LOCUS       NZ_BMVE01000003        27708 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces goshikiensis strain JCM 4640 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVE01000003
VERSION     NZ_BMVE01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 698120)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650555.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:30:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,491
            CDSs (total)                      :: 7,410
            Genes (coding)                    :: 7,286
            CDSs (with protein)               :: 7,286
            Genes (RNA)                       :: 81
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 44 of 125
            Pseudo Genes (incomplete)         :: 101 of 125
            Pseudo Genes (internal stop)      :: 9 of 125
            Pseudo Genes (multiple problems)  :: 27 of 125
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 187421
            Orig. end                         :: 215129
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVE01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27708
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="melanin"
                     /region_number="3"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..27708
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27708
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:22708]"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..22708
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
     gene            complement(174..1352)
                     /locus_tag="IE248_RS10960"
                     /old_locus_tag="GCM10010336_22280"
     CDS             complement(174..1352)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE248_RS10960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010336_22280"
                     /product="hypothetical protein"
                     /protein_id="WP_190030609.1"
                     /transl_table=11
                     /translation="MRNSMSAAGAATAAAIALAGLITAAGPAAAAAPGPAAAKACAPAV
                     VKLADIAAGPAGAGNGGTVKAFGANGLIAGQSRGLPAYWTADGTAHAVPVPEGFQSGEV
                     KAVNAKGLMVGALRRPGDYDHSFAFTYQQGAAAVALVNSATAPSTLTDVNDAGRVVGMD
                     AGVPKEWLNGKVVRELPVPADAHPSTKIISVDGINKRGDIVGTALTYYWEDDVVTSKSF
                     PVVWPAGGGYPPYSLRVWTDSDYTVGTRATGIDDLGRVVGHEDRSYRDWQERKPAAWKK
                     PYDALPADPGRVGGFEHLTLDAISPTTNVSVGTAVTFVEGYANHIQAAYWPGKGSPLAL
                     PHPAGAAPDSRSEAFAASDDDRVGGTFYDWNTMTASAVVWTCASGQAYAPKA"
     misc_feature    1335..1349
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.08"
                     /tool="antismash"
     misc_feature    1396..1411
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     gene            1607..2593
                     /locus_tag="IE248_RS10965"
                     /old_locus_tag="GCM10010336_22290"
     CDS             1607..2593
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0003960 - NADPH:quinone reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_function="GO:0070402 - NADPH binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (13-318). E-value: 5.4e-50.
                     Score: 162.2. Matches aSDomain:
                     nrpspksdomains_IE248_RS10965_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267929.1"
                     /locus_tag="IE248_RS10965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22290"
                     /product="NADPH:quinone oxidoreductase family protein"
                     /protein_id="WP_047960797.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.1e-28, bitscore:
                     95.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAWRVHTPGEPIEAMRLEEVPEPVPGEGEVRLKVLAANVNFPDA
                     LLARGQYQIRPPLPFTPGVEICGETEDGRRVIANPSLPHGGFAEYVTAPARALLPAPDT
                     LDDAEAAALHIGYQTGWFGLHRRARLQSGETLLVHAAAGGVGSAAVQLGKAAGATVIGV
                     VGGKAKARTAEELGCDLVIDRTADDTAQVAARVKEFTGGRGADVVYDPVGGEAYTASAK
                     CVAFEGRIVVVGFASGTVPAPALNHALVKNYAVLGLHWGLYAAKDPAAVLACHTELTRL
                     AAEGAVKPLVTERIPLAGAADAVQRLADGTTAGRLVVVPALDGGGSR"
     aSDomain        1646..2560
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10965_PKS_ER.1"
                     /evalue="5.40E-50"
                     /label="IE248_RS10965_PKS_ER.1"
                     /locus_tag="IE248_RS10965"
                     /protein_end="318"
                     /protein_start="13"
                     /score="162.2"
                     /tool="antismash"
                     /translation="EAMRLEEVPEPVPGEGEVRLKVLAANVNFPDALLARGQYQIRPPL
                     PFTPGVEICGETEDGRRVIANPSLPHGGFAEYVTAPARALLPAPDTLDDAEAAALHIGY
                     QTGWFGLHRRARLQSGETLLVHAAAGGVGSAAVQLGKAAGATVIGVVGGKAKARTAEEL
                     GCDLVIDRTADDTAQVAARVKEFTGGRGADVVYDPVGGEAYTASAKCVAFEGRIVVVGF
                     ASGTVPAPALNHALVKNYAVLGLHWGLYAAKDPAAVLACHTELTRLAAEGAVKPLVTER
                     IPLAGAADAVQRLADGTTAGRLVV"
     CDS_motif       2003..2062
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10965_0001"
                     /evalue="7.20E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE248_RS10965"
                     /protein_end="152"
                     /protein_start="132"
                     /score="24.8"
                     /tool="antismash"
                     /translation="GETLLVHAAAGGVGSAAVQL"
     gene            2590..3777
                     /locus_tag="IE248_RS10970"
                     /old_locus_tag="GCM10010336_22300"
     CDS             2590..3777
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005307789.1"
                     /locus_tag="IE248_RS10970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22300"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_190030610.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.5e-12, bitscore:
                     43.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.5e-22, bitscore:
                     73.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.5e-21, bitscore:
                     71.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEELLARVRDLLAAHPPGESDRTDFLRARFDAGLAWVHYPEG
                     LGGLGAPRSLQAVVDAELEAAGAPGNDPRRIGIGLGMAAPTILAYGTAEQKHRFLRPLW
                     VGEEVWCQLFSEPGAGSDLAALATRAVREEDSGDWIVDGQKVWTSSAHTARWAILIART
                     DPALPKHRGITYFLCDMHAPGVEVRPLRQITGEAEFNEVFLTGVRIPDAHRLGAVGQGW
                     EVARTTLMNERVSIGGMRIPREGGMIGPVSAVWRERPELRTHALHQRLLELWVEAEVAR
                     LTGERLRQQLAAGQPGPEGSGMKLTFARLNQEISGLEVELLGAEGLLYEDWTMRRPEIV
                     DFTGRDAGYRYLRAKGNSIEGGTSEVLLNIVAERVLGLPAEPRDDKDTAWKDLAR"
     gene            3774..4922
                     /locus_tag="IE248_RS10975"
                     /old_locus_tag="GCM10010336_22310"
     CDS             3774..4922
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523251.1"
                     /locus_tag="IE248_RS10975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22310"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_100580936.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.7e-13, bitscore:
                     45.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.6e-28, bitscore:
                     94.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDETERTTPMASHAPFDLLYSETEEELRSAVRALLADRCDAASV
                     LARAETDRPYDPELWSTLAGGIGAAGLLVPEKLGGQGASHREAAVVLEELGRAVAPAPY
                     LTSAVLATEILLGCDTTSAEVAGLLAQVAAGARVCVPAVPLTLAPGAPLPSGVRDAGGG
                     VLTGSAGPVADAVAADVLLVLADTGLYAVPAAAVTLVRAVPLDLTRPLATVELDGATGT
                     RLGDPATARAAVAGALLSGAGLLASEQLGIAQWCLTETVAHVRARHQFNRPVGSFQALK
                     HRLARLWLDVASARAAARAAADALATGSPDAPLTVAVAQAYCSGVAVRAAEECVQLHGG
                     IGMTWEHPAHLYLKRAKADALALGSAGHHRTLVADFAELPSP"
     misc_feature    complement(4994..5007)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.17"
                     /tool="antismash"
     gene            5001..5375
                     /locus_tag="IE248_RS10980"
                     /old_locus_tag="GCM10010336_22320"
     CDS             5001..5375
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0042438 - melanin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116481.1"
                     /locus_tag="IE248_RS10980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22320"
                     /product="tyrosinase family oxidase copper chaperone"
                     /protein_id="WP_190030611.1"
                     /sec_met_domain="melC (E-value: 3e-44, bitscore: 145.9,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAAPAAAPLTRRAVLRTAFTAAVLAGTAAALAPVLRARRPRQTL
                     TPAPFAEETYRGRHIAVELAGTAVRIDGRPLHVMRRADGSYLSGINHFQSFATPLELAR
                     AAVDELGTTQLAPAAPHHGG"
     gene            5402..6262
                     /locus_tag="IE248_RS10985"
                     /old_locus_tag="GCM10010336_22330"
     CDS             5402..6262
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267933.1"
                     /locus_tag="IE248_RS10985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22330"
                     /product="tyrosinase family protein"
                     /protein_id="WP_100580934.1"
                     /transl_table=11
                     /translation="MYTRQNQKNLTSTQKRRFTAAVLELKRNGTYDRFVRTHDKYFVPD
                     RDRGLRVGHMSPSFFPWHRRYLVEFEKELRALDPGVSIPYWDWTTDTSPVSSLWAEDFL
                     GGTGRSSDRQVMTGPFAYARGDWTITVGITEARYLTRNLGRPQNPVTLPTPAELQWAID
                     DPTYDASPWDSTAGGFRNRLEGWAAPKSERWRNHNKVHQWIGGHMTGGTAPNDPVFWLH
                     HAFVDLLWDRWQQRHPSSGYRPATAPLPGDAQRGRVIALDEPMPPWNISPREMLGHQGV
                     YRYEV"
     gene            complement(6334..6627)
                     /locus_tag="IE248_RS10990"
                     /old_locus_tag="GCM10010336_22340"
     CDS             complement(6334..6627)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116479.1"
                     /locus_tag="IE248_RS10990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22340"
                     /product="chaplin"
                     /protein_id="WP_100580933.1"
                     /transl_table=11
                     /translation="MSRIAKAFAITAVAGSAVAAGAGLAVADAGAQGAAIGSPGVLSGN
                     LVQVPVHVPVNVCGNSVNIVGLLNPAFGNTCVNASGGGTATTQQQHTEGYGG"
     misc_feature    complement(6674..6684)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(6724..7095)
                     /locus_tag="IE248_RS10995"
                     /old_locus_tag="GCM10010336_22350"
     CDS             complement(6724..7095)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE248_RS10995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010336_22350"
                     /product="hypothetical protein"
                     /protein_id="WP_190030612.1"
                     /transl_table=11
                     /translation="MRDTRILLRTGAVPALLLAAAAVAAVTATATAAPAAGGTAPAGAA
                     GPDFQYVGQDDRVHGLTAPKGCVAAEGGGSRPVTNHTRGTATFYREPGCAGAPVERLGP
                     GTVTQVRPYFASVRFSVTG"
     gene            7218..8675
                     /locus_tag="IE248_RS11000"
                     /old_locus_tag="GCM10010336_22360"
     CDS             7218..8675
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376916.1"
                     /locus_tag="IE248_RS11000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22360"
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="WP_190030613.1"
                     /transl_table=11
                     /translation="MRAPSGRPRAGTGYGVVEGRREAGGIAVFRGIPYAAPPVGALRFA
                     APAPPEPWEGVRDAGAFGPTAPKVPYPDTFAALLPDPEIPGDDCLNLNVWTPDPDPGAR
                     LPVMVWIHGGALTRGSAAVPVYDGAAFARDGVVLVSFNYRLGALGYGLFPDAPANRGLL
                     DQIAALTWVRDNIEAFGGDPGRVTVFGESAGAISIGALLAAPRAAGLFTRAVLQSGAPE
                     VLPRDRVRTMVRRMAALLKVPATAGAFTAVALPDLLRAQAAVLRRTNSLVGGPAFGLVA
                     DPATLPDDPLEAAAAGEVPLLLGWTAEEYRLWLAPTGAMRVLDRLGPLAVSLARARSGK
                     DRATVRTLRTALPGASAAELAGQLLTDRLLRDPLRRLAGARRSAPSHLYEFRWRSGVPG
                     LGSCHALELGFVFDTLHVPEAAWLAGRDTPQELADEMHAAWVRFAVTGDPGWAPWDGSG
                     PPKVFGGPEREGEGAGEALAATPPVLP"
     gene            complement(8653..9984)
                     /locus_tag="IE248_RS11005"
                     /old_locus_tag="GCM10010336_22370"
     CDS             complement(8653..9984)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984259.1"
                     /locus_tag="IE248_RS11005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22370"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_373301506.1"
                     /sec_met_domain="PF00561 (E-value: 2.6e-06, bitscore: 22.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYAPDGQQQYQPYRPAPEGQYRQPRPPHDGPPPGPPYGQGQGYG
                     QGQGYGQAQGQGYGQEGQGYGQGPGPDQGYGHEYDYGPPQPPEEPRRRSRGKRWLIAGV
                     AVLGLAGIAAGVMYHFEIPPFTDKGSAVSFGQPAAGGGGGGGAAKQAPNSKMLMPTGPA
                     ADFKNAQTLPDGTHIAVTTLDGKKSGFKGKVWVWAPKEYNDPKFAKSGFPVLIALPGGA
                     GYPNNYWMGTDLGLQSSISKWYAEGKSKPFILAMPVLNPGPDDKGVYWDGSDIPGQPKM
                     GTWLTDDVPDLMKANFRTIKSRDGWAFMGSSTGGFAGMKAVLKYPDRFKAVVASGPDIV
                     PDSSLWKGHDKEKAENNPELLAKDLIDKKGPDVYIAFQVGDSESNKRTLPDVQKFIATY
                     GNKGPVHTSLKVIPGGKHNAKTYVPNMGEGPIEFISKVMEGPVE"
     misc_feature    10053..10066
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            10250..11131
                     /locus_tag="IE248_RS11010"
                     /old_locus_tag="GCM10010336_22390"
     CDS             10250..11131
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672330.1"
                     /locus_tag="IE248_RS11010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22390"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_047960799.1"
                     /transl_table=11
                     /translation="MSRSQVSRKTALAAAFGVTAAGAALWAGIGAAQPAHAAGLPAPDH
                     VVVVVFENHAYNQVIGSSSAPYLNSLKTGGANLTNSFGITHPSQPNYLQLFSGSHQGVT
                     GDSCYTPGFSSAPNLASELIAAGKTWASYNETLPSQGSTTCSSGNYARKHNPWFAFSNV
                     PTSTAKTMTQFPADFTTLPKVSFVVPNLCNDMHDCSVGTGDTWLKNNLKAYADWAKTHN
                     SLLVVTFDEDNRLAGNKIPTVLYGQPVTPGSTSSTTYNHYDVLRTLEGLAGLTTHAGNA
                     AGAKDITGIWAS"
     gene            11134..12399
                     /locus_tag="IE248_RS11015"
                     /old_locus_tag="GCM10010336_22400"
     CDS             11134..12399
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556955.1"
                     /locus_tag="IE248_RS11015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22400"
                     /product="MFS transporter"
                     /protein_id="WP_190030614.1"
                     /transl_table=11
                     /translation="MYVADSRGTPAPAVTPESPAVAPGTSPGRRAALAPTVLALGTVSL
                     ITDVSSEMVTAVLPLYLVAGLGLSPLGFGLLDGLYNGVSALVRLTGGHLGDRLGRHKAL
                     AGIGYGLSALCKPLLLLVHTLPAIGAVLALDRTGKGLRTAPRDALISLSAAPADRGRAF
                     GVHRAMDTAGALIGPILAFLILRGAADGYDAVFTVSACVAALGVLVLVLFVPGRRTTAA
                     PGAEPVSLRASVGLLRRRDLRRISLCALLLGLCTVSDGFVFLLLQRATGIADRWFALLP
                     LGTAAAFFLLALPLGRLADRIGRRRVFLGGHLALLLLYGLLLVGGQHPALPYAVLLLHG
                     GFYAATDGVLMAAAAGTVPEEHRGAGLALVQTGQALARFAASLGFGAVWTVWGPRPALA
                     VAAALLAVAAALCVRLRPGADA"
     misc_feature    complement(11173..11188)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            12422..13450
                     /locus_tag="IE248_RS11020"
                     /old_locus_tag="GCM10010336_22410"
     CDS             12422..13450
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672332.1"
                     /locus_tag="IE248_RS11020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22410"
                     /product="hypothetical protein"
                     /protein_id="WP_073798564.1"
                     /transl_table=11
                     /translation="MTLQRRILILVCAAALLAAVGALAVVRASSRADEKNQARAGGPRI
                     TRGEVSLTPGDGGRRIVFRNMAWGPHRDELATVPAGEPEGPRTASGVTCLRFHSAAGTG
                     VCLQADKGGVQESYRAVVLDARLKEVSAHPLAGIPTRARVSPGGHLAAWTVFVGGDSYA
                     GTNFSTRTSVLDLRTGRYDASLEDFTIRKDGKTYRNADVNFWGVTFTADERGFYATLAT
                     GGKTYLVRGDLAGRTVTTLRENLECPSLSPDGTRLVFKKRVEGAPAEAPWRLYALDLAT
                     MRETPLAEERSVDDQVVWTDDKTVVYSLPGDFGADLYAVPADGSGAPARLMDSALAPAF
                     LG"
     gene            complement(13491..14177)
                     /locus_tag="IE248_RS11025"
                     /old_locus_tag="GCM10010336_22420"
     CDS             complement(13491..14177)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267942.1"
                     /locus_tag="IE248_RS11025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22420"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073798565.1"
                     /transl_table=11
                     /translation="MPVPVLLAGRSVRLEPLAPHHTEALAMAGAEDRTTYAFTPVPHGV
                     QASHEYIDRALADQAAGRSLPFAVVRATDGRVVGSTRFLELDYWQGPLVWPAVPGVPFG
                     DPATAIPDAAEIGNTWLSPAAQGTGINTEAKLLMLRHAFETWGVRRISLRADARNGRSR
                     AAMERLGFTCEGVRRAHSRGLDGAVRSTAFYSILDEEWPTVRSIIELRLSSAAQRKRRR
                     KTLIPA"
     misc_feature    complement(14298..14315)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    14341..14356
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.93"
                     /tool="antismash"
     misc_feature    14349..14358
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    complement(14753..14764)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            14759..15439
                     /locus_tag="IE248_RS11030"
                     /old_locus_tag="GCM10010336_22430"
     CDS             14759..15439
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267945.1"
                     /locus_tag="IE248_RS11030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22430"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_190030615.1"
                     /transl_table=11
                     /translation="MDMDDVLRRLASVGPFFTVPYGKEPPGPGFRPLGDLYGERLGPYV
                     TEVGRRIRSGPGRVAASTAQLGIASRLWSLGLGCAALGGRVPDLGVDRVWWRLPAAGSL
                     ELWLPEPETGALDAGALGENVLGNLGVLDAGLRERFGVSAKALRGNTASGLVGALRVLL
                     DRVPGGPAVSLAADLLADGGALGGAGTFLYEEGLGVAFVRRSCCLYYQVPGGGLCGDCV
                     LRTR"
     gene            complement(15584..17356)
                     /locus_tag="IE248_RS11035"
                     /old_locus_tag="GCM10010336_22440"
     CDS             complement(15584..17356)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123169.1"
                     /locus_tag="IE248_RS11035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22440"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_047960801.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 8.8e-42, bitscore:
                     138.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAATLGAALAFGAPAALAGTAPVSPSGAPAPVAKAPGGAKAAAP
                     SSQSATWVAGTRAYLVITAPGDSSAVRSAIAANGGTVFSNYDAIGVIVAHSASSTFATT
                     MRGVSGVQKVGATRTSDVPADAYNPALPANPAQSSTPAGEPVRADMSQIKADQAWAVTT
                     GSASVKVGVLDTGVDDQHQDLAPNFNAADSVSCAYGKADARTGAWRDVDTHGTHVAGTI
                     AAAKNGKGVVGVAPGVKISAVRVAEPGNSFFFAENTICGFVWAGDHGFKVTNNSYYTDP
                     WQFNCPDNIDQAAIIEGVKRAQEYAESKGSLQIAAAGNENYDLAHKTTDTASPNDSTPV
                     TRTITNACLDIPTELPGVVTVAANGSGTTKASFSNFGSGVIDVAAPGSDVYSTLPGGKY
                     GTKSGTSMATPHVVGVAALIASANPGITPAQIRDKLATQANDIACPSDSRCTGTAANNS
                     FFGEGQVDALKAVGSTPPSGKYFENLGDVAIGDNTTVESPITVSGVSGNAPATLKVGVD
                     IKHTYIGDLKVDLVAPDGTVYTVHNRAGGGTDNIAQTYTVNASSEVANGTWKLRVNDNA
                     GGDTGKIDAWNLTF"
     gene            complement(17573..18943)
                     /locus_tag="IE248_RS11040"
                     /old_locus_tag="GCM10010336_22450"
     CDS             complement(17573..18943)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087322.1"
                     /locus_tag="IE248_RS11040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22450"
                     /product="cation:dicarboxylate symporter family
                     transporter"
                     /protein_id="WP_073798567.1"
                     /transl_table=11
                     /translation="MAARRDKTHYLYIAVIGAVLLGIAVGFAAPGVAVELKPLGTGFVN
                     LIKMMISPVIFCTIVLGIGSVRKAAKVGAVGGLALGYFMIMSTVALAIGLLVGNLLEPG
                     SGLHLTEAARHAGEAQAKAGGAQSTPEFLLAIIPTTMVSAFTGGQVLQTLLVALLCGFA
                     LQAMGPAGEPLLRGIGHVQKLVFRVLAMIMWAAPVGAFGAIAAVVGATGIDALKSLAVI
                     MIGFYTTCLLFVIVVLGTLLRVCTGVSVFALLRYLGREFLLILSTSSSESALPRLIAKM
                     EHLGVSKPVVGITVPTGYSFNLDGTAIYLTMSSLFIAEAMDKPLAIGEQISLLLFMIVA
                     SKGAAGVTGAGLATLAGGLQSHRPELVDGVGLIVGIDRFMSEARALTNFAGNAVATVLI
                     GTWTKEFDRDRAAEVLAGRCPFDETTLVEDTHGDQADDGAATPVPAQPATPKDGVPA"
     misc_feature    complement(18991..19006)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            19049..20815
                     /locus_tag="IE248_RS11050"
                     /old_locus_tag="GCM10010336_22460"
     CDS             19049..20815
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521210.1"
                     /locus_tag="IE248_RS11050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22460"
                     /product="sensor histidine kinase"
                     /protein_id="WP_229895249.1"
                     /transl_table=11
                     /translation="MFRLPRPPRSLAGQLFAMQVLVVAVIVAGCAVFAYATARGQAEDA
                     ARRQAGAVARSVADSPSVREAVREAAPGTAPAAGLPTGSATGAPASSATRSATSPATGS
                     ATGPATGPATRSATGPATGSAVDAFAALSAELQPYAERVRTDSGVDFVTIMAPDGRRWT
                     HPDPRRIGERFIGNTAPALRGETFSETYTGTLGPSIRVVTPLSDNGRVIGMVSAGITVR
                     VIGDRLAAQLVVLGWFAAGALALGGAGTYVVNARLRRHTHGMNAAELSRMYDYHQAALH
                     GVREGLLMLDGQRRITLINDAGRELLGLEGKIRGTGVADLGLPAPLTGALLADGPRVDE
                     VHLTADRVLVVNSSPVAGGGRKGTVVTLRDHTELQSLTGELDHERGFTQALRSQAHEAA
                     NRLHTVVSLIELDRAEEAVEFATAELELAQALTDEVVTAVGEPVLVALLLGKAAQAHER
                     GVELVVTPDSSVIDGRTGIPPARDLVTVLGNLVDNAVDALSGVPGGRVMVTVRAEGDGL
                     LIRVADNGPGLPEGADVFRRGWSGKGEGRGLGLALVRQVAHRHGGSADAGARAEGGAEF
                     TVRLPTRGEAGA"
     gene            20812..21513
                     /locus_tag="IE248_RS11055"
                     /old_locus_tag="GCM10010336_22470"
     CDS             20812..21513
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267949.1"
                     /locus_tag="IE248_RS11055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22470"
                     /product="response regulator"
                     /protein_id="WP_037798776.1"
                     /transl_table=11
                     /translation="MSAPEVRVLIVEDDPVAAAAHALYVGRVPGFTAVGAVHSLAEATR
                     VLERTGVDLLLLDLTLPDGHGLRFARGLRAAGHPVDVIVVTSARDLAVVRESVSVGVVQ
                     YVLKPFAFPTLRERLLRYAEFRATAGEAAGQDDVDRALAALRAPRPAELPKGLSAPTLD
                     RVAALLRAAPEGLTAAGAAEAAGISRITARRYLEHLVDTGRADRTPRYGQVGRPELHYR
                     WLAAAGSVSKV"
     gene            complement(21471..22316)
                     /locus_tag="IE248_RS11060"
                     /old_locus_tag="GCM10010336_22480"
     CDS             complement(21471..22316)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267950.1"
                     /locus_tag="IE248_RS11060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22480"
                     /product="tyrosinase family protein"
                     /protein_id="WP_037798777.1"
                     /transl_table=11
                     /translation="MTVRKNQATLSAEEKRAFTNALIELKRTGAYDRFVTTHNGFIMSD
                     TDSGDRVGHRSPSFLPWHRRFLLEFEAALQTVDAKVTIPYWDWSADRTTRSSLWAADFL
                     GGTGRARDGQVTDGPFAYATGKWDINVRVDGRNYLRRALGAGVAELPTKAEVDAVLSMP
                     VYDMAPWNSSSNGFRNNLEGWRGANLHNRVHVWVGGQMATGVSPNDPVFWMHHAFVDKL
                     WADWQARNPRSTYLPAAGTSNVVDLHDTMRPWNNVTPADMLDHRKFYTFDTEPAAASQR
                     "
     gene            complement(22313..22708)
                     /locus_tag="IE248_RS11065"
                     /old_locus_tag="GCM10010336_22490"
     CDS             complement(22313..22708)
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0042438 - melanin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644282.1"
                     /locus_tag="IE248_RS11065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22490"
                     /product="tyrosinase family oxidase copper chaperone"
                     /protein_id="WP_037798778.1"
                     /sec_met_domain="melC (E-value: 2.1e-47, bitscore: 156.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKITRRQALGTTAGTLSALGLLGAAAHSATAASPAPAAPAGTVD
                     EVFQGRRIQISPATGGGHHGGHHGSDLPTVRIDGRELHVMRNADGTWISVVNHYETFAD
                     PTSLARAAVRELQGAQLAPFAPMGGAA"
     misc_feature    22740..22753
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     misc_feature    22834..22849
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     gene            22964..24355
                     /locus_tag="IE248_RS11070"
                     /old_locus_tag="GCM10010336_22500"
     CDS             22964..24355
                     /EC_number="4.1.1.15"
                     /GO_function="GO:0004351 - glutamate decarboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0006540 - glutamate decarboxylation to
                     succinate [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018836423.1"
                     /locus_tag="IE248_RS11070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22500"
                     /product="glutamate decarboxylase"
                     /protein_id="WP_037798780.1"
                     /transl_table=11
                     /translation="MALHETKDVPAQDADTDVFTSALSGEILPKYRMPEDHSPSEVVYE
                     LLHNELLLDGNAAQNLATFCTTWSDDGVRRLMAECLDKNMIDKDEYPQTAEIESRCVNI
                     LADLWNAPSGGAATGCSTTGSSEAAMLGGLALKWRWRERRRAAGLPVDRPNLICGPVQI
                     CWDKFARYFDVELRQIPLEPGATGLRPHQLAQYVDENTIGVVAILGVTYSCDYEPVAEI
                     CAELDRIQAEHGWDVPVHVDAASGGFVAPFLHPDVVWDFRLPRVASVNTSGHKYGLAPL
                     GVGWIVWRTADLLPADLVFNVDYLGGDMPTFALNFSRPGGEVIAQYYLFLRLGRGGYRR
                     VQLACAETAQYLAQEIAAMGPFTLLYDGRGGLPAVSYTLADPEGSPFTLYDLSDRLRMR
                     GWQVPSYALPADRDDTVIQRVLIRHGVTRDQIALLASDLRKAVEHLTATPPPVPATEPR
                     SGFHH"
     gene            complement(24359..26842)
                     /locus_tag="IE248_RS11075"
                     /old_locus_tag="GCM10010336_22510"
     CDS             complement(24359..26842)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988963.1"
                     /locus_tag="IE248_RS11075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_22510"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_190030616.1"
                     /transl_table=11
                     /translation="MARKELRPHQREAVDAVARALELPAGGRVPQAGLRTQVIMATGSG
                     KSLVAVRSAQELRAARVLVLVPTLDLLVQTAAAWREGGRAGRRLAVCSLREDDAGMPTT
                     TDPAELARRGGRVADRVTVFATYASLGMGTIERAHLAGLPAWDLIVVDEAHRTSGRIGK
                     PWAVVHDNARIPALRRLYMTATPRVWQDGEPPEEGGESGEDGADDGGRGRSGLVASMED
                     DPAGPFGARCHTLTLSEAIDRGICAPYRVVCVDVTDPGFQAAVLLGPDGRSDAVRGSRL
                     AALQTALVKAAADQGFRRTLVFHHLTREAEAFAAGLPAVARRLRSARPPGGAPGRSAGG
                     ARPGAGEPKGPVYPRTVWADWLCGLHPPAHRRRVLAEFASGQAAEKAFLGSVRVLGEGV
                     DIAECDSVYWADVRGSMPDLVQAVGRALRIRPGEGKVASLVVPVLLGPGETPESMLTSR
                     AYGSLARLLEALRAHDTRLVEALAQPQAPGRPAGAPGAGSAAESLLSFATPRDPALLAA
                     FVRLRVLNPEHEHWRRGVEAARIYAEGAGDLKVPFAHRVPAGASPWPPGLAGFPLGQWI
                     ADARRTYRRGALGRERVAELDRLGMVWSHFDVAFEEGLQAARAWAAEHGHLLPPADATW
                     NGAPVGIWVKNQRAAARREGAGALSQERREALEEIDAAWCPAWPVSWQRAFHLTRVHLD
                     AGGRLPAGPGEVLVQGEDLGLWLRSQRLSWERLSWAQRWLLEHTLGAAPATGAELPPPR
                     VAHAAAWAAHLEAARRFHERERHLRVPRTHVERVGGREFKLGSWIANQRSRAASLTPER
                     VEALTALGMRWSASA"
ORIGIN
        1 gggcagggcg gcggcgccga gcgccggcgg cgcgggcagc ccgcgcgcgg ggtgctgtgc
       61 ggggtcctgc gcggggtgcc gtgaagggtt ctccatgcgg catcgatacc gcgcgggcgc
      121 tcagatggcc atggccgcgc ccccgcggaa ccccgtcccc gctcgccgcc ccgctacgcc
      181 ttcggcgcgt acgcctgtcc gctcgcgcag gtccacacga cggcgctggc cgtcatcgtg
      241 ttccagtcgt agaaggtgcc gcccacccgg tcgtcgtccg acgcggcgaa ggcctcgctg
      301 cgcgagtccg gcgcggcgcc cgccgggtgg ggcagcgcca gcggggagcc cttgcccggc
      361 cagtacgcgg cctggatgtg gttggcgtag ccctcgacga aggtgacggc ggtgccgacg
      421 ctcacgttcg tggtcgggct gatggcgtcg agcgtgaggt gctcgaagcc cccgacccgg
      481 cccgggtctg ccgggagcgc gtcgtacggc ttcttccagg cggcgggctt gcgctcctgc
      541 cagtcacggt agctgcggtc ctcgtgcccg acgacccggc ccaggtcgtc gatgccggtc
      601 gcgcgcgtgc ccaccgtgta gtccgagtcg gtccagaccc gcaggctgta cggcgggtag
      661 ccgccgccgg cgggccagac gacggggaag ctcttgctcg tgacgacgtc gtcctcccag
      721 tagtaggtga gggcggtgcc gacgatgtcg ccgcgcttgt tgatcccgtc caccgagatg
      781 atcttggtgg aggggtgtgc gtccgccggc acgggcagct cgcgcaccac cttgccgttc
      841 agccactcct tcgggacgcc cgcgtccatg ccgacgaccc ggccggcgtc gttgacgtcc
      901 gtcagggtgc tcggcgcggt ggcggagttg accagtgcga ccgccgccgc gccctgctgg
      961 taggtgaagg cgaagctgtg gtcgtagtcg cccggccggc ggagcgcgcc gaccatcagg
     1021 cccttggcgt tcacggcctt gacctcgccg gactggaagc cctcgggcac cggtaccgcg
     1081 tgcgccgtgc cgtccgccgt ccagtacgcc ggcaggccgc ggctctgacc ggcgatcagg
     1141 ccgttcgcgc cgaaggcctt gaccgtcccg ccgttcccgg cgccggcggg cccggccgcg
     1201 atgtcggcca gcttgacgac ggccggtgcg cacgcctttg cggccgccgg gcccggcgcg
     1261 gccgcggcgg ccgggccggc cgccgtgatc aggcccgcca gagcgatcgc ggcggcggtc
     1321 gcggctccgg ccgcggacat gctgttcctc atgtggacgt cccccctgga catgtgctgt
     1381 tccccgttga gtcatgacac gtgcacgtca catgctgcct caggagcggc gcgagtggcg
     1441 cgattgacgc gggttgtttt cgggccccgg gtgggcaggt cctctgccgg gcccctccgc
     1501 tccgcctccc gaaggctccc ggggcctccc gacggttccc aatcaggcaa gcgaccgctt
     1561 agtatgcggc cgagcgtggt tcctcgacgg cggctggagg ccccggatgc aggcatggcg
     1621 agtacacacc cccggcgaac ccatcgaggc catgcgcctc gaagaggtcc ccgaaccggt
     1681 ccccggcgag ggggaggtga ggctgaaggt gctcgcggcg aacgtcaact ttcccgacgc
     1741 gctgctcgcc cgcggccagt accagatccg gcccccgctg cccttcaccc ccggggtgga
     1801 gatctgcggc gagaccgagg acggccgccg cgtcatcgcc aacccgagcc tgccgcacgg
     1861 cggtttcgcc gagtacgtca ccgcccccgc gcgcgccctg ctgcccgccc ccgacaccct
     1921 cgacgacgcc gaggcggccg ctctgcacat cggctaccag accggctggt tcggcctgca
     1981 ccgccgcgcc cgcctccagt ccggcgagac cctgctcgtc cacgccgccg cgggcggggt
     2041 cggcagcgcc gcggtccagc tcggcaaggc cgccggggcc accgtcatcg gggtcgtcgg
     2101 cggcaaggcc aaggcccgga ccgccgagga actcggctgc gacctggtca tcgaccgcac
     2161 cgccgacgac accgcccagg tcgccgcccg cgtcaaggag ttcaccggcg gacgcggcgc
     2221 cgacgtggtc tacgacccgg tcggcggcga ggcctacacc gcctccgcca aatgcgtggc
     2281 cttcgagggc cggatcgtcg tcgtcggctt cgccagcggc accgtccccg cgcccgccct
     2341 caaccacgcc ctcgtcaaga actacgccgt gctcggcctg cactgggggc tctacgccgc
     2401 gaaggacccc gccgccgtcc tcgcctgcca caccgagctc acccggctcg ccgccgaggg
     2461 cgccgtgaaa ccgctcgtca ccgaacggat cccgctcgcc ggggccgcgg acgccgtgca
     2521 gcgcctcgcc gacgggacca ccgccggccg gctggtcgtc gtaccggccc tggacggagg
     2581 cggctcgcga tgatcacctc cgaggaactg ctcgcgcgcg tacgggacct gctcgccgcc
     2641 cacccgcccg gcgagagcga ccgcaccgac ttcctgcggg cccgcttcga cgccggactc
     2701 gcctgggtcc actaccccga gggcctcggc ggcctcggcg ccccgcgctc cctccaggcc
     2761 gtcgtcgacg ccgagctgga ggccgccggc gcccccggca acgacccgcg ccggatcggc
     2821 atcggcctcg gcatggccgc gccgacgatc ctcgcctacg gcaccgcgga gcagaagcac
     2881 cgcttcctgc ggcccctgtg ggtgggggag gaggtctggt gccagctgtt cagcgaaccc
     2941 ggcgccggct ccgacctcgc cgcgctcgcc acccgcgcgg tccgcgagga ggactccggc
     3001 gactggatcg tcgacgggca gaaggtgtgg acctccagcg cccacaccgc ccgctgggcc
     3061 atcctgatcg cccgcaccga tccggctctg cccaagcacc ggggcatcac gtacttcctg
     3121 tgcgacatgc acgcccccgg cgtcgaggtc cggccgctgc gccagatcac cggcgaggcc
     3181 gagttcaacg aggtcttcct caccggcgtc cggatccccg acgcccaccg cctcggcgcc
     3241 gtcggccagg gctgggaggt cgcccgcacc accctgatga acgaacgcgt ctccatcggc
     3301 ggcatgcgga tcccgcgcga gggcggcatg atcggccccg tctccgcggt ctggcgcgag
     3361 cgccccgaac tgcgcacgca cgcgctgcac cagcgcctgc tggaactgtg ggtggaggcc
     3421 gaggtggccc ggctgaccgg ggaacggctg cgccagcagc tcgccgcggg ccagcccggc
     3481 cccgagggct cggggatgaa gctgaccttc gcccgcctga accaggagat cagcggcctg
     3541 gaagtggaac tcctcggcgc ggaaggcctg ctgtacgagg actggacgat gcgccggccc
     3601 gagatcgtcg acttcaccgg ccgcgacgcc ggctaccgct acctgcgcgc caagggcaac
     3661 agcatcgagg gcggcaccag cgaggtcctc ctcaacatcg tcgccgagcg ggtcctcggg
     3721 ctgcccgccg aaccgcgcga cgacaaggac accgcctgga aggacctggc ccgatgacgg
     3781 acgagacgga gcggacgacc ccgatggcct cgcatgcccc cttcgacctg ctgtactccg
     3841 agaccgagga ggagctccgg tcggccgtac gggcgctcct cgccgaccgc tgcgacgccg
     3901 cgagcgtgct cgcccgggcc gagaccgacc ggccctacga cccggagctg tggagcaccc
     3961 tcgcgggcgg gatcggggct gccggactgc tcgtcccgga gaagctcggc gggcagggcg
     4021 cgagccaccg ggaggcggcc gtggtcctgg aggaactggg ccgggccgtc gcgcccgccc
     4081 cgtacctgac cagcgccgtc ctggcgacgg agatcctgct cggctgcgac acgacctcgg
     4141 ccgaggtggc cgggctgctg gcgcaggtgg cggcgggcgc gcgggtctgc gtgcccgccg
     4201 tgccgctgac gctggcgccg ggggccccgc tgccctccgg ggtgcgcgac gccgggggcg
     4261 gggtcctgac ggggagcgcc ggcccggtcg cggacgccgt ggccgccgac gtgctgctgg
     4321 tgctggcgga caccgggctg tacgcggtcc cggccgcagc ggtcacgctc gtacgggcgg
     4381 tcccgctgga cctgacccgg ccgctggcca ccgtggagct ggacggggcc accggaaccc
     4441 ggctcgggga cccggccacc gcgcgggcgg cggtcgcggg ggcgctgctg tcgggggcgg
     4501 ggctgctggc gtccgagcag ctcggcatcg cgcagtggtg cctgacggag acggtcgccc
     4561 acgtacgggc ccgccaccag ttcaaccggc ccgtcggatc cttccaggcc ctcaaacacc
     4621 ggctggcccg gctctggctc gacgtggcct cggcccgcgc ggcggcgcgg gccgccgcgg
     4681 acgcgctcgc caccggctcc ccggacgctc cgctgacggt cgcggtggcc caggcgtact
     4741 gctcgggcgt ggccgtccgg gccgcggagg agtgcgtgca actgcacggc ggcatcggca
     4801 tgacctggga acacccggcg cacctgtacc tgaagcgagc caaggccgac gccctggccc
     4861 tgggctccgc cggccaccac cgcaccctgg tggcggactt cgcggaactc ccgtccccgt
     4921 agccggggcc ccgacggggt gacctcgttc gctggtccgc gttagtcccc gtacgcggac
     4981 caccgagcga gggagaccgt atgttcgcag caccggccgc cgcaccactc acccgccgcg
     5041 cggtcctccg tacggccttc accgccgccg tgctggccgg gacggccgcc gcgctggccc
     5101 cggtactgcg ggcccggcgg ccccggcaga cgctcacccc ggcgccgttc gccgaggaga
     5161 cgtaccgcgg ccggcacatc gccgtcgagc tcgccgggac ggccgtgcgc atcgacgggc
     5221 gcccgctgca cgtgatgcgc cgcgccgacg gcagctacct cagcggcatc aaccacttcc
     5281 agtcgttcgc gacgccgctg gagctggccc gcgccgccgt cgacgaactg ggcaccaccc
     5341 agctggcccc cgccgccccc caccacggcg gctgacgcac gggaacggga ggagccccga
     5401 ggtgtacacc cggcagaacc agaagaacct gaccagcacc cagaagaggc ggttcaccgc
     5461 cgccgtcctg gaactcaagc gcaacgggac ctacgaccgg ttcgtgcgca cccacgacaa
     5521 gtacttcgtg cccgaccggg accgggggct ccgggtgggc cacatgtccc cgtcgttctt
     5581 cccctggcac cgccgctacc tcgtggagtt cgagaaggag ctccgggcgc tcgaccccgg
     5641 cgtcagcatc ccgtactggg actggaccac cgacaccagc ccggtctcct ccctgtgggc
     5701 cgaggacttc ctcggcggca ccggccgctc ctccgaccgc caggtgatga ccggcccgtt
     5761 cgcctacgcg aggggcgact ggaccatcac cgtggggatc acggaggccc ggtacctgac
     5821 ccgcaacctg ggccgcccgc agaacccggt caccctgccc accccggccg aactccagtg
     5881 ggcgatcgac gacccgacgt acgacgcctc tccctgggac tccacggcgg gcggcttccg
     5941 caacaggctg gagggctggg ccgcgccgaa gagcgagcgc tggcgcaacc acaacaaggt
     6001 ccaccagtgg atcggcggcc acatgacggg cggtacggcg cccaacgacc cggtgttctg
     6061 gctgcaccac gccttcgtgg acctgctctg ggaccgctgg cagcagcggc acccctcctc
     6121 cgggtaccgg cccgccaccg cgccgctgcc gggcgacgcc cagcggggcc gggtgatcgc
     6181 gctggacgag ccgatgccgc cgtggaacat cagcccgcgg gagatgctcg gccaccaggg
     6241 cgtctaccgc tacgaggtct gaacgcaccc ggtcggcgca agggcccccg ccgaccggcg
     6301 ggggccctca gtgtcgttcc ggcgggcagg cgatcagccg ccgtagccct cggtgtgctg
     6361 ctgctgggtg gtggccgtgc cgccgcccga ggcgttgacg caggtgttgc cgaacgccgg
     6421 gttcagcagg ccgacgatgt tgacgctgtt gccgcagacg ttgaccggga cgtgcaccgg
     6481 aacctggacg aggttgcccg agaggacacc gggggagccg atcgccgcac cctgcgctcc
     6541 ggcatcggcg acagccagac cggcaccggc ggccacggcg ctaccggcga cagcggtgat
     6601 ggcgaatgcc ttcgcgatac gcgacatcaa gatctcctcg tgagatgtgg ggttgccaca
     6661 gaagctgcgg catttgacat ggcatacaac gcggggacgg cccaggggtc acgggcgctg
     6721 ctcctacccg gtgaccgaga accgcaccga ggcgaagtac ggccgcacct gggtgaccgt
     6781 ccccggcccg agccgctcca cgggggcgcc cgcgcagccc ggctcccggt agaacgtcgc
     6841 ggtgccccgg gtgtggttgg tgaccggccg ggaaccgccg ccctccgccg cgacacagcc
     6901 cttcggggcg gtgagcccgt ggacccggtc gtcctggccc acgtactgga agtccggacc
     6961 ggcggcccct gcgggcgccg tgccgcccgc ggccggggcc gccgtagccg tagccgtgac
     7021 cgccgcgacc gcggcggcgg ccagcagcag ggcgggaacc gcgccggtgc gcaggaggat
     7081 ccgcgtgtct cgcatgattc gcatggcccg tccaaccgga cccgccccgg gccgggtcac
     7141 gccggatcac ccgttggacg actgtgcgac cgtgtgcgac cgtgcctgga caggaggaac
     7201 ggctccagga ggacgggatg agagcaccga gcggccggcc ccgggccggc accgggtacg
     7261 gagtggtcga aggccggcgc gaggccggcg gcatcgccgt cttccgcggc atcccgtacg
     7321 ccgcaccgcc cgtcggcgcc ctccggttcg ccgcgcccgc gcccccggag ccctgggagg
     7381 gcgtccgcga cgccggcgcc ttcgggccca ccgcgcccaa ggtgccctac cccgacacct
     7441 tcgcggccct gctgcccgac ccggagatcc ccggggacga ctgcctgaac ctgaacgtct
     7501 ggacccccga cccggacccc ggcgcccggc tgcccgtcat ggtgtggatc cacggcgggg
     7561 cgctcacccg gggctccgcc gccgtccccg tctacgacgg cgccgccttc gcccgcgacg
     7621 gggtcgtcct cgtctccttc aactaccgcc tcggcgcgct cggttacgga ctcttccccg
     7681 acgccccggc caaccgcggc ctgctcgacc agatcgccgc cctcacctgg gtccgcgaca
     7741 acatcgaggc cttcggcggc gaccccggcc gcgtcaccgt cttcggggag tccgccgggg
     7801 ccatcagcat cggcgccctc ctcgccgccc cgcgcgccgc cgggctcttc acccgggccg
     7861 tcctgcagag cggcgccccc gaggtgctgc cgcgcgatcg ggtgcgcacc atggtccggc
     7921 ggatggccgc gctgctcaag gtgcccgcca ccgccggggc cttcacggcc gtcgccctgc
     7981 cggatctgct ccgcgcccag gcagcggtgc tgcgccgcac caactcgctc gtcggcggcc
     8041 ccgccttcgg cctggtggcg gaccccgcca ccctgccgga cgatccgctg gaggcggccg
     8101 ccgccgggga ggtgccgctg ctgctgggct ggaccgccga ggagtaccgg ctctggctgg
     8161 ccccgaccgg ggcgatgcgg gtgctggacc ggctcgggcc gctggccgtg tcgctggccc
     8221 gggcccgcag cggcaaggac cgggccaccg tacggacgct gcgcaccgcg ctgcccgggg
     8281 cgagcgccgc cgagctcgcg ggccagctgc tcaccgaccg gctgctgcgc gacccgctgc
     8341 ggcggctggc cggggcccgg cggtcggcgc cgagtcacct ctacgagttc cgctggcgct
     8401 ccggcgtccc cggcctcggc tcctgccacg ccctggagct gggcttcgtc ttcgacacgc
     8461 tccacgtacc ggaggccgcc tggctggccg ggcgggacac cccgcaggaa ctggccgacg
     8521 agatgcacgc ggcctgggtg cggttcgcgg tcacggggga cccgggctgg gccccctggg
     8581 acggcagcgg cccgccgaag gtgttcggcg ggccggagcg cgagggggag ggggccgggg
     8641 aggcgctggc ggctactcca ccggtccttc catgaccttg ctgatgaact cgatcgggcc
     8701 ctcgcccatg ttcgggacgt aggtcttggc gttgtgcttg ccgcccggga tgaccttcag
     8761 gctggtgtgg accgggccct tgttgccgta ggtggcgatg aacttctgca cgtccggcag
     8821 ggtcctcttg ttggactcgc tgtcgccgac ctggaacgcg atgtagacgt ccgggccctt
     8881 cttgtcgatc aggtccttcg ccagcagctc ggggttgttc tcggccttct ccttgtcgtg
     8941 gcccttccac agggaggagt ccgggacgat gtccgggccg gaggcgacca cggccttgaa
     9001 gcggtccggg tacttcagca cggccttcat gcccgcgaaa ccgccggtgg aggagcccat
     9061 gaaggcccag ccgtcacggg acttgatcgt gcggaagttc gccttcatca ggtccgggac
     9121 gtcatcggtg agccaggtgc ccatcttggg ctggccgggg atgtcggagc cgtcccagta
     9181 gacgcccttg tcgtccggac ccgggttgag cacgggcatc gccaggatga agggcttgct
     9241 cttcccctcg gcgtaccact tggagatgct ggactggagg ccgaggtcgg tgcccatcca
     9301 gtagttgttc gggtagccgg cgccgccggg cagagcgatc aggaccggga agccgctctt
     9361 ggcgaacttc gggtcgttgt actccttggg cgcccagacc cagaccttgc ccttgaagcc
     9421 ggacttcttg ccgtcgagcg tggtgacggc gatgtgcgtg ccgtccggca gcgtctgcgc
     9481 gttcttgaag tcggcggccg ggccggtcgg catcagcatc ttcgagttcg gcgcctgctt
     9541 ggcggcgccc ccgccgcccc cgcccccggc ggccggttgt ccgaaggaca cggcactgcc
     9601 cttgtccgtg aacgggggta tctcgaagtg gtacatcacg ccggcggcta tgccggcgag
     9661 gcccagcacg gccacgcccg cgatcagcca gcgcttgccg cgtgagcgcc ggcgcggctc
     9721 ctcggggggc tgcggcgggc cgtagtcgta ctcgtggccg tagccctggt ccgggcccgg
     9781 tccctggccg tagccctggc cctcctggcc gtagccctgg ccctgcgcct gcccgtagcc
     9841 ctggccctgg ccgtaaccct ggccctggcc gtacggcggg cctggcggcg ggccgtcgtg
     9901 cggtggccgg ggctgccggt actgcccttc cggtgccggc cggtaaggct ggtactgctg
     9961 ctgaccgtcg ggtgcgtagg acatcgcggt ggctctccgg cttgtgctgc ccgatcgggc
    10021 ggggggttgg ctgcttcctc tcggatgatg atcgcaaata cgttctggtt ccttattttt
    10081 ctttctcttg gggttccgta gggcaatgcg ttgcccatcg ctcagcggct cggtggagtt
    10141 cccgcgctgt tcgccgagta tccctggccc atgcacatgc cgctgggtat ggtgcgtccg
    10201 cgccgccgcc cccacccccc cctgcccgga ggtattcccc gtgtttggca tgtcccgttc
    10261 acaggtgagc cgtaagaccg ccctcgccgc cgccttcggc gtcaccgccg ccggcgcggc
    10321 cctgtgggcc ggcatcggag ccgcccagcc cgcgcacgcc gccggcctgc ccgcgcccga
    10381 ccacgtcgtc gtcgtggtct tcgagaacca cgcctacaac caggtgatcg gcagctccag
    10441 cgccccctac ctcaactccc tcaagacggg gggagccaac ctcaccaact ccttcggcat
    10501 cacccacccc agccagccga actacctcca gctgttctcc ggctcccacc agggcgtgac
    10561 cggggacagc tgctacaccc ccggcttcag ctccgccccc aacctggcct ccgagctgat
    10621 agccgccggc aagacctggg ccagctacaa cgagaccctg cccagccagg gctccaccac
    10681 ctgcagcagc ggtaactacg cccgcaaaca caacccctgg ttcgcgttct ccaacgtgcc
    10741 caccagcacc gccaagacga tgacccagtt cccggcggac ttcaccaccc tgcccaaggt
    10801 ctccttcgtc gtccccaacc tctgcaacga catgcacgac tgctccgtcg gcaccggtga
    10861 cacctggctc aagaacaacc tcaaggccta cgccgactgg gccaagaccc acaacagcct
    10921 cctcgtcgtc accttcgacg aggacaaccg gctcgcgggc aacaagatcc cgaccgtcct
    10981 ctacggccag cccgtcaccc ccggcagcac gtcgagcacc acctacaacc actacgacgt
    11041 gctccgcacc ctggaaggcc tcgccggcct gaccacccac gccggcaacg ccgccggcgc
    11101 caaggacatc acggggatct gggcctcctg accatgtacg ttgcggacag tcgcggcacc
    11161 cccgcgcccg ccgtgacccc cgagtcaccg gccgtcgccc cgggcaccag cccggggcgg
    11221 cgcgccgcgc tcgcccccac ggtgctcgcc ctcggcacgg tcagcctgat caccgacgtc
    11281 tcctccgaga tggtcacggc cgtgctcccg ctctacctcg tcgccggcct cgggctctcc
    11341 ccgctcggct tcggactcct cgacggcctc tacaacggcg tcagcgccct ggtccggctg
    11401 accggcggcc acctcggcga ccgcctcggc cgccacaagg ccctcgccgg catcggctac
    11461 ggcctctccg ccctgtgcaa accgctcctc ctgctcgtgc acaccctgcc cgccatcggc
    11521 gccgtgctcg ccctcgaccg gaccggcaag ggcctgcgca ccgccccgcg cgacgccctg
    11581 atctcgctgt ccgccgcgcc cgcggaccgc ggccgggcct tcggcgtgca ccgggccatg
    11641 gacaccgcgg gcgcgctgat cgggccgatc ctggccttcc tgatcctgcg cggcgccgcc
    11701 gacggctacg acgccgtctt caccgtcagc gcctgcgtgg ccgccctggg ggtcctggtg
    11761 ctggtcctct tcgtccccgg ccgccgcacc acggccgccc ccggcgccga gcccgtctca
    11821 ctgcgggcct ccgtcggcct gctgcgccgc cgcgacctgc gccggatcag cctctgcgcg
    11881 ctgctgctcg gcctgtgcac cgtcagcgac ggcttcgtct tcctgctcct ccagcgcgcc
    11941 accgggatcg ccgaccgctg gttcgcgctg ctgccgctgg gcaccgccgc cgcgttcttc
    12001 ctgctggcgc tgccgctggg ccggctcgcc gaccggatcg gccgccgccg ggtcttcctc
    12061 ggcggccacc tcgcgctgct cctcctctac gggctcctcc tcgtcggcgg gcagcacccg
    12121 gcgctgccct acgcggtgct cctgctgcac ggcggcttct acgccgccac cgacggcgtg
    12181 ctcatggccg ccgccgccgg gaccgtcccc gaggaacacc gcggcgccgg actcgccctc
    12241 gtccagaccg gccaggccct cgcgcggttc gccgcctcgc tgggcttcgg cgccgtctgg
    12301 accgtgtggg gcccccgccc cgcgctcgcc gtcgccgccg cgctgctcgc cgtcgcggcc
    12361 gccctctgcg tccggctccg gcccggcgcc gacgcctgac ccccaccccc gaaaggcccc
    12421 catgaccctc cagcgccgga tcctgatcct cgtctgcgcc gccgccctgc tcgccgccgt
    12481 gggcgcgctc gccgtcgtac gggcctcctc gcgcgccgac gagaagaacc aggcccgggc
    12541 cggcgggccc cggatcaccc ggggcgaggt ctccctgacc cccggcgacg gcggccggcg
    12601 gatcgtgttc cggaacatgg cctggggccc gcaccgcgac gagctcgcca ccgtcccggc
    12661 cggtgaaccc gaggggcccc gtaccgcctc cggagtgacc tgcctgcgct tccactccgc
    12721 cgcgggcacc ggcgtctgcc tccaggccga caagggcggg gtccaggaga gctaccgggc
    12781 ggtcgtcctc gacgcccgcc tcaaggaggt ctccgcgcac ccgctggcgg gcatccccac
    12841 ccgcgcccgg gtctcgcccg gcgggcacct cgccgcctgg accgtcttcg tcggcgggga
    12901 ctcgtacgcc ggaacgaact tctcgacccg cacctcggtg ctcgacctgc gcaccggtcg
    12961 gtacgacgcc tcgctggagg acttcaccat ccgcaaggac ggcaagacgt accgcaacgc
    13021 cgacgtcaac ttctggggcg tgaccttcac cgccgacgaa cggggcttct acgcgacgct
    13081 cgcgaccggc ggcaagacct acctggtccg cggcgacctg gccgggcgga ccgtgaccac
    13141 cctgcgcgag aacctggaat gcccctcgct ctcccccgac ggcacccggc tggtcttcaa
    13201 gaagcgggtg gagggcgccc cggcggaggc gccctggcgg ctgtacgcgc tggacctggc
    13261 cacgatgcgg gagaccccgc tcgccgagga acgcagcgtg gacgaccagg tggtgtggac
    13321 ggacgacaag accgtcgtct actccctgcc cggcgacttc ggcgccgacc tgtacgcggt
    13381 accggccgac gggagcggcg ccccggcccg gctgatggac tcggcgctcg ccccggcctt
    13441 cctcggctga gggccgggag gaccggggcg ggcgccggcc ggcaggaccg ctacgccggg
    13501 atcagcgtct tgcggcggcg cttgcgctgc gccgccgaag acagcctgag ctcgatgatc
    13561 gaccggaccg tcggccactc ctcgtcgagg atcgagtaga aggccgtact gcgcaccgcg
    13621 ccgtcgagcc cccgcgaatg ggcccggcgg accccttcac aggtgaaccc gaggcgctcc
    13681 atcgctgcgc gcgagcgccc gttacgggcg tccgcgcgca gcgagatgcg ccggacgccc
    13741 caggtttcga aggcatggcg gagcatgagc agcttcgcct cggtgttgat gccggttccc
    13801 tgggccgccg gggacagcca ggtattgccg atctcggcgg catcggggat cgccgtggcg
    13861 ggatcgccga acgggactcc cggcacggcg ggccacacga gcggcccctg ccagtagtcc
    13921 agttccagga accgggtcga accgacgacc cgcccgtcgg tggctctgac caccgcgaac
    13981 gggagcgatc gacccgctgc ctgatcggcg agggcacggt cgatgtactc gtgggacgcc
    14041 tgcaccccat ggggtacggg agtgaaggcg taagtcgtac gatcctcggc cccggccatg
    14101 gccaaggcct cggtgtggtg gggggcgagg ggctcgagcc gcacggagcg gccggcgagg
    14161 agtacgggta cgggcacgga gccttcggtc cttctgggcg gtggggtggt tgcacagtct
    14221 gcgctcctga cgtcgccccc cgtgcaaaac acgggtgaaa ggcaacgggc tgtcaggtga
    14281 acgcgagtgg ctcaatgtag cccctcaacg ggctctcatg aaccccctaa atggcaacgt
    14341 catggcgatg attttcgagg actttcgtcc ccgccgggaa gagccctcaa tcctgatccg
    14401 gggacatccc ttcaaccggt cgacgtggac ccgccaagcg gctgccccga gtggcgaaag
    14461 tcaccggttc ggcgtgcctg acctgcgacg atacggaggc gacccggcgt cgccgtacca
    14521 gcgcccggcc acctggacgc cgggccggcc cggccgggaa ccgggccggg cggccatcga
    14581 acaggcggcc gtcgcaggag tgtccagggg gcggcgggcc gaccgggtca cggcgttgcg
    14641 ccacccgggt ccgccgaggg tccgggcggg ccgccgcgga gcgttccgga gcgccccggg
    14701 gggcccggtt ccgagggggc gggcacccgc ccggcgcgcc cttgagatca tcgcgttcat
    14761 ggacatggac gacgtactgc ggcggctggc ctccgtcggg ccgttcttca ccgtgccgta
    14821 cgggaaggag ccccccggcc ccggcttccg cccgctcggc gacctctacg gggagcggct
    14881 gggcccgtac gtcaccgagg tgggccggcg gatccgcagc ggacccggcc gggtcgccgc
    14941 gtccaccgca cagctcggca tcgcctcgcg gctgtggtcg ctggggctcg gctgcgccgc
    15001 cctgggcggg cgggtgccgg atctgggcgt cgaccgggtg tggtggcggc tgcccgcggc
    15061 gggatcgctg gaactgtggc tgcccgagcc ggaaacgggc gcgctggacg ccggggcgct
    15121 gggggagaac gtgctgggca acctgggggt gctggacgcg gggctgcgcg agcggttcgg
    15181 ggtctcggcg aaggcgctgc gcggcaacac cgcctcaggg ctggtggggg cgctgcgggt
    15241 gctgctcgac cgggttccgg gcgggcccgc cgtctcgctc gcggcggacc tgctggccga
    15301 cggcggcgcc ctgggcggcg cgggcacctt cctgtacgaa gagggcctcg gggtggcctt
    15361 cgtacggcgc agctgctgcc tgtactacca ggtgcccggc ggggggctgt gcggggactg
    15421 cgtgctgcgg accaggtgag cgggcggtcc gtgcgaaccg gcgcgggcca ccggggcgcg
    15481 gttgcaccgc tccccgatgg ccctgcggca gcgccgtgac gtcgtcttcg accgccggct
    15541 cgccgacgcg tcccgcggcg ctagatccgc tcgtggcgac ccactagaac gtgaggttcc
    15601 aggcgtcgat cttgccggtg tcgccgccgg cgttgtcgtt cacgcgcagc ttccacgtgc
    15661 cgttcgcgac ctccgaggag gcgttgacgg tgtaggtctg cgcgatgttg tcggtgccgc
    15721 cgccggcccg gttgtggacc gtgtagacgg tgccgtccgg cgccaccagg tcgaccttca
    15781 ggtcaccgat gtaggtgtgc ttgatgtcca cgcccacctt gagggtggcc ggggcgttgc
    15841 cgctcacccc gctgaccgtg atcgggctct cgacggtggt gttgtcgccg atggcgacgt
    15901 caccgaggtt ctcgaagtac ttcccggacg gcggggtgct cccgacggcc ttgagggcgt
    15961 cgacctggcc ctcgccgaag aaggagttgt tggccgcggt gccggtgcag cggctgtccg
    16021 acgggcaggc gatgtcgttg gcctgggtgg ccagcttgtc gcggatctgc gccggggtga
    16081 tgccggggtt ggcactggcg atcagcgccg cgacgcccac gacgtgcggg gtggccatcg
    16141 aggtgccgct cttggtgccg tacttgccgc ccggcagggt ggagtagacg tcgctgcccg
    16201 gggccgcgac gtcgatgacg cccgagccga agttcgagaa cgaggccttc gtggtgcccg
    16261 atccgttcgc cgcgacggtg accacgcccg ggagctcggt cgggatgtcg aggcaggcgt
    16321 tggtgatggt gcgggtgacc ggggtcgagt cgttggggct cgcggtgtcg gtcgtcttgt
    16381 gggccaggtc gtagttctcg ttgccggccg cggcgatctg gagcgagccc ttgctctccg
    16441 cgtactcctg ggcgcgcttg acgccctcga tgatcgcggc ctggtcgatg ttgtcggggc
    16501 agttgaactg ccacgggtcc gtgtagtagc tgttgttggt gaccttgaag ccgtggtcac
    16561 cggcccacac gaagccgcag atggtgttct cggcgaagaa gaacgagttg cccggctcgg
    16621 cgacgcggac cgcggagatc ttcacgcccg gggccacgcc gacgacgccc ttgccgttct
    16681 tggcggccgc gatggtgccc gcgacgtggg tgccgtgggt gtccacgtca cgccaggcgc
    16741 cggtgcgggc gtccgccttg ccgtaggcgc aggagacgga gtcggccgcg ttgaagttcg
    16801 gcgcgaggtc ctggtgctgg tcgtccacgc cggtgtccag gacgccgacc ttgacggagg
    16861 cggaaccggt ggtgacggcc caggcctggt cggccttgat ctggctcatg tccgcgcgga
    16921 ccggctcgcc cgcaggggtg ctggactggg ccgggttggc gggcagggcc gggttgtagg
    16981 cgtccgcggg gacgtccgag gtgcgggtgg cgccgacctt ctggaccccg gagaccccgc
    17041 gcatggtggt ggcgaaggtg gaggaggccg agtgggcgac gatcacgccg atggcgtcgt
    17101 agttcgagaa caccgtgccg ccgttggcgg cgatggccga acggacggcc gagctgtcac
    17161 cgggggcggt gatcacgagg taggcgcgcg tgccggcaac ccaggtcgca ctctgggaag
    17221 acggcgcggc ggccttggcg ccacccgggg ccttggcgac cggggcgggg gccccggacg
    17281 gggagacggg ggcggtgccg gcgagcgcgg cgggggcccc gaaggcgagt gcggcgccga
    17341 gcgtggcggc cagcacgagg gtacgtcgag gtcggctgga tatgtggggt atcaatgcgt
    17401 cctccgaaga cggcccggag ctgctggtgg cagctaccgg gccgtacgaa acgagtggtg
    17461 gacgcaagat gtcagacggg tgccccgctg cggaagtacc ttttaccgca cgcgtattcg
    17521 cccgccgatg gctgaaaatc gaccatggat ggatgcgggg cggccgggtc cgctaggccg
    17581 ggacgccgtc cttgggggtg gccggctggg ccggtaccgg ggtcgcggcc ccgtcgtccg
    17641 cctggtcacc gtgcgtgtcc tccacgagcg tggtctcgtc gaacgggcag cggcccgcga
    17701 ggacttcggc ggcccggtcg cggtcgaact ccttcgtcca cgtcccgatc agcaccgtcg
    17761 cgaccgcgtt cccggcgaag ttcgtcagcg cccgcgcctc gctcatgaac cggtcgatgc
    17821 ccacgatcag gccgactccg tccacgagtt ccggccggtg tgactggagt ccgccggcca
    17881 gggtggccag gcccgcgccg gtgacgccgg ccgcgccctt cgaggccacg atcatgaaca
    17941 gcagcaggga gatctgctcg ccgatggcca gcggcttgtc catggcctcc gcgatgaaca
    18001 gtgaggacat cgtcaggtag atcgcggtcc cgtccaggtt gaacgagtag cccgtcggca
    18061 ccgtgatgcc gaccaccggc ttggagaccc cgaggtgctc catcttcgcg atcagccgcg
    18121 gcagcgccga ctccgaggag gaggtggaca ggatcagcag gaactcccgg cccaggtagc
    18181 gcagcagcgc gaacacgctg actcccgtgc acacccgcag cagcgtgccc agcaccacga
    18241 tcacgaacag cagacaggtc gtgtagaagc cgatcatgat cacggccagt gacttcaggg
    18301 cgtcgatgcc ggtcgcgccg accaccgccg cgatcgcccc gaacgcgccc accggggccg
    18361 cccacatgat catcgcgagg acccggaaca ccagcttctg tacgtgcccg atcccgcgca
    18421 gcagcggctc gcccgccggg cccatggcct ggagcgcgaa cccgcacagc agcgccacca
    18481 gcagcgtctg gagcacctgg cccccggtga aggcggagac catcgtcgtc gggatgatcg
    18541 ccagcaggaa ctccggcgtg ctctgcgccc cgcccgcctt ggcctgcgcc tcgccggcgt
    18601 gccgcgccgc ctcggtgagg tgcagcccgc tgcccggctc cagcaggttc ccgaccagga
    18661 gcccgatcgc cagggcgacc gtggacatga tcatgaagta gccgagggcg agcccgccca
    18721 cggcgccgac cttggcggcc ttgcgcaccg atccgatgcc gagcacgatc gtgcagaaga
    18781 tcacgggcga gatcatcatc ttgatgaggt tcacgaagcc ggtgcccagc ggcttcagtt
    18841 cgacggccac gccgggggcg gcgaagccga cggcgattcc gaggagtacc gcgccgatca
    18901 ccgcgatgta gagataatgg gtcttgtcgc gtctggcggc cacgctgcct cctggtggtg
    18961 aatgcgttcc gggagaccat cgcccgccga tgtgaccccg gtcacccttg cgttcattga
    19021 gttcatggcc gggtacacac tgagccccat gttccgtttg cctcggccgc cgcgctccct
    19081 cgccggccag ttgttcgcca tgcaggtgct ggtggtcgcg gtcatcgtcg ctggctgcgc
    19141 cgtgttcgcg tacgcgaccg cccgcggcca ggccgaggac gccgcccggc gccaggccgg
    19201 ggcggtggcc cgctcggtcg ccgactcccc gtccgtccgc gaggcggtgc gcgaggcggc
    19261 gccgggcacc gcccccgcgg ccggcctccc gacaggctcg gcgacgggcg ccccggcgag
    19321 ttccgcgacc cgctccgcga ccagccctgc gaccggctcc gcgaccggtc ccgcgaccgg
    19381 tcctgcgacc cgctccgcga ccggtcccgc gaccggctcc gcggtcgatg ccttcgccgc
    19441 gctctcggcc gagctccagc cctacgccga gcgggtgcgc accgactccg gagtggactt
    19501 cgtgacgatc atggccccgg acgggcggcg ctggacccac cccgacccgc gccgcatcgg
    19561 ggagcggttc atcggcaaca ccgcccccgc cctgcgcggc gagaccttca gcgagaccta
    19621 caccggaacc ctcggcccct cgatccgcgt ggtcaccccg ctgagcgaca acggccgggt
    19681 gatcggcatg gtcagcgccg ggatcaccgt ccgcgtcatc ggcgaccggc tggccgcgca
    19741 gctcgtcgtc ctcggctggt tcgcggccgg cgccctcgcc ctgggcggcg cgggcaccta
    19801 cgtggtcaac gcccggctgc ggcggcacac ccacggcatg aacgccgccg agctgagccg
    19861 gatgtacgac taccaccagg cggccctgca cggcgtccgc gagggactgc tcatgctcga
    19921 cggccagcgc cggatcaccc tcatcaacga cgcgggccgc gaactcctcg gcctggaggg
    19981 gaagatcagg ggaaccggcg tcgccgacct cgggctgccc gcaccgctga ccggcgcgct
    20041 gctcgccgac gggccccggg tggacgaggt gcacctgacg gccgaccggg tgctggtcgt
    20101 caacagttcg cccgtcgccg gcggcggccg caagggcacc gtagtgaccc tgcgcgacca
    20161 caccgaactc cagtcgctga ccggggaact ggaccacgag cgcgggttca cgcaggccct
    20221 gcgctcccag gcccacgagg ccgccaaccg gctgcacacc gtggtctccc tcatcgaact
    20281 cgaccgggcc gaggaggcgg tggagttcgc caccgccgaa ctggagctgg cccaggccct
    20341 caccgacgag gtggtcaccg ccgtcgggga accggtgctg gtggcgctgc tgctggggaa
    20401 ggccgcccag gcgcacgagc gcggcgtgga gctggtcgtc accccggaca gcagcgtgat
    20461 agacgggcgg accgggatcc cgccggcccg cgacctcgtc acggtgctcg gcaacctcgt
    20521 ggacaacgcg gtggacgccc tcagcggggt ccccggcggc cgggtcatgg tgacggtgcg
    20581 cgccgagggc gacgggctgc tcatccgggt cgccgacaac gggccggggc tgcccgaggg
    20641 cgcggacgtg ttccggcgcg gctggtcggg caagggcgag gggcgcggcc tcggcctcgc
    20701 gctggtgcgc caggtggccc accggcacgg cggcagcgcc gatgccggcg cgcgtgccga
    20761 gggcggcgcg gagttcaccg tacgactgcc gacgcgcggg gaggcggggg catgagcgcg
    20821 cccgaggtgc gggtcctgat cgtcgaggac gaccccgtcg ccgccgccgc gcacgcgctc
    20881 tacgtcggcc gggtgcccgg gttcaccgcc gtcggcgccg tgcactcgct ggccgaggcc
    20941 acccgggtgc tggagcggac cggggtcgat ctgctgctcc tggacctgac cctgcccgac
    21001 gggcacgggc tgcgcttcgc ccgggggctg cgggccgccg ggcatcccgt cgacgtgatc
    21061 gtggtgacct cggcgcgcga cctcgcggtg gtccgggaga gcgtctcggt cggcgtcgtg
    21121 cagtacgtgc tcaagccgtt cgccttcccc accctgcgcg aacggctgct gcggtacgcg
    21181 gagttccgcg cgacggcggg tgaggcggcg ggccaggacg acgtggaccg ggccctcgcg
    21241 gccctgcgcg cgccccgccc ggccgagctc ccgaaaggcc tcagcgcgcc gaccctggac
    21301 agggtcgccg cgctgctgcg ggccgcgccc gaagggctga ccgcggccgg ggcggccgag
    21361 gctgcgggga tctcccggat caccgcccgg cgctatctgg agcacctggt ggacaccggc
    21421 cgcgccgacc gcaccccccg gtacggtcag gtgggccgcc ccgaacttca ctaccgctgg
    21481 ctggccgccg ccggctcggt gtcgaaggtg tagaacttgc ggtggtccag catgtcggcc
    21541 ggggtcacgt tgttccacgg ccgcatggtg tcgtgcaggt ccaccacgtt cgaggtgccc
    21601 gccgccggca ggtacgtcga acgcgggttg cgggcctgcc agtcggccca cagcttgtcg
    21661 acgaaggcgt ggtgcatcca gaacaccggg tcgttggggg agaccccggt ggccatctgg
    21721 ccgccgaccc acacgtgcac ccggttgtgg aggttggcgc cgcgccagcc ctccaggttg
    21781 ttgcggaagc cgttcgagga gctgttccac ggggccatgt cgtagaccgg catggacagt
    21841 acggcgtcca cctcggcctt cgtcggcagc tcggcgacgc ccgcgccgag ggcgcgccgc
    21901 aggtagttgc ggccgtccac gcggacgttg atgtcccact tgcccgtcgc gtacgcgaac
    21961 ggtccgtcgg tcacctggcc gtcgcgcgcc cggccggtgc cgccgaggaa gtcggcggcc
    22021 cagagggagg atctggtggt gcggtccgcg ctccagtccc agtaggggat ggtgaccttg
    22081 gcgtccaccg tctgcagcgc ggcctcgaac tccaggagga agcggcggtg ccagggcagg
    22141 aaggacggcg agcggtggcc gacgcggtca cccgagtcgg tgtcgctcat gatgaagccg
    22201 ttgtgcgtgg tgacgaagcg gtcgtaggcg ccggtgcgct tgagctcgat cagcgcgttg
    22261 gtgaaggcgc gcttctcctc ggcggacagc gtggcctggt tcttgcgcac ggtcatgccg
    22321 cgcctcccat cggtgcgaac ggagcgagct gggcgccctg gagctcgcgg accgcggcgc
    22381 gggcgagcga ggtggggtcg gcgaaggtct cgtagtggtt gaccacgctg atccaggtgc
    22441 cgtcggcgtt gcgcatcacg tgcagttcgc ggccgtctat tcggaccgtg ggcagatcgg
    22501 agccgtggtg gccgccgtgg tggccgccgc ccgtggcggg gctgatctgg atgcggcgtc
    22561 cctggaacac ctcgtcgacg gttccggcgg gggcggcggg ggccggggat gcggcggtcg
    22621 cgctgtgggc ggcggcgccg aggagaccga gggcactgag cgtgccggcg gtcgtgccca
    22681 gggcctgccg gcgggtgatc ttgttcatgg ccgaagaact atcagggcgg tgcggccggt
    22741 tgttcgatat caggacatcg ttcgacaagt tgcggatcga acgaattgac cgatcttccc
    22801 gtccgtaccg gctccagcgg ctcggacagg aagatctacg cgcgtaatcg tatcgaacga
    22861 taaaatctcc ggcgaacccc ggtggctatg tgcagcgtca cacgctggag tcgtccggat
    22921 acagaagccg gaattgtctg gttggttcac ttatagtccg gatatggctc tgcatgagac
    22981 gaaggacgta cccgcccagg acgccgacac ggacgtgttc acttccgcgt tgagtggcga
    23041 gatcctcccc aagtaccgga tgccggagga ccactcgccc tccgaggtgg tctacgagct
    23101 cctgcacaac gagctcctcc tcgacggcaa cgcggcccag aacctggcca ccttctgcac
    23161 cacctggtcc gacgacggcg tgcgccgcct gatggccgag tgcctcgaca agaacatgat
    23221 cgacaaggac gagtacccgc agacggccga gatcgaatcc cgctgcgtca acatcctggc
    23281 cgacctctgg aacgccccct ccggcggcgc ggccaccggc tgctccacca ccggctccag
    23341 cgaggcggcc atgctcggcg gcctcgccct caaatggcgc tggcgcgaac gccgccgcgc
    23401 cgcgggcctc cccgtcgacc gtcccaacct catctgcggc ccggtacaga tctgctggga
    23461 caagttcgcc cgctacttcg acgtcgagct gcgccagatc ccgctggagc ccggcgccac
    23521 cggcctgcgg ccccaccagc tcgcccagta cgtggacgag aacaccatcg gcgtcgtcgc
    23581 catcctcggc gtcacctaca gctgcgacta cgaacccgtc gccgagatct gcgccgaact
    23641 cgaccggatc caggccgaac acggctggga cgtacccgtc cacgtcgacg ccgccagcgg
    23701 cgggttcgtc gcccccttcc tgcaccccga cgtcgtctgg gacttccggc tgccgcgcgt
    23761 ggcctccgtc aacacctcgg gccacaagta cggcctggcc cccctcggcg tcggctggat
    23821 cgtctggcgc accgccgacc tcctccccgc cgacctcgtc ttcaacgtgg actacctcgg
    23881 cggcgacatg ccgaccttcg ccctcaactt ctcccgcccc ggcggcgagg tcatcgccca
    23941 gtactacctg ttcctgcgcc tgggccgcgg cggctaccgg cgcgtccagc tggcctgcgc
    24001 cgagaccgcc cagtacctgg cccaggagat cgccgcgatg ggccccttca ccctcctcta
    24061 cgacggccgg ggcggcctcc ccgccgtctc gtacaccctc gccgacccgg aggggagccc
    24121 cttcacgctc tacgacctct ccgaccggct gcggatgcgc ggctggcagg tgccctcgta
    24181 cgcgctgccg gccgaccgcg acgacaccgt catccaacgc gtcctgatcc ggcatggcgt
    24241 gacccgcgat cagatcgccc tgctcgcctc ggacctgcgc aaggccgtgg agcacctcac
    24301 cgccacaccg ccgcccgtgc ccgccaccga gccccggtcc ggcttccacc actgacggtc
    24361 aggcggacgc cgaccagcgc atgcccaggg ccgtcagcgc ctcgacccgc tccggggtga
    24421 gcgacgcggc gcgggaacgc tggttggcga tccacgaacc cagcttgaac tcccgcccgc
    24481 cgacccgctc cacatgcgta cggggcaccc gcaggtgccg ctcgcgctcg tggaagcgcc
    24541 gggccgcctc caggtgcgcc gcccaggccg ccgcgtgggc gacccgcggc ggggggagct
    24601 cggccccggt cgccggggcc gcccccagcg tgtgctccag cagccagcgc tgcgcccagg
    24661 acagccgctc ccaggacagc cgctgggacc gcagccacag gcccaggtcc tcgccctgca
    24721 ccagcacctc gcccggaccg gccgggagcc gcccgcccgc gtccaggtgc acccgggtca
    24781 ggtggaaggc ccgctgccag gagaccggcc aggccgggca ccaggccgcg tcgatctcct
    24841 ccagggcctc gcgccgctcc tgcgacagcg cgcccgcacc ctcgcggcgg gccgccgcgc
    24901 gctggttctt cacccagatc ccgaccggcg ccccgttcca ggtggcgtcc gccggcggca
    24961 gcaggtgccc gtgctccgcc gcccaggcgc gggccgcctg cagcccctcc tcgaacgcca
    25021 cgtcgaagtg gctccacacc atgcccagcc ggtccagctc cgccacccgc tcccggccca
    25081 gcgcgccccg gcggtacgtg cgccgcgcgt ccgcgatcca ctggccgagc gggaacccgg
    25141 ccagcccggg cggccacggc gacgcgcccg ccggcacccg gtgggcgaac ggcaccttca
    25201 ggtccccggc gccctccgcg tagatccggg ccgcctcgac cccgcgccgc cagtgctcgt
    25261 gctccgggtt cagcacccgg agccggacga acgccgccag cagcgccgga tcgcgcgggg
    25321 tggcgaagct cagcagggac tccgccgcgg accccgcccc cggcgctccc gccgggcggc
    25381 ccggggcctg cggctgggcg agggcctcga cgagccgggt gtcgtgcgcc cgcagcgcct
    25441 ccagcagccg cgcgaggctc ccgtacgccc gtgaggtcag catcgactcc ggtgtctcgc
    25501 ccggccccag gagcaccggc accaccagcg aggcgacctt tccctcgccg ggccggatcc
    25561 gcagcgcccg gccgaccgcc tggaccaggt cgggcatcga gccgcggacg tccgcccagt
    25621 acacggagtc gcactcggcg atgtcgacgc cctcgcccag cacccggacg ctgccgagga
    25681 aggccttctc ggcggcctgg cccgaggcga actccgccag cacccggcgg cggtgcgcgg
    25741 gcgggtgcag accgcacagc cagtcggccc agaccgtccg gggatacacg ggccccttgg
    25801 gctccccggc tcccgggcgc gctcctcccg cggacctccc cggggccccg ccgggaggcc
    25861 gggcggaccg caggcgccgc gccaccgccg ggagtccggc ggcgaacgcc tcggcctccc
    25921 gcgtcaggtg gtggaagacg agcgtccgcc ggaacccctg gtccgcggcc gccttcacca
    25981 gcgccgtctg caacgccgcg agccggctcc cgcgcaccgc gtccgagcgg ccgtccgggc
    26041 ccagcagcac ggccgcctgg aagcccggat cggtgacgtc cacacagacc acccggtacg
    26101 gggcgcagat cccccggtcg atggcctcgg acagggtcag ggtgtggcag cgcgccccga
    26161 acggtcctgc cgggtcgtcc tccatcgagg cgacgagccc gctccgaccc cggccgccgt
    26221 cgtccgcgcc gtcctcaccg ctctcgccgc cctcttcggg aggctcgccg tcctgccaca
    26281 cgcggggcgt ggccgtcatg tacagccgcc ggagggcggg gatccgggcg ttgtcgtgca
    26341 ccaccgccca gggcttgccg atccgcccgg acgtacggtg cgcctcgtcg accacgatca
    26401 ggtcccaggc cggcagcccc gcgaggtgcg cccgctcgat cgtgcccatg cccagcgagg
    26461 cgtacgtggc gaacaccgtc acccggtccg ccacccggcc gccccggcgg gccagttcgg
    26521 ccggatcggt ggtggtgggc atcccggcgt cgtcctcgcg cagcgagcag acggcgaggc
    26581 gccgcccggc ccggccgccc tcccgccagg ccgccgccgt ctgcacgagc aggtccaggg
    26641 tgggcaccag gaccagcacc cgggccgccc ggagctcctg cgccgagcgc acggcgacca
    26701 gcgacttccc ggaacccgtg gccatgatca cctgggtccg caggcccgcc tggggcaccc
    26761 ggcccccggc gggcagctcc agcgcccgcg ccacggcgtc gaccgcttcg cgctggtgcg
    26821 ggcggagctc tttcctcgcc ataccgcagt tctccgtccg cccgcgctct gaacagccct
    26881 ttcggctcca gtctccatcc tgccggaaac ctgaggcggc gggggcaggc gcgggcggcg
    26941 ccccggctac atcttggcgc cgaagttctg ggtccaccac gggccgccgg cgccctggtg
    27001 gatgcccacg ccgatctcct tgaacgcgca gttgaggatg ttggcgcggt ggcccgggct
    27061 cttcatccag gagtccatga ccgagtcggc gttctgctgc ccccgcgcga tgttctcccc
    27121 gtacgtcgac caccggtacc cggcggcggt cacccgcttg cccgggtcgg ccccgtcggg
    27181 gttggtgtgg tcgaagaagt tccgggcggc catgtcgtcg gagtgcccct gggcggccga
    27241 gcggagctgg gagttctccg tgagcggccc gcagcccgcg gcggcccgct ccttgttgac
    27301 cagggcgatg acctgacccg cgacccccgg cggggcgggc gccggcgccg gggccgaggg
    27361 cttgggcggc gtggacttgg tgcgggtcgg cgaggggctc gcgctcgcgg tggacgcgct
    27421 cggcgacggg gaggcggagg cggaggccga cgcggagggg gacggcgagg cggaagccga
    27481 agcggacgcc gagggcgagg gcgaacccga ggggagcacc gcgtcggggg ccgacagggc
    27541 cgccagcggc gaagcggtcg cgccgccctc ggcctcggtc ttgccggagc ccggcagcgt
    27601 accgaggtag accagcccgc cgcccgcgac gcacgcggcg agcacggccc cgccgatgac
    27661 ccggcgccgg ttctggcgcc gcttgcgcag gacgccgcgg ccgcccgc
//
