LOCUS       NZ_BMVE01000002        32734 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces goshikiensis strain JCM 4640 sequence02, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVE01000002
VERSION     NZ_BMVE01000002.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1126124)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650555.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:30:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,491
            CDSs (total)                      :: 7,410
            Genes (coding)                    :: 7,286
            CDSs (with protein)               :: 7,286
            Genes (RNA)                       :: 81
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 44 of 125
            Pseudo Genes (incomplete)         :: 101 of 125
            Pseudo Genes (internal stop)      :: 9 of 125
            Pseudo Genes (multiple problems)  :: 27 of 125
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 49478
            Orig. end                         :: 82212
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVE01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32734
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..32734
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32734
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:18734](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..18734
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            444..1151
                     /locus_tag="IE248_RS05730"
                     /old_locus_tag="GCM10010336_11610"
     CDS             444..1151
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520784.1"
                     /locus_tag="IE248_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11610"
                     /product="class III extradiol dioxygenase subunit B-like
                     domain-containing protein"
                     /protein_id="WP_190030099.1"
                     /transl_table=11
                     /translation="MLVAAAVCPAPPLLVPEVAAGAAAELADARTACSDALAVLAAARP
                     DRLVVVGAAGADHTGPYPQGSRGSFRGFGVAADVRLGEGEEGPRVLPTSLAVAAWLLAR
                     ARWGAAPVEGLGVAEPLEADACLRTGRELAVTDDRVALLVMGDGSACRTVKAPGYLDER
                     ATAFDAEAARALGAADTAALAALDPGLARELKAAGRAPWQVLAGAAEGAGLDGRLLYDE
                     APYGVGYFVATWS"
     gene            complement(1273..1518)
                     /locus_tag="IE248_RS05735"
                     /old_locus_tag="GCM10010336_11620"
     CDS             complement(1273..1518)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742934.1"
                     /locus_tag="IE248_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11620"
                     /product="antitoxin"
                     /protein_id="WP_008742934.1"
                     /transl_table=11
                     /translation="MGLLDNLKAKLAPAKDKVGDLAQQHEGRIGQNLDKVAQVVDSKTK
                     GKYHGRIETGTSKAKDALGKIAHKDGPGGQTPPAAS"
     gene            complement(1542..1748)
                     /locus_tag="IE248_RS05740"
                     /old_locus_tag="GCM10010336_11630"
     CDS             complement(1542..1748)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657429.1"
                     /locus_tag="IE248_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11630"
                     /product="hypothetical protein"
                     /protein_id="WP_073796341.1"
                     /transl_table=11
                     /translation="MGVFGRFFGRKNQASTEEVAAGDLTAASEGAEAGTAEEGAPAAEA
                     VEIPKQQSAEAAADSETGEGART"
     misc_feature    complement(1930..1946)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            1957..2895
                     /gene="miaA"
                     /locus_tag="IE248_RS05745"
                     /old_locus_tag="GCM10010336_11640"
     CDS             1957..2895
                     /EC_number="2.5.1.75"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="miaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IPPT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034825.1"
                     /locus_tag="IE248_RS05745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11640"
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="WP_073796342.1"
                     /sec_met_domain="IPPT (E-value: 6.5e-83, bitscore: 273.9,
                     seeds: 863, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKAAPAPRVIAVVGPTAAGKSDLGVALARHFDGEVVNADSMQLY
                     RGMDIGTAKLTVEERGGVPHHLLDVWEVTETANVAEYQRLARVEIDKLLAEGRTPVLVG
                     GSGLYVRGALDAMEFPGTDPEVRARLEEEVTLRGPGALHARLAAADPAAAAAILPSNGR
                     RIVRALEVIEITGRPFTANLPGHESVYDTVQIGVDVGRPELDERIARRVDRMWEDGLVD
                     EVRALEARGLRDGITASRALGYQQVLSALAGECTEEEAKAETVRATKRFARRQDSWFRR
                     DPRVHWLSGAVVDRGELPGLAQSLVERAVTA"
     gene            3007..3558
                     /locus_tag="IE248_RS05750"
                     /old_locus_tag="GCM10010336_11650"
     CDS             3007..3558
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742937.1"
                     /locus_tag="IE248_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11650"
                     /product="hypothetical protein"
                     /protein_id="WP_190030457.1"
                     /transl_table=11
                     /translation="MEAGPRNTGQDETRRETDPVRLDGSEGPVEPDGAVGALAGPDTLG
                     LPAEPARLSPDGPDAPDPAEVEAASGPEFEVELRPQRRLRIWQIAPIVLLALAGSLMFA
                     FPLAFEFGDGGAVVAMLGFLISSCAGGWGMMAARRVGYSWPGLPPRGSGRRPDWRMAAL
                     YALAALAVVALAVYRVARLR"
     gene            3637..4512
                     /gene="dapF"
                     /locus_tag="IE248_RS05755"
                     /old_locus_tag="GCM10010336_11660"
     CDS             3637..4512
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742938.1"
                     /locus_tag="IE248_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11660"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_073796344.1"
                     /transl_table=11
                     /translation="MTQTSLSFLKGHGTENDFVIVPDPDNAIELPATAVAKLCDRRAGI
                     GGDGVLHVVRSAAHPEAKAMAGEAEWFMDYRNSDGSIAEMCGNGVRVFARYLQYAGHVE
                     PGDLAIATRGGVKRVHLDKRGDVTVSMGRAEFPEGEVTVSVGDRSWPARNVNMGNPHAV
                     AFVDSLDDAGTLYDAPPFSPASAYPAGVNVEFVADRGPRHVAMRVHERGSGETRSCGTG
                     ACAVAVAAIRRDGVDPAETGEQVTYTVDLPGGTLVITEYPDGRIDMTGPAVIVGSGEFD
                     ATWLAETAFV"
     misc_feature    4528..4543
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    4538..4551
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            4653..6791
                     /locus_tag="IE248_RS05760"
                     /old_locus_tag="GCM10010336_11670"
     CDS             4653..6791
                     /EC_number="2.7.6.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888373.1"
                     /locus_tag="IE248_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11670"
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="WP_190030100.1"
                     /transl_table=11
                     /translation="MSAEATNPEARSEARPELRRRGRTRLDLRRLGRAALLGPTSRDRL
                     PDAIGHVAEAHRAHHPDADLSILRRAYVLAESSHRGQMRKSGEPYITHPLAVTLILAEL
                     GAETTTLTASLLHDTVEDTEVTLDQVREEFGDEVCFIVDGVTKVEKIDYGAAAEPETFR
                     KMLVATGNDVRVMSIKLADRLHNMRTLGVMRPDKQARIAKVTRDVLIPLAERLGVQALK
                     TELEDLVFAILHPEEYEHTRALIAAHAGERDPLPAIAESVRVVLREAGIHAEVLVRPRH
                     FVSVHRISRKRGELRGSDFGRLLILVGENADCYGVLGELHTCFTPVVSEFKDFIAVPKF
                     NLYQSLHTAFATSDGHVAEVIVRTRQMHRVAEAGVVALGNPYATAAATAATAAAASGGT
                     AGSAEACADPYEERVDPTRPGWLSRLLDWQQSAPDPDTFWSVLRAELAQDREITVFRAD
                     GGAPATISLPGGASCIDAAYAQYGEAAHGCIGARVNGRLTSLTSRLSDGDTVQLLLAHD
                     ASSGPSADWLEHAHTPAARIAISSWLKAHPDGAAATTTAARAPLSVVGARGGGGNAVAD
                     LPDATVRLAGCCTPVPPDAVAGFVVRGGAVTVHRVQCAAVAQMRSLGRTSVAVHWRATA
                     DCRVTLLAESFGRPHLLADLTEAIAREGVEVVSATVEPPVEQRVRHSYTLQLPDATGLP
                     ALMRAMRDVPGVYDVSRA"
     gene            6974..8419
                     /locus_tag="IE248_RS05765"
                     /old_locus_tag="GCM10010336_11680"
     CDS             6974..8419
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460632.1"
                     /locus_tag="IE248_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11680"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_008742940.1"
                     /transl_table=11
                     /translation="MQLTSPRLRAALLAAASLTLVAAVLPPPKALGIGDPLFPELGNPG
                     YDVLAYDLSFTYKDNRSPLDAVTVIDARAQEPLERINLDFTNGTVAEAEVNGEPARFES
                     VAEDLVLTPARPVAAHMPLHIVIRHTSDPRGRSDGGWVVTDDGLAMANQADAAHRVFPC
                     NDHPSDKAYFTFRITAPAGLTAVANGVPGALPARRAAAPTTWTYRTVHPMATELAQVSV
                     GDSAVVRGTGPHGLPLRDVVPAADRQKLERWLKKTPGHIEWMEQRVGRYPFENYGVLIA
                     RAKTGFELETQTLSLFEHGLFTEEGYPEWYVESVMVHELAHQWFGDSVTPRAWSDLWLN
                     EGHATWYEALYADGLGKYSLERRMREAYQRSDQWRAAGGPPAAPKPAAPGQKIGLFRPA
                     VYDGAALILYALRQEIGAEAFDRVERSWVGEHRDAVAGTEDFVRLASREAGRDLGEFLK
                     PWLYGSTTPPMPGHPEWSGAKGA"
     misc_feature    complement(8503..8518)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     misc_feature    complement(8593..8605)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.88"
                     /tool="antismash"
     gene            8704..10218
                     /gene="hflX"
                     /locus_tag="IE248_RS05770"
                     /old_locus_tag="GCM10010336_11690"
     CDS             8704..10218
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="hflX"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237798.1"
                     /locus_tag="IE248_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11690"
                     /product="GTPase HflX"
                     /protein_id="WP_073777242.1"
                     /transl_table=11
                     /translation="MTSSSSPSQDARDARDARDASDPQSFTESLRADALMEEDVAWSHA
                     IDGDRDGDQFERSERAALRRVVGLSTELEDVTEVEYRQLRLERVVLVGVWTSGTVNDAE
                     NSLAELAALAETAGALVLDGVIQRRDKPDPATFIGSGKARELRDIVLESGADTVVCDGE
                     LSPGQLIALEDVVKVKVVDRTALILDIFAQHAKSREGKAQVALAQMQYMLPRLRGWGAS
                     LSRQMGGGGGGGMATRGPGETKIETDRRRIREKMAKMRREIAEMKTGREIKRQERRRNK
                     VPSVAIAGYTNAGKSSLLNRLTGAGVLVENALFATLDPTVRRAETPSGRIYTLADTVGF
                     VRHLPHHLVEAFRSTMEEVGDSDLILHIVDGSHPAPEEQLAAVREVIREVGAVNVPEIV
                     VINKADAADPLVLQRLLRIERHSIAVSARTGMGIAKLLELIDTELPRPEVEVEALVPYT
                     RGSLIARAHAEGEVISEEHTPEGTLLKARVHQELAADLAPYVPAKH"
     gene            complement(10318..11496)
                     /locus_tag="IE248_RS05775"
                     /old_locus_tag="GCM10010336_11700"
     CDS             complement(10318..11496)
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237800.1"
                     /locus_tag="IE248_RS05775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11700"
                     /product="serine protease"
                     /protein_id="WP_047960718.1"
                     /transl_table=11
                     /translation="MRPNRPVTAALCAAALALTAAACGPGDGEAGGDAKPTVAASLPSG
                     ADGIKIPDELKDKLKEHGFDLEKWRGGAWKNWNQDDWLREAGDYVNPIIEDLWDPDRMR
                     GAEEPKGPSVDPDAGKDQGVTDPTPAAVAAKPAPAPYHANVPESGKVFFDGPEGSMVCS
                     ATVVKDPAHPGKSNMVWTAGHCVHSGKSGGWYRNIAFVPSYNNAGKPATALKGAPREQV
                     APFGVWWSDWAQTSDQWIATGGPTGGAGAPYDFAMLHVTPEKGSGKSLEETVGSALPVE
                     FNAPAVPKIASMTATGYPAAAPFDGQKAYQCTDRPGRLSLVAADPVMYRIGCTMTGGSS
                     GGGWIAAGSNGKPALVSNTSIGPTKAGWLAGPKLGPEAKKLFEGVSGKFRGQ"
     misc_feature    complement(11701..11712)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            11770..13128
                     /locus_tag="IE248_RS05780"
                     /old_locus_tag="GCM10010336_11710"
     CDS             11770..13128
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (50-384). E-value: 8.7e-89.
                     Score: 289.8. Matches aSDomain:
                     nrpspksdomains_IE248_RS05780_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018551521.1"
                     /locus_tag="IE248_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11710"
                     /product="diaminobutyrate--2-oxoglutarate transaminase
                     family protein"
                     /protein_id="WP_229895144.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.6e-88, bitscore:
                     291.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALTEQAAAAATVVTQGSRGSAAAAEGILGRQAQRESAARTYARS
                     LPIVPVRARGLTIEGADGRRYLDCLSGAGTLALGHNHPVVLEAIRGVLDSGAPLHVLDL
                     ATPVKDAFTSELFANLPAGLAADARIQFCGPAGTDAVEAALKLVRTATGRSGLLAFTGA
                     YHGMTAGALDASGGAPEVRVTRLPYPQDYRCPFGVGGAEGARLAARWTESLLDDPKSGV
                     PSPAAMIVEPVQGEGGVIPSPDAWLRRMREITAARGIPLIADEVQTGVGRTGAFWGVDH
                     AGVVPDVMVLSKAIGGSLPLAVIVYRAELDVWAPGAHAGTFRGNQLAMAAGTATLAYVR
                     ENGLAERAATLGDRMLAALRGLIPAHPCVGDVRGRGLMIGVELIDPDTGAAAPGLASAV
                     RRECLDRGLIVELGGRHSSVVRLLPPLTVTDEQATAVLDRLADAIPAAGRRPH"
     aSDomain        11920..12921
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS05780_Aminotran_3.1"
                     /evalue="8.70E-89"
                     /label="IE248_RS05780_Aminotran_3.1"
                     /locus_tag="IE248_RS05780"
                     /protein_end="384"
                     /protein_start="50"
                     /score="289.8"
                     /tool="antismash"
                     /translation="VRARGLTIEGADGRRYLDCLSGAGTLALGHNHPVVLEAIRGVLDS
                     GAPLHVLDLATPVKDAFTSELFANLPAGLAADARIQFCGPAGTDAVEAALKLVRTATGR
                     SGLLAFTGAYHGMTAGALDASGGAPEVRVTRLPYPQDYRCPFGVGGAEGARLAARWTES
                     LLDDPKSGVPSPAAMIVEPVQGEGGVIPSPDAWLRRMREITAARGIPLIADEVQTGVGR
                     TGAFWGVDHAGVVPDVMVLSKAIGGSLPLAVIVYRAELDVWAPGAHAGTFRGNQLAMAA
                     GTATLAYVRENGLAERAATLGDRMLAALRGLIPAHPCVGDVRGRGLMIGVELI"
     misc_feature    complement(13653..13672)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.61"
                     /tool="antismash"
     gene            14001..16055
                     /locus_tag="IE248_RS05785"
                     /old_locus_tag="GCM10010336_11720"
     CDS             14001..16055
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962100.1"
                     /locus_tag="IE248_RS05785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11720"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_190030101.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.9e-73, bitscore:
                     242.9, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGRSEASSLSPARDAEDWTVGVPAPQFGPAGFPASGLPGGWPGA
                     AEAGASAYGGSEAADLPGSGTPGPAPAPRSDPAASVPRQKDGTGRARVGGAGPLGPEPA
                     ALPDLLDHPDPAVAAEAAAVENLLRCWVRETGIGRPDGPVGTLLRIPLPASGAALLVAV
                     RYWSPSGWHRFSPPRFEAAPAHAPALDAVTLAALIAREGNPASRGGADLVGRVSDSVHR
                     TAEFIADRREHPSPPAPVAGDLFLTSEQSLLLGHPLHPTPKSREGLSEAEVRPYSPELH
                     GSFPLHWLAVAPAALATDSAWTERGRPVPAAQLLGRLAPGLTLPDGATPLPLHPWQARD
                     LLRRPAVTALRDAGLLTDLGPHGEPWHPTSSIRTVHRPGAPAMLKLSLGLRITNSRREN
                     LRKELHRGVEVHRLLRTGLAEQWQAAHPGFDIVRDPAWVAVNAPDGTPVQGLDVLLRHN
                     PFRSGDDALCVAALTAPRPWPGRTTMRSRLAEIVSRLAGATGRSTSAVSAEWFLRYLDH
                     VVLPVLAFDALAGVALEAHQQNTLVILDPAGWPLGGRYRDNQGYYFRASRRTELERRLP
                     GIGAASDTFVSDAITDERFAYYLGVNNVLGLIGAFGSARLADERVLLAAFRRFLGKAAG
                     LGPLPAQLLDSPTLRCKANLLTRLGGLDELVGPVDTQSVYVTIANPLHD"
     gene            16087..16725
                     /locus_tag="IE248_RS05790"
                     /old_locus_tag="GCM10010336_11730"
     CDS             16087..16725
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742945.1"
                     /locus_tag="IE248_RS05790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11730"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_100583319.1"
                     /transl_table=11
                     /translation="MPSTDETVELRLNAQLLPLLAEADLLDSPAAWGSATTAAGAFRLE
                     PVRLERDLELLTRWMNDPEVAAYWELGGPAAVTAAHLRAQLDGDGRSIPCLGLLDGTPM
                     SYWEIYRADLDPLSRHYPARPHDTGIHLLVGDGTNRGRGLGTALLRAVADLVFDNRPRC
                     TRVIAEPDIRNTPSVTAFLNSGFRCPAEIDLPEKRAALMIRERALRNLL"
     misc_feature    complement(16799..16813)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.09"
                     /tool="antismash"
     misc_feature    16807..16824
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.33"
                     /tool="antismash"
     misc_feature    16810..16823
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.68"
                     /tool="antismash"
     misc_feature    complement(16811..16824)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.95"
                     /tool="antismash"
     gene            16857..18734
                     /locus_tag="IE248_RS05795"
                     /old_locus_tag="GCM10010336_11740"
     CDS             16857..18734
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742946.1"
                     /locus_tag="IE248_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11740"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_190030102.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.3e-71, bitscore:
                     236.9, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNFPAAHDFTETTVAPSPQHPCTPPEINPVTWAFAGRALLAKML
                     GEFAYEGIISPVPAPAPAAGDAWTLTLDDGSSLGFRARRRSYGSWQVTPDTLTLTPAPP
                     SYGSPTPAGHPTAFGDPYAFLIRARSLLGLDGATLGHLVRELSATLTADARIAHTALTA
                     DVLADLDYAELEGHQTGHPWLVLNKGRIGLSAADTAAWAPEARTRQRLPWLAAHTSLAE
                     YRGTAGLEDPARLYRAELDPVTRAAFDQALRDRGLDPSGYLYLPVHPWQWDEVVLPLFA
                     QALASGALVPLPADPDVRLPQQSIRTFLNLTRPDRHSVKLPLSVFNTMVWRGLPSDLAL
                     AAPAVTSWIHSLRDADPFLRDECRVVLLGEVASVTVRHPVYEQLPEVPYQYKELLGAIW
                     REPLTGHLAPGERARTLASLLHTDPRGRSFTAELVARSGLAPTVWLQRLFAALLPPLLR
                     FLYRYGTVFSPHGENAIVIFDEQDVPVRLAVKDFVDDVNISREPLPEHASMPAEVRAAL
                     LTEPPAFLTQFIHSGLFIGVFRYLCALCEDRLGVPEIEFWSLVRAEILRHQARFPELKE
                     RYELFDLLTERIDRLCLNRNRLHEDGYRDRPDRPHAVTHGTVPNPLYQP"
     misc_feature    complement(16858..16874)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.69"
                     /tool="antismash"
     gene            18787..20757
                     /locus_tag="IE248_RS05800"
                     /old_locus_tag="GCM10010336_11750"
     CDS             18787..20757
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520798.1"
                     /locus_tag="IE248_RS05800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11750"
                     /product="ATP-dependent DNA helicase"
                     /protein_id="WP_190030103.1"
                     /transl_table=11
                     /translation="MTKPSLPDLLHAAVSAVGGTERPGQVAMAEAVGEAIDDNSHRLIQ
                     AGTGTGKSLGYLVPALAHGERVVVATATLALQRQLVERDLPRTVEALHPQLRRRPQFAM
                     LKGRSNYLCLHRLHEGAPQDEEEGLFDQFEAATPTSKLGKDLLRLRDWADETETGDRDD
                     LTPGVSDKAWAQISVSSRECLGATKCAYGAECFAEAARERAKLADVVVTNHALLAIDAI
                     EGAPVLPQHEVLIVDEAHELVSRVTGVATGELTPGQVNRAVKRAAKLVDEKSADSLQTA
                     SESFERVMELALPGRLEEIPEDLGYALMALRDAARNVISAIGSTRDKSVHDEDAVRKQA
                     LAAVDNIHTVAERITNGSEYDVVWYERHDRFGATLRVAPLSVSGLLREKLFEDRSVVLT
                     SATLKLGGDFNGVAASLGLSPEGVEGDDVPVWKGLDVGSPFDYPKQGILYVAKHLATPG
                     REGTRGDMMDELAELIEAAGGRTLGLFSSMRGAKAAAEELRGRLDNPILLQGEETLGEL
                     IKAFAADPKTCLFGTLSLWQGVDVPGPSCQLVVMDRIPFPRPDDPLMSARQKSVEEHGG
                     NGFMAVAATHAALLMAQGAGRLVRASGDRGVVAVLDPRLATARYGSFLRATLPDFWYTT
                     DRNQARRSLAAIDAGAQAEGK"
     gene            complement(20829..21623)
                     /gene="lexA"
                     /locus_tag="IE248_RS05805"
                     /old_locus_tag="GCM10010336_11760"
     CDS             complement(20829..21623)
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526308.1"
                     /locus_tag="IE248_RS05805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11760"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_008742948.1"
                     /transl_table=11
                     /translation="MTTTADSAATITAQNRSQSRLEPVHAMNDASLNPEAEPVRPARSL
                     PGRPPGIRADSSGLTDRQRRVIEVIRDSVQRRGYPPSMREIGQAVGLSSTSSVAHQLMA
                     LERKGFLRRDPHRPRAYEVRGSDQPSSQPTDTTGKPAASYVPLVGRIAAGGPILAEESV
                     EDVFPLPRQLVGDGELFVLKVVGDSMIEAAICDGDWVTVRRQPVAENGDIVAAMLDGEA
                     TVKRFKREDGHVWLLPHNAAYQPIPGDEATILGKVVAVLRRV"
     misc_feature    complement(21686..21701)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.09"
                     /tool="antismash"
     misc_feature    21687..21700
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.93"
                     /tool="antismash"
     misc_feature    complement(21687..21700)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.77"
                     /tool="antismash"
     misc_feature    complement(21697..21710)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.92"
                     /tool="antismash"
     misc_feature    complement(21703..21712)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.59"
                     /tool="antismash"
     misc_feature    complement(21763..21776)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    complement(21911..21925)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 21.93"
                     /tool="antismash"
     misc_feature    complement(21942..21956)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.23"
                     /tool="antismash"
     misc_feature    complement(21968..21982)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(21978..21988)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            22092..22604
                     /gene="nrdR"
                     /locus_tag="IE248_RS05810"
                     /old_locus_tag="GCM10010336_11770"
     CDS             22092..22604
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488320.1"
                     /locus_tag="IE248_RS05810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11770"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_008742949.1"
                     /transl_table=11
                     /translation="MHCPFCRHPDSRVVDSRTTDDGTSIRRRRQCPDCSRRFTTVETAS
                     LMVIKRSGVTEPFSRTKVISGVRKACQGRPVTEDALAKLGQRVEEAVRATGSAELTTHD
                     VGLAILGPLQELDLVAYLRFASVYKAFDTLEDFETAIAELRVPRSHPDECEQGGAAQVP
                     VPASAAD"
     gene            22734..25619
                     /locus_tag="IE248_RS05815"
                     /old_locus_tag="GCM10010336_11780"
     CDS             22734..25619
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526310.1"
                     /locus_tag="IE248_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11780"
                     /product="vitamin B12-dependent ribonucleotide reductase"
                     /protein_id="WP_073796347.1"
                     /transl_table=11
                     /translation="MTETASGSARGSRAKGTKAAKGGLRIERIHTTPGVHPYDEVSWER
                     RDVVMTNWRDGSVNFEQRGVEFPDFWSVNAVNIVTSKYFRGAVGTPQRETGLKQLIDRI
                     VKTYTKAGEDFDYFASPADVEIFEHELTYALLHQIFSFNSPVWFNVGTPQPQQVSACFI
                     LSVDDSMESILDWYKEEGMIFKGGSGAGLNLSRIRSSKELLSSGGNASGPVSFMRGADA
                     SAGTIKSGGATRRAAKMVVLDVDHPDVEAFIETKVKEEEKIRALRDAGFDMDLGGDDIT
                     SVQYQNANNSVRVNDEFMTAVENGTEFGLRSRMTGEVIEKVDAKALFRKLAEAAWACAD
                     PGIQYDGVINNWHTCPESGRITASNPCSEYMHLDNTSCNLASLNLMKFLNDDGKGNQSF
                     DAERFAKVVELVITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYD
                     SDGGRTLAASITSLMTGTAYKRSAELAAIVGPYDGYARNADAHKRVMKQHADANATAPR
                     TQDLDNTIWAAATEAWQDVLRLGEKNGFRNSQASVLAPTGTIGLAMSCDTTGVEPDLAL
                     VKFKKLVGGGSMQIVNGTVPQALRRLGYQEEQIEAIVTHIAEHGVVVDAPGLKTEHYEV
                     FDCAMGERSISAMGHVRMMAAIQPWISGAISKTVNMPETATVEEIEEIYFEAWKMGVKA
                     LAIYRDNCKVGQPLSAKKKEEEKEEVTAKTEETIRAAVEKVIEYRPVRKRLPKGRPGIT
                     TSFTVGGAEGYMTANSYPDDGLGEVFLKMSKQGSTLAGMMDAFSIAVSVGLQYGVPLET
                     YVSKFTNMRFEPAGMTDDPDVRMAQSIVDYIFRRLALDFLPFETRSALGIHTADERQRH
                     LDTGSYEPLDEEIDTESLSQSAPLTAVPAPKPMAVIEVPAPKTAHSSAELVEMQLGVSA
                     DAPLCFSCGTKMQRAGSCYICEGCGSTSGCS"
     gene            25771..26469
                     /locus_tag="IE248_RS05820"
                     /old_locus_tag="GCM10010336_11790"
     CDS             25771..26469
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072901.1"
                     /locus_tag="IE248_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11790"
                     /product="DUF6215 domain-containing protein"
                     /protein_id="WP_229895145.1"
                     /transl_table=11
                     /translation="MADGFAGSKKEMNVGAQAVAAVVAVGGVLGGAWGLGEFFELGHSP
                     EDVKPAVCSTTKDELPAEYASGAKLCAALNRPDLPALLGTPAEQPLNATGNGRWITFGS
                     GVKIAASEAKVQLKTHTVQVSASYDDLPVDQAVEVLGVTAQQQTVLGHPAVVYSYPTIA
                     ITFDFGNGKTGSGPGGIARHVMVAADAKGGGGTSFDVVVWREDGTLPDDMALLRVAEQV
                     LPTVPGWSAG"
     misc_feature    25800..25811
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            26618..27457
                     /locus_tag="IE248_RS05825"
                     /old_locus_tag="GCM10010336_11800"
     CDS             26618..27457
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266990.1"
                     /locus_tag="IE248_RS05825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11800"
                     /product="arylamine N-acetyltransferase"
                     /protein_id="WP_190030104.1"
                     /transl_table=11
                     /translation="MWSGDELDLDAYLARIGYDGPVGDDGELKADLATLYAVHRAHTAA
                     ITFESLDVLLGRPVALDIEALQDKIVQGRRGGYCYEQNSLLAAALERIGFEVSGRGARN
                     RTRGDTLLAVTHAVLVVTVDGEPWLCDAGFGYLGPREPVPLARPGAEIRQGAWTYTVRE
                     EDGGVLALCLRREGTWRELYAFSPQHYHPVDYVVLNHYSSSHPRSAFIGQVIVQLPGDA
                     VRLALVGRELTRLYPDGRTERQPVEPGELVPLLAREFGLRLSERDAAELVLINRAED"
     gene            27490..28095
                     /locus_tag="IE248_RS05830"
                     /old_locus_tag="GCM10010336_11810"
     CDS             27490..28095
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1258: Antibiotic biosynthesis monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385166.1"
                     /locus_tag="IE248_RS05830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11810"
                     /product="YdbC family protein"
                     /protein_id="WP_073777226.1"
                     /transl_table=11
                     /translation="MLVKWIRCTVTDRRGFERGQRKWAGLPGEPGFRGQGGGWSRGRQG
                     VAHVFTFWESRSFYDSFMARSHDRLAASQNGTYTAMRVTLFDHRFDVKTGFEPRFTDAD
                     VVRVAHTRVREGRVDHFAHMQEKVWNPAMAGSPGMIRGLFGEAPGREFLVLSMWRAAAE
                     HGKYRPERVERLSLRAQTEADVEALTGDVVDLEPSWTV"
     gene            28176..28835
                     /locus_tag="IE248_RS05835"
                     /old_locus_tag="GCM10010336_11820"
     CDS             28176..28835
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965783.1"
                     /locus_tag="IE248_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11820"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_037798251.1"
                     /transl_table=11
                     /translation="MARPRRIVLVRHGESEGNLDDTVYEREPDHALRLTPAGRAQAAET
                     GVRLRELFGDETISAYLSPYRRTLQTFRELRLDPVRVRAREEPRLREQDWGNWQDRDDV
                     RLQKAYRDAYGHFFYRFAQGESGADVYDRVGSFLESLYRSFEAPDHPENVLLVTHGLTM
                     RLFCMRWFHWSVAEFEALSNPGNGEYRVLLRGPDGRYRMDRPFERWTTPEPYDLDG"
     gene            28847..29764
                     /locus_tag="IE248_RS05840"
                     /old_locus_tag="GCM10010336_11830"
     CDS             28847..29764
                     /EC_number="3.2.2.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973213.1"
                     /locus_tag="IE248_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11830"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_037798254.1"
                     /transl_table=11
                     /translation="MTSDSSSERRYARAMASLRGLALGDALGSQYFVPVNYPLLKRREV
                     PAGNDTWQWTDDTEMACSVVAVLAEHGRVDQDALALSFAHHHDFDRGYGPAVNRMLRLV
                     REGADWRTLAAELFNGQGSWGNGAAMRIAPLGAWYADDPEQATHQAEISAYTTHQHREA
                     VCGAMAVAAAAALAANPEGPPAAADLLDGVIALVPRSAVGAGLRRARDMLDYGDATTVA
                     AVLGCGRRTSAHDTVPFALWSAARSLDDYERAFWTTAQVGGDVDTTCAIVGGVLGARGE
                     AVLPEAWLARTETLPAWLPESARR"
     gene            29940..31856
                     /locus_tag="IE248_RS05845"
                     /old_locus_tag="GCM10010336_11840"
     CDS             29940..31856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951291.1"
                     /locus_tag="IE248_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_11840"
                     /product="DUF4173 domain-containing protein"
                     /protein_id="WP_190030105.1"
                     /transl_table=11
                     /translation="MSENADEVDSGAAEGAVAGGAAVQGSAARGAGAQGPAAQGFAAQG
                     SGAQGAAAEPAKPGSAAPAGSGAGVAAGAGGGATATPVTAAAAGGAHAGAAASAGPAGA
                     GAGSGGPVGGGPAGGFDASAWQARQALIQQQRARAAAPAAWAVRIRPVEAAPIRTATLI
                     AAVLAGLAAALLLGDGMGPGLLVAVLPAIAAAYFAARAAGRKARPWTVVWAVGCVALLV
                     VPALRDSAWPATLAILSAVSLASLALHGVRTWPGVLFSPFGFVDSAVNGVGWAWTGLRS
                     RSGGLSRDRWLPVAKAAAVALGLLVVFGTLFASADAAFADLLGDLTPEVSVGDGPVRIL
                     LFVLGAVLALAAARTTAAPLRWDRLRIAPGRARSRLEWALPLVVLNLLFAGFNAVQLAV
                     LFGGYDKVLKSTGHRSYAEYAQQGFWQLLWATLLTLVVIALALRWAPRGGAGDRRFVRA
                     VLGTLCALTLVVVASALRRMDFYVDAYGLTRLRVSVAAMELWLGLVLVLIMAAGVFGAR
                     WLPRAVAGSAAAAVLAFGLLSPDGMVAERNVTRFQQDAKIDLAYFQSLSADAAPALDRL
                     PEPQRSCALRGINDELAEAGDVPWYAMSLGEYRARKILRERPLKASYEDCSRLGTFGSR
                     VEP"
ORIGIN
        1 ccgggcgacg tggtcaccgt cgacatcacc tacgcggccc cgcaccacct gctggccgag
       61 ggcccgacgc ggtccgtacg ccgtacccgc gcgggcgacg cgtgggagaa gcgcaacgcc
      121 gctccgccgc agccggcggg cgtcatgctc ggcatcccca ccctcggcgt cccggccccc
      181 ctgcccccga ccacctcggg ctgcgccgtc tcctcctgac gcctgcccgg ccctgccccg
      241 ccccacccgg cgttccaggc gtgggtccgg gcagagcccc aggccccacc agcccgcccg
      301 gtgccgtggg accgggctcc gggcagcgcc cgggaaacgg cggcggcgga agggcggcgg
      361 ggccgcgcgg cggcacggtg tcgaggccgg gcgggaggcc ctccgccacc ccgctccggc
      421 cggcgacggc taggctgcgg atcatgctcg tagccgccgc cgtctgcccc gccccgccgc
      481 tgctcgtacc ggaggtcgcc gccggggccg ccgccgagct cgcggacgcc cgtaccgcct
      541 gctccgacgc gctcgccgtc ctcgccgccg cccgccccga ccgcctggtc gtggtcggcg
      601 ccgccggggc ggaccacacc ggcccctacc cccagggctc ccgcggcagc ttccgcggct
      661 tcggggtggc cgccgacgta cggctcggcg aaggcgagga gggcccgcgt gtgctgccca
      721 cctcgctcgc cgtcgccgcc tggctgctcg cccgcgcgcg ctggggcgcg gcccccgtcg
      781 agggcctcgg tgtcgccgag cccctggagg ccgacgcctg cctgcgcacc ggccgggaac
      841 tcgcagtcac cgacgaccgc gtcgccctcc tcgtcatggg cgacggcagc gcctgccgca
      901 ccgtgaaggc ccccgggtac ctcgacgagc gcgccaccgc cttcgacgcc gaggcggccc
      961 gcgccctcgg cgcggccgac accgccgccc tcgcggccct cgaccccggg ctcgcccggg
     1021 agctcaaggc cgccggacgg gccccctggc aggtgctcgc gggcgccgcc gagggcgcgg
     1081 gcctcgacgg ccggctgctg tacgacgagg ccccgtacgg ggtcggctac ttcgtcgcca
     1141 cctggtcctg aaacctcgcc cgggccgtcg ctgaacgccg ccgctggacg cccctgaggg
     1201 ccgtcagagc gcctccgggc acacggaagg ggcgcgaggg caccctgccc ccgcgcccct
     1261 tccgggaccg cgtcaggaag ccgccggcgg cgtctgcccg ccggggccgt ccttgtgcgc
     1321 gatcttgccc agggcgtcct tcgccttgct cgtgccggtc tcgatccggc cgtggtactt
     1381 gcccttggtc ttggagtcca cgacctgggc caccttgtcc agattctggc cgatcctgcc
     1441 ctcgtgctgc tgcgcgaggt ctccgacctt gtccttcgcc ggcgcgagct tggccttcag
     1501 attgtccagc agacccatgg gtcaccttcc agtggcggtg gctacgtgcg ggcgccctcg
     1561 ccggtctcgc tgtccgctgc ggcctccgcc gactgctgct tcggaatctc cacggcttcc
     1621 gccgcaggag ccccctcctc agccgtcccg gcctctgccc cctcggacgc ggccgtcaga
     1681 tccccggccg cgacctcctc ggtcgaagcc tggttcttac ggccaaaaaa ccggccaaaa
     1741 acgcccatgt ctgctcctat aacgctgctc gtgtgagtga agttccgccc ggttcgaacc
     1801 ggcttgcgcc cgtgctcgcg ccgggcccgc gccggacgct cgcccggacg gaaccacgcc
     1861 agggcaacga ccccgcccgg gccccgtcac gtaactcgat cgggtacacg ccggtatctg
     1921 gccagggctt cgcgaggggt ttgcgagact ggggcggtga ggaaagcagc ccccgcaccg
     1981 cgggtcatcg ccgtcgtcgg tcccaccgcg gccggaaagt ccgacctggg cgtcgccctg
     2041 gcccgccatt tcgacggcga ggtcgtcaac gccgactcca tgcagctgta ccgggggatg
     2101 gacatcggca ccgccaagct gacggtcgag gagcgcggcg gagtcccgca ccacctcctc
     2161 gacgtctggg aggtgaccga gaccgccaac gtcgccgagt accagcggct ggcccgcgtc
     2221 gagatcgaca agctcctcgc cgagggccgc acgccggtgc tcgtcggcgg atccgggctg
     2281 tacgtccgcg gcgccctcga cgccatggag ttccccggca ccgatccaga ggtccgggcc
     2341 cggctggagg aagaggtcac cctgcgcggc cccggcgccc tgcacgcgcg gctcgccgcc
     2401 gccgatcccg ccgccgcggc ggccatcctg cccagcaacg gccgccggat cgtccgcgcc
     2461 ctggaggtca tcgagatcac agggcggccg ttcaccgcga acctgcccgg tcacgagtcg
     2521 gtctacgaca ccgtccagat cggcgtggac gtcggccggc ccgaactcga cgagcggatc
     2581 gcgcggcgcg tcgaccggat gtgggaggac gggctggtcg acgaggtccg cgccctggag
     2641 gcccgggggc tgcgtgacgg aatcaccgcc tcccgcgccc tcggctacca gcaggtgctg
     2701 tccgctctcg cgggtgaatg caccgaggag gaagccaagg ccgagaccgt ccgcgccacc
     2761 aagcggttcg cccggcgtca ggactcctgg ttccgccgcg acccgcgcgt gcactggctc
     2821 agcggagccg tcgtggaccg cggggaactc cccgggctcg cgcagtcgtt ggtcgaacga
     2881 gcggttacag cctgatcacg tgatggcatc gggacgcccc gtgcgccagt cggcgccccg
     2941 ggagcgtgcc atcatcaaac ttctgaacag cggcgtacga agtccgagtg gggagggcgc
     3001 gtggctatgg aggccggccc tcgaaacact gggcaggacg agacccggcg ggaaaccgac
     3061 ccggtgcgac tcgacgggtc cgagggcccc gtcgagcccg acggagccgt cggggccctg
     3121 gccgggcccg acaccctcgg gctgcccgcc gagcccgcgc ggctgagccc cgacgggccg
     3181 gacgcgccgg accccgccga ggtggaggcc gcgtccggcc ccgagttcga ggtggagctg
     3241 cgcccgcagc gccgcctgcg catctggcag atcgccccca tcgtgctgct ggccctggcc
     3301 ggctcgctga tgttcgcgtt cccgctcgcc ttcgaattcg gcgacggcgg cgcggtggtc
     3361 gccatgctgg gcttcctcat cagctcctgc gcgggcggct ggggcatgat ggccgcccgc
     3421 cgggtgggct acagctggcc cgggctgccg cccaggggat cggggcgccg ccccgactgg
     3481 cgcatggccg cgctgtacgc gctggccgcg ctggccgtcg tagcgctcgc ggtgtaccgc
     3541 gtggcgcggc tgcgctagcc gccggctgcc acccgtaccc cgtccggccc tcggaccacg
     3601 cagggcccgt cggccgcgtc tcggtacgat gggcgcgtga cgcagaccag cctctccttc
     3661 ctcaagggcc acggcaccga gaacgacttc gtgatcgtcc cggacccgga caacgccatc
     3721 gagctgcccg cgaccgccgt cgcgaagctg tgcgaccggc gggccggcat cggcggcgac
     3781 ggcgtgctgc acgtcgtgcg ctccgccgcg caccccgagg cgaaggccat ggccggcgag
     3841 gccgaatggt tcatggacta ccgcaacagc gacggttcca tcgccgagat gtgcggcaac
     3901 ggcgtccgcg tcttcgcccg ctacctccag tacgccgggc acgtcgagcc cggtgacctc
     3961 gccatcgcca cccggggcgg cgtcaagcgc gtccacctcg acaagcgcgg cgacgtgacg
     4021 gtctccatgg gccgcgccga gttccccgag ggcgaggtga ccgtctccgt cggcgaccgg
     4081 tcctggcccg cgcggaacgt caacatgggg aacccgcacg cggtggcgtt cgttgacagc
     4141 ctggacgatg ccggaaccct gtacgacgcg cccccgttca gcccggcctc cgcctacccg
     4201 gcaggtgtca acgtcgagtt cgtcgccgac cgaggcccgc ggcacgtcgc catgcgcgtc
     4261 cacgagcgcg gctccggcga gacccgctcc tgcggcaccg gcgcctgcgc cgtcgccgtg
     4321 gccgccatcc ggcgcgacgg cgtggacccc gccgagaccg gcgaacaggt cacctacacc
     4381 gtcgatctgc ccggcggaac cctggtcatc acggagtacc ccgacggccg gatcgacatg
     4441 accggacccg ccgtcatcgt cggctcgggc gagttcgacg cgacctggct cgccgaaacg
     4501 gccttcgtct gaagcttccc tctaatgggt gatccgtttc acgctgagcg agaggtggac
     4561 tgcgccacgt ggtggggtcg gtagcatcag gcaccggccc tgagggcgca ccccatgccc
     4621 gccaccgccg gtcgaagccg ccggaggtgc ccatgagtgc agaggccacg aaccccgaag
     4681 cacgttccga agcacgcccc gagctccgca gacgtggccg caccaggctt gatctgcgac
     4741 gactcgggcg agcggccctg ctcgggccga catcccgcga ccggctgccc gatgccatcg
     4801 ggcacgtcgc ggaggcgcac cgcgcccacc atccggacgc cgacctgtcc atcctgaggc
     4861 gcgcgtacgt gctcgcggag tcctcccacc gcggccagat gcgaaaaagt ggtgagccgt
     4921 acatcacaca tccgctcgcc gtgaccctga tcctggccga actcggcgcc gagacaacga
     4981 ccctgacggc ctctctgctc cacgacacgg tcgaggacac cgaggtgacc ctcgatcagg
     5041 tccgcgagga gttcggcgac gaggtctgct tcatcgtcga cggcgtcacc aaggtcgaga
     5101 agatcgacta cggcgccgcc gccgagcccg agaccttccg caagatgctc gtcgccaccg
     5161 gcaacgacgt ccgcgtcatg tccatcaagc tcgccgaccg cctccacaac atgcgcaccc
     5221 tcggcgtcat gcgccccgac aaacaggcgc gcatcgccaa ggtcacccgt gacgtcctca
     5281 tcccgctcgc cgaacgcctc ggcgtccagg cgctcaagac cgagctggaa gacctcgtct
     5341 tcgcgatcct gcaccccgag gagtacgagc acacccgcgc gctgatcgcc gcccacgccg
     5401 gcgagcgcga cccgctgccc gccatcgcgg agtccgtccg ggtcgtcctg cgcgaggccg
     5461 gcatccacgc cgaagtcctc gtacgccccc ggcacttcgt ctccgtccac cggatctccc
     5521 gcaagcgcgg ggagctgcgc ggctccgact tcggtcggct gctgatcctg gtcggggaga
     5581 acgccgactg ctacggcgta ctgggggagc tgcacacctg cttcaccccg gtggtctcgg
     5641 agttcaagga cttcatcgcc gtcccgaagt tcaacctcta ccagtcgctg cacaccgcct
     5701 tcgccacctc cgacgggcac gtggccgagg tcatcgtccg gacccggcag atgcaccggg
     5761 tcgcggaggc cggggtcgtc gcgctcggca atccgtacgc cacggcggcg gccaccgcag
     5821 caaccgcggc cgccgcctcg ggcggcacgg ccgggtccgc cgaggcctgc gcggacccgt
     5881 acgaggagcg ggtggacccc acgcggcccg gctggctctc gcgcctgctc gactggcagc
     5941 agtccgcgcc cgaccccgac accttctgga gcgtgctgcg cgccgagctg gcccaggacc
     6001 gggagatcac cgtgttccgg gcggacggcg gggcccccgc cacgatcagc ctgccgggcg
     6061 gggccagctg tatcgacgcc gcctacgcgc agtacggcga ggcggcccac ggctgtatcg
     6121 gcgcccgggt caacgggcgc ctcacctccc tgacctcccg gctctccgac ggggacaccg
     6181 tccagctgct gctcgcccac gacgcgtcct ccgggccgtc cgccgactgg ctggagcacg
     6241 cgcacacccc ggccgcccgg atcgccatca gcagctggct caaggcccac ccggacggcg
     6301 ccgccgccac caccacggcc gcgcgggcgc cgctgtcggt cgtcggggcc cgaggcggcg
     6361 gcggcaacgc ggtcgccgac ctgccggacg cgaccgtacg gctggcgggc tgctgcaccc
     6421 cggtgccgcc ggacgcggtc gcgggattcg tcgtacgggg cggggccgtc accgtgcacc
     6481 gggtccagtg cgcggccgtc gcgcagatgc gctccctggg ccgcacctcc gtcgccgtgc
     6541 actggcgggc caccgccgac tgccgcgtca cactgctcgc cgaatcgttc ggccgcccgc
     6601 acctgctggc cgacctgacc gaggcgatcg cccgcgaggg cgtcgaggtc gtctccgcga
     6661 ccgtcgaacc gccggtcgag cagcgggtcc ggcactccta cacgctccag ctgcccgacg
     6721 cgaccggcct gccggcgctg atgcgggcca tgcgggacgt cccgggggtc tacgacgtga
     6781 gccgcgcctg agggtgccgt gacgggggtg acagggggtg gcggggggcc gccgcgcggt
     6841 ggggagccgt ggcgccgggc aaggcccctc cacgcgcgct gtcgggcccg cggccctgcc
     6901 ggaggatccc gttcgggtgg actcgtcgcg cgtcgtgtgc ggccgcgcca cgggcgctgg
     6961 taacccgtgg tggatgcagc tcacctcccc acgcctgcgc gccgccctgc tcgccgcggc
     7021 ctccctcacc ctcgtcgccg cggtgctgcc cccgccgaag gcgctcggca tcggcgaccc
     7081 gctcttcccg gagctcggga accccgggta cgacgtgctc gcgtacgacc tctccttcac
     7141 gtacaaggac aaccggagcc cgctcgacgc cgtcaccgtc atcgacgccc gcgcccagga
     7201 gccgctggag cggatcaacc tggacttcac gaacgggacg gtcgcggagg ccgaggtcaa
     7261 cggggagccc gcgcggttcg agagcgtggc ggaggacctc gtactgacgc cggcccggcc
     7321 ggtggcggcg cacatgccgc tccacatcgt gatccggcac acgagcgatc cgcggggccg
     7381 cagcgacggc ggctgggtgg tcaccgacga cggcctggcc atggccaacc aggcggacgc
     7441 cgcgcaccgg gtgttcccct gcaacgacca cccctccgac aaggcgtact tcaccttccg
     7501 gatcactgcc cccgccgggc tcacggccgt cgccaacggg gtgccgggcg ccctccccgc
     7561 ccgccgcgcg gcggccccca cgacctggac gtaccggacc gtgcacccga tggccaccga
     7621 gctggcacag gtctccgtcg gcgactcggc cgtggtgcgg ggcaccggac cgcacgggct
     7681 gccgctgcgt gacgtggtgc cggccgccga ccgacagaag ctggagcgct ggctgaagaa
     7741 gaccccgggg cacatcgagt ggatggagca gcgggtcggc cggtacccct tcgagaacta
     7801 cggggtgctg atcgcccggg ccaagacggg cttcgagctg gagacgcaga ccctctccct
     7861 cttcgaacac ggactgttca cggaggaggg ctatccggag tggtacgtgg agtccgtcat
     7921 ggtccacgag ctcgcccacc agtggttcgg tgacagcgtc acgccccgtg cctggtccga
     7981 cctgtggctg aacgaggggc acgccacctg gtacgaggcc ctgtacgcgg acgggctggg
     8041 caagtactcc ctggagcggc gcatgcgcga ggcgtaccag cgctccgacc agtggcgcgc
     8101 ggcgggcggg cccccggccg cgcccaagcc cgccgccccc gggcagaaga tcggactgtt
     8161 ccggccggcg gtctacgacg gggcggcgct gatcctgtac gcgctgcggc aggagatcgg
     8221 cgccgaggcg ttcgaccggg tggagcggag ctgggtgggc gagcaccggg acgcggtcgc
     8281 gggtacggag gacttcgtac ggctggcctc gcgggaggcg ggacgcgacc tcggggagtt
     8341 cctgaagccc tggctgtacg ggagcaccac cccgccgatg cccgggcacc cggagtggag
     8401 cggggcgaag ggcgcgtaag ccgcggcgcg taacgcgcgg cgcgcgcggc ggcgggtggg
     8461 ggccggcggg ggccggcggg attggcggcg ccggaaaagg gtgtgacccc cgggtaacgg
     8521 gcatgtcacc atcgacaggg ccgcgccgcg gggctcccgg ggggaatctc ccggcgatgt
     8581 cacacgttgg acgtgacagt gttaggtcac gcgcggcagt agctttggcc ttggctcggg
     8641 tgccgcccgg gctccgcccg gcccggccgg cgcggacgca accgaaatcg acgtaaggat
     8701 ccaatgacct cctcttcatc cccttcccag gacgcgcggg acgcacgcga cgcacgcgac
     8761 gcgtcggacc cgcagagctt caccgagagc cttcgggccg acgccctgat ggaagaggac
     8821 gtcgcctgga gccacgcgat cgacggagac cgggacggcg accagttcga gcgctccgag
     8881 cgcgcggccc tgcgccgcgt cgtcggcctc tcgaccgaac tcgaagacgt caccgaagtc
     8941 gagtaccgcc agctgcgact ggaacgagtg gtgctcgtcg gcgtctggac ctccggcacc
     9001 gtgaacgacg cggagaactc cctcgcggag ctcgccgccc tcgccgaaac cgccggcgcc
     9061 ctcgtcctcg acggtgtgat ccagcgccgc gacaagcccg acccggctac cttcatcggc
     9121 tccggcaagg cccgcgagct gcgtgacatc gtgctggaga gcggcgcgga caccgtcgtc
     9181 tgcgacggtg agctcagccc cggccagctc atcgccctcg aagacgtcgt caaggtcaag
     9241 gtcgtcgacc gcaccgccct gatcctcgac atcttcgccc agcacgccaa gtcccgagag
     9301 ggcaaggcgc aggtcgcgct cgcgcagatg cagtacatgc tgccgcgcct gcgcggctgg
     9361 ggtgcctcgc tgtcccggca gatgggtggc ggcggcggtg gcggcatggc cacccgaggc
     9421 cccggtgaga ccaagatcga gacggaccgg cgccggatcc gcgagaagat ggcgaagatg
     9481 cgccgggaga tcgcggagat gaagaccggc cgcgagatca agcggcagga acgacgccgc
     9541 aacaaggtgc cctcggtcgc catcgccggc tacaccaacg ccggcaagtc ctcgctgctc
     9601 aaccgcctca cgggcgcggg cgtactggtg gagaacgcgc tgttcgccac cctcgacccg
     9661 accgtgcgcc gggccgagac gccgagcggc cggatctaca ccctggccga caccgtcggc
     9721 ttcgtccggc acctgcccca ccacctggtc gaggcgttcc gctccacgat ggaggaggtc
     9781 ggcgactccg acctcatcct ccacatcgtg gacggctcgc acccggcccc ggaggagcag
     9841 ctggcagcgg tccgcgaggt catccgcgag gtcggcgcgg tcaacgtgcc cgagatcgtg
     9901 gtgatcaaca aggcggacgc ggcggacccg ctggtcctgc agcggctgct gcgcatcgag
     9961 cggcactcca tcgccgtctc ggcccgcacc ggcatgggca tcgcgaagct gctcgaactg
    10021 atcgacaccg agctgccgcg acccgaggtc gaggtggagg ccctggtgcc gtacacccgc
    10081 ggctcgctga tcgcccgggc gcacgccgag ggcgaggtca tctccgagga gcacaccccg
    10141 gagggcaccc tgctcaaggc gcgggtccac caggaactcg ccgcggacct ggctccgtac
    10201 gtaccggcga agcactagca cggcgggggc cgttcgcccc gccgctgcac accgcatgac
    10261 cgagggcccc cgcgatcgcg ggggccctcg gtcatgcagc gggactgcgt gtgtcggcta
    10321 ctggccgcgg aacttgccgc tgacgccctc gaagagcttc ttggcctccg gacccagctt
    10381 cgggccggcc agccagcccg ccttggtggg accgatcgag gtgttcgaca ccagcgccgg
    10441 cttgccgttg ctgcccgccg cgatccagcc gccgccggag gagccgccgg tcatcgtgca
    10501 acctatgcgg tacatcacgg ggtcggctgc gaccagcgac agccggcccg gccggtccgt
    10561 gcactggtag gccttctgac cgtcgaacgg ggccgccgcc gggtagcccg tcgccgtcat
    10621 gctcgcgatc ttcggcacgg ccggagcgtt gaactccacc ggaagcgccg agccgaccgt
    10681 ctcctccagg gacttgcccg aacccttctc cggggtcacg tgcagcatcg cgaagtcgta
    10741 cggggcaccc gcgccaccgg tgggaccgcc cgtcgcgatc cactggtccg aggtctgcgc
    10801 ccagtcgctc caccacacgc cgaacggggc cacctgctcg cggggcgcgc ccttgagcgc
    10861 ggtcgccggc ttgcctgcgt tgttgtagga cgggacgaag gcgatgttgc ggtaccagcc
    10921 gccggacttg cccgagtgca cgcagtggcc cgccgtccag accatgttgg acttgcccgg
    10981 gtgcgcgggg tccttgacca cggtggccga gcagaccatc gagccctcgg ggccgtcgaa
    11041 gaagaccttg ccggactccg gaacgttcgc gtggtacggg gcgggcgcgg gcttggccgc
    11101 caccgcggcc ggcgtcgggt ccgtcacacc ctggtccttg ccggcgtccg ggtccacgga
    11161 cgggcccttc ggctcctcgg cgccacgcat ccggtccggg tcccacaggt cctcgatgat
    11221 cgggttgacg tagtcacccg cctcgcggag ccagtcgtcc tggttccagt tcttccacgc
    11281 accgcccctc cacttctcca ggtcgaagcc gtgctccttg agcttgtcct tgagctcgtc
    11341 cgggatcttg atcccgtcgg ctccggaggg aaggctcgcc gctacggtcg gcttggcgtc
    11401 gccgccggcc tccccgtcgc ccgggccgca ggccgcggcg gtcagcgcga gagcggccgc
    11461 gcaaagggcc gctgtgaccg gtcggttcgg tcgcatgtcg taagtccccc tggtgggtcg
    11521 aggcgttcgt tgcagtggag cgcagcaccc cactatgccg atgccgttgg ggacggcgca
    11581 gaccggggcg cggttcctgc cggacgggtg tccggtgccg acacggagag caaggatctt
    11641 gggcccaccc gtgatccgtt gccttccccg tcgttgctac atacggggga aagggcggca
    11701 gcgttcatgt tcgaggcgca atccggaaga gaagccggca gcgaattccg tgcgggaggt
    11761 ccgacactcg tggctctgac cgaacaggcc gcagccgcgg cgaccgttgt gacacagggg
    11821 agcaggggct ccgcggccgc cgcggaaggg atcctgggcc ggcaggcgca gcgggaatcc
    11881 gccgcccgga cgtacgcgcg ctccctgccg atcgttccgg tacgggcccg gggcctgacg
    11941 atcgagggcg ccgacgggcg ccgctacctg gactgcctct cgggcgccgg aaccctcgcg
    12001 ctggggcaca accacccggt ggtgctcgaa gcgatccggg gcgtgctcga ctccggagcc
    12061 ccgctgcacg tgctggacct cgcgaccccg gtcaaggacg ccttcaccag cgagctgttc
    12121 gcgaacctgc cggccgggct ggccgccgac gcccgcatcc agttctgcgg gccggccggg
    12181 accgatgccg tcgaggccgc gctgaaactc gtgcgcaccg ccaccgggcg ctccgggctg
    12241 ctcgccttca ccggggccta ccacggcatg accgccgggg cgctggacgc ctccgggggc
    12301 gctcccgagg tacgggtgac gcggcttccg tacccgcagg actaccgctg ccccttcggg
    12361 gtcggcgggg ccgagggcgc gcggctcgcg gcccggtgga cggagagcct gctggacgac
    12421 cccaagagcg gagtgccgtc gcccgccgcg atgatcgtcg agcccgtgca gggcgagggc
    12481 ggggtcatcc cctccccgga cgcgtggctg cgacggatgc gggagatcac cgcggcgcgg
    12541 gggatcccgc tgatcgcgga cgaggtgcag acgggggtcg gccgcaccgg cgccttctgg
    12601 ggcgtcgacc acgccggggt ggtgcccgat gtgatggtcc tgtccaaggc gatcggcggc
    12661 agcctgccgc tggcggtgat cgtgtaccgg gcggagctgg acgtctgggc gcccggtgcc
    12721 cacgccggca ccttccgcgg caaccagctg gccatggcgg cgggcaccgc gacgctggcg
    12781 tacgtccgcg agaacggcct cgccgagcgc gcggcgaccc tgggcgaccg gatgctcgcg
    12841 gccttgcgcg ggctgatccc ggcccatccg tgcgtcgggg acgtccgggg ccggggcctg
    12901 atgatcggcg tcgagctcat cgaccccgac accggcgccg ccgcccccgg cctcgcgtcc
    12961 gccgtccgcc gggagtgcct ggaccgcggc ctgatcgtgg aactcggcgg ccgccactcc
    13021 agcgtcgtcc gcctgctgcc cccgctgacc gtgacggacg aacaggccac cgccgtcctc
    13081 gaccgcctcg ccgacgccat ccccgcagcc ggccgccgcc cccactgacc cgcacccgaa
    13141 ggacccccat gcccgacacc ccctccccac ccccgacccc cgagccgccc gcccaactcc
    13201 ccgtgcccga gcgttccccg cacttcaccg cggctccgac cccggcctcg gcctcggcag
    13261 cgttcatgcc gacggcggcc gcggcccccg agacgcctgc ccagccccca ggggctgaga
    13321 gctgcccgtc tcccaccccg gccccggccc cgacctcggt tccggccccg gttccggccg
    13381 cgacctcgac cccggcccca atctcggact cggtcccgac ctcggccgtg gctgctgcgc
    13441 cagccatgca gacggcggcc gcggcgcctg agcgggcggc ccagccccaa gcgtctgagc
    13501 atccgccgca cctcaccgcg gcctcgggca cgggcgaggg catggcgacg gcggccacgg
    13561 ctcctgagcc ggccgtccag tcctcgttgg gcgtgcgctt gcccgccggg gaccggggcc
    13621 tgtccgccca gggcatggac ccaggcacgc ctacgggggc ggtagtcccc ggcccggtcg
    13681 ctcaggctgc gccgggcgcg agctcggccg acggtgactc cggcccttct gcccgggaca
    13741 tggagcccgc gcacctggct gcggaggctg ccgcccacgg gccgatcgca ctcgtctccc
    13801 cgagcggaca ctcgactgct ggggatgacg gctccttcac cccgggcccg gagtccgcgt
    13861 ggctcgcgga cccgggcatg gcgccgggcg acgccgcttc cctacatggc agggagggcg
    13921 gcgtacggtc cccgatcacg gagtccgccc cgggccccgg gcagccgcag ctcccgggtg
    13981 cggccccgga ggcacccggc atgccgggcc ggtcggaggc gtcgagcctg tccccggccc
    14041 gggacgccga ggactggacg gtcggcgtgc ccgcgccgca gttcgggccg gccggcttcc
    14101 ccgcctcggg gttgccggga ggttggcccg gtgccgccga ggcgggggcg tccgcgtacg
    14161 gcggctccga ggcggctgac cttccgggtt cgggcacgcc cggcccggcc ccggccccgc
    14221 ggagcgaccc ggcggccagt gtgccccggc agaaggacgg cacggggaga gcccgggtgg
    14281 gcggggccgg acccctcggc cccgaaccgg ccgcgttgcc cgacctcctg gaccaccccg
    14341 acccggccgt cgccgccgag gccgcggcgg tggagaacct gctgcggtgc tgggtccgcg
    14401 aaaccggtat cgggcgtccc gacgggcccg tcggaaccct gctccgcatc cccctccccg
    14461 cctccggcgc cgccctgctc gtcgccgtcc gctactggtc cccgtccggc tggcaccggt
    14521 tctccccgcc ccggttcgag gccgcgcccg cccacgcccc cgccctggac gccgtcaccc
    14581 tcgccgccct gatcgcccgc gagggcaacc ccgccagccg cggcggcgcc gacctcgtcg
    14641 gccgggtctc cgactcggtg caccgcaccg ccgagttcat cgccgaccgg cgcgaacacc
    14701 cctccccgcc cgcccccgtg gccggggacc tcttcctcac ctccgaacag tcgctccttc
    14761 tcggtcaccc cctgcacccc accccgaaga gccgcgaagg cctctccgaa gccgaggtgc
    14821 gcccgtactc acccgaactc cacggctcct tccccctcca ctggctggcg gtcgcacccg
    14881 ccgccctcgc caccgactcc gcctggaccg aacgcggccg ccccgtcccc gccgcgcagc
    14941 tcctcggccg gctcgccccc ggactcacgc tccccgacgg cgccaccccc cttcccctcc
    15001 acccctggca ggcccgcgac ctgctccggc gccccgccgt caccgccctg cgcgacgcgg
    15061 gactcctcac cgacctcggc ccgcacggcg agccctggca ccccacctcc tccatccgca
    15121 ccgtccaccg ccccggcgcc cccgcgatgc tcaagctctc cctgggcctg cgcatcacca
    15181 actcccgccg cgagaacctc cgcaaggaac tccaccgcgg tgtcgaggtg caccggctgc
    15241 tccgcaccgg cctcgcagag cagtggcagg cggcccaccc cggcttcgac atcgtccgcg
    15301 accccgcctg ggtcgccgtc aacgccccgg acggcacccc cgtccaagga ctcgacgtcc
    15361 tgctgcgcca caaccccttc cgctccggcg acgacgccct ctgcgtcgcc gcgctcaccg
    15421 ccccccgccc gtggcccggc cggaccacga tgcgctcccg gctcgccgag atcgtctccc
    15481 gcctcgccgg cgccaccggc cgctccactt cggccgtctc cgccgagtgg ttcctgcgct
    15541 acctcgacca cgtcgtcctg ccggtgctgg cgttcgacgc gctcgccggt gtggccctcg
    15601 aagcgcacca gcagaacacc ctggtgatcc tcgaccccgc cggctggccc ctcggcggcc
    15661 gctaccgaga caaccagggc tactacttcc gcgcctcccg ccgcacggaa ctggagcgcc
    15721 ggctccccgg catcggcgcc gccagcgaca ccttcgtctc cgacgccatc accgacgaac
    15781 gcttcgcgta ctacctcggc gtcaacaacg tgctcggtct catcggggcc ttcggatccg
    15841 cgcggctcgc cgacgagcgc gtgctcctcg ccgccttccg ccgcttcctc ggcaaagccg
    15901 caggtctcgg cccgctcccc gcgcaattgc tggactcgcc caccctgcgc tgcaaggcga
    15961 acctgctcac ccgcctgggc ggcctcgacg agctggtcgg ccccgtcgac acccagtccg
    16021 tgtacgtcac catcgccaac ccccttcacg attgacgcgt caccaccgac gcggagaaga
    16081 gcaccgatgc cctccaccga cgaaaccgtc gaacttcgcc tcaacgcaca gctgctgccc
    16141 ctgctcgccg aggccgacct gctggactcc ccggccgcct gggggagcgc caccaccgcc
    16201 gcgggagcct tccgcctcga acccgtacgg ctcgaacgcg acctggaact cctcacgcgc
    16261 tggatgaacg accccgaggt ggccgcctac tgggaactcg gcggcccggc cgccgtcacg
    16321 gccgcccacc tacgggcgca gctcgacggc gacggccgca gcatcccctg cctcggtctc
    16381 ctcgacggca cgccgatgag ctactgggag atctaccggg ccgacctcga cccgctgtcc
    16441 cgccactacc cggcgcgccc ccacgacacg ggtatccacc tgctcgtcgg agacggcacg
    16501 aaccgcggcc gcggcctggg caccgcactg ctgcgcgccg tagccgacct ggtcttcgac
    16561 aaccggccgc gctgcacccg cgtcatcgcc gaaccggaca tccgcaacac cccctccgtg
    16621 acagccttcc tgaactctgg cttccgttgt cccgcggaga tcgacctccc cgagaagcgc
    16681 gccgcgctga tgatccggga acgggcgctg cgcaatctcc tctgagtgcc gcccccgcag
    16741 tcccgcaccg gctccggccc gcctccccgc ctgccgctct ccgcgtcctt cctcatacct
    16801 ctccacttga taactctgcg tgacgaagca aggttcccga tctcccgagg agtcccgtgc
    16861 cgaatttccc cgcagctcac gacttcacgg aaaccaccgt ggccccgtca ccccagcacc
    16921 cttgcacgcc gcccgaaatc aaccccgtga cctgggcctt cgccggccgc gcgctcctcg
    16981 ccaagatgct cggcgagttc gcgtacgagg ggatcatcag ccccgtcccg gccccggccc
    17041 cggccgccgg tgacgcctgg accctcaccc tcgatgacgg cagcagcctc ggcttccgtg
    17101 cccgccgccg ctcgtacggc agctggcagg tcacccccga caccctgacc ctcaccccgg
    17161 cgccgccctc ctacggcagc ccgacccccg ccggccaccc gaccgccttc ggggacccgt
    17221 acgccttcct catccgcgcc cgctccctcc tcggcctcga cggcgcgacc ctcggccacc
    17281 tcgtccgcga gctcagcgcc accctcaccg ccgacgcccg catcgcccac accgcgctca
    17341 ccgccgacgt cctcgccgac ctcgactacg ccgagctcga aggccaccag accgggcacc
    17401 cctggctcgt cctcaacaag gggcgcatcg gtctctccgc cgccgacacc gccgcctggg
    17461 cccccgaggc ccgcacccgc cagcgcctgc cctggctcgc cgcgcacacc tcgctcgccg
    17521 agtaccgcgg cacggccggc ctcgaagacc ccgcgcgcct ctaccgcgcc gaactcgacc
    17581 ccgtcacccg cgccgccttc gaccaggccc tgcgcgaccg gggcctcgac cccagcggct
    17641 acctctacct ccccgtccac ccctggcagt gggacgaggt cgtgctgccg ctgttcgccc
    17701 aggccctcgc ctccggggcg ctggtcccgc tgcccgccga tcccgacgta cgcctgcccc
    17761 agcagtccat ccgtacgttc ctcaacctca cccgccccga ccgccacagc gtcaaactgc
    17821 cgctctccgt cttcaacacc atggtctggc gcggcctgcc ctccgacctc gccctcgccg
    17881 cccccgccgt cacctcctgg atccactccc tccgcgacgc ggaccccttc ctgcgcgacg
    17941 aatgccgggt ggtcctgctc ggcgaggtcg cctccgtcac cgtccgccac ccggtctacg
    18001 agcagctgcc cgaggtcccg taccagtaca aggagctcct cggggcgatc tggcgcgagc
    18061 ccctcaccgg ccacctcgcc cccggcgagc gcgcccgcac cctcgcctcc ctcctccaca
    18121 ccgacccgcg cggccgctcc ttcaccgccg aactcgtcgc ccggtccgga ctcgccccca
    18181 ccgtctggct ccagcggctc ttcgccgccc tgctgccccc gctgctccgc ttcctctacc
    18241 gctacggcac cgtcttctcc ccgcacggcg agaacgcgat cgtgatcttc gacgagcagg
    18301 acgtgccggt ccggctcgcg gtcaaggact tcgtcgacga cgtcaacatc agccgcgagc
    18361 cgctgcccga gcacgcctcc atgcccgccg aggtccgcgc cgccctgctc accgagccgc
    18421 ccgccttcct tacccagttc atccactccg ggctgttcat cggcgtcttc cgctacctct
    18481 gcgccctgtg cgaggaccgg ctcggcgtcc cggagatcga gttctggtcc ctcgtacggg
    18541 ccgagatcct ccgccaccag gcgcgtttcc cagagctcaa ggagcggtac gagctcttcg
    18601 acctgctcac cgagcggatc gaccggctct gcctgaaccg gaaccggctc cacgaggacg
    18661 gctaccgcga ccgtcccgac cgcccgcacg ccgtcaccca cggcaccgtg cccaacccgc
    18721 tgtaccagcc gtgattgctc gtcgatgcgg tcgctgtcgg tgcggcccct tagggttggc
    18781 agtgctatga cgaagccctc cctccccgac ctgctgcacg ccgccgtctc cgccgtcggc
    18841 ggcacggagc ggcccggcca ggtagccatg gccgaagccg tgggcgaagc gatcgacgac
    18901 aactcccacc ggctgatcca ggccggcacc ggcaccggca agtccctcgg ctacctggtg
    18961 cctgccctcg cgcacggcga gcgcgtggtc gtggcgaccg cgacgctggc cctgcagcgg
    19021 cagctcgtcg agcgcgacct gccgcgcacg gtggaggcgc tgcacccgca gctgcgccgc
    19081 cgcccgcagt tcgccatgct caagggccgc tccaactacc tgtgcctcca ccggctgcac
    19141 gagggagccc cgcaggacga ggaggaaggc ctcttcgacc agttcgaggc ggccaccccc
    19201 accagcaagc tcggcaagga cctgctgcgc ctgcgcgact gggcggacga gaccgagacc
    19261 ggcgaccggg acgacctgac cccgggcgtc tcggacaagg cctgggcgca gatctcggtc
    19321 tcctcccggg aatgcctggg cgccacgaag tgcgcgtacg gggccgagtg cttcgccgag
    19381 gccgcccgcg agcgggccaa gctcgccgat gtcgtcgtca ccaaccacgc gctgctcgcc
    19441 atcgacgcca tcgagggcgc ccccgtgctc ccgcagcacg aggtgctgat cgtggacgag
    19501 gcgcacgagc tggtctcccg ggtgaccggg gtcgccaccg gtgagctcac ccccggccag
    19561 gtcaaccgtg ccgtcaagcg ggcggccaag ctggtcgacg agaagagcgc ggactccctg
    19621 cagaccgcct ccgagtcctt cgagcgggtc atggagctgg cgctcccggg ccggctggag
    19681 gagatcccgg aggacctcgg ctacgcgctg atggccctgc gggacgccgc gcgcaatgtc
    19741 atctcggcga tcggctccac ccgcgacaag tccgtccacg acgaggacgc cgtccgcaag
    19801 caggcgctcg ccgccgtgga caacatccac accgtggccg agcggatcac caacggctcc
    19861 gagtacgacg tcgtctggta cgagcgccac gaccggttcg gcgccaccct ccgggtcgcc
    19921 ccgctgtccg tgtccgggct gctcagggag aagctgttcg aggaccgctc ggtggtcctc
    19981 acctccgcca ccctcaagct gggcggcgac ttcaacggtg tcgcggcctc gctgggcctg
    20041 tcccccgagg gtgtcgaggg ggatgacgtc ccggtctgga agggcctgga cgtcggctcc
    20101 ccgttcgact acccgaagca gggcatcctg tacgtcgcca agcacctggc cacgccgggc
    20161 cgcgagggca cccgcggcga catgatggac gagctcgccg agctgatcga ggcggccggc
    20221 ggccgtactc tcggactctt ctcttccatg cgcggcgcca aggcggccgc cgaggaactg
    20281 cgcggccggc tcgacaaccc gatcctgctc cagggtgagg agacgctggg cgagctgatc
    20341 aaggccttcg ccgcggatcc gaagacctgc ctgttcggca cgctctcgct ctggcagggc
    20401 gtggacgtgc ccggcccgag ctgccagctg gtggtcatgg accggatccc gttcccgcgc
    20461 ccggacgacc cgctgatgag cgcccggcag aagtcggtcg aggagcacgg cggcaacggc
    20521 ttcatggccg tcgcggccac ccatgcggcg ctgctgatgg cgcagggcgc gggccggctg
    20581 gtacgggcct ccggcgaccg gggtgtcgtg gccgtgctgg acccccggct ggccacggcc
    20641 cggtacggga gcttcctacg ggccacgctg ccggacttct ggtacaccac ggaccgtaac
    20701 caggcccgtc gctcactggc cgccatcgac gccggcgccc aggccgaggg caagtagccc
    20761 agccgcaaaa agacgacagc tccgggaccg gcgcagtagg tcccggagct ggatgggggc
    20821 gcgggctctc agacccggcg cagtaccgcg acgaccttgc cgaggatggt cgcctcgtcg
    20881 ccggggatcg gctggtacgc ggcgttgtgc gggaggagcc agacatggcc gtcctcgcgc
    20941 ttgaagcgct tgacggtggc ctcgccgtcc agcatcgcgg cgacgatgtc gccgttctcc
    21001 gcgacgggct ggcggcggac cgtgacccag tcgccgtcac agatggccgc ctcgatcatc
    21061 gagtcgccga cgaccttgag gacgaagagc tcaccgtcac cgacgagctg gcgggggagc
    21121 gggaacacgt cctccaccga ctcctcggcg aggatcgggc cgccggccgc gatccggccg
    21181 accaggggaa cgtaggaggc ggcgggcttg cccgtggtgt ccgtgggctg cgagctcggc
    21241 tggtcggagc cgcgcacctc gtacgcccgg gggcggtgcg ggtcgcggcg caggaagccc
    21301 ttgcgctcca gggccatcag ctggtgcgcg accgacgacg tgctcgacag gccgaccgcc
    21361 tggccgatct cccgcatcga cggcgggtaa ccccgccgct gcacggagtc ccgaatgacc
    21421 tcgatgaccc tccgctgccg gtccgtgagt cccgagctgt cggcgcggat gcctggaggg
    21481 cgacctggca gcgagcgggc ggggcgtacg ggctccgcct ccgggttcag gcttgcgtcg
    21541 ttcatggcat gcaccggctc aagtcggctc tgggagcggt tctgggcagt gatggtggcg
    21601 gcactgtctg cggtggtggt cacgtcggcc cctctcgaaa tgttctccct agctggacaa
    21661 cggtagttgc tttcgaaagg ttgcgccaaa cacacgttcg agtgaaaaat cgcagatcgc
    21721 tcgtcgtggt cacagcgtga ggtgtatgga caatcggtcc gccgaacgcg ggttcggacc
    21781 cggctctgct gcttacggta cccttccgcg tcgggccgcc gccgtgccgg cagtggccag
    21841 tgtggcaccg gcgagccagg aatccggccg tcgggcgccg cgacacgcgg tgcgccagaa
    21901 tccaccacaa cccaagatct agtggttgga tgggcgctgc cacccagagg ttgtggttcc
    21961 tcggtcaatc gagggccgtg acatcgcata tgcttgtggc tgcttcacgg gtccccggca
    22021 gagtctcctc tctaccgctc agggacgccg tggggtgatt cagtcgtgcc aagagggagg
    22081 gtgagggaac catgcactgc cccttctgca ggcaccccga cagccgtgtc gtcgacagcc
    22141 gcaccacgga cgacggcacg tcgattcgtc ggcgccgtca gtgccccgac tgctcccgtc
    22201 gtttcacgac ggtggagacg gcctcgctga tggtgatcaa gcgcagtggg gtcaccgaac
    22261 cctttagccg caccaaggtc atctctggcg tccgcaaggc gtgccaggga cggccggtca
    22321 ccgaggacgc cctcgccaaa ctcggccagc gggtcgagga ggcggtgcgc gccaccggga
    22381 gtgccgagct gaccacccat gacgtgggtc tggccatact cggccccttg caggagctcg
    22441 atctcgtcgc ctacctgcgc ttcgcatccg tgtacaaagc gttcgacacc cttgaagact
    22501 tcgagaccgc catcgcggaa ctccgtgtgc cgcggtctca ccccgatgag tgcgagcagg
    22561 gtggggccgc ccaggtcccc gtgcccgcct ccgccgccga ctgatcggac ggccgcagcg
    22621 cagcgcggtc cgtctgctcg gccaggcgaa gagacgtaga tacaagacac agcaccgtgc
    22681 ctcggaataa cgctggcact ttagggcgtt tttgcccgca tatgggaggc ggcatgacag
    22741 agacggcgag cggctcggca cgaggttccc gcgccaaggg gaccaaggct gccaagggcg
    22801 gcctgcgtat cgagcgcatc cacaccaccc cgggcgtgca cccttacgac gaggtgagct
    22861 gggagcgccg tgacgtcgtc atgaccaact ggcgcgacgg ctcggtcaac ttcgagcagc
    22921 gtggcgtcga gttccccgac ttctggtcgg tgaacgcggt caacatcgtc accagcaagt
    22981 acttccgcgg cgcggtcggc accccgcagc gtgagaccgg tctgaagcag ctgatcgacc
    23041 ggatcgtgaa gacctacacg aaggccggcg aggacttcga ctacttcgcc tcgcccgccg
    23101 acgtggagat cttcgagcac gagctgacgt acgcgctcct gcaccagatc ttcagcttca
    23161 actcgccggt gtggttcaac gtcggcacgc cccagccgca gcaggtctcc gcctgcttca
    23221 tcctgtccgt cgacgactcc atggagtcga tcctcgactg gtacaaggaa gagggcatga
    23281 tcttcaaggg cggctccggc gccggcctga acctctcccg catccgttcc tccaaggagc
    23341 tcctctcctc cggcggcaac gcctccggcc cggtctcctt catgcgcggc gccgacgcct
    23401 ccgccggaac gatcaagtcg ggcggcgcca cccgccgcgc ggccaagatg gtcgtcctgg
    23461 acgtggacca cccggacgtc gaggccttca tcgagaccaa ggtgaaggaa gaggagaaga
    23521 tccgcgccct gcgcgacgcg ggcttcgaca tggacctggg cggcgacgac atcacgtccg
    23581 tccagtacca gaacgccaac aactccgtcc gtgtgaacga cgagttcatg acggccgtcg
    23641 agaacggcac cgagttcggc ctgcgttccc gcatgaccgg cgaggtcatc gagaaggtcg
    23701 acgccaaggc gctcttccgc aagctcgccg aggcggcgtg ggcctgcgcg gacccgggca
    23761 tccagtacga cggtgtgatc aacaactggc acacctgccc ggagtccggc cgcatcaccg
    23821 cgtccaaccc ctgcagcgag tacatgcacc tggacaacac gtcctgcaac ctcgcctcgc
    23881 tgaacctgat gaagttcctg aacgacgacg gcaagggcaa ccagtccttc gacgccgagc
    23941 gcttcgccaa ggtcgtcgag ctcgtcatca ccgcgatgga catctccatc tgcttcgcgg
    24001 acttcccgac gcagaagatc ggcgagaaca cccgcgcctt ccgtcagctg ggcatcggct
    24061 acgccaacct cggcgccctg ctgatggcca ccggtcacgc gtacgactct gacggcggcc
    24121 gcaccctcgc cgcgtcgatc acctcgctga tgaccggtac cgcgtacaag cgctccgccg
    24181 agctggccgc catcgtcggc ccgtacgacg gctacgcccg caacgccgac gcccacaagc
    24241 gcgtcatgaa gcagcacgcc gacgccaacg ccaccgcgcc gcgcacccag gacctggaca
    24301 acaccatctg ggccgctgcc accgaggcct ggcaggacgt cctgcgcctc ggcgagaaga
    24361 acggcttccg caactcccag gcctccgtcc tcgcgccgac cggcaccatc ggtctcgcga
    24421 tgtcctgcga caccacgggt gtcgagccgg acctggccct ggtcaagttc aagaagctcg
    24481 tcggcggcgg ctcgatgcag atcgtcaacg gcaccgtccc gcaggccctg cgccgcctgg
    24541 gttaccagga ggagcagatc gaggcgatcg tcacccacat cgccgagcac ggcgtcgtgg
    24601 tcgacgcccc gggcctgaag accgagcact acgaggtctt cgactgcgcc atgggcgagc
    24661 gttccatttc cgcgatgggc cacgtccgca tgatggccgc gatccagccc tggatctcgg
    24721 gcgcgatctc gaagacggtc aacatgccgg agacggcgac cgtcgaggag atcgaggaga
    24781 tctacttcga ggcgtggaag atgggcgtca aggcgctcgc gatctaccgc gacaactgca
    24841 aggtcggcca gcccctctcc gccaagaaga aggaagagga gaaggaggag gtcaccgcca
    24901 agacggagga gaccatccgc gccgccgtcg agaaggtcat cgagtaccgt cccgtccgca
    24961 agcgcctccc caagggccgc ccgggcatca ccacctcctt caccgtgggt ggcgccgagg
    25021 gctacatgac cgccaactcc tacccggacg acggtctcgg cgaggtcttc ctgaagatgt
    25081 ccaagcaggg ttccaccctc gcgggcatga tggacgcctt ctcgatcgcc gtctcggtcg
    25141 gtctgcagta cggcgtgccg ctggagacct acgtctcgaa gttcacgaac atgcgcttcg
    25201 agccggccgg catgacggac gacccggacg tgcggatggc gcagtcgatc gtcgactaca
    25261 tcttccgtcg cctggcgctg gacttcctgc ccttcgagac ccgctcggcg ctcggcatcc
    25321 acaccgccga cgagcgtcag cgtcacctcg acaccgggtc gtacgagccg ctggacgagg
    25381 agatcgacac ggagtccctg agccagtcgg ctccgctgac cgcggtcccg gccccgaagc
    25441 ccatggcggt catcgaggtc ccggccccga agacggcgca ctccagcgcc gaactggtcg
    25501 agatgcagct cggcgtctcc gccgacgccc cgctctgctt ctcctgcggt acgaagatgc
    25561 agcgcgccgg ctcctgctac atctgcgagg gctgcggctc caccagcggc tgcagctgag
    25621 cgactgagtg actgacggag cggggaccgg ccacgggccg gtccccgctc cggcgtctgc
    25681 ccgggtcacc gccgccgggc aaaaggcctt gtgcctgcgg ggacggctcc ggcacgctca
    25741 cctgcgacga gaacggcagg ggtgggggac gtggcagacg gtttcgccgg atccaagaag
    25801 gaaatgaacg tgggggccca ggcggtcgcg gcggtggtgg cggtcggggg cgtcctgggg
    25861 ggcgcgtggg ggctggggga attcttcgag ctggggcact cgcccgagga cgtcaaaccg
    25921 gccgtctgct cgaccacgaa ggacgagctg cccgcggaat acgcctccgg ggcgaagctg
    25981 tgcgcggccc tgaaccgccc cgacctgccg gcgctcctcg gaacgcccgc ggagcagccg
    26041 ctgaacgcca cgggcaacgg gaggtggatc accttcggca gcggcgtcaa gatcgccgca
    26101 tccgaggcga aggtccagct gaagacccac accgtgcagg tttcggcgtc ctacgacgac
    26161 ctcccggtcg accaggcggt cgaggtcctg ggcgtgaccg cccaacagca gacggtcctg
    26221 gggcacccgg ccgtcgtcta ctcgtacccg accatcgcca tcacctttga cttcggcaac
    26281 ggcaagaccg gcagcgggcc cggcggcatc gcccgccacg tcatggtcgc cgccgacgcg
    26341 aagggcggcg gcgggacctc cttcgacgtg gtcgtctggc gtgaggacgg cacgctgccc
    26401 gatgacatgg cgctgctccg cgtcgccgag caggtgctgc cgacggtccc ggggtggagc
    26461 gccggctgat ggagggggcg ccggccggcc tggggcccgc cgggcggggc acagggtggg
    26521 cgggaaagcc ggttggagag ggaggtcttc gagccgatca tggtgggcag cgggacgctt
    26581 gagcacccgc ggtcgtgtga gcgggagcgg gggagacatg tggagcggtg acgagctgga
    26641 tctggacgcc tatctggcgc ggatcgggta cgacggaccc gtcggggacg acggggaact
    26701 caaggcggac ctcgcgacgt tgtacgcggt gcaccgggcg cacaccgccg ccatcacctt
    26761 cgagagcctg gacgtcctgc tcggccgccc cgtcgctctg gacatcgagg cccttcagga
    26821 caagatcgtg cagggccgtc gcggcggcta ctgctacgag cagaactcgc tgctggccgc
    26881 cgccctggag cggatcggct tcgaggtctc cgggcgcggt gcccgcaacc gcacccgagg
    26941 ggacaccctg ctggcggtga cgcacgccgt cctcgtcgtc accgtcgacg gtgaaccctg
    27001 gctgtgcgat gccgggttcg gatatctggg gccgcgcgag cccgtcccgc tggcgcgccc
    27061 cggggccgaa atccggcagg gggcatggac gtacaccgtc cgcgaggagg acggcggtgt
    27121 cctcgcgctg tgcctgcggc gcgagggaac ctggcgcgag ctgtacgcgt tctccccgca
    27181 gcactaccac cccgtcgact acgtggtgct gaaccactac agctcctcgc acccccgctc
    27241 cgccttcatc gggcaggtca tcgtccagct cccgggcgac gccgtccggc tggccctcgt
    27301 cgggcgggaa ctcacccgcc tgtaccccga cgggcgcacg gaacggcagc cggtggagcc
    27361 cggcgaactg gtgccactgc tcgcccggga gttcgggctt cggctgtccg agcgggatgc
    27421 ggcggaactg gtcctgatca accgcgccga ggactgaccg gggcagcgtc gggcccgtac
    27481 gatggcgcgg tgctggtcaa gtggattcgc tgcacggtga cggaccgacg cggcttcgag
    27541 cgcgggcagc gcaaatgggc ggggcttccc ggcgagccgg gattccgggg gcagggcggt
    27601 ggctggagcc gagggcgaca gggggtggcg catgtcttca cgttctggga gagccgttcc
    27661 ttctacgact ccttcatggc gcgctcgcac gaccggctgg ccgcttccca gaacggcacc
    27721 tacaccgcga tgcgggtcac cctctttgat caccgcttcg acgtgaagac gggcttcgag
    27781 ccgcgcttca ccgacgccga cgtggtgcgc gtcgcacaca cccgggtacg ggaggggcgc
    27841 gtggaccact tcgcccacat gcaggagaag gtgtggaacc cggccatggc gggctcgccc
    27901 ggcatgatcc gcggcctctt cggggaggcc cccggccggg agttcctcgt cctgtcgatg
    27961 tggcgcgcgg ccgccgagca cggcaagtac cgtccggagc gggtcgaacg cctctcgctg
    28021 cgcgcccaga ccgaagccga cgtggaggcc ctcacgggtg acgtcgtcga cctcgaaccg
    28081 tcctggacgg tatgaccgta cgacggtagg cgccgagccg gcccgaccgg cgtgcccggg
    28141 tgttcgctcc accgggtgcc gcatagggtc ggggaatggc acgaccacgg cgcatcgtcc
    28201 tcgtccgaca cggggaatcg gagggcaacc tcgatgacac ggtgtacgag cgggagcccg
    28261 accacgccct gcgcctgacc ccggccgggc gcgcgcaggc cgccgagacc ggcgtacggc
    28321 tgcgcgagct gttcggcgac gagaccatca gcgcgtacct ctccccctac cgccggaccc
    28381 tgcagacctt ccgggaactg cgcctggacc cggtgcgcgt ccgggcgcgc gaggagccca
    28441 ggctgcgcga acaggactgg ggaaactggc aggaccgcga cgacgtccgg ctccagaagg
    28501 cctaccgcga cgcctacggc cacttcttct accggttcgc gcagggtgag tcgggagcgg
    28561 acgtgtacga ccgggtcggt tccttcctgg agagcctcta ccgcagtttc gaggcaccgg
    28621 accacccgga gaacgtgctg ctggtgacgc acgggctgac gatgcggctg ttctgcatgc
    28681 gctggttcca ctggtcggtg gccgagttcg aggcattgtc caacccgggg aacggcgagt
    28741 accgggtgct gctgcggggg ccggacggcc ggtaccggat ggaccgcccg tttgagcgct
    28801 ggaccacacc cgagccttat gacctggacg gctagagtga cgcgggatga cctctgactc
    28861 ctcttccgaa aggcgctacg cacgcgccat ggccagcctc cgagggctgg ctctgggtga
    28921 cgccctgggc tcccagtact tcgtccccgt caactacccc ctgctcaagc gccgcgaggt
    28981 gccggcgggc aacgacacct ggcagtggac cgacgacacc gagatggcct gctcggtcgt
    29041 ggccgtcctc gccgaacacg gccgcgtcga ccaggacgcc ctcgcgctct ccttcgccca
    29101 ccaccacgac ttcgaccgcg gctacggccc tgccgtgaac cgcatgctcc gcctggtccg
    29161 cgagggcgcg gactggcgca cgctggcggc cgaactcttc aacgggcagg gctcgtgggg
    29221 caacggcgcc gccatgcgga tcgcgccgct cggcgcctgg tacgccgatg accccgagca
    29281 ggcgacccac caggcggaga tctccgccta caccacgcac cagcaccgcg aggcggtgtg
    29341 cggggcgatg gccgtcgccg ccgcggccgc gctggcggcg aacccggagg gcccgccggc
    29401 cgccgccgac ctgctggacg gggtcatcgc cctggtgccg cgcagcgcgg tgggcgccgg
    29461 gctgcggcgg gcgcgggaca tgctggacta cggcgacgcg acgacggtcg cggcggtcct
    29521 gggctgtggg cgccgcacca gcgcccacga caccgtgccg ttcgccctgt ggtcggcggc
    29581 gcgctcgctc gacgactacg agcgggcgtt ctggacgacc gcgcaggtgg gcggggacgt
    29641 cgacacgacc tgcgccatcg tcggcggggt gctgggggcg cgcggggagg cggtgctgcc
    29701 ggaggcctgg ctggcccgca ccgagacgct gccggcctgg ctgccggagt ccgcgcggcg
    29761 ctgacacctc ggcgctgacg ccacgcccgg gccggggcgc cgtacccggc tctggtttgt
    29821 cacggtcctg ccacaggggt cccgtgcggc tggccaaagc cgcacgtcac aggcctaccc
    29881 tgtccgcttc gccgcctcca gtggaaccag tggggcggcc gacaggggag gggaacccga
    29941 tgtcagagaa cgccgatgag gtggactccg gggcggccga gggggctgtg gccggagggg
    30001 ctgccgttca ggggtctgcg gctcgggggg ctggggctca agggcctgcg gcccaggggt
    30061 ttgcggccca gggatctggg gctcaggggg ccgcggccga accggcgaag ccgggctcgg
    30121 cggcaccggc cgggtccggg gcgggggttg cggcgggggc cggcggcggc gcgaccgcaa
    30181 cgccggtgac cgctgcggcg gccgggggcg cgcacgccgg ggccgctgct tccgcaggtc
    30241 cggccggtgc cggtgccggt tctggcgggc cggtcggggg tggccctgcg ggcggcttcg
    30301 acgcctccgc gtggcaagcc cggcaggcgc tgatccagca gcagcgcgcc cgggccgccg
    30361 cgcccgcggc ctgggcggta cggatccgcc ccgtcgaggc ggccccgatc cggaccgcca
    30421 cgctcatcgc cgctgtgctc gccggcctcg ccgccgccct gttgctgggc gacggtatgg
    30481 gccccggcct gctggtcgcc gtactgcccg cgatcgccgc cgcctacttc gccgcccgcg
    30541 ccgccggccg caaggcccgc ccgtggaccg tggtgtgggc cgtcggctgc gtggccctgc
    30601 tcgtcgtgcc ggcgctgcgc gactccgcct ggcccgccac gctggcgatc ctctccgccg
    30661 tctccctcgc ctcgctcgcc ctgcacggcg tccggacctg gcccggcgtg ctgttcagcc
    30721 cgttcggctt cgtcgactcc gccgtcaacg gcgtcggctg ggcctggacc ggcctgcgct
    30781 cccgcagcgg cgggctcagc cgggaccgct ggctgcccgt cgccaaggcg gccgccgtgg
    30841 ccctcggcct gctcgtggtc ttcggcaccc tgttcgcctc cgccgacgcc gcgttcgccg
    30901 acctgctcgg cgatctgacg cccgaggtct ccgtcggcga cgggccggtc cggatcctgc
    30961 tgttcgtcct cggcgccgtc ctcgcgctcg ccgccgcccg caccacggcg gccccgctgc
    31021 gctgggaccg gctccggatc gcccccggca gggcgcgctc ccgcctcgaa tgggcgcttc
    31081 cgctggtcgt cctcaacctg ctgttcgccg gattcaacgc cgtgcagctg gccgtcctgt
    31141 tcggcggcta cgacaaggtc ctcaagagca ccggccaccg gagctacgcc gagtacgccc
    31201 agcagggctt ctggcagctc ctctgggcca ccctgctcac cctcgtcgtg atcgcgctcg
    31261 ccctgcgctg ggcaccgcgc ggcggagccg gagaccgccg cttcgtacgc gccgtcctcg
    31321 gcaccctgtg cgcgctgacc ctggtcgtgg tcgcctccgc gctgcgccgg atggacttct
    31381 acgtggacgc gtacgggctg acccggctgc gggtgtcggt ggccgccatg gagctgtggc
    31441 tcgggctggt cctcgtactg atcatggctg ccggggtgtt cggcgcccgc tggctgcccc
    31501 gcgcggtcgc gggcagcgcg gcggcggccg tactggcctt cgggctgctg tccccggacg
    31561 gcatggtcgc cgagcggaac gtgacccgct tccagcagga cgccaagatc gacctcgcct
    31621 acttccagtc cctttcggcg gacgccgccc ccgccctaga caggctgccc gagccgcagc
    31681 gctcgtgcgc cctgcggggg atcaacgacg agctggccga ggccggcgac gtgccctggt
    31741 acgccatgag cctcggcgag taccgggccc ggaagatcct gcgcgagcgc ccgctgaagg
    31801 cctcgtacga ggactgctcg cgcctcggta cgttcggcag ccgcgtcgaa ccgtaagctc
    31861 cgggggattt ccgtacgggg ccgggtgcgc gggatcgttt ccccacgcac ccggccccgt
    31921 acgttcaggc ggccggaccc gccttcgcgg cgaccccgcc cagggcgtcc aggtcgctct
    31981 tgcgcacccg gatcatcagc acggcggtgg ccagggcgag gcccgccatg gcgacggccg
    32041 cgatgaacgc ggtggagatg ccctgggtca gcacgtggtc gccccagggg tcgggcagcc
    32101 gcccggtctc cttgaacgcg gccagctgac ccgggtcggc ccgggccatg aacgcgggca
    32161 cctgccgctc ggcgtcgtgg cgcgaggccg agccgaagac ggtgaccagg atggacagcc
    32221 ccagcgaacc accgacctgc tggctggcgt tgagcagccc cgaggccgcg cccgcctcct
    32281 gcggcgccac gcccgagacg gcggtcaggg tgagggtcac gaagttgagg cccatgccga
    32341 agccgaacag cagcatcggg ccgagcaccc cggacaggta ggaactgccg gtggtgatga
    32401 aggtcagcca ggtcagcccg gcgccggtga gggcggctcc ggtgaccatg aacggcttgg
    32461 gcccgaagcg cggcaggaag cgctgcgaga gcccggccgc cgtgatgatc gcggcggtca
    32521 cggggaggaa gccgagtccg gaccggatcg gggagaaacc cagcacgttc tgtatgaact
    32581 ggacgatgaa gaagaacatg ccgaacatcg cggccgcgag ccccagcatg atcaggtagg
    32641 tgccggcccg attgcggtcg gcgaacatcc gcagcggaat gatcggttcc tgggccttgg
    32701 cctcgacggc gacgaacagg ccgagcagga cgag
//
