LOCUS       NZ_BMVE01000003        22637 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces goshikiensis strain JCM 4640 sequence03, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVE01000003
VERSION     NZ_BMVE01000003.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 698120)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650555.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:30:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,491
            CDSs (total)                      :: 7,410
            Genes (coding)                    :: 7,286
            CDSs (with protein)               :: 7,286
            Genes (RNA)                       :: 81
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 44 of 125
            Pseudo Genes (incomplete)         :: 101 of 125
            Pseudo Genes (internal stop)      :: 9 of 125
            Pseudo Genes (multiple problems)  :: 27 of 125
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 68502
            Orig. end                         :: 91139
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVE01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22637
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22637
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22637
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12637](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12637)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(301..316)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.55"
                     /tool="antismash"
     misc_feature    550..563
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.35"
                     /tool="antismash"
     gene            553..1911
                     /locus_tag="IE248_RS10390"
                     /old_locus_tag="GCM10010336_21110"
     CDS             553..1911
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743197.1"
                     /locus_tag="IE248_RS10390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21110"
                     /product="hypothetical protein"
                     /protein_id="WP_073798477.1"
                     /transl_table=11
                     /translation="MDTHEDLGTGSGHPWFGRHRLRPAAPADTIRRMLRHELRDTGWPY
                     QRVLPAAPMAIPRASYAEIFRVSVALIELLRRTALESGPTTADRLSAYDMPATEDRLWM
                     GDPFIEERYADSVVRPDLVIGPDGPRFLEFNVSGALGGVVETRSRLAVWRGLHADEDGR
                     TPFRSPDPFDVRADMFRSLGAELGLAPRVAVVGSARVIGVERRYFEMEADHYNSHGLTA
                     RFFEPEELPEAWDCAPHLRHQVGLRNFTIPDWLEVGIDTTPVQDALDNGCLLVGTQTST
                     FMHSKLTMGLLSEGRPWMTAADRGLVERYLPWTRILSERKTDREGQQVDLLPFVLGNRE
                     LLVLKAGLGESGKQVVIGREVDQAGWESAVGAAVAGGTSVVQAFVEPQTCRVSLIADGC
                     DEPYDADVAPVLGPLVFGGRPAGLFCRFFGDGSAGIVSVRGGTSSSDNVMVAI"
     gene            1971..2252
                     /locus_tag="IE248_RS10395"
                     /old_locus_tag="GCM10010336_21120"
     CDS             1971..2252
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743196.1"
                     /locus_tag="IE248_RS10395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21120"
                     /product="DUF3253 domain-containing protein"
                     /protein_id="WP_008743196.1"
                     /transl_table=11
                     /translation="MTHGDRETERRLERAILELLEGRGPTATICPSDAARAVYAGSDDG
                     WRVLMEPARRAARRLVGAGEVEITQAGRPVDPATARGPVRIRTARRRP"
     gene            complement(2270..2932)
                     /locus_tag="IE248_RS10400"
                     /old_locus_tag="GCM10010336_21130"
     CDS             complement(2270..2932)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523142.1"
                     /locus_tag="IE248_RS10400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21130"
                     /product="deoxynucleoside kinase"
                     /protein_id="WP_190030559.1"
                     /transl_table=11
                     /translation="MLVICVGGMIGIGKTSVAELIAKELGSEVFFESVEDNPILPLFYT
                     ASPEEIQAKRYPFLLQLYFLQTRFAAIKDAYHRADNVLDRSIYEDWYFAKVNHGLGRIS
                     SLEMQVYEGLLGEMMREIEGLPYRKAPDLMVYLKADFETVMYRIGLRGRDFEQDEALVE
                     YYRTLWSGYDDWVHKHYSASDVLVIDMNRTDVVNNPEDAARVAQEVKDALAAVAARR"
     gene            complement(3192..3743)
                     /locus_tag="IE248_RS10405"
                     /old_locus_tag="GCM10010336_21140"
     CDS             complement(3192..3743)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381703.1"
                     /locus_tag="IE248_RS10405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21140"
                     /product="YciI family protein"
                     /protein_id="WP_073798479.1"
                     /transl_table=11
                     /translation="MEFFCYHRDRPGSTALRMELLERHWSYMDQYEKELIARGPTFAPG
                     GDAPSGSVHIVDLPDPAAARAFAFDEPGYQAGVYRDVLLLRWRDMLGRTMWDFPGGRTG
                     GNRYLVLGLGAGGAADLTAAPGCRDDLIAYGPLLSDDATTWLGTAALVRAPDADAARGV
                     LAVERYADIEIHPWEFGGRR"
     misc_feature    complement(3727..3743)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.34"
                     /tool="antismash"
     gene            3855..4043
                     /locus_tag="IE248_RS10410"
                     /old_locus_tag="GCM10010336_21150"
     CDS             3855..4043
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321482.1"
                     /locus_tag="IE248_RS10410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21150"
                     /product="DUF6381 family protein"
                     /protein_id="WP_037794818.1"
                     /transl_table=11
                     /translation="MSVEDPSGKRAQEMRDKAQELEQAAQYAADPAERQRLTQKALHIR
                     EKSEQVYGFGAGTMDPM"
     gene            complement(4063..5007)
                     /locus_tag="IE248_RS10415"
                     /old_locus_tag="GCM10010336_21160"
     CDS             complement(4063..5007)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743192.1"
                     /locus_tag="IE248_RS10415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21160"
                     /product="5'-nucleotidase"
                     /protein_id="WP_073798480.1"
                     /transl_table=11
                     /translation="MRYDLSGRLVVGIASSALFDLTDCDAVFREQGEDAYRAYQEAHAD
                     HALAKGVAFPFVRRLLSLNDLSDRSDPLVEVIILSRNDPDTGLRVMRSITAHHLPISRA
                     VFRQGRPSHSFMRALNMSLFLSANGPDVRDAVAAGLPAGHVLHTARIDDESDPELRMAF
                     DFDGVLAGDASERVFQSLGLDEFRAHEVREAATPHDPGPLRPFLAGVNRIQRREEERRR
                     GDPAYQPRLRVSLVTARDAPTHERAIRSLKDWGLRVNDAFFLGGIEKAAVMRTLDPHIF
                     FDDQVSHLNGTAHGTPSVHVPFGVVNAQPPATT"
     gene            5370..5975
                     /locus_tag="IE248_RS10420"
                     /old_locus_tag="GCM10010336_21170"
     CDS             5370..5975
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="IE248_RS10420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21170"
                     /product="response regulator transcription factor"
                     /protein_id="WP_190030560.1"
                     /transl_table=11
                     /translation="MTKVLVLHSVCLVRSALAALLRTEGDFDVTSCGWRAAGRQAASLR
                     PDVAVVDLDCPGASAALLADADAARPLPRSTPLLVLARADTPGSLRRAFLTQAQGYVDK
                     DGSPARLVRAIGRVAAGERSIDATLASAFMEADPMPLSPRELSVLARAAEGDSIAEIAR
                     ALHLASGTVRNYMAAVTRKTGARNRIDAIRISRRAGWV"
     misc_feature    5499..5501
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6007..7749)
                     /locus_tag="IE248_RS10425"
                     /old_locus_tag="GCM10010336_21180"
     CDS             complement(6007..7749)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849358.1"
                     /locus_tag="IE248_RS10425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21180"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190030561.1"
                     /transl_table=11
                     /translation="MSGDGSWRRVSREGRRFLRGRYRSLRRLALWSLLESAHTFLGGYA
                     VARALDDGFLAGRTGTGLGWLAVAGAGALLGALALRGVFGGLADLVEPLRDGLVRRSVR
                     QAIGRAVADPGRAGDAGAVSRLTQQTEMARDSFAGLVLVARSFVFTALGALLGLAALDP
                     VLLVLVLPALLLGTAGFLATLRPMARVQRAALDADEALSGRAGELAAGLRDVVACGGGA
                     SAGAPVERLIAEQERLTGRLARWTALRTLALGVAGRLPVVALLAGTPWLLGRGVSAGAV
                     AGALTYLVQSLLPALDALMTAVGAAGTRLLVVLDRFCTPQSDSPAATTAPEAAPGVGAG
                     PGVAVELRGVWFAYGPRAQPVIDGLDLTVGAGEHLAVVGPSGIGKSTLTALIAGLLPPG
                     GGTVRVAGAPAQGVTGPGPDLRRTLLPQQAYVFTGTVRENLTHLCPGPVSGAEVERATA
                     ALGSDGLVDRLGGLDGAVDPARLSPGERQHLALTAAYLSPAPLLLLDEATCHLDLRTEE
                     RAERALAARPGTLVVVAHRISSAARADRVLVLDGTRAVCGTHAELPARSPLYRDLVGLW
                     NARG"
     gene            complement(7746..9800)
                     /locus_tag="IE248_RS10430"
                     /old_locus_tag="GCM10010336_21190"
     CDS             complement(7746..9800)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983509.1"
                     /locus_tag="IE248_RS10430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21190"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_229895237.1"
                     /transl_table=11
                     /translation="MTAPDPTREAEAARGADRALRAAARHSGGRLAAAAVCSVAAACAA
                     LAEPAVLGHTLDLLLRQDPGGARWTAWCAAVIAAEVLLDAVTARLTGGVDARSTAWLRR
                     LGLGRLLRAAPHHAARHSPGELSARLTAQATTAGAVPAAVVGAAVALLAPLGGLVALVL
                     VDVWTALAFLAGLPLLALLLRAFARDSGASVGRYQEVQLAMAGRLVEALAGARTIAAAG
                     TAEREQARVLSRLSELGAEGRETWRIYGTTMARTGALMPLLLYVVLGVGGVRLAEGALG
                     VGGLLAAVRYAGLAAGVGAVTGRLAAVVRGRAAARRTAALFELPELPQGVRRLPPGGPG
                     ALELRGVRVLRGGTAVLRDIDLRIPGGTTAAVVGRSGSGKTTLAAVAGRLTACNAGRVL
                     LDGVPLDELSAGELRREVGHAFERPALFGEDVAAAIAFGSGPAPTPENVRAAARAAGAD
                     AFVRRLPDGYDTALPDAPLSGGELQRLGLARAFCRAGRLLVLDDATSSLDTLTAREVER
                     ALTHDVRPGTRLVVAHRISSAARADLVVWLDAGRVRATGPHTELWRDPAYRAVFATGTD
                     PAAARAEGTGSEPDTKPAAASALAAAPAPPAAGRPGAQRNTGSDAATGAAPARAQGTGS
                     ELDTGPAAAAGPRTGAAPGEGPDAGASAGTGSAAAGGGGRRAPGRKTVR"
     gene            complement(9867..10004)
                     /locus_tag="IE248_RS10435"
                     /old_locus_tag="GCM10010336_21200"
     CDS             complement(9867..10004)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946992.1"
                     /locus_tag="IE248_RS10435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21200"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_030723876.1"
                     /transl_table=11
                     /translation="MTLLDLQSMETPKEETTEAAHGGGGGSRASLLLCGDSSLSITTCN
                     "
     CDS_motif       complement(9942..10004)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLLDLQSMETPKEETTEAAH"
                     /locus_tag="IE248_RS10435_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9867..9941)
                     /prepeptide="core"
                     /locus_tag="IE248_RS10435_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="20.90"
                     /molecular_weight="2100.3"
                     /monoisotopic_mass="2099.0"
                     /core_sequence="GGGGGSRASLLLCGDSSLSITTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLLDLQSMETPKEETTEAAH"
                     /leader_location="[9941:10004](-)"
                     /alternative_weights="2118.3"
                     /alternative_weights="2136.3"
                     /alternative_weights="2154.4"
                     /alternative_weights="2172.4"
                     /alternative_weights="2190.4"
     gene            complement(10001..12637)
                     /gene="lanKC"
                     /locus_tag="IE248_RS10440"
                     /old_locus_tag="GCM10010336_21210"
     CDS             complement(10001..12637)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072047.1"
                     /locus_tag="IE248_RS10440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21210"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_190030562.1"
                     /sec_met_domain="micKC (E-value: 6.3e-241, bitscore: 797.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.8e-12, bitscore: 42.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.9e-07, bitscore:
                     23.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGYAAFCDADRWFYDAPYRRAEENYPAALAPVPAGWQTHRSGD
                     WLALRPLDARLPSQGWKIHVSACLDNAESVLERVYRYCVERRIAFKFVPSRYLLHLRNA
                     KYADRAASGKFLTVYPADEEQCGRIAEELDALLAGEPGPYILSDLRWNGGPVHLRYGSF
                     TLRHCYDDRGELVPAIEAPDGRLVPDPRGPVFQTPEWVELPAFLAPHLAERAAVTLEGL
                     PYTVERALHFSNGGGVYAGRDVRTGEPVVLKEARPFAGLAADGADAVTRLDRERRALEQ
                     LAGLDCVPAVHGTFTVGDHHFLVMRYLEGKPLNTYFARRHPLIEADPDPAELAEYTRWA
                     LEIHRRVTEAVEAVHARGIVFNDLHLFNIMVAEDEETGEPSVSLLDFEAAAHVDEGLRQ
                     TVANPAFVAPADRRGVAVDRYALACLRLALFLPLTSLLVLDRGKAAHLADIAAEQFPVP
                     REFLDEAVREILAGAEGAPPAVVPRRPYLPVEPGDWEAARASMTAAIRASATFDRDDRL
                     FPGDTAQFANAGGGTGFGYGAAGVLYALAETGADPWPEAEEWLLARTKEPASGMPLGFY
                     DGLAGIAWTLERLGHRDRALALAEQLLGHPWQSAGPDLHGGLAGIGLALDSLGTATGES
                     ALHAAALRCADLLAESEAAAGSKRAGLLHGHSGPALLHLRLYERTGDRESLLRAGRALH
                     RDLDRCVTSVFGTLQVDEGWRTMPYLGAGSVGIGMVLDDWPAHTPDERFERARPEIVRA
                     AQATFYAQPSLFRGAAGMILHLARTTTPGPGSGPEDIARQVEALARHAVPYQGFLAFPG
                     EQMMRLSMDLSTGTAGALLALGSAAPGGRAQLPFLPPPRSAAAAPEPVPLVGAVSHRNT
                     TVKRNQT"
     misc_feature    complement(12029..12031)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12902..14263
                     /locus_tag="IE248_RS10445"
                     /old_locus_tag="GCM10010336_21220"
     CDS             12902..14263
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548912.1"
                     /locus_tag="IE248_RS10445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21220"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_190030563.1"
                     /transl_table=11
                     /translation="MGRRWAARLSLAAGVAALLVLVVFGGLVSLVLMGVGWAGLALSAA
                     GVWWMLTHTGRIRVLAVLLLVAVPLAVLALYAAAGLLWVVLVSLGLWALAVFAGRAALV
                     EDAPPAMPEHPARRPERPFLIMNPRSGGGKVTKFRLAERARALGAEVVVLDPDRPQDVA
                     QLAREAVRRGADLLGVAGGDGTQALVAGVAVAHDLPFVVISAGTRNHFALDLGLDRKNP
                     ARCLEALTDGVELRVDLGYLRAGGPEEPEEPAEPGTEVVFVNSASFGVYAEVVQSPAYR
                     DDKVRTILEMLPDLLAQESGARLSVRGDGPVLEAPQAVLVSNNPYQRGDSAGLGRRERL
                     DTGELGVLGVHVGSAAEAAELLLRGGQQGRGLTETTAREVVVDADAPVIPVGVDGEALT
                     LPTPVRCRLAPGALRVRVPRHRPGVRLGAPPMDWRRVRRLALTMGRAAAGRGPA"
     gene            complement(14289..15671)
                     /locus_tag="IE248_RS10450"
                     /old_locus_tag="GCM10010336_21230"
     CDS             complement(14289..15671)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018533976.1"
                     /locus_tag="IE248_RS10450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21230"
                     /product="MFS transporter"
                     /protein_id="WP_073798485.1"
                     /transl_table=11
                     /translation="MSDTRTPRRPSGAQRRVLAPLALAQFICSFAGSNMNVMINDISED
                     LDTTVQGVQTAITIFLLVMAALMIPGGKLTDRYGRKRCLLVGLVVYGIGALLSAAAPGL
                     GVLILGNSILEGIGTALLIPPVYILTTLIFTDLASRARAFGVIMALGGIGAAAGPLIGG
                     LITSALSWRAAFVFQALVIAVIILLSRRLEDPLPPDPTRSFDTTGAVLSAAGLILVVMG
                     ILAADDSLWLTLALLALGALVLLGFFRSVRAKERAGKEPLLSTALFRDRTSNLGLVTQN
                     VQWLLLMGSSFTVAAYLQVVRGYDAVQTGVIFTAATLGLLVSSLAAERLAQRWPQRTLI
                     VTGFLATLAGIVVLIALAGSSPNPWALTPGLLLIGLGLGVMLTPSVNVVQSSFPEEQQG
                     EISGLSRSVSNLGSSLGTAVAGTILVAGLSTGAYAAAMIALAVIGLVGLAAALLLPRTP
                     AR"
     gene            complement(15819..17171)
                     /locus_tag="IE248_RS10455"
                     /old_locus_tag="GCM10010336_21240"
     CDS             complement(15819..17171)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433022.1"
                     /locus_tag="IE248_RS10455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21240"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_190030564.1"
                     /transl_table=11
                     /translation="MPEDTAGSGFARLLRELKDRSGLSYGTLAKRLHMSTSTLHRYCTG
                     DVVPTEYAPVERFARLCKASPEELLELHRNWVLADTNRPRRGAGEAEGPARAAAAPTPP
                     SSPPSPSPQESGPGATQESAPADTAPAAAAAERRRRPRAAALAGIAAVVVAGTIGAVAL
                     TAHLTSRDADVRDRPAAAASPAPGAGKRADGRTASPAPSAPSPSASAPAGAGTSAPPAP
                     SGSGSGPTPGSGSAPGAPAGDGAVSGSPVRVTAQPYTWESPCGQHYLIEKPPSEVGPPP
                     LERDAPAWVAASRAVSAGEQYVTLTLQGSGKETVVLDGLTVRTVGKHAPLAWNDYAMGY
                     PGVGCGAGVPTRSFTVALDAARPAVVPAPDQPDFPFKVSESEPEVFYVKADASKYDVSW
                     YLELSWSSGSRHGTLTIDHNGKPFRTSGLGGRPGYEFPLGGDGWVKAGTTS"
     gene            17385..18149
                     /locus_tag="IE248_RS10460"
                     /old_locus_tag="GCM10010336_21250"
     CDS             17385..18149
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433021.1"
                     /locus_tag="IE248_RS10460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21250"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_190030565.1"
                     /transl_table=11
                     /translation="MSAFRSTPPTSTSRATLPRAGRRLGGAAALALAALALTACQDGKG
                     LQDEGAATFSDSAVATPSATATPGAGSGSASGSASGSATKTGSATKSGGAKATGGDAKG
                     SSDPSAEGDRVTCNGSNTAVTVQAVSRPLNHMLITVKNTGKKNCDLTYYPVLRFDEMQW
                     APAARKDTQPQAVVTLAPGQSGYAGALLSAADGSGEGGVTGHRLTIAFQGRTPHSDGGA
                     SAVPSLPAAGVYYDSSLTVTYWQQSASDALGS"
     gene            complement(18144..19556)
                     /locus_tag="IE248_RS10465"
                     /old_locus_tag="GCM10010336_21260"
     CDS             complement(18144..19556)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606826.1"
                     /locus_tag="IE248_RS10465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21260"
                     /product="S9 family peptidase"
                     /protein_id="WP_190030566.1"
                     /transl_table=11
                     /translation="MTYISGDRESGPTRRALLVAGAGAALAAGCAPGGTPGAPAPTPSG
                     SAPSGLASATGPTPGAMTLFKDPGYNFNGLLALGASGAGAAEVGEVLTAVNAINGAGLS
                     AQTYVETFRKLGDQLLGPPPGSPADAQTKRFRALRAAQYYGQALFFVLGSKDPGSEEQL
                     YKAGRDAWDAFCDLCEPAPVKAAVPYGTTPLPVWFFRPDTSNTPRPTVILTNGSDGQNV
                     DMWTYGVPAALERGWNALVYDGPGQGQLLFVDRVVFTPTWEKVVSPLVDWLSARPDVDQ
                     DRIALTGLSMAGDLAPRAAAFESRIAALVAMPGCVEPWLGFPPEIREILTPSKEETNDI
                     WNTKVVPELPPEAAAVLKKRFEPFSIPAMLQARQGKLFTDFYTPATRIQALSIASVVSR
                     IKAPTLVLDYEDEQFYPGQPRQLYDALTSPKDYLKLTAAQGAQLHCSPMAPQLHCEVVF
                     DWLQETLPGGGS"
     gene            complement(19663..20379)
                     /locus_tag="IE248_RS10470"
                     /old_locus_tag="GCM10010336_21270"
     CDS             complement(19663..20379)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE248_RS10470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010336_21270"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_190030567.1"
                     /transl_table=11
                     /translation="MRWNGVDFTVDGREPTTAEEFHRIGLHCWQDPRHREAAAFFLEPA
                     ARAGHTEAAELLGHVLFSRGEYAAAAPWLRGSAGTSRRAAHYLGRLSYDGCPPAGITAS
                     YADAAHWYREAARLGEPEAMLALGEMYLERLLPLTGAPVAHALELFAAAAELGHPYAQF
                     RSAELYRTDFAAPDPAARCYELCLANPATAAHPLGSLMTQQSRWHLSHIRAAGDADRSG
                     RERDRLHPRPPDEPRY"
     gene            20676..21146
                     /locus_tag="IE248_RS10475"
                     /old_locus_tag="GCM10010336_21280"
     CDS             20676..21146
                     /GO_function="GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063518.1"
                     /locus_tag="IE248_RS10475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21280"
                     /product="Dps family protein"
                     /protein_id="WP_100580988.1"
                     /transl_table=11
                     /translation="MSVVKNALPEADLKVVGEALQGALVDLVDLGLVAKQVHWNVVGPR
                     FRSVHLQLDEVVTSARTHSDVVAERASALGITPDGRAATVASSSAISGVPEGWVKDVDA
                     VRILVDGLSAVITRMRERIHATADPDPVTQDILIAVTGDLEKHHWMFAAESA"
     gene            complement(21174..21962)
                     /locus_tag="IE248_RS10480"
                     /old_locus_tag="GCM10010336_21290"
     CDS             complement(21174..21962)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-114). E-value: 6.4e-09. Score:
                     27.9. Matches aSDomain:
                     nrpspksdomains_IE248_RS10480_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640254.1"
                     /locus_tag="IE248_RS10480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21290"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190030568.1"
                     /transl_table=11
                     /translation="MLIDLSGRTALVTGSTQGIGAAIAAGLAAAGARVAVNGRSRASVE
                     EALARLRASGGEFVAAPGDITTDEGARSVFEAVPRTDILVNSLGVFGPAKALEIEDDEW
                     RRYFDTNVLTAVRMIRRYLPGMMERSWGRVQNIASDSAVAVPAEMIHYGMSKTALLAVS
                     RGFAKEAAGTGVTVNSVIAGPTHTRGVEDFVYELVDRDLPWDEAQRAFMRTHRPQSLLQ
                     RLIEPEEIAHMVVYLSSPFASATTGGALRVDGGYVDSILP"
     aSDomain        complement(21621..21938)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10480_PKS_KR.1"
                     /evalue="6.40E-09"
                     /label="IE248_RS10480_PKS_KR.1"
                     /locus_tag="IE248_RS10480"
                     /protein_end="114"
                     /protein_start="8"
                     /score="27.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGSTQGIGAAIAAGLAAAGARVAVNGRSRASVEEALARLRA
                     SGGEFVAAPGDITTDEGARSVFEAVPRTDILVNSLGVFGPAKALEIEDDEWRRYFDTNV
                     LT"
     CDS_motif       complement(21843..21932)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10480_0001"
                     /evalue="6.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE248_RS10480"
                     /protein_end="40"
                     /protein_start="10"
                     /score="15.6"
                     /tool="antismash"
                     /translation="LVTGSTQGIGAAIAAGLAAAGARVAVNGRS"
     gene            complement(22137..22538)
                     /locus_tag="IE248_RS10485"
                     /old_locus_tag="GCM10010336_21300"
     CDS             complement(22137..22538)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389602.1"
                     /locus_tag="IE248_RS10485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_21300"
                     /product="hypothetical protein"
                     /protein_id="WP_229895238.1"
                     /transl_table=11
                     /translation="MSLPYRTVALPPVDGTVCDPAPPPPQPWTGVVRGVPAGEGRGPGA
                     REGGREAAAGVETCGLEAEGDAEGLAEAEGEPEPETEAEGEAEALGERNTVGADRATGG
                     FGRVEPATKSTVAMTAVTLAAVQDTHMSR"
ORIGIN
        1 agcggaccat caccgtggcg acgctgagca agggcttcgg ggccggcggc acggcgatcc
       61 tgctcgacgg ctaccccgag cagacccggc ggctcatcga gcggttcgcc ggaccgctgg
      121 gctactcgca gaagatgaac gccgccgcgg tcggtgcggc gctcgcctcg gccgagatcc
      181 accgcaccga ggaactcacc ctgcttcagg ggcggctgcg gtccaacatc gcgctgttcg
      241 actcgctggt cgcgaccgag cagtccgaca gcacctaccc gatcagggtg gtgccgatga
      301 ccgacgagac ggtcatcgac gccgccaagc aggtcttcgc ggccgggttc tacacctcgc
      361 cggtgttctt cccgatcgtc gcccggggca ccgccggact gcgcgtgatg ctccgggccg
      421 gccagagcga ggagcagatc aggcggctct gcgcggcgct ggtccgggcc ggagcccgcc
      481 cggcggccgc ggcacccgcg ccgggaacgg gcggcgaaca cctcgccgcg acgacagggg
      541 aaggagcgcc ggatggacac gcatgaggac ctcggcacgg gaagcgggca cccgtggttc
      601 ggccgtcacc ggctgcggcc cgcagcgccc gcggacacca tccggcggat gctgcggcac
      661 gagctccggg acaccggctg gccgtaccag cgggtcctgc ccgcggcgcc gatggcgatc
      721 ccgcgggcgt cctacgccga gatcttccgg gtgagcgtcg cgctgatcga gctgctgcgc
      781 cgtaccgccc tggagagcgg acccaccacc gccgaccggc tgagcgccta cgacatgccc
      841 gccaccgagg accggctgtg gatgggcgac cccttcatcg aggagcggta cgccgactcc
      901 gtggtccgtc cggacctggt catcggtccg gacgggccgc ggttcctgga gttcaacgtc
      961 agcggcgcgc tcggtggcgt ggtggagacg cggagccggc tggcggtgtg gcgcgggctc
     1021 cacgccgacg aggacggccg gacgccgttc cgctccccgg acccgttcga cgtccgcgcg
     1081 gacatgttcc ggtcgctcgg cgcggagctc gggctggcgc cgcgggtggc cgtcgtcggc
     1141 agcgcccggg tgatcggcgt ggagcggcgg tacttcgaaa tggaggccga ccactacaac
     1201 agccacggcc tgaccgcccg cttcttcgag ccggaggagc tgcccgaggc gtgggactgc
     1261 gccccgcacc tgcgccatca ggtcgggctg cgcaacttca ccatcccgga ctggctggag
     1321 gtgggcatcg acaccacgcc ggtccaggac gccctggaca acggatgcct gctggtgggc
     1381 acccagacct cgaccttcat gcacagcaag ctgaccatgg ggctgctgtc ggagggacga
     1441 ccctggatga ccgcggccga ccgcgggctc gtcgagcggt acctgccgtg gacgcggatc
     1501 ctctcggagc gcaagaccga ccgggagggg cagcaggtcg acctgctccc gttcgtgctg
     1561 ggcaaccggg agctgctggt gctcaaggcg ggcctggggg agagcgggaa gcaggtcgtc
     1621 atcggccgcg aggtcgacca ggccgggtgg gagtccgccg tcggcgcggc cgtcgccggc
     1681 ggtaccagcg tggtgcaggc cttcgtggag ccgcagacct gccgggtctc gctgatcgcc
     1741 gacggctgcg acgagccgta cgacgcggat gtcgctccgg tcctcggccc cctggtgttc
     1801 ggcggccgcc cggccggact gttctgccgg ttcttcggcg acggcagcgc ggggatcgtc
     1861 agcgtccggg gagggacgag cagctccgac aacgtgatgg tggccatctg acggcgccgc
     1921 ccccgcccgg acgccccggt ttcccgcgcc gccggtgcga cactgatggt gtgacgcacg
     1981 gcgaccggga gactgagcga cgtttggagc gggccatcct ggagctgctg gagggtcgcg
     2041 gccccaccgc gacgatctgc ccgtcagacg ccgcgcgggc cgtgtacgcg ggcagcgacg
     2101 acggctggcg cgtgctcatg gaaccggccc gccgggcggc ccggaggctg gtcggcgcgg
     2161 gcgaggtgga gatcacccag gccggccgcc ccgtcgaccc cgctacggcc cgcggaccgg
     2221 tccgtatccg gaccgcccgc cgacggccgt aatcagccgg ccggcgggct cagcggcggg
     2281 ccgcgaccgc cgccagggcg tccttgacct cctgcgccac gcgggccgcg tcctcggggt
     2341 tgttcaccac gtcggtgcgg ttcatgtcga tgacgaggac gtcactggcc gagtagtgct
     2401 tgtgcaccca gtcgtcgtag ccggaccaca gcgtccggta gtactcgacg agggcctcgt
     2461 cctgctcgaa atcgcggccg cgcaggccga tgcggtacat gaccgtctcg aagtccgcct
     2521 tgaggtagac catgaggtcg ggcgccttgc ggtacggcag gccctcgatc tcgcgcatca
     2581 tctcgcccag cagcccctcg tacacctgca tctcaaggga gctgatccgg cccaggccgt
     2641 ggttgacctt ggcgaagtac cagtcttcgt agatggaccg gtcgaggacg ttgtcggccc
     2701 ggtggtacgc gtccttgatc gcggcgaacc gcgtctggag gaagtagagc tggagcagga
     2761 aggggtagcg cttggcctgg atctcctcgg ggctcgccgt gtagaagagc ggaaggatcg
     2821 ggttgtcttc cacgctctcg aagaagacct cgctgcccag ctccttggcg atcagttcgg
     2881 cgacgctcgt cttgccgatt ccgatcatgc ctccgacgca gatcactagc atacctcact
     2941 tctccctggg ggtcttctgt tcctgggccg gcgcgcgggg cgtcccacgt caatgagacg
     3001 cacgccggcg gtcacgcgat tccccgggat cttcgtgatc agcgccatgt ggtcctcgtc
     3061 cggaccacgg ctctgaccca ggccgctctc ctcgacgcgc acggcgacga gccgcaggtc
     3121 cgcggccgtc ctgaatctta agtgatgatc cgccccgcgc gggccagagc gggggcggcc
     3181 aagaccgggc gtcagcgccg cccgccgaac tcccacgggt ggatctcgat gtccgcgtag
     3241 cgctccacgg ccaggacgcc gcgcgccgcg tcggcgtccg gggcccggac cagcgccgcc
     3301 gtacccagcc aggtggtggc gtcgtcggac agcagcgggc cgtacgcgat caggtcgtcc
     3361 cggcagccgg gcgccgcggt gaggtcggcg gccccgcccg cgccgagccc gaggaccagg
     3421 taccggttgc ccccggtccg gccgccgggg aagtcccaca tggtgcgccc cagcatgtcg
     3481 cgccagcgca gcagcagcac gtcccggtac acgccggcct ggtagccggg ctcgtcgaag
     3541 gcgaacgcgc gcgcggcggc cggatcgggg aggtcgacga tgtgcacgct gccgctgggg
     3601 gcgtcgccgc cgggggcgaa ggtcgggccc cgggcgatca gctccttctc gtactggtcc
     3661 atgtaggacc agtggcgttc cagcagttcc atgcgcaggg ccgtggagcc ggggcgatcg
     3721 cggtggtagc agaagaattc catgctgctg gactctctcc gagaaccggc cgaagatcaa
     3781 cggtccgggg ccggtgaatg ccgcccggat gccggggtag ggggatccgc accagcccga
     3841 tcgaggaggt cgaagtgagc gtcgaggacc cgtccggcaa acgagctcag gagatgcgcg
     3901 acaaggcgca ggagctggag caggccgccc agtacgccgc cgatcccgcg gagcggcagc
     3961 ggctcacgca gaaggcgctg cacatccgcg agaagagcga gcaggtgtac ggcttcggcg
     4021 ccgggaccat ggaccccatg tagcccggac gcggccggcg gttcaggtgg tcgcgggagg
     4081 ctgagcgttg accactccga aagggacgtg cacgctcggg gtgccgtgcg ccgtgccgtt
     4141 caggtgggag acctggtcgt cgaagaagat gtgcgggtcg agggtgcgca tcaccgccgc
     4201 cttttcgatg ccgccgagga agaaggcgtc gttgacccgt agcccccagt ccttgaggct
     4261 ccgtatggcg cgctcatggg tgggggcgtc ccgagcggtg accagggaca cccgaaggcg
     4321 cggctgatac gcgggatcgc cgcgccggcg ctcctcctcc cggcgctgga tgcggttgac
     4381 gcccgcgagg aaggggcgca gcggtcccgg atcgtggggg gtggcggcct cgcggacctc
     4441 gtgcgcgcgg aactcgtcga gtccgaggct ctggaagacc cgctcggagg cgtcgcccgc
     4501 cagcactccg tcgaagtcga aggccatgcg gagttcgggg tcgctctcgt cgtcgatgcg
     4561 cgccgtgtgg agcacgtggc cggcgggcag tcccgccgcg accgcgtccc ggacgtcggg
     4621 tccgttggcc gacaggaaca gcgacatgtt cagcgcgcgc atgaaggagt gcgaggggcg
     4681 gccctgccgg aacaccgccc ggctgatcgg caggtggtgc gccgtgatcg accgcatgac
     4741 ccgcagcccg gtgtcggggt cgttgcggga gaggatgatg acctcgacca gggggtcgga
     4801 ccggtccgag aggtcgttca gcgacagcag gcgtctgacg aaggggaagg ccaccccctt
     4861 ggccagggcg tggtccgcgt gcgcctcctg gtaggcccgg taggcgtcct ctccttgctc
     4921 ccggaacacc gcgtcgcagt cggtcaggtc gaacagggcg ctggaggcga tccccaccac
     4981 caggcgaccg gacaggtcgt accgcatgaa gccccccgtt gaacgcgatc ggaacgatgg
     5041 ggggcttatc gccctccggc atatgcggaa aacgtccgcc ggggtgattc tgaggtcccg
     5101 gacgggccct cggcggcccc cgggcggtgt gcggagccgc acccatgcgg gcggaatcag
     5161 cccatccggt tgttgggtcc gcgctccggc gggcgggggt ttcgcgatgc ctgccgaggt
     5221 cgggcggccg tgggctgcgc gggagcggcg ggaggcgggc gtcaggcttc ggccacccgc
     5281 tcccgcgcgc cgcatgccgt gacgttcccg cacggcactg gctgggcagc cggttggtgc
     5341 tgattgatcg tcacgtgagg ggaaccgcga tgaccaaggt tctggtgctg cacagcgtgt
     5401 gtctggtgag gtccgccctc gccgcgctgc tgagaaccga gggtgacttc gatgtcacct
     5461 cctgcggctg gcgcgccgcc gggcgccagg cggcgtcctt acggcccgac gtggccgtgg
     5521 tggacctcga ctgtccgggg gcgtcggcgg ccctgctcgc ggacgccgac gccgctcgtc
     5581 cgctcccgcg ctccacgccg ctgctcgtcc tcgcccgcgc cgacaccccc ggctcgctgc
     5641 ggcgcgcctt cctgacccag gcgcagggtt acgtcgacaa ggacggctcg cccgcccggc
     5701 tggtccgggc catcggcagg gtcgcggccg gggaacgctc catcgacgcc acgctcgcct
     5761 cggccttcat ggaggccgac cccatgccgc tcagcccgcg cgagctgagc gtgctggccc
     5821 gggccgccga gggcgactcg atcgcggaga tagcccgcgc cctgcacctc gccagcggaa
     5881 ccgtacggaa ctacatggcc gccgtgacgc ggaagaccgg cgcccgaaac cggatcgatg
     5941 ccatccggat ttcccggcgg gccggctggg tctgagaccc cggcgccggt tcccccgaag
     6001 cccgcttcac ccccgcgcgt tccacagacc caccagatcc cggtacaggg gcgacctggc
     6061 cgggagctcc gcatgcgtgc cgcacaccgc ccgggtcccg tcgagtacga ggacccggtc
     6121 ggccctggcg gcggaggaga tgcggtgggc gaccaccacc agggtcccgg ggcgcgcggc
     6181 gagcgcccgc tcggcgcgtt cctccgtccg caggtcgagg tggcaggtgg cctcgtccag
     6241 caggagcagc ggggcggggg agaggtaggc ggcggtgagg gcgaggtgct ggcgctcgcc
     6301 cggcgagagc cgggccgggt cgacggcccc gtccagcccg ccgagccggt ccacgagccc
     6361 gtccgagccg agggcggccg tggcccgctc cacctcggcc ccggataccg ggccggggca
     6421 caggtgggtc aggttctcgc ggaccgtccc cgtgaacacg tacgcctgct ggggcaacag
     6481 ggtccgccga agatcgggcc cgggcccggt gacgccctgc gcgggggcac ccgccacccg
     6541 tacggttccc ccgccgggcg gcagcaggcc ggcgatcagg gcggtgagcg tggacttgcc
     6601 gatgccgctc ggccccacca cggccaggtg ctcgcccgcc ccgaccgtca ggtcgagccc
     6661 gtcgatcacc ggctgcgcgc ggggcccgta ggcgaaccac accccccgca gctcaacggc
     6721 gacacccggc ccggccccca cgccgggggc cgcctccggg gccgtggtcg cggcggggga
     6781 gtccgattgg ggggtgcaga agcggtccag taccaccagg agccgggtgc ccgccgcgcc
     6841 caccgccgtc atcagggcgt ccagggcggg cagcagcgac tgcacgaggt aggtgagggc
     6901 cccggccacc gcccccgcgc tcaccccgcg cccgagcagc cacggcgtcc cggccagcag
     6961 cgcgacgacc ggcaaccggc cggcgacgcc cagggccagc gtgcgcaggg cggtccagcg
     7021 cgcgaggcgc ccggtcagcc gctcctgctc ggcgatcagc cgctccaccg gggctccggc
     7081 gctcgccccg ccgccgcagg cgacgacgtc gcgcagcccc gccgccagtt cgccggcgcg
     7141 cccggacagc gcctcgtcgg cgtcgagcgc cgcccgctgc acgcgcgcca tcgggcgcaa
     7201 cgtggccagg aaccctgccg tacccaggag cagcgcgggc agtacgagga ccagcaggac
     7261 gggatccagc gcggccagcc ccagcagcgc tcccagggcg gtgaagacga acgaccgggc
     7321 gaccaggacc agtccggcga aggagtcccg ggccatctcg gtctgctgcg tgagccggga
     7381 gacggcgccc gcgtcaccgg cccgcccggg gtcggcgacg gcccgcccga tcgcctggcg
     7441 tacggaacgc cgcaccaggc cgtcccgcag gggctcgacc aggtcggcga gcccgccgaa
     7501 cactccgcgc agggcgaggg caccgagcag ggcccccgcg ccggccacgg ccagccagcc
     7561 gagtccggtg ccggtgcgcc cggcgaggaa gccgtcgtcg agggcgcggg cgaccgcgta
     7621 gccgccgagg aaggtgtgcg cggactccag cagggaccag agcgcgagcc gccgcagcga
     7681 ccggtaccgc ccgcgcagga agcggcggcc ctcgcgggac acccggcgcc aggagccgtc
     7741 cccgctcatc ggaccgtctt ccggccgggc gcccgccgcc cgccgccgcc cgccgcggcc
     7801 gaccccgttc cggcactcgc tcccgcgtcc ggcccctcgc ccggcgccgc acccgttcgc
     7861 gggcccgctg ccgccgccgg ccccgtgtct agttccgagc ccgttccttg ggcccgtgcc
     7921 ggggccgcgc ccgttgccgc gtcggagccc gtgttccgct gcgcgcctgg tcttccggcg
     7981 gcaggcggtg ccggtgccgc cgccagtgcc gaggccgccg ctggcttcgt gtccggttcc
     8041 gagcccgttc cctcggcccg tgccgccgcc gggtccgtgc cggtggcgaa caccgcgcgg
     8101 taggccgggt ctcgccagag ctccgtgtgg gggccggtcg cgcggacgcg tcccgcgtcg
     8161 agccagacga cgaggtccgc gcgggcggcc gaggagatgc ggtgggcgac gacgaggcgg
     8221 gtgcccgggc ggacgtcgtg ggtcagggcg cgctccacct cccgggcggt gagggtgtcc
     8281 aggctcgacg tcgcgtcgtc caggacgagc agccgcccgg cgcggcagaa cgcccgcgcc
     8341 aggcccaggc gttgcagctc cccgccggac agtggcgcgt ccggcagcgc cgtgtcgtag
     8401 ccgtcgggca ggcggcgtac gaaggcgtcc gccccggccg cccgcgccgc ggcgcgtacg
     8461 ttctccgggg tcggcgccgg cccgctgccg aatgcgatgg cggccgcgac gtcctccccg
     8521 aacagggcgg gccgctcgaa ggcgtggccg acctcccggc gcagctcccc ggcggacagt
     8581 tcgtccagcg gtacgccgtc cagcaggacc cgccccgcgt tgcaggcggt gagccgcccc
     8641 gccaccgcgg ccagcgtcgt cttgccggag cccgagcggc cgacgacggc cgcggtcgtc
     8701 ccgccgggga tccgcaggtc gatgtcgcgc agcaccgcgg tgcccccgcg gaggacccgc
     8761 accccgcgca gctccagcgc gcccggcccg cccggtggca accggcgtac cccctggggg
     8821 agttccggca gttcgaagag ggccgccgtg cggcgcgcgg cggcgcggcc gcgcaccacc
     8881 gccgccagcc gccccgtcac ggcgccgacc ccggccgcga gtcccgcgta gcggaccgcg
     8941 gcgaggagcc cgccgacgcc gagggccccc tcggcgaggc ggaccccgcc cacgccgagg
     9001 acgacgtaca gcagcagcgg catcagggcg cccgtgcgcg ccatggtcgt gccgtagatc
     9061 cgccaggtct cccgcccctc ggcgccgagt tccgacaacc ggctcagcac gcgcgcctgt
     9121 tcgcgctcgg cggtgccggc ggcggcgatg gtacgggcgc ccgcgagggc ctccacgagg
     9181 cggccggcca tcgcgagctg tacttcctgg taacggccca cactcgcccc cgagtcgcgg
     9241 gcgaacgccc tcaacagcag cgccaacaag gggagtccgg cgaggaacgc cagcgcggtc
     9301 catacgtcga ccaggaccag cgccacgagt ccgccgagcg gcgccagcag ggccacggcc
     9361 gcgcccacca cggccgccgg tacggcgccg gcggtggtgg cctgggcggt cagccgggcg
     9421 gagagctcac cgggggagtg gcgggcggcg tggtgcggcg cggcccgcag cagccggccc
     9481 agtcccaggc gccgcagcca ggcggtggag cgggcgtcga cgccgccggt gaggcgggcc
     9541 gtcaccgcgt cgagcagtac ctcggcggcg atcaccgccg cgcaccacgc ggtccaccgg
     9601 gcgccgccgg gatcctgtcg cagcagcagg tcgagggtgt ggccgaggac cgccggttcg
     9661 gccagggccg cgcaggcggc ggccaccgaa cagacggcgg cggcggcgag acggccgccg
     9721 ctgtgtcgcg cggccgcccg cagcgcccgg tcggcgccgc gggcggcctc cgcctcacgg
     9781 gtgggatcgg gtgcggtcat gggcgacggc tccaggggtg tggtgcgggc ccgggcggag
     9841 aaccgcccgg gcccgatagg acctgactag ttacaggtcg tgatgctcag gctgctgtcg
     9901 ccgcagagga gcaggctggc gcggctgccg ccaccgccac cgtgcgcggc ctcggtggtc
     9961 tcttccttcg gggtttccat cgactgcagg tcgagaagcg tcatgtctga ttcctcttca
    10021 ctgtggtgtt ccgatgggac acggccccca cgagggggac cggctctggg gccgccgcgg
    10081 ccgaccgcgg cggcgggagg aacggcagct gtgcgcgccc gccgggcgcg gcgctgccga
    10141 gggcgaggag cgcgccggcc gtgcccgtgg acaagtccat ggacaggcgc atcatctgct
    10201 cgccggggaa ggccaggaag ccttggtacg ggaccgcgtg ccgggccagg gcctccacct
    10261 gccgggcgat gtcctccggg ccggagcccg ggcccggggt ggtggtgcgc gccaggtgga
    10321 ggatcattcc ggcggcgccg cggaacaggc tcggctgcgc gtagaaggtg gcctgcgcgg
    10381 cgcggacgat ctccggccgg gcccgttcga agcgctcgtc cggggtgtgg gccggccagt
    10441 cgtccagcac catgccgatc cccacgctgc cggccccgag gtagggcatc gtgcgccacc
    10501 cctcgtcgac ctggagggtg ccgaagacgc tggtcacaca gcggtcgaga tcgcggtgca
    10561 gggcccggcc ggcccggagc agtgactccc ggtcgccggt gcgttcgtag agccgcaggt
    10621 ggagcagcgc gggtccgctg tgaccgtgga gcagaccggc ccgtttcgag ccggcggcgg
    10681 cctcggactc cgcgagcaga tcggcgcagc gcagggccgc ggcgtgcagt gcgctctcgc
    10741 cggtggccgt gcccagggag tccagggcca gcccgatgcc cgcgagtccg ccgtgcaggt
    10801 cggggccggc cgactgccag ggatggccca gcagttgttc ggcgagggcg agcgcgcggt
    10861 cgcggtggcc gagccgctcc agggtccacg cgataccggc gaggccgtcg tagaagccca
    10921 gcggcatgcc ggaggccggt tccttcgtcc gggccagcag ccattcctcg gcttcgggcc
    10981 acgggtcggc gccggtctcg gcgagcgcgt acagcacacc ggcggccccg tagccgaaac
    11041 cggtgccgcc gccggcgttc gcgaactggg cggtgtcccc ggggaagagg cggtcgtcgc
    11101 ggtcgaaggt ggcgctggcc ctgatcgccg ccgtcatcga ggcgcgggcc gcctcccagt
    11161 cgcccggctc gaccggcaga taggggcggc ggggcaccac cgcgggtggg gcgccctccg
    11221 ccccggcgag tatctcccgt accgcctcgt cgaggaactc gcggggtacg ggaaactgct
    11281 cggcggcgat gtcggccagg tgcgcggcct tgccccggtc cagcaccagc aggctggtca
    11341 gcggcaggaa cagggccagg cgcaggcagg ccagggcgta ccggtcgacg gcgacgccgc
    11401 gccggtccgc cggggcgacg aacgccgggt tggcgacggt ctggcgcagc ccctcgtcga
    11461 cgtgcgcggc ggcctcgaag tcgaggagcg acaccgacgg ctcgccggtc tcctcgtcct
    11521 ccgcgaccat gatgttgaac aggtgcaggt cgttgaagac gatgccgcgg gcgtgcaccg
    11581 cctccacggc ctccgtcacc cgccggtgga tctccagcgc ccaccgcgtg tactccgcga
    11641 gctccgcggg gtcggggtcc gcctcgatca gcgggtgccg gcgggcgaag taggtgttga
    11701 ggggtttgcc ctccaagtac cgcatcacca ggaagtggtg gtccccgacg gtgaaggtgc
    11761 cgtgcaccgc gggcacgcag tccagcccgg ccagctgctc cagggcccgg cgttcgcggt
    11821 ccagccgggt cacggcgtcc gccccgtcgg ccgcgagccc cgcgaagggg cgcgcttcct
    11881 tgaggacgac cggctcgccg gtgcggacgt cacggccggc gtagacgccg cccccgttgg
    11941 agaagtgcag ggcccgctcg acggtgtagg gcaggccttc gagggtgacg gccgcccgct
    12001 cggccaggtg gggcgccagg aaggcgggta actcgaccca ttccggcgtc tggaacaccg
    12061 gcccccgcgg gtccggaacc agccggccgt ccggggcctc gatcgcggga acgagctcgc
    12121 cgcggtcgtc gtagcagtgc cgcagcgtga aactgccgta ccgcaggtgc acgggaccgc
    12181 cgttccagcg caggtcgctc aggatgtacg ggccgggctc gccggccagc agcgcgtcga
    12241 gctcctcggc gatgcgcccg cactgctcct cgtccgccgg gtagacggtg aggaacttgc
    12301 cgctcgcggc gcggtccgcg tacttcgcgt tgcgcaggtg caacaggtac cggctcggaa
    12361 cgaacttgaa ggcgatccgc cgctccacgc agtaccggta gacccgttcg aggaccgact
    12421 cggcgttgtc gaggcaggcc gagacatgga tcttccagcc ctgcgagggc agtcgggcgt
    12481 ccagggggcg cagcgccagc cagtccccgc tgcggtgcgt ctgccacccc gccggtacgg
    12541 gggcgagcgc ggccgggtag ttctcctcgg cccgccggta cggcgcgtcg tagaaccagc
    12601 ggtcggcgtc gcagaaggcc gcgtacccct tgttcactcc tgctcccttg gtcggtgacg
    12661 tgctcacgct gtcacgcggc ccgagggccg cgacagtcac ggctgtcact tccggggtgt
    12721 gcagtacgca cgagtcacaa cgggtcgccc atgctctcga tcggcgcgat cgccgcgacc
    12781 gggcggaaac aaaccgggcc cggaccgccg ggtcccgcgg gccgggtggg ggtggcgctc
    12841 gtaggctgaa gagggtgtac ggctcctgtc cggcagccgg tgggccgcgg gaaggtgagg
    12901 catgggaagg cgctgggccg cacgtctgtc actggccgcg ggcgtggcgg cgctgctggt
    12961 gctggtggtc ttcggcgggc tcgtcagcct cgtgctcatg ggcgtgggct gggcggggct
    13021 ggcgctctcg gctgcgggcg tgtggtggat gctcacccat accggccgga tccgggtgct
    13081 ggccgtgctg ctgctggtgg ccgtgccgct cgccgtgctc gccctgtacg ccgccgcagg
    13141 gctgctgtgg gtcgtgctgg tctcgctcgg cctgtgggcg ctggccgtct tcgcgggccg
    13201 ggccgcgctg gtcgaggacg ccccgccggc catgcccgag caccccgccc gcaggcccga
    13261 gcggccgttc ctgatcatga acccgcgctc gggaggcggg aaggtcacca agttccggct
    13321 cgccgagcgg gccagggccc tgggggccga ggtcgtcgta ctggatccgg accggccgca
    13381 ggacgtggcc cagctggcgc gggaggccgt ccggcgcggc gccgacctgc tcggcgtcgc
    13441 gggcggtgac gggacccagg ccctggtcgc cggggtggcc gtggcgcacg acctgccctt
    13501 cgtggtgatc agcgccggca cccgcaacca cttcgccctg gacctgggcc tggaccgcaa
    13561 gaaccccgcc cggtgcctgg aggcgctgac cgacggcgtc gaactgcgcg tcgacctcgg
    13621 atacctccgg gcggggggtc ctgaggagcc cgaggagccg gcggagcccg gtacggaggt
    13681 cgtcttcgtc aacagtgcct cgttcggcgt gtacgcggag gtggtgcaga gccccgccta
    13741 ccgcgacgac aaggtccgca ccatcctgga gatgctgccc gacctgctgg cccaggagag
    13801 cggcgcgcgg ctgagcgtgc gtggcgacgg gccggtcctg gaggcccccc aggccgtcct
    13861 ggtgagcaac aacccctatc agcggggcga ctcggcggga ctcgggcgcc gggagcggct
    13921 ggacaccggc gagctggggg tgctgggcgt ccacgtcggc agcgccgccg aggcggcgga
    13981 gctcctgctg cgcggcgggc agcagggccg cgggctgacc gagaccaccg cccgggaggt
    14041 cgtcgtcgac gccgacgccc ccgtcatccc ggtcggtgtc gacggggagg ccctgacgct
    14101 gcccactccg gtccgctgcc gcctcgcgcc cggcgccctg cgcgtccgcg tgccccggca
    14161 ccggccgggc gtacggctgg gcgcgccgcc gatggactgg cgccgggtgc ggcggctggc
    14221 gctgaccatg ggccgggccg ctgcgggccg cggtcccgcc tgaccgggcg agagcggggg
    14281 aggggcggtc accgcgccgg agtccgcggc aggagcagcg cggccgcgag cccgacgagc
    14341 ccgatcacgg ccagcgcgat catcgcggcg gcgtaggcgc cggtggagag gcctgcgacg
    14401 aggatggtgc ccgcgaccgc cgtgccgagg gaggaaccga ggttcgacac gctgcgggag
    14461 agcccggaga tctcgccctg ctgctcttcg gggaagctcg actggacgac gttgaccgag
    14521 ggggtcagca tcacgccgag acccagtccg atcagcagga ggccgggcgt gagcgcccac
    14581 gggttcgggg agctgccggc cagcgcgatc aggacgacga tgccggcgag ggtggcgagg
    14641 aaacccgtca cgatcagggt ccgctggggc caccgctggg cgaggcgttc ggcggcgagc
    14701 gaggacacga gcaggccgag cgtggcggcg gtgaagatga caccggtctg gacggcgtcg
    14761 tagccgcgta cgacctggag gtaggccgcc acggtgaacg aggaccccat cagcagcagc
    14821 cactggacgt tctgcgtgac caggcccagg ttggacgtcc ggtcccggaa cagggccgtg
    14881 gacagcagcg gttccttgcc cgcccgctcc ttggcccgca cggagcggaa gaacccgagg
    14941 agcacgaggg cgcccagggc gagcagggcg agggtgagcc acaggctgtc gtcggccgcg
    15001 aggatgccca tgacgacgag gatcaggccg gcggcggaga ggaccgcgcc cgtggtgtcg
    15061 aaggagcggg tcggatcggg cgggagcgga tcctccaggc ggcggctcag caggatgatc
    15121 acggcgatga ccagggcctg gaagacgaag gcggcccgcc agctcagcgc cgaggtgatc
    15181 agcccgccga tgagcggccc ggcggccgcg ccgatgccgc ccagcgccat gatgacgccg
    15241 aaggcccggg cccgggaggc gaggtccgtg aagatcagcg tcgtgaggat gtagacgggc
    15301 gggatgagca gggccgtccc gatgccctcc aggatcgagt tcccgaggat cagtacgccc
    15361 aggcccgggg cggcggcgct cagcagcgcg ccgatgccgt agacgacgag gccgaccagg
    15421 aggcagcgct tgcggccgta gcggtcggtc agtttgccgc cggggatcat cagcgcggcc
    15481 atgaccagca ggaagatcgt gatggctgtc tgtactccct ggacggtcgt gtccaggtcc
    15541 tcgctgatgt cgttgatcat cacgttcatg ttggagccgg cgaagctgca gatgaactgc
    15601 gcgagcgcca gcggcgcgag gacccgccgt tgcgcgccgg acggccggcg cggggttcgg
    15661 gtgtcggaca ccggtgtcgc ctccgcatct cgggccgccg ggcctgctgc gcggcggttc
    15721 gtacgcggtg ccgcccttgg cggtacgcac ccacgctcac agcgtgcgcc gtgccggggc
    15781 ggggcgcacg ccgagtgctc cgcaggcgtc cggaacggtc agctcgtcgt accggccttg
    15841 acccagccgt cgccgccgag ggggaactcg tagcccgggc gaccgcccag tccgctggta
    15901 cggaagggct tgccgttgtg gtcgatcgtg agggtgccgt ggcgggagcc gctggaccag
    15961 gacagctcca ggtaccagct cacgtcgtac ttggaggcgt cggccttgac gtagaacacc
    16021 tccggttcgg actcgctgac cttgaacggg aagtccggct ggtcgggcgc gggcacgacg
    16081 gccgggcgcg cggcgtcgag ggccacggtg aacgaccggg tcggtacgcc ggcgccgcag
    16141 ccgacacccg ggtagcccat ggcgtagtcg ttccaggcga ggggcgcgtg cttgccgacc
    16201 gtacggacgg tcaggccgtc caggaccacc gtctccttgc cggagccctg gagggtgagc
    16261 gtgacgtact gctcacccgc ggagacggcc cgggacgccg ccacccaggc gggcgcgtcc
    16321 cgttccaggg gcggcgggcc cacctcggac gggggcttct cgatcaggta gtgctggccg
    16381 cagggcgact cccaggtgta cggctgggcg gtcaccctca ccgggctccc ggacacggcg
    16441 ccgtcgccgg cgggggcccc gggcgcggac cccgaccccg gcgtgggccc ggatccggac
    16501 ccggacgggg ccgggggtgc ggaggtgccg gccccggcgg gcgcggaggc cgacggggag
    16561 ggcgccgagg gcgcggggga ggccgtccgg ccgtccgctc gcttccccgc gccgggtgcg
    16621 ggggacgcgg ccgcggcggg ccggtcgcgg acgtcggcgt cccgtgacgt gaggtgcgcg
    16681 gtgagggcta cggccccgat cgtcccggcc acgacgaccg ccgcgatccc ggcgagagcg
    16741 gccgcgcgcg gacggcgccg ccgctccgcc gcggccgccg cgggcgcggt gtcggcgggc
    16801 gcggactcct gcgtcgcacc cggcccgctc tcctgcggag atggcgacgg cggagacgac
    16861 ggcggtgtcg gggcggcggc ggcccgtgcc gggccctccg cttcaccggc gccccggcgc
    16921 gggcggttcg tgtccgccag cacccagttc cggtgcagtt cgaggagttc ctcgggcgag
    16981 gccttgcaga ggcgggcgaa ccgctcgacc ggtgcgtact ccgtcgggac gacatcgccc
    17041 gtgcagtagc ggtgcagggt cgacgtactc atgtggagcc gtttggcgag cgttccgtag
    17101 ctgaggccgg accggtcctt caactcccgc agcagccggg cgaacccgga cccggcagtg
    17161 tcctccggca ccgatcctcc tacccccgtg tcccgtccgg cgtcccagga acgggttgtt
    17221 ccagcagctc agagcccgtt tcggcgtccc accgtccctg actgcccccg gcgggtggcg
    17281 gctgggacgg atcaccgcac aggctggggc catccaagca caccgctcac ggcgaccggt
    17341 cctgaccgtc cgccgcggcc acgtcacatg aggggtcctc agtcatgtcc gccttccgca
    17401 gcaccccgcc cacgagcacc tcccgcgcca cccttccccg cgccggccgc cggctcggcg
    17461 gcgcggccgc actcgccctc gcggccctcg ccctgaccgc gtgccaggac ggcaagggcc
    17521 tccaggacga gggggccgcg accttctcgg actccgccgt cgccactccc tcggcgacgg
    17581 ccaccccggg ggccggctcc ggatcggcct ccggatcggc ctccggctcg gccacgaaga
    17641 ccggttccgc cacgaagtcc ggcggggcga aggcgaccgg cggcgacgcg aagggctcct
    17701 ccgacccctc cgccgagggc gaccgcgtca cctgcaacgg gtccaacacc gccgtcaccg
    17761 tccaggcggt ctcccgtccg ctcaaccaca tgctgatcac ggtgaagaac accggcaaga
    17821 agaactgcga cctcacgtac taccccgtgc tccgcttcga cgagatgcag tgggcgccgg
    17881 ccgcgcggaa ggacacccag ccccaggccg tggtcaccct cgcacccggc cagtccggct
    17941 acgcgggggc cctgctgtcg gcggccgacg gcagcggcga gggcggggtg accggacacc
    18001 ggctcacgat cgccttccag ggccggacgc cccacagcga cggcggcgcg tccgccgtcc
    18061 cgtcgctgcc ggcggcgggc gtctactacg acagctcctt gacggtcacc tactggcagc
    18121 agagcgcctc ggacgcactc ggttcatgag ccgccgcccg gcagggtctc ctggagccag
    18181 tcgaagacga cctcgcagtg cagctgcggg gccatggggg agcagtggag ctgggcgccc
    18241 tgggccgcgg tcagcttcag gtagtccttg ggcgaggtga gcgcgtcgta caactggcgc
    18301 ggctggccgg ggtagaactg ctcgtcctcg tagtccagga cgagggtggg cgccttgatc
    18361 cggctgacga cggaggcgat cgagagtgcc tggatacggg tggcgggggt gtagaagtcg
    18421 gtgaagagct tgccctgccg ggcctggagc atcgccggga tggagaaggg ctcgaagcgc
    18481 ttcttcagca cggcggcggc ctccggcggc agttcgggaa cgaccttcgt gttccagatg
    18541 tcgttcgtct cctccttgct gggggtgagg atctcccgga tctcgggcgg gaagcccagc
    18601 cagggctcga cgcagccggg catggccacc agcgcggcga tccggctctc gaaggccgcc
    18661 gccctcggcg cgaggtcacc cgccatgctc agaccggtca gggcgatcct gtcctggtcc
    18721 acgtccgggc gggcggacag ccagtcgacg agggggctga cgaccttctc ccaggtgggg
    18781 gtgaacacca cccggtcgac gaagagcagc tgcccctgcc ccggaccgtc gtagacgagc
    18841 gcgttccagc cgcgttcgag cgcggcgggg accccgtagg tccacatgtc gacgttctgg
    18901 ccgtcgctgc cgttggtcag gatcacggtg ggccggggcg tgttcgacgt gtcgggccgg
    18961 aagaaccaca ccggcaacgg cgtcgtgccg tacgggacgg cggccttgac cggggcgggc
    19021 tcgcacaggt cgcagaaggc gtcccaggcg tcccgtcccg ccttgtacag ctgctcctcg
    19081 ctgcccgggt ccttggaacc gaggacgaag aacagcgcct ggccgtagta ctgggcggcg
    19141 cgcagcgccc ggaaccgttt ggtctgggcg tcggccggtg agcccggcgg cggccccagg
    19201 agctggtcgc cgagcttgcg gaaggtctcg acgtacgtct gcgcggagag gccggccccg
    19261 ttgatcgcgt tcacggcggt gaggacctcg ccgacctcgg cggcgccggc gccggaggcc
    19321 ccgagcgcga ggaggccgtt gaagttgtac cccgggtcct tgaagagcgt catcgcaccg
    19381 ggggtggggc cggtcgcgga cgcgaggccg gagggagcgg agccgctggg ggtgggcgcc
    19441 ggggcgccgg gggtgcctcc gggagcgcag ccggcggcga gtgccgcccc ggcgccggcg
    19501 acgagcaggg cgcggcgggt gggaccggac tcccggtcgc ctgatatgta cgtcatatca
    19561 gtggaacgta gccctggtcc ggtacaccca cattccgacc tgctccgaac ggcttacggc
    19621 tcttacggcc tacggcttgt ggcttgccgt cggcggcggc ggtcagtagc ggggctcgtc
    19681 cggtgggcgg gggtggagcc ggtcgcgctc ccggccggag cggtccgcgt ccccggcggc
    19741 gcggatgtgg ctcaggtgcc accggctctg ctgggtcatc agcgagccga gcgggtgggc
    19801 cgcggtggcc gggttcgcca gacacagctc gtagcagcgg gccgccgggt cgggcgccgc
    19861 gaagtcggtc cggtatagct cggcgctgcg gaactgggcg tacgggtggc cgagttccgc
    19921 ggcggcggcg aacagctcca gggcgtgcgc cacgggagcc ccggtgagcg gcagcagccg
    19981 ttccaggtac atctcgccga gcgccagcat ggcctccggc tcgccgagcc gggcggcctc
    20041 gcggtaccag tgcgcggcgt ccgcgtagga ggcggtgatg ccggccggcg ggcagccgtc
    20101 gtaggagagc cggccgaggt agtgggcggc ccgccgggag gtgccggcgc tgccgcgcag
    20161 ccagggcgcc gccgcggcgt actcgccccg ggagaacagg acgtgcccga ggagttcggc
    20221 cgcctcggtg tgaccggcgc gggccgcggg ttcgaggaag aacgcggcgg cctcccggtg
    20281 ccgcggatcc tgccagcagt ggagcccgat ccggtggaac tcctccgccg tggtgggctc
    20341 ccgcccgtcc acggtgaagt cgacgccgtt ccacctcacc ccgtcccgcc cccgtccccg
    20401 cggcgcgcgc cgctccgtac ccgtggtccc cgccgccggt tcgcgggccc gaccccgttt
    20461 accgtacgcg gcagcggcca catgcggtcc atgaccgaac cggagaagag ggcccccgac
    20521 cggccttccg cgccggcgaa gcggcctcgt gcggtggccg cgcggctcga ctggacgggc
    20581 aggcgaacgt tttgtccggg accctcaggg taggcgccgt ttcgtccgca gtcatccagt
    20641 cgaacaatca agcaacaccg aggaatggag acgtcgtgtc cgtcgtcaag aacgccctcc
    20701 cggaagccga cctgaaggtc gtcggcgaag cgctccaggg cgctctggtg gacctggtgg
    20761 acctgggcct cgtcgccaag caggtccact ggaacgtggt cggcccccgc ttccggtccg
    20821 tgcacctcca gctggacgag gtcgtcacct cggcgcgcac ccactccgac gtggtcgccg
    20881 aacgcgcctc cgccctcggg atcaccccgg acggccgggc cgcgacggtg gcgtcgtcga
    20941 gcgcgatcag cggggtgccg gagggctggg tgaaggacgt ggacgcggta cgcatcctcg
    21001 tcgacggcct cagcgcggtg atcacccgca tgcgcgaacg catccatgcc accgcggacc
    21061 ccgacccggt cacccaggac atcctcatcg cggtgaccgg cgacctcgaa aagcaccact
    21121 ggatgttcgc cgccgagagc gcctgagcgg gcgccggggg tgggcgcggg cggctacggg
    21181 aggatggagt ccacgtagcc gccgtccact cgcagggcgc cgcccgtggt cgcggaggcg
    21241 aagggggagg acaggtagac caccatgtgg gcgatctcct ccggctcgat cagccgctgg
    21301 agcagcgact gggggcggtg cgtgcgcatg aacgcgcgtt gcgcctcgtc ccacggcagg
    21361 tcccggtcga ccagttcgta gacgaagtcc tcgacgccgc gggtgtgcgt cgggccggcg
    21421 atgacggagt tcacggtcac gcccgtgccc gcggcctcct tggcgaagcc ccgggacacg
    21481 gcgagcaggg ccgtcttgga catcccgtaa tggatcatct cggcggggac ggccaccgcc
    21541 gagtcgctgg cgatgttctg gacgcggccc caggagcgct ccatcatgcc cgggaggtac
    21601 cgccggatca tccggacggc ggtgagcacg ttcgtgtcga agtagcggcg ccattcgtcg
    21661 tcttcgatct ccagcgcctt cgccggtccg aagaccccga ggctgttgac gaggatgtcg
    21721 gtccggggga ccgcctcgaa gacggaccgc gcgccctcgt ccgtcgtgat gtcgccgggc
    21781 gccgcgacga actcgccgcc cgacgcgcgg aggcgggcca gcgcctcctc cacggatgcg
    21841 cggctgcggc cgttgacggc cacccgggcg cccgcggcgg ccaggccggc ggcgatggcc
    21901 gcgccgatcc cctgtgtgga gccggtgacc agggccgtcc tgccggagag gtcgatgagc
    21961 acgcgatacc cgcctcgtct gccgccgcgc ggcccgtcgg gtccgccgtc ctcgtcacgg
    22021 gttccccgta tcggcggatt cctcaccttc cgcccgggag acggccctca ccgcggctgc
    22081 ccttgccggg cccggctccg tcactatggg ggcgtgcacc gcttccgctt cccgcgctac
    22141 ctgctcatat gggtgtcctg tacggccgcc agcgtgaccg ccgtcatggc caccgtcgac
    22201 ttcgtggcgg gctcgacacg gccgaaaccg ccggtcgcgc ggtcggcgcc gaccgtgttc
    22261 ctctcaccca gtgcctcggc ttctccttcg gcttccgttt ccggttccgg ctcgccctcc
    22321 gcttccgcga gcccttccgc gtcgccctcg gcctccagcc cgcaggtctc cactcccgcg
    22381 gccgcctccc gcccgccttc gcgggcgccc ggccccctcc cctcaccggc cggcacaccc
    22441 cgtaccaccc cggtccaggg ctgcgggggc ggcggggcag ggtcgcacac cgtcccgtcg
    22501 acgggcggca aggcgaccgt gcggtacggg agcgacaagg tgtgcctgat ctccgcggtc
    22561 ccggcgctcg ggttcaaggt gagcaccgcc cagaacgcgg accacacgct caccgtcacg
    22621 ttcaccggca gcggtca
//
