LOCUS       NZ_BMVE01000001        21074 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces goshikiensis strain JCM 4640 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BMVE01000001
VERSION     NZ_BMVE01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1181871)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650555.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:30:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,491
            CDSs (total)                      :: 7,410
            Genes (coding)                    :: 7,286
            CDSs (with protein)               :: 7,286
            Genes (RNA)                       :: 81
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 44 of 125
            Pseudo Genes (incomplete)         :: 101 of 125
            Pseudo Genes (internal stop)      :: 9 of 125
            Pseudo Genes (multiple problems)  :: 27 of 125
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 486047
            Orig. end                         :: 507121
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMVE01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    417..431
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.57"
                     /tool="antismash"
     gene            446..1648
                     /locus_tag="IE248_RS02160"
                     /old_locus_tag="GCM10010336_04370"
     CDS             446..1648
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266483.1"
                     /locus_tag="IE248_RS02160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04370"
                     /product="NADP-dependent malic enzyme"
                     /protein_id="WP_008741550.1"
                     /transl_table=11
                     /translation="MAAEIVNPRSDSGTDNNPDAVFALHRGGKMAVQATVPVNDKDDLS
                     LAYTPGVAKVCTAIAENPELVHEYTWKSNVVAVVTDGTAVLGLGDIGPEASLPVMEGKA
                     ILFKQFGGVDAVPIALATKDTEEIIETVIRLAPSFGGVNLEDISAPRCFEIERRLQEAL
                     DIPIFHDDQHGTAIVTLAAMRNAAKLTGRTLGDLRAVISGAGAAGIAIAKILVDAGIGD
                     VCVTDRKGVVSADRSDLTDVKAEIAGLTNKSGLNGSLESALAGADVFIGVSGGTVPEEA
                     VASMAKDAFVFAMANPNPEVHPEVAHKYAAVVATGRSDFPNQINNVLAFPGIFAGALKV
                     RATRITEGMKIAAADAIAGVVGDELAADYVIPSPFDERVATAVSAAVAAAAKADGVARL
                     A"
     gene            2089..3051
                     /locus_tag="IE248_RS02165"
                     /old_locus_tag="GCM10010336_04390"
     CDS             2089..3051
                     /NRPS_PKS="Domain: PKS_ER (15-318). E-value: 5.4e-35.
                     Score: 112.9. Matches aSDomain:
                     nrpspksdomains_IE248_RS02165_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966331.1"
                     /locus_tag="IE248_RS02165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04390"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_008741548.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1e-20, bitscore:
                     70.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAAYAARIDRDQPLSGLELGERPAPEARPGWVTVNVKAASLNHH
                     DLWSLRGVGLGEDKLPMILGCDAAGIDQDGNEVVLHSVIGQSGHGVGPDEPRSILTERY
                     QGTFAEQVTVPAWNVLPKPAELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAG
                     GGVATAAIALGKAAGLRVFATSRDEAKRKRAVELGALEAYEPGARLPRRVDAVIETVGA
                     ATWSHSVKSLRPGGTLVISGATSGDRPAHAELTRIFFLELKVVGSTMGSKDELEDLLSF
                     CAATGVRPVIDEVLPLDRAREGFEKLASGDLFGKVVLTV"
     aSDomain        2134..3042
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE248_RS02165_PKS_ER.1"
                     /evalue="5.40E-35"
                     /label="IE248_RS02165_PKS_ER.1"
                     /locus_tag="IE248_RS02165"
                     /protein_end="318"
                     /protein_start="15"
                     /score="112.9"
                     /tool="antismash"
                     /translation="SGLELGERPAPEARPGWVTVNVKAASLNHHDLWSLRGVGLGEDKL
                     PMILGCDAAGIDQDGNEVVLHSVIGQSGHGVGPDEPRSILTERYQGTFAEQVTVPAWNV
                     LPKPAELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAGGGVATAAIALGKAAG
                     LRVFATSRDEAKRKRAVELGALEAYEPGARLPRRVDAVIETVGAATWSHSVKSLRPGGT
                     LVISGATSGDRPAHAELTRIFFLELKVVGSTMGSKDELEDLLSFCAATGVRPVIDEVLP
                     LDRAREGFEKLASGDLFGKVVL"
     CDS_motif       2479..2517
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS02165_0001"
                     /evalue="5.60E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="IE248_RS02165"
                     /protein_end="143"
                     /protein_start="130"
                     /score="13.4"
                     /tool="antismash"
                     /translation="AACLPTAWLTAYR"
     CDS_motif       2548..2607
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE248_RS02165_0002"
                     /evalue="2.80E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE248_RS02165"
                     /protein_end="173"
                     /protein_start="153"
                     /score="16.7"
                     /tool="antismash"
                     /translation="GDSVLVQGAGGGVATAAIAL"
     gene            3135..3344
                     /locus_tag="IE248_RS02170"
                     /old_locus_tag="GCM10010336_04400"
     CDS             3135..3344
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741547.1"
                     /locus_tag="IE248_RS02170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04400"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_008741547.1"
                     /transl_table=11
                     /translation="MTEATDLAERAGDRDPRVGLRAVAALRRLLEQLEAVQVRSARAQG
                     WSWQEIAAELGVSRQAVHKKHGRV"
     gene            3344..3907
                     /locus_tag="IE248_RS02175"
                     /old_locus_tag="GCM10010336_04410"
     CDS             3344..3907
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018509983.1"
                     /locus_tag="IE248_RS02175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04410"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_190029849.1"
                     /transl_table=11
                     /translation="MFERFTTAARDAVTGAVAEARRAGAATVTEEHLLLALLAQGALDP
                     LGVDRAAVAAGLARARRRGGMSRADEEALAGLGIDLTRILSRVEETHGEGALAATAPRR
                     RTLGTSLRSALGRPEPAGRHVPFAPGSKRVLEGSLRIAVGRGDRHIAAPHLLLALLSRP
                     GTVCEVLADHGVTYEAAESGLTGP"
     gene            complement(3904..4827)
                     /locus_tag="IE248_RS02180"
                     /old_locus_tag="GCM10010336_04420"
     CDS             complement(3904..4827)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947074.1"
                     /locus_tag="IE248_RS02180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04420"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_073798230.1"
                     /transl_table=11
                     /translation="MPPVFAHGRLRLYLLGLLDEAPRHGYEVIRLLEERFQGLYAPSAG
                     TVYPRLAKLEAEGLVTYATEGGRKVYSITEAGRAELADRRGELADLELEIRDSVSELAA
                     EIRADVRGAAGDLRREMRAAASATATPVEDASWAAAKEELRKAKHEWKEQARRAKDESR
                     RAREEAQQARRQAKEAQERAREEVQRIAAQFQEQFAKSGGMLGSLAGAWLGGGSAGAGS
                     GGGATGAGGAANATSATASAAAGSDWAEDLAPTADPARDLDRLLDRFRDDVRDAARDHG
                     VSPAQLAEARAHLAAAAARVTGTLRG"
     gene            complement(4829..5764)
                     /locus_tag="IE248_RS02185"
                     /old_locus_tag="GCM10010336_04430"
     CDS             complement(4829..5764)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741545.1"
                     /locus_tag="IE248_RS02185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04430"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_073798229.1"
                     /transl_table=11
                     /translation="MTEQTSTRSVAEPQKLTFDEPVAELHVRLVGGTVNVVASDEGPAR
                     LEVAAVDGPPLQVVQDGGVLTVSYEDLPWNGTRGFKEWLAAKPWKAWSAGSGDGSGRKA
                     WERSATVTLTVPAATRVQVATVSAAAFVSGIRGGTDVNGVSGDATLVGLSGRVKAHTVS
                     GSVEAQSVTGELGFHSVSGGLTVVDGAGGSVRADSVSGDMLIDLALDPAAPSPVDIFLN
                     SVSGQVAIRLPHPADARVEANTATGGVSNAFEDLRVSGQLGAKRITGTLGAGTGTLRAT
                     TVSGAIALLRRPAADAATPSAPLTLDKKVL"
     misc_feature    5763..5778
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.88"
                     /tool="antismash"
     gene            complement(6523..7455)
                     /locus_tag="IE248_RS02190"
                     /old_locus_tag="GCM10010336_04440"
     CDS             complement(6523..7455)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889347.1"
                     /locus_tag="IE248_RS02190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04440"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_037793289.1"
                     /transl_table=11
                     /translation="MELEVRHLRALCAIADAGSLHKAARQLGVSQPSLTTQLRRIERAL
                     DGELFLRERTGCRPTPFGRTVLGRARPLLAEMAALVAEARAVARGPRLRLGSTASRALP
                     GWLRRLHRRLPDTETTLVVDLSANALLRMVDSGQLDVAFVHEVEGSPLRVPAGLEMRVL
                     MEREPQFVSMSRDHPAAARAVVDLRDLARDRWTVDPSVDGEWDGLRRVFAGAGLDPPVL
                     HADYHTATSLIISGEAVAPCQPTSGPRDDMAIRPLSGDPLAVRLLLATRPGAHAEVFED
                     LRSAYREAALRTPPYRAWLHHHESPLLAA"
     gene            7663..8331
                     /gene="snpA"
                     /locus_tag="IE248_RS02195"
                     /old_locus_tag="GCM10010336_04460"
     CDS             7663..8331
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741543.1"
                     /locus_tag="IE248_RS02195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04460"
                     /product="snapalysin"
                     /protein_id="WP_008741543.1"
                     /transl_table=11
                     /translation="MRHSRTSRTAVLAATLGLGLATAVVGVAPTASAAPAPVGNAASYA
                     AYERSQENESANAAFFDAVRRSVAEQRAANPGIRAVTVTYNTRNAPSFRSQIARSTQIW
                     NSSVSNVKLQEVSSGGNFSYYEGNDSRGSYASTDGHGRGYIFLDYQQNQQYNSTRVTAH
                     ETGHVLGLPDHYSGPCSELMSGGGPGTSCQNPNPNAAERSRVNQLWANGLVGSGLGSKG
                     "
     gene            complement(8328..8537)
                     /locus_tag="IE248_RS02200"
                     /old_locus_tag="GCM10010336_04470"
     CDS             complement(8328..8537)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741542.1"
                     /locus_tag="IE248_RS02200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04470"
                     /product="hypothetical protein"
                     /protein_id="WP_008741542.1"
                     /transl_table=11
                     /translation="MTGQQRGEEQARIRVAPQAGHAQRVCPACGGSVDTVVRRRKSLGI
                     FVPEWVAGSCRNPDCPASVAPAAG"
     gene            complement(8575..9156)
                     /locus_tag="IE248_RS02205"
                     /old_locus_tag="GCM10010336_04480"
     CDS             complement(8575..9156)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741541.1"
                     /locus_tag="IE248_RS02205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04480"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_190029850.1"
                     /transl_table=11
                     /translation="MRKLTYYVGTSVDGFIADPDGDGDFLTRWTDPEYIAHMAAEFPET
                     LPTHVRALMGVGAGAAKRFDTVLMGRGTYDPALKAGITSPYAHLEQYVLSRSLTESPDP
                     AVKIFSGDAVALVRELKARPGLGIYLCGGADLAGRLADEIDEFIVKTYPVFAGSGIPMS
                     RAGFAPRGLELTGVKTFGGGQLVTTYARAL"
     gene            complement(9261..9863)
                     /locus_tag="IE248_RS02210"
                     /old_locus_tag="GCM10010336_04490"
     CDS             complement(9261..9863)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741540.1"
                     /locus_tag="IE248_RS02210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04490"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190029851.1"
                     /transl_table=11
                     /translation="MVLEIRQADQSDRDAVARLLDVAFRDDPVSGWVFPDPEHRAAVHG
                     KFLGVFVDVALEEGRIDCAVDGSAAALWLRVPAGDPDAEAAEDEVPARMRAAADPDNER
                     CELVGRLTGAVHPTAEEHEYLLMIAVAPGRQGEGLGTELMRPVLERCDREGLPAYLEAS
                     SERSKVLYERLGWEVTGEPVRLPGGPLMWPMWRKPRG"
     gene            complement(10001..11074)
                     /locus_tag="IE248_RS02215"
                     /old_locus_tag="GCM10010336_04500"
     CDS             complement(10001..11074)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741539.1"
                     /locus_tag="IE248_RS02215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04500"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_073798227.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.8e-58, bitscore:
                     192.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTETITAGEGHEAAALLERTRDAVNPELRRTVESLPGSMRRVA
                     MYHFGWEHADGTPAAGNAGKAIRPALVLAAARALRGPADTGDGDGDDGLRAVVRAAVAV
                     ELAHNFTLLHDDVIDKDVRRRGRATAWTVFGTPDAIITGDAMLALALRLLVQDGHPASA
                     AASARLATCIIELCAGQQADCAFEQRPDVSLDECLTMAMAKTGALLGCACALGALYAGA
                     GPDEVDAMDAFGREAGLAFQLIDDLIGIWGDPGHTGKPAGADLIARKKSLPVVAALTSG
                     TTAGKELAALYAGPMTGDDVHAAAAAVERAGGRDWAQAHAADRMGRAVQQLSRAVPDLA
                     AAGGLLALAEFVTRRTR"
     gene            complement(11126..12535)
                     /locus_tag="IE248_RS02220"
                     /old_locus_tag="GCM10010336_04510"
     CDS             complement(11126..12535)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741538.1"
                     /locus_tag="IE248_RS02220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04510"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_073798226.1"
                     /transl_table=11
                     /translation="MSVQAGSETEAQSPPQRSLATSAARNLATTTKSAPQMQEITSRWL
                     LKMLPWVSVQGGTYRVNRRLSYSVGDGRVEFIKTGTQVQVIPAELGELPLLRAYEDLDV
                     LTELAARCQQLDFAAGQELTSFGSPSDKVFLLAHGRIDQVGPGPYGEDAVLQTVADGAY
                     FGEDSLVDEEAIWEYTARAATSGTALVLSRQDFQLLADRVDSLRAHVESVRSLPAQRTN
                     KYGEAAIDLSAGHQGEAVLPGTFVDYEAKPREYELSIAQTVLRVHTRVADLYNQPMNQT
                     EQQLRLTVEALRERQEHEMLNNTDFGLLHNADYDQRIQPHDGVPSPDDMDQLLSMRRGS
                     KMFLAHPKAIAAFGRECNRRGLYPESIDVGGHRVPSWRGVPIFPSSKIPISDARTTSIL
                     CMRTGEEESGVVGLHQPGIPDEIEPSMSVRFMGISEQAIISYLVTAYFSAAVLVPDALG
                     VLENVEIGRWR"
     misc_feature    12724..12740
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.4"
                     /tool="antismash"
     gene            12760..13215
                     /locus_tag="IE248_RS02225"
                     /old_locus_tag="GCM10010336_04520"
     CDS             12760..13215
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741536.1"
                     /locus_tag="IE248_RS02225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04520"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_037793285.1"
                     /transl_table=11
                     /translation="MRLTRFTDLALRVLMRLAVADADLPTTRDVAATMEVPYTHSAKVV
                     ARLRHLGLIEARRGRGGGLALTAAGRAASVGGVVRELEGAGDVVDCDGAVPCPLRGACV
                     LRGALRGAQEAFFAALDPLTVNDLVAAPTGPLLLGISSGPPGRTVDP"
     gene            13343..14539
                     /locus_tag="IE248_RS02230"
                     /old_locus_tag="GCM10010336_04530"
     CDS             13343..14539
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127491.1"
                     /locus_tag="IE248_RS02230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04530"
                     /product="globin domain-containing protein"
                     /protein_id="WP_190029852.1"
                     /transl_table=11
                     /translation="MLSEKSTETVRATLPAVGAAIGDIAELFYAKLFAAHPALLRDLFN
                     RGNQNSGAQKQALAGSIAAFATHLLTHPGTRPDVMLNRIAHKHASLGITREQYEIVHHH
                     LFEAIAEILGEAVTPEVAEAWDEVYWLMAGALVAIEDRLYAQRQVLAGDVWRDWRIAAR
                     FEETADCATFHLVPADGAPAPAFAPGQYVSVQVELPDGARQIRQYSLSRSPGSAVRAIT
                     VKRVHGPAAAGPDGEVSHHLHTRVRTGDTLRVSAPYGDLVLRDSGAPVLLASAGIGCTP
                     MLSMLEHLSDTGHTAPVTVLHADRSPADHALRGDHRSLTHKLPDASARFWYEADAEPGD
                     SHGRLDLTDVPVAPGTTAYLCGPLPFMRAARAQLLAKGVRAADIHYEVFGPDLWLAAG"
     gene            14710..15300
                     /locus_tag="IE248_RS02235"
                     /old_locus_tag="GCM10010336_04540"
     CDS             14710..15300
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154135.1"
                     /locus_tag="IE248_RS02235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04540"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_190029853.1"
                     /transl_table=11
                     /translation="MASPMSADRFISALRHESLTVVEVGAWRTHNRNHKGPWGPVHGVM
                     VHHTVTHGTGYTVRLCREGDEDLPGPLCHGVITKDGRVHLVGYGRANHAGAGDSDVLAA
                     VIAEKRLPVDHRADTDGNRHFYGFECENLGNGEDPWPAVQLDAIARAAAALCRVHGWTA
                     RSVIGHREWQPGKIDPRGFTMDAMRVRVAERLK"
     gene            15338..16225
                     /locus_tag="IE248_RS02240"
                     /old_locus_tag="GCM10010336_04550"
     CDS             15338..16225
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741533.1"
                     /locus_tag="IE248_RS02240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04550"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_190029854.1"
                     /sec_met_domain="PALP (E-value: 6e-19, bitscore: 64.6,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLQPRPPSPLVEVTDERFAARGVRLLLKRDDLVHPELPGNKWR
                     KLAPNLRAAVEGGFPALVTFGGAYSNHLRATAAAGRLLGLPTIGVVRGDELAGRPLNES
                     LARCATDGMRLRFVSRAEYRRKAEPEVLARLLAGAGAAGAYVVPEGGSNALALRGCAEL
                     GRELRGAADVVAVACGTGGTLAGLAAGLGPGGRALGVPVLAGGFLGAEIRSLQLAAFGA
                     PAGDWSLAEGFHHGGYARVPAELEAFAADFEARHGLPVERIYVAKLLWALTELTRSGAF
                     PPGTTLAAVVTGRP"
     gene            complement(16264..17844)
                     /locus_tag="IE248_RS02245"
                     /old_locus_tag="GCM10010336_04560"
     CDS             complement(16264..17844)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521043.1"
                     /locus_tag="IE248_RS02245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04560"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_073798223.1"
                     /transl_table=11
                     /translation="MEVLPLVALVAGSAVVAAVARRTPVPAPLLLVAAGLIAGYVPGVP
                     PYALDPHIVLPLLLPPLLYTAGVDSSYLDLRANIRPVALLSVGYVIFATVVVGYAAFLL
                     VPGLSLPVALVLGAVIAPPDAVAATAIARKLGLPNRITTILQGESLVNDATAITAYNVA
                     LAAVIGTSAGWAGGIAEFLLASVGGVGVGLLLMVPIHHLRKRLREPLLQNTLSLLIPFV
                     AYAAAERVHASGVLAVVVVALYLGHRNWQVDFATRLQEAAVWKMVAFILESVVFALIGL
                     QLPVVMKGLGEYQGVDAAWYAVVVFLVVVVARYVWVFPATFLPRVLSERVRRREPEVNW
                     KAPVVVGWAGMRGVVSLAIAFSVPISVPHRNLILFLTFTTVIATLVVQGLTLPPLIRVL
                     RLPKRDVQAETLAEAQAQSEASRAAEERLEELLADPGNDLPPPLVERLRTVLERRRNAV
                     WERLGEVNAVTGESADDVYRRLAGEMIEVEREVFVALRDRRQIDDEMLRALLRRLDLEE
                     AAAYREESP"
     gene            17909..18169
                     /locus_tag="IE248_RS02250"
                     /old_locus_tag="GCM10010336_04570"
     CDS             17909..18169
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="IE248_RS02250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04570"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_008741531.1"
                     /transl_table=11
                     /translation="MSECTHVPELPRPEPVPRGQTCPDCLALGSHPVQLRLCLWCGYVG
                     CCDSSPHRHATAHYQETGHPVIRSFEPGETWRWCYVDGSIV"
     gene            18383..18796
                     /locus_tag="IE248_RS02255"
                     /old_locus_tag="GCM10010336_04580"
     CDS             18383..18796
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="IE248_RS02255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04580"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_008741530.1"
                     /transl_table=11
                     /translation="MSQIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVEATVEENRTVSISLYKQRGAGPGPA"
     gene            18808..19797
                     /locus_tag="IE248_RS02260"
                     /old_locus_tag="GCM10010336_04590"
     CDS             18808..19797
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741529.1"
                     /locus_tag="IE248_RS02260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04590"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_079196278.1"
                     /transl_table=11
                     /translation="MPVRGGDLPRVRHEVDGGIPEQQHARPHPADADAEYGFLDSAERR
                     AGPMSDNQHDQPESPEAAATAPVTPAPPLAAADPRDRSGARALFFELRELPEGSVERAE
                     LRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATP
                     TVVGEIKRHFRDKGWAVRVPRRLQELRLSLTTATAELSQQHGRSPTVHELAERLGISEE
                     EVLEGLESANAYSTLSLDVPDTDDESPAVADTLGSEDEALEGVEYRESLKPLLEGLPPR
                     EKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(19807..20277)
                     /locus_tag="IE248_RS02265"
                     /old_locus_tag="GCM10010336_04600"
     CDS             complement(19807..20277)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741528.1"
                     /locus_tag="IE248_RS02265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010336_04600"
                     /product="hypothetical protein"
                     /protein_id="WP_008741528.1"
                     /transl_table=11
                     /translation="MSKKPASNAPATEATGATGTGAAAAALPGRLTAAAALTALEGLAL
                     AGLGVYMLFVGIAGDPDSPQQAETGGVTLLALAALPLIAARGLRLGRRWSRGPALITQL
                     MALPVAWTLWTTGGAMAAAAVGLALAAVAVVALLVNPTATEALGIGPGERTR"
     misc_feature    20942..20957
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
ORIGIN
        1 gttacggcat cttgccattc ggactgacgc attcaggcag ctcgtcaggt caaaatcgga
       61 taacggacat ccccggcggc ccatcagccc tgcgggcgct ggctcttccg gccggactat
      121 gcgctgtgac cagcgacttt caccgcagca tttactgtgc gtctcgactg ttggacagta
      181 aggtttggac ctttcgccaa aaccgggaca gcaggcttag ggtcgagcag gaatcgactc
      241 gtctgggcga gcgttcttcc ggtaaaacgg atccttacac ccctcaccag gggctcaggg
      301 cgcgcgtgcg gcgcgcccgc gcgtacgaac ctcccctccg cgcagacggg caagccgtcg
      361 gcgcggagta cggacgcggt gcccgcccac cccttaacca ggagtggtca ccctcaacga
      421 ttcaaaaact taaggggcca agaaagtggc agcggagatc gtcaatcctc gcagcgacag
      481 cgggacggac aacaaccccg atgcggtgtt cgcgctgcac cggggcggca agatggccgt
      541 gcaggccacc gtgcccgtca acgacaagga cgacctgtcc ctcgcgtaca cgccgggtgt
      601 ggccaaggtc tgcaccgcca tcgcggagaa cccggagctc gtccacgagt acacctggaa
      661 gtccaacgtc gtggccgtcg tcaccgacgg tacggccgtg ctcggactcg gtgacatcgg
      721 gcccgaggcc tccctccccg tgatggaggg caaggccatt ctgttcaagc agttcggtgg
      781 ggtcgacgcg gttccgatcg cgctcgcgac caaggacacc gaggagatca tcgagacggt
      841 catccgtctc gcgccctcgt tcggcggcgt gaacctggag gacatctccg ccccgcgctg
      901 cttcgagatc gagcgccggc tccaggaagc cctggacatc ccgatcttcc acgacgacca
      961 gcacggcacg gcgatcgtga cgctggccgc catgcgcaac gcggcgaagc tgaccggccg
     1021 caccctcggc gacctgcgcg ccgtgatctc gggagcgggc gcggcgggca tcgccatcgc
     1081 caagatcctg gtggacgcgg gcatcggcga cgtctgtgtc accgaccgca agggcgtcgt
     1141 ctccgcggac cgctccgacc tgacggacgt caaggcggag atcgcgggcc tgacgaacaa
     1201 gagcggcctg aacggctcgc tggagtccgc cctcgcgggc gccgacgtgt tcatcggcgt
     1261 ctccggcggc acggtgcccg aggaggcggt ggcctcgatg gcgaaggacg ccttcgtctt
     1321 cgccatggcc aacccgaacc cggaggtcca cccggaggtc gcgcacaagt acgccgcggt
     1381 cgtggccacg ggccgctcgg acttcccgaa ccagatcaac aacgtgctgg cgttcccggg
     1441 catcttcgcg ggcgccctga aggtccgcgc gacccggatc accgagggca tgaagatcgc
     1501 cgccgccgac gccatcgccg gcgtcgtggg tgacgagctc gccgccgact acgtgatccc
     1561 ctcgccgttc gacgagcgcg tcgccacggc cgtctcggcc gcggtcgccg ccgcggcgaa
     1621 ggccgacggc gtggcccgcc tggcctgagc gtcacccggt tccacgtgaa ggggcccggc
     1681 cggatcactc cggccgggcc ctttcgcgtg acgcggcacc cgggacaccc gtacgggcgt
     1741 ccgggggacg cggcggaacg caccctcctg gcccccgaac cgggaggggt cgttcgtcgt
     1801 ggggccgtcg agccggaatg acaggctcat gacgagcagt gccgcgcggc ttgaatatta
     1861 ccccgccccg gggctggttc atgacgttcc ggttccatcc tccgatggcg caagaaccca
     1921 tgggggagcc gcagttgaca aggtgtctca ctattccgct ccggtccccc gcccacccat
     1981 ctggacgcag ccccgcaccc gcccggttcc cgcggatccc attgatccga acccgccggg
     2041 gaagccgggc ctggtggcag cccctaccga gcggtagcgt ctggcggcat gttcgctgcc
     2101 tacgccgccc gaatcgaccg tgaccagccg ctgagcggcc ttgagctggg cgagcgcccg
     2161 gcccccgagg cccgccccgg ctgggtgacc gtgaacgtca aggccgcctc gctcaaccac
     2221 cacgacctgt ggtcgctgcg cggggtgggc ctcggcgagg acaaactccc gatgatcctc
     2281 ggctgcgacg ccgccgggat cgaccaggac ggcaacgagg tcgtcctgca ctccgtgatc
     2341 ggccagagcg gccacggggt cggccccgac gagccgcgct ccatcctgac cgagcgctac
     2401 caggggacct tcgccgagca ggtgaccgtc ccggcctgga acgtcctgcc caagcccgcc
     2461 gagctgtcct tcgaggaggc cgcctgcctg ccgacggcgt ggctgacggc gtaccggatg
     2521 ctgttcacca acgcgggcgt ccgccccggt gactccgtac tggtccaggg cgcgggcggc
     2581 ggggtcgcga cggccgcgat cgccctcggc aaggcggcgg gcctgcgggt cttcgccacc
     2641 agccgggacg aggccaagcg caagcgggcc gtggagctgg gcgcgctgga ggcgtacgag
     2701 ccgggcgcgc ggctcccccg gcgggtggac gcggtgatcg agacggtcgg cgcggccacc
     2761 tggtcgcact cggtgaagtc gctgcggccg ggcgggacgc tggtcatctc cggcgccacc
     2821 agcggggacc ggccggcgca cgccgagctg acccggatct tcttcctgga gctgaaggtg
     2881 gtcggctcga ccatgggctc gaaggacgag ctggaggacc tgctgtcctt ctgcgcggcg
     2941 acgggcgtgc ggccggtgat cgacgaggtg ctgccgctgg accgggcgcg ggagggcttc
     3001 gagaagctcg cgtcgggcga cctgttcggc aaggtggtcc tgacggtctg accggaccgg
     3061 ccgcgcaccc ctcaccctcc cactcacgtc aaccggggtt gacgacctcc gctcgtcaac
     3121 ctacattgac gggcatgacg gaagccactg atctcgccga acgggccggt gaccgcgacc
     3181 cgcgcgtggg cctgcgtgcc gtggccgccc tccgcagact gctggagcag ctggaggcgg
     3241 tacaggtgcg cagtgcccgc gcgcaggggt ggtcctggca ggagatcgcg gccgagctgg
     3301 gcgtgagccg gcaggccgtg cacaagaagc acgggagggt ttgatgttcg agcgcttcac
     3361 gaccgcggcc cgggacgccg tgacgggcgc cgtggccgag gcccggcggg ccggggcggc
     3421 caccgtcacc gaggaacacc tgctgctggc gctgctcgcc cagggagcgc tggacccgct
     3481 gggcgtggac cgggctgcgg tcgccgccgg cctcgcccgg gcccgccgcc ggggcgggat
     3541 gtccagggcc gacgaggagg cgctggccgg cctcgggatc gacctgaccc ggatcctgtc
     3601 ccgggtggag gagacccacg gcgagggcgc cctcgcggcc acggcccccc ggcggcggac
     3661 cctcgggacc tcgctccgct cggccctcgg ccgcccggag ccggccggcc gccacgtccc
     3721 cttcgccccg ggctcgaagc gggtgctgga agggtccctc cggatcgccg tgggccgcgg
     3781 ggaccgccac atcgccgccc cgcacctgct cctggccctg ctgtcccgcc cgggcacggt
     3841 ctgcgaggtc ctcgcggacc acggggtcac ctacgaggcg gccgagtcgg gcctgacggg
     3901 cccctaaccc ctgagcgtgc cggtgacgcg ggcggcggcc gcggccagat gggcgcgggc
     3961 ctcggccagc tgggccgggg agaccccgtg gtcgcgggcg gcgtcgcgga cgtcgtcgcg
     4021 gaaccggtcg agcagccggt ccaggtcccg ggccgggtcg gccgtcgggg ccaggtcctc
     4081 ggcccagtcg gagccggcgg cggccgaggc ggtggcactc gtggcgttgg cggcgccgcc
     4141 ggcaccggtg gcaccgccgc cggagcccgc gcccgcggat ccgccgccga gccaggcgcc
     4201 ggccaggctg cccagcatgc cgcccgactt cgcgaactgc tcctggaact gggccgcgat
     4261 gcgctggacc tcctcacggg cccgctcctg cgcctccttg gcctggcggc gggcctgctg
     4321 cgcctcctcg cgggcccggc ggctctcgtc cttcgcccgc cgcgcctgct ccttccactc
     4381 gtgcttcgcc ttgcgcagct cctccttggc cgccgcccag gacgcgtcct cgacgggggt
     4441 cgcggtcgcc gaggccgcgg cccgcatctc gcgccgcaga tcgccggccg cgcccctgac
     4501 gtccgcgcgg atctcggcgg ccagctcgga gaccgaatcg cggatctcca gctccaggtc
     4561 ggcgagctcg ccgcggcggt cggccagttc ggcgcggccc gcctcggtga tggagtacac
     4621 cttgcgcccg ccctcggtgg cgtacgtgac caggccttcg gcctccagct tggcgagccg
     4681 ggggtacacg gtgcccgcgg agggcgcgta caggccctgg aagcgctcct ccagcaggcg
     4741 gatcacctcg tacccgtggc gcggcgcctc gtccaggagc cccaggaggt agaggcggag
     4801 gcgtccgtgg gcgaagacgg gcggcatgtc agagcacctt cttgtcgagc gtgagggggg
     4861 cggagggggt cgcggcgtcg gcggccggtc ggcgcagcag ggcgatggcc ccggagacgg
     4921 tggtggcccg cagggtgccg gtccccgcgc cgagggtgcc ggtgatccgc ttggcgccca
     4981 gctggccgga gacccggagg tcctcgaagg cgttggagac cccgccggtg gcggtgttgg
     5041 cctcgacgcg ggcgtcggcc gggtgcggca gacggatcgc gacctggccg gagacggagt
     5101 tgaggaagat gtccaccggg ctgggcgcgg ccgggtcgag ggccaggtcg atgagcatgt
     5161 cgccgctgac ggagtcggcc cgtacgctgc cgccggcgcc gtcgaccacg gtcaggccgc
     5221 cggagacgga gtggaaaccg agctcgccgg tgacggactg ggcctcgacg ctgccggaca
     5281 cggtgtgcgc cttgaccctg cccgagaggc cgacgagcgt ggcgtcgccg gagactccgt
     5341 tgacgtcggt gccgccgcgg atgccggaga cgaacgcggc ggcgctgacg gtggccacct
     5401 ggacgcgggt cgcggcgggg acggtgaggg tgacggtggc gctgcgctcc caggccttgc
     5461 ggccgctgcc gtcgccggag ccggcggacc aggccttcca gggcttggcc gcgagccact
     5521 ccttgaagcc gcgggtgccg ttccagggga ggtcctcgta ggaaacggtg aggacgccgc
     5581 cgtcctgcac gacctggagc ggcggcccgt cgaccgcggc gacctccagc cgggcggggc
     5641 cctcgtcgga ggcgacgacg ttgacggtcc cgccgaccag gcgtacgtgg agctcggcga
     5701 cgggctcgtc gaaggtgagc ttctgcggtt cggcgaccga ccgcgtcgac gtctgctctg
     5761 tcattgcgga tcctcctcgg acgtgcgcgg actgggtctc gacgctcgca acatatcgcg
     5821 tctcccgaaa gacacgatat atcgcgcccc cccgaagtca agccacccgc ctccggccgc
     5881 cggcctcagc cccgccggcg tttgaggcgc gggggtccgg gggccgcccg ctggacctcc
     5941 gccccgcccc cgccactcgg cccggccggc gcaaccccag ccccgccggc gtttgaggcg
     6001 cgggggtccg ggggctggcc cccggcgacg gcgccgcacg tcagggcagg cttcggcccc
     6061 gcgggccgcc tgctggggcc ccgccccgcc ccgccactcg gcccggccgg cgcaacccca
     6121 gccccgccgg cgtttgaggc gcgggggtcc gggggctggc ccccggcgac ggcgcgatct
     6181 cagccccgcc ggcgtttgag gcgcgggggt ccgggggctg gcccccggcg acggcgccgc
     6241 acgtcagggc aggcttcggc cccgcgggcc gtctgctggg gctccgcccc agaccccgcg
     6301 cctcaaacgc cggcgaggct gaaatggccc gggccacagc ccaagacgag ccacccgagc
     6361 aaccaggcag gcgcggccaa gcggtgcggc cggagcaccc ggacagacgg cgctggcggg
     6421 cgtacgggca ggcgacgtag ccagggcggg cgcgggcgcg accggggcag gagcagccgg
     6481 gggccggcgc gggcaggtgg tcggggtagc gccccggagg ggttaggcgg ctaggagggg
     6541 gctttcgtgg tggtggagcc acgcccggta cggcggcgtc cgcagcgcgg cctcgcgata
     6601 ggccgagcgg aggtcctcga agacctccgc gtgcgccccc ggccgggtcg ccagcagcag
     6661 ccgcaccgcc agcgggtccc ccgacagcgg ccggatcgcc atgtcgtccc gcggcccgga
     6721 cgtcggctgg cacggcgcca ccgcctcgcc ggagatgatc agcgaggtcg cggtgtggta
     6781 gtcggcgtgc aggacaggcg gatcgagccc cgcgcccgcg aagacccgcc gcaggccgtc
     6841 ccactcgccg tcgaccgacg ggtcgaccgt ccaccggtcg cgcgccaggt cccgtaggtc
     6901 caccaccgcc cgcgccgccg ccggatggtc ccgggacatc gacacgaact gcggctcccg
     6961 ctccatcagg acccgcatct ccagcccggc gggcacccgc agcgggctgc cctcgacctc
     7021 gtgcacgaac gccacgtcca gctgacccga atccaccatc cgcagcagcg cgttggccga
     7081 gaggtccacc accagcgtgg tctcggtgtc cggaagcctg cggtgcagcc ggcgcagcca
     7141 tcccggcagg gcgcggctcg ccgtggagcc cagccgcagc ctcggccccc gggccaccgc
     7201 acgcgcctcg gccaccagcg cggccatctc ggcgagcagc ggacgggccc ggccgagtac
     7261 ggtgcgcccg aacggggtgg gccggcagcc ggtccgctcg cgcaggaaca gctcgccgtc
     7321 cagggcccgt tcgatccggc gcagctgggt cgtcaacgag ggctggctca cgccgagttg
     7381 ccgcgccgcc ttgtgcaggc tgccggcgtc ggcgatggcg cacagggcgc gcaggtgcct
     7441 gacctcaagc tccatgtcca gagggtaggc cggggccagt ggaccgcacc agccactgac
     7501 gacccaccga atcccgccat tctcagggaa gttggcctgc cgaaaccctc cgataacccg
     7561 gagctatcgg tggctgacat catcccccgc ccccttccgc tcccgcagaa tccggtaccg
     7621 aaccacccac cccccgcacc ggatgagtag gagccccccc acatgcgcca ctcccgtacc
     7681 tcccgaacgg ccgtactggc cgccaccctc ggcctcggcc tggccacggc cgtcgtcggc
     7741 gtcgccccca ccgccagcgc tgccccggcg cccgtcggca acgccgccag ctacgccgcg
     7801 tacgagcgct cgcaggagaa cgagtccgcc aacgccgcgt tcttcgacgc ggtccggcgc
     7861 tcggtggccg agcagcgtgc cgcgaacccc ggcatccggg ccgtgaccgt cacgtacaac
     7921 acccgcaacg ccccgagctt ccgtagccag atagcccgtt ccacgcagat ctggaacagc
     7981 tcggtgtcca acgtcaagct ccaggaggtt tcctccggcg ggaacttctc gtactacgag
     8041 ggcaacgact cgcgcggttc ctacgcgagc accgacggcc acggccgggg ctacatcttc
     8101 ctcgactacc agcagaacca gcagtacaac tccacccggg tgaccgcgca cgagacgggc
     8161 cacgtgctgg gtctgccgga ccactactcg gggccgtgct ccgagctgat gtcgggcggc
     8221 ggtccgggca cctcgtgcca gaaccccaac ccgaacgccg cggagcgctc ccgcgtgaac
     8281 cagctgtggg ccaacggcct ggtcggctcc ggcctggggt cgaagggcta gccggccgcc
     8341 ggggcgacgg acgccggaca gtccgggttc cggcaggaac ccgccaccca ctccggtacg
     8401 aagatgccca gggacttgcg ccgcctgacg acggtgtcga cggatccgcc acaggccggg
     8461 cacacgcgct gcgcgtgtcc ggcctgcggt gcgaccctga tgcgtgcctg ctcttcgccg
     8521 cgctgctgac cggtcatacc tccacggtag gccggtttcc ctccgcgcgg ggggtcagag
     8581 cgcacgggcg taggtggtga cgagctggcc gccgccgaag gtcttgaccc cggtcagctc
     8641 cagcccacgc ggcgcgaagc cggcgcgcga catcgggatg ccggagcccg cgaacaccgg
     8701 gtacgtcttg acgatgaact cgtcgatctc gtcggccagc cggccggcca ggtcggcgcc
     8761 tccgcacagg tagatcccga ggccgggccg cgccttcagc tcgcgcacca gcgccacggc
     8821 gtccccgctg aagatcttca cggccgggtc gggcgactcg gtcagggacc gggacagcac
     8881 gtactgctcc aggtgggcgt aggggctggt gatccccgcc ttgagcgccg ggtcataggt
     8941 gccgcgcccc atcaggaccg tgtcgaagcg cttcgcggcg cccgcgccga cgcccatgag
     9001 ggcccggacg tgggtgggca gggtctccgg gaactccgcc gccatgtggg cgatgtactc
     9061 cgggtcggtc cagcgggtga ggaagtcacc gtccccatcc gggtccgcga tgaacccgtc
     9121 gacggacgtg ccgacgtaat acgtgagctt gcgcaagtag atctctttcg ctcgaccgca
     9181 cccctcgatc agggcacgtc aggcaaagta ctgcacctga agtacttcga caagcccctt
     9241 acccctcggc ccgccccgtc tcagccccgc ggcttgcgcc acatcggcca catcagcggc
     9301 ccgcccggca gccgcaccgg ctcccccgtg acctcccagc cgagccgctc gtacagcacc
     9361 ttgctgcgct cgctgctcgc ctccagatac gccggcaggc cctcgcggtc gcagcgctcc
     9421 agcaccggac gcatcagttc cgtgccgagc ccctccccct gccggccggg cgcgaccgcg
     9481 atcatcagca ggtactcgtg ctcctcggcg gtcgggtgca ccgcgcccgt caggcgcccc
     9541 accagctcgc accgctcgtt gtcgggatcg gccgccgccc gcatccgcgc cggcacctcg
     9601 tcctcggcgg cctcggcgtc ggggtcacca gccgggaccc gcagccacag cgccgccgcc
     9661 gagccgtcca ccgcgcagtc gatccggccc tcctccagcg ccacgtccac gaagacgccg
     9721 aggaacttcc cgtgcaccgc cgcccggtgc tccggatccg ggaagaccca gccgctcacc
     9781 gggtcgtcgc ggaaggccac gtccagcagc cgcgccaccg cgtcccggtc ggactggtcc
     9841 gcctgacgta tctccagcac catgggtcac acccttcgct cacgcctcaa cagccttgag
     9901 cgatcctaga gttgaccccg aatgcgcgga aagccctgtt ccggcacctg atggtgccgg
     9961 aacagggctt gcgcgccgcc gccggacgcg tcctacgagg tcacctggta cggcgcgtga
    10021 cgaactccgc cagcgccagc agcccgcccg ccgccgcgag gtcgggaacg gcccgggaca
    10081 gctgctgcac cgcccggccc atccggtccg cggcatgggc ctgcgcccag tcgcggccgc
    10141 cggcccgctc gaccgccgcg gccgccgcgt gcacgtcgtc cccggtcatg gggcccgcgt
    10201 acagcgcggc cagctccttg cccgccgtgg tgcccgaggt gagggcggcc acgaccggga
    10261 gcgacttctt gcgggcgatc agatcggccc cggcgggctt gccggtgtgc cccggatccc
    10321 cccagatgcc gatcaggtcg tcgatcagct ggaaggccag cccggcctcc cgcccgaagg
    10381 cgtccatcgc gtcgacctcg tcgggccccg cgcccgcgta cagcgcgccg agcgcgcagg
    10441 cgcagcccag cagggccccg gtcttggcca tggccatcgt caggcactcg tcgagcgaga
    10501 cgtccgggcg ctgttcgaag gcgcagtccg cctgctggcc ggcgcacagc tcgatgatgc
    10561 aggtcgccag ccgggccgag gcggcggccg aggccggatg cccgtcctgg accagcagcc
    10621 gcagcgcgag cgcgagcatg gcgtcgcccg tgatgatcgc gtccggcgtc ccgaagacgg
    10681 tccaggccgt ggcccggccg cgacgccgga cgtccttgtc gatgacgtcg tcgtgcagca
    10741 gcgtgaagtt gtgcgccagc tccacggcca ccgccgcccg cacgacggcc cgcagaccgt
    10801 cgtccccgtc cccgtccccg gtgtccgccg gcccccgcag ggcccgggcc gcggcgagca
    10861 cgagggcggg ccggatggcc ttgcccgcgt tgcccgccgc cggggtgccg tccgcgtgct
    10921 cccagccgaa gtggtacatc gcgacgcgcc gcatcgaacc gggcaggctc tcgaccgtcc
    10981 ggcgcagttc cggattgacg gcgtctctcg tccgctccag cagggccgcg gcttcgtggc
    11041 cctcgccggc cgtgatggtc tcagtggtcg ccatggcgtg tcccgtgtgt cctttgcgtc
    11101 cgctcccgcg ttccggccgg ccggctcagc gccagcggcc gatctcgacg ttctccagga
    11161 cgccgagcgc gtccggcacg aggaccgcgg cggagaagta ggcggtgacc aggtaggaga
    11221 tgatcgcctg ctcgctgatc cccatgaagc ggaccgacat gctcggctcg atctcgtccg
    11281 ggatcccggg ctggtggagg ccgacgaccc cggactcctc ctcaccggtg cgcatgcaga
    11341 ggatggacgt cgtgcgcgcg tcgctgatcg ggatcttgct gctcgggaag atcggcacgc
    11401 cgcgccagga cggcacccgg tggccgccga cgtcgatcga ctcggggtac aggccgcgcc
    11461 ggttgcactc gcggccgaag gcggcgatgg ccttggggtg ggcgaggaac atcttggaac
    11521 cgcgccgcat gctgagcagc tggtccatgt cgtcggggct gggcacgccg tcgtgcggct
    11581 ggatgcgctg gtcgtagtcg gcgttgtgga gcaggccgaa gtcggtgttg ttgagcatct
    11641 cgtgctcctg gcgctcccgc agcgcctcga ccgtgagccg caactgctgc tcggtctggt
    11701 tcatcggctg gttgtacagg tcggcgacgc gcgtgtgcac ccgcaggacc gtttgcgcga
    11761 tggagagttc gtactcgcgc ggcttggcct cgtagtccac gaaggtgccg ggcaggacgg
    11821 cctcgccctg gtggccggcg gagaggtcga tcgcggcctc gccgtacttg ttggtccgct
    11881 gggcgggcag cgaccgtacg gactcgacgt gcgcgcgcag gctgtcgacg cggtcggcga
    11941 ggagctggaa gtcctggcgg gacaggacga gggcggtgcc ggaggtggcg gcgcgggcgg
    12001 tgtactccca gatcgcctcc tcgtccacga gggagtcctc gccgaagtag gcgccgtcgg
    12061 cgacggtctg caggaccgcg tcctcgccgt aggggccggg gccgacctgg tcgatgcggc
    12121 cgtgagcgag caggaacacc ttgtcggagg ggctgccgaa ggaggtcagc tcctggccgg
    12181 ccgcgaagtc gagctgctgg caccgcgcgg cgagctcggt gaggacgtcg aggtcctcgt
    12241 aggcgcgcag cagcgggagc tcgccgagct cggccgggat gacctggacc tgggtcccgg
    12301 tcttgatgaa ctccacgcgt ccgtcgccga cggagtagct cagccgccgg ttgacccggt
    12361 aggtgccgcc ctgtaccgac acccacggca gcatcttcag gagccaccgc gaggtgatct
    12421 cctgcatctg cggcgcggac ttcgtcgtgg ttgccaagtt ccgtgcggcc gaggtcgcga
    12481 gactgcgctg cggcggagac tgggcctcgg tttcggaacc tgcctggacc gacatgtgtt
    12541 tccctttcga tcactccatg ggtctgctgg gccagccttc agcacacgac gtggtgggac
    12601 cattacacaa aagggtggga ctactccgtg tgggtctggg cactctttgg ggtcagctcc
    12661 cgcgtcccag gccccttgag ccccaccggt ttcagccacc tcacgccaac cgtcagcttt
    12721 aacttgcaag acagatgcaa ctttccgtac ggtggcgcca tgcggctgac ccgattcacc
    12781 gatctggcgc tccgcgtcct gatgcgcctg gccgtcgcgg acgcggacct ccccaccacg
    12841 cgcgacgtgg cggcgaccat ggaggtcccg tacacgcaca gcgccaaggt ggtggccagg
    12901 ctgcggcacc tcgggctgat cgaggcgcgg cgcggccgcg gcggagggct cgcgctcacc
    12961 gccgccggac gggccgcctc ggtgggcggg gtggtccgtg aactggaggg cgccggtgac
    13021 gtcgtggact gcgacggggc cgtgccctgc ccgctgcgcg gcgcgtgcgt gctgcgcggc
    13081 gcgctgcgcg gggcccagga ggcgttcttc gccgccctgg accccctgac ggtgaacgac
    13141 ctggtggcgg ccccgaccgg gccgctgctg ctgggcattt cgagcggccc gccggggcgg
    13201 accgtagacc cctgaccccg ggccgggtgg ccggttcccg ctgcccggac cccacgcctc
    13261 gaacaggtgc ccccatcccc ccacgcacca cgcccaaaaa tacgcatttc agattccaat
    13321 taacgcgacc gaggagttcc gcatgctgtc ggagaagtcg accgagaccg tacgagccac
    13381 cctgcccgcc gtcggcgcgg ccatcggcga catcgcggag ctcttctacg cgaagctgtt
    13441 cgcggcccac ccggccctgc tgcgcgacct gttcaaccgc ggcaaccaga actccggcgc
    13501 ccagaagcag gccctggccg gctccatcgc cgccttcgcg acccacctcc tgacccaccc
    13561 cggcacccgc cccgacgtga tgctgaaccg gatagcccac aagcacgcct cgctcggcat
    13621 cacccgcgag cagtacgaga tcgtccacca ccacctcttc gaggccatcg cggagatcct
    13681 cggcgaggcc gtcacccccg aggtcgccga ggcctgggac gaggtctact ggctgatggc
    13741 gggcgccctc gtcgccatcg aggaccgcct ctacgcgcag cggcaggtgc tcgcgggcga
    13801 cgtctggcgc gactggcgga tcgccgcccg gttcgaggag acggccgact gcgccacctt
    13861 ccacctcgtc ccggccgacg gcgcccccgc ccccgccttc gcgcccggcc agtacgtctc
    13921 cgtacaggtc gaactccccg acggcgcccg gcagatccgc cagtacagcc tctcccgctc
    13981 gcccggctcc gcggtgcgcg cgatcaccgt caagcgggtc cacggcccgg ccgcggcggg
    14041 ccccgacggc gaggtctccc accacctcca cacccgcgtc cgcaccggcg acaccctgcg
    14101 cgtctcggcc ccgtacggcg acctggtcct gcgggactcc ggcgcgccgg tgctgctcgc
    14161 ctccgccggg atcggctgca ccccgatgct gtcgatgctg gagcacctgt ccgacaccgg
    14221 gcacaccgcg cccgtgaccg tcctgcacgc cgaccgctcc cccgccgacc acgcgctgcg
    14281 cggcgaccac cggagcctga cgcacaagct gccggacgcc tcggcccggt tctggtacga
    14341 ggcggacgcc gagccgggcg actcccacgg ccgcctcgac ctgacggacg tcccggtcgc
    14401 gcccggcacc accgcgtacc tgtgcgggcc gctcccgttc atgcgggccg cgcgtgcgca
    14461 gctgctggcc aagggggtcc gcgccgcgga catccactac gaggtgttcg gcccggacct
    14521 ctggctggca gccgggtgac ccccgcggcg ggcgggccgg ccggggtggc cggtgcggcc
    14581 gggacgggtg tccggatcgg ctcgctcgcc gtacgaatcc actagcggcg gaaggatcgc
    14641 ctccactaca ccggtacgta acggggtgac cacgaaaggt caccaccacg caccgcaaag
    14701 gaggcggtca tggcctcacc catgtccgcg gaccggttca tcagcgcact gcggcacgaa
    14761 agcctgaccg tcgtggaggt cggcgcctgg cgcactcaca accgcaacca caagggcccc
    14821 tggggccccg tgcacggggt gatggtccac cacaccgtca cgcacggcac cgggtacacc
    14881 gtccggctct gccgcgaggg cgacgaggac ctgcccggcc cgctctgcca cggcgtgatc
    14941 accaaggacg gccgcgtcca cctggtcggc tacggccgcg ccaaccacgc gggcgcgggc
    15001 gactccgacg tcctggcggc ggtgatcgcg gagaagcgcc tccccgtgga ccaccgcgcc
    15061 gacaccgacg gcaaccggca cttctacggc ttcgagtgcg agaacctcgg caacggcgaa
    15121 gacccctggc cggcggtgca gctcgacgcg atcgcccgcg cggcggccgc gctgtgccgc
    15181 gtgcacggct ggaccgcgcg ctcggtgatc ggccaccgcg aatggcagcc cggcaagatc
    15241 gaccccaggg gcttcacgat ggacgcgatg cgcgtgcgcg tcgcggagcg cctgaagtag
    15301 cgcggcggcc gggccgggct ccgccgacaa tgggcgggtg aaccccttgc agccccggcc
    15361 gccgtccccg ctcgtcgaag tcaccgacga gcggttcgcc gcgcgcgggg tacggctgct
    15421 gctgaagcgg gacgacctcg tacatccgga gctgcccggg aacaagtggc gcaagctcgc
    15481 gccgaacctg cgggcggcgg tggagggcgg cttcccggcg ctggtgacgt tcggcggggc
    15541 gtactcgaac cacctgcggg ccacggcggc ggccgggcgg ctgctgggcc tcccgacgat
    15601 cggcgtggtc cgcggggacg agctggccgg gcggccgctg aacgagtccc tcgcgcggtg
    15661 cgcgacggac ggcatgcggc tgcggttcgt ctcccgggcg gagtaccgcc gcaaggccga
    15721 gccggaggta ctggcccggc tgctcgccgg ggcgggcgcg gccggggcgt acgtggtgcc
    15781 ggagggcggc agcaacgcac tggccctgcg gggctgtgcg gagctggggc gggagctgcg
    15841 gggcgcggcg gacgtggtcg cggtggcctg cggcaccggc ggcaccctcg cgggcctggc
    15901 ggcgggcctc ggcccgggcg ggcgcgcgct gggcgtgccg gtccttgcgg gcggcttcct
    15961 gggggcggag atacgttccc tccagctggc cgcgttcggc gccccggcgg gcgactggag
    16021 cctcgcggag ggcttccacc acggcggcta cgcccgcgtc ccggcggagc tggaggcgtt
    16081 cgccgccgac ttcgaggccc ggcacggcct cccggtcgag cggatctacg tggcgaaact
    16141 gctctgggcc ctgacggagc tcacccgctc cggcgccttc cccccgggca ccaccctcgc
    16201 cgccgtcgtc acgggacgcc cgtagccccc gggcgtccgg cccccggccc cggcccgcag
    16261 gggctacggg gactcttcgc ggtaggccgc cgcctcctcc aggtccaggc ggcgcaggag
    16321 ggcgcggagc atctcgtcgt cgatctggcg gcggtcccgg agggccacga acacctcccg
    16381 ttcgacctcg atcatctcgc ccgcgagccg tcggtacacg tcgtccgccg actcccccgt
    16441 caccgcgttg acctcgccga gccgttccca caccgcgttg cgccggcgct ccagcaccgt
    16501 ccgcagccgt tccaccagcg gtggcggcag gtcgttgccg gggtccgcga ggagttcctc
    16561 caggcgctcc tccgccgccc gcgaggcctc gctctgcgcc tgcgcctccg cgagggtctc
    16621 cgcctgcacg tcccgtttcg gcagcctcag cacccggatc agcggcggca gcgtcagtcc
    16681 ctgcaccacc agcgtcgcga tgaccgtcgt gaacgtcagg aagaggatca ggttccggtg
    16741 cggcacgctg atcggcacgg agaacgcgat cgccagcgag accacgcccc gcatccccgc
    16801 ccagcccacc acgaccggcg ccttccagtt cacctcgggt tcgcgccgcc ggacccgctc
    16861 cgacagcacc cgcggcagga acgtcgccgg gaacacccac acgtaccggg ccaccaccac
    16921 gacgaggaac accacgaccg cgtaccaggc cgcgtccacc ccctggtact cgcccagccc
    16981 cttcatcacc accggcagct ggagtccgat cagcgcgaag accaccgact ccaggatgaa
    17041 ggcgaccatc ttccagaccg ccgcctcctg gagccgcgtc gcgaagtcga cctgccagtt
    17101 ccggtgcccc aggtacagcg cgaccacgac caccgccagc accccggagg cgtgcacccg
    17161 ctcggccgcc gcgtacgcca cgaacgggat cagcagcgac agcgtgttct gcagcagcgg
    17221 ctcgcgcagc cgcttgcgca ggtggtggat cggcaccatc agcagcaggc cgacgccgac
    17281 gccgcccacc gaggccagca ggaactccgc gatgccgccc gcccagccgg cgctcgtccc
    17341 gatcaccgcc gccagcgcca cgttgtacgc ggtgatcgcg gtcgcgtcgt tgaccagcga
    17401 ctcaccctgg aggatggtcg tgatcctgtt cggcagcccg agcttgcggg cgatcgcggt
    17461 cgccgccacc gcgtccggcg gcgcgatcac cgcccccagc accagcgcca ccggcagcga
    17521 cagccccggc acgagcagga acgccgcgta cccgacgacc accgtcgcga agatcacgta
    17581 cccgaccgac aacagcgcga cgggccggat gttcgcccgc aggtccaggt acgaactgtc
    17641 cacgccggcc gtgtacagca gcggcgggag cagcagcggc agcacgatgt gcgggtccag
    17701 ggcgtacggc ggcacgccgg ggacgtaccc ggcgatcagc ccggcggcga ccagcagcag
    17761 cggtgccggc accggcgtcc ggcgggccac tgccgccacg acggcactgc cggcgaccag
    17821 cgccaccagt ggcaatacct ccatcgaaga tcaccctcgc tcgatttcat ccgactgagc
    17881 acgcccgtac ctcagtacgc tggccatcat gagcgagtgc acccatgttc ccgaactgcc
    17941 gcgccccgag cctgtcccac gtgggcagac ctgtccggat tgtctggcgc tcggaagcca
    18001 cccggtgcaa ctgaggctct gcctgtggtg cgggtacgtg gggtgctgcg actcctcccc
    18061 ccaccggcac gccacggcgc actaccagga gacgggccat ccggtgatcc ggagcttcga
    18121 accgggcgag acgtggcggt ggtgctatgt cgacggttcg atcgtctgag gcggggtagt
    18181 tcaaccctcc gccggttccc ctgatttggg ccccgcagac ccctagccac tgtgcgtgcc
    18241 catgggctta ccatcagtca ctgacagagg catggccgtc ctgggcgctc ctttcgggtg
    18301 ccatgagggg tgccgcgaca cgatcgaccg gatcgcggta gcgtcaccgg cgaacagagc
    18361 tcgtaccacc ttggaggtga gggtgtccca gatcgcaggc gagcccggga cccaggactt
    18421 cgtggaagtc cggctgccgg ctgcgggtgc ctacctgtct gtgctgcgaa cggccacggc
    18481 cggactcgcg gcacgtttgg acttcactct cgacgagatc gaggacctcc gcatcgcggt
    18541 ggacgaggcc tgcgcgatcc tgctccagca ggccgtgccg ggctccgtcc tcagctgcgt
    18601 cttccggctg gtggacgatt cgctggaggt gaccgtctcg gcacctacca ccgacggccg
    18661 cgcaccggaa cgcgacacgt tcgcgtggac ggtcctttcg gccctggccg gcaaggtcga
    18721 ggccaccgtc gaggagaacc ggacagtgag catcagcctc tacaaacagc gcggcgcggg
    18781 accaggcccg gcgtgagcgg cggggagatc ccggtgcggg gcggggatct gccccgggta
    18841 cggcacgagg tcgacggcgg catcccggag cagcagcacg cccggccgca cccggctgac
    18901 gcggatgcgg aatacggctt tttggactcg gcggagcgac gggcgggccc tatgagcgac
    18961 aaccagcacg accagccaga gtcaccggag gccgctgcca cggccccggt gacaccggcg
    19021 ccgcccctgg cggcggcgga tccgcgcgac cgcagtggcg cgcgggccct gttcttcgag
    19081 ctgcgggagc tgcccgaggg ctcggtggag cgcgcggaac tgcgcaaccg gctcgtccgg
    19141 atgcacctgc cgctggtcga gcacctggcg cggcggttcc gcaaccgcgg cgagccgctg
    19201 gacgatctga cacaggtcgc gacgatcggc ctgatcaagt cggtggaccg gttcgacccc
    19261 gaccgcggcg tcgagttctc cacgtacgcc acccccacgg tggtgggaga gatcaaacgg
    19321 cacttccgcg acaagggctg ggcggtgcgc gtgccccggc gcctgcagga gctgcggctc
    19381 tcgctgacga cggccacggc ggaactgtcc cagcagcacg gccgctcgcc gaccgtgcac
    19441 gagctggcgg agcggctcgg gatctccgag gaggaggtgc tggaggggct ggaatcggcc
    19501 aatgcctaca gcaccctgtc cctggacgtc ccggacacgg acgacgagtc cccggcggtc
    19561 gcggacacgc tgggctcgga ggacgaggcg ctggagggcg tcgagtaccg ggagtccctc
    19621 aagccgctgc tggaggggct gccaccgcgg gagaagcgga tcctgctgct gcggttcttc
    19681 gggaacatga cccagtcgca gatcgcgcag gaggtcggca tctcgcagat gcacgtctcc
    19741 cgcctgctgg cccggaccct ggcccagctc cgggagaagc tcctcgtcga ggagtagccg
    19801 caggggctat cgggtccgct cgccgggccc gattcccaga gcctcggtcg ccgtcgggtt
    19861 caccagcagg gccacgacgg ccacggccgc cagcgccaga cccacggcgg cggcggccat
    19921 cgccccgccc gtggtccaca gggtccacgc caccgggagc gccatcagct gggtgatcag
    19981 cgccgggccg cggctccagc ggcggcccag gcgcagcccg cgggccgcga tcagcggcag
    20041 cgcggcgagc gcgagcaggg tcacgccccc ggtctcggcc tgctgcgggg agtcggggtc
    20101 gccggcgatg cccacgaaca gcatgtagac gccgaggccg gccagcgcca ggccctccag
    20161 cgcggtgagc gcggcggcgg cggtcagccg gccgggcagc gcggcggcag cggcacccgt
    20221 accggtcgca ccggtcgctt cggtcgcggg ggcattcgag gcaggcttct tactcacccc
    20281 agcagggtag ccgcgccccg ccggcccggg aggggacggc cagtatgggt cgcccgtgga
    20341 cgggtgggta ggctggcgct catgcgtgca cttctcgtgg ccaacccagc agcgaccacc
    20401 accagtgcgc gcacgcgtga cgtcctgacc cacgccctgg ccagcgagat gaagctggag
    20461 gcggtcacca ccgagtaccg cggccacgcc cgggacctcg gccgcaaggc ggccctggag
    20521 ggcatggacc tggtggtcgc gctcggcggc gacggcaccg tcaacgaggt ggtgaacggg
    20581 ctgctgcacg acgggcccga cccggagcgg ctgccgaggc tggcggtggt ccccggcggc
    20641 tccaccaatg tgttcgcccg cgcgctcgga ctgcccaacg acgcggtcga ggcgaccggc
    20701 gccctgctgg acgcgctgcg ggagcggcgc gagcggacgg tgggcctggg cctggcgggc
    20761 ggcaccccgg gcacggcgga cgagtcggtt ccggagcgct ggttcacctt ctgcgcgggc
    20821 ttcggcttcg acgcgggtgt ggtggggcgg gtcgagcagc agcgggagcg cggcaagcgt
    20881 tcgacgcacg ccctctatgt acgacagctc gtgcgccagt tcctggagga gccgaaccgg
    20941 cggcacggca cggtcacgct ggagcggccc ggcgaggatc cggtgccgga tctggtgctg
    21001 tccatagtct gcaacacctc gccgtggaca tacctgggca atcgtccgct gtacgcctct
    21061 cccgacgcat cgtt
//
