcttcttgaa gtcgtcgaat ctgtgcccgc
    32041 cctacggaca ccgggcggga tcggttcgcg cagcaccggc acatcaccgc ccggcccggt
    32101 cgtaggcccg gtcccggaac cggtggtgcc cccgccccgt agagcggatc gggcaccgcc
    32161 ggtggggtgc cccggattca ccacacggat gaggagagac gcgcatggcg aacatcgtga
    32221 tcatcggcgg gaccagcggc attggaaggg agctggccgg gcacctcgcg gggcagggcg
    32281 acagcgtggt gctgaccggc cgggacgcgg agcgcgcgcg acaggtggcg cgggaggtgg
    32341 ggaaggggcg ccaccacgtg cggggcatcg ccctggacct cgctgagccg cacgagatcg
    32401 cccgggcact gtcggggacc ggcccggtcg accacctggt gatcacggcc gtggaacgag
    32461 acgtgaacag cgtgcgggac tactcggtgg accgggcggt gcgcctggcc acgctcaagg
    32521 tggtcggata caccgccgcc gtcgcggccc tgcgagaggt gctggcgccg accgcgtcgg
    32581 tcgtcctgtt cgggggcgtc gcgaaggacg cgccctaccc aggctccacg accgtcacgg
    32641 cggtcaacgg cgccgtggtc tccatggtgc ggaccctgtc tacggagctc gcaccggtga
    32701 gggtcaatgc cgtacacccc gggatcgtca gcgacacgcc gtcgtggagc gggcaggcgg
    32761 acgttctgga gtcggtccgc ttacgtacgc ccaccggccg gctcgccacc atggccgaca
    32821 tcgtcggcgc cacggtcttc ctgatgcaca acccggccgt gaaccgagtg aacctgaccg
    32881 tggacggcgg catggtgtaa ccggccggcc ccgccggccc cgtcggatcc tgcctgtccg
    32941 gaggctgcga cagtctccgg acaggcaggg aaagcgtgct gtaagcggcc ggcaagcgcc
    33001 gcggcgaacg ctggccgggt gatgaccact tcgcccacac aggcagcctc acccacacca
    33061 gccgtgtcac ccgccgcagc tcgacgcacc gaagccgacg acgagtgttt cgtccgcgcc
    33121 gtgtacgaca agcacggcgc catgctccgg cacgtcgccg cccgctcgct gggcggcgac
    33181 gtgcaccgcg ccgaggacat cgtccaggag gcgatcctcc gcgcctggca ccacgccccg
    33241 ctcctggacc gggccggaga gggcatccgc ggctggctcg tcaccgttgt ccgcaacctg
    33301 gccatcgaca gccaccgcgc ccgccgggcc cgcccgtacg aaagtggcga cctcgacgtg
    33361 gtggagcctg cctcaccggg ccacgaggac cgcgcgaccg accgcctcgt ggtccgcgag
    33421 gccctggggg agctcagtga accgcaccgc cagatcctgc tgtacacgcg ctacctcgac
    33481 aagtcggtcg ccgagaccgc cctggccctg ggcatagccc ccggcaccgt gaagtcccgc
    33541 acccatgccg ctctgcgcgc cctcgaaggg gccctgctca gacgcggata cgtgccggcc
    33601 gccggccgcc gggcgcccac cgggcgccgg agcccgtcag cagaaggccg cccgcaccga
    33661 cggcgagcgg gcgagacgct cgtgcagtgc gtagcgccgt cccggttcgg tgctgccccg
    33721 ctcggtggcc tcggtcagca gcaggccgac cgcgtcccgg gccagcggct cgatgatcgc
    33781 ggcggcctcg cggcgcccat cggcgagccg ctcaccgtca gccggcccgc cgtcgccgca
    33841 gaccgtgagg gcgagggagg cgacggcccg gcggtggcgc ggggcggctt ccgcgctcgc
    33901 cacctccctg agggccgccg ccgcctcggt gaaccgggag cgggcggcga ggaccaccgc
    33961 gcgcaggttc gcccccgcgt aggcgaggtc gtaggagatg acttcggcgg cgatccgctc
    34021 cacctcggcg atgcggcggt cggcgcggtc gtggtccccc tccccgatgt ccaggtaggc
    34081 cagccgcagc gcgcggtagg cccagcgcga tcgggcgtcc atggtccgca ggatctcgct
    34141 cgcctcgctc cacaggctgc gggcctcctc ccgccggccg gcgctctcct gcgcgtcgcc
    34201 gcgggcggtg aggcagatcg cgagggcgaa ggggtcgtcg gcggcgcggg ccgcctcgat
    34261 gccgtacagc gcgtgctcgc ccgccgcgtc cgggtccccg ttgtgcaggc agtaggtcga
    34321 ccagttgtac tgcagcacgg cccggtccca ctggaacgcg gtgccggcga tgccggcctc
    34381 ggcccgcgcg aacaggtcgc cgcggtcctc gtcggcagtg agccgcgcgt acaacgcctc
    34441 gtagaccggg ccgatcaccg ccacgtcggg gttgcgggcc tgccgccagg cggcccggta
    34501 gcgctcctcg tagccgagcg cgctctcgtg ccgcccggcg acgtggttga gccaggcgag
    34561 ccacgcgaac gtgtaagtga gcgcccactc ctcccgcggg ccgggcgggc gttcggggtc
    34621 cgaggtgccc ggttcgctgt cgtaggcgtc cagggtccgg gcgagccggt cgatgccctc
    34681 ctcctcacgg cccgagacgt accagaagta gccgagggag gattcgagga acagggcttc
    34741 ggctgcgcgg ccctgccgga ccagcagttc ggagccggcc ctgagattgg ccgtctcctc
    34801 ggcgatgtgc aggcagtggg cgctctgttc gcgtgagtgg agggccgccg agtgttcggc
    34861 ggcgaagtcg agtgcccagg agacgaagcg ctcctcggcc tgctgcagac ggccttcggt
    34921 ccgcaggcgg gcaagggcgt actcgcgcac cgtctccagc atctggaaac gggtgccctg
    34981 cgcgccgggt acggtgaaca gcattgattt gtcgaccagt tgggtgagga tcggcagcag
    35041 gccgccgccg tggccggcgg tgggggtccc ggtcgtctcc gggccgggcg ggccggtccg
    35101 ctcggcgtcg tcgagcgcgg ttccgcccac ccgcagggcg agttcgctca ggacctcctg
    35161 ctcggcgccg ccgagcagcg cgtaactcca atcgaggacc gcccgcagcg tgcggtgccg
    35221 ggcgggcgcc gtgcgctctc ccttcaccag gagggcgaag cggtcatcca gcctgcggtc
    35281 gatctccgcc acggagagca tccggacgtg ggcggcggcg agctcgacgg cgagcgggag
    35341 tccgtcgaga cgacggcaca gggtcagcac gtcctggcgc gcgtccggcc ccgccgcgaa
    35401 cgaagggttg atcttggcgg cgcgcagggt gaacagttcc ccggcctcct cggcggtcat
    35461 cggctccacc gtgaagtggg cctcgtacgc gatgcccagc ggctccctgc tggtggccac
    35521 cacggtgagt tgcgggcagg cgtcgagaag cgtcttgacc aggggcgcga ccgcgtccag
    35581 gacgtgctcg cagttgtcga acgccacgat cgtcgtgcgg ttctccaacg aggagacgac
    35641 gcgccgcagg aagtccaggg ggcgctggtc ggtggccacc gacgcgtccg acagcccgag
    35701 cgtggtggcc agcgccgcga ggacgccgtc ctcaccggtg acggccaggt cgatccacca
    35761 gagggcctcc acgggggagt ccggccggga gagtgcctcc agcgcgagcc gggtcttgcc
    35821 gaccccgccg ggacccagca gcgtcaccag gcgctcccgg atgatcgtct cccgcagggc
    35881 ccgcagggcg ccgcgccggc cgacgtacgg ccccggggac cggctcaggt tgccctccgt
    35941 cttcccggag ccggagcgcg cggaggccgg cgggcgctcc gccgcctcgc ttcggacgac
    36001 gttggaagtc atcagggcag ggtcgtgttc gaggatcgcg ctctgcaggg cgcgcaactc
    36061 gggtgagggc gccaggccga gctcggcgtc cagcagcacg cgcccgtggt ggaacaggtc
    36121 gagtgcttcg gcatgccggc cgctgcggta gagggccagc atcagctggc cacgcagctt
    36181 ctcccggaag ggatgatccg ccagcagggt ggtgagttcg gatatcagct cctgggcccg
    36241 gccccgttcg agtcccacat gggccgcgtc ctccagggcg gtgagccgca gttcgtccag
    36301 ccggcggcgc tcgccctcga acaccatgcc ggtcagatcc tccagcgccc gcccccgcca
    36361 caggtccagg ccgcttcgca gaagctcctc tgcctcctcg tgggctccgg cccgcaggcg
    36421 ttcccggccc cggcggacgc tggtttcgaa gacggtgaca tcgacgtggt cctcgtcgtc
    36481 cagggcgagc cggtagccgc cggccagcat cgccagacgg cccgcctcgc cccgttcggc
    36541 gaacgcggtg cgcagcttgg tcatctgcac ctggagcgcg ttgacggggt tcctggcccc
    36601 gcgctcgctc cacagctcgt cgatgagggc atcgcgtggg acgggccgtc cgccggccag
    36661 cgtcaggcgg gcgacgatcg ccctggcgag ggaacccgag agggcgatcg gggatccgtc
    36721 ggaggcagtc acgtcgaggc gtccgagcag gcgaaagtgc atacgtgagt atcccgtgcc
    36781 aggaggggtg agccggccgt acccgcaccg gctcttgcgt ggtggtgggc gggaccggtg
    36841 cgcggagcac cggccctgcg gtctcaaacg gtctgccggt cggggcggac gggcgcgctg
    36901 ccgcccgccg ggcgggttgg cgcccgtccg ccccggaggt tgcgtcagcc gaggaagcgg
    36961 atggacttca cggccgggaa cccgacggcg gccaggtccc gcacatcacc ctggacgagg
    37021 agggacttgc ccgtgcagtt cgggccgtcc cagatcttgg ccgcgccgcc tatccggagc
    37081 gagccggaga agcggaccgg cttgcagtca ggtccggtga tcccctcggc cgggtcggcg
    37141 aagtccgccg agtcgaagaa cgtggcgttc cgcgcgggcg ccgccggcgc agtcgtggag
    37201 gtgacaggag gggtgccggt gccaccgggc tgcccggcct tctttccgtc cggcgtcacc
    37261 ccgaaccagg tgccgcccac gccctgcccg ttggtgtcgc cgggcttggt gtccttgctg
    37321 aacaggtaga cgggccagcc gccgatcgtc acctgcaagg cgccgtcgcg cgggataaaa
    37381 ccgatggccg agggctggat cccgtcgatg aagaccttgc cgccgttggc gaccaggtac
    37441 ggcggccagg tgtcggcgca cgcaccggag cagttggact tcgaagggtt cgccgtgtcc
    37501 ttgtcgaagc ggtacagcgt gaacccggcc ccgttgagca ccacggggtc gagcgcaccg
    37561 gccttgccgg aggacagctg cacccacgcg cgggccaccg gcttcttcgc ggccgcggcc
    37621 acggcggggg ccgcggcctc cgcgaggtcg ccgctgttcg ggtcggcgcc gttctggcgg
    37681 gcggtgccgc tcaggaggga caggcccgca gcgccggctg cggcggcgct cggggaggcc
    37741 gccgccccgg cgtccccgct tgcacgggcg gcggccccgc cgctgccgtc cgtcccctcg
    37801 caggcggaga gcaggaggat tgcggcggtc gagagggcag cgagcgaagt ggcacgagcg
    37861 gtacggaaca tcagaactcc tggtgacggt ggcctggttg gcggccccgg ctcctccggg
    37921 gcgatgacac cacccgtccg gggcggtggc accacccctg ctacggacct caccccggaa
    37981 aggttctgac gccttgtagc ccggggagca ccggcccgga aggagcggac cgcggagctg
    38041 cccggggagg cgagccacca cgggtgtccg tcagcgtgcg gacagtgccg ggaaagcgcc
    38101 gggacagcaa ccggcctttc gatgctccca gggcaggccg cagcgcgacg acaccgtcat
    38161 cgcggacccg cccaccccca ccggtcacct cgccaacgaa ggacggcaca gcacatgagc
    38221 caggaatcca cgcacaccct gatccagcag gccgtcgaag agctggagca gctcaaagcg
    38281 aatgtctcgg ggagggtctg cacccccggc gacccccact acgcgcggga agtgtccgcg
    38341 ttcaacctgc gctcgcagat ccgccccgcg ttcgtggtcg ccgccgagac gcccgaagac
    38401 gtgcagatcg cggtccggtt cgccgccgcc cacgggctcg cggtgggcgt cctgtcgacc
    38461 gggcaccacg ccttcccgcc gcagacgagc cacggagccg tcctgatcac cacccgcacc
    38521 atgcggaccg tacggatcga cgcggcaacg gcgagcgccc gcgtcggggc cggggcgctg
    38581 tggagtgacg tggtcgggcc ggcccagcgc tacggactgg ccccgctgaa cggctccagc
    38641 gccggtgtgg gtgtcgtcgg atacacgctc ggcggcggcc tcagcccggt cctgggccgt
    38701 gcctacggct gggccgccga tcacgtccgc gccatcgacg tcgtcacggc cgacggcgaa
    38761 ctgcgccacg tcaccgagca gtcggacccc gccttgttct ggggacttcg cggaggcggc
    38821 agcaacctgg gcatcgtgac gtccctggag ttcgacctgt tcccggtcac caccttctac
    38881 ggcggcggca tcttccaccc ggcggagcac gccgaggccg tgctgcacgc ctaccggcag
    38941 gtcgtggaga acgctcccga cgagctgacg gtctcggtcg ccctgctgaa cttcccgccg
    39001 atcccagagg tcccggagct gctgcgcggc cggttcaccg ttcacgtccg ggtggcctac
    39061 ctcggctcgg acaccgaggc ggaggcgctc atcgcaccgt tgcgcgcggt cggcgccccg
    39121 ctggcggaca cggtcggccg gcgcggctac gacacgttcg ccgaggtgca ccaggacccg
    39181 acggacccgg ctccgtacga ggaccgcagc gtgctgctga cggagctgac ccccgaggtg
    39241 gtcgcggcgg tgctggaacg ggtcggaccg gcctccggca gtgtggtcac cgtgctggag
    39301 atccggcacc tggccggcgc cctgagccgg gaagcaggcc tgcccagcgc cgcgggcgca
    39361 cgggacgccg ccttcatggt gtggggtgcg acggtgggtc cgccggaggt ggtcgaagcc
    39421 ggaaccgggg acatgaacac gctgctcaag gacctcactc cctggtccac cgggcgcctg
    39481 taccagaact tcacgtcccg ggaggccgtc gcttccgacg tgttcgcccc ggacgtcctg
    39541 gcccgcctgc agcgcatcaa gcagcagtac gacccgcgga acgtcttccg tgcccacaac
    39601 cacaacatcg cgccgacacc gggccccgcc gcgcgctgac cttcgacact gcggctcacc
    39661 gggacagcct ggtggtggac tcaggctgtg cggcggtgac gcagcgcatg gcggcgccgc
    39721 cgctcagacc gaacagccgc atgaggggag atccgaaggg cgatcattga cttcatggac
    39781 catcccgtgc ctctcagcag tttcggactg cggttcgccg taccgcagcg ccctcacgcg
    39841 atggagcagt gggcggaggt gcgtccgctc gccgacggcc gggacctgct ggcggagatc
    39901 cacccggacg gcacgtcaag ctgctcaagc cggcatttga tcggccctgt caggggatgg
    39961 cccttcgcgg ccttggacga accgcgccgg gtcgagctgt ccaacaacga ctgcgtcacc
    40021 agctgttgcg ggggcatctt cgtcaccatc cgacgccagg gcgaccgcgt gctctggacg
    40081 tctgggagaa cacggaggac aaccgggatc cccttcccgc tgacctgcac ttcgacgcgg
    40141 cccagtacga cgccgaactg gccagggcag gctcggatgt cagctgggag ggacccgtgg
    40201 acaccgcggc ccggctgctg gcccaggaac tcgccgacca cacgggcccg gaggccggag
    40261 agcacgcggt gctctccatc acacccgagc gcacggatcc cccacgcgtg acggtccgca
    40321 tgcgccgccg cgatgctcca cggacacctg gagaggatct ggtccacgaa ctgctcttga
    40381 ccgatcggga acccgtccaa gaactcgtcc agcggctcgt cctcaggctc acggcccagg
    40441 accacggcga cccgtccggt ccgcggtgag tgccctgtcg ctgacctcct gcacctactg
    40501 agaccagact gcacctggcc gtcgagcagg gccagaagcc catttcggcc ggtggtcttt
    40561 cactgatcct tcgcttcgaa tgcctgggcg acggccaggc tgtcctcgta gacatggtgc
    40621 cgggtgacaa ggccgtctgt gacggtgaga tgcagagcga accgcgcctt gtaggcacgt
    40681 ccggtgggcc gggcggtctg acgaatctcg cccagcacga ccgcgtcgct tccgtcgaca
    40741 aggatgcgct cgacctcggt cgccacgtgc tccggcacgt ggtactcggc aagctcgcga
    40801 tagtgggcgg ccgcgtcagc ccgggtggac cggtgacgga tccacggtgt ggcagtacgg
    40861 ccgtgctcgg cctccggcca gtcgagcttc cagtcaccct gctcggcgta cagctcggcg
    40921 atgcgctcgg ggttgccctc gccaatcctg cgcagcaact cctccaccac agtgcgcgtg
    40981 ttcgatggtg tggctatgga catggctggc tcctccgtcc tggtccgcgt cctccgacgc
    41041 ggagagatca ccaaccctgc cagcacgggc acgccgagac cattacctcg aacgtaaggc
    41101 gagcggatca cgaagatcca ctttcgatac gcgccccaat tggcggacga gcgcttgaga
    41161 tggcggggga ggccttgcgt cagtggtcgc ggcaagggcg ccgtcgcgct cctgagcggg
    41221 gaaaaccact ttggggcacc gggtggacct ggcaggcttg cgcggtgatc gttgagatgg
    41281 ctcctcgctt cctgaccagg gacgacgtgg accccacccg tcaagccgac gacggcaacg
    41341 cccgctccgc tcggcatcga gctgagcgcc tcagtggggt cgcctgagct ccaggcgctg
    41401 cacagcaagg cagaccagca ggtgggtgcc gaccggttgc accgaagccg atcactaggc
    41461 tcccgccatg accagtgatc tcggattcag ctgctcgtgc tgcggcgcgc accaccctga
    41521 gctgcccatg aactacacgg ccgaggcccc attcgtctgg gatccggcct tcgccgacgc
    41581 cgacgactgc ctgctctcgt cagaccagtg cgtgatccag gcggagcact acttcgtcaa
    41641 aggcctgatc gagataccgg tgatcggtag cgacgaggtg ttctcctggg gtgcgtgggt
    41701 gtctctcagt cgcgagaact tctcccgcgc ggcggacctg tgggacacgc caggccggga
    41761 gtccgaagag ccgtacttcg gctggctcac aaccgacctg ctcgtctact cgcccacgac
    41821 cctcaacctc aagacccacg tccacacccg cccgatcggc cagcgtcccc tcatcgagct
    41881 cgaacccacc gaccaccctc tcgccgttga acagcgcacg gggatcaccc aggaccgcgt
    41941 gcgggatatc gccgcggcag tgctgcaccc ctcccgcggc gagaggcgga agtgacgggg
    42001 gcaaggcggc tgccgcacgg gcgggggcga ccgtgatgtg gatcacaggg gctggacctc
    42061 agccttggtt gagggagcag ggttctgtgc agcaggggcg ccccgcaggg tggcccagga
    42121 cctgcctatc aaggagcctt tgatgtctga cagccgtgtc attgtggtga ctggtgcgac
    42181 cggacggcag ggcggtgcca ccgcacgcgc actgctctct cgcggctgga ccgtgcacgc
    42241 actggtccgt gacccgaaca agcccgaggc gctggcgctg aaggaggccg gcgccgtcct
    42301 ggtccgcggc aacctggacg acgtggcatc actggacaca gccctgcgcg gcgcgtacgg
    42361 ggtgttcagc gtgcagacct tcgctggacc ggacggcttc gccggcgaga tccggcaggg
    42421 caaggccgtt gcggaggcgg ccgcccgcgc gggtgtcgcg cacttcgtct acagctcggt
    42481 cgatggcgcc gaccgccccg gccaggtgcg gcacttcgcc agcaaaggtg aagtcgagcg
    42541 gcacatcatg acgctcggtc tgcccgcgac gatcctgcgg ccaaccttct tcatcaccaa
    42601 cttcgagcac ttgggccccc agtgggtgga cggcgagctc acgctgacga tggcgctggc
    42661 cccggacacg aagctacaga tgatcactcc gggcgacatc ggaagcatcg ccgccgatgc
    42721 attcgacacc ccgggcgact acctggggcg caccgtcgag atcgccgcgg acgagctgac
    42781 cggcccacag ctggccgaag ccttcgctcg cgccgccgcc cgtccggtgc acttcacctc
    42841 ccagccgatc gagcaggtac gcgcccacag cgaggagctg gccgccatgt tcgactggtt
    42901 caacacggtc ggcttcaagg ccgacctggc gacgctgcgt gcacagcacc ccgggctgac
    42961 gtccctggaa gcgtgggtgg acgcatactg gtcagcgcct gccgcacctg ccgcaccagc
    43021 cctcgtggcc tgaggcacgc gcaaccgagg ctggagacgc tctagaaggc gtccgccccg
    43081 gccaggtctt ccgcccgggc ctgcccgcgg aaggccgcgg gcggcacgcc gtaagcctcg
    43141 cggaacgccc ggctgaacgc ggacgcgtgc cggaagcccc gccgggcgcc gatgacgtgc
    43201 acgggcacct cctggtgcag cgggtccgcc aggtcctggc gtgcccgcgc gagccgctgg
    43261 ccctgaagga aggccgcgac cgtcaccccg tccccctcct gctggaacac ccggtggagg
    43321 tagctgacgg agatgtggtg ggcggcggcg atcgcgggga cgtccagcag cggatcgtcg
    43381 gcgttgtccc ggatgaaggc catcacgcgg agcgccagtg cgcgacggtg cgtctccggg
    43441 gtcaaggacc ggtccgcttc gaggacgccg gcgaagagcg aggctacgag atcggccagt
    43501 acgccgctca ggcgcgggcc ctccgcttcc cgataggacc ggctgtcctt ggtcacctgg
    43561 tcgaggaagg tggccaccag ggcccccatt ccctcccgag ccgagatgcg cttgccgatg
    43621 acccggccgg cgatgtgcgg gggcagcggc agcagcgcct tgggtacctc gaccccgatg
    43681 atctcgacgc aatgcgggcc ggaactgatc tcgaacggcc gtgacgtgtc actggtgtgg
    43741 atgtcggaca caccgtgcac cacggtgtcc ttgcccagcg tcaccgctcc cgccccgcgt
    43801 ttgatcagcg agaggtggaa cgcctcgggg tccgacctcg ctatcagctt cggtgtgcgc
    43861 tggaaggtca ggggacggca ttccatcgga tagaccgcga tcccgccgag cgagatgacg
    43921 cgctggttca cccagaagtc ggcggcgtgc tcactgcgca tctccatggg cgcatgcgtt
    43981 tccgacatca gggcccgcca gctctcgaaa cggtcggcgg gcgctagttc cgcgctgcgg
    44041 aacgctctct cgggcagcat gatcacgggt ttacaccggc cgtggcggcc cgcgcaacaa
    44101 gagccgggcc ccggggtgcg ggcggcgggg cgactctccg tcaagacact gtgcacgcga
    44161 ggccaatgcg cggtgctcca gggcttggca gagtaggcgc cagagggtcg gtgaggggac
    44221 gggaaaccgg agcccccgcc gacgaccggg gcctctcgct gtcccggcac tgagctgacg
    44281 ccgcccgagg acgggggttt cgggcggcgt cagcccagtg ccgggaacag tccgcctggg
    44341 ccgtttccat cggatcaccc agatgaagat ggccggttga tgcagcgttc gacggtgttc
    44401 cgccccttgt cgaccgcgcg gtcgaaggcg ggtggggcct gccgccacgg cggccgagcc
    44461 gcttacggtt cgtggggggc ttgaccgccg gcagcccggc ccgcgcggga cgggctcatt
    44521 gactgccgcg gatctcgtcg atgcgccgcg ccagggcctc cgtctccgcg atcagccgcg
    44581 catgcgcctt cttctgctcc gcatcgccct ggtccctgaa cgccgcgctg aagtggggtt
    44641 ggagctgggt ccaccagccg tagtccagca tcgcccacgc ctgtgggcag aggggggcgc
    44701 gggttttggg gaggtagccg ctgtcgacca gggatttctg gtagttcttc gggtcgctgc
    44761 cctccaggta gcacaggaag ttgaaggctc gttgctgggt gacggggtgg tcgctcgcca
    44821 ggccttccag ggtcggatgg ccttccttgc gggcgagctc gtcgaagagg accgcggcgg
    44881 ccagggaggg gcccggcccg acctcgttga cggtgtagaa ggacgcgaag ccgtcagccg
    44941 cgtcctcttc gaggccgagg ttggccagga ggagctggcg ttgcagggcg tggcccatct
    45001 cgtggccgaa gatgaactcg gtcgacagca cggtgagatc gtcggtgttg tactcggacg
    45061 cggggagggg ggcaggccgt tcgacggtct tcacgacgtc ggcgagggcc ttttcgatgg
    45121 ccgtcaggaa cgacggcggg acgaaaatcg tcctgccgtc gggttgggtg acggcgtcgg
    45181 tgacgccggg cggcacggcg gcggtgacct tcacgaccat gtcgtgcggg agggtcagag
    45241 atctgttcac ccattcggcc gtccgctcca gcacacggga cttccggatc agcgccacgg
    45301 cctgccggtc ctccggtttg accgtctggg cctcgtagac gacggtgacc ctgccggaac
    45361 gcgccgtctg ggggcgaggt cctgctccgg gcccctgccc ggcgtcgcgg acgccgccgc
    45421 cgcacccggt tacgacgaca ccggcgagta ccagcacgcc tgacaggacg atgcgcgccc
    45481 tcttcgggcg accggcggtg ttcggcatcc ttggtcggct cccgtcgcgt gttcccgcac
    45541 tgatcctccg gccgtccggc gtcgggcgca cgtcgagccg cccgtacggg ggaccgtccg
    45601 gcacggtgcc gacgaacacg aggacccgaa catgcgggcc ggccgcccgg acggcttcca
    45661 catcgtcggg cgccagggcg gtggattgct gtcggaacag ttgcggccgg accctcgatc
    45721 cgatcacggt ctacagatgc cgtagtaggc ggcgacacac agggcgaagg ccctgccgtt
    45781 agcagagggc cgagttggcg gaagagggcg gcgcccctcc taagcctcgc tccgcttagc
    45841 caactggcct gaaccgccgg caacagcccc tttcagtaac tttggtccgg aatttaaggc
    45901 cgcccccctc tagtgcagcc tgtgaaccag ctctacctcg aaggagatcg gggcgcggct
    45961 acgaggcggg tctaacgggg cgcgacggct gacggggtgc gggggctggt cgatctgcca
    46021 gttctcctgg ctggtcgtcg gcggcaggtc ccgtcccctc tgattcggct acgctggtgg
    46081 agctatcgca cgtgaacgaa ggacgcatat ggctcgcccc tacagccccg gaccgaaaca
    46141 gttcgtcttc gctgtgggtg atggcaacga ccaacaggtc tccgtcggtg accctcagga
    46201 agcctatgta gcgttctccg cgttcttccg tgatcgagaa tccgacatct acaccatcaa
    46261 ggatgaatcg tcggagcaga gtttggtact catgcccggt cagggtgtta tttcccgtat
    46321 caaagatgcg gaccaactcc ggtcggaaca ccttcgggtc gaccggggca atcgctacct
    46381 tccgagcgcg atgctgttct tcgagaacgg atattccggc ctcgaccgct tcggccagtg
    46441 gttctccggc ctcaccgacc tcgacgcatc accggagact cgcggtgccg cccgtgccgc
    46501 cacgttcacg acggaagcag aggcgatcga agaagtcgcc cggatctggg cgacttcggg
    46561 ctgcgtggac ccgagcgacc agtactacgt cttcttcgac tcgcatggtg tcgacgatga
    46621 ccgagccgaa cgagccgaac tgctcaagtt gatcgagttc ctcggtatcg aacgagtcga
    46681 cgccccggtc aatgccgccg ggggcgaagt ctgggtgcgc accgacacac gcctcgacgt
    46741 cgaatgtgca cggtggtcgt gagcagatgg tgcggtgtag ggctgcaata tttccgtgat
    46801 gccgggcggt gccgttccgg gggaagactg agtccatgag agagatagtt tttactcgca
    46861 acagcggctg gatcccgaac gtgatccgcg aggacggcga gctgaagctg atgctcggtg
    46921 ccggggctga cgccaaccac gaacctcgca cgttcacgtt ctcgatcagc gaagcccatc
    46981 ttgcggtgat ccgcgaggac ctggccagac acctgctgct gtggagtgcg gtccttcctt
    47041 tgtgcgacga cgccggaacc cggggccggc tcgacgagaa tgctgccgtc gcgctcctgg
    47101 acccgatcct ccttgccacg cccgccgacg ccgacgcact cttccagcgc atccgatggg
    47161 acaggagtcg gctcgtctcc cacggggccg acatcggtct ccttgagcgc ggtcaggtat
    47221 gcgcggcgat gcgcgcggcg acagagacct caaacgggaa acgcgctcag gaataccacg
    47281 cgggccgccg tcgcgccgag cgtggagcag tactcggtcc actcgacgcc gcgattctga
    47341 ggtacacggg ccagtacctg cacggcgcga cggttccgag gcggacgccc gacgcagtcg
    47401 cccccgagct gctgcccgag gtcatgcggg tgatcgccac tgcggagcag gcgtgcgctg
    47461 ggatgcggat cggccgcgat ccgcggcggg gaaaccgcgc cacggacagg cgcgactggg
    47521 atcggatggc gacgacggtc gaagcggccg tgcgccgttc acaccctgag cgcgtcgatg
    47581 aggcggtgcg taccgtgagc ttcctgatgt gctcggaggc cgcggaccgc tccaggcgca
    47641 cacccatgga ggctgccggc caccgcgccg acttcggcgg gagtgcgagg aagacggccc
    47701 tgtcgttcac cgacgacaaa ggcgtcgaga agaagtggct acgggacagt ccccgcaccg
    47761 ccgccgcgga gttctgggag ttcgtcggcg atcgctctgc cgcggacaac gaagtgttca
    47821 ccattgagga cgaggagagg ggcgaaggga tccagctcca cttctacgcg gactccatcg
    47881 cccggatcat gacgctgcgc gagggggaag gcgggtctga tccggagtac cgggtcgagt
    47941 acagcctggt cgacgggatc ggcgggtacc ggaacctggt gagcgccttc gtccgcggcg
    48001 gctacgccgc actcgaacag cacggcccct ggatgtcgga tgtcgccgag ttcgagcgcg
    48061 cgcgtcggcg gcgcgaggcc cggtagtccc agcgggagcc tgcgcactga gcgttgccca
    48121 acggccgcat gacctccaca gccctcgtcc ttactccgcg gggctggtgg cgtgtcaggg
    48181 ccacggcccc ggccgccgct ggtgtcacgg ccttcgctgt gctggccgcc gcacctgtgt
    48241 ccgccggcgc tgcgggtgcc gccgcagagc ggctgacggt cgtccggctg ccgacgggca
    48301 gcagttcccc gtggccagca ccaacctgct cggcgcgaag atcctcttcg aattcgagaa
    48361 ctacgccacc aatgtggtgt gcacggcgac ctcctgtacc ggcacgacgc ccgcaggcaa
    48421 gtacgcctgc cagccacag
//
