LOCUS       NZ_BMVE01000002        33535 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces goshikiensis strain JCM 4640 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVE01000002
VERSION     NZ_BMVE01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1126124)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650555.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:30:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,491
            CDSs (total)                      :: 7,410
            Genes (coding)                    :: 7,286
            CDSs (with protein)               :: 7,286
            Genes (RNA)                       :: 81
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 44 of 125
            Pseudo Genes (incomplete)         :: 101 of 125
            Pseudo Genes (internal stop)      :: 9 of 125
            Pseudo Genes (multiple problems)  :: 27 of 125
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1092589
            Orig. end                         :: 1126124
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVE01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..33535
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="7"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..33535
                     /SMILES="C([*])C(-O)C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33535
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:31655](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..31655
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(2..1213)
                     /locus_tag="IE248_RS10030"
                     /old_locus_tag="GCM10010336_20410"
     CDS             complement(2..1213)
                     /NRPS_PKS="Domain: Aminotran_1_2 (53-334). E-value:
                     6.2e-09. Score: 27.3. Matches aSDomain:
                     nrpspksdomains_IE248_RS10030_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741985.1"
                     /locus_tag="IE248_RS10030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20410"
                     /product="dTDP-4-dehydro-6-deoxyglucose aminotransferase"
                     /protein_id="WP_190030439.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.9e-107,
                     bitscore: 355.4, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.5e-08, bitscore:
                     27.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNVGDLAVFGGPSAFLQPLHVGRPNVGDRARFFDRVNWALDHQ
                     WLTNGGPLAREFEQRVAELAGVRYCVSTCNATVALQLLARAADLSGEVIMPSLTFPATA
                     QAFRWLGLTPVFCDIDPATSCLDPALVEAAITPRTSAIVPVHLWGRPCAVDQLAKVAAD
                     HGIKLFYDAAHGLGCTAEGQPIGGFGQAEVFSFHATKVVNAFEGGAVVTDDEELAQRVR
                     AMHNFGFAQGRVSTETGTNGKMTEAAAAMGLTSLDAFEETVRRNEANYDDYRSELAGIA
                     GLNVMEFNRAERNNYHYLIVEVDAAVTGVHRDLLDWVLRAENVVCQRYFSPGCHEMELY
                     RSERPVTLPHTERLAQRVLALPTGPTVSREDIRRVCDIVRVTLERGHEVTRRADERVPS
                     TLAP"
     aSDomain        complement(212..1054)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10030_Aminotran_1_2.1"
                     /evalue="6.20E-09"
                     /label="IE248_RS10030_Aminotran_1_2.1"
                     /locus_tag="IE248_RS10030"
                     /protein_end="334"
                     /protein_start="53"
                     /score="27.3"
                     /tool="antismash"
                     /translation="AREFEQRVAELAGVRYCVSTCNATVALQLLARAADLSGEVIMPSL
                     TFPATAQAFRWLGLTPVFCDIDPATSCLDPALVEAAITPRTSAIVPVHLWGRPCAVDQL
                     AKVAADHGIKLFYDAAHGLGCTAEGQPIGGFGQAEVFSFHATKVVNAFEGGAVVTDDEE
                     LAQRVRAMHNFGFAQGRVSTETGTNGKMTEAAAAMGLTSLDAFEETVRRNEANYDDYRS
                     ELAGIAGLNVMEFNRAERNNYHYLIVEVDAAVTGVHRDLLDWVLRAENVVCQRYFSPGC
                     "
     misc_feature    complement(1199..1214)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.74"
                     /tool="antismash"
     gene            complement(1353..2192)
                     /locus_tag="IE248_RS10035"
                     /old_locus_tag="GCM10010336_20420"
     CDS             complement(1353..2192)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741995.1"
                     /locus_tag="IE248_RS10035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20420"
                     /product="TylF/MycF family methyltransferase"
                     /protein_id="WP_229895212.1"
                     /transl_table=11
                     /translation="MIIQLGDIVTVQTHELYVDLIKRVVTNTIYGDHPTFPVGMNVLDK
                     DLADSMRPDAPGSAVDHGRFDAGHRAEGLDVPTVAHTMIGLHRLDNIQKCVEQVLRDGV
                     PGDFIETGVWRGGACILMRALLKAHGVEDRNVWLADSFAGVPVTSEDSHPLDQAMEFHN
                     LNWVLSCSEEQVRQNVARYGLLDDQVKFLPGMFADTLPNAPIDQLAVLRLDGDLYESTM
                     DALVNLYPKVSVGGFVIVDDYLIPACKQAVHDYRNEHGIDEPIETVDVTGVYWRRAH"
     misc_feature    complement(2272..2285)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.23"
                     /tool="antismash"
     misc_feature    2299..2313
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            complement(2330..3787)
                     /gene="desII"
                     /locus_tag="IE248_RS10040"
                     /old_locus_tag="GCM10010336_20430"
     CDS             complement(2330..3787)
                     /EC_number="4.3.1.30"
                     /GO_function="GO:0016841 - ammonia-lyase activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0033068 - macrolide biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="desII"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741987.1"
                     /locus_tag="IE248_RS10040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20430"
                     /product="dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase"
                     /protein_id="WP_190030440.1"
                     /transl_table=11
                     /translation="MTSQASTPADPVATCARPGADLAAAVQTVRRALTADGHVGADEAP
                     AVARRLVQLAEHYGNHPFTPLEDVRRLLDVDRASFSRLLGFFGLVPQLRHAVETGPAGK
                     YWQNTLLPLEQRGVFDAVLAHKPVFPYIVGLYPGPSCMFRCHFCVRVTGARYDPSALES
                     GNALFESVIDEIPAGNPYAMYFSGGLEPLTNPGLGALSSRAAARGLRPTVYTNSFALTE
                     RTLARQPGVWDLHAVRTSLYGLNDEEYEETTGKRASFGRVRANLQRFQQLRTERESPIR
                     VGLSYIVLPGRVHRLLDLVGFIAELNEAAPDRPVDFLNVREDYSGRGDGRLSEAERTEL
                     HEGLLAFEEQVSRRTPTLNVDYGYALHSLRTGADAELLRIRPGTMRPSVHPQVSVQVDL
                     LGDVYLYREAGFPDLDGADRYIAGRVGPGTSLAEVVERFVNDDRRIAPHDGDEYFMDGF
                     DQVVTARLNQLEADVAAGWGDTRGFLR"
     gene            complement(3873..6344)
                     /locus_tag="IE248_RS10045"
                     /old_locus_tag="GCM10010336_20440"
     CDS             complement(3873..6344)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741988.1"
                     /locus_tag="IE248_RS10045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20440"
                     /product="beta-glucosidase"
                     /protein_id="WP_190030441.1"
                     /transl_table=11
                     /translation="MLFGTRRTGRQTRRAVGYALAALCVGGLLTAPSATGAPAAGPGTP
                     RVRSLVAKMTLDEKISFVHWTTGPVGGPTMTGIGYLPGVQRLGIPELRTADGPVGIRLL
                     GGTATAMPTPVALASTFDEHLAEEYGTVLGREGRALGQDIVLGPMTNIIRVPHAGRNFE
                     TYSEDPLLSSRMAADEVRGIQDQGLMATVKHFAANNQEYQRETIDATVDEQTLQEVELP
                     AFRSAVKAGAASVMCSYNSVNGTHACSNEHLLQDVLREQWDFRGWVLSDWLATHATSDI
                     TKGLDQELGVELALGQPVPDSKYFSSALKTAIEDGSIPEATLDRSVIRILGQMERFGLL
                     DGKATERPQRDPEAGRKTARTIAENGGVLLRNEQRTLPLAGGKAADIAVIGNSAKHPKV
                     TGNGSAHVIPDRATAPVDAIERRAGDKATVVYEPGEDLVGVPVPDSSLAPAFKGGKQLQ
                     PGGQGVFYKGQLTVPADGDYKIAFSAVGGVANLQIAGQSAVLGTEAFGTVTTTMHLTRG
                     THEVTMNGWAFEKTPLSVELSWVTPEAARTDFDRAVAAAAKARTAIVFAQDDSAEGVDR
                     TSLSLPGRQDELIAAVTKVNPRTIVVLNTGSSVLMPWLRDTAAVLEMWYPGQEGAEATA
                     ALLFGDADPSGRLTQTFPATETGHPMAGDPHRYPGVDGKETYSEGLDVGYRWYDRTGVA
                     PLFPFGYGLSYTTFAYSDLSVVRTPRGLDATVTVRNTGDRAGRETVQVYLGASPDTQAP
                     QALRKLAGFGKVTLEPGEQRRVTVPVDEEQLRYWDTSAGSWRLGTGRRTVYVGPSAAKT
                     SLTTPVTVLPR"
     gene            complement(6506..7699)
                     /locus_tag="IE248_RS10050"
                     /old_locus_tag="GCM10010336_20450"
     CDS             complement(6506..7699)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606596.1"
                     /locus_tag="IE248_RS10050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20450"
                     /product="cytochrome P450"
                     /protein_id="WP_190030442.1"
                     /sec_met_domain="p450 (E-value: 1.6e-13, bitscore: 46.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTKSAPVSYPFSRSTGLDLDEAYEQAQKSAGLLWVHMPYGEPS
                     WLVCRYDDARFVLGDRRFSHAAEAENDAPRMRELRTPNGILGMDAPDHTRLRGLVTRAF
                     TPRRVEAMRPRVRKMTESLLQDMTALGAPADLVEHYAVPIPVAVICGLLGVPEEDRALF
                     RGWCDIAMSTSSLTAEDHVRLAGELTGYLADLIADRRAAPQDDLVSALVEARDAEGRLS
                     QEELVNLIVFLLFAGHETTASQISNFVLLLLEQPDQLALLRDRPDLLDNAVEELTRFVP
                     LGSQAGFPRYATEDVEVGGTLVRAGEPVLVQMNAANRDALRFRSPGVLDITRDDARQHL
                     GYGHGPHHCLGASLARLELQEALRTLLDGLPGLHLAQAVEWKTQMVVRGPRTMLVAW"
     gene            complement(7777..9000)
                     /locus_tag="IE248_RS10055"
                     /old_locus_tag="GCM10010336_20460"
     CDS             complement(7777..9000)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741990.1"
                     /locus_tag="IE248_RS10055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20460"
                     /product="cytochrome P450"
                     /protein_id="WP_190030443.1"
                     /sec_met_domain="p450 (E-value: 1e-21, bitscore: 73.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSCPVHQTRPYPFSLPEGIALDPLYSHLREHEPVSRIRMPYGG
                     EAWLLTRHADVKAVLGDPRFSMEAGAGRDVPRPTEYPLPAGGLISMDPPGHTRLRRLAG
                     KAFTARRVEELRPQVSRFTHELLDGMVARDEPSGEIMEDLALPVSISVICRLLGVSYDD
                     RHLFRNFSEALVSSSLGPAELQRVTEGFTAYMAELVADRRARPTDDFLSTMVQARDEDD
                     RLSEAELLMLGAGLLISGYETTATQIGNFVHLLLDDRRLYERLVADPDLVPAAVEELLR
                     FTPLSTTDGFARIALEDVEIGGTLIRAGEAVITSIASANLDDTAFPGAASLDFTRAQNP
                     HLGFGHGAHYCMGAPLARLELQVVLSTLVERLPGLRLSVPASELRWRTGSLMRTPEAVP
                     VTWGYPAE"
     gene            complement(9015..9839)
                     /locus_tag="IE248_RS10060"
                     /old_locus_tag="GCM10010336_20470"
     CDS             complement(9015..9839)
                     /NRPS_PKS="Domain: Thioesterase (31-255). E-value: 1.3e-57.
                     Score: 187.8. Matches aSDomain:
                     nrpspksdomains_IE248_RS10060_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139666.1"
                     /locus_tag="IE248_RS10060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20470"
                     /product="thioesterase II family protein"
                     /protein_id="WP_190030444.1"
                     /sec_met_domain="Thioesterase (E-value: 6.6e-54, bitscore:
                     179.3, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-12, bitscore:
                     44.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGSAATAPGSTDAGDLWLRRYQPVADPALRLVCLPHAGGSASA
                     FLPFTHLLPDWVEVLAVQYPGRQDRRLEPFVDTVDSLVTQIAGALGPWLDRPVALFGHS
                     LGSLVAFETARRLAEQAPESRVAHLFVSGRVAPTIAHRTTAHLLSDDRLVAKLAELQGT
                     DPRVLADQEVLRLALPAIRNDYRAAATYTWRPGAPLSCPITVLTGSADPHVPTDGALAW
                     HRLTTGETAFRSFPGGHFYLTEHAEAVCRTIRTATGLAMRAPAPLKSSRRPV"
     aSDomain        complement(9075..9746)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10060_Thioesterase.1"
                     /evalue="1.30E-57"
                     /label="IE248_RS10060_Thioesterase.1"
                     /locus_tag="IE248_RS10060"
                     /protein_end="255"
                     /protein_start="31"
                     /score="187.8"
                     /tool="antismash"
                     /translation="RLVCLPHAGGSASAFLPFTHLLPDWVEVLAVQYPGRQDRRLEPFV
                     DTVDSLVTQIAGALGPWLDRPVALFGHSLGSLVAFETARRLAEQAPESRVAHLFVSGRV
                     APTIAHRTTAHLLSDDRLVAKLAELQGTDPRVLADQEVLRLALPAIRNDYRAAATYTWR
                     PGAPLSCPITVLTGSADPHVPTDGALAWHRLTTGETAFRSFPGGHFYLTEHAEAVCRTI
                     RT"
     CDS_motif       complement(9489..9554)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10060_0001"
                     /evalue="1.50E-08"
                     /label="NRPS-te1"
                     /locus_tag="IE248_RS10060"
                     /protein_end="117"
                     /protein_start="95"
                     /score="27.1"
                     /tool="antismash"
                     /translation="RPVALFGHSLGSLVAFETARRL"
     gene            complement(9860..10831)
                     /gene="rfbB"
                     /locus_tag="IE248_RS10065"
                     /old_locus_tag="GCM10010336_20480"
     CDS             complement(9860..10831)
                     /EC_number="4.2.1.46"
                     /GO_function="GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (4-212). E-value: 1.6e-19.
                     Score: 62.0. Matches aSDomain:
                     nrpspksdomains_IE248_RS10065_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rfbB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741992.1"
                     /locus_tag="IE248_RS10065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20480"
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="WP_190030445.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.7e-21, bitscore:
                     71.3, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.7e-22,
                     bitscore: 75.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.4e-18, bitscore:
                     62.0, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLVTGAAGFIGSHFVRQLLSGSYPELADAHVLSLDKLTYAGNT
                     ENLAEVAGHPRHTFLHGDICDRPTVTQALRGIDLVVHFAAESHVDRSITDSAAFITTNV
                     LGTHTLLRSALEAGVSRFVHVSTDEVYGSVPEGSSAETDPLDPNSPYAASKASSDLLAL
                     AFHRTHGLDVRVTRCSNNYGPHQHPEKVVPLFVTHLLEGLHLPLYGDGLHRRDWLHVDD
                     HCRGIAMVAGRGRAGEVYNIGGGTELSNVDLTRRLLGVFGADWSVVDRVPDRAAHDRRY
                     CVDTRKITEELGWAPRVAFERGLAETVDWYRDNGTWWKALKP"
     aSDomain        complement(10196..10819)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10065_NAD_binding_4.1"
                     /evalue="1.60E-19"
                     /label="IE248_RS10065_NAD_binding_4.1"
                     /locus_tag="IE248_RS10065"
                     /protein_end="212"
                     /protein_start="4"
                     /score="62.0"
                     /tool="antismash"
                     /translation="VTGAAGFIGSHFVRQLLSGSYPELADAHVLSLDKLTYAGNTENLA
                     EVAGHPRHTFLHGDICDRPTVTQALRGIDLVVHFAAESHVDRSITDSAAFITTNVLGTH
                     TLLRSALEAGVSRFVHVSTDEVYGSVPEGSSAETDPLDPNSPYAASKASSDLLALAFHR
                     THGLDVRVTRCSNNYGPHQHPEKVVPLFVTHLLEGLHLPLYGDGL"
     gene            complement(10874..11761)
                     /gene="rfbA"
                     /locus_tag="IE248_RS10070"
                     /old_locus_tag="GCM10010336_20490"
     CDS             complement(10874..11761)
                     /EC_number="2.7.7.24"
                     /GO_function="GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="rfbA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009072176.1"
                     /locus_tag="IE248_RS10070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20490"
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="WP_063781072.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-10, bitscore:
                     37.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGIILAGGSATRLQPLTGALSKQQLPVYDKPMIYYPLSVLMLAG
                     IQDILIISSHQHVETFQVMLGDGSRLGIHLDYAVQDEPRGVADAFLVGDKHIGNDRVAL
                     ILGDNVFHGPGFSTVLKHSLQRLDGCELFGYPSKSPDRYGVAEIDEQGNLLSLEEKPSR
                     PRSNLAVTGLYFYDNDVVELAKDLKPSTRNELEITDINLSYLEQGRARLTQLGRGFAWL
                     DMGTHDSLLQAGQYVQLLEQRQGVRIACVEEIALRMGFIDADTCYRLGEELSASSYGGY
                     LMEVASGLGATLTG"
     gene            complement(12101..12691)
                     /gene="gerF"
                     /locus_tag="IE248_RS10075"
                     /old_locus_tag="GCM10010336_20500"
     CDS             complement(12101..12691)
                     /EC_number="5.1.3.27"
                     /codon_start=1
                     /gene="gerF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_209522025.1"
                     /locus_tag="IE248_RS10075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20500"
                     /product="dTDP-4-dehydro-6-deoxyglucose 3-epimerase GerF"
                     /protein_id="WP_190030446.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 2.8e-52,
                     bitscore: 172.6, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPLSIEGAWSQEPVIHSDHRGRSHEWFRGERFRKTFGHDFPVAQ
                     VNVAVSHRGALRGIHYTEIPPGQAKYSVCVRGAGLDVIVDVRIGSPTFGRWEIVPMDAE
                     RNTAVYLTAGLGRAFLSLTDDATLVYLCSSGYAPEREHSVNPLDPDLGIVWPADIEPLL
                     SDRDKNAPTLATAERLGLLPTYQAWQEQQKAEA"
     gene            complement(12757..13524)
                     /locus_tag="IE248_RS10080"
                     /old_locus_tag="GCM10010336_20510"
     CDS             complement(12757..13524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741995.1"
                     /locus_tag="IE248_RS10080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20510"
                     /product="TylF/MycF family methyltransferase"
                     /protein_id="WP_073796601.1"
                     /transl_table=11
                     /translation="MTVIPADADLYLDLLKKVVTNMIYEDQTNVAGLITSSSYSAELRA
                     VGEDFPHVAHTMVGLKRLDNLQKCLEDVLRDGVPGDFAETGVWRGGACIFARGVFQAHG
                     VRDRKVWVADSFQGFPKTTEDDHQLDVDIDLGQYNEVLSIPVDVETVKRNFARYGLLDD
                     QVRFLPGWFKDTMPTAPIEKLAVLRLDGDSYAATREVLTSLYHKVSVGGYVIVDDYCIP
                     ACRQAVHEFRDEHGITDEIHQIDRQGSYWRRSS"
     misc_feature    13513..13528
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.6"
                     /tool="antismash"
     misc_feature    13515..13529
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            14016..15047
                     /locus_tag="IE248_RS10085"
                     /old_locus_tag="GCM10010336_20520"
     CDS             14016..15047
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016712 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, reduced flavin or flavoprotein as one
                     donor, and incorporation of one atom of oxygen [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020550821.1"
                     /locus_tag="IE248_RS10085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20520"
                     /product="cytochrome P450"
                     /protein_id="WP_229895213.1"
                     /sec_met_domain="p450 (E-value: 1.4e-28, bitscore: 95.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALLADPRITIDPAKLPKLSASDGDGGGFRSLLTMDPPDHSVLR
                     RMLIPEFSVRRVREMRPGVERTVHRLLDRILEQRGPVDLVAELALPMSTLVICQLLGVP
                     YEDHEFFQERSEQATRVGGNEESLAALLELRDYLDRLVTAKIETPGDDLLCRLIADRLH
                     TGEMRHAEIVDNAVLLLAAGHETSASMVALSVLTLLQHPDASTQLRGDSTLLPQAVDEL
                     LRFHSIADGLRRAVTEDIELGGITLRAGDGLILSLASANRDESAFASPDDFDLHGSARQ
                     HVAFGYGPHQCLGQNLARLELEVTLGAVVERIPTLRLAGEVDALRVKRDSTIFGLHELP
                     VEW"
     misc_feature    15051..15069
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.15"
                     /tool="antismash"
     gene            15071..15286
                     /locus_tag="IE248_RS10090"
                     /old_locus_tag="GCM10010336_20530"
     CDS             15071..15286
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024851.5"
                     /locus_tag="IE248_RS10090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20530"
                     /product="ferredoxin"
                     /protein_id="WP_229895214.1"
                     /transl_table=11
                     /translation="MTVEQSRCLGAGQCEQLVPEVFRQDEEGLSRVLVAEPEPALWPRV
                     LQTVQLCPVQAVIVQEAPGRAPQDTE"
     gene            15283..16263
                     /locus_tag="IE248_RS10095"
                     /old_locus_tag="GCM10010336_20540"
     CDS             15283..16263
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (12-215). E-value:
                     1.1e-15. Score: 49.4. Matches aSDomain:
                     nrpspksdomains_IE248_RS10095_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741998.1"
                     /locus_tag="IE248_RS10095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20540"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190030449.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.4e-14, bitscore:
                     49.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.4e-07,
                     bitscore: 26.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.6e-14, bitscore:
                     49.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADRWAGRTVLVTGALGFIGSHFVRQLDARGAEVLALYRTERPE
                     IQAEFAALNRVRLVRTELRDESDVRGAFKYLAPSIDTVVHCAAMDGNAQFKLERSAEIL
                     DSNQRTISNLLNCVRDFGVGEVVVMSSSELYSASPTVAAREEDDFRRSMRYTDNGYVLS
                     KTYGEILARLHREQFGTNVFLVRPGNVYGPGDGFDRSRGRVIPSMLAKADAGEEIEIWG
                     DGSQTRSFVHVADLVRASLRLLETGKYPEMNVAGAEQVSILELARMVMAVLGRPERIRL
                     DPSRPVGAPSRLLDLSRMSEVIDFDPQPLRAGLEETARWYRLHKR"
     CDS_motif       15310..15396
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10095_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE248_RS10095"
                     /protein_end="38"
                     /protein_start="9"
                     /score="14.1"
                     /tool="antismash"
                     /translation="TVLVTGALGFIGSHFVRQLDARGAEVLAL"
     aSDomain        15319..15927
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10095_NAD_binding_4.1"
                     /evalue="1.10E-15"
                     /label="IE248_RS10095_NAD_binding_4.1"
                     /locus_tag="IE248_RS10095"
                     /protein_end="215"
                     /protein_start="12"
                     /score="49.4"
                     /tool="antismash"
                     /translation="VTGALGFIGSHFVRQLDARGAEVLALYRTERPEIQAEFAALNRVR
                     LVRTELRDESDVRGAFKYLAPSIDTVVHCAAMDGNAQFKLERSAEILDSNQRTISNLLN
                     CVRDFGVGEVVVMSSSELYSASPTVAAREEDDFRRSMRYTDNGYVLSKTYGEILARLHR
                     EQFGTNVFLVRPGNVYGPGDGFDRSRGRVIPSMLAKADAG"
     misc_feature    15454..15456
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16275..16290
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            16295..17506
                     /locus_tag="IE248_RS10100"
                     /old_locus_tag="GCM10010336_20550"
     CDS             16295..17506
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037650.5"
                     /locus_tag="IE248_RS10100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20550"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_190030450.1"
                     /transl_table=11
                     /translation="MVKHAPNSLIREIIRAAGGHDADLKDLAARYAPADIVRVLLDEIT
                     TRCPAPVNDVPVLVELAVRAGDQLFPTYLYVLKGGPVRLATKDEAFVAMRVEYELGELA
                     RELFGPVRENVTGVRRTTLFPYVTDAQSEGEEDSGAEHIGTHFLAAQQGSQTVLAGCHS
                     HKPDLSELSSRYLTPKWGSLHWFTPHYDRHFSSYRDQQVRVLEIGIGGYKHPEWGGGSL
                     RMWKHFFHRGEIYGLDIVDKSHFDAPRITTLRGDQSDPDYLRSIAEEYGPFDIVIDDGS
                     HINDHIRTSFQALFPHVRPGGLYVIEDLWTAYWSGFGGNEDPKQYSGTSLGLLKSLVDS
                     IQHEELPQAGGHRPGYVDQHVVGMHLYHNLAFIEKGTNAEGGIPPWIPRDFETLVAVSS
                     GGHE"
     gene            17562..18818
                     /locus_tag="IE248_RS10105"
                     /old_locus_tag="GCM10010336_20560"
     CDS             17562..18818
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102: glycosyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF018434.5"
                     /locus_tag="IE248_RS10105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20560"
                     /product="glycosyltransferase"
                     /protein_id="WP_190030451.1"
                     /sec_met_domain="MGT (E-value: 8.1e-37, bitscore: 123.2,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVTLLSVGSRGDVQPFVALGIGLKARGHDVTLAAPATLRPLVER
                     AGLTYKLSPGDPDGFFRMPEVIEALQRSPSFKNMLAGMPEAPESYTQQVVDAIHDAAEG
                     ADLIVNAPLTLAAAYGHPPAPWASVSWWPNSMTSAFPAVESGQRRFGPLTPLYNRYTHR
                     RAARDEWEWRRPEVDGYRKRLGLRPFGDESPFLRLGHDRPYLFPFSPSVLPKPRDWPRQ
                     SHVTGYWFWDQHWEPPAELEAFLADGEPPVALTFGSTWSLHRQEEALQAALDAVRGVGR
                     RLVMVDGPDGDLPDDVLRLHQVDYATLFPRMAAVIHHGGAGTTAEVVRAGVPQVIVPVF
                     ADHPFWAARLSRAGVAARPVPFTRFSREALAQSVRQAVTDPAMAARARRLGELVSKERG
                     VDTACDILEKWAETARVAP"
     gene            complement(18889..19731)
                     /locus_tag="IE248_RS10110"
                     /old_locus_tag="GCM10010336_20570"
     CDS             complement(18889..19731)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742001.1"
                     /locus_tag="IE248_RS10110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20570"
                     /product="putative RNA methyltransferase"
                     /protein_id="WP_190030452.1"
                     /transl_table=11
                     /translation="MLNRIVRYLACPHCGASLALGDRALSCPAGHSFDIAKQGYVNLLP
                     GATKLRADTKEMVEARDAFLSAGHYGPVMDALVDLARRTADPAVPGCIVDIGGGTGHYH
                     AKVVDAFPDVDGLLLDISKYAVRRAAKAHPRIAAAVTDAWQTLPLQDASAAVVINTFAP
                     RNGPELHRILHHRGVLLVVTPLPDHLQELIGTLGLLQVDEGKESRLAEQLAPHFSAVAT
                     ERLTRTMALDHQALAHLVGMGPNAWHRDVQRDHEMIQRLPVPSQVTLSVRLSAYRLSA"
     gene            20001..25637
                     /locus_tag="IE248_RS10115"
                     /old_locus_tag="GCM10010336_20580"
     CDS             20001..25637
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (12-421). E-value:
                     3.5e-160. Score: 525.5. Matches aSDomain:
                     nrpspksdomains_IE248_RS10115_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (524-820). E-value: 6.9e-98.
                     Score: 319.6. Matches aSDomain:
                     nrpspksdomains_IE248_RS10115_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (891-1058). E-value: 4.2e-50.
                     Score: 162.3. Matches aSDomain:
                     nrpspksdomains_IE248_RS10115_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1405-1584). E-value: 2e-59.
                     Score: 192.5. Matches aSDomain:
                     nrpspksdomains_IE248_RS10115_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1697-1782). E-value: 9.9e-28.
                     Score: 88.3. Matches aSDomain:
                     nrpspksdomains_IE248_RS10115_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1795-1878). E-value:
                     3.3e-07. Score: 23.0. Matches aSDomain:
                     nrpspksdomains_IE248_RS10115_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.5"
                     /locus_tag="IE248_RS10115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20580"
                     /product="type I polyketide synthase"
                     /protein_id="WP_190030453.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.4e-73, bitscore:
                     242.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 5.3e-159, bitscore:
                     525.5, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-96, bitscore: 319.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.7e-58, bitscore:
                     193.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-11, bitscore:
                     40.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPKNGAQRSSDIAVVGMSCRLPGAPGIDEFWELLTSGGSAIERR
                     ADGTWRGSLEGAAEFDAAFFGMSPRQAAAADPQQRLMLELGWTALEDAGIVPGSLAGTD
                     TGVFVGIAADDYAALLHRSETPVSGHTATGLSRGMAANRLSYLLGLRGPSLAVDSAQSS
                     SLVAVHLACESLRRGESDLAIVGGVSLILAENSTAGMELMGALSPDGRCYTFDARANGY
                     VRGEGGACVVLKPLDRALADGDRVHCVIRGSAVNNDGGGSTLTTPHREAQEAVLRAAYE
                     RSGVGPDQVSYVELHGTGTPVGDPIEAAALGAVLGTARGRSTPLSVGSAKTNVGHLEAA
                     AGLVGFVKAALCVREGVVPPSLNHATPNPAIPMDRLNLRVPTRLDTWPQPDEQATGRLR
                     LAGVSSFGMGGTNAHVVVEEAPVPEEGEFVGDAPLAVVPVVVSGRSAGVVAELASRMGE
                     VAGSGRLVDVGLSSVVSRSVFEHRSVVLAEDSVDLSAGLDAVAAGDGLSPGVVSGVVSV
                     EGARSVFVFPGAGAKWSGMAARLWAESVVFAESMARCEAAFEGLVDWRLSDVIAQVPGA
                     VSLEREDVAQPASFAVMVSLAALWRSLGVVPDAVVGHSQGEIAAAVVAGGLSLEDGARA
                     VVFRSRVAEEVLSGGGIASVRLSRAEVEERLAGGGGGLSVAVVNAPSSTVVAGELGELE
                     RFVAACEAEGVRARRLEFGYASHSVFVEPARGRLLEALADVRPVSGEIPFYSTVEAGVV
                     DTASLDAEYWFGNLRRPVRFQETVEQLLADGFRVFVECGAHPVLTGAVQETAESVGRQV
                     CAVGSLRREDGGLRRFLTSVAEAFVQGVDVTWPALFADTGARTVDLPTYPFQRQHYWAQ
                     ASPAGTGSSAAARFGMTWEEHPLLSGALPLAESGELLLVGRISPASHSWIADHTVAGTA
                     LLPGTAFVGMALHAAAVVGCAGVEELSIEAPLPVHGGIRLQVVIDEPDSSDRRRVSVFA
                     RPEAEDGDTGRWTRHATGVLTPAAAPDPGRPQWSREAWPPSGSVRAEAAELYDRFSALG
                     YEYGEVFAGVEAVWLREGEVFAEVRLPAGAAPDAERFGVHPGLLDAALQPWLLGDFLSR
                     PDDGSVLLPFAWRGITLHATGADALRVRLGPAGEGAMSLEAVDLAGAPVLSMDALVLRP
                     LAQDRLVELVGGTTSAPLYRVDWQRSPIANTAPSATGLFGSFPSGATRRWAVVGQGGAA
                     ARYATADPGTGCVGVFPDLDALRTALDSGADRPDIVLADFGARPGTAAPHGTALADGVR
                     DTARRGLALVQGWLSDERFAAARLAVLTEHAVATEADERQVDLAGSALWGLMRSAQTEH
                     PDRFVLVEHDGQDASYQALPAALDSGIPQLALRSGKVRTPGLAVLPTPGDGPTATGTGF
                     DPEGTVLVTGATGTLGSLLARHLVTAHGVRHLLLLSRSGRDAGRAAELERELTGLGAEF
                     QLLSCDATDRVALREALATVPAAHPLTAVIHTAGVLDDGVVEALTPERLDRVLRPKTDA
                     ALNLHELTAGMPLKAFVLYSGAVGLLGGAGQANYAAANAFLDGLAQYRHAQGLPAVSLA
                     WGLWSAASTFTGHLGEVDLRRMERSGIAPLTNEQGLELLDRALGAAAGADAPQICAMRL
                     DTAALRRQASEHGPASVPLLLRTLAAPAVRIGAARTGRGARAASAVTDVPSRAQDLRER
                     LAGLDAAGRRDELLAVAQAQLADVLGFTDKTAVDPVRSFREIGLDSLTAVELRNRLDAV
                     TGLRLSSALVFDHPNLDALAGHLAELLMAEGKDDAGAAALSGVDALDRAVRGMAADDTR
                     RDAVRRRLTELLAVVGDAPRDGDRSTRTAAGTGSHGVQAGPDLLGQLDSASDDDLFAFI
                     EDQL"
     aSDomain        20037..21263
                     /ASF="found active site cysteine: False, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10115_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="3.50E-160"
                     /label="IE248_RS10115_PKS_KS.1"
                     /locus_tag="IE248_RS10115"
                     /protein_end="421"
                     /protein_start="12"
                     /score="525.5"
                     /tool="antismash"
                     /translation="IAVVGMSCRLPGAPGIDEFWELLTSGGSAIERRADGTWRGSLEGA
                     AEFDAAFFGMSPRQAAAADPQQRLMLELGWTALEDAGIVPGSLAGTDTGVFVGIAADDY
                     AALLHRSETPVSGHTATGLSRGMAANRLSYLLGLRGPSLAVDSAQSSSLVAVHLACESL
                     RRGESDLAIVGGVSLILAENSTAGMELMGALSPDGRCYTFDARANGYVRGEGGACVVLK
                     PLDRALADGDRVHCVIRGSAVNNDGGGSTLTTPHREAQEAVLRAAYERSGVGPDQVSYV
                     ELHGTGTPVGDPIEAAALGAVLGTARGRSTPLSVGSAKTNVGHLEAAAGLVGFVKAALC
                     VREGVVPPSLNHATPNPAIPMDRLNLRVPTRLDTWPQPDEQATGRLRLAGVSSFGMGGT
                     NAHVVVEEAP"
     aSModule        20037..25346
                     /complete
                     /domains="nrpspksdomains_IE248_RS10115_PKS_KS.1"
                     /domains="nrpspksdomains_IE248_RS10115_PKS_AT.1"
                     /domains="nrpspksdomains_IE248_RS10115_PKS_DH.1"
                     /domains="nrpspksdomains_IE248_RS10115_PKS_KR.1"
                     /domains="nrpspksdomains_IE248_RS10115_PKS_PP.1"
                     /locus_tags="IE248_RS10115"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20133..20156
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0001"
                     /evalue="2.20E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE248_RS10115"
                     /protein_end="52"
                     /protein_start="44"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="RADGTWRG"
     CDS_motif       20454..20501
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0002"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE248_RS10115"
                     /protein_end="167"
                     /protein_start="151"
                     /score="11.5"
                     /tool="antismash"
                     /translation="GPSLAVDSAQSSSLVA"
     CDS_motif       20643..20681
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0003"
                     /evalue="6.20E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE248_RS10115"
                     /protein_end="227"
                     /protein_start="214"
                     /score="15.8"
                     /tool="antismash"
                     /translation="FDARANGYVRGEG"
     CDS_motif       20874..20921
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0004"
                     /evalue="4.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE248_RS10115"
                     /protein_end="307"
                     /protein_start="291"
                     /score="12.6"
                     /tool="antismash"
                     /translation="YVELHGTGTPVGDPIE"
     CDS_motif       20982..21026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0005"
                     /evalue="2.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE248_RS10115"
                     /protein_end="342"
                     /protein_start="327"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GSAKTNVGHLEAAAG"
     CDS_motif       21567..21620
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0006"
                     /evalue="4.90E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE248_RS10115"
                     /protein_end="540"
                     /protein_start="522"
                     /score="18.9"
                     /tool="antismash"
                     /translation="VFVFPGAGAKWSGMAARL"
     aSDomain        21573..22460
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10115_PKS_AT.1"
                     /evalue="6.90E-98"
                     /label="IE248_RS10115_PKS_AT.1"
                     /locus_tag="IE248_RS10115"
                     /protein_end="820"
                     /protein_start="524"
                     /score="319.6"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGAGAKWSGMAARLWAESVVFAESMARCEAAFEGLVDWRLSDV
                     IAQVPGAVSLEREDVAQPASFAVMVSLAALWRSLGVVPDAVVGHSQGEIAAAVVAGGLS
                     LEDGARAVVFRSRVAEEVLSGGGIASVRLSRAEVEERLAGGGGGLSVAVVNAPSSTVVA
                     GELGELERFVAACEAEGVRARRLEFGYASHSVFVEPARGRLLEALADVRPVSGEIPFYS
                     TVEAGVVDTASLDAEYWFGNLRRPVRFQETVEQLLADGFRVFVECGAHPVLTGAVQETA
                     ESVGRQVCAVGSLRR"
     CDS_motif       21738..21806
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0007"
                     /evalue="2.90E-08"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE248_RS10115"
                     /protein_end="602"
                     /protein_start="579"
                     /score="26.1"
                     /tool="antismash"
                     /translation="EREDVAQPASFAVMVSLAALWRS"
     CDS_motif       21810..21920
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0008"
                     /evalue="1.60E-16"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE248_RS10115"
                     /protein_end="640"
                     /protein_start="603"
                     /score="52.2"
                     /tool="antismash"
                     /translation="GVVPDAVVGHSQGEIAAAVVAGGLSLEDGARAVVFRS"
     CDS_motif       22026..22067
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0009"
                     /evalue="1.20E-02"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="IE248_RS10115"
                     /protein_end="689"
                     /protein_start="675"
                     /score="8.4"
                     /tool="antismash"
                     /translation="AVVNAPSSTVVAGE"
     CDS_motif       22272..22319
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0010"
                     /evalue="2.40E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="IE248_RS10115"
                     /protein_end="773"
                     /protein_start="757"
                     /score="16.4"
                     /tool="antismash"
                     /translation="LDAEYWFGNLRRPVRF"
     aSDomain        22674..23174
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10115_PKS_DH.1"
                     /evalue="4.20E-50"
                     /label="IE248_RS10115_PKS_DH.1"
                     /locus_tag="IE248_RS10115"
                     /protein_end="1058"
                     /protein_start="891"
                     /score="162.3"
                     /tool="antismash"
                     /translation="HPLLSGALPLAESGELLLVGRISPASHSWIADHTVAGTALLPGTA
                     FVGMALHAAAVVGCAGVEELSIEAPLPVHGGIRLQVVIDEPDSSDRRRVSVFARPEAED
                     GDTGRWTRHATGVLTPAAAPDPGRPQWSREAWPPSGSVRAEAAELYDRFSALGYEYGEV
                     FAGV"
     CDS_motif       22758..22835
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0011"
                     /evalue="6.10E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE248_RS10115"
                     /protein_end="945"
                     /protein_start="919"
                     /score="28.4"
                     /tool="antismash"
                     /translation="WIADHTVAGTALLPGTAFVGMALHAA"
     aSDomain        24216..24752
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10115_PKS_KR.1"
                     /evalue="2.00E-59"
                     /label="IE248_RS10115_PKS_KR.1"
                     /locus_tag="IE248_RS10115"
                     /protein_end="1584"
                     /protein_start="1405"
                     /score="192.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGATGTLGSLLARHLVTAHGVRHLLLLSRSGRDAGRAAEL
                     ERELTGLGAEFQLLSCDATDRVALREALATVPAAHPLTAVIHTAGVLDDGVVEALTPER
                     LDRVLRPKTDAALNLHELTAGMPLKAFVLYSGAVGLLGGAGQANYAAANAFLDGLAQYR
                     HAQGLPAVSLAWGLWS"
     CDS_motif       24219..24320
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0012"
                     /evalue="1.60E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE248_RS10115"
                     /protein_end="1440"
                     /protein_start="1406"
                     /score="27.1"
                     /tool="antismash"
                     /translation="TVLVTGATGTLGSLLARHLVTAHGVRHLLLLSRS"
     CDS_motif       24597..24707
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0013"
                     /evalue="5.00E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE248_RS10115"
                     /protein_end="1569"
                     /protein_start="1532"
                     /score="54.4"
                     /tool="antismash"
                     /translation="LKAFVLYSGAVGLLGGAGQANYAAANAFLDGLAQYRH"
     aSDomain        25092..25346
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10115_PKS_PP.1"
                     /evalue="9.90E-28"
                     /label="IE248_RS10115_PKS_PP.1"
                     /locus_tag="IE248_RS10115"
                     /protein_end="1782"
                     /protein_start="1697"
                     /score="88.3"
                     /tool="antismash"
                     /translation="LAGLDAAGRRDELLAVAQAQLADVLGFTDKTAVDPVRSFREIGLD
                     SLTAVELRNRLDAVTGLRLSSALVFDHPNLDALAGHLAEL"
     CDS_motif       25137..25202
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10115_0014"
                     /evalue="6.00E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="IE248_RS10115"
                     /protein_end="1734"
                     /protein_start="1712"
                     /score="-3.0"
                     /tool="antismash"
                     /translation="VAQAQLADVLGFTDKTAVDPVR"
     aSDomain        25386..25634
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10115_PKS_Docking_Cterm.
                     1"
                     /evalue="3.30E-07"
                     /label="IE248_RS10115_PKS_Docking_Cterm.1"
                     /locus_tag="IE248_RS10115"
                     /protein_end="1878"
                     /protein_start="1795"
                     /score="23.0"
                     /tool="antismash"
                     /translation="LSGVDALDRAVRGMAADDTRRDAVRRRLTELLAVVGDAPRDGDRS
                     TRTAAGTGSHGVQAGPDLLGQLDSASDDDLFAFIEDQL"
     gene            <25743..31655
                     /locus_tag="IE248_RS10120"
                     /old_locus_tag="GCM10010336_20590"
                     /pseudo=""
     CDS             <25743..31655
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (1-28). E-value:
                     5.6e-14. Score: 43.4. Matches aSDomain:
                     nrpspksdomains_IE248_RS10120_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (33-456). E-value:
                     3e-178. Score: 585.0. Matches aSDomain:
                     nrpspksdomains_IE248_RS10120_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (562-857). E-value: 6.4e-108.
                     Score: 352.5. Matches aSDomain:
                     nrpspksdomains_IE248_RS10120_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (956-1136). E-value: 2.2e-51.
                     Score: 166.4. Matches aSDomain:
                     nrpspksdomains_IE248_RS10120_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1482-1662). E-value: 2.5e-57.
                     Score: 185.7. Matches aSDomain:
                     nrpspksdomains_IE248_RS10120_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1800-1872). E-value: 4.9e-32.
                     Score: 102.1. Matches aSDomain:
                     nrpspksdomains_IE248_RS10120_ACP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1885-1967). E-value:
                     3.8e-12. Score: 38.9. Matches aSDomain:
                     nrpspksdomains_IE248_RS10120_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173985.1"
                     /locus_tag="IE248_RS10120"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_20590"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="mod_KS (E-value: 4e-220, bitscore: 726.8,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.1e-88, bitscore:
                     292.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 9.9e-107, bitscore:
                     352.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.3e-59, bitscore:
                     196.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-13, bitscore:
                     46.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NDDKIRDYLKRVVAELHSTRQRLNALEDNAREPIAIVGMSCRLPG
                     GVTTPESLWELVDSGTDAVSPFPDDRGWDLDALHHPESGAVHSREGGFLHDSADFDAEF
                     FGISPREALAMDPQQRLLLETAWEVFERAGIDPASVRGSRTGVYAGVMYHDYGARLNEI
                     PPGLEGYLVNGSAGSIASGRVAYTLGLEGPAITVDTACSSSLVAVHLAAQALRQRECDM
                     ALAGGATVLSTPDLFTDFARLGGLASDGRCKAFSDAADGTSFAEGAGMLLLMRLSDAVD
                     KGHTVLAVIRGSAVNQDGASNGLTAPNGLAQQRVIREALANADLGPDQIDAVEAHGTGT
                     RLGDPIEAQALLHTYGTSRSPERPLLLGSLKSNIGHTQAAAGVAGIIKTVLAMRHGRLP
                     RTLHVTRPSSRVDWSAGAVELLTQTQDWPGQGDAPRRAGVSSFGASGTNAHLILEGVPD
                     SDDTAAEREPSAGGGAWLLSGRTEAALRAQARRLHGHLAARPHVSPAAVGRTLARSRTA
                     FEHRAVVIGQDTAALLSGLRELASGAAHGPGVITGRAARGRRTALLFTGQGSQRPGAGR
                     RLYERYEVFARALDETAAELDRHLDRPLREVMFAEPGSATAGLLDRTEYTQPALFALEV
                     ALFELVSAWGLRPDALLGHSVGELAAAHVAGVFTLPDAARLVTARGRLMGELPAGGAMA
                     AIQAGGPEIEETITALTARRQARIAVAALNGPDATVISGDEDAVAELAALWRERGRRAK
                     VLPVSHAFHSPRMDAALEPFARIARDVSYAEPRIPVVSNLTGEVASAATLCTPEYWVRH
                     AREAVRFSDGFRTLRDQGIDTFVELGPDGVLSALGRDCLREEEQDAPHQDGSTDRDTAG
                     SPADGQERPVLTVPLLRRDRDETTTCLGALAAVHTHGVPLDLAAVHGDGPAVDLPTYAF
                     QRTRYWLDVPAPAAGLTTTGLEAADQPLLPAAIDLPDGEGTVRTGLLSVRTHPWIADHR
                     VQNRTVVPGAALLDIAAWAGTEAGCPRVAELTFATPLVLPESGEGVRLRVTLSGPDAEG
                     IRTIRIDSRPADAARAADAPSDWTRHASGTLTPGTEEAGDGADVPADLLGVWPPADATP
                     VALDADAVAAEYRRLADAGVTYGPVFRGLRAVWRRGEEIFAEVRLPGQAAADAPRYGMH
                     PALLDALAHATGFGEQFTEAHGLLPFSWSDVRIHVRGTDSLRVRIAPAGPDAVTVAAAD
                     PAGRPALTARSLTLRPVPAHRFPSPQERSTPLYRLEWTSASAPVTGHARPRPAAAEWGV
                     LGDAGPALLEGVRDGAQAPVRTYDDLAALAASDTPLPDHVLVELGHDGDDLAAGAHDLA
                     ERALAVVQGWLAHARFTDARLVVLTHGAVAAGTSAVRPASAVAWGLLRSAQSEHPGRFV
                     LVDADPSDPAASYRSLSRAVTSGASQLALRGDEILVPRLTHGANGQGAAAGPLGDATEP
                     EAAAAMGSAPSGSPSGPWRADGTVLVTGGTGTLGKAVARHLVTKHGVRHLILAGRRGAD
                     APGAAGLAAELTDLGAVVNIVRCDAADRSALEGLLAAVPAAHPLTAVVHTAGVLDDGIV
                     TAQTLQRVSAVLRAKADAVTHLHELTSDLDLSAFVLFSSAAGTLGSPGQSGYAAANSFL
                     DAFAAWRRAQGLPAVSLAWGLWGDGGDGDGGSAGADGMGASLAAADLARLRRSGILPLD
                     PAEALELFDEACAPSRTEAVLLPIRLDLAGLRARAARGTVHAGVVPEVLHALVPPPAGA
                     GPSSGAGTPDPAAGQEPPTTAAASGTLAEQLAGKPRGERLAVLRELVRTEIASVLGHAD
                     AQRVQLQFSFKEAGFDSLTAVELRNRLTAVTGTRLPATLVFDHPTPAALVDHLEQELPK
                     GGQKLPADVPAVLEALDRIRDGLATAVTDDNGRAHVAERLQELLGTLAPPVAGVRPVNG
                     SNGHDGQGPDELSVGERLAASSDDELFDLFDSDFRSM"
     aSDomain        25749..25829
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10120_PKS_Docking_Nterm.
                     1"
                     /evalue="5.60E-14"
                     /label="IE248_RS10120_PKS_Docking_Nterm.1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="28"
                     /protein_start="1"
                     /score="43.4"
                     /tool="antismash"
                     /translation="DDKIRDYLKRVVAELHSTRQRLNALED"
     aSDomain        25845..27113
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10120_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.00E-178"
                     /label="IE248_RS10120_PKS_KS.1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="456"
                     /protein_start="33"
                     /score="585.0"
                     /tool="antismash"
                     /translation="IAIVGMSCRLPGGVTTPESLWELVDSGTDAVSPFPDDRGWDLDAL
                     HHPESGAVHSREGGFLHDSADFDAEFFGISPREALAMDPQQRLLLETAWEVFERAGIDP
                     ASVRGSRTGVYAGVMYHDYGARLNEIPPGLEGYLVNGSAGSIASGRVAYTLGLEGPAIT
                     VDTACSSSLVAVHLAAQALRQRECDMALAGGATVLSTPDLFTDFARLGGLASDGRCKAF
                     SDAADGTSFAEGAGMLLLMRLSDAVDKGHTVLAVIRGSAVNQDGASNGLTAPNGLAQQR
                     VIREALANADLGPDQIDAVEAHGTGTRLGDPIEAQALLHTYGTSRSPERPLLLGSLKSN
                     IGHTQAAAGVAGIIKTVLAMRHGRLPRTLHVTRPSSRVDWSAGAVELLTQTQDWPGQGD
                     APRRAGVSSFGASGTNAHLILEGV"
     aSModule        25845..31361
                     /complete
                     /domains="nrpspksdomains_IE248_RS10120_PKS_KS.1"
                     /domains="nrpspksdomains_IE248_RS10120_PKS_AT.1"
                     /domains="nrpspksdomains_IE248_RS10120_PKS_DH.1"
                     /domains="nrpspksdomains_IE248_RS10120_PKS_KR.1"
                     /domains="nrpspksdomains_IE248_RS10120_ACP.1"
                     /locus_tags="IE248_RS10120"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       26319..26366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0001"
                     /evalue="1.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE248_RS10120"
                     /protein_end="207"
                     /protein_start="191"
                     /score="20.6"
                     /tool="antismash"
                     /translation="GPAITVDTACSSSLVA"
     CDS_motif       26742..26786
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0002"
                     /evalue="4.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE248_RS10120"
                     /protein_end="347"
                     /protein_start="332"
                     /score="12.4"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       26847..26891
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0003"
                     /evalue="2.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE248_RS10120"
                     /protein_end="382"
                     /protein_start="367"
                     /score="10.6"
                     /tool="antismash"
                     /translation="GSLKSNIGHTQAAAG"
     aSDomain        27432..28316
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10120_PKS_AT.1"
                     /evalue="6.40E-108"
                     /label="IE248_RS10120_PKS_AT.1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="857"
                     /protein_start="562"
                     /score="352.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQRPGAGRRLYERYEVFARALDETAAELDRHLDRPLREV
                     MFAEPGSATAGLLDRTEYTQPALFALEVALFELVSAWGLRPDALLGHSVGELAAAHVAG
                     VFTLPDAARLVTARGRLMGELPAGGAMAAIQAGGPEIEETITALTARRQARIAVAALNG
                     PDATVISGDEDAVAELAALWRERGRRAKVLPVSHAFHSPRMDAALEPFARIARDVSYAE
                     PRIPVVSNLTGEVASAATLCTPEYWVRHAREAVRFSDGFRTLRDQGIDTFVELGPDGVL
                     SALGRDCLREEEQD"
     CDS_motif       27435..27482
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0004"
                     /evalue="1.20E-04"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="579"
                     /protein_start="563"
                     /score="14.9"
                     /tool="antismash"
                     /translation="FTGQGSQRPGAGRRLY"
     CDS_motif       27603..27662
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0005"
                     /evalue="1.30E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="IE248_RS10120"
                     /protein_end="639"
                     /protein_start="619"
                     /score="12.1"
                     /tool="antismash"
                     /translation="LDRTEYTQPALFALEVALFE"
     CDS_motif       27678..27797
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0006"
                     /evalue="8.40E-24"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE248_RS10120"
                     /protein_end="684"
                     /protein_start="644"
                     /score="75.9"
                     /tool="antismash"
                     /translation="GLRPDALLGHSVGELAAAHVAGVFTLPDAARLVTARGRLM"
     CDS_motif       27906..27944
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0007"
                     /evalue="6.30E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="IE248_RS10120"
                     /protein_end="733"
                     /protein_start="720"
                     /score="13.0"
                     /tool="antismash"
                     /translation="AALNGPDATVISG"
     CDS_motif       28167..28202
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0008"
                     /evalue="1.50E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="IE248_RS10120"
                     /protein_end="819"
                     /protein_start="807"
                     /score="15.1"
                     /tool="antismash"
                     /translation="YWVRHAREAVRF"
     aSDomain        28614..29153
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10120_PKS_DH.1"
                     /evalue="2.20E-51"
                     /label="IE248_RS10120_PKS_DH.1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="1136"
                     /protein_start="956"
                     /score="166.4"
                     /tool="antismash"
                     /translation="PLLPAAIDLPDGEGTVRTGLLSVRTHPWIADHRVQNRTVVPGAAL
                     LDIAAWAGTEAGCPRVAELTFATPLVLPESGEGVRLRVTLSGPDAEGIRTIRIDSRPAD
                     AARAADAPSDWTRHASGTLTPGTEEAGDGADVPADLLGVWPPADATPVALDADAVAAEY
                     RRLADAGVTYGPVFRGL"
     CDS_motif       28695..28763
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0009"
                     /evalue="1.60E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="IE248_RS10120"
                     /protein_end="1006"
                     /protein_start="983"
                     /score="27.1"
                     /tool="antismash"
                     /translation="WIADHRVQNRTVVPGAALLDIAA"
     aSDomain        30192..30731
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10120_PKS_KR.1"
                     /evalue="2.50E-57"
                     /label="IE248_RS10120_PKS_KR.1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="1662"
                     /protein_start="1482"
                     /score="185.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGGTGTLGKAVARHLVTKHGVRHLILAGRRGADAPGAAGL
                     AAELTDLGAVVNIVRCDAADRSALEGLLAAVPAAHPLTAVVHTAGVLDDGIVTAQTLQR
                     VSAVLRAKADAVTHLHELTSDLDLSAFVLFSSAAGTLGSPGQSGYAAANSFLDAFAAWR
                     RAQGLPAVSLAWGLWGD"
     CDS_motif       30195..30296
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0010"
                     /evalue="6.50E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="1517"
                     /protein_start="1483"
                     /score="31.6"
                     /tool="antismash"
                     /translation="TVLVTGGTGTLGKAVARHLVTKHGVRHLILAGRR"
     CDS_motif       30579..30683
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10120_0011"
                     /evalue="1.20E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="IE248_RS10120"
                     /protein_end="1646"
                     /protein_start="1611"
                     /score="62.9"
                     /tool="antismash"
                     /translation="AFVLFSSAAGTLGSPGQSGYAAANSFLDAFAAWRR"
     aSDomain        31146..31361
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10120_ACP.1"
                     /evalue="4.90E-32"
                     /label="IE248_RS10120_ACP.1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="1872"
                     /protein_start="1800"
                     /score="102.1"
                     /tool="antismash"
                     /translation="ELVRTEIASVLGHADAQRVQLQFSFKEAGFDSLTAVELRNRLTAV
                     TGTRLPATLVFDHPTPAALVDHLEQEL"
     aSDomain        31401..31646
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10120_PKS_Docking_Cterm.
                     1"
                     /evalue="3.80E-12"
                     /label="IE248_RS10120_PKS_Docking_Cterm.1"
                     /locus_tag="IE248_RS10120"
                     /protein_end="1967"
                     /protein_start="1885"
                     /score="38.9"
                     /tool="antismash"
                     /translation="VLEALDRIRDGLATAVTDDNGRAHVAERLQELLGTLAPPVAGVRP
                     VNGSNGHDGQGPDELSVGERLAASSDDELFDLFDSDF"
     gene            31710..>33535
                     /locus_tag="IE248_RS10125"
     CDS             31710..>33535
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (14-42). E-value:
                     3.5e-13. Score: 40.9. Matches aSDomain:
                     nrpspksdomains_IE248_RS10125_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (46-474). E-value:
                     3.1e-183. Score: 601.4. Matches aSDomain:
                     nrpspksdomains_IE248_RS10125_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743411.1"
                     /locus_tag="IE248_RS10125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_190030525.1"
                     /sec_met_domain="mod_KS (E-value: 9.2e-231, bitscore:
                     761.8, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.1e-95, bitscore:
                     314.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENSTVSSATPATNEEKLRDYLRRAMADLHEAREQISRTESARHE
                     PIAIVGMGCRLPGGVSSPEGLWDLVASGVDAVSPFPTDRGWDVAGLFDPEPGVPGRTYV
                     REGGFLHGAGEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPHSLRGSRTGV
                     YAGVMYHDYGSTVAGSAAPDDETAGFLGIGTSGSVASGRISYVLGLEGPAVTVDTACSS
                     SLVALHLAVRALRSGECDLALAGGVTVMAEPGVFVEFSRQRGLAADGRCKAFSDSADGT
                     GWAEGVGVLAVERLSDAVRHGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALA
                     DARLGVGDVDVVEAHGTGTRLGDPIEAQALLATYGQRDAGRPLWLGSLKSNVGHTQAAA
                     GVAGVIKMVMAMRDGVLPKTLHVDEPSAEVDWSAGAVSLLTEQEPWPEVGRPRRAAVSS
                     FGLSGTNAHVVVEEAPAPEVGEVGVGVSPAVVPVVVSGRSAGVVRELASRMGEIAGSGR
                     LVDVGLSSVVSRSVFEHRSVVLAEDSAELNTGLDALAAGVPSSGVVSGVVSGEGGRSVF
                     VFPGQGTQWVGMAVRLWAESGVFAESMARCEAA"
     aSDomain        31752..31835
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10125_PKS_Docking_Nterm.
                     1"
                     /evalue="3.50E-13"
                     /label="IE248_RS10125_PKS_Docking_Nterm.1"
                     /locus_tag="IE248_RS10125"
                     /protein_end="42"
                     /protein_start="14"
                     /score="40.9"
                     /tool="antismash"
                     /translation="EEKLRDYLRRAMADLHEAREQISRTESA"
     aSDomain        31848..33131
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS10125_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.10E-183"
                     /label="IE248_RS10125_PKS_KS.1"
                     /locus_tag="IE248_RS10125"
                     /protein_end="474"
                     /protein_start="46"
                     /score="601.4"
                     /tool="antismash"
                     /translation="IAIVGMGCRLPGGVSSPEGLWDLVASGVDAVSPFPTDRGWDVAGL
                     FDPEPGVPGRTYVREGGFLHGAGEFDAGFFGISPREALAMDPQQRLLLETSWEALERAG
                     IDPHSLRGSRTGVYAGVMYHDYGSTVAGSAAPDDETAGFLGIGTSGSVASGRISYVLGL
                     EGPAVTVDTACSSSLVALHLAVRALRSGECDLALAGGVTVMAEPGVFVEFSRQRGLAAD
                     GRCKAFSDSADGTGWAEGVGVLAVERLSDAVRHGRRVLAVVRGSAVNQDGASNGLTAPN
                     GPSQQRVIRQALADARLGVGDVDVVEAHGTGTRLGDPIEAQALLATYGQRDAGRPLWLG
                     SLKSNVGHTQAAAGVAGVIKMVMAMRDGVLPKTLHVDEPSAEVDWSAGAVSLLTEQEPW
                     PEVGRPRRAAVSSFGLSGTNAHVVVEEAP"
     CDS_motif       32103..32129
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10125_0001"
                     /evalue="7.60E-03"
                     /label="PKSI-KS_m2"
                     /locus_tag="IE248_RS10125"
                     /protein_end="140"
                     /protein_start="131"
                     /score="9.2"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       32340..32387
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10125_0002"
                     /evalue="2.50E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE248_RS10125"
                     /protein_end="226"
                     /protein_start="210"
                     /score="22.4"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       32763..32807
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10125_0003"
                     /evalue="7.90E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="IE248_RS10125"
                     /protein_end="366"
                     /protein_start="351"
                     /score="14.5"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       32865..32909
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10125_0004"
                     /evalue="8.40E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="IE248_RS10125"
                     /protein_end="400"
                     /protein_start="385"
                     /score="11.8"
                     /tool="antismash"
                     /translation="GSLKSNVGHTQAAAG"
     CDS_motif       33432..33485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS10125_0005"
                     /evalue="7.30E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE248_RS10125"
                     /protein_end="592"
                     /protein_start="574"
                     /score="27.4"
                     /tool="antismash"
                     /translation="VFVFPGQGTQWVGMAVRL"
ORIGIN
        1 atcagggggc cagcgtggag ggcacccgct cgtcggctct gcgggtcacc tcgtgtcccc
       61 gctccagggt gacccggacg atgtcacaga cccgccggat gtcctcacgg gagacggtgg
      121 gaccggtggg cagggcgagt accctctgcg cgagccgttc ggtgtgcggc agggtgaccg
      181 gccgctccga gcggtagagc tccatctcat ggcatccggg ggagaagtac cgctggcaca
      241 ccacgttctc cgctctgagc acccagtcca gcaggtcacg gtggacaccg gtcaccgcgg
      301 cgtccacctc cacgatcaga tagtggtagt tgttgcgctc ggcacggttg aattccatga
      361 cgttcagccc ggcgatacca gcgagttccg accggtagtc gtcgtagttg gcctcgttcc
      421 ggcggaccgt ctcctcgaag gcgtcgagtg aggtcaggcc catcgcggcg gcggcttcgg
      481 tcatcttccc gttggtgccc gtctccgtgg acacgcgtcc ctgggcgaac ccgaagttgt
      541 gcatcgcgcg gacccgttgg gccagttcct cgtcgtcggt caccaccgcg ccgccctcga
      601 aggcgttcac caccttggtg gcgtgaaaac tgaacacctc ggcttgcccg aagccaccga
      661 tcggctgccc ttccgccgtg cagccgagcc cgtgcgcggc atcgtagaac agcttgatgc
      721 cgtgatcggc cgcgaccttc gcgagctggt cgaccgcgca cggacgaccc cacagatgga
      781 cgggaacgat cgcactggtg cgaggggtta tcgccgcctc gaccagtgcg gggtccaggc
      841 aactggtggc cgggtcgatg tcacagaaga ccggggtcag acccagccag cggaatgcct
      901 gggcggtcgc cgggaaggtc agtgacggca tgatgacctc cccggacaga tccgcggcgc
      961 gggccagcag ctggagggcg acggtcgcgt tgcaggtcga cacgcaatag cgcacgccgg
     1021 ccagctccgc cacccgctgc tcgaactccc gcgccagcgg tccgccgttg gtgagccact
     1081 ggtggtccag cgcccagttc acgcgatcga agaaccgggc ccggtcaccg acgttgggcc
     1141 gccccacgtg aagcggttgc aggaatgccg aaggaccgcc gaatacagcg agatcaccga
     1201 cattgcgttt caatggtcat accttcccgg tgcgtgcgaa aaggcgcacc cggcagcggc
     1261 cggcacaaag gattcggacg tgccgaagag acagagaccg cagtgcacga aactctctgt
     1321 cgcgcacgtt cgagaggagc gcacggactc gatcagtgcg cgcggcgcca gtagacgcct
     1381 gtcacgtcca ccgtctcgat cggttcgtcg atgccgtgtt cgttccggta gtcatggacg
     1441 gcctgcttgc acgccgggat caggtagtcg tccacgatca cgaagccgcc cacggagacc
     1501 ttggggtaga gattgaccag cgcgtccatg gtcgactcgt acaggtcgcc gtccagccgc
     1561 aggaccgcga gctgatcgat cggtgcattc ggcagcgtgt cggcgaacat gccgggcagg
     1621 aacttgacct ggtcgtccag caggccgtag cgagcgacgt tctgccgcac ctgctcctcg
     1681 gagcagctca gcacccagtt caggttgtgg aactccatgg cctggtcgag cgggtgactg
     1741 tcctcggacg tcacggggac accggcgaac gagtcggcga gccatacgtt ccggtcttcc
     1801 acgccgtgcg ccttgaggag cgcgcgcatc aggatgcagg cgccaccgcg ccacacgccg
     1861 gtctcgatga aatcgccggg aacaccgtcc cggagcacct gctccacaca cttctggatg
     1921 ttgtccaggc ggtgcaggcc gatcatggtg tgcgcgaccg tcggcacgtc cagaccttcg
     1981 gcccggtggc cggcgtcgaa cctcccgtgg tcgacggccg agccgggcgc gtccggacgc
     2041 atgctgtccg ccagatcctt gtccaggacg ttcattccga ccgggaaagt cgggtgatcc
     2101 ccataaatag tgttcgtcac gacacgtttt atgaggtcca cgtaaagctc gtgagtctgc
     2161 acagtcacaa tgtcccccag ctggataatc aagcggagaa ataaattctt caaccgaccc
     2221 taacggctat ccgggagggg ggcaaggatt catctcggtg gtatcggtaa atgcacggcc
     2281 atgcggagcg gaaggctcgg taattcattc tcaggccgtc gcggtcacgt caccgcaaga
     2341 aaccgcgcgt gtccccccag cccgcggcga catccgcctc gagctggttg agccgtgccg
     2401 tgaccacttg gtcgaacccg tccatgaagt actcgtcacc gtcgtgcggc gctatccggc
     2461 ggtcgtcgtt gacgaaccgc tcgaccacct ccgccaggga ggtgcccggc cccacccggc
     2521 ctgcgatgta gcggtctgct ccgtcgagat ccgggaaccc ggcctcccgg tacaggtaca
     2581 catcacccag caggtcgacc tgcacggaga cctggggatg cacggacggg cgcattgtcc
     2641 cgggcctgat cctcagcagt tcggcgtccg cgccggtcct caggctgtgc aacgcgtagc
     2701 cgtagtcgac gttcaacgtg ggggtccggc ggctcacctg ctcctcgaag gcgaggagtc
     2761 cttcgtggag ttccgtgcgc tcggcctcgg acaacctgcc gtctccccgg ccgctgtagt
     2821 cctcgcgcac gttcaggaag tccactggcc ggtccggcgc cgcctcgttg agctcggcga
     2881 tgaagccgac gaggtcgagc aggcgatgca cgcgcccggg cagcacgatg tagctgagcc
     2941 cgacccgtat cgggctctcc cgctcggtac gtagctgctg gaagcgttgc aggttggcgc
     3001 ggaccctgcc gaaggaggcc cgcttgcccg tggtctcctc gtactcctcg tcattgagcc
     3061 cgtacagcga tgtgcgcacc gcgtgcagat cccacacccc gggctgtctg gccagcgtcc
     3121 gctctgtgag cgcgaaggag ttcgtgtaca ccgtcgggcg caggccgcgg gccgccgcac
     3181 gactgctgag cgcgcccaac cccgggttgg tcagaggctc caggccaccg gagaagtaca
     3241 tggcgtacgg attgccggcc ggtatctcgt cgatgacgga ctcgaacagc gcgttaccgg
     3301 actccagcgc cgacggatcg tagcgagcgc cggtcacacg gacgcagaag tggcagcgga
     3361 acatgcagct cggccccggg tacaggccca cgatgtacgg gaagaccggc ttgtgcgcca
     3421 gtaccgcgtc gaagactccc cgctgctcca gaggcagcag ggtgttctgc cagtacttgc
     3481 ccgccggccc ggtctccacg gcgtgccgaa gctgggggac gagaccgaag aagccgagga
     3541 gacggctgaa ggaagcccgg tcgacgtcca gcaaccggcg gacgtcctcg aggggagtga
     3601 acgggtggtt cccgtagtgc tcggccagct gtacgagccg gcgggcgacc gccggggcct
     3661 cgtcagcgcc gacgtggccg tcggcggtca gggcgcgccg caccgtctgg accgctgccg
     3721 cgaggtcggc gccggggcga gcgcaggtgg cgaccggatc ggccggggtg gaggcttgag
     3781 aggtcatcct tcgtgtccaa tcgtctgcgt ccggtgctcg gttcggttgc cagggaacgg
     3841 ggacgggacg gcgccctgac gcggcggggc ggtcaccggg gcagcaccgt gacgggggtg
     3901 gtcagggacg tcttggcggc ggagggcccc acgtacacgg tcctccggcc ggtgcccagc
     3961 cgccagctgc cggcggaggt gtcccagtag cgcagttgct cctcgtcgac ggggacggtg
     4021 acgcgccgct gctctcccgg ttcgagggtg accttgccga atccggcgag cttgcgcagc
     4081 gcctggggag cctgggtgtc cgggctggcg ccgaggtaga cctggacggt ctcccggccc
     4141 gcgcggtcac cggtgttacg gaccgtgacc gtggcgtcga gtccccgggg ggtgcgcacc
     4201 acggacaggt cgctgtaggc gaaggtggtg taggacaggc cgtacccgaa cgggaagagc
     4261 ggtgctacgc cggtccggtc gtaccagcgg tagccgacat ccagtccctc ggagtaggtc
     4321 tccttgccgt cgacgcccgg gtagcggtgc gggtcgccgg ccatggggtg gccggtctcg
     4381 gtggcgggga aggtctgcgt cagccggccg ctggggtcgg cgtcgccgaa cagcagcgcg
     4441 gcggtggcct ccgcgccctc ttgtcccgga taccacatct ccagcacggc ggcggtgtcg
     4501 cgcagccagg gcatgagcac cgaggaaccg gtgttgagga cgacgatcgt gcgggggttg
     4561 accttggtga ccgccgcgat gagctcgtcc tgccggccgg gcagggacag cgaggtccgg
     4621 tcgacgcctt cggcgctgtc gtcctgggcg aagacgatgg cggtgcgggc cttggccgcc
     4681 gccgcgacgg cgcggtcgaa gtcggtccgg gccgcctccg gagtgaccca gctcagttcc
     4741 accgacagtg gggtcttttc gaaggcccac ccgttcatgg tgacctcgtg cgtgccgcgg
     4801 gtcagatgca tcgtggtggt gacggtgccg aacgcctcgg tgccgaggac agcggactgt
     4861 cccgcgatct gcaggttggc gacccctccg acggcgctga aggcgatctt gtagtcaccg
     4921 tcggcgggaa cggtgagctg gcccttgtag aagacgccct ggccgccggg ctgcaactgc
     4981 ttcccgccct tgaaggcggg agcgagggag ctgtcgggca cgggcacgcc gacgaggtcc
     5041 tcgcccggct cgtagacgac cgtggccttg tcgccggcgc gccgttcgat ggcgtcgacg
     5101 ggggcggtcg cccggtcggg tatgacgtgc gcgctgccgt taccggtgac cttggggtgc
     5161 ttcgcgctgt tgccgatgac ggcgatgtcc gcggccttcc cgccggccag gggcaacgtc
     5221 cgttgctcgt tgcgcagcag cacgccgccg ttctcggcga tggtgcgggc cgtcttacgg
     5281 ccggcctcgg ggtcgcgctg cgggcgctcg gtcgccttgc cgtcgagcag gccgaaacgc
     5341 tccatctggc cgaggatgcg gatgacggac cggtcgagcg tcgcctcggg gatgctgccg
     5401 tcctcgatgg ccgtcttgag cgcggaggag aagtacttgg agtccggcac cggctggccc
     5461 agggccagct cgacgcccag ttcctggtcg aggcccttgg tgatgtcgct ggtggcgtgg
     5521 gtcgccagcc agtcggacag cacccagccg cggaagtccc actgttcgcg cagcacgtcc
     5581 tgcaacagat gctcgttgct gcaggcgtgc gtgccgttga cgctgttgta cgagcacatc
     5641 accgaggcgg ctcccgcctt gacggcgctg cggaaggccg gcagctccac ctcctggagc
     5701 gtctgctcgt cgacggtggc gtcgatggtc tcccgctggt actcctggtt gttcgcggcg
     5761 aagtgcttga ccgtggccat caggccctgg tcctggatgc cgcggacctc gtcggcggcc
     5821 atccgggacg acagcagcgg atcctcgctg tacgtctcga agttccgccc ggcgtggggc
     5881 acccggatga tgttggtcat gggaccgagg acgatgtcct gcccgagggc tcgtccctcc
     5941 cggcccagga cggtgccgta ctcctcggca aggtgttcgt cgaacgtgga ggcgagcgcc
     6001 acgggtgtgg gcatggcggt ggcggtaccg ccgagcaggc ggatgccgac cgggccgtcg
     6061 gcggtgcgca gctcgggtat gccgagtcgt tggacgcccg gcaggtagcc gatgccggtc
     6121 atggtcggcc cgcccacagg cccggtggtc cagtggacga acgagatctt ctcgtcgagg
     6181 gtcatcttcg ccaccaggct gcgcacccgc ggcgtcccgg gaccggcggc cggagcgccg
     6241 gtggcggaag gggcggtgag gagaccgccg acgcacaggg ctgcgagagc gtagccgacg
     6301 gcgcgccggg tttggcggcc cgttctcctt gtgccgaaca gcatgctgac acatgtcctt
     6361 tctgctgagg ctgccgtcct cgtaggggca ggggcattcg tctccgtagg cacgacccgg
     6421 tcgccgtccg tacggcctcg gcgcggcccc gggcggaata cgcgtgtgag gccgggtccg
     6481 ctcgcctcag tccgtgtctc aacgctcacc aggccacgag catcgtgcgc ggtccccgca
     6541 ccaccatctg cgtcttccac tcgacggcct gggcgaggtg cagcccgggg agtccgtcga
     6601 gcagggtccg cagcgcctcc tggagttcca gccgcgcgag ggacgcaccg aggcagtgat
     6661 gcggaccgtg cccgtaaccc aggtgctgac gggcgtcgtc gcgggtgatg tcgagcacgc
     6721 cgggcgaacg gaagcgcagg gcgtcccggt tggccgcgtt catctggacc agaaccggct
     6781 cgcccgcccg caccagggtc ccgcccactt cgacgtcctc ggtggcgtag cgcgggaacc
     6841 ccgcttggct gcccagcgga acgaatcgcg tcagctcttc caccgcgttg tccagcaggt
     6901 ccggacggtc gcggaggagg gccaactggt ccggctgttc gagcaggagc aggacgaagt
     6961 tgctgatctg gctggccgtg gtctcgtgtc cggcgaacag caggaagacg atcaggttga
     7021 ccaattcctc ctgcgagagc cggccctcgg cgtcgcgggc ctccacgagt gccgatacga
     7081 ggtcgtcctg cggagcggcg cggcggtctg cgatcaggtc cgccaggtag ccggtcaact
     7141 cgccggccag ccgcacatgg tcctcggcgg tgagcgagct ggtggacatc gctatgtcgc
     7201 accagccgcg gaacagcgca cggtcctcct cgggcacgcc cagcaggccg cagatgaccg
     7261 ccacggggat cgggacggcg tagtgctcca cgaggtcggc aggtgcgccg agcgccgtca
     7321 tgtcctggag cagcgactcg gtcatcttcc tgacacgcgg ccgcatggcc tccacgcggc
     7381 gcggagtgaa tgctctggtc accagcccgc gcagcctggt gtggtcaggt gcgtccatgc
     7441 cgaggatgcc gttgggggtc cgcagttccc gcatgcgcgg tgcgtcgttc tccgcctccg
     7501 cggcgtggct gaaccgccgg tcgccgagta cgaaacgcgc gtcgtcgtaa cggcagacga
     7561 gccagctcgg ctccccgtac ggcatgtgga cccacaggag tcctgcgctc ttctgggcct
     7621 gctcgtacgc ctcgtccagg tccagtcccg tcgagcggct gaagggatag gagacaggtg
     7681 cggacttcgt gctggtcaat tcggacccca catcgagtcg gtcgggttct ttcgcgtcct
     7741 gggaaccgga gtgcggcggc cgcggctcgg gacggatcac tcagcggggt agccccacgt
     7801 gacgggaacc gcctcggggg tgcgcatgag ggagccggtc cgccagcgga gctcgctcgc
     7861 ggggacggac agccgcagcc ccggcaggcg ttcgaccagg gtgctcagca cgacctgcag
     7921 ttcaagccgt gccagggggg cgcccatgca gtagtgggcg ccgtgaccga agccgaggtg
     7981 cgggttctgg gcgcgtgtga agtcgaggga cgcggcaccg ggaaacgccg tgtcgtcgag
     8041 gttcgcggac gcgatcgagg tgatgaccgc ctcacccgcg cggatgagcg tgccgccgat
     8101 ctcgacgtcc tccagggcga tgcgggcgaa cccgtccgtg gtgctcagcg gggtgaagcg
     8161 cagcagctcc tcgacggcgg cgggaaccag gtccgggtcg gcgaccaggc gctcgtagag
     8221 ccggcggtcg tcgagcagga ggtggacgaa gttgccgatc tgggtggcgg tggtctcgta
     8281 gccgctgatc agcaggccgg cgcccagcat gagaagctcg gcctcggaga gccggtcgtc
     8341 ttcgtcgcgg gcctggacca tggtgctgag gaagtcgtcg gtgggccggg cgcggcgatc
     8401 ggccaccagc tcggccatgt aggcggtgaa gccctctgtc acccgctgca attccgcggg
     8461 acccagggag gaggagacca gcgcctcgga gaagttgcgg aagagatggc ggtcgtcgta
     8521 ggagacgccc agcagtctgc agatcacgga gatcgacacg ggcagcgcca gatcttccat
     8581 gatctcaccg gacggctcgt cgcgcgcgac catcccgtcg agcagctcat gggtgaaccg
     8641 cgagacctgc gggcgcagtt cctccacccg gcgggcggtg aacgccttcc cggccagccg
     8701 ccggagcctg gtgtgtccgg gcgggtccat ggagatgaga ccgccggcgg gcagcgggta
     8761 ctcggtaggc cggggcacat cacgtccggc cccggcctcc atgctgaacc gcgggtcgcc
     8821 caggaccgcc ttcacgtcgg cgtgccgggt cagcaaccag gcctcacccc cgtacggcat
     8881 acggatccgg gacacgggct cgtgctcccg cagatggctg tagagcggat ccagcgcgat
     8941 gccctcgggc agggagaagg ggtacgggcg agtctggtgg accggacaac tagacgtcat
     9001 ggacactctc tcggtcatac ggggcggcgg gaggacttga ggggagcggg cgcccgcatg
     9061 gcgagcccgg ttgccgtccg gatcgtccgg cacaccgctt cggcgtgctc ggtgaggtag
     9121 aagtggcctc cggggaagga acggaacgcc gtctccccgg tggtcagccg gtgccaggcc
     9181 agggctccgt cggtggggac gtgggggtcc gcgcttcctg tcagcacggt gatcgggcag
     9241 gagagcggcg cccccgggcg ccaggtgtag gtggcggcgg cccggtagtc gttgcggatc
     9301 gcgggcaggg ccagtcgcag gacttcctgg tcggccagca cccgggggtc ggtgccttgc
     9361 agttcggcga gcttggcgac cagtcggtcg tcactcagga ggtgcgcggt ggtccgatgg
     9421 gcgatggtcg gggcgacgcg gccggagacg aacaggtgcg ccaccctgct ttccggcgcc
     9481 tgttccgcga ggcggcgggc ggtctcgaat gccaccaacg accccaggct gtggccgaag
     9541 agcgccaccg gccggtccag ccagggtccg agcgccccgg cgatctgcgt caccaggctg
     9601 tcgacggtgt ccacgaacgg ctccaggcgc cggtcctgcc gcccgggata ctggacggcg
     9661 agcacctcga cccagtccgg cagcagatgg gtgaagggga ggaaggcgct ggcgctgccg
     9721 ccggcgtgcg gaaggcacac gagccgaagc gcggggtcgg cgacgggctg gtagcggcgc
     9781 agccagaggt cgcccgcgtc ggtggagccg ggcgcggtcg cggcggaccc tccgctcatg
     9841 cgtgatccgc ttccgggcgt cacggtttca gcgccttcca ccacgtgccg ttgtcccggt
     9901 accagtcgac ggtctccgcg agcccgcgct cgaaggcgac gcggggagcc catcccagct
     9961 cctcggtgat cttccgggtg tccacgcagt agcgacggtc gtgcgccgcc cggtccggca
    10021 ccctgtccac cacggaccag tcggcgccga agacgccgag aagacgacgg gtgaggtcga
    10081 cgttggacag ttccgtaccg ccaccgatgt tgtacacctc tccggccctt ccccggccgg
    10141 cgaccatggc gatgccccgg cagtggtcgt ccacgtgcag ccagtcgcgc cggtggaggc
    10201 cgtcgccgta caggggaagg tgcaggccct ccagcaagtg ggtcacgaag agcgggacga
    10261 ccttttcggg gtgctgatgg gggccgtagt tgttggagca gcgcgtcacc cggacgtcga
    10321 ggccgtgtgt gcggtggaag gcgagcgcca ggaggtcgga ggaggccttg gacgccgcgt
    10381 agggggagtt cgggtccagg gggtcggttt cggccgagga gccctcgggg accgaaccgt
    10441 acacctcgtc ggtggagacg tggacgaagc ggctcacgcc cgcctcaagc gccgaccgca
    10501 gcagtgtgtg cgtccccagc acgttggtgg tgatgaaggc ggctgagtcc gtgatcgagc
    10561 ggtccacgtg cgattcggcg gcgaaatgca ccaccaggtc gatgccgcgc agtgcctggg
    10621 tgaccgtggg ccggtcgcag atgtcgccgt gcaggaaggt gtgacggggg tggccggcga
    10681 cctcggcgag gttctcggtg ttcccggcgt acgtgagctt gtccagcgag aggacgtggg
    10741 cgtcggccag ctccggatag gagcccgaca ggagctgtct gacgaagtgc gagccgatga
    10801 agcccgccgc cccggtcacc aggacgcgca tccttgatct gcctttctgc cgtgctgtgt
    10861 gggggagggg tgatcaaccg gtgagcgtcg ccccgagtcc cgaggcgacc tccatgaggt
    10921 agcccccgta gctggaggcg ctcagctcct cacccagccg gtaacaggtg tccgcgtcga
    10981 tgaagcccat gcgcagtgcg atctcctcga cgcaggcgat gcgtacgccc tggcgctgtt
    11041 ccagcagctg gacgtactga cccgcctgga gcagggagtc gtgggtcccc atgtccagcc
    11101 aggcgaatcc acgaccgagc tgggtcagcc gcgcccggcc ctgctccaga taggagaggt
    11161 tgatgtccgt gatctccaac tcgttgcgag tggaaggctt gaggtccttc gccagctcca
    11221 ccacgtcgtt gtcgtagaag tacagcccgg tgaccgcgag gttggagcgg ggacggctcg
    11281 gtttctcctc cagcgacaac aggttcccct gctcgtcgat ctcggcgacg ccgtagcgat
    11341 cgggcgactt ggacggataa ccgaacagtt cgcatccgtc gagacgttgg agggagtgtt
    11401 tcaggacggt ggagaatccg gggccgtgga agacgttgtc gcccagaatg agcgccaccc
    11461 ggtcgttccc gatgtgtttg tcgccgacca ggaacgcgtc ggcgacaccg cgtggctcgt
    11521 cctggaccgc gtagtcgagg tggataccga ggcgtgagcc gtcgccgagc atgacctgga
    11581 acgtctccac gtgctggtgc gaggagatga tgaggatgtc ctggattccg gccagcatca
    11641 gtaccgacag cggatagtag atcatgggtt tgtcataaac gggcaactgc tgcttggaaa
    11701 gcgcaccggt cagcggctgc agtcgagtgg cgctgccccc agcgaggatt atccccctca
    11761 ccttggggcg tttcggcggt gtctcgaaca cggttggtcc tccggggcat gtattgccga
    11821 tatggggggt ggagacgctg tccgaaggga ccggccggac cggcgatcgc ctcgcggaca
    11881 cagcggcaga cagcattcac cccgacccgg gacccgtaat ccgaacacaa ggaatgcggt
    11941 gtcgtgaatg tcgaggatga ggagtgcctt tcggtctgcc gcgaggcggc gcggcgcttc
    12001 cgaaccgcgg gggattctca ggcggcggcg aggaaaggaa ccatggccgc gcctcctgcg
    12061 ccggaacggt ctccggtacg gccggccgtg ctcggacgcc ctatgcctcc gccttttgct
    12121 gttcctgcca cgcctgatag gtcggaagca atccaagacg ttcggcggtc gccagggtcg
    12181 gggcgttctt gtccctgtcg gagagcagcg gctcgatgtc ggccggccac acgattccga
    12241 ggtccgggtc gagcggattg acggagtgct cgcgttcggg agcgtacccg gaggagcaca
    12301 ggtagacgag agtggcgtcg tcggtgaggg agaggaaagc gcgacccagt cccgcggtca
    12361 gatagacggc ggtgttgcgt tccgcgtcca tgggcacgat ttcccagcgc ccgaaggtcg
    12421 gcgaaccgat gcggacgtcc acgatgacgt cgaggcccgc tccgcgcaca catacgctgt
    12481 atttggcctg accgggcggg atctcggtgt agtggatccc gcgcagcgcg ccgcggtggg
    12541 acaccgcgac attgacctgg gccaccggga aatcatgacc gaacgtctta cggaacctct
    12601 cgccccggaa ccactcgtgg gaccttccgc gatggtcgga gtggatgacg ggttcctgcg
    12661 accaggcccc ctcgatgctg agtggatgca tcgcgttctt tccttcggac cgattggttg
    12721 ggtacgggga gggccggggg gccacggccg agccgatcag ctggagcgtc tccagtagga
    12781 accctggcga tcgatctggt ggatctcgtc ggtgatgccg tgctcgtccc ggaactcgtg
    12841 gacggcctgc cggcacgccg gaatgcagta gtcgtcgacg atgacgtatc cgccgaccga
    12901 caccttgtga tagaggctcg tgagaacctc cctggtggct gcgtacgagt ccccgtcgag
    12961 cctcagcacc gcgagcttct cgatgggcgc ggtgggcatc gtgtccttga accagccggg
    13021 gaggaaccgg acctggtcgt ccaggagccc atagcgtgcg aagtttcttt tcacggtctc
    13081 cacatcgacc gggatgctga ggacttcgtt gtactggccg aggtcgatgt cgacgtccag
    13141 ctggtggtcg tcctcggtgg tcttggggaa accctggaag gagtccgcga cccacacctt
    13201 ccggtcccgc acgccgtgcg cctggaacac gccgcgggcg aagatgcacg ccccgccccg
    13261 ccagaccccg gtctccgcga agtcccccgg cacgccgtcg cgcagcacgt cctcaaggca
    13321 cttctgtagg ttgtcgagcc gcttgagacc gaccatcgtg tgcgcgacgt gcgggaagtc
    13381 ctcacccacc gcgcgcagct ccgcggaata cgaactgctc gtgatgaggc cggcgacatt
    13441 ggtctggtcc tcgtaaatca tattcgtcac gaccttcttc agaaggtcga gatacaggtc
    13501 tgcatcggca ggtatgactg tcattttcct cacttacggg tagcagtgcc cagcgggcgt
    13561 ctcgttcagg acgggggccg ccggggctga attacctgta tccacgctga tgaggtggac
    13621 gaggtggatg ggctagccat ctaacctcag tgatcagatt cgggcaaggg tcgaaaacca
    13681 gccacgtcgc gtatcgatcc tgtccggaag cgaggggcat atggtgcagt gacgactgcg
    13741 gccgatctgg ccgaaccttg ctgcggcgct aaccgtgtgc ttgcatgttg gacgtagatc
    13801 accttctccc gattgcattt agggtgagga aatccttgga atcttcaaaa gtcgttcaca
    13861 acaatcccac ggaaccaggc gtcgcatggc cagttgcgcg tacctgcccc tttaccctcc
    13921 ccgatcagta cgccgagaag cgtaaggacg agcccatatg ccgggctcag gtctgggacg
    13981 gctccagaac ctggctcatc accaagcacg agcacgtgcg agcccttctc gccgaccccc
    14041 ggatcaccat cgacccggcc aagctgccca agctctccgc ctccgacggc gacggcggcg
    14101 gtttccggtc gctgctgacc atggatccgc cggaccacag cgttctccgc cgcatgctca
    14161 tacccgagtt cagcgtgcgc cgggtccggg agatgcgccc gggcgtcgaa cgcacggtgc
    14221 acaggctgct ggacagaatc ctcgaacagc ggggaccggt ggacctggtg gccgaactcg
    14281 cgctgccgat gtccaccctg gtgatctgcc agctcctcgg cgtgccgtac gaagaccatg
    14341 agttcttcca ggagcgcagc gaacaggcca cgcgggtggg cgggaacgag gagtcactgg
    14401 ccgccctcct ggagctgcgt gactatctgg accggttggt caccgcaaag atcgagactc
    14461 cgggcgacga cctgttgtgc cggctcatcg ccgatcgact gcacaccggt gagatgcggc
    14521 acgccgagat cgtggacaac gccgtgctgt tgctcgccgc cggtcacgag accagtgcca
    14581 gcatggtggc actgagtgtc ctgacactgt tgcagcaccc cgacgcatca acgcagttgc
    14641 gtggcgacag tacgctgctg ccccaggcgg tcgacgagct cctgcgtttc cactccatcg
    14701 cggacggcct tcggcgggcg gtcacagagg acatcgagct cggcggcatc acgctgcgag
    14761 ccggggacgg tctcatcctc tcgctggctt ccgccaaccg cgacgagagc gccttcgcct
    14821 ccccggacga cttcgacctg cacggctcgg cacgccagca cgtcgccttc ggttacggcc
    14881 cgcaccagtg cctggggcag aacctggccc ggctggagct ggaggtcaca ctgggcgcgg
    14941 tggtggagcg cattcccaca ctcaggctgg ccggcgaagt cgacgcactg cgcgtcaagc
    15001 gcgactcgac gatcttcggg ctgcacgagc tgccggtcga gtggtgacgg aagggggata
    15061 cagcgtgcgg gtgacagtcg agcagagccg gtgcctggga gccggccagt gcgagcagtt
    15121 ggtaccggag gttttccgcc aggacgagga aggactgagc cgggtcctgg tcgccgagcc
    15181 cgagccggcg ttgtggccgc gggtgctcca gacggtgcaa ctctgccccg tacaggccgt
    15241 gatcgtccaa gaggctcctg gacgcgcgcc gcaggacacc gagtgactgc tgaccgctgg
    15301 gccggccgca cggtgctcgt cacgggtgca ctggggttca tcggctccca cttcgtccgg
    15361 cagctggacg cgcgcggagc cgaggtgctg gccctgtacc gcaccgaacg gcccgaaatc
    15421 caagccgagt tcgcggcact gaaccgggtc cgcttagtgc ggaccgagct gcgggacgag
    15481 tcggacgtgc ggggagcctt caagtacctg gcaccttcca tcgacaccgt cgtccactgc
    15541 gcggccatgg acggcaacgc acagttcaag ctggaacgct cggccgagat cctcgacagc
    15601 aaccagcgca ccatctccaa cctgctcaac tgcgtgcggg atttcggcgt gggcgaggtt
    15661 gtcgtcatga gctcctccga gctgtactcc gcctcgccca ccgtggcggc gcgcgaggag
    15721 gacgacttcc gcaggtccat gcggtacacg gacaacggct acgtcctgtc caagacctac
    15781 ggcgagatcc tggccaggct ccaccgcgag cagttcggca ccaacgtctt cctggtgcga
    15841 ccgggcaacg tctacgggcc gggggacgga ttcgaccgct cccggggccg ggtgatcccg
    15901 agcatgctgg ccaaggccga cgcgggcgag gagatcgaga tctgggggga cggcagccag
    15961 acccggtcct tcgtgcacgt cgccgacctg gtgcgggcct cgctgcgcct gctggagacc
    16021 ggaaagtacc cggagatgaa cgtggccggc gcggagcagg tctccatcct ggagctggcc
    16081 cggatggtga tggccgtcct gggacggccc gagcgcatcc gcctcgaccc cagccgcccg
    16141 gtcggcgccc cgagcagact tctggatctg tccagaatgt cagaagtgat cgacttcgat
    16201 ccccagcctc tgcgggccgg gctggaagag accgctcgct ggtaccgcct tcacaagcgc
    16261 tgaacccctc tttcacaccc ctggaaggta actcgtggtc aagcacgccc cgaactcgtt
    16321 gatccgagaa ataatccgag ccgccggcgg acatgacgcc gacctcaagg acctggccgc
    16381 ccggtacgct ccggccgaca tcgtccgtgt gctcctggac gagatcacca cgcgctgccc
    16441 ggctcccgtg aacgatgtcc ccgtcctcgt cgagctggcc gtccgggcgg gcgaccagct
    16501 gtttcccacc tacctgtacg tcctcaaggg cggcccggtg cgcctcgcca ccaaggacga
    16561 ggcgttcgtc gccatgcgtg tcgagtacga gctgggcgaa ctggcgcggg agctgttcgg
    16621 gccggtgcgg gagaacgtca ccggcgtgcg ccggaccacc ctcttcccgt acgtcaccga
    16681 cgcgcagtcg gaaggcgagg aggactcggg agccgaacac atcggcacgc acttcctggc
    16741 cgcgcagcag ggctcccaga ccgtgctggc cggctgccac tcccacaagc cggacctcag
    16801 tgaactctcc tcgcgttacc tgaccccgaa gtggggttcc ctgcactggt tcacccccca
    16861 ctacgaccgc cacttcagca gctaccgtga ccagcaggta cgcgttctgg agatcggcat
    16921 cggcggttac aagcaccccg agtggggcgg cggctcgttg cgcatgtgga agcacttctt
    16981 ccaccgcggt gagatctacg ggctggacat cgtcgacaag tcacacttcg acgcgccgcg
    17041 catcacgacc ctgcgcggcg accagagcga ccccgactac ctgcggtcga tcgccgagga
    17101 gtacggcccg ttcgacatcg tcatcgatga cggaagccac atcaacgacc acatccgtac
    17161 gtcgttccag gccctgttcc cgcacgtgcg gcccggcggc ctctatgtga tcgaggacct
    17221 gtggaccgcc tactggtccg gcttcggcgg caacgaggac ccgaagcagt acagcggcac
    17281 gagcctgggt ctgctcaagt ccctcgtgga ctcgatccag cacgaggaac tgccgcaggc
    17341 cggcggccac cgccccggct acgtcgacca gcacgtggtc ggcatgcacc tctaccacaa
    17401 cctggccttc atcgagaagg gcaccaacgc cgagggcggc atccccccgt ggatcccgcg
    17461 cgacttcgag acactggtcg ccgtctcttc ggggggacac gaatgagggg ccgtcggcac
    17521 cagccaccgg gacacacccg accggacggc gggaggccgg catgcgtgtg accctgctga
    17581 gcgtgggatc ccgaggtgac gtacagccgt tcgtcgccct ggggatcggt ctgaaggccc
    17641 gcggccacga cgtcaccctg gccgctcccg ccacgctgcg gccactggtc gagcgcgcgg
    17701 ggctgacgta caagctctcg cccggggacc ccgacgggtt cttccgcatg cccgaggtca
    17761 tcgaagcgct gcagcgcagt ccctcgttca agaacatgct cgcggggatg cccgaggcac
    17821 ccgagagcta cacgcagcag gtcgtcgacg cgatccacga cgctgccgag ggcgccgacc
    17881 tcatcgtgaa cgcgcccctc accctggccg ccgcgtacgg gcacccgccc gccccgtggg
    17941 cctcggtgtc ctggtggccc aacagcatga cctcggcctt cccggccgtc gagtccggac
    18001 agcgcagatt cggtccgctg acgcctctgt acaaccgcta cacccaccgc agggcggccc
    18061 gcgacgagtg ggagtggcgg cggcccgagg tcgacggcta ccggaagcga ctcggtctcc
    18121 gccccttcgg cgacgagtcc ccgttcctcc gactgggcca cgaccgcccg tacctgttcc
    18181 ccttcagccc cagtgtgctg cccaagccgc gggactggcc gcgtcagagc catgtcaccg
    18241 gctactggtt ctgggaccag cactgggagc cgcccgccga gctggaggcg ttcctggcgg
    18301 acggtgaacc cccggtggcg ctcaccttcg gcagcacctg gtcactccat cggcaggaag
    18361 aagccctcca ggccgccctc gacgccgtcc gcggcgtcgg acgccgactg gtcatggtcg
    18421 acgggccgga cggtgacctg cccgacgacg tgctccgcct gcaccaggtc gactacgcca
    18481 ccctgttccc caggatggcc gcggtgatcc accacggcgg cgccggcacg accgccgaag
    18541 tcgtgcgggc cggagtgcca caggtcatcg tgccggtctt cgccgatcac cccttctggg
    18601 cggcgcggct gtcccgagca ggcgtcgccg cccggccggt gcccttcacc cggttcagcc
    18661 gagaggcatt ggcacagagc gtccgtcagg cggtcaccga ccccgcgatg gcggcccggg
    18721 ccaggcggct gggtgaactg gtctccaagg aacggggagt ggacaccgcc tgcgacatcc
    18781 tcgagaagtg ggccgagaca gcacgggtcg cgccctgaga cggccaccgt cgggcgggtg
    18841 ggccggaacc cgctcgcccg ccggccgacg ggcccggggc ccgcgccgct acgccgagag
    18901 ccggtaggcg gagagccgca cggagagcgt gacctgggac ggcaccggca gccgctggat
    18961 catctcgtga tcccgctgca cgtcacggtg ccaggcattg ggccccatgc cgaccaggtg
    19021 ggccagagcc tggtggtcca gtgccatggt ccgggtcagc cgctccgtgg cgacggccga
    19081 gaagtgcggg gcgagttgct ccgcaagacg cgactccttg ccttcgtcca cctgcagcag
    19141 gccgagagtg ccgatgagtt cctgcaggtg atcgggcagg ggagtgacga ccaggaggac
    19201 gccacggtga tggaggatgc gatgcagttc aggaccgttg cgaggagcga acgtgttgat
    19261 caccacggcg gcggaggcgt cctgcagcgg aagcgtctgc caggcgtcgg tgacggcggc
    19321 cgcgatccgc ggatgggcct tcgcggcacg tcgcaccgcg tatttggaga tgtccagcag
    19381 cagtccgtcg acatcaggga acgcgtccac gaccttggcg tggtagtggc ccgttccgcc
    19441 accgatgtcg acgatgcaac cgggcacggc tggatcagcc gtccgccgcg ccagatcgac
    19501 aagcgcgtcc atcacagggc cgtagtgacc cgccgacagg aatgcgtccc gggcctccac
    19561 catttccttt gtgtccgctc gcagcttcgt cgccccggga agcagattca cataaccctg
    19621 cttcgcgatg tcgaaggagt gtccggcggg gcaggaaagt gcacggtctc ccagcgccag
    19681 cgaagcgccg cagtgcgggc aggcgaggta tcgcacgatc ctgttgagca tggggcaccg
    19741 ttccttcggg cgagtcggcg gaccggccaa ccttaacgca ggcatccggg ccgccggccg
    19801 cccggtgcag tgccgaagaa tccccgtgac gcgcacccac ggcaactgaa ccccaattgc
    19861 gcgcacgaca cgacaaccgg ccaattcccc ggcaattcct tatggaatgc cgcgcatacg
    19921 gcctcaccca tttcagcaag tgctgacagt cgccctgcac tgtcagcgtg acaaccccta
    19981 tcgatcgatc aggagttccg atggccccca agaatggtgc gcagcgttcg agcgacatag
    20041 ccgtcgtcgg catgtcctgc cgccttccgg gggcgcctgg catcgatgag ttctgggaac
    20101 tgctgacctc cggaggcagc gcgatcgagc gtcgcgccga cggcacctgg cgaggctccc
    20161 tggagggggc cgccgagttc gacgccgcct tcttcggcat gtccccccgc caggccgccg
    20221 ccgcagatcc gcagcagcgg ctcatgctgg aactcggctg gaccgccctg gaggacgccg
    20281 ggatcgtccc gggcagcctc gccggcacgg acaccggcgt cttcgtgggt atcgccgccg
    20341 acgactacgc ggcactcctg caccggtcgg agacccccgt cagcggccac accgctaccg
    20401 gcctgagccg gggtatggcc gccaaccgcc tctcctacct cctgggcctg cgcggtccca
    20461 gcctcgcggt ggacagcgcg cagtcctcct cgctggtcgc ggtccacctg gcctgcgaga
    20521 gcctgcgccg cggcgagtcc gacctcgcga tcgtcggcgg cgtcagcctg atcctcgccg
    20581 agaacagcac ggcaggcatg gagctcatgg gcgcgctctc gccggatggc cgctgctaca
    20641 ccttcgacgc tcgcgccaac ggctacgtac ggggtgaggg cggagcctgc gtcgtcctca
    20701 agcctctgga ccgggcactg gccgacgggg accgcgtcca ctgtgtcatc cgaggcagcg
    20761 cagtcaacaa cgacggcggc ggctccaccc tgaccacacc ccaccgcgag gcccaggaag
    20821 ccgtgctgcg cgcggcgtac gaacggtccg gggtcggccc ggaccaggtg tcctacgttg
    20881 aactgcacgg cacgggaacg cctgtcggcg accccatcga ggcggcggct ctcggcgcgg
    20941 tgctcggcac ggcccggggc cggagcacac cgctgtccgt ggggtcggcc aagacgaacg
    21001 tcggccacct ggaagcggct gcgggtctcg tgggattcgt gaaggccgcc ctgtgtgtcc
    21061 gtgagggcgt ggtaccgccg agcctgaacc acgcgacgcc caaccccgcc atccccatgg
    21121 accggctcaa cctgcgcgta cccactcgac tggacacctg gccgcagccg gacgagcagg
    21181 caaccggccg gctgcgactg gccggcgtct cgtccttcgg catgggtggg acgaatgcgc
    21241 atgtggtggt ggaggaggcg cctgttccgg aggaggggga gttcgtcggg gatgcgccgt
    21301 tggctgtggt gccggtggtg gtgtcgggtc gttcggcggg tgtggtggct gagctggcgt
    21361 cccgtatggg ggaggtggct gggtctggtc ggttggtgga tgtggggttg tcgtcggtgg
    21421 tgtcgcggtc ggtgttcgag caccggtccg tggtcctggc cgaggactct gtggacctga
    21481 gtgccggttt ggatgctgtg gccgctggtg acgggctgtc gcctggtgtg gtgtcgggtg
    21541 tggtgtcggt cgagggtgcc cggtcggtgt tcgtgttccc tggtgcgggg gcgaagtggt
    21601 cggggatggc ggcgcggctg tgggctgagt cggttgtgtt cgcggagtcg atggcgcggt
    21661 gtgaggcggc gttcgagggc ttggtggact ggcggttgtc ggatgtgatc gctcaggtgc
    21721 cgggtgctgt gtcgttggag cgtgaggatg tggcgcagcc ggcctcgttt gcggtgatgg
    21781 tgtcgctggc ggcgttgtgg cggtcgctgg gtgtggtgcc ggatgcggtg gtcgggcatt
    21841 cgcaggggga gatcgctgcg gcggtggtgg cgggtggcct gtcgttggag gacggggcgc
    21901 gggcggtggt gttccggtcg cgggtggcgg aagaggtttt gtcgggaggg gggattgctt
    21961 cggtgcgtct ttcgcgggcc gaggtggagg agcggttggc gggtgggggt ggtgggctga
    22021 gtgtggcggt ggtgaatgcg ccgtcgtcga cggtggtggc tggtgagctg ggagagttgg
    22081 agcggttcgt tgccgcgtgt gaggcggagg gggtgcgggc gcgtcggctg gagttcgggt
    22141 atgcgtcgca ttcggtgttc gtggagccgg cgcgtgggcg gttgctggag gcgctggccg
    22201 acgtccgtcc ggtgagcggc gagatcccgt tctactcgac ggtggaagcc ggcgtcgtgg
    22261 acacggcgtc gttggatgcg gagtactggt tcgggaatct gcgtcggccg gtgcggttcc
    22321 aggagacggt cgagcagctg ctcgcggacg gtttccgggt gttcgtggag tgcggtgcac
    22381 atccggtgct gaccggggcg gtgcaggaga cggcggagtc cgtgggccgg caggtgtgtg
    22441 cggtgggttc gctgcgccgt gaggacgggg gtctgcgtcg tttcctgacc tcggtggcgg
    22501 aggcgttcgt ccagggtgtc gacgtcacct ggcccgccct cttcgccgac accggcgccc
    22561 gtaccgtcga cctgcccacc taccccttcc aacgccagca ctactgggca caggcttcac
    22621 ccgccggcac cggcagttcc gctgcggccc gcttcggcat gacctgggag gagcacccgc
    22681 tcctcagcgg cgcgctgccg ctcgcggagt ccggtgagct gctgctcgtc gggcggatct
    22741 ccccggcctc tcactcctgg atcgccgacc acaccgtggc cgggaccgcc ctgctgcccg
    22801 ggacagcctt cgtcggcatg gcgctgcatg ccgccgcggt cgtgggctgc gcgggcgtgg
    22861 aggagctgag catcgaggcc ccgctgccgg tgcacggtgg catccggctc caggtggtga
    22921 tcgacgagcc cgactcctcc gaccggcgcc gcgtgagcgt gttcgcgcgg ccggaggcgg
    22981 aagacgggga caccggtcgg tggacccgac acgccaccgg cgtactgacc cctgccgccg
    23041 cccccgaccc gggccggccg cagtggagcc gcgaggcctg gccgccgagc ggttccgtcc
    23101 gcgcggaggc ggcggagctc tacgaccggt tctccgcgct gggatacgag tacggcgagg
    23161 tgttcgccgg ggtcgaggcc gtctggctgc gcgagggcga ggtgttcgcc gaggtccgcc
    23221 tgcccgcggg cgcggcgccg gacgccgagc ggttcggggt gcaccccggc ctcctcgacg
    23281 cggctctgca gccctggctg ctgggcgact tcctgtcgcg gcccgacgac ggatccgtgc
    23341 tgctgccgtt cgcgtggcgc ggcatcacgc tgcacgcgac cggtgcagac gcgctgcggg
    23401 tccgcctggg cccggccgga gaaggggcca tgtcgctcga agccgtcgac ctcgccggtg
    23461 ccccggtgct gtcgatggac gcgctggtgc tgcgtccgct cgcgcaggac cggctggtgg
    23521 aactggtcgg cggcacgacg tccgcgccgc tgtaccgcgt ggactggcag cggagcccga
    23581 tcgcgaacac ggcgccgtcg gccacggggc tcttcggctc cttcccgtcc ggtgccacgc
    23641 gccggtgggc ggtcgtcggg cagggcggtg ccgccgcacg gtacgcgacg gcggaccccg
    23701 gcacggggtg cgtcggggtc ttccccgacc tggacgcact gcgtacggcg ctggactccg
    23761 gagcggaccg ccccgacatc gtcctcgccg acttcggggc ccggcccggc accgccgccc
    23821 cgcacgggac ggctctggcc gacggggtac gggacacggc tcggcggggg ctcgccctcg
    23881 tacagggctg gctgtccgac gagcgcttcg ccgccgcacg cctcgccgtg ctcaccgagc
    23941 acgccgtcgc caccgaggcg gacgagcggc aggtggacct cgccggatcg gcgctgtggg
    24001 ggctgatgcg ttcggcgcag accgagcacc ccgaccgctt cgtcctcgtc gaacacgacg
    24061 ggcaggacgc ctcgtaccag gcgctgcccg ccgctctcga cagcggaatt ccccaactgg
    24121 cccttcgctc gggcaaggta cgcacgcccg ggctggccgt cctgcccacc ccgggagacg
    24181 ggcccaccgc gacgggcacg gggttcgatc ccgagggcac cgtgctcgtc accggcgcca
    24241 ccggcaccct cggcagcctg ctggcccggc acctggtcac cgcacacggc gtacggcatc
    24301 tgctgctgct cagccgcagc gggcgcgacg ccggcagggc cgcggaactg gagcgtgaac
    24361 tcaccggtct cggcgccgag ttccagctcc tctcctgtga tgcgacggac cgggtagcgc
    24421 tgcgggaggc cctcgccacc gtccccgccg cacacccgct gaccgcggtg atccacacgg
    24481 ccggcgtcct ggacgacggc gtcgtcgagg cgctgacccc cgaacggctg gaccgcgtgc
    24541 tgcgccccaa gacggacgcc gcactgaacc tgcacgagct gaccgcggga atgccgctga
    24601 aggcgttcgt cctgtactcc ggggcggtcg gcctgctggg cggggccgga caggccaact
    24661 acgccgcggc caacgcgttc ctggacggcc tggctcagta ccggcacgcg caggggctgc
    24721 ccgcggtgtc cctggcatgg ggactgtgga gcgccgccag cacgttcacc ggccatctcg
    24781 gcgaggtgga tctgcgccgc atggagcggt ccggcatcgc gccgctcacg aatgagcagg
    24841 gtctcgaact gctcgaccgg gcacttggtg ccgccgcggg cgcggacgcg ccgcagatct
    24901 gtgcgatgcg gctggacacg gcggcactgc gtcggcaggc ctccgaacac gggcccgctt
    24961 cggtgcccct gctgctgcgt acgctggcgg cgcccgccgt acggatcggc gcggcgcgaa
    25021 cgggccgtgg cgcacgggcg gcgtccgcgg tcacggacgt accgagccgg gcgcaagact
    25081 tgcgcgaacg actggccggg ctggacgcgg cgggaaggcg ggacgaactc ctggccgtgg
    25141 cccaggcgca gttggccgat gtgctgggct tcaccgacaa gaccgcggtc gaccccgttc
    25201 gctccttccg cgagatcggt ctggactcgc tgaccgccgt cgagctgcgc aacaggctcg
    25261 atgccgtcac cggactgcgg ttgtcgtcgg cgctggtctt cgaccacccc aacctcgacg
    25321 cgctcgccgg ccacttggcg gagctcctca tggcggaggg caaggacgac gcgggcgctg
    25381 cggcgctgtc gggcgtcgat gccctggacc gggcggtccg gggcatggcg gccgacgaca
    25441 cgcggcgtga cgccgtccgc cgacgtctca cagaactgct ggcggtggtc ggcgatgccc
    25501 cacgggacgg cgaccgcagc acacgaacgg ccgccggcac aggaagccac ggcgtgcagg
    25561 cgggccccga cctgctgggg cagctggact ccgcctccga cgacgacctg ttcgccttca
    25621 tcgaagacca gttgtgagcg ggacgccgtg cgcgttcccc acccgtaccg aagcgcgccg
    25681 cagcaggcgc gccttgcacc gacacgagca cgtaggccag gagggtccgg cagatgacgg
    25741 ccaacgacga caagatccgt gactacctga agcgggttgt cgccgaactg cacagcacgc
    25801 gccagcggct gaacgcgctg gaggacaacg cccgcgagcc catcgccatc gtggggatga
    25861 gctgccggct gcccggcggg gtgaccaccc ccgagagtct gtgggaactg gtcgactccg
    25921 gcaccgatgc ggtctcgccg ttccccgacg accggggctg ggacctggac gcgctgcacc
    25981 acccggagtc gggagccgtc cactcccgcg agggcggttt cctccacgac agcgccgact
    26041 tcgacgcgga gttcttcggc atcagcccgc gagaggccct ggccatggac ccgcagcagc
    26101 ggctcctgct ggagaccgcc tgggaggtgt tcgagcgggc cggtatcgac ccggcctccg
    26161 tccgcggctc gcgcacgggg gtgtacgcgg gtgtcatgta ccacgactac ggcgcccggc
    26221 tgaacgagat cccgccgggt ctcgagggct acctggtcaa cggcagcgcg ggcagcatcg
    26281 cctccggccg ggtggcctac accctcgggc tggagggtcc cgccatcacc gtcgacacgg
    26341 cctgctcctc gtcactggtc gccgtgcacc tggcggcgca ggcgctgcgg cagcgggagt
    26401 gcgacatggc gctcgcgggc ggcgcgaccg tcctgtccac ccccgacctg ttcaccgact
    26461 tcgcgcgact gggcggcctg gcctccgacg ggcgctgcaa ggcgttctcc gacgcggccg
    26521 acggcaccag cttcgccgag ggtgccggaa tgctgctcct gatgcgcctg tcggacgcgg
    26581 tggacaaggg ccacaccgta ctggcggtca tccgcggctc cgccgtcaat caggacggtg
    26641 ccagcaacgg cctgacggcc cccaacggcc tcgcccagca gcgggtgatc cgcgaggcgc
    26701 tcgccaacgc ggacctgggc cccgaccaga tcgacgcggt ggaggcacac ggcaccggaa
    26761 cccggctcgg cgaccccatc gaggcacagg ccctgctgca cacgtacggc acgagccgca
    26821 gccccgaacg gccgctgctg ctcggctcgc tgaagtccaa catcggccac acccaggccg
    26881 ccgccggcgt ggccggaatc atcaagacgg tgctggcgat gcgccacggc cggctgcccc
    26941 gcaccctgca cgtcacccgt ccctccagcc gggtggactg gtcggcgggc gcggtggaac
    27001 tgctcacgca gacacaggac tggcccggcc agggggacgc cccgcgccgc gccggcgtgt
    27061 cctccttcgg cgccagcggc accaacgcac acctcatcct ggagggcgtc ccggacagcg
    27121 acgacacggc ggcggagcgc gaaccgtccg ccggcggtgg cgcctggctg ctctcgggcc
    27181 ggaccgaagc ggcgctgcga gcccaggccc gcagactcca cggccatctc gccgcccgcc
    27241 cccacgtgtc acccgccgcg gtcggacgga cgctggcccg ctcccgtaca gcgttcgagc
    27301 accgggccgt cgtcatcgga caggacaccg ccgcactcct gagcggcctc agggagctgg
    27361 cgtccggcgc cgcgcacgga cccggggtga tcaccggccg ggccgcgcgc ggacgccgta
    27421 ccgcactgct cttcaccggg cagggcagcc agcggccggg cgccgggcgc cggctctacg
    27481 agcggtacga ggtgttcgcc cgggccctgg acgagacggc cgcggaactc gaccggcacc
    27541 tggaccgccc gctgcgcgag gtgatgttcg cggaaccggg cagcgcgacg gccggcctcc
    27601 tcgaccgaac cgagtacacc cagcccgcgc tgttcgccct ggaagtcgcc ctcttcgagc
    27661 tggtgagcgc ctggggcctg cgccccgacg cactcctggg gcactcggtc ggcgaactgg
    27721 ccgccgccca cgttgccgga gtgttcaccc tgcccgacgc cgcccgcctg gtgacggcgc
    27781 gggggcggct gatgggcgag ctgccggccg gtggcgccat ggcggcgatc caggcaggtg
    27841 gcccggagat cgaggagacg atcacggcgc tcacggctcg taggcaggcg cgcatcgccg
    27901 tcgccgcact caacgggccc gacgccaccg tgatctcggg cgacgaggac gcggtcgccg
    27961 agctcgccgc actgtggcgg gagcggggcc gccgtgccaa ggtgctgccc gtcagccacg
    28021 cgttccactc gccgcgcatg gacgccgcac tggaaccgtt cgcccggatc gcgcgcgacg
    28081 tctcctacgc cgagccgcgc atcccggtgg tctccaacct gaccggcgag gtcgcgtcgg
    28141 ccgcgacgct gtgcaccccg gagtactggg tgcgccacgc gcgcgaggcc gtgcgcttca
    28201 gcgacggctt ccgcaccctg cgcgaccagg ggatcgacac cttcgtcgaa ctgggaccgg
    28261 acggcgtgct gtccgccctg ggacgtgact gcctgcgcga agaggaacag gacgccccgc
    28321 accaggacgg ctcgacggac cgtgacacgg ccggttcccc cgccgacggg caggagcgtc
    28381 ccgtgctgac ggtgccgctg ctgcgccggg accgcgacga gacgaccacc tgcctcgggg
    28441 ccctggccgc cgtccacacc cacggtgtcc ccctcgacct cgcggccgtg cacggtgacg
    28501 ggcccgccgt cgacctcccc acctacgcct tccagcgcac gcgctactgg ctggacgtcc
    28561 cggcccccgc cgccggcctc accaccaccg gtctggaggc agcggaccag cccctgctcc
    28621 cggccgccat cgacctgccc gacggggaag gcaccgtacg gaccgggctg ctctccgtcc
    28681 gcacccaccc gtggatcgcc gaccaccgcg tccagaaccg caccgtggta cccggagcgg
    28741 ccctcctgga catcgccgcc tgggcgggca ccgaagcggg ctgcccccgg gtcgccgagc
    28801 tgaccttcgc cacgcccctc gtactgcccg agagcgggga gggggtccgg ctgcgcgtga
    28861 cgctgagcgg tcccgacgcg gaaggcatcc gtacgatacg catcgactcc cggcccgccg
    28921 acgccgctcg ggcagccgac gccccctccg actggacccg gcacgcgtcc ggcaccctca
    28981 cccccggaac cgaggaggct ggtgacggcg ccgacgtgcc ggcggacctg ctcggcgtct
    29041 ggcccccggc cgacgcgacc ccggtggccc tcgacgcgga cgccgtcgcg gctgagtacc
    29101 ggcgcctcgc ggacgcgggc gtgacgtacg gccccgtgtt ccggggactg cgcgccgtct
    29161 ggcggcgcgg cgaagagatc ttcgccgagg tccggctccc cggccaggcg gccgccgacg
    29221 ccccgcggta cggcatgcac ccggccctgc tggacgctct ggcgcacgcc accggattcg
    29281 gcgaacagtt caccgaggcc cacggcctgc tgccgttctc ctggagcgac gtccggatcc
    29341 acgtccgcgg caccgactcc ctgcgcgtac ggatcgcccc ggcgggaccc gacgccgtga
    29401 ccgtcgcggc ggccgacccg gcggggcgcc cggccctcac cgcccgctca ctcacgctgc
    29461 gccccgtccc ggcgcaccgg ttcccgagtc cgcaggagcg gagcacaccg ttgtaccgac
    29521 tggagtggac gtcggcctcc gctccggtga ccggacacgc ccgtcccagg ccggcggcag
    29581 cggagtgggg cgtcctcggc gatgcgggcc cggccctcct cgagggcgta cgcgacggag
    29641 cgcaggcacc ggtacggacc tacgacgatc tggccgcgct cgcggcctcc gacacgcccc
    29701 tgcccgacca cgtcctggtg gagctcggcc acgacggaga cgaccttgcc gcaggcgccc
    29761 acgacctggc cgaacgtgcg ttggccgtgg tgcagggctg gctggcccac gcccgcttca
    29821 ccgacgcacg actggtcgtg ctgacacacg gggcggtggc ggccggcacc agcgcggtcc
    29881 gcccggcctc ggccgtcgcc tggggactgc tgcgcagcgc acagtccgag cacccgggcc
    29941 gcttcgtact ggtcgacgcg gacccctccg acccggctgc ctcgtaccgc tccctgtcgc
    30001 gggccgtcac ctcgggagcc tcccaactcg ccctgcgcgg cgacgagatc ctcgtacccc
    30061 gactcaccca tggagcgaac gggcagggcg ctgccgccgg tcccctcggc gacgccaccg
    30121 agccggaagc ggccgcggcc atggggtccg ccccgtcggg gagcccttcc ggcccctggc
    30181 gcgcggacgg caccgtgctc gtcacgggcg gaaccggaac gctcggcaag gccgtggccc
    30241 ggcatctcgt gaccaagcac ggcgtccggc acctgatact ggccggccgg cgcggcgcgg
    30301 acgccccggg cgcggccgga ctggccgccg aactgaccga cctgggcgcc gtcgtgaaca
    30361 tcgtccgctg tgacgccgcc gaccgctcgg cgctcgaagg cctgctggcc gccgtccccg
    30421 ccgcccaccc gctcaccgct gtcgtgcaca ccgccggtgt gctggacgac ggcattgtca
    30481 cggcacagac cctccaacgg gtctcggcag tgctgcgggc caaggcggac gcggtcacac
    30541 acctgcacga actgaccagt gacctggacc tgtccgcctt cgtcctcttc tcgtcggctg
    30601 cgggaaccct cggcagtccc ggccagtccg gctacgcggc cgccaacagc ttcctcgacg
    30661 cgttcgccgc ctggcggcgc gcgcagggcc tgcccgccgt gtccctggcc tggggcctgt
    30721 ggggcgacgg cggtgacggc gacggcggta gcgcaggggc cgacggcatg ggagcgagcc
    30781 tggccgccgc cgacctggca cggctgcgcc gttccggaat cctgcccctc gaccccgccg
    30841 aggcactgga actgttcgac gaggcctgcg ccccctccag gaccgaggca gtgctgctgc
    30901 cgatccgcct cgacctggcc ggcctgcgtg ctcgtgccgc ccgcggcacc gtacacgcag
    30961 gcgtggtacc cgaagtgctg cacgccctgg tgcccccgcc cgccggtgcc ggaccctcgt
    31021 ccggtgcggg cacgccggac cctgcggcgg gccaggagcc cccgaccacg gccgcggcat
    31081 ccggcaccct ggccgaacag ctcgccggga agccgcgcgg cgagcggctc gccgtcctca
    31141 gggagctcgt gcgcaccgaa atcgcctcgg tgctcgggca cgcggacgcc caacgcgtcc
    31201 aactccagtt ctccttcaag gaagccggat tcgactcgct caccgccgtc gaactccgca
    31261 acaggctcac ggccgtcacc ggaacgaggc ttcccgccac actggtcttc gaccatccga
    31321 cgccggcggc actcgtcgac cacctggaac aggaactgcc gaagggcggt cagaaacttc
    31381 ccgcggacgt cccggccgtt ctggaggcac tcgatcggat ccgggacgga ctggccaccg
    31441 ctgtcaccga cgacaacggc cgcgcccacg tcgcggaacg ccttcaggaa ctgctcggca
    31501 cgctcgcccc gccggtggcg ggcgtccgcc cggtcaacgg ctcgaacggt cacgacgggc
    31561 agggccccga tgaactgtcg gtcggcgaac gcctcgccgc cagctccgac gacgagctct
    31621 tcgacctctt cgacagcgac ttccgatcga tgtagcccag ggcccgcctg ccgccacggc
    31681 tctcccgccc cgccgcccgt cccacacccc tggagaacag caccgtgtct tccgcaacgc
    31741 ctgccaccaa cgaagaaaag ctccgcgact atctccgccg cgccatggcc gacctgcacg
    31801 aggcccgcga gcagatcagc cggaccgagt ccgccaggca tgagccgatt gcgatcgtgg
    31861 ggatggggtg ccggctcccg ggtggggtgt cgtcgccgga ggggttgtgg gatctggtgg
    31921 cgtcgggggt ggacgcggtc tctccgttcc ctaccgatcg gggttgggat gtggcgggtc
    31981 tgtttgatcc ggagcctggt gtgcctgggc gtacgtatgt gcgtgagggt gggttcctgc
    32041 atggggcggg ggagttcgac gcggggtttt tcggtatttc gccgcgtgag gcgttggcga
    32101 tggatccgca gcagcggttg ttgctggaga cgtcgtggga ggcgttggag cgggcgggta
    32161 tcgatccgca ttcgctgcgc ggctcacgga ccggcgtcta cgcgggagtg atgtaccacg
    32221 actacggcag caccgtggcg ggctccgccg ctcccgacga cgagacggcc ggcttcctcg
    32281 gcatcgggac gtccggcagt gtcgcttcgg gtcgtatctc gtatgtgctg ggtctggagg
    32341 ggccggcggt gacggtggat acggcgtgtt cgtcgtcgtt ggtcgcgttg catctggcgg
    32401 tgcgggcttt gcgcagtggt gagtgtgatc tcgcgctggc gggtggggtg acggtcatgg
    32461 cggagccggg tgtgttcgtg gagttctcgc ggcagcgggg tctggccgcc gatgggcggt
    32521 gcaaggcgtt ctcggactcg gccgacggca cgggctgggc cgagggcgtg ggtgtgctgg
    32581 cggtggagcg gttgtcggat gcggtgcgtc atgggcgtcg ggtgttggcg gtggtgcgtg
    32641 gttcggcggt gaatcaggac ggtgcgagta atgggttgac ggcgccgaat ggtccgtcgc
    32701 agcagcgggt gatccggcag gcgttggcgg atgcgcggtt gggtgtgggt gatgtggatg
    32761 tggtggaggc gcatgggacg gggacgcgtc tgggtgatcc gatcgaggcg caggcgttgt
    32821 tggcgacgta tgggcagcgg gacgcggggc ggcctttgtg gcttggttcg ctgaagtcga
    32881 atgtgggtca tacgcaggct gctgcgggtg tggccggtgt gatcaagatg gtgatggcga
    32941 tgcgggacgg agtcctgccg aagacgctgc atgtggatga gccgtcggcg gaggtggact
    33001 ggtcggcggg ggcggtgtcc ttgctgacgg agcaggagcc gtggcctgag gtggggcgtc
    33061 cgcgcagggc cgcggtgtcc tccttcgggc tcagtgggac gaatgcgcat gtggtggtgg
    33121 aggaggcgcc cgctccggag gtcggggagg tcggggttgg tgtgtctccg gctgtggtgc
    33181 cggtggtggt gtcgggtcgt tctgcgggtg tggtgcgtga gttggcgtcc cgtatggggg
    33241 agatcgctgg gtctggtcgg ttggtggatg tggggttgtc gtcggtggtg tcgcggtcgg
    33301 tgttcgagca ccggtccgtg gtcctggccg aggactccgc ggagctgaac accggtctgg
    33361 acgccctggc tgctggtgtg ccgtcgtctg gtgtggtgtc gggtgtggtg tcgggggagg
    33421 gtggccggtc ggtgttcgtg ttcccgggtc aggggacgca gtgggtgggt atggcggttc
    33481 ggttgtgggc tgagtcgggt gtgttcgcgg agtcgatggc gcggtgtgag gcggc
//
