LOCUS       NZ_BMVE01000006        29782 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces goshikiensis strain JCM 4640 sequence06, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVE01000006
VERSION     NZ_BMVE01000006.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 522381)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650555.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:30:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,491
            CDSs (total)                      :: 7,410
            Genes (coding)                    :: 7,286
            CDSs (with protein)               :: 7,286
            Genes (RNA)                       :: 81
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 44 of 125
            Pseudo Genes (incomplete)         :: 101 of 125
            Pseudo Genes (internal stop)      :: 9 of 125
            Pseudo Genes (multiple problems)  :: 27 of 125
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 170697
            Orig. end                         :: 200479
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVE01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..29782
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..29782
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29782
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15782](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..15782)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(141..965)
                     /locus_tag="IE248_RS19525"
                     /old_locus_tag="GCM10010336_39450"
     CDS             complement(141..965)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179461.1"
                     /locus_tag="IE248_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39450"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_037793331.1"
                     /transl_table=11
                     /translation="MRALRAGRLTYAVLGVFTLGSLFPLVWTAIAASRNSTRLARTPPP
                     FWFGGNLGRNLSVAWTDANMGTALLNTVIVAGTVAAGTVVFSTLAGFAFARLRFRGSRV
                     LLALVVGTMLIPPQLSVVPLYMLIAELSWTDRLQAVVLPTLVSAFGVFFMRQYLAQALP
                     AELVEAARTDGASSLRIVWHVVFPVARPAMAVLGMLTFVMAWNDFFWPIVALTQNGSPT
                     VQVALTGLGRGYVPDQSVIMAGALLGTLPLLLVFLLFGRQIVGGIMQGAVKG"
     gene            complement(962..1945)
                     /locus_tag="IE248_RS19530"
                     /old_locus_tag="GCM10010336_39460"
     CDS             complement(962..1945)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741569.1"
                     /locus_tag="IE248_RS19530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39460"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_008741569.1"
                     /transl_table=11
                     /translation="MTDETAVLSPSPARTARKGEGEGRRQVWRSRRYRWDVRFGPYAFV
                     APFFLFFAAFGLFPLLYTGWAALHQVELTDPDSMTWVGLKNFTRLWDDEFFWNALRNTV
                     TIGLLSTVPQLLIALGLAHLLNYRLRGSAFFRVAVLTPYATSVAAATLVFVLLFGRDYG
                     MVNWALSGLGFGPVDWQNGPLASQVAVSTIVVWRWTGYNALIYLAAMQAVPAELYESAE
                     LDGASRWRQFLHVTVPSLRPTIFFTCVVSTIGATQLFGEPLLFNGGAAATGGSDHQFQT
                     LGLYLYEQGWVNLHLGRASAIAWAMFLILLLIAGAARLLRGRGEAR"
     gene            complement(1962..3314)
                     /locus_tag="IE248_RS19535"
                     /old_locus_tag="GCM10010336_39470"
     CDS             complement(1962..3314)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741570.1"
                     /locus_tag="IE248_RS19535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39470"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_008741570.1"
                     /transl_table=11
                     /translation="MRASARVQANVRRTLVSAGAAAAAAALLLTGCSSDPADSSERGGR
                     SGGKDGTTTLTVGVFGAFGLQEAGLYDEYTAQNPGIRIEQTSIERNENYYPQLLTHLGT
                     GSGLADIQAVEVNNIAEITATQADKLVDLGKAPGVDRAAYLPWKWAQGTASAAKGGATV
                     GLGTDIGPQGICYRKDLFEAAGLPTDRTAVGALWADDWNKYLEAGKAYKAKAGAGKAFV
                     DSASGVMAAVTGSSAQRFYDEQGKVAYKTNPAVRGAFDLAASFATEGLSAKLQQFTPAW
                     DQGFANGTFATVSCPAWMLGYIQDKAGPAGKDKWDVARAPKPGNWGGSFLVVPKAGKHA
                     EEAAKLAAWLTAPAQQARLFEKRGSFPSASAAYRLPAVSGARHDYFGGAPIGEIFARAA
                     EGVPVTVLGPKDLVIAQNLADIGMLQVDQKGRTPQEGWDAAVKAIDNALDQ"
     misc_feature    complement(3365..3379)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     misc_feature    3366..3380
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     gene            3418..4443
                     /locus_tag="IE248_RS19540"
                     /old_locus_tag="GCM10010336_39480"
     CDS             3418..4443
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741571.1"
                     /locus_tag="IE248_RS19540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39480"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_190031270.1"
                     /transl_table=11
                     /translation="MNGQGRSGGRPTLEEVAVRAGVGRGTVSRVINGSSKVSEHTRAAV
                     EAAVAELGYVPNRAARALAANRTDAIALVIPEPEARFFAEPYFSDVVRGVGATLAETDV
                     QLVLTLAGSDRERRRLAQYLSGHRVDGVLLVSVHAGDPLPELLAELGIPAVISGRRSAD
                     EALPCVDSDNLAGAAEAVHHLLGRGRRAIATITGPLDVYGAQCRLDGYRQALAAAGQPV
                     AEELIAVADFTEEGGRRAMRELLERRPGIDAVFAASDVMAAGARRELRAAGRRIPDDVA
                     LVGFDDSVVARHMDPPLTSVRQPIEEMGRTMARVLLERIAGESPEHSIVLPTELVVRES
                     S"
     tRNA            complement(4546..4618)
                     /anticodon=(pos:complement(175280..175282),aa:His,seq:gtg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IE248_RS19545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10010336_t00530"
                     /product="tRNA-His"
     gene            complement(4546..4618)
                     /locus_tag="IE248_RS19545"
                     /old_locus_tag="GCM10010336_t00530"
     gene            complement(4726..5328)
                     /gene="orn"
                     /locus_tag="IE248_RS19550"
                     /old_locus_tag="GCM10010336_39490"
     CDS             complement(4726..5328)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="orn"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948196.1"
                     /locus_tag="IE248_RS19550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39490"
                     /product="oligoribonuclease"
                     /protein_id="WP_073799370.1"
                     /transl_table=11
                     /translation="MNDRMVWIDCEMTGLSLTDDALIEVAALVTDSELNVLGEGVDIVI
                     RPPDTALETMPDVVRAMHTSSGLLDELAGGTTLADAEAQVLAYVREHVKEPGKAPLCGN
                     SVGTDRGFLLRDMAALEGYLHYRIVDVSSVKELARRWYPRAYFNSPPKNGNHRALADIK
                     ESIAELRYYREAVFVPQPGPDSDTARSIAAKHVVPAE"
     gene            complement(5469..6638)
                     /locus_tag="IE248_RS19555"
                     /old_locus_tag="GCM10010336_39500"
     CDS             complement(5469..6638)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741574.1"
                     /locus_tag="IE248_RS19555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39500"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_008741574.1"
                     /transl_table=11
                     /translation="MSQDSTVVVDAGRKLAGRRRREIVAVLLFSGGPIFESSIPLSVFG
                     IDRQDAGVPRYRLLVCAGEDGPLRTTGGLELTAPYGLEAIARAGTVVVPAWRSITSPPP
                     PEALDALRQAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVDP
                     RELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGSEAAGALARRLVVPPRRTGGQERYLDR
                     SLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWLI
                     TQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRSAYRARRPQT
                     DTAQVSDISSGPLPHQRTPQPQRAAAALAAAGPTVTELYAPGRVLREHA"
     misc_feature    complement(6976..6990)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.48"
                     /tool="antismash"
     gene            complement(7015..7470)
                     /locus_tag="IE248_RS19560"
                     /old_locus_tag="GCM10010336_39510"
     CDS             complement(7015..7470)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741575.1"
                     /locus_tag="IE248_RS19560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39510"
                     /product="hypothetical protein"
                     /protein_id="WP_190031271.1"
                     /transl_table=11
                     /translation="MPGYPVHPVQPAQPARSVRAAHPFPPSALHPSVRPARRSHDDPAG
                     DVVRWAAFSCLLVPVVLVVYGTSFGGTVGATLGLAAVTAACRVLLRHSEKMERATAARA
                     FARGRQPGRAAPTHRGRHSRGGAGSHRGCAAYEWIPGVVPGTPPPQD"
     gene            7826..8356
                     /locus_tag="IE248_RS19565"
                     /old_locus_tag="GCM10010336_39520"
     CDS             7826..8356
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325548.1"
                     /locus_tag="IE248_RS19565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39520"
                     /product="universal stress protein"
                     /protein_id="WP_008741576.1"
                     /transl_table=11
                     /translation="MAGHEFSEPADRKRKPVADHTSSDLRAVEQARHPCDPAFRHGVVV
                     GFDGSTSSERALAYAIGMARRSGSGLIIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVL
                     GLELACADYLSEVPWILVERGGDICHELEEVGREYSADAIVVGSTHGIVGRIFGSVAGR
                     LAKRAQRPVVVIP"
     gene            8456..9025
                     /locus_tag="IE248_RS19570"
                     /old_locus_tag="GCM10010336_39530"
     CDS             8456..9025
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741577.1"
                     /locus_tag="IE248_RS19570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39530"
                     /product="GPR1/FUN34/YaaH family transporter"
                     /protein_id="WP_100582581.1"
                     /transl_table=11
                     /translation="MDNGVSAGSTASTSTLGNIALGLTLLAFGIGHTGVINGVSAADSV
                     SLATYLGGLALFVLGVLEFRAGNGFNGTAFAGLGAFWFTWANGADGKVSADAAGLFLVL
                     FALLGLTLTTGAPRGPFGQGVYALFTLSLLLLAIGAFADSGALGKAAGWVAVVGGLLAW
                     YGATAVVAGWPAAFGRGSRRAVVTAS"
     gene            complement(9105..10922)
                     /gene="glmS"
                     /locus_tag="IE248_RS19575"
                     /old_locus_tag="GCM10010336_39540"
     CDS             complement(9105..10922)
                     /EC_number="2.6.1.16"
                     /GO_function="GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA]"
                     /GO_process="GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980526.1"
                     /locus_tag="IE248_RS19575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39540"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="WP_073799372.1"
                     /sec_met_domain="GATase_7 (E-value: 1.7e-16, bitscore:
                     55.1, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGKRDVAPLLLEGLQRLEYRGYDSAGIVVNTPKSPALK
                     VVKAKGRVRELESRVPKRFAGTTGIAHTRWATHGAPSDINSHPHLDADNNVAVVHNGIV
                     DNADELRAKLVADGIVFISETDTEVITHLIARSQADTLEEKVREAVKVIEGTYGIAVMH
                     ADFPDRIVVARNGSPVVLGIGEKEMFVASDVAALVAHTRQIVTLNDGEMATLKADDFRT
                     YTTSGATTTATPETVEWEAASYDMGGHDTYMHKEISEQADAVDRVLRGRIDDRFNTVHL
                     GGLNLDPREARGIRRVKILGCGTSYHAGMIGAGLIESLARIPADAEPASEFRYRNPVVD
                     PDTLYIAVSQSGETYDVLAAVQELKRKGARVLGVVNVVGSAIAREADGGVYVHAGPEVC
                     VVSTKCFTNTVVAFALLAVHLGRIRDLSVTDGKRIIEGLRKLPAQIQEILETEEDIKKL
                     AAEYAEAKSMMFIGRVRGYPVALEASLKLKEISYIHAEAYPASELKHGPLALIEPAMPT
                     VAIVPDDDLLEKNRAALEEIKARSGRILAVAHREQEKADHTILVPKNEDELDPILMGIP
                     LQLLAYHTALALGRDIDKPRNLAKSVTVE"
     misc_feature    10881..10891
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(11022..11297)
                     /locus_tag="IE248_RS19580"
                     /old_locus_tag="GCM10010336_39550"
     CDS             complement(11022..11297)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608703.1"
                     /locus_tag="IE248_RS19580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39550"
                     /product="hypothetical protein"
                     /protein_id="WP_008741579.1"
                     /transl_table=11
                     /translation="MLDRRPSHDDLVDHLVRSTALQRGEAARVVLDVLAYFDETTEEFV
                     RRRHRELQSGGAVNAEIFERIAAELPHRAVAPPELSLRQLRRVVYG"
     misc_feature    complement(11248..11263)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.91"
                     /tool="antismash"
     misc_feature    complement(11371..11388)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.29"
                     /tool="antismash"
     gene            complement(11405..12289)
                     /locus_tag="IE248_RS19585"
                     /old_locus_tag="GCM10010336_39560"
     CDS             complement(11405..12289)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976013.1"
                     /locus_tag="IE248_RS19585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39560"
                     /product="DUF4429 domain-containing protein"
                     /protein_id="WP_037797611.1"
                     /transl_table=11
                     /translation="MAEIIQKDGTWTFDGDVVRIVPGRDKEVGPLRQTLGELAVPLRAI
                     AGVSYEPGRRSGRLRLRLRDGADPLLQVTGGRLPESSDPYRLTVEQDRTGVAEYFVDEV
                     RNALLLEQVDPGPVDAYLLPGPAVPVTAGGGDAAVAFDGDRVSLDWNWTAEDAKHSAGP
                     SRFRVADVRAVDWSPAKGLTNGWLRFSLAGAPAAAAPKYDPHAVELFGFGKKELVTALV
                     AAAVAVRLPHPAAPAALPERAAPAAGALAGEAAAEDHDALLRRLQELGDLRAKGILTDE
                     EFAETKALILRRF"
     misc_feature    12274..12288
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.71"
                     /tool="antismash"
     gene            12342..13934
                     /locus_tag="IE248_RS19590"
                     /old_locus_tag="GCM10010336_39570"
     CDS             12342..13934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542185.1"
                     /locus_tag="IE248_RS19590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39570"
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="WP_190031272.1"
                     /transl_table=11
                     /translation="MRVLRRALGTLLALGAAVSCTAAHGDDARPGGDRPAALTPYERLL
                     PAPASARPGGPGYPFGAGTVIRTGRAGGAAGAEVRRVGELLAGQLRGPSGLPLPVVDGE
                     AGDGVRLRLDGRAAGLGPEGYRLEASASGVTLTARTPAGLFHAGQTLRQLLPVSGPGTV
                     PGGTVTDAPRFAYRGAMLDVARHFFGIDQVKRYVDQLAQYKVNTLHLHLTDDQGWRIAV
                     DGWPRLAEYGGAGEVGGGPGGYWTKDEYRELVAYARERYVEVVPEIDMPGHVNAAQASY
                     AELNCDGKARERYTGTKVGFSSLCVGKERTYEFIDDVLGELAELTPGRYLHIGGDEAHS
                     TPAADYAAFMDRAQQVVARHGKTVLAWHQLATARPAAGAVLQYWGHDKTPAAEKAAVAA
                     AARAGHPVILSPADRLYLDMKYDTATKPGLAWAGYVPVRRAYDWNPGAYLEGVAESAVL
                     GVEAPLWTETISARADLEYMAFPRVLGLAELGWSPAGALDWTAYRQRLAAQAPRLTAQG
                     IAFHRAPDVPWGR"
     gene            complement(14001..15782)
                     /locus_tag="IE248_RS19595"
                     /old_locus_tag="GCM10010336_39580"
     CDS             complement(14001..15782)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741581.1"
                     /locus_tag="IE248_RS19595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39580"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_190031273.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.9e-78, bitscore:
                     257.6, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLTDAISHLSPELWDRANRALVRKGLAEFSHERLLTPKPLGGSS
                     YSVRSDDGTVEYRFEAQLHALDHWAVDEASITRHRDGAELPLDALDFHIELREALGLSP
                     EVLPVYLEEISSTLAGSGYKYTKPQVSSAVLAKSSFQDIETGMTEGHPCFVANNGRLGF
                     GVHEYLSYAPETANPVHLVWVAARKDVSTFTAGAGMDYDSFVREELGEGTIAAFSARMA
                     ELGLDLADYHLLPVHPWQWWNKTTVTFAAEIANRRLVLLGEGSDAYLAQQSIRTFFNTS
                     APEKHYVKTAISVLNMGFMRGLSAAYMEATPAINDWLHQLIEGDEVLRSVDFSIIRERA
                     AIGYHHRQYERATDRYSPYRKMLAALWRESPVASLRGGERLATMASLLHVDSEGKSFVG
                     ALIAESGLTPEEWLRSYLKAYLVPLLHCFYQYDLAYMPHGENTILVIEGGVVKRAIFKD
                     IAEEIVVMDPDAVLPPAVERVRADIPEDMKLLSIFTDVFDCFFRFLGSILVSEGICEED
                     TFWKAVADCGHAYQESMPQLAERFERYDYFAEEFQLSCLNRLQLRNNKQMVDLADPAAA
                     LQLIGTLKNPVAPFARR"
     gene            complement(15779..16363)
                     /locus_tag="IE248_RS19600"
                     /old_locus_tag="GCM10010336_39590"
     CDS             complement(15779..16363)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741582.1"
                     /locus_tag="IE248_RS19600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39590"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_100582577.1"
                     /transl_table=11
                     /translation="MSTTEILYARTDAELGTFSVRPLDPFADAELLHGWVTHPKASFWM
                     MQDATLPDVEREYMRIAAHEHHQAFIGLHEGRPAFLMETYDPSELELVGLYDAQPGDVG
                     MHFLVAPSDTPLHGFTRAVITTVMAAVFADPAAERVVVEPDVNNTAVHALNEAVGFVAE
                     RPVTKPEKEALLSFCTRAQFEAATGLTGESI"
     gene            complement(16360..17661)
                     /locus_tag="IE248_RS19605"
                     /old_locus_tag="GCM10010336_39600"
     CDS             complement(16360..17661)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741583.1"
                     /locus_tag="IE248_RS19605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39600"
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_100582576.1"
                     /transl_table=11
                     /translation="MPSTVKPHDFIGIGLGPFNLGLACLTDPIDELDGLFIESKPHFEW
                     HAGMFLDGAHLQTPFMSDLVTLADPTSPFSFLNYLKDQDRLYSFYIRENFYPLRAEYND
                     YCRWAADRLDNVLWSTSVSEVTYDEAAGLYEVRTDKGETHLARRLVLGTGTSPYVPQAC
                     ANLGGDFLHNSSYMQNKEELQKKKSITLIGSGQSAAEIYYDLLAEIDVHGYQLNWVTRS
                     PRFFPLEYTKLTLEMTSPEYVDYFHALPEETRYRLETQQKNLFKGIDGDLINEIFDLLY
                     QKKVSMPGPVPTTLLTNTSLNTTAYDTTTGTYALGLRQEEQERDFSLATEGLVLATGYK
                     YVVPEFLNPVRPRLNFDGHGRLDAARNYSVDTTGQGVYLQNGTTHNHSITSPDLGMAAY
                     RNAYIVGELLGREYYKVEKSIAFQQFAAPEGMHA"
     gene            complement(17645..19144)
                     /locus_tag="IE248_RS19610"
                     /old_locus_tag="GCM10010336_39610"
     CDS             complement(17645..19144)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741584.1"
                     /locus_tag="IE248_RS19610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39610"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_190031274.1"
                     /transl_table=11
                     /translation="MRSHLLNETTADIYRRTVTEGVARVAAKLATTERPHTGISVDELA
                     PVINGIDLDRPLEDPAAVLDELEDVYLRDAVYFHHPRYLGHLNCPVVIPAVLGEAVLSA
                     VNSSLDTWDQSIGGTLIERRLIDWTAQRIGLGEGADGVFTSGGSQSNFHALLLARDEAC
                     RIVMKQALNEGRELPKSEVLPKLRIFTSEASHFSVKKSAAMLGLGYEAVISVPVDRNRR
                     MDTAILALELENCRRDGLFPMAVVATAGTTDFGSIDPLPEIARLTSEHSAWMHVDAAYG
                     CGLLISPTRRHLLDGIENADSVTVDYHKSFFQPVSSSAVLVRDRDTLKHATYHADYLNP
                     RRMAEERIPNQVDKSIQTTRRFDALKLWMTLRTMGADGLGSLFDEVIDLAAAGWDIIDA
                     DPRFEVVVKPQISTLVFRYVPGPDSADLPAELLDEAQLHARKALFASGEAVVAGTKVDG
                     KQYLKFTLLNPQTTTADISAVLDLLAAHAAQFLGESLAVHR"
     misc_feature    19187..19205
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.39"
                     /tool="antismash"
     misc_feature    complement(19192..19210)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 34.36"
                     /tool="antismash"
     misc_feature    complement(19202..19217)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.55"
                     /tool="antismash"
     gene            complement(19327..20235)
                     /locus_tag="IE248_RS19615"
                     /old_locus_tag="GCM10010336_39620"
     CDS             complement(19327..20235)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007264178.1"
                     /locus_tag="IE248_RS19615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39620"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_100582575.1"
                     /transl_table=11
                     /translation="MTVTASDTAPAIAHFRFFELEVLRTRRLGHSFLRVTFGGGSLADF
                     RSGGCDQSLSLFLPPAHEEHTVLPSTDEDTWFGAWRAMPDADRPVMRSYTVREQRRTPE
                     GADEVDIDFVLHGDASPASRWASGAVAGRRILAIGPAVAENKSVRFQPPAATDALLMYA
                     DETALPAAAAILDRLASGTRVRAWFEVPHEDDRLALPTLADAEITWIVREGGAGREERV
                     QRVLDAMRVAELPEAEAPYVWLAGEAGTIRAVRRHIVQERSIDRRAVRFTGYWRLGASE
                     EELLAEAYAGKSASEDPASAL"
     gene            complement(20286..21335)
                     /locus_tag="IE248_RS19620"
                     /old_locus_tag="GCM10010336_39630"
     CDS             complement(20286..21335)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741587.1"
                     /locus_tag="IE248_RS19620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39630"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_073773580.1"
                     /transl_table=11
                     /translation="MPKSRTSYLSRRGLIAAGGALGLVAALSACGGTDSAKGETGKDKD
                     KGAAASGPWTFKDDLGKDISLKAAPKNIVAYTGTAAALYDYGVQVKGVFGPTKTADGKP
                     DVQAGSMDISKVEILGNVYDEFNVEKYAALQPELLVTNTWDGTYWYVPEASKDKILKLA
                     PAAAIGVGGDASLDKSLERTADLAKSLGADLNSKKTADAKARFEAAAAKVREATKANPG
                     IKVLVGSGSADLFYVSTPKTSADLKYFETLGVEFITPDKDKLDAGGFFESLSWENAGKY
                     KADLVLLDNRTGTLQSQELKAKPTWAEMPAVKAGQVAPRVTEPIYSYEKCAQILEDLAK
                     AIQNAKKVS"
     misc_feature    complement(21386..21404)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 27.77"
                     /tool="antismash"
     misc_feature    21408..21419
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            complement(21477..22637)
                     /locus_tag="IE248_RS19625"
                     /old_locus_tag="GCM10010336_39640"
     CDS             complement(21477..22637)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741588.1"
                     /locus_tag="IE248_RS19625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39640"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_008741588.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.5e-39, bitscore:
                     130.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.1e-22, bitscore:
                     75.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.9e-51, bitscore:
                     166.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLDHRLTPEHEELRRTVEEFAHDVVAPKIGDLYERHEFPYEIVR
                     EMGRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPLHLFG
                     TEEQKREWLPRMCSGEILGAFGLTEPDGGSDAGGTRTTAVKDGDEWVINGSKCFITNSG
                     TDITGLVTVTAVTGRKADGRPEISSIIVPSGTPGFTVAAPYSKVGWNSSDTRELSFQDV
                     RVPLANLVGAEGRGYAQFLRILDEGRIAISALATGLAQGCVDESVKYAKERKAFGRPIG
                     DNQAIQFKLADMEMRAHMARIGWRDAASRLVAGEPFKKEAAIAKLYSSTVAVDNARDAT
                     QIHGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGFSS"
     gene            complement(22645..23565)
                     /locus_tag="IE248_RS19630"
                     /old_locus_tag="GCM10010336_39650"
     CDS             complement(22645..23565)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105732.1"
                     /locus_tag="IE248_RS19630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39650"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_073799380.1"
                     /sec_met_domain="HMGL-like (E-value: 2.1e-46, bitscore:
                     153.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPAPALPARVRIHEVGARDGLQNEKSAVPTQVKAEFVHRLAAA
                     GLTTIEATSFVHPKWVPQLADAEELFPQLSDLPGVHLPVLVPNERGLDRALALGATRIA
                     VFGSATETFASRNLNRTVAESLAMFEPVVARAKEGGAHVRGYLSMCFGDPWEGPVPVRQ
                     VVRVAKALLDLGCDELSLGDTIGVATPGHVRALLGELGEEGVGADLIGVHFHDTYGQAL
                     SNTLAALQHGVTTVDASAGGLGGCPYAKSATGNLATEDLVWMLDGLGIETGVDLAALTA
                     TSVWMAEQLGRPSPSRTVRALSHKE"
     gene            complement(23577..25607)
                     /locus_tag="IE248_RS19635"
                     /old_locus_tag="GCM10010336_39660"
     CDS             complement(23577..25607)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741590.1"
                     /locus_tag="IE248_RS19635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39660"
                     /product="acetyl/propionyl/methylcrotonyl-CoA carboxylase
                     subunit alpha"
                     /protein_id="WP_190031275.1"
                     /sec_met_domain="ATP-grasp (E-value: 1.5e-06, bitscore:
                     22.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.2e-07,
                     bitscore: 24.9, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSTVLVANRGEIAVRVIRTLRELGVRSVAVFSDADADARHVREA
                     DTAVRIGPAAAAESYLSVERLLDAARRSGAEAIHPGYGFLAENAGFAQACAEAGLAFIG
                     PPAKAISLMGDKIRAKETVKAAGVPVVPGSSGSGLSDAELVAAAEEIGMPVLLKPSAGG
                     GGKGMRLVRDAGLLAEEIAAARREARSSFGDDTLLVERWVDRPRHIEIQVLADSYGNVV
                     HLGERECSLQRRHQKVIEEAPSVLLTPELRASMGAAAVEAARSCGYVGAGTVEFIVPGG
                     DPSSYYFMEMNTRLQVEHPVTELITGLDLVEQQLRVASGAELGFGQADVTLTGHAVEAR
                     VCAEDPARGFLPSGGTVLALSEPSGGSVRTDSGLVAGVDTGSTYDPMLSKVIAYGPDRA
                     TALRILRGALADTVILGVQTNTGFLRRLLAHPDVVSGNLDTGLVERDLSTLLPEGVPPE
                     VFAAAALLAAHRPALPSPSGNWVDPFGAGDGWRLGGTPAWTVHHFRLPGQEPVSVRSRP
                     SGAETELLLAEDSGAPARGRIVSRGEDRVTVELDGVTHTFSHARSPEGTWLGRDGDSWH
                     VQAHDPVTAALSGRGHAGAETLAAPMPGTVTVVKVAVGDKVTAGQSLLVVEAMKMEHVI
                     SAPHSGTVAELDVSPGTTVAMDQVLAVVTPDEPRGEEEEGK"
     gene            complement(25624..27240)
                     /locus_tag="IE248_RS19640"
                     /old_locus_tag="GCM10010336_39670"
     CDS             complement(25624..27240)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577260.1"
                     /locus_tag="IE248_RS19640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39670"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_008741591.1"
                     /transl_table=11
                     /translation="MQQAPVLTSAADPASEAWRTNEAAHRELTEGLRARLGAARLGGGD
                     KARARHTARGKLLPRDRVDALLDPGSPFLELAPLAAEGMYGGAAPAAGVIAGIGRVSGR
                     ECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQDEVFPDR
                     DHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRGQGTIFLGGPPLV
                     KAATGEVVTAEELGGGEVHSRTSGVTDHLAEDDAHALRIVRNIVATLPGRGELPWSVEA
                     PEEPKVDPAGLYGAVPVDSRTPYDAREIIARLVDGSRFQEFKAEFGTTLVTGFARIHGH
                     PVGIVANNGILFSESAQKGAHFIELCDQRGIPLLFLQNISGFMVGRDYEAGGIAKHGAK
                     MVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLA
                     TVKRDQIEGAGQEWPADDEEAFKAPVRAQYEEQGNAYYATARLWDDGVIDPMETRQVLG
                     LALTACANAPLGDRGFGIFRM"
     gene            27340..27918
                     /locus_tag="IE248_RS19645"
                     /old_locus_tag="GCM10010336_39680"
     CDS             27340..27918
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741592.1"
                     /locus_tag="IE248_RS19645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39680"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_008741592.1"
                     /transl_table=11
                     /translation="MSTSAAAPTRREQILSEAARLFAERGFHGVGVDEIGAAVGISGPG
                     LYRHFAGKDAMLAELLVGISERLLTGGRRRAEEAAGDPSLVLASLIDGHIDFALDDRAL
                     ITVHDRELDRLRDADRKLVRQLQRQYVELWVAVVRELHPRVGEAEVRVSVHAVFGLLNS
                     TPHLAALGREATESLLRRLAHGSFGALSG"
     gene            27975..28781
                     /locus_tag="IE248_RS19650"
                     /old_locus_tag="GCM10010336_39690"
     CDS             27975..28781
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007264171.1"
                     /locus_tag="IE248_RS19650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39690"
                     /product="phosphatase"
                     /protein_id="WP_100582573.1"
                     /transl_table=11
                     /translation="MGRMPMPIETSVPTRAELIDHLVRTRIAGDVATPRENNLSHYRKL
                     ANGDRHYWLGLELGDRWADEQDVLAVMAERCGVVDDPQHRQGQDTIDPELTVAGLERLA
                     ARLRKAALDRQSVLLATGHPGGLLDVHRATAVALRAAGCEIVVIPAGLTADEGSVWQFA
                     DIAVLERGATLWHTHSPAPMAAILDGLAAAGRPQPDLVVADHGWAGCAAQRGLDAVGYA
                     DCNDPALFLGEAEGTLQVAVPLDDHVRDPRYYDPMVAYLLATAGLL"
     gene            complement(28825..29703)
                     /locus_tag="IE248_RS19655"
                     /old_locus_tag="GCM10010336_39700"
     CDS             complement(28825..29703)
                     /NRPS_PKS="Domain: PKS_KR (16-178). E-value: 9.9e-13.
                     Score: 40.3. Matches aSDomain:
                     nrpspksdomains_IE248_RS19655_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268084.1"
                     /locus_tag="IE248_RS19655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_39700"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_229895410.1"
                     /sec_met_domain="adh_short (E-value: 2e-30, bitscore:
                     100.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCVCTHKSRETSMSTKTVLITGTSSGIGLAAAVAAAQAGWHTVAT
                     MRDTAKADALREAAAEAGVADLVQVKRLDVTDAGSVASCVAEVVAERGGLDAVVNNAGA
                     GFVGTIEQHGMEGVRSTMEVNYFGVVELTKAALPHLRASGGRVITVTSVGGMIGQPFNE
                     SYCAAKFAVEGFMESLAPVAATTGVQVAVVEPGAVASEFVTNVRLDVPALLAEAGPYAP
                     ALKAYIERTMQSFGNAQTSQEAAAPIIAALTAETMPFRIQTSDWAREFVATKLADLDGS
                     AVQDLTGGWLR"
     aSDomain        complement(29170..29655)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS19655_PKS_KR.1"
                     /evalue="9.90E-13"
                     /label="IE248_RS19655_PKS_KR.1"
                     /locus_tag="IE248_RS19655"
                     /protein_end="178"
                     /protein_start="16"
                     /score="40.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVLITGTSSGIGLAAAVAAAQAGWHTVATMRDTAKADALREAAAE
                     AGVADLVQVKRLDVTDAGSVASCVAEVVAERGGLDAVVNNAGAGFVGTIEQHGMEGVRS
                     TMEVNYFGVVELTKAALPHLRASGGRVITVTSVGGMIGQPFNESYCAAKFAVEGFMES"
ORIGIN
        1 ggtgtccccg ccgtgcacct tgcccggcgt acggcagaag gtgtcccaga tgcagggccc
       61 gcggccggcc gccgcgccct cgatctggaa ggccgccgtg gccgtgcccc agaggaaccc
      121 ctccgggaat gtcctgtccg tcatcccttg accgccccct gcatgatgcc gcccacgatc
      181 tggcggccga agagaaggaa caccagcagc agcgggagcg tgcccagcag cgcgcccgcc
      241 atgatcaccg actggtcggg gacgtagccc cggcccagcc ccgtcagggc cacctgcacc
      301 gtcgggctgc cgttctgggt cagcgcgacg atcggccaga agaagtcgtt ccaggccatg
      361 acgaacgtca gcatcccgag caccgccatc gcgggccggg ccaccgggaa gacgacgtgc
      421 cacacgatcc gcagcgaact cgccccgtcc gtccgcgccg cctccaccag ctccgccggc
      481 agggcctgcg ccaggtactg ccgcatgaag aacaccccga aggccgagac cagcgtcggc
      541 aggaccaccg cctggagccg gtccgtccac gacagttcgg cgatcagcat gtacagcggg
      601 accacgctca gctgcggggg gatcagcatc gtccccacca ccagcgccag cagcacccgg
      661 ctgccccgga accgcagccg ggcgaacgcg aacccggcca gcgtcgagaa caccaccgtg
      721 ccggccgcga cggtgcccgc cacgatcacg gtgttcagca gggccgtgcc catgttcgcg
      781 tcggtccagg cgaccgacag gttgcgcccc aggttcccgc cgaaccagaa cggcggcggc
      841 gtccgggcga gccgcgtgct gttccgcgac gccgcgatcg ccgtccacac cagcgggaag
      901 agcgacccga gggtgaacac cccgaggacc gcgtacgtca gcctccccgc gcgcagcgcc
      961 ctcatcgcgc ctccccccgc ccccgcagca gccgggcggc gcccgcgatc agcagcagga
     1021 tcaggaacat cgcccaggcg atcgccgagg cccgccccag gtgcaggttc acccagccct
     1081 gctcgtacag gtacagcccg agcgtctgga actggtggtc ggagccgccc gtcgcggccg
     1141 ccccgccgtt gaacagcagc ggctcgccga acagctgggt cgccccgatc gtcgagacca
     1201 cacaggtgaa gaagatcgtc ggccggagcg agggcaccgt cacgtggagg aactgccgcc
     1261 accgcgaggc cccgtccagc tccgcggact cgtacagctc cgcgggcacg gcctgcatgg
     1321 ccgccaggta gatcagcgcg ttgtagccgg tccaccgcca caccacgatc gtcgacaccg
     1381 ccacctgcga ggccagcggg ccgttctgcc agtccaccgg cccgaacccg agcccggaca
     1441 gcgcccagtt gaccatcccg tagtcccggc cgaagagcag gacgaagacg agcgtggccg
     1501 ccgccaccga ggtcgcgtac ggggtgagca ccgcgacccg gaagaaggcg gagccccgca
     1561 gccggtagtt cagcaggtgc gccagcccca gcgcgatcag cagctgcggc accgtggaca
     1621 gcagcccgat ggtgacggtg ttccgcagtg cgttccagaa gaactcgtcg tcccacagcc
     1681 gggtgaagtt cttcagcccc acccacgtca tcgaatccgg atcggtcagc tccacctggt
     1741 gcagcgccgc ccagcccgtg tacagcagcg ggaacagccc gaaggcggcg aagaacagga
     1801 agaagggcgc cacgaaggcg tacggaccga agcgcacgtc ccaccggtag cggcgcgagc
     1861 gccacacctg gcgcctgccc tccccctcgc ccttccgcgc cgtgcgggcg ggcgaggggg
     1921 acaggacggc cgtctcgtca gtcatccgcg agcaccggcc ctcactggtc cagggcgttg
     1981 tcgatcgcct tcaccgcggc gtcccagccc tcctgcggcg tccggccctt ctggtcgacc
     2041 tggagcatcc cgatgtccgc caggttctgc gcgatcacca ggtccttcgg gccgagcacc
     2101 gtcaccggca cgccctcggc ggcccgcgcg aagatctccc cgatcggggc gccgccgaag
     2161 tagtcgtgcc tggcccccga gaccgccggc agccggtacg ccgcgctcgc gctcgggaag
     2221 ctcccgcgct tctcgaacag cctggcctgc tgcgccgggg ccgtcagcca ggccgccagc
     2281 ttcgccgcct cctcggcgtg cttgcccgcc ttgggcacca ccaggaagga gccgccccag
     2341 ttgcccggct tcggcgcccg cgccacgtcc cacttgtcct tgcccgccgg gcccgccttg
     2401 tcctggatgt agccgagcat ccaggccggg caggagaccg tcgcgaacgt cccgttggcg
     2461 aagccctggt cccaggccgg ggtgaactgc tggagcttcg cgctcaggcc ctcggtggcg
     2521 aaggaggccg ccaggtcgaa ggcgccgcgc accgccgggt tggtcttgta ggcgaccttg
     2581 ccctgctcgt cgtagaagcg ctgtgcgctg ctgccggtga cggccgccat cacgcccgag
     2641 gcggagtcca cgaaggcctt ccccgctccg gccttcgcct tgtaggcctt gcccgcctcc
     2701 aggtacttgt tccagtcgtc cgcccacagc gcgccgaccg ccgtccggtc cgtgggcagc
     2761 ccggccgcct cgaacaggtc cttgcggtag cagatcccct gcgggcctat gtcggtgccg
     2821 agtccgaccg tcgcgccgcc cttcgccgcg ctcgccgtgc cctgggccca cttccacggc
     2881 aggtacgcgg cccggtccac gccgggggcc ttgccgaggt cgaccagctt gtccgcctgg
     2941 gtggcggtga tctccgcgat gttgttgacc tcgacggcct ggatgtcggc gagcccgctg
     3001 ccggtgccca ggtgggtcag gagctgcggg tagtagttct cgttccgctc gatggaggtc
     3061 tgctcgatgc ggatgccggg gttctgcgcc gtgtactcgt cgtagaggcc ggcctcctgg
     3121 aggccgaagg ccccgaagac gccgacggtg agggtggtgg tcccgtcctt gccgccgctc
     3181 cggccgcccc gctcggagga gtcggccggg tccgacgagc acccggtgag cagcagggcc
     3241 gccgcggccg ccgcggctcc cgcgctgacg agggttcttc ggacgttcgc ctggactcgg
     3301 gcgctggctc gcatgggcat cctccctgaa aggacggaac gtgccgggtg tcgtgtgaca
     3361 cagtgtggga gcgctcccat tggcgtcaag aggtagattc gcacccggga ggaagtcatg
     3421 aacgggcaag ggcgcagcgg gggacggccg accctggagg aggtggcggt ccgggcggga
     3481 gtcggacgcg gcaccgtctc ccgggtgatc aacgggtcgt ccaaggtcag cgagcacacc
     3541 agggccgccg tcgaggccgc cgtcgccgag ctcgggtacg tgcccaaccg cgccgcccgc
     3601 gccctcgcgg ccaaccgcac cgacgccatc gccctcgtca tccccgagcc cgaggcgcgc
     3661 ttcttcgccg agccctactt ctcggacgtg gtccggggcg tcggcgccac cctcgccgag
     3721 accgacgtcc agctcgtcct caccctggcg ggcagcgacc gcgagcgccg ccgcctcgcc
     3781 cagtacctct ccgggcaccg cgtcgacggc gtcctgctgg tctccgtaca cgccggggac
     3841 ccgctgccgg agctgctggc cgagctcggc atccccgccg tgatcagcgg ccgccgctcc
     3901 gccgacgagg cgctgccctg cgtggactcc gacaacctgg cgggcgccgc cgaggccgta
     3961 caccacctcc tgggccgggg ccggcgcgcc atcgccacga tcaccggccc gctggacgtc
     4021 tacggggccc agtgccgcct ggacggctac cggcaggccc tcgccgccgc cgggcagccc
     4081 gtggccgagg agctgatcgc cgtcgcggac ttcaccgagg agggcggccg gcgggccatg
     4141 cgcgagctgc tggagcgccg ccccgggatc gacgcggtgt tcgccgcctc cgacgtgatg
     4201 gcggcgggcg cccgccgcga gctgcgcgcg gccggccgcc ggataccgga cgacgtggcg
     4261 ctcgtcggct tcgacgactc ggtggtggcc cggcacatgg acccgccgct gaccagcgtc
     4321 cgccagccga tcgaggagat gggccgcacc atggcccggg tgctgctgga gcggatcgcg
     4381 ggggagtccc cggagcactc gatcgtgctc ccgaccgagc tggtggtccg ggagtcctcg
     4441 taggtccacc cggcccggta cgcgcggggc ccccggtacg cgcgggaggc ccgggtacac
     4501 gcagaaggcc ccggtccgct ttcgcgggcc ggggccttct cgcagggtga gtgacgggac
     4561 ttgaacccgc ggccacctgg accacaacca ggtgctctac caactgagct acacccacca
     4621 tgtccggtcg gaaaaccgac cggccgaaga aaagggtaca gggtccggga gggtgctcgc
     4681 tccccccttt ccccgcgccc ctctccgcgc tgtcggaagg gggtcctact cggcgggcac
     4741 cacgtgcttc gcggcgatgc tccgcgcggt gtccgagtcc ggaccgggct gcggtacgaa
     4801 gacggcctcc cggtagtagc gcagctcggc gatggactcc ttgatgtccg cgagcgcccg
     4861 gtggttgccg ttcttcggcg ggctgttgaa gtacgcccgc gggtaccagc ggcgggccag
     4921 ctccttgacc gaggacacgt ccacgatccg gtagtgcagg tacccctcca gcgccgccat
     4981 gtcgcgcagc aggaagccgc ggtcggtgcc gaccgagttc ccgcacagcg gggccttgcc
     5041 gggctccttc acgtgttccc gtacgtacgc caggacctgc gcctcggcat ccgcgagggt
     5101 ggtcccgccg gccagctcgt cgagcaggcc ggaggaggtg tgcatcgcgc gcaccacgtc
     5161 gggcatggtt tccagggccg tgtccggcgg gcggatcacg atgtccacgc cttcgccgag
     5221 cacgttgagc tccgagtcgg tgaccagtgc ggccacctcg ataagtgcgt cgtccgtcaa
     5281 cgagagcccg gtcatctcgc agtcgatcca caccatgcga tcgttcatgc gtcccacctt
     5341 atgcggtacc tcgcggatcg tggcgggccc gcggcgcgat caggggggtc cgtccccgca
     5401 cgcgaaggtc cccccaccgg agacggccga tggggggacc tcgcgtcggg cggtgcccgt
     5461 ggcgggcgtt acgcgtgctc gcgcagcacc cggcccgggg cgtacagctc cgtcaccgtg
     5521 ggaccggcgg cggccagggc cgccgcggcc cgctggggct gcggagtgcg ctggtgcgga
     5581 agcggacccg acgagatgtc cgaaacctgc gccgtgtcgg tctgcggccg gcgcgcccgg
     5641 taggcggagc ggtaggcggc cggggaggac cccagctgcc gccggaagtg cccgcgcagc
     5701 gcgaccggcg agcggaaccc gcagcgtccg gcgacctcgt cgaccgagta gtcggaggtc
     5761 tccagcagcc gctgtgcctg gagcacccgc tgggtgatca gccactggag cggcgcgctg
     5821 ccggtcagcg agcggaaccg ccggtcgaag gtgcgcctgc tcatgtaggc gcgggccgcc
     5881 agcgtctcca cgtcgaactg ctcgtggagg tgttccagcg cccaggcgac gacctcggcc
     5941 agcgggtcgg cgccgatctc ctccggcagc gaccggtcga ggtagcgctc ctggccgccc
     6001 gtgcggcgcg gcggcacgac cagccggcgg gccagggctc cggccgcctc gctgccgtgg
     6061 tccgtgcgca cgatgtgcag gcacaggtcg attccggccg cggtgcccgc ggacgtcagc
     6121 acgtcgccgt cgtcgacgaa cagctcgcgc ggatcgacat ggacggacgg gtaccgcttg
     6181 gccagcgtcg gcgcgtacat ccagtgcgtc gtcgcgggcc gcccgtccag cagaccggcg
     6241 gcggcgagca cgaaggcccc cgtgcacagt ccgacgatcc gggccccctc ctcgtgcgcc
     6301 tggcgcagcg cgtcgagcgc ctccggcggc ggcggtgagg tgatggagcg ccaggccgga
     6361 acgacgacgg tccctgcccg ggcgatcgcc tccagcccgt acggcgcggt cagttcgagt
     6421 ccgccggtgg tccgcagcgg accgtcctcc ccggcgcaca cgagcagtcg gtagcgtgga
     6481 actcccgcgt cctgccggtc aatgccgaac acggagagtg gaatggaact ctcgaagatc
     6541 ggtccgccgc tgaacagcag caccgcgacg atctccctgc ggcgacgccc cgcgagtttc
     6601 cgacccgcgt ccacgacgac ggtggaatcc tggctcatgg cgctaagccc cccttgggtg
     6661 tcgcgactcc ttggtctggt cgcacctgca cgtttcccct cggcctcgca cgtggatccc
     6721 ccgccgtaaa tacatgatcg aatctactgc gtcccgtggt gtcggcgtga caagttcagc
     6781 acgcagcgct atgtcgactt ggcaacttgg cgaaaagcat tcgatcagta agcgttccat
     6841 tccgctaccg gggtgggaag cgcgccgccc ggccatggcc agtacccata gggtcgcgag
     6901 cctcccgggg ctctgtcgtc cctggtggta ggggggttgg ggggacattc cggcaagggg
     6961 gccaccctgt ccggaagttg gctgaaaaca tgcgggtgtg tgcgtgcgaa ccggtcagtc
     7021 ctgagggggc ggggtgccgg gcaccactcc cgggatccat tcgtaggcgg cgcagccgcg
     7081 gtgtgaaccg gccccgccgc gcgagtgccg gccgcggtgc gtgggcgcgg ccctgccggg
     7141 ctgccggccc cgcgcgaacg cccgggcggc ggtggcccgc tccatcttct ccgagtgccg
     7201 cagcagcacc cggcaggcgg ccgtgacggc ggcgagcccc agggtcgcgc ccaccgtccc
     7261 gccgaaggag gtcccgtaga cgacgaggac cacggggacg agcaggcagc tgaacgccgc
     7321 ccagcgcacc acgtcacccg cggggtcgtc atgggagcgc ctcgcgggcc gcacggacgg
     7381 gtgaagggcg gaggggggaa aggggtgcgc ggcgcggacg gagcgcgccg gctgggcggg
     7441 ctggacgggg tgaaccggat atccgggcac gtcgtactcc ctgcggctct tcctggacgg
     7501 tcggacgcct gtccaacgcc ccgcggcggg ggtcggtcac cgcgcacacg ggtggctcgt
     7561 cactggctgt aggggacagt ggtcattgcc aagccgccgc ctctccggca tgctccctgg
     7621 gacgctctcc aagggcggca tgccctgtgc aggacaggag tgtcgccgta ccctgggggt
     7681 aagggcttgg gaagatgctt cccggacaga gctccgtcac gctgtgtcgt tgaaaacctg
     7741 tgtcgtagaa aacctgcgcc gtccagaacc cgcgtcgccg aaaacgcccc tgtcgcttcc
     7801 ccaaggaccc cttcgccgag acatcatggc cggtcacgaa ttctccgaac ccgcggaccg
     7861 caagcgcaag ccagtcgccg accacacgtc cagcgacctg cgcgcggtgg aacaggcacg
     7921 ccatccctgc gacccggcct tccggcacgg cgtcgtggtg ggattcgacg gctcgacctc
     7981 cagtgagcgc gccctcgcgt acgcgatcgg gatggcccgg cgctccggat ccggtctgat
     8041 catcgtccat gtggccaacc ggctgcccac caccgtgtgg gccggctgtg agccgcccgt
     8101 cttcgtggac gtcccggacc accgcaccga ggtgctgggg ctggagctgg cctgcgccga
     8161 ctacctgtcg gaagtgccgt ggatcctggt cgagcgcggt ggggacatct gccacgagct
     8221 ggaggaggtc ggccgggagt attcggccga cgccatcgtc gtcggatcca cccacgggat
     8281 cgtcggccgg atcttcggct cggtggcggg gaggctggcc aagcgcgcgc agcgaccggt
     8341 tgttgtcatt ccgtgaccct gtgtatgccg atcgtgcggt tgtgaacccc cttgtaaagg
     8401 gtagataaat gctgctggga cgcagcaaac aactgcagat cgaagggagc ccgccgtgga
     8461 caatggtgtc tctgcgggaa gcacggcctc gacttcgacc ctcgggaaca tcgccctggg
     8521 tctcaccctt ctcgcgttcg gtatcggcca caccggtgtc atcaacggcg tgagcgcggc
     8581 cgactccgtg tcgctcgcga cctacctcgg cggtctcgcc ctcttcgtcc tcggagtcct
     8641 cgaattccgc gcgggcaacg ggttcaacgg gacggctttc gcgggcctcg gtgccttctg
     8701 gttcacctgg gccaacggag ccgacggaaa ggtttcggca gatgccgccg gcctcttcct
     8761 cgtcctcttc gccctcctcg ggctgaccct cacgacgggg gcgccccgcg ggccgttcgg
     8821 ccagggcgtg tacgccctgt tcaccctctc cctgctgctc ctcgcgatag gcgccttcgc
     8881 ggacagcggc gccctgggca aggccgcggg ctgggtggcc gtggtcggcg ggctgctcgc
     8941 ctggtacggg gcgacggccg tcgtggccgg ctggcccgcg gccttcggca ggggctcgcg
     9001 ccgggccgtg gtcaccgcga gctgacgcga acgggtacgg atgcgagtac ggccccccga
     9061 gaggctcggg gggccgtact catgtccgcg gtgtccggga aggactactc gacggtgacg
     9121 gacttcgcca ggttgcgcgg cttgtcgatg tcccggccca gggccagggc ggtgtggtac
     9181 gccaggagct ggagcgggat gcccatcagg atcgggtcca gctcgtcctc gttcttggga
     9241 acgaggatgg tgtggtcggc cttctcctgc tcacggtggg cgacggccag gatccggccg
     9301 ctgcgggcct tgatctcctc cagcgcggcg cggttcttct ccagcaggtc gtcgtccggg
     9361 acgatcgcga ccgtcggcat cgccggctcg atgagcgcga gcgggccgtg cttgagctcg
     9421 gaggccgggt aggcctcggc gtggatgtag gagatctcct tcagcttgag ggaggcctcc
     9481 agggccaccg ggtagccgcg gacccggccg atgaacatca tcgacttggc ctcggcgtac
     9541 tcggccgcca gcttcttgat gtcctcttcg gtctccagga tctcctggat ctgcgcgggc
     9601 agcttgcgca ggccctcgat gatccgcttg ccgtcggtga ccgacaggtc gcggatgcgg
     9661 ccgaggtgca cggcgagcag cgcgaaggcc acgaccgtgt tggtgaagca cttggtggag
     9721 acgacgcaga cctcggggcc ggcgtgcacg tagacgccgc cgtcggcctc gcgggcgatc
     9781 gcggaaccga ccacgttgac cacgccgagg acgcgggcgc ccttgcgctt gagctcctgc
     9841 accgccgcga gcacgtcgta cgtctcaccg gactgggaga ccgcgatgta gagggtgtcg
     9901 gggtccacga ccgggttgcg gtagcggaac tcggaggccg gctcggcgtc ggcggggatg
     9961 cgggccaggc tctcgatgag gccggcgccg atcatgccgg cgtggtacga ggtgccgcag
    10021 cccaggatct tgacccggcg gatgccgcgc gcctcgcgcg ggtccaggtt caggccgccc
    10081 aggtgcacgg tgttgaagcg gtcgtcgatc cggccgcgca ggacgcggtc gaccgcgtcg
    10141 gcctgctcgg agatctcctt gtgcatgtag gtgtcgtgac cgcccatgtc gtaggaggcg
    10201 gcctcccact ccacggtctc cggggtggcg gtggtggtgg caccgctggt ggtgtaggtg
    10261 cggaagtcgt cggccttcag ggtggccatc tcgccgtcgt tgagggtgac gatctggcgg
    10321 gtgtgggcga ccagcgcggc gacgtccgag gcgacgaaca tctccttctc gccgatgccg
    10381 aggacgaccg gggagccgtt gcgggcgacg acgatgcggt cggggaagtc ggcgtgcatc
    10441 acggcgatgc cgtaggtgcc ctcgatcacc ttgaccgcct cgcggacctt ctcctccagg
    10501 gtgtcggcct gggagcgcgc gatcaggtgg gtgatgacct cggtgtcggt ctccgagatg
    10561 aagacgatgc cgtcggccac cagcttggcg cgcagctcgt cggcgttgtc gacgatgccg
    10621 ttgtggacga cggcgacgtt gttgtcggcg tccaggtgcg ggtgggagtt gatgtcgctc
    10681 ggggcgccgt gggtggccca gcgggtgtgg gcgatgccgg tggtgccggc gaagcgcttg
    10741 gggacccggg actccagctc acggacgcgg cccttggcct tgacgacctt cagggccgga
    10801 gacttcggcg tgttgacgac gatgcccgcc gagtcgtagc cgcggtactc aaggcgctgg
    10861 agaccctcca gcagcagcgg tgccacgtca cgcttgccga tgtaacccac gattccgcac
    10921 atacggtgtt acccctcctg tttttcgttc gctcgtgccg tcttcgcctt cgccgccctg
    10981 tcgcggctcc ggcccttgcc ctgtccgtcc tccggccgcg ctcagccgta gacgacgcgg
    11041 cgcagctgcc ggagcgagag ctccggtggc gccacggcgc ggtgcggcag ttccgccgcg
    11101 atccgctcga agatctccgc gttgaccgcg ccaccggact ggagctcacg gtggcggcgg
    11161 cggacgaatt cctccgtcgt ctcgtcgaag tacgcgagca cgtccagcac cacccgggcg
    11221 gcctcaccgc gctggagcgc ggtgctgcgg accaggtggt cgacgagatc gtcgtgcgac
    11281 gggcggcggt cgagcatccg tagatactga ccgtcagcgg ggcggaatgc aaaaattctg
    11341 cccgattccg ggcaggatct tgctggtctg taccaacaga atgggatatt ccggttgagt
    11401 ggggtcagaa gcggcgcagg atcagcgcct tcgtctccgc gaactcctcg tccgtgagga
    11461 tgcccttcgc gcgcagatcg cccagctcct ggagccggcg cagcagggcg tcgtggtcct
    11521 cggcggcagc ctcgccggcg agggccccgg cggcgggcgc ggcccgttcc gggagggccg
    11581 cgggcgcggc cgggtggggc agccgaaccg ccacggcggc cgccacgagc gcggtgacca
    11641 gctccttctt gccgaagccg aagagctcca ccgcgtgcgg gtcgtacttg ggggcggccg
    11701 ccgccggggc gcccgccagg gagaaccgga gccagccgtt cgtcagcccc ttcgccgggg
    11761 accagtccac cgcccggacg tccgccaccc ggaaccggct gggaccggcg gagtgcttgg
    11821 cgtcctcggc cgtccagttc cagtccaggg acacccggtc cccgtcgaag gccaccgccg
    11881 cgtcgccccc gcccgccgtg accggcaccg ccggcccggg cagcaggtag gcgtccaccg
    11941 ggcccggatc cacctgctcc agcagcaggg cgttgcgcac ctcgtcgacg aagtactccg
    12001 ccactccggt gcggtcctgc tcgaccgtga gccggtaggg gtcggagctc tccggcagcc
    12061 gcccgcccgt cacctggagc agcgggtcgg ccccgtcccg cagccgcagg cgcaaccggc
    12121 ccgacctgcg gcccggttcg taggagacgc ccgcgatcgc gcgcaggggt acggccagct
    12181 cgccgagcgt ctggcgcagc ggcccgacct ccttgtcgcg gccggggacg atacgcacca
    12241 cgtcaccgtc gaaggtccag gtgccgtcct tctggatgat ttccgccatc ctgggattct
    12301 cgcacccgcg cggggccggg agttggccta tacctgggca catgagagtc ctgcgacgcg
    12361 cgctcggtac cctcctcgcc ctcggtgcgg ccgtctcctg caccgcggcc cacggcgacg
    12421 acgccagacc cgggggcgac cgccccgccg ccctcacccc ctacgaacgg ctcctgccgg
    12481 cgcccgcctc cgcccgcccc ggcggccccg ggtacccctt cggcgcgggc accgtcatcc
    12541 gtaccggccg cgccggcggc gccgccggcg cggaggtccg ccgggtcggc gaactcctcg
    12601 ccgggcagct gcgcgggccc agcgggctgc cgctgcccgt ggtcgacggg gaggccggcg
    12661 acggcgtccg gctgcgcctg gacgggcggg ccgccgggct ggggcccgag gggtaccggc
    12721 tggaggcctc ggcctcgggg gtcaccctga ccgcccgcac cccggcgggg ctcttccacg
    12781 cggggcagac gctgcgccag ctgctgcccg tgagcggccc ggggacggtg cccggcggga
    12841 ccgtcaccga cgcgccgagg ttcgcgtacc gcggcgcgat gctcgacgtc gcgcgccact
    12901 tcttcgggat cgaccaggtc aagcggtacg tcgaccagct cgcccagtac aaggtcaaca
    12961 cgctgcacct gcacctgacc gacgaccagg gctggcggat cgccgtcgac ggctggccgc
    13021 ggctcgccga gtacgggggc gcgggcgagg tcggcggcgg ccccggcggg tactggacga
    13081 aggacgagta ccgggagctg gtggcctacg cccgcgagcg gtacgtggag gtggtccccg
    13141 agatcgacat gccggggcac gtcaacgcgg cgcaggcctc gtacgccgag ctgaactgcg
    13201 acggcaaggc gcgggagcgg tacacgggga ccaaggtggg cttcagctcg ctgtgcgtcg
    13261 gcaaggagcg gacgtacgag ttcatcgacg acgtgctcgg cgagctggcg gagctgaccc
    13321 cgggccgcta cctccacatc ggcggcgacg aggcgcactc gacccccgcc gcggactacg
    13381 cggcgttcat ggaccgggcg cagcaggtgg tggcgcggca cggcaagacg gtgctggcct
    13441 ggcaccagct ggcgacggcc cgtccggcgg cgggcgcggt cctccagtac tggggccacg
    13501 acaagacccc ggcggccgag aaggcggcgg tggccgcggc ggcccgggcg ggccacccgg
    13561 tgatcctctc gccggcggac cggctgtacc tggacatgaa gtacgacacg gcgacgaagc
    13621 cgggcctggc ctgggccggg tacgtcccgg tgcggcgggc ctacgactgg aacccggggg
    13681 cctacctgga gggggtggcg gagtccgccg tcctcggggt ggaggcgccg ctgtggacgg
    13741 agaccatctc ggcccgggcc gatctggagt acatggcctt cccgcgcgtg ctgggcctcg
    13801 cggaactggg ctggtccccg gccggcgccc tggactggac ggcgtaccgc cagcgtctgg
    13861 cggcgcaggc cccgcgcctg acggcgcagg gcatcgcctt ccaccgcgcc ccggacgtcc
    13921 cctgggggcg gtagccgcac gcgcaaaggc gggccccgcc ggacgaggga ccgtatcgtc
    13981 cggcggggcc cgctcgatgc ctaccggcgc gcgaagggcg cgacggggtt cttgagggtg
    14041 ccgatcagct ggagggccgc cgccgggtcg gcgaggtcga ccatctgctt gttgttgcgc
    14101 agctggaggc ggttcaggca ggacagctgg aactcctccg cgaagtagtc gtaccgctcg
    14161 aagcgctccg cgagctgcgg catcgactcc tggtaggcgt ggccgcagtc ggcgaccgcc
    14221 ttccagaagg tgtcctcctc gcagatgccc tccgagacca ggatcgagcc caggaagcgg
    14281 aagaagcagt cgaacacgtc cgtaaagatg gacagcagct tcatgtcctc cgggatgtcc
    14341 gcccggaccc gctcgaccgc gggcggcagg accgcgtccg ggtccatgac cacgatctcc
    14401 tcggcgatgt ccttgaagat cgcccgcttc accacgccgc cctcgatgac gaggatggtg
    14461 ttctcgccgt gcggcatgta cgcgaggtcg tactggtaga agcagtgcag cagcgggacc
    14521 aggtacgcct tgaggtagga gcgcagccac tcctcgggcg tcaggcccga ctccgcgatc
    14581 agggcgccga cgaaggactt gccctcggag tccacgtgca ggagcgaggc catcgtcgcg
    14641 agccgctcgc cgccccggag ggaggcgacc ggggactcgc gccacagcgc cgccagcatc
    14701 ttgcggtacg gcgagtagcg gtcggtggcg cgctcgtact ggcggtggtg gtagccgatc
    14761 gccgcgcgct cgcggatgat cgagaagtcc accgaccgca agacctcgtc gccctcgatg
    14821 agctggtgca gccagtcgtt gatggccggc gtggcctcca tgtacgcggc cgacaggccc
    14881 cgcatgaagc ccatgttgag caccgagatc gccgtcttga cgtagtgctt ctcgggggcg
    14941 ctggtgttga agaacgtacg gatcgactgc tgggccaggt acgcgtccga gccctcgccg
    15001 agcagcacca gacggcggtt cgcgatctcg gccgcgaagg tgaccgtggt cttgttccac
    15061 cactgccagg ggtggaccgg cagcaggtgg tagtccgcca ggtccaggcc gagctccgcc
    15121 atccgcgccg agaaggccgc gatggtcccc tcgcccagct cctcgcggac gaacgagtcg
    15181 tagtccatgc ccgcgcccgc cgtgaaggtg gagacgtcct tgcgggccgc cacccacacc
    15241 aggtgcacgg ggttcgcggt ctccggggcg tacgagaggt actcgtgcac gccgaagccc
    15301 aggcggccgt tgttggccac gaagcagggg tggccctcgg tcatgccggt ctcgatgtcc
    15361 tggaaggagg acttggcgag gacggcggag gagacctgcg gcttcgtgta cttgtagccc
    15421 gagcccgcca gggtggagga gatctcctcc aggtagaccg gcagcacctc ggggctcagg
    15481 cccagggcct cgcgcagctc gatgtggaag tcgagggcgt ccagcggcag ctcggcgccg
    15541 tcgcggtggc gggtgatgga ggcctcgtcc acggcccagt ggtccagggc gtgcagctgc
    15601 gcctcgaagc ggtactccac ggtgccgtcg tcgctccgca cggagtacga ggagccgccg
    15661 agcggcttcg gggtcaggag tcgctcgtgc gagaactcgg ccaggccctt gcggaccagg
    15721 gcgcggttcg cgcggtccca cagctcgggg gagaggtggg agatggcgtc ggtgaggctc
    15781 atatggactc tcccgtcagg ccggtggccg cttcgaactg ggcgcgggtg cagaagctca
    15841 gcagggcttc cttctccggc ttcgtcacgg ggcgctcggc gacgaagccg acggcctcgt
    15901 tgagggcgtg cacggccgtg ttgttcacgt ccggctcgac gacgacgcgc tcggccgccg
    15961 ggtccgcgaa gacggccgcc atcacggtgg tgatgaccgc gcgggtgaag ccgtgcagcg
    16021 gcgtgtcgct cggggcgacg aggaagtgca tgccgacgtc gccgggctgg gcgtcgtaca
    16081 ggccgacgag ctccagctcg ctcgggtcgt acgtctccat caggaacgcc gggcggccct
    16141 cgtgcaggcc gatgaaggcc tggtggtgct cgtgcgccgc gatccgcatg tactcgcgct
    16201 cgacgtccgg cagcgtggcg tcctgcatca tccagaacga ggccttcggg tgggtgaccc
    16261 agccgtgcag cagctccgcg tcggcgaacg ggtccagcgg cctcacggag aaggtgccca
    16321 gttccgcgtc ggtgcgggcg tacaggattt cggtggtgct catgcgtgca tgccttccgg
    16381 ggccgcgaac tgctggaacg cgatggactt ctcgaccttg tagtactcgc ggccgagcag
    16441 ctcgccgacg atgtacgcgt tgcggtacgc ggccatgccg aggtcgggcg aggtgatcga
    16501 gtggttgtgg gtcgtgccgt tctggaggta gaccccctgg ccggtggtgt ccacgctgta
    16561 gttgcgggcg gcgtcgaggc ggccgtgccc gtcgaagttg aggcgcggac ggaccgggtt
    16621 caggaactcg ggcacgacgt acttgtagcc ggtggccagg accaggccct cggtggcgag
    16681 ggagaagtcc cgctcctgct cctcctggcg cagccccagg gcgtaggtgc ccgtggtggt
    16741 gtcgtacgcc gtggtgttca gggaggtgtt ggtcagcagg gtggtcggga cggggcccgg
    16801 catgctgacc ttcttctggt agagcaggtc gaagatctcg ttgatcagat cgccgtcgat
    16861 gcccttgaag aggttcttct gctgggtctc cagccggtag cgggtctcct cggggagggc
    16921 gtggaagtag tccacgtact ccggcgaggt catctccagc gtcagcttcg tgtattcgag
    16981 cgggaagaag cgcggcgagc gggtgaccca gttgagctgg tagccgtgga cgtcgatctc
    17041 ggcgagcagg tcgtagtaga tctcggccgc gctctggccg gagccgatca gggtgatcga
    17101 cttcttcttc tgcagctcct ccttgttctg catgtaggag gagttgtgca ggaagtcccc
    17161 gccgaggttc gcgcaggcct gcgggacgta gggcgaggtg ccggtgccca ggaccaggcg
    17221 gcgggccagg tgggtctcgc ccttgtccgt gcggacctcg tagagcccgg cggcctcgtc
    17281 gtaggtgacc tcgctgacgg aggtggacca caggacgttg tcgaggcggt cggcggccca
    17341 gcggcagtag tcgttgtact cggcccgcag cgggtagaag ttctcccgga tgtagaagga
    17401 gtacagccgg tcctggtcct tcaggtagtt caggaaggag aagggcgagg tcgggtcggc
    17461 cagcgtgacc aggtccgaca tgaacggggt ctgcaggtgc gcgccgtcca ggaacatgcc
    17521 ggcgtgccac tcgaagtgcg gcttcgactc gatgaagaga ccgtcgagtt cgtcgatcgg
    17581 gtcggtcagg caggcgagtc ccaggttgaa gggaccgaga ccgattccga tgaagtcgtg
    17641 gggcttaacg gtggacggca agggattctc ccaggaactg cgcggcgtgt gcggcgagaa
    17701 ggtcgaggac ggcggagatg tcggccgtcg tggtctgagg gttgaggagg gtgaacttca
    17761 ggtactgctt cccgtccacc ttggtgccgg ccaccacggc ctcaccggag gcgaacaggg
    17821 ccttgcgggc gtgcagctgg gcctcgtcca ggagctcggc gggcaggtcc gcggagtccg
    17881 gaccgggcac gtagcggaag accagggtgg agatctgcgg cttgacgacg acttcgaagc
    17941 gggggtcggc gtcgatgatg tcccagccgg ccgcggccag gtcgatgacc tcgtcgaaga
    18001 gggagccgag gccgtcggcg cccatggtgc gcagggtcat ccagagcttg agcgcgtcga
    18061 agcggcgcgt ggtctggatg gacttgtcga cctggttcgg gatccgctcc tccgccatgc
    18121 ggcgggggtt gaggtagtcc gcgtggtacg tggcgtgctt gagggtgtcc cggtcgcgga
    18181 ccagtaccgc gctggagctg acgggctgga agaacgactt gtggtagtcg accgtgacgg
    18241 agtcggcgtt ctcgatgccg tcgaggaggt gccggcgcgt cggggagatc agcagtccgc
    18301 agccgtaggc ggcgtccacg tgcatccagg cggagtgctc ggaggtcagg cgggcgatct
    18361 cggggagcgg gtcgatggat ccgaagtcgg tggtgccggc ggtcgcgacg acggccatcg
    18421 ggaagaggcc gtcgcggcgg cagttctcca gctccagggc gaggatcgcg gtgtccatgc
    18481 ggcggttgcg gtcgaccggg acggagatga ccgcttcgta gccgaggccg agcatcgcgg
    18541 ccgacttctt gacgctgaag tggctggcct cggaggtgaa gatgcgcagc ttggggagga
    18601 cctcggactt cgggagttcc cggccctcgt tcagtgcctg cttcatgacg atccggcagg
    18661 cctcgtcgcg ggccagcagg agcgcgtgga agttggactg gctgccgccg gaggtgaaga
    18721 cgccgtccgc gccctcgccg aggccgatgc gctgggcggt ccagtcgatg aggcggcgct
    18781 cgatgagcgt gccgccgatg gactggtccc aggtgtccag cgaggagttg acggccgaga
    18841 ggaccgcctc gccgagtacg gccggtatca cgacggggca gttgaggtgg ccgaggtagc
    18901 gcgggtggtg gaagtacacc gcgtcgcgca ggtagacgtc ctccagctcg tcgaggacgg
    18961 cggccgggtc ttcgagcggc cggtccaggt cgatcccgtt gatgaccggg gcgagttcgt
    19021 ccacggatat gccggtgtgg ggccgttcgg tggtcgcgag tttggcggcg acacgcgcga
    19081 cgccctcggt cacggtgcgc cggtagatgt ccgcggtcgt ctcattcagc agatgcgagc
    19141 gcatcaactt tcctccgggc aggcaggggg agcggggggt ggggtgctgg attaggttag
    19201 cctaacctaa cagtcaaacc aaatagggat gggccccggt cggaaccggg gcccatccct
    19261 gaagtcgtcc gagggcggaa cgagttgccg cgaggcggcg atcggcgagg tgcggggtgt
    19321 gctcggctac agcgcggacg ccgggtcctc gctggccgac ttgccggcgt acgcctcggc
    19381 gaggagttcc tcctcgctcg cgccgagccg ccagtaaccg gtgaagcgca ccgcgcgccg
    19441 gtcgatggaa cgttcctgca cgatgtgccg gcggaccgcg cggatggtgc ccgcctcgcc
    19501 cgcgagccag acgtacgggg cctcggcctc gggcagttcg gccacgcgca tcgcgtcgag
    19561 cacccgctgg acgcgctcct cgcggcccgc tccgccctcg cggacgatcc aggtgatctc
    19621 cgcgtcggcg agggtgggca gggcgagccg gtcgtcctcg tgcgggacct cgaaccaggc
    19681 ccgcacgcgg gtgccggagg cgagccggtc caggatcgcg gcggccgcgg ggagcgcggt
    19741 ctcgtccgcg tacatcagca gcgcgtcggt ggcggccggc ggctggaacc gtacggactt
    19801 gttctccgcg acggccgggc cgatcgccag gatccggcgg ccggcaacgg cccccgaggc
    19861 ccagcgggac gccggcgagg cgtccccgtg gaggacgaag tcgatgtcca cctcgtccgc
    19921 gccctcgggc gtacggcgct gctcgcgcac cgtgtacgag cgcatcaccg ggcggtcggc
    19981 gtcgggcatc gcgcgccacg cgccgaacca ggtgtcctcg tcggtggacg ggagcaccgt
    20041 gtgctcctcg tgggcgggcg gcaggaagag cgagaggctc tggtcacagc cgcccgagcg
    20101 gaagtccgcg agggacccac cgccgaacgt gacccgcagg aacgagtggc cgagccggcg
    20161 cgtgcggagc acttcgagtt cgaagaaccg gaagtgggcg atggccgggg cggtgtcgga
    20221 tgcggtgacg gtcatgcggt gggtccccct gggaattcgg gtggcgccgg gtcgggcgcc
    20281 cgggttcagc tgaccttctt ggcgttctgg atggccttgg cgaggtcttc caggatctgc
    20341 gcgcacttct cgtacgagta gatcggctcg gtcacgcgcg gggcgacctg gccggccttg
    20401 acggcgggca tctcggccca ggtcggcttg gccttcagct cctgcgactg gagggtgccg
    20461 gtgcggttgt cgagcaggac caggtcggcc ttgtacttgc cggcgttctc ccagctgagg
    20521 ctctcgaaga agccgcccgc gtccagcttg tccttgtccg gggtgatgaa ctcgacgccg
    20581 agggtctcga agtacttgag gtcggcggag gtcttcgggg tggagacgta gaacaggtcg
    20641 gcggagccgg agccgacgag caccttgatg cccgggttgg ccttggtggc ctcgcgcacc
    20701 ttggcggcgg cggcctcgaa gcgggccttc gcgtcggcgg tcttcttgct gttcaggtcg
    20761 gcgcccaggg acttggccag gtcggccgtg cgctccaggg acttgtcgag ggaggcgtcg
    20821 ccgcccacgc cgatggcggc ggccggggcc agcttcagga tcttgtcctt ggaggcctcc
    20881 gggacgtacc agtaggtgcc gtcccaggtg ttggtgacga gcagctccgg ctggagggcc
    20941 gcgtacttct cgacgttgaa ctcgtcgtag acgttgccga ggatctcgac cttggagatg
    21001 tccatcgagc cggcctggac gtcgggcttg ccgtcggcgg tcttggtcgg gccgaacacg
    21061 cccttgacct ggacgccgta gtcgtagagc gcggcggcgg tgccggtgta ggccacgatg
    21121 ttcttcgggg cggccttcag gctgatgtcc ttgccgaggt cgtccttgaa ggtccaggga
    21181 cccgaggcgg cggcgccctt gtccttgtcc ttgcccgtct cgcccttcgc ggagtcggtg
    21241 ccgccgcatg cggagagcgc cgcgacgagg ccgagggcgc cgccggccgc gatgagcccg
    21301 cggcgggaga ggtaggaggt acgggacttg ggcatgtcga tgtccgcttt cgtgcgtgtc
    21361 aggcggccac tgggccgttc ggagggaagg ttagcctaac cttggccgaa aacggtaagg
    21421 gggccctaag ttttttcagg gccccctcgg tgtacgatcc gccgccgtcc tccgcgctag
    21481 gaggagaagc ccagctcgcg ggcgatgagc atgcgctgca cctcgctggt gccctcaccg
    21541 atttcgagga tcttcgagtc ccgccacatg cgcgccaccg ggtactcgtt catgaagccg
    21601 tagccgccgt ggatctgcgt ggcgtcccgg gcgttgtcca ccgcgaccgt ggaggagtac
    21661 agcttggcga tcgccgcctc cttcttgaac ggttccccgg ccaccaggcg ggaggccgcg
    21721 tcgcgccagc cgatccgggc catgtgggcg cgcatctcca tgtcggccag cttgaactgg
    21781 atggcctggt tgtcgccgat cggacggccg aaggccttgc gctccttcgc gtacttcacc
    21841 gactcgtcca cgcagccctg ggcgaggccc gtcgcgagcg ccgagatggc gatccggccc
    21901 tcgtcgagga tgcggaggaa ctgggcgtag ccgcggccct ccgcaccgac caggttggcg
    21961 agggggaccc gtacgtcctg gaaggacagc tcgcgggtgt ccgaggagtt ccagccgacc
    22021 ttggagtacg gggcggccac cgtgaagccg ggggtgccgg acgggacgat gatcgaggag
    22081 atctccgggc ggccgtccgc cttgcggccg gtcacggcgg tgacggtgac cagaccggtg
    22141 atgtccgtac cggagttggt gatgaagcac ttcgagccgt tgatgaccca ctcgtcgccg
    22201 tccttgacgg cggtggtgcg ggtgccgccg gcgtcggagc cgccgtccgg ctcggtcagg
    22261 ccgaaggcgc cgaggatctc gccggagcac atcctcggca gccactcccg cttctgctcc
    22321 tcggtgccga acaggtggag gggcatggcg ccgagggaga cgcccgcctc cagggtgatc
    22381 gcgaccgagg agtcgacgcg ggccagctcc tccagggcga tgccgagggc gaggtagtcg
    22441 ccgcccatgc cgccgtactc ctccgggaag ggcaggccaa acaggcccat gcggcccatc
    22501 tcgcggacga tctcgtacgg gaactcgtgc cgctcgtaca ggtcgccgat cttgggggcg
    22561 acgacgtcgt gcgcgaactc ctcgacggtg cggcggagtt cctcgtgctc aggggtgagc
    22621 cggtggtcga gggacatgtt ttcgttactc cttgtgggag agggcgcgga cggtacggga
    22681 ggggctgggg cggcccagct gttcggccat ccacacgctc gtggcggtga gggcggccag
    22741 atcgacgccg gtctcgatgc cgaggccgtc gagcatccac accaggtcct cggtggcgag
    22801 gttgccggtg gcgctcttgg cgtacgggca gccgccgagg ccgcccgccg aggcgtcgac
    22861 cgtggtcacg ccgtgctgga gcgcggccag ggtgttggac agggcctggc cgtaggtgtc
    22921 gtggaagtgc acgccgatca ggtcggcgcc gacgccctcc tcgcccagct cgccgaggag
    22981 cgcccggacg tgccccggcg tggcgacgcc gatggtgtcg ccgaggctga gctcgtcgca
    23041 gccgaggtcg agcagggcct tggcgacgcg gaccacctgg cggaccggga ccggcccctc
    23101 ccaggggtcg ccgaagcaca tggagaggta gccgcggacg tgcgccccgc cctccttggc
    23161 gcgggccacg accggctcga acatcgcgag ggactcggcg acggtccggt tgaggttgcg
    23221 ggaggcgaag gtctcggtgg ccgaaccgaa gacggcgatc cgggtcgccc cgagggcgag
    23281 cgcccggtcc agcccgcgct cgttggggac gagcaccggc aggtgcaccc cgggcaggtc
    23341 cgacagctgc gggaacagct cctcggcgtc cgccagctgg gggacccact tggggtgcac
    23401 gaagctggtc gcctcgatgg tggtcagccc ggcggcggcc agccggtgca cgaactcggc
    23461 cttcacctga gtgggcacgg ccgacttctc gttctgcagc ccgtcgcggg caccgacctc
    23521 gtggatccgc acgcgcgccg ggagtgcggg ggcggggacg gtcatgggaa gcccgttcac
    23581 ttgccctcct cctcttctcc tcgcggctcg tccggcgtga cgaccgcgag gacctggtcc
    23641 atcgcgacgg tggtgccggg ggagacgtcg agctcggcga cggtgccgga gtgcggggcg
    23701 gagatgacgt gctccatctt catcgcctcg acgacgagca ggctctgacc ggccgtcacc
    23761 ttgtcgccga cggccacctt gacgacggtg acggtgccgg gcatcggggc ggccagcgtc
    23821 tccgccccgg cgtggccgcg accgctgagg gccgcggtga cggggtcgtg ggcctggacg
    23881 tgccagctgt cgccgtcccg gccgagccag gtcccttcgg gggagcgggc gtggctgaag
    23941 gtgtgcgtga cgccgtcgag ttccaccgtg acgcggtcct cgccccggct gacgatccgg
    24001 ccccgggccg gcgcgccgga gtcctcggcg agtaggagct ccgtctcggc gcccgagggg
    24061 cgggagcgga ccgacaccgg ctcctggccc gggaggcgga agtggtggac cgtccaggcg
    24121 ggggtaccgc ccaggcgcca gccgtcgccg gccccgaagg ggtcgaccca gttcccggaa
    24181 ggggagggga gggcggggcg gtgggcggcc agcagggccg ccgccgcgaa gacctccggc
    24241 gggacgccct ccgggagcag cgtcgacagg tcgcgctcca ccagaccggt gtccaggttg
    24301 cccgacacca cgtccgggtg cgccaggagc ctgcgcagga aaccggtgtt ggtctggacg
    24361 cccaggatca ccgtgtccgc cagggccccc cgcaggatgc gcagggcggt ggcccggtcg
    24421 gggccgtacg cgatcacctt cgacagcatc gggtcgtacg tcgagccggt gtccaccccg
    24481 gccaccaggc cggagtccgt ccgcacggac ccgcccgacg gctcggacag cgccagcacc
    24541 gtccccccgg agggcaggaa gccccgcgcc gggtcctccg cgcagacgcg ggcctcgacg
    24601 gcgtgcccgg tgagggtgac gtcggcctgg ccgaagccca gctccgcgcc ggaggccacc
    24661 cgcagctgct gctccaccag gtccagcccg gtgatcagct ccgtcaccgg gtgctccacc
    24721 tggagccggg tgttcatctc catgaagtag taggaggacg ggtccccgcc cgggacgatg
    24781 aactccaccg tccccgcgcc cacgtacccg cacgagcgcg ccgcctccac cgccgccgcg
    24841 cccatcgagg cccgcagctc cggcgtcagc aggaccgacg gggcctcctc gatcaccttc
    24901 tggtggcggc gctggagcga gcactcgcgc tcacccaggt gcaccacgtt cccgtacgag
    24961 tccgccagca cctggatctc gatgtgccgg ggccggtcca cccagcgctc cacgagcagc
    25021 gtgtcgtcgc cgaacgagga cctcgcctcg cgccgcgccg ccgcgatctc ctccgcgagc
    25081 agcccggcgt cccgcaccag ccgcatgccc ttgccgccgc cgcccgccga gggcttcagc
    25141 agcaccggca tgccgatctc ctcggccgcc gcgacgagtt cggcatccga cagaccgctg
    25201 ccggacgagc cggggaccac gggcacgccc gccgccttca ccgtctcctt ggcccggatc
    25261 ttgtcgccca tcagggagat cgccttggcg ggcggcccga tgaaggccag ccccgcctcc
    25321 gcgcacgcct gcgcgaaacc cgcgttctcc gcgaggaagc cgtaccccgg gtggatcgcc
    25381 tcggccccgc tgcggcgggc ggcgtcgagc agccgctcca ccgacaggta gctctcggcg
    25441 gccgcagccg ggccgatccg gacggccgtg tcggcctccc gtacgtgccg ggcgtcggcg
    25501 tccgcgtcgc tgaagacggc aaccgagcgc accccgagct cccgcagcgt gcggatgacc
    25561 cggaccgcga tctcgccccg gttggcgacc agaacagtgc tgaacatcag tgaggtcctc
    25621 acgtcacata cggaagatgc cgaagccgcg atcgcccagc ggggcgttcg cgcacgcggt
    25681 cagggccagt cccagcacct gccgggtctc catcgggtcg atgaccccgt cgtcccacag
    25741 ccgcgcggtg gcgtagtagg cgttgccctg ctcctcgtac tgcgcgcgga ccggggcctt
    25801 gaaggcctcc tcgtcgtcgg ccggccactc ctggcccgcg ccctcgatct ggtcgcgctt
    25861 gacggtggcg agcaccgagg ccgcctgctc gccgcccatg acggagatct tcgcgttggg
    25921 ccacatccac aggaaccgcg gcgagtacgc ccgcccgcac atcgagtagt tgcccgcgcc
    25981 gtacgagccg ccgaccacca ccgtcagctt cgggacccgg gtgcaggcca cggccgtgac
    26041 catcttggcg ccgtgcttgg cgatgccgcc ggcctcgtag tcgcgtccga ccatgaagcc
    26101 ggagatgttc tggaggaaga ggagcgggat cccgcgctgg tcgcacagct cgatgaagtg
    26161 cgcgcccttc tgggccgact cggagaagag gatgccgttg ttggcgacga tgccgaccgg
    26221 atggccgtgg atccgggcga agccggtgac cagcgtcgtg ccgaactcgg ccttgaactc
    26281 ctggaagcgg gaaccgtcca cgaggcgggc gatgatctcg cgggcgtcgt acggggtgcg
    26341 ggagtccacc gggaccgcgc cgtacagccc ggccgggtcc accttcggct cctcgggggc
    26401 ctccaccgac cagggcagct ccccgcgccc gggcagggtg gccacgatgt tccgtacgat
    26461 ccgcagcgcg tgcgcgtcgt cctccgcgag gtggtcggtg acgccggagg tccgggagtg
    26521 gacctcgccg ccgcccagct cctcggccgt gacgacctcg ccggtggccg ccttcaccag
    26581 cggcgggccg ccgaggaaga tcgtgccctg gccgcgcacg atgacggcct cgtcgctcat
    26641 cgccgggacg tacgcgccgc ccgccgtgca ggagccgagg acggccgcga tctgcgggat
    26701 gccggcgccg gacatgcgcg cctggttgta gaagatgcgg ccgaagtggt cccggtcggg
    26761 gaagacctcg tcctgcatgg ggaggaaggc gccgcccgag tcgaccaggt agaggcaggg
    26821 gagacggttc tccagggcca cctcctgggc gcgcaggtgc ttcttgacgg tcatcgggta
    26881 gtacgtgccg cccttgacgg tggcgtcgtt ggcgacgatc acgcactcgc ggccgctgac
    26941 ccggccgatg cccgcgatga ccccggcggc cggggccgcg cccccgtaca tcccctcggc
    27001 ggccagcggg gccagctcca ggaacgggga tccggggtcg aggagggcgt ccacgcggtc
    27061 gcggggaagc agcttcccgc gggcggtgtg gcgggcgcgg gccttgtcgc cgccgccgag
    27121 ccgggccgcg ccgagccggg cgcgcaggcc ctcggtcagc tcgcggtggg cggcctcgtt
    27181 ggtccgccag gcctcggacg ccgggtccgc ggcgctcgtc agcactggtg cctgctgcat
    27241 cggtcgagct cccttgctcg gtgcacgctg ttaatgagcg ttaacgcatg taccgcctag
    27301 gttaacgagc gctaacggcc ctgtctagaa tggattccca tgagcaccag tgccgccgcc
    27361 ccgacccgtc gcgagcagat cctcagcgag gccgcccgcc tcttcgccga gcgcggattc
    27421 cacggcgtgg gcgtggacga gataggggcc gcggtgggca tcagcggccc cggcctgtac
    27481 cggcacttcg cgggcaagga cgccatgctc gccgagctgc tggtcgggat cagcgagcgg
    27541 ctgctgaccg gcgggcgccg ccgggcggag gaagcggccg gggacccctc cctggtgctg
    27601 gcctcgctca tcgacgggca catcgacttc gcgctcgacg accgggcgct gatcaccgtc
    27661 cacgaccggg agctcgaccg gctgcgcgat gccgaccgca agctcgtgcg ccagttgcag
    27721 cgccagtacg tggagctgtg ggtggccgtc gtgcgcgagc tgcacccccg ggtgggggag
    27781 gcggaggtcc gggtctccgt acacgcggtg ttcggcctgc tcaactccac cccgcacctg
    27841 gcggcgctgg gccgggaggc gaccgaatcg ctgctgcgca ggctcgcgca cggatcgttc
    27901 ggggcgctct ccgggtgatc cggcgcgtcc gctgggcggg acggacggga cgcgtccgcc
    27961 cgggcggcgg cagaatgggc cgtatgccga tgccgataga gacgtccgta cccacccgag
    28021 ccgaactcat cgaccacctg gtccgcaccc ggatcgccgg ggacgtcgcc acgccacgcg
    28081 agaacaacct ctcccactac cgcaagctcg ccaacggcga tcggcactac tggctcggcc
    28141 tggaactggg cgaccgctgg gccgacgagc aggacgtcct cgcggtgatg gcggagcgct
    28201 gcggcgtcgt ggacgacccg cagcaccgcc agggccagga caccatcgac ccggaactga
    28261 ccgtcgcggg cctggagcgg ctggcggcca ggctgcggaa ggccgcgctg gaccggcaga
    28321 gcgtgctgct cgccaccggg cacccgggcg gcctgctgga cgtccaccgg gcgacggcgg
    28381 tggcgctgcg cgccgccggc tgcgagatcg tggtcatccc ggccggtctg acggccgacg
    28441 agggctcggt ctggcagttc gcggacatcg cggtcctgga gcggggcgcg accctgtggc
    28501 acacccactc gcccgcgccg atggcggcga tcctggacgg cctggccgcc gccgggcgcc
    28561 cgcagccgga cctggtcgtc gccgaccacg gctgggcggg ctgcgccgcg cagcgcggcc
    28621 tggacgcggt gggctacgcg gactgcaacg acccggccct gttcctcggc gaggccgagg
    28681 gcaccctcca ggtggcggta ccgctggacg accacgtccg tgacccgagg tactacgacc
    28741 cgatggtggc gtacctgctc gcgacggccg gtctgctgta accggcggac ccggtgcggc
    28801 ccggccgtcg ggggtggcgc ggggtcagcg cagccagccg ccggtgaggt cctggacggc
    28861 ggagccgtcc aggtcggcga gcttggtggc gacgaactcc cgcgcccagt cggaggtctg
    28921 gatccggaac ggcatcgtct cggcggtcag cgccgcgatg atcggcgccg ccgcctcctg
    28981 cgaggtctgg gcgttgccga aggactgcat ggtgcgctcg atgtaggcct tcagcgcggg
    29041 ggcgtacgga ccggcctcgg cgagcagggc cgggacgtcg agccgtacgt tggtgacgaa
    29101 ctcgctggcg acggcgcccg gttcgacgac ggccacctgg acgccggtgg tggcggcgac
    29161 cggcgccagg gactccatga agccctcgac ggcgaacttg gccgcgcagt acgactcgtt
    29221 gaacggctgg ccgatcatcc cgccgacgct cgtcacggtg atgacccggc cgccggaggc
    29281 gcgcaggtgg gggagcgcgg ccttggtgag ttcgacgacg ccgaagtagt tgacctccat
    29341 ggtggaccgg acgccctcca tgccgtgctg ctcgatggtg ccgacgaagc cggcgcccgc
    29401 gttgttcacg acggcgtcga gaccgccgcg ctcggcgacg acctccgcca cgcaggaggc
    29461 gacggatccg gcgtcggtca cgtccagccg cttgacctgg accaggtcgg cgacgccggc
    29521 ttcggcggcg gcctcgcgca gggcgtcggc cttggcggtg tcgcgcatgg tggccacggt
    29581 gtgccagccg gcctgggcgg cggccacggc ggcggccagg ccgatgccgg aggacgtgcc
    29641 ggtgatgagg acggtcttgg tgctcatgga ggtctccctg gatttgtgcg tgcacacaca
    29701 cattatcttt gtgtgcacgt gcacgcaacc cgggtactct tttcccatgg cgcacagcga
    29761 actcaacctg gacggcctca cc
//
