LOCUS       NZ_BMUU01000043         3668 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence43, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000043
VERSION     NZ_BMUU01000043.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 3668)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 3668
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000043.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..3668
                     /culture_collection="JCM:4594"
                     /db_xref="taxon:67384"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces xanthochromogenes"
                     /strain="JCM 4594"
                     /submitter_seqid="sequence43"
                     /type_material="type strain of Streptomyces michiganensis"
     gene            complement(<1..>3668)
                     /db_xref="GeneID:96295720"
                     /locus_tag="IE233_RS38725"
     region          1..3668
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..3668
                     /SMILES="NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..3668
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:3668](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..3668)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             complement(<1..3668)
                     /NRPS_PKS="Domain: AMP-binding (72-475). E-value: 2.1e-117.
                     Score: 384.1. Matches aSDomain:
                     nrpspksdomains_IE233_RS38725_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (564-788). E-value: 6.9e-128. Score:
                     418.6. Matches aSDomain:
                     nrpspksdomains_IE233_RS38725_nMT.1"
                     /NRPS_PKS="Domain: PCP (992-1060). E-value: 5.3e-29. Score:
                     92.2. Matches aSDomain: nrpspksdomains_IE233_RS38725_PCP.1"
                     /codon_start=1
                     /db_xref="GeneID:96295720"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="IE233_RS38725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_190029702.1"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-128, bitscore:
                     414.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-18, bitscore:
                     53.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4e-42, bitscore:
                     130.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGAVEYSSDLYDASTVQSLFERWVRLLDEATAHPEQPLDTIDLL
                     TTEEQQQVLGTWLDTEAEVGADLLPARFARQARTTAEAVALITGDTSLTYGELNSRANR
                     LAHALLRQGAGPGTVIAVALPRSADLVAALLAVLKTGAAYLPLDPDHPAGRTAYVLADA
                     EPTLLLTTLATDARLPGDGSPRRLMLDSPDVQALVADCPDTDPSDADRTAPLYAADAAY
                     VIYTSGSTGRPKGVVVPHGALSNFLEAMRQNVPLRPDERLLAVTTVAFDIAALELYHPL
                     LSGAAVVLAPKEAVPQPSVVLDLIARHGVTVMQGTPSLWQLLVEHEPEALRGLRVLVGG
                     EALPAALAQSLRALTDDLTNLYGPTETTIWSTAADLSGATAAPPIGRPIANTRVYVLDG
                     RLQLVAPGVVGELYIAGAGVARGYLGRPALTAERFPADPYGSEPGARMYRTGDLVRWNP
                     GGELEFVGRADHQVKIRGFRIEPGEIEAVLTDHPAVAQAAVVVREDEPGDARLAAYVVA
                     DTSGRAYDENAELNQLSEWQDLYDSVYTSAPRTAFGENFASWNSSYDGQPIPLPDMREW
                     RDTTVERIRALGPRRILEIGVGTGLLLAGIAPGCEEYWGTDFSPTVIKDLQRHVDADPA
                     LASRVRLHTRPAHDFDGLPTGHFDTIVLNSVAQYFPSAGYLEQVVANALRALVPGGALF
                     IGDIRNPRLLRTFAAAVSAARAEDPSDTAAVRRAVEQSLVLEKELLVDPEYFTALAHHI
                     PDLAGTDIQLKRGTSHNELTRYRYDATLYKTGITPHPLTDTPTHPWPRHTDPGATLTDL
                     SRHLEAERPAGLRVTGVPNPRLTHELAVQHTLFDDIPASADSGRPQVTLEAFHALGDEH
                     GYWTGVTWSTHDHDAVDVLFVDRNLMDEGIPVGTYAPAGTGTSAMPLSTWTTNPAARRG
                     TGALVTELREHSRQHLPDYMVPAFIVPLDRLPLTANGKLDRAALPAPEFASGGSGREAR
                     TPQEQILCDLFAQVLGLPRVGVDDDFFQLGGHSLLATRLIAQARAVFGVELELRSLFEG
                     PTPAEVAALLDTAGPGRLALTRRERPETMPLSFAQRRLWFIHKMEGPSATYNIPLALRL
                     TGELDRDALRAALGDVVARHESLRTVFPEAEGVPFQQVLPVETAVPHLTVTPTTETELP
                     DLLTSASRHPFDLAAEPPLRADLFELSAEEHVLLIVVHHIAGDGWSLGPLASDLAGA"
     CDS_motif       complement(6..62)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS38725_0007"
                     /evalue="2.30E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE233_RS38725"
                     /protein_end="1221"
                     /protein_start="1202"
                     /score="26.5"
                     /tool="antismash"
                     /translation="VHHIAGDGWSLGPLASDLA"
     CDS_motif       complement(264..380)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS38725_0006"
                     /evalue="3.50E-21"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE233_RS38725"
                     /protein_end="1135"
                     /protein_start="1096"
                     /score="67.6"
                     /tool="antismash"
                     /translation="ATYNIPLALRLTGELDRDALRAALGDVVARHESLRTVFP"
     aSDomain        complement(489..692)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS38725_PCP.1"
                     /evalue="5.30E-29"
                     /label="IE233_RS38725_PCP.1"
                     /locus_tag="IE233_RS38725"
                     /protein_end="1060"
                     /protein_start="992"
                     /score="92.2"
                     /tool="antismash"
                     /translation="EQILCDLFAQVLGLPRVGVDDDFFQLGGHSLLATRLIAQARAVFG
                     VELELRSLFEGPTPAEVAALLDT"
     aSModule        complement(489..3452)
                     /complete
                     /domains="nrpspksdomains_IE233_RS38725_AMP-binding.1"
                     /domains="nrpspksdomains_IE233_RS38725_nMT.1"
                     /domains="nrpspksdomains_IE233_RS38725_PCP.1"
                     /locus_tags="IE233_RS38725"
                     /monomer_pairings="Gly -> NMe-Gly"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(1305..1976)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS38725_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="6.90E-128"
                     /label="IE233_RS38725_nMT.1"
                     /locus_tag="IE233_RS38725"
                     /protein_end="788"
                     /protein_start="564"
                     /score="418.6"
                     /tool="antismash"
                     /translation="GQPIPLPDMREWRDTTVERIRALGPRRILEIGVGTGLLLAGIAPG
                     CEEYWGTDFSPTVIKDLQRHVDADPALASRVRLHTRPAHDFDGLPTGHFDTIVLNSVAQ
                     YFPSAGYLEQVVANALRALVPGGALFIGDIRNPRLLRTFAAAVSAARAEDPSDTAAVRR
                     AVEQSLVLEKELLVDPEYFTALAHHIPDLAGTDIQLKRGTSHNELTRYRYDATLYKTGI
                     TP"
     CDS_motif       complement(2214..2279)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS38725_0005"
                     /evalue="6.70E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="IE233_RS38725"
                     /protein_end="485"
                     /protein_start="463"
                     /score="40.4"
                     /tool="antismash"
                     /translation="FVGRADHQVKIRGFRIEPGEIE"
     aSDomain        complement(2244..3452)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS38725_AMP-binding.1"
                     /evalue="2.10E-117"
                     /label="IE233_RS38725_AMP-binding.1"
                     /locus_tag="IE233_RS38725"
                     /protein_end="475"
                     /protein_start="72"
                     /score="384.1"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="FARQARTTAEAVALITGDTSLTYGELNSRANRLAHALLRQGAGPG
                     TVIAVALPRSADLVAALLAVLKTGAAYLPLDPDHPAGRTAYVLADAEPTLLLTTLATDA
                     RLPGDGSPRRLMLDSPDVQALVADCPDTDPSDADRTAPLYAADAAYVIYTSGSTGRPKG
                     VVVPHGALSNFLEAMRQNVPLRPDERLLAVTTVAFDIAALELYHPLLSGAAVVLAPKEA
                     VPQPSVVLDLIARHGVTVMQGTPSLWQLLVEHEPEALRGLRVLVGGEALPAALAQSLRA
                     LTDDLTNLYGPTETTIWSTAADLSGATAAPPIGRPIANTRVYVLDGRLQLVAPGVVGEL
                     YIAGAGVARGYLGRPALTAERFPADPYGSEPGARMYRTGDLVRWNPGGELEFVGRADHQ
                     VKIR"
     CDS_motif       complement(2367..2453)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS38725_0004"
                     /evalue="7.40E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="IE233_RS38725"
                     /protein_end="434"
                     /protein_start="405"
                     /score="56.6"
                     /tool="antismash"
                     /translation="PGVVGELYIAGAGVARGYLGRPALTAERF"
     CDS_motif       complement(2583..2621)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS38725_0003"
                     /evalue="3.60E+01"
                     /label="C3_DCL_135-156"
                     /locus_tag="IE233_RS38725"
                     /protein_end="362"
                     /protein_start="349"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="SLRALTDDLTNLY"
     CDS_motif       complement(2949..3008)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS38725_0002"
                     /evalue="6.70E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="IE233_RS38725"
                     /protein_end="240"
                     /protein_start="220"
                     /score="33.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVVVPH"
     CDS_motif       complement(3225..3266)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS38725_0001"
                     /evalue="2.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IE233_RS38725"
                     /protein_end="148"
                     /protein_start="134"
                     /score="17.5"
                     /tool="antismash"
                     /translation="LAVLKTGAAYLPLD"
ORIGIN
        1 gcacccgcca aatccgaagc caacggaccc aacgaccacc catcacccgc aatgtgatgg
       61 accactatca gcagcacgtg ttcctccgcc gacagctcga acaggtcggc gcgcagcggc
      121 ggttcggccg ccaggtcgaa ggggtggcgg gacgccgacg tgaggaggtc cggcaactcc
      181 gtctcggtcg tcggtgtgac ggtgagatgc ggtacggccg tttcgacggg cagcacctgc
      241 tggaacggaa ctccctcggc ctccgggaat accgtgcgca ggctctcgtg ccgggccacc
      301 acgtcgccga gtgcggcccg cagcgcgtcg cggtcgagct cgcccgtcag ccgcagggct
      361 agcggaatgt tgtaggtggc gctgggtccc tccatcttgt ggatgaacca cagtcgacgc
      421 tgagcgaagg acagcggcat ggtctcgggc cgctcgcgcc gtgtgagcgc cagccggccg
      481 ggcccagcgg tgtccaggag tgcggcgacc tcggccggtg tcggaccctc gaagagcgag
      541 cggagctcca gctcgacgcc gaagaccgcc cgggcctggg cgatgaggcg agtggccagg
      601 agcgagtgcc cgcccagctg gaagaagtcg tcgtccacac ccacccgcgg cagcccgaga
      661 acctgcgcga acagatcaca caagatctgc tcctgcggcg tacgcgcctc ccgccccgac
      721 ccacccgacg cgaactccgg cgccggcaac gccgcccggt ccaacttgcc gttcgccgtc
      781 agggggagcc ggtcgagggg gacgatgaac gcggggacca tgtagtcggg cagatgctga
      841 cggctgtgtt cgcggagttc ggtgacgagg gcgccggtgc cgcggcgggc ggccgggttg
      901 gtcgtccagg tggacagcgg catggccgag gtgcccgtac cggcaggggc gtaggtgcct
      961 acggggatgc cttcgtccat gaggttccgg tcgacgaaca ggacgtccac ggcgtcatgg
     1021 tcgtgagtgc tccaggtgac gccggtccag tagccgtgct cgtcgcccaa agcgtggaag
     1081 gcctccagcg tgacctgcgg ccggccgctg tccgcggacg caggtatgtc gtcgaagagg
     1141 gtgtgctgaa cggccagctc gtgcgtgagg cgagggttcg ggacgccggt gacgcggagc
     1201 ccggcggggc gctcggcttc gaggtgacgg ctcagatcgg tgagggtggc gccggggtcg
     1261 gtgtgccggg gccaggggtg ggtgggggtg tcggtgaggg ggtggggggt gatgccggtc
     1321 ttgtagaggg tggcgtcgta gcggtagcgg gtgagctcgt tgtgggaggt gccgcgcttg
     1381 agctggatgt cggtgccggc caggtcgggg atgtggtggg cgagggcggt gaagtactcc
     1441 gggtccacca ggagttcctt ctccaggacg agactctgct ccacggcacg gcggacggcg
     1501 gccgtgtccg aagggtcttc ggcgcgcgcg gcactgaccg cggcggcgaa ggtgcgcagc
     1561 agccgcgggt tgcggatgtc gccgatgaag agggctcccc cggggaccag cgcgcggagg
     1621 gcgttggcga cgacctgctc caggtagccg gcgctcggga agtactgggc gaccgagttg
     1681 aggacgatcg tgtcgaagtg gcccgtggga aggccgtcga agtcgtgggc gggccgggtg
     1741 tgcagacgga cccgggaggc gagggcggga tcggcgtcga cgtggcgctg caggtccttg
     1801 atgacggtgg gcgagaagtc ggttccccag tactcctcgc acccgggggc gattccggcg
     1861 aggagcagtc cggtgcccac gcctatttcg aggatgcggc gagggccgag ggccctgatg
     1921 cgttcgacgg tcgtgtcgcg ccactcccgc atgtcgggca gcgggatggg ctgtccgtcg
     1981 taactgctgt tccagctggc gaagttctcg ccgaacgccg tcctgggtgc gcttgtgtag
     2041 acggagtcgt acaggtcctg ccactcgctc agctggttca gctcggcgtt ctcgtcgtac
     2101 gcgcgtcccg aggtgtcggc gacgacgtag gcggccagcc gggcgtcccc gggctcgtcc
     2161 tcgcggacga cgacggcggc ctgggcgacg gcgggatgat cggtcaacac ggcctcgatc
     2221 tcgccgggtt cgatgcggaa cccccggatc ttgacctgat ggtcggcccg gcccacgaac
     2281 tccagctcgc cgcccggatt ccagcgcacc aggtccccgg tgcggtacat gcgggcgccg
     2341 ggctcactgc cgtaggggtc ggccgggaag cgttccgcgg tcagggcggg gcggcccagg
     2401 tagccgcggg ccacgccggc gcccgcgatg tacagctccc ccaccacgcc cggagccacc
     2461 aactgcagcc ggccgtccag gacgtacacc cgggtgttgg cgatcggccg gccgatgggc
     2521 ggggctgccg tggcgccgga gaggtcggcg gcggtcgacc agatggtggt ttcggtcggc
     2581 ccgtacaggt tggtgaggtc gtccgtgagg gcccgcagcg actgggccag ggcggcgggc
     2641 agcgcctctc cgccgaccag aacgcgcagt ccgcgcaagg cctccggctc gtgttcgacc
     2701 agcagttgcc acagggacgg cgttccctgc atgaccgtga caccgtgccg ggcgatcagg
     2761 tcgagcacga cggacggctg ggggacggcc tccttgggcg cgagaacgac cgcggcaccc
     2821 gagagcagcg ggtggtacaa ctccagggcg gcgatgtcga aggcgaccgt cgtgaccgcg
     2881 agcagccgct cgtccggccg gagcggcacg ttctgccgca tggcttccag gaagttggac
     2941 agcgcgccgt gcggcaccac cacacccttg gggcggccgg tcgagccgga cgtgtagatc
     3001 acatatgcgg cgtccgcggc gtacagcggg gcggtgcggt cggcgtcgga cgggtcggtg
     3061 tcggggcagt cggcaaccag cgcctgtacg tccggtgagt ccagcatcag ccgccgcggc
     3121 gagccgtcgc ccggcaaccg cgcgtccgtc gccagagtgg tgagcagcag ggtgggttcc
     3181 gcgtccgcca ggacgtacgc ggtgcgcccg gccggatggt ccgggtccag cggcaggtag
     3241 gcggcgccgg tcttgagcac cgccaggagg gcggccacca ggtcggccga gcgcggcagg
     3301 gcgacggcga tcaccgtgcc cggtcccgcg ccttggcgca gcagggcgtg cgccaggcga
     3361 ttggcgcggc tgttcagttc cccgtacgtc agggaggtgt ccccggtgat cagggcgacg
     3421 gcctccgccg tggtccgcgc ctgcctggca aagcgcgccg gcaacaggtc cgcaccgact
     3481 tccgcctcgg tgtccagcca ggtgccgaga acctgttgtt gctcttcggt ggtgaggaga
     3541 tcgatggtgt cgagtggctg ctcgggatgg gcggtcgcct cgtcgaggag cctgacccag
     3601 cgctcgaaca gcgactgcac ggtggacgcg tcatacagat cgctggagta ctcgaccgcc
     3661 cccacgat
//
