LOCUS       NZ_BMUU01000021        21032 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence21, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000021
VERSION     NZ_BMUU01000021.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 85930)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4446
            Orig. end                         :: 25478
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21032
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21032
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21032
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11032](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11032
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            449..883
                     /db_xref="GeneID:96295228"
                     /locus_tag="IE233_RS36190"
                     /old_locus_tag="GCM10010326_73840"
     CDS             449..883
                     /codon_start=1
                     /db_xref="GeneID:96295228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889332.1"
                     /locus_tag="IE233_RS36190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73840"
                     /product="hypothetical protein"
                     /protein_id="WP_190029404.1"
                     /transl_table=11
                     /translation="MSTEQTPEASAEPRPGRLTAAAALSALEGLALVAGGLFMLVMGLT
                     GKPDKPTQAEMGGLTLVVLGLIPLIAARGLLRRRSWSRGPAMITQIMALPVAWMFLNSD
                     GAPWIPAGIALAAVAITGLVLLVNPATTEALGIRGPMRDA"
     gene            complement(941..1891)
                     /db_xref="GeneID:96295229"
                     /locus_tag="IE233_RS36195"
                     /old_locus_tag="GCM10010326_73850"
     CDS             complement(941..1891)
                     /codon_start=1
                     /db_xref="GeneID:96295229"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136656.1"
                     /locus_tag="IE233_RS36195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73850"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_161258181.1"
                     /transl_table=11
                     /translation="MSGEGPVRDDERTPEAVRPVGIPEQQARPHPVDSPVDGPDGVLYA
                     AEQAERAALMSEHIEHRHHDPHDRSGARAMFFELRKLPDGSSEKAELRNQLVRMHLPLV
                     EHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDK
                     GWAVRVPRRLQELRLALTTATAELSQQHGRSPTVHELAERLGISEEEVLEGLESANAYS
                     TLSLDVPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNM
                     TQSQIAQEVGISQMHVSRLLARTLAQLRDKLLVEE"
     gene            complement(1888..2301)
                     /db_xref="GeneID:96295230"
                     /locus_tag="IE233_RS36200"
                     /old_locus_tag="GCM10010326_73860"
     CDS             complement(1888..2301)
                     /codon_start=1
                     /db_xref="GeneID:96295230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="IE233_RS36200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73860"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_161258184.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVESTVAEDRTVSISLYKQRGAGPGPA"
     gene            complement(2601..2861)
                     /db_xref="GeneID:96295231"
                     /locus_tag="IE233_RS36205"
                     /old_locus_tag="GCM10010326_73870"
     CDS             complement(2601..2861)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="IE233_RS36205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73870"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_161258187.1"
                     /transl_table=11
                     /translation="MSECPHVAELPRPEPAPLNDTCPECLKDGTHPVQLRLCLVCGHVG
                     CCDSSPHQHATGHFEETGHAVMRTFEPGESWRWCFVDGLLV"
     gene            2918..4516
                     /db_xref="GeneID:96295232"
                     /locus_tag="IE233_RS36210"
                     /old_locus_tag="GCM10010326_73880"
     CDS             2918..4516
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521043.1"
                     /locus_tag="IE233_RS36210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73880"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_161258189.1"
                     /transl_table=11
                     /translation="MDALPLVALIAASAAVAGAARRSPVPAPLLLVAVGLIGAYVPGVP
                     AYTLDPHIVLPLVLPPLLHTAALESSYLDLRANLRPVALLSVGYTLFATVAVGYLAYLL
                     VPDLPLTAALVLGAVIAPPDAVAATAIARRLRLPSRITTILQGESLVNDATAITAYKVA
                     LAAAVGAGATWGGGVKEFALASIGGVGVGLVLMLPIHWLRRHLHEALLQNTLSLLIPFV
                     AYAAAEQVGASGVLAVVVVALYLGHRSWQVDFATRLQEEAVWKMVSFLLESAVFALIGL
                     QMPVVLKGLGEYGVGEAVWYAIGVFVLVVAARFVWVFPATFLPRALSEKIRRREPETDW
                     TAPVIVGWAGMRGVVSLAIAFSIPLTMADGSAFPARNLVLFLTFTTVIGTLVVQGLTLP
                     PLIRLLKLPGRDTQAETLAEAQAQSEASRAAEARLDELLADPRSTLPPPLADRLRTVLE
                     RRRNAVWERLGAVNEVTGESADATYRRLSREMIEAERKVFVSLRDDRRIDDEMMRTLLR
                     RLDLEEAAAYRDPGT"
     gene            complement(4974..5855)
                     /db_xref="GeneID:96295233"
                     /locus_tag="IE233_RS36215"
                     /old_locus_tag="GCM10010326_73890"
     CDS             complement(4974..5855)
                     /codon_start=1
                     /db_xref="GeneID:96295233"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892047.1"
                     /locus_tag="IE233_RS36215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73890"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_161246047.1"
                     /sec_met_domain="PALP (E-value: 9.4e-19, bitscore: 60.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPEALAPRLPSPLEEVTDERFARHGVRLLLKRDDLIHPALVGNK
                     WRKLVPNLRAAAGRPVLTFGGAYSNHLRATAAAGRLLGFPTIGVVRGDELAGRPLNDSL
                     ARCAADGMRLHFVDRATYRRKSDPEVLAGLLGLLAPGAYVVPEGGSNSLAAQGCTELGA
                     ELRGPTDVAAVACGTGGTLAGLAAGLGPAQRAIGVPVLKGGFLAGEVDALQRAAFGGPR
                     GTWTLDDRFHFGGYARVPPELEAFARDFEDRHGVGVERVYVAKVLFALHALTQEGSFTP
                     GTTLTAVITGRP"
     gene            complement(5885..6475)
                     /db_xref="GeneID:96295234"
                     /locus_tag="IE233_RS36220"
                     /old_locus_tag="GCM10010326_73900"
     CDS             complement(5885..6475)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437931.1"
                     /locus_tag="IE233_RS36220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73900"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_161246045.1"
                     /transl_table=11
                     /translation="MAPPMSADQFLAALRAEGLRVVEVGQWRTHNRAGHGGWAPINGVV
                     IHHTATSGADATVRICYDGYDSLPGPLCHGVITKDGTVHLVGNGRANHAGAGDGNVLRA
                     VIAEKRLPQPLTNDTDGNTHFYGFECENLGDGKDPWPEAQLEAIEKAAAAVCRHYGWTE
                     RSVIGHKEWQVGKIDPRGFTMDWLRERVHERLK"
     gene            complement(6603..7793)
                     /db_xref="GeneID:96295235"
                     /locus_tag="IE233_RS36225"
                     /old_locus_tag="GCM10010326_73910"
     CDS             complement(6603..7793)
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295235"
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154134.1"
                     /locus_tag="IE233_RS36225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73910"
                     /product="globin domain-containing protein"
                     /protein_id="WP_161246043.1"
                     /transl_table=11
                     /translation="MLSEKSTVTVRATLPAVGAAIGTITERFYERLFADRPALLRDLFN
                     RGNQAAGLQKQALAGSIAAFATHLVDHPEERPDVMLNRIAHKHASLGVTADQYEIVHRH
                     LFAAIAEVLGEAVTAVVAAAWDEVYWLMANALIDIEARLYAEQGVLAGDVWREWTVAGR
                     TEETASCATFRLRPADGAPAPASKPGQYVSVQVELPDGARQIRQYSLTSAPGGELRSIT
                     VKRVQGDPDGEVSGHLHAHLREGDRLRVSAPYGDLVLDADGSPLLLASAGIGCTPMVAM
                     LGQLAADGHRAPVTVVHADRSPAEHALRDDHAALTAQLPDSTAHFWYEDPEPGHPADRT
                     GLVDLTRLPVAPGTRAYLCGPLPFMRAVRTQLLAKGVRAADVHYEVFGPDLWLAQD"
     misc_feature    7853..7867
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            complement(7911..8354)
                     /db_xref="GeneID:96295236"
                     /locus_tag="IE233_RS36230"
                     /old_locus_tag="GCM10010326_73920"
     CDS             complement(7911..8354)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611275.1"
                     /locus_tag="IE233_RS36230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73920"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_190029405.1"
                     /transl_table=11
                     /translation="MRLTRFTDLALRVLMRLAVIENAADQVPPTTREVADAMRIPYTHT
                     AKVVARLQHLGLVEARRGRGGGLAVTAAGHLVPVGGLVRELEGPGDVVECEGATPCPLA
                     AACRLRRALHRAQEAFYESLDELTVDDLVTAPTGPLLLGITSR"
     gene            8527..9924
                     /db_xref="GeneID:96295237"
                     /locus_tag="IE233_RS36235"
                     /old_locus_tag="GCM10010326_73930"
     CDS             8527..9924
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639605.1"
                     /locus_tag="IE233_RS36235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73930"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_190029406.1"
                     /transl_table=11
                     /translation="MSVEAGPENRTQQSLGTAAARNLATTTKSAPQMQEITSRWLLRML
                     PWVQVQGGTYRVNRRLSYSVGDGRITFVQTGERVAVIPAELGELPALRDYEDEAALGEL
                     ANRCEQREYAAGEVIATAGDATDRVFLLAHGRVEKIGTGQYGDETELGFLADGAHFGED
                     ALVSGEAVWECTYRATTGCTVLVLSRADVLNLAERSESLHDHLASVTGLPEQRTNNYGE
                     AAIDLSAGHVGEAIIPHTYVDYEGSPREYELSVAQTVLKVHSRVADLYNQPMNQTEQQL
                     RLTVEALRERQEYELVNNREFGLLTNCDYEQRLQPHDGVPGPDDMDELLSRRRGSKLFL
                     AHPRAIAAFGRECNKRGLVPESVEVAGHHVPAWRGVPIFPCNKIPVSDARTTSIICMRT
                     GEAEQGVIGLQQSGIPDEIEPSLSVRFMGIDEQAIISYLVTAYYSAAILVPDALGVLEN
                     VEVSRWR"
     gene            10001..11032
                     /db_xref="GeneID:96295238"
                     /locus_tag="IE233_RS36240"
                     /old_locus_tag="GCM10010326_73940"
     CDS             10001..11032
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295238"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959111.1"
                     /locus_tag="IE233_RS36240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73940"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_161257802.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.4e-62, bitscore:
                     203.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEAMEGREAGDLLERARTVVDPQLRASVASLPGSMRRVAMYHFG
                     WEHADGTPAGGQSGKAIRPALVLAAATALGGRPEAAVRAAAAVELVHNFTLLHDDVIDE
                     DATRRHRPTAWTVFGTPDAIIVGDALFALALRLIADDGHPASGAASARIAACVIELCAG
                     QQADCAFEQRGPQDVSLDECIAMAMAKTGALLGCACALGALYAGAGDEEVAAMDAFGRE
                     AGLAFQLIDDLIGIWGDPGRTGKPAGADLAAHKKSLPVVAALNSGTPAAAELAELYGGP
                     MGAEAVRRAADAVDRAGGRDWAQVHAADRMARAVDHLSRAVPDLTAAGELLALAEFVTR
                     RTR"
     gene            11169..12392
                     /db_xref="GeneID:96295239"
                     /locus_tag="IE233_RS36245"
                     /old_locus_tag="GCM10010326_73950"
     CDS             11169..12392
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295239"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119575.1"
                     /locus_tag="IE233_RS36245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73950"
                     /product="MFS transporter"
                     /protein_id="WP_190029407.1"
                     /transl_table=11
                     /translation="MTSRLLPPAGPARGLATAQLVNSLGDGAFLVTSALYFSRVVGLPA
                     TRIGLGLTLAWAVGALAGVPLGQLADRRGPRTVAVLLAAATGASVASFLFVRGFLPFVL
                     AACCYATAQTGLSAARQALLSALVDRGDRTRVLAHLQSTLNAGLAVGAAFGGVALHYGT
                     RTAYLAVFALDAVAFLFCALALMRLPHVPPRPVVPGGGPRFAVLRDRPYAVITFLNTLL
                     LLRMPLISLAVPLWTVTRTDAPGWLVSALLVLNTGAVMLFQVRTASAVRDLPSARRTVA
                     RGGVLMLASCAAFALSAAGASPWAAVGVLLVAGGLQVAGEMMQSAGAWQIGFDLAPADQ
                     QGQYQGFFGMGVPLARMLGPLLLTALVIDWGVPGWLVLGALFLGAGLALGPAVRWAERS
                     NSALVAAG"
     gene            12518..12964
                     /db_xref="GeneID:96295240"
                     /locus_tag="IE233_RS36250"
                     /old_locus_tag="GCM10010326_73960"
     CDS             12518..12964
                     /codon_start=1
                     /db_xref="GeneID:96295240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127496.1"
                     /locus_tag="IE233_RS36250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73960"
                     /product="DUF6304 family protein"
                     /protein_id="WP_161257808.1"
                     /transl_table=11
                     /translation="MTPQSWAGWYRDRLGSEALTITTDGTQLRTRIRGVDFAGASFDSL
                     GPVPGIPTESGAFALDDGNLRDFVLEWDMPVPIASDDGAVQEATLSCLLSLKPPEPDLG
                     VALHFGGAVYASGRAEVDFGSVLADIRRQLPSGSSLQPSALDAI"
     gene            13138..14112
                     /db_xref="GeneID:96295241"
                     /locus_tag="IE233_RS36255"
                     /old_locus_tag="GCM10010326_73970"
     CDS             13138..14112
                     /codon_start=1
                     /db_xref="GeneID:96295241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105593.1"
                     /locus_tag="IE233_RS36255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73970"
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_161257811.1"
                     /transl_table=11
                     /translation="MIRVRHRLTAVAALPFLLALAVDLTLYVLLHDRLPDPLASHFTGN
                     GRSDGTQSRGSAPVFACVLHLGLGALWAGMAAVGGPAVRRLRWLIAAGYATAGFVGYLL
                     AATLLANADATDPARVRLPLWQIAVGAGVAVLAAALGRLLLMALPTPPPEPSSRPDADR
                     TPRLDLAEGEVAGWMRRAPSRVLLVCGALLFVAAGALLFALGPSHGVGALFGAVVCLVF
                     SCPYVTVDRRGLTARPTALPWPRIRIPLSDVDRAVSRDIKVLAEYGGWGYRTRAGRSGL
                     MLRSGEAIVIRRSDGREFAVTVDDAGTAAALLNTLARRAEARD"
     gene            14112..14468
                     /db_xref="GeneID:96295242"
                     /locus_tag="IE233_RS36260"
                     /old_locus_tag="GCM10010326_73980"
     CDS             14112..14468
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295242"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009068650.1"
                     /locus_tag="IE233_RS36260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73980"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_190029408.1"
                     /transl_table=11
                     /translation="MLFRVDPASPRPLGDQIAASVRGAIADGKVAPGERLPPARSLADL
                     LGVNVHTVLRGYQRLRDEGLIELRRGRGAVVVDDTRARGRAELMLRVRELVDQARELGL
                     TEDEVVGLVRRGLA"
     gene            complement(14509..14919)
                     /db_xref="GeneID:96295243"
                     /locus_tag="IE233_RS36265"
                     /old_locus_tag="GCM10010326_73990"
     CDS             complement(14509..14919)
                     /codon_start=1
                     /db_xref="GeneID:96295243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523291.1"
                     /locus_tag="IE233_RS36265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_73990"
                     /product="glyoxalase/bleomycin resistance/extradiol
                     dioxygenase family protein"
                     /protein_id="WP_190029409.1"
                     /transl_table=11
                     /translation="MDPLEPPYPRLLVDPYEPAFRFYDAVLPDLTGCTLARGNSASGYA
                     SWDAPDGRTALALFTRSAMAAVLGEDRMPGGGASLVIHVATRDALDAAVSLCAKAGGTV
                     AVPVRDLPEWGPGMRAAHLLDPAGNLVELQTY"
     misc_feature    14956..14971
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            complement(14967..15548)
                     /db_xref="GeneID:96295244"
                     /gene="cpt"
                     /locus_tag="IE233_RS36270"
                     /old_locus_tag="GCM10010326_74000"
     CDS             complement(14967..15548)
                     /codon_start=1
                     /db_xref="GeneID:96295244"
                     /gene="cpt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126766.1"
                     /locus_tag="IE233_RS36270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_74000"
                     /product="chloramphenicol phosphotransferase CPT"
                     /protein_id="WP_190029435.1"
                     /transl_table=11
                     /translation="MIVLNGGSSSGKSGIVRCLQAVLPGAWLAFGVDSVDAAMPASLRG
                     EGGLEIGADGTVTVGPDYRRLSDAWARGVAAMVRAGAHVVLDEVFLDGADAQKRWQQAL
                     DGLDVLWVGVRCDPDTAAGRETARGDRVPGMARGQAESVHAGVRYDIEVDSAGAESMAC
                     ARLIAERYARPARAGAPERARSGSGPGRDA"
     gene            15647..16204
                     /db_xref="GeneID:96295245"
                     /locus_tag="IE233_RS36275"
                     /old_locus_tag="GCM10010326_74010"
     CDS             15647..16204
                     /codon_start=1
                     /db_xref="GeneID:96295245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742825.1"
                     /locus_tag="IE233_RS36275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_74010"
                     /product="adenylate kinase"
                     /protein_id="WP_161257821.1"
                     /transl_table=11
                     /translation="MRRILVVGSTGAGKSTLAHELGERLGVPYHELDALHFTGPGWAQD
                     PDFAARVAEIAATPAWVLDSYGTPDVRPLLWERADTVVWLDYPRHVVMPRVLRRSLRRT
                     VLRERIFNGNRETLTEWFRGDHPARWAWSQYAPRRAALTALTTDPALAPLHTLRFTAPR
                     EARRWLRTIEAGRGERRKGPAG"
     gene            complement(16278..16673)
                     /db_xref="GeneID:96295246"
                     /gene="sodN"
                     /locus_tag="IE233_RS36280"
                     /old_locus_tag="GCM10010326_74020"
     CDS             complement(16278..16673)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295246"
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="IE233_RS36280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_74020"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_053730656.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKFQAN
                     EDAHFRARAVVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKA
                     STDPATGQKALDLIAEIDRIFWETKKA"
     gene            16849..17274
                     /db_xref="GeneID:96295247"
                     /gene="sodX"
                     /locus_tag="IE233_RS36285"
                     /old_locus_tag="GCM10010326_74030"
     CDS             16849..17274
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295247"
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892065.1"
                     /locus_tag="IE233_RS36285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_74030"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_190029410.1"
                     /transl_table=11
                     /translation="MTDEGREPRVPLGIAEVLGTSMVPTLLHGDQLLVHYGAELRIGDV
                     AVLRHPLQQDLLIVKRLMELRESGWWVLGDNTDDEVVDSRAFGAVPVDLVLGRVRGRFR
                     PMAAGRRRTIGYLASWAVSSVRPVLSDRSVSRRLRAR"
     gene            complement(17193..17807)
                     /db_xref="GeneID:96295248"
                     /locus_tag="IE233_RS36290"
                     /old_locus_tag="GCM10010326_74040"
     CDS             complement(17193..17807)
                     /codon_start=1
                     /db_xref="GeneID:96295248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="IE233_RS36290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_74040"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_161257826.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPARNKDALTSVEAVRDLFGGNQSAARR
                     ATDADVTRFRSVRARLRAVFEAADRGEEVQAVDLLNSLLLEFPVSPQVSGHEHRDDDGR
                     PLWHMHLADHPSNATAGYAAIASMGLAFHLTEYGVDRLGLCQAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLETERSDSTGLTEETAQDAR"
     misc_feature    17800..17815
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    17863..17878
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: medium, score: 26.18"
                     /tool="antismash"
     misc_feature    complement(17863..17879)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 24.89"
                     /tool="antismash"
     gene            17993..18682
                     /db_xref="GeneID:96295249"
                     /locus_tag="IE233_RS36295"
                     /old_locus_tag="GCM10010326_74050"
     CDS             17993..18682
                     /codon_start=1
                     /db_xref="GeneID:96295249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236239.1"
                     /locus_tag="IE233_RS36295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_74050"
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="WP_229893076.1"
                     /transl_table=11
                     /translation="MPDREERFRVMLDMVEACVGPAPRVLDLACGTGSITDRLLRRFPD
                     AVSTGVDLDPALLAIAEGTFAGDERVTFVAADLKDPHWVQSLPYDSYDAVLTATALHWL
                     HAEPLAALYGQVAGLVRDGGVFMNADHMIDPATPRINAAERAHRHAGMDRAKAGGALDW
                     AQWWELAAADPALAGPTAKRYEIYGEHADGDMPAAGWHAETLRAAGFAEARPVWASPSD
                     TLLLALK"
     gene            complement(18741..19508)
                     /db_xref="GeneID:96295250"
                     /locus_tag="IE233_RS36300"
                     /old_locus_tag="GCM10010326_74060"
     CDS             complement(18741..19508)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295250"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="IE233_RS36300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_74060"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_190029412.1"
                     /transl_table=11
                     /translation="MTAQPMVKAEGVHKSFGPAHILKGIDLEVAEGEVFCLIGPSGSGK
                     STFLRCINHLEQINAGRLYVDGELVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLF
                     PHMTAVENVMEAPVQVKREPKAVARERALKLLDRVGLADKAGNYPSQLSGGQQQRVAIA
                     RALAMDPKLMLFDEPTSALDPELVGDVLDVMRGLAEDGMTMIVVTHEMGFAREVGDSLV
                     FMDDGVVVEAGHPRDVLTNPQHDRTKSFLSKVL"
     gene            complement(19513..20445)
                     /db_xref="GeneID:96295251"
                     /locus_tag="IE233_RS36305"
                     /old_locus_tag="GCM10010326_74070"
     CDS             complement(19513..20445)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96295251"
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142340.1"
                     /locus_tag="IE233_RS36305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_74070"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_161253335.1"
                     /transl_table=11
                     /translation="MTDKLDKTPGPADAAPEQVPPDIIRAIPVRHYGRWVSAVVVVAVL
                     GALVYAFAQGNVRWATVTDKLFDGSILTGLWHTILISVVSMAVGLVLGVLFAVMRLSKN
                     PVTSSVAWLYIWFFRGTPVYVQLLIWFNLALIFPILNLGFYKDYMTAVMTPFLAALLGL
                     GLNEGAYMAEIVRAGIQSVDEGQTEASHALGMTQMQTMRRVVLPQSMRVIIPPTGNEFI
                     NMLKTSSLVVAVQYQDLLRSAQDVAATSFAVMEMLFVASIWYLALTSVFSVGQYYLERR
                     FARGSLRSLPPTPLQRIKSNLLSLSHWRR"
     misc_feature    20718..20732
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.83"
                     /tool="antismash"
ORIGIN
        1 cgcgtcgaga atgacaccgg tcgactccac agcgtcattg ggcagaccga gcgcccgcgc
       61 gaacacattc gtcgaaccgc cgggaaccac ggcgaattcg gggagttcgg ggctcggccc
      121 gttgtgcagc agaccgttca cgacctcgtt gaccgtgccg tcgccgccga gcgccaccac
      181 gagatcgatg tcactgctct cggcggcccg ccggccgagg tccttcgcgt gcccgcggta
      241 ctcggtggtg accgcctcca gcttcatctc gctggccagc gcgtggatca ggacgtcacg
      301 cgtgcgcgca ctggtggtgg tagccgccgg gttgaccacg agaagtgcac gcatgggcgc
      361 cagactacct accggggggt accggggcgc acctgggccg gaccgcccgc cccggggcgg
      421 ggccccgcgc ccgggctacc ctggccgggt gagtactgag cagacccccg aagcctccgc
      481 cgaaccgcgc cccggccggc tgaccgccgc ggcggcgctg tccgcgctgg aggggctcgc
      541 cctggtcgcc ggtgggctct tcatgctcgt gatgggcctg accggcaagc cagacaagcc
      601 cacccaggcc gaaatgggcg gcctgacgct ggtggtcctc ggcctgatcc cgctgatcgc
      661 cgcccgcgga ctgctgcgcc gccgcagctg gagccggggc ccggcgatga tcacccagat
      721 catggcgctg ccggtggcgt ggatgttcct caactccgac ggggcgccct ggatcccggc
      781 cggcatcgct ctcgcggcgg tggccatcac cggtctcgta ctcctggtga acccggccac
      841 caccgaggcg ctgggcatcc gcgggccgat gcgggacgcg tgagcgcgaa gggtccgcgg
      901 gcgcgccccc ggaccccgtc cgctccgcca cgcgaagcgg ctactcctcc acgaggagct
      961 tgtcccgcag ctgggccagg gtgcgggcca gcaggcgcga gacgtgcatc tgcgagatgc
     1021 cgacctcctg cgcgatctgt gactgggtca tgttgccgaa gaaccggagc agcagaatcc
     1081 gcttctcccg cggcggcagg tcttcaagca gcggcttgag ggactcgcgg tactcgacgc
     1141 cttcgagcgc ctcgtcctcc gcgcccaggg tgtccgcgac cgcgggcgac tcgtcgtccg
     1201 tgtccggcac gtcgagggag agcgtggaat aggcgttggc cgactccagc ccctccagga
     1261 cctcttcctc cgagatgccg agccgctccg ccagttcgtg caccgtgggc gagcggccgt
     1321 gctgctggga cagctccgcc gtcgccgtgg tgagcgcgag ccgcagctcc tggagccggc
     1381 gcggcacccg caccgcccag cccttgtcac ggaagtgccg cttgatctcg ccgacgacgg
     1441 tgggcgtcgc atacgtcgag aactcgacgc cccgctcggg gtcgaaccgg tccaccgact
     1501 tgatcagacc gatcgtggcg acctgggtca gatcgtcgag gggctcgcca cggttgcgga
     1561 agcgccgggc caggtgctcg accagtggca ggtgcatccg aaccagctga ttgcgcagct
     1621 ccgccttctc ggacgagccg tcgggcagct tgcgcagctc gaagaacatc gcccgcgccc
     1681 cgctgcgatc gtgtggatcg tgatgcctgt gctcgatgtg ctcgctcata agggccgccc
     1741 gctctgcctg ctccgccgcg tacaaaacgc catctgggcc atccacaggg ctgtcgaccg
     1801 ggtgcggccg ggcctgctgc tccgggatgc ccacggggcg caccgcttcc ggagtgcgct
     1861 cgtcgtcccg caccggaccc tccccgctca cgccggtccg ggtcccgcgc cgcgctgttt
     1921 gtacaggctg atggagaccg tacggtcctc ggccacggtg gattcgacct tgccggccag
     1981 ggcggagagc accgtccacg cgaaggtgtc gcgctccggg gcccggccgt cggtggtcgg
     2041 cgccgagacg gtgacctcca acgagtcgtc cacgaggcgg aagacgcagc tcagtacgga
     2101 acctggaacg gcctgctgga gcaggatcgc gcaggcctcg tcgaccgcga tgcgcagatc
     2161 ctcgatctcg tcgagggtga agtccaaacg tgccgcgagt ccggccgtgg ccgtacgcag
     2221 caccgacagg taggcacccg cggccggcag ccggacttcc acgaagtcct gattcccggg
     2281 ctcgcctgcg atctgggaca ccctcacctc caaggtggca caagctctct cgaggcccaa
     2341 ggagggggga agtcccgggg ccgtgggtac gggggtccgt acctggactg gcgacgctat
     2401 cgcgatccat ggtgccctgt cgccggaagc tctcccggcg actgtcactc atggtaagcc
     2461 tatgagtacg gacagtggct agaggtttgc agtgcccaat tgcggtgaag cgggaccggg
     2521 ttgacgtacc caggcgccgg gcgcttcgaa ccttcccgta cgtctcttac gcatcggacg
     2581 tggaacgcgg gaggccactc tcacaccagc aggccgtcca cgaagcacca gcgccagctc
     2641 tcgccgggct cgaaggtccg catcaccgcg tgaccggtct cctcgaagtg gcccgtggcg
     2701 tgctggtgcg gcgaggagtc gcagcagccc acgtgcccgc agaccaggca cagacgcagt
     2761 tgtacggggt gcgtaccgtc cttcaggcac tccgggcagg tgtcgttcag cggggccggc
     2821 tcggggcgcg gcagttctgc aacgtgcggg cactcgctca tgatggccag gttacgtcgg
     2881 agcgcggggc gctggtggac ggggacggac ggatctgatg gatgcattgc cgctggtggc
     2941 gctgatcgcg gcgagtgcgg cggtcgcggg ggcggcgcgc aggtcgccgg tgcccgcgcc
     3001 cctgctcctg gtggcggtgg gactgatcgg ggcgtacgtg cccggggtgc ccgcctacac
     3061 cctcgacccg cacatcgtgc tgccgctggt gctgccgccg ctgctgcaca cggccgccct
     3121 ggagagttcg tacctcgatc tgcgggccaa cctgcggccg gtggcgctcc tctcggtcgg
     3181 ctacacgctg ttcgcgacgg tggcggtggg atacctcgcc taccttctcg tgcccgatct
     3241 gccgctgacg gccgcgctgg tgctcggcgc ggtgatcgcg ccgccggacg cggtcgccgc
     3301 caccgccatc gcgcgccggc tgcgcctgcc gagccgcatc accacgatcc tgcagggcga
     3361 gtccctggtg aacgacgcga ccgcgatcac cgcgtacaag gtggcgctcg cggcggccgt
     3421 cggggcgggg gccacctggg gcggcggggt caaggagttc gcgctcgcct ccatcggcgg
     3481 agtcggggtg gggctcgtcc tgatgctgcc gatccactgg ctgcgccgcc acctccacga
     3541 ggcgctgctg cagaacacat tgtcgctgct catcccgttc gtcgcgtacg cggcggccga
     3601 gcaggtcggg gcgtccggag tgctggccgt ggtggtcgtg gccctctacc tcggccaccg
     3661 gtcctggcag gtggacttcg cgacccggct ccaggaggag gccgtctgga agatggtctc
     3721 cttcctcctc gaatcggcgg tgttcgcgct gatcggactg caaatgccgg tggttctcaa
     3781 gggacttggg gagtacgggg tcggcgaggc ggtctggtac gcgatcgggg tgttcgtcct
     3841 ggtggtggcg gcccgcttcg tctgggtctt cccggccacg ttcctgccgc gcgcgctgtc
     3901 cgagaagatc cggcgccgcg agccggagac ggactggacg gccccggtga tcgtggggtg
     3961 ggccgggatg cgcggggtgg tctcgctggc catcgccttc tcgatcccgc tgacgatggc
     4021 ggacggttcc gccttcccgg cgcgcaacct ggtcctgttc ctgaccttca ccacggtcat
     4081 cggcacgctg gtcgtgcagg gcctcaccct gccgccgctg atccggctgc tcaagctgcc
     4141 cggacgggac acgcaggccg agacgctggc cgaggcgcag gcccagagcg aggcgtcccg
     4201 ggcggccgag gcgcgcctgg acgagctgct cgccgacccg cgcagcacgc tgccaccgcc
     4261 gctcgcggac cggctgcgga cggtcctgga gcggcgccgg aacgcggtgt gggagcggct
     4321 cggggcggtc aacgaggtga cgggggagtc ggcggacgcg acgtaccggc ggctgtcgcg
     4381 ggagatgatc gaggcggagc ggaaggtgtt cgtgtccctg cgggacgatc ggcgtattga
     4441 cgacgagatg atgcggacgt tgctgcgcag gctggatctg gaggaggcgg cggcctaccg
     4501 cgaccccggg acgtagcggc ctccccttgg ggctctgccc caaaccccgg gggattttgc
     4561 ccaccctccc gcccgtatgc gcggggttgg ttggttccgg gttcccctgg ggctccgccc
     4621 cagaccccga tcgcgcctca agggcgctcg tcctcaaacg ccggacgggc tgtaggcgcc
     4681 ccggcaccgg gtctttcagg ggccgacatc cgcggacggg ctgtaggtgc ccccgcgccg
     4741 ggtctttcag gggcgcgagg accggacggg ctgtaggtgc ccccgtaccg ggtctttcag
     4801 gggcgcgggg aactgcgcga ccggccgcgc acggtccgca gtcgaactcc tgccacgcgt
     4861 ctcctcaccc ccggagggtt gcgggaaggg gtggggtggg gcgagaaacc ggggtccggg
     4921 gcggagcccc ggcgcatccc ggccccggcg catcccggct ccggcggggc ctgtcacggg
     4981 cggccggtga tgactgccgt cagcgtcgtg cccggggtga acgacccctc ctgcgtcagc
     5041 gcgtgcagcg cgaacagcac cttcgccaca tacacccgct ccacccccac cccgtgccgg
     5101 tcctcgaagt cccgggcgaa cgcctccagt tcgggaggca cccgcgcgta cccgccgaag
     5161 tggaagcggt cgtccagggt ccaggtgccc cgggggccgc cgaaagcggc gcgctggagg
     5221 gcgtcgacct ccccggcgag gaagccgccc ttcaggaccg gtacgccgat cgcccgctgg
     5281 gcggggccga ggccggcggc gaggcccgca agggtgccgc cggtgccgca ggccacggcg
     5341 gcgacgtcgg tcgggccgcg cagctccgcg cccagctccg tacagccctg tgccgcaagg
     5401 gagttgctgc cgccctcggg gaccacgtac gccccggggg cgaggaggcc gaggaggccc
     5461 gccaggacct ccgggtcgga cttgcggcgg taggtcgcgc ggtccacgaa gtggagccgc
     5521 atgccgtccg cagcacatcg cgcgagcgag tcgttgagcg ggcggccggc cagttcgtcg
     5581 ccccgtacga cgccgatcgt ggggaagccg aggagccgcc ccgccgcggc cgtcgcgcgg
     5641 aggtggttgg agtaggcgcc gccgaaggtg aggacgggcc gcccggccgc ggcccgcagg
     5701 ttcggcacca gtttgcgcca cttgttgccg accagggccg ggtggatcag gtcgtcccgc
     5761 ttgagcagca gccgcacccc gtgccgcgcg aagcgctcgt ccgtcacctc ctccaggggg
     5821 gaggggaggc ggggggcgag cgcttcgggg gtcatgcacc cattgtcacg tcagtcaccc
     5881 gctgtcactt caggcgctcg tgcacgcgtt cccgcagcca gtccatcgtg aagccgcgcg
     5941 ggtcgatctt gccgacctgc cactccttgt gaccgatgac cgaacgctcg gtccagccgt
     6001 agtgacggca cacggccgcg gccgccttct cgatggcttc gagctgggcc tcgggccagg
     6061 ggtccttgcc gtcgcccagg ttctcgcact cgaagccgta gaagtgcgtg ttcccgtcgg
     6121 tgtcgttcgt cagcggctgc ggcagccgct tctcggcgat caccgcgcgc agcacgttgc
     6181 cgtcccccgc gcccgcgtgg ttggcgcggc cgttgccgac gaggtggacc gtgccgtcct
     6241 tggtgatcac cccgtggcag agcgggcccg gcagggagtc gtagccgtcg tagcagatgc
     6301 ggaccgtggc gtcggcgccg ctggtggcgg tgtggtggat gacgacgccg ttgatcgggg
     6361 cccagccgcc gtggccggcc cggttgtggg tgcgccactg gccgacctcg acgacgcgga
     6421 ggccctcggc gcgcagggcg gcgaggaatt ggtctgcgga catgggtggg gccatggccg
     6481 cctccttcca gagcggtgcg gaatatctcg taccgcttgt accccaactc ccgctatggg
     6541 gcgatctgtt cggtttgccg tgcgagctga tccggacagc ccccgcgccg tcgaagggcg
     6601 ggtcagtcct gggccagcca caggtcgggg ccgaacacct cgtagtggac gtcggccgcc
     6661 cgcacgccct tggcgaggag ctgggtgcgc accgcgcgca tgaacgggag cggcccgcag
     6721 aggtaggcgc gggtgccggg cgcgaccgga aggcgggtca ggtcgaccag gcccgtgcgg
     6781 tcggcgggat gcccgggctc ggggtcctcg taccagaagt gggccgtgga gtccgggagt
     6841 tgggcggtga gagccgcgtg gtcgtcgcgc agcgcgtgct cggcggggga gcggtcggcg
     6901 tgcaccacgg tcaccggggc gcggtggccg tcggccgcca gctgacccag catcgccacc
     6961 atcggcgtgc agccgatccc cgccgacgcg agcagcagcg gggacccgtc ggcgtcgagg
     7021 acgaggtcgc cgtacggcgc cgagacgcgc agccggtcac cctcgcgcag gtgggcgtgc
     7081 aggtggccgg aaacctcgcc gtccgggtcg ccctggacgc gcttgacggt gatcgagcgg
     7141 agctcgccgc cgggtgccga ggtcaggctg tactggcgga tctgacgtgc cccgtcgggg
     7201 agttcgacct gcacggagac gtactggccg ggcttggagg cgggggccgg ggcgccgtcc
     7261 gcggggcgca gccggaaggt ggcgcaggag gccgtctcct cggtgcggcc ggccacggtc
     7321 cactcgcgcc agacgtcccc ggcgagcacg ccctgctccg cgtagagccg ggcctcgatg
     7381 tcgatcaggg cgttcgccat cagccagtac acctcgtccc acgccgcggc gaccacggcg
     7441 gtgaccgcct cgccgagcac ctcggcgatc gcggcgaaca ggtgccggtg gacgatctcg
     7501 tactggtcgg cggtgacgcc gagcgaggcg tgcttgtggg cgatgcggtt cagcatcacg
     7561 tcggggcgct cctcggggtg gtccacgaga tgtgtcgcga acgcggctat ggagccggcg
     7621 agcgcctgct tctggaggcc ggccgcctgg ttgccccggt tgaacagatc gcgcagcagc
     7681 gcgggccggt ccgcgaagag gcgctcgtag aaccgctcgg tgatggttcc gatggccgcc
     7741 ccgacggcgg gcagggtggc gcgtacggtc acggtcgact tctcggacaa catcgactgg
     7801 ctcctcttgg tcaatatctc tggttcggga ttgactgggt tgaatctgca tctgggatgc
     7861 atattcaaga aggtgcggaa gtgccgcacg gcccggtggt cgacgggccg tcagcggctg
     7921 gtgatgccga gcaggagggg gccggtcggg gcggtcacca gatcgtccac ggtgagctcg
     7981 tcgagggact cgtagaacgc ctcctgggcg cggtgcaggg cccggcgcag acggcaggcc
     8041 gcggccagtg gacacggtgt cgcgccctcg cactccacga cgtcgcccgg gccttcgagc
     8101 tcccgcacca ggccgcccac gggaacgagg tggcccgccg cggtgaccgc gagtccgccg
     8161 ccccggccgc ggcgcgcctc gacgaggccc aggtgctgga gccgtgcgac gaccttcgcg
     8221 gtgtgggtgt acgggatgcg catcgcgtcc gccacctccc gcgtggtcgg cgggacctgg
     8281 tcggccgcgt tctcgatgac cgccaggcgc atcaggacgc gcagcgccag gtcggtgaat
     8341 ctggtgagcc gcatgcctga accgtagata acttgcatca actgtgcaaa ttaaaggcgg
     8401 gcggctgccc ggtccactgg tcttctaatc ccactcattt gagtaatggc gcggggactc
     8461 tccgtgctgg aagtgttctc cacgcagttc agcttgaaga tcgtgagagc gctcagaagg
     8521 agtcacatgt cggtcgaggc aggtcccgag aaccgcaccc agcagagtct cggcacagcc
     8581 gccgcgcgga acttggcgac caccaccaag tccgccccgc agatgcagga gatcacctcc
     8641 cgttggctgc tgcggatgct gccctgggtg caggtgcagg gcggcacgta ccgggtcaac
     8701 cgacgcctca gctactcggt gggggacggc aggatcacct tcgtccagac cggtgagcgg
     8761 gtcgcggtca tccccgccga gctgggcgag ctgcccgcgc tgcgggacta cgaggacgag
     8821 gcggcgctcg gcgagctcgc caaccggtgc gagcagcgcg agtacgccgc gggcgaggtc
     8881 atcgccaccg cgggcgacgc gaccgaccgg gtgttcctgc tcgcacacgg ccgggtcgag
     8941 aagatcggca ccggccagta cggcgacgag accgagctcg gcttcctcgc ggacggggcg
     9001 cacttcggcg aggacgcgct cgtctccggc gaagccgtct gggagtgcac ctaccgcgcc
     9061 accaccggct gcaccgtgct cgtcctgagc cgggccgacg tgctcaacct cgcggagcgc
     9121 tccgagtcgc tgcacgacca cctcgcgtcg gtcaccgggc tgcccgagca gcgcaccaac
     9181 aactacggcg aagccgcgat cgacctgtcc gccggccacg tcggtgaagc gatcatcccg
     9241 cacacctacg tcgactacga gggctcgccc cgcgagtacg aactctccgt cgcgcagacc
     9301 gtcctcaagg tccacagccg cgtggccgac ctctacaacc agccgatgaa ccagaccgag
     9361 cagcagttgc ggctcacggt cgaggcgctg cgcgagcgcc aggagtacga gctcgtcaac
     9421 aaccgggagt tcggcctcct gacgaactgc gactacgagc agcgcctcca gccgcacgac
     9481 ggcgtgcccg gccccgacga catggacgag ctgctctcgc ggcggcgcgg ctccaagctc
     9541 ttcctcgccc acccgcgcgc catcgccgcg ttcggccgcg agtgcaacaa gcggggcctg
     9601 gtgcccgagt cggtggaggt cgcgggccac cacgtgccgg cctggcgcgg ggtgccgatc
     9661 ttcccgtgca acaagatccc ggtcagcgac gcccgtacga cctcgatcat ctgcatgcgt
     9721 accggcgagg ccgagcaggg cgtgatcggg ctccagcagt ccggcatccc ggacgagatc
     9781 gagccgagcc tgtcggtccg cttcatgggc atcgacgagc aggcgatcat ctcgtacctg
     9841 gtcacggcgt actactcggc cgcgatcctg gtgcccgacg cgctcggcgt cctggagaac
     9901 gtcgaggtca gccgctggcg gtgagcctcc ggtccgggcg cgccgacccc ggcgtgcccg
     9961 gtgccgccga caactcccag gaaaggcaac ctagttggcc atgccggaag ccatggaggg
    10021 ccgcgaggcc ggtgacctcc tggagcgggc ccgtaccgtc gtcgaccccc aactgcgcgc
    10081 cagcgtcgca tcgttgcccg gctccatgcg gcgggtggcg atgtaccact tcggctggga
    10141 gcacgcggac gggaccccgg ccggcggcca gtcgggcaag gcgatacgcc ccgccctcgt
    10201 cctcgccgcg gccacggcgc tcggtgggcg gccggaggcc gcggtgcggg cggccgcggc
    10261 cgtcgaactc gtccacaact tcacgctgct gcacgacgac gtcatcgacg aggacgccac
    10321 ccggcggcac cgcccgaccg cctggaccgt cttcggcacg ccggacgcca tcatcgtcgg
    10381 cgacgccctg ttcgccctcg ccctccggct gatcgccgac gacggccatc cggcctcggg
    10441 cgcggcatcc gcccggatcg cggcctgtgt catcgaactc tgcgcgggcc agcaggccga
    10501 ctgcgccttc gagcagcgcg gcccgcagga cgtctcgctc gacgagtgca tcgccatggc
    10561 catggccaag accggcgccc tgctcggctg cgcctgcgcg ctcggcgcgc tgtatgcggg
    10621 cgcgggggac gaggaggtcg ccgcgatgga cgcgttcggc cgggaggccg ggctcgcctt
    10681 ccagctcatc gacgacctca tcggcatctg gggcgacccc ggtcgcaccg gcaagcccgc
    10741 cggagccgac ctcgccgcgc acaagaagtc gctgcccgtc gtggccgcgc tcaactcggg
    10801 caccccggcg gccgccgagc tcgccgagct gtacgggggc ccgatgggag cggaggcggt
    10861 ccgcagggcg gccgacgcgg tggaccgcgc gggcggccgc gactgggccc aggtgcacgc
    10921 cgccgaccgg atggcccggg ccgtcgacca cctctcgcgg gcggtgcccg atctcaccgc
    10981 ggcgggcgaa ctgctcgccc tggccgagtt cgtgacccgc cgtacgcgtt gatccgtcgc
    11041 cggcggccgg tctcgtgacc tgcctcgtga cctgactggc ggccggtctc ctcgcggccc
    11101 aagtggccca gtgaagccga agccgagtgg ccccaaccct gggccattcg gcttggtttg
    11161 atgggctcat gacctcccgc ctcctgccgc ccgccggccc cgcccgcggt ctcgccacgg
    11221 cccagctcgt caactccctg ggcgacggcg ccttcctggt cacctcggcg ctgtacttca
    11281 gccgcgtcgt cggcctgccg gccacccgca tcggtctcgg cctgaccctc gcctgggcgg
    11341 tcggcgcgct cgccggggtg ccgctcgggc agctggccga ccggcgcggc ccgcggaccg
    11401 tcgccgtcct gctcgccgcc gccacgggcg cctcggtcgc gtccttcctg ttcgtccgcg
    11461 gcttcctccc cttcgtcctt gccgcctgct gctacgcgac cgcacagacc gggctctccg
    11521 ccgcccgcca ggcgctcctg tccgcgctcg tcgaccgcgg ggaccgcacc agggtcctgg
    11581 cgcacctcca gtccacgctg aatgccgggc tcgccgtcgg cgcggcgttc ggcggggtcg
    11641 ccctgcacta cggcacccgc accgcctacc tcgccgtgtt cgccctggac gcggtggcct
    11701 tcctgttctg cgcgctcgcc ctgatgcggc tgccccacgt gccgccgagg cccgtcgtgc
    11761 ccggcggggg gccgcggttc gccgtgctgc gcgaccgccc gtacgccgtg atcaccttcc
    11821 tgaacaccct gctcctgctg cggatgccac tgatcagcct cgccgtcccg ctgtggacgg
    11881 tcacccgcac cgatgccccg ggctggctgg tgtcggcgct gctggtgctc aacaccggtg
    11941 ccgtgatgct cttccaggtc cgtaccgcct ccgccgtgcg tgatctgccc agcgcccggc
    12001 ggaccgtggc gcgcggcggg gtgctgatgc tggcctcctg cgcggcgttc gcgctcagcg
    12061 ccgccggtgc gtcgccctgg gccgccgtgg gtgtgctgct cgtggcgggc gggcttcagg
    12121 tggcgggcga gatgatgcag tccgcgggcg cctggcagat cggcttcgac ctcgcgccag
    12181 ccgatcaaca gggccagtac cagggcttct tcggcatggg cgtaccgctg gccaggatgc
    12241 tcgggcccct gctgctcacc gcgctcgtca tcgactgggg cgtgcccggc tggctggtgc
    12301 tcggcgcgct gttcctcggt gccggcctcg cgctcgggcc cgccgtccgc tgggccgagc
    12361 ggtccaactc cgcgcttgtg gcggctggtt gaagcagtca tggcgggcgg gagcggcgga
    12421 gacgggggcg gacgtctcga agcgcgcaag gaagcggtaa cacccatttc ggtcaccccc
    12481 tgtgacgaat ggcagggtgc gccgctaatc tccgcccatg acaccacagt catgggcggg
    12541 ttggtatcga gaccgcctag gatcagaagc gctgacgatc accacggacg ggacgcaact
    12601 gcggacccgg atcagggggg tcgacttcgc cggagcgagc ttcgactcgc tcggcccggt
    12661 tccggggata ccgacggaga gcggtgcgtt cgcgctcgac gacgggaacc tccgtgactt
    12721 cgtactcgaa tgggacatgc ccgtgcccat cgcctcggac gacggcgccg tccaggaggc
    12781 caccctcagc tgcctgctct ccctgaaacc gccggagccc gacctcgggg tcgccctgca
    12841 cttcggggga gcggtgtacg ccagcgggcg ggccgaagtc gacttcggct cggtgctcgc
    12901 cgacatccgg cgccaactcc cgtccggttc aagcctccag ccgtccgctc tggacgccat
    12961 atagctcaac gccccatcct tctctcccgc ggccgccgcg caccggggag tccgtccgac
    13021 tccccggtgc gcggcggccg ctctgtatcc ggagctgaac agggcgcgcg atggggcgag
    13081 ttggggggtt gccctaagcg tgcattgttc tactaccatg cgaacaagga ggtttcgatg
    13141 atccgtgtcc gccaccgcct gaccgctgtc gccgcgctcc cgttcctgct cgccctggcc
    13201 gtcgacctga cgctgtacgt gcttctccac gaccggctgc ccgatccgtt ggccagtcac
    13261 ttcaccggga acggccgctc cgacggcacg cagagccgtg gctccgcccc ggtcttcgcg
    13321 tgcgtgctgc acctcggcct cggcgccctg tgggccggca tggcggccgt cggaggccct
    13381 gccgtacgcc ggctccggtg gctgatcgcc gccgggtacg cgacggccgg gttcgtgggc
    13441 tacctcctgg ccgccacgct gctcgccaac gcggacgcga ccgacccggc gcgggtgcgg
    13501 ctgccgctgt ggcagatcgc cgtcggcgcg ggcgtcgcgg tactcgcggc ggcactcggg
    13561 cggctgttgc tgatggccct gccgacgccg ccccccgagc cctcctcgcg tccggacgcc
    13621 gaccggaccc cgcggctcga cctcgccgag ggcgaggtgg cggggtggat gcggcgggcg
    13681 ccctcgcgcg tgctgctcgt ctgcggggcc ctgctgttcg tcgccgcggg cgccctgctg
    13741 ttcgccctcg gcccgagcca tggggtgggc gcgctcttcg gtgccgtggt gtgcctcgtc
    13801 ttctcctgcc cgtacgtcac cgtcgaccgg cggggcctga ccgcgcggcc caccgcgctg
    13861 ccctggccgc gcatcagaat cccgctgtcc gacgtggacc gggcggtcag ccgtgacatc
    13921 aaggtcctcg cggagtacgg gggctggggc tatcggacgc gtgcgggcag gtcgggcctc
    13981 atgctgcgct ccggcgaggc gatcgtcata cggcggtcgg acgggcggga gttcgccgtg
    14041 acggtggacg acgcggggac ggccgccgcc ctcctgaaca cactggcccg gcgcgcggag
    14101 gcgagggact gatgctcttc cgtgtggacc ccgcctcgcc cagaccgctc ggcgaccaga
    14161 tcgcggcctc ggtacgcggg gcgatcgccg acggcaaggt ggccccgggc gaacgcctcc
    14221 cgcccgcccg ctccctcgcg gacctgctcg gggtcaacgt ccatacggtg ctgagggggt
    14281 accagcggct gcgcgacgag ggcctgatcg agctgcgccg gggccgcggc gcggtcgtcg
    14341 tggacgacac ccgggcgcgg ggccgggcgg agctgatgct cagggtgcgt gaactggtcg
    14401 atcaggcacg ggagttggga ctgaccgagg acgaggtcgt ggggctggtg cggcgcggcc
    14461 tcgcgtgacc gtgccggctc gcggaggcgg cccgtgttcc cgggcccgtc agtacgtctg
    14521 gagttccacc aggtttccgg ccgggtccag gaggtgcgcg gcgcgcattc ccgggcccca
    14581 ctccggcagg tcccgcacgg gcacggccac ggtgccgcca gccttcgcgc acagcgagac
    14641 cgcggcgtcg agggcgtcgc gcgtggccac gtggatcacc agggaagcgc ccccgcccgg
    14701 catccggtcc tcgccgagca cggcggccat cgcggagcgg gtgaacagcg cgagggcggt
    14761 gcgcccgtct ggggcatccc aactggcgta tccggacgcg gagttgccgc gggcgagggt
    14821 gcagccggtg aggtccggca ggacggcgtc gtagaagcgg aacgccggtt cgtacgggtc
    14881 gacgagaagc cgcgggtacg gaggctccag agggtccatg ccctcgaacc taacccggaa
    14941 gacggccctc cgcggtgtgc cagtggtcac gcgtcccgac ccggcccgga gccggagcgg
    15001 gcccgttccg gggcgccggc tcgggcgggc cgggcgtacc gctcggcgat cagccgggcg
    15061 caggccatgg actccgcacc ggccgagtcc acctcgatgt cgtaccgcac ccccgcgtgc
    15121 acggactcgg cctggccccg ggccatgccg gggacgcggt cgccacgggc ggtctcgcgg
    15181 cccgcggccg tgtcggggtc gcagcgcacc ccgacccaga gcacgtcgag cccgtcgagg
    15241 gcctgctgcc agcgcttctg ggcgtcggcg ccgtcgagga agacctcgtc gagcaccacg
    15301 tgggcgccgg cccgcaccat cgcggccacc ccgcgcgccc aggcgtccga gagccgacgg
    15361 tagtcggggc ccacggtcac cgtgccgtcc gccccgatct ccaggccgcc ctcgccgcgg
    15421 agcgaggcgg gcatggccgc gtccaccgag tcgacgccga aggcgagcca ggcgccgggc
    15481 agcacggcct gcaggcaccg gacgatcccg gacttgccgg aactggaccc gccgttgagc
    15541 acgatcacct ggcaccgggg cgtacgcgtc tgatccgtca cgcgcgccac ggtaggcgcc
    15601 ggccccggcc cggccaagcg aattccgcgc gcgataacct gccccgatgc ggcgcatcct
    15661 cgtggtcggc agtaccggag ccggcaagtc caccctggcg cacgagctgg gcgagcggct
    15721 cggggtgccg taccacgagc tggacgcctt gcacttcacg ggcccgggct gggcgcagga
    15781 cccggacttc gcggcccggg tggccgagat cgcggccacc ccggcgtggg tcctcgactc
    15841 gtacggcacc cccgatgtcc gccccctgct gtgggagcgc gccgacacgg tggtctggct
    15901 ggactacccc cggcacgtcg tgatgccccg cgtgctgcgc cgctcgctgc gccggaccgt
    15961 actgcgcgag cggatcttca acggcaaccg cgagacgctg acggagtggt tccgcggcga
    16021 ccacccggcc cgttgggcct ggtcccagta cgcgccccgc agagcggccc tgacggccct
    16081 caccaccgac cccgccctcg ccccgctgca caccctgcgc ttcacggctc cgcgcgaggc
    16141 acggcgctgg ctgcggacga tcgaggccgg ccgcggcgaa cgccggaagg gcccggccgg
    16201 gtaaccccgg ccgggccctt ctcgattcgc cggtgctcgg ccgcccgaag gcgtccggcc
    16261 tgcgaactcg gcctggatca ggccttcttg gtctcccaga agatgcggtc gatctcggcg
    16321 atgaggtcga gcgccttctg tccggtcgcc gggtcggtcg acgccttggc ggccgagagg
    16381 gccttcaggg tgtcgttcac cagctggtgg agctccgggt acttctcgaa gtgcggcggc
    16441 ttgaagtagt cgctccacag caccgacacg tggtgcttgg cgagctccgc gcgctgctcc
    16501 ttgatgacca cggcacgggc acggaagtgc gcgtcctcgt tggcctggaa cttttcctgc
    16561 acggccttga ccgactccgc ctcgatgcgg gcctgggccg ggtcgtacac accgcagggc
    16621 aggtcgcagt gcgcgctgac cttcaccttg ggggcaaaca ggcgggaaag cattgagctg
    16681 tccttcctcg tgatcgtctt ctcaggtggg acattactcg gtgagaggcg gtatttcgcg
    16741 ggtgccccca tgggcttagg tcaaaagtcc aggggcaccc cgggactcgt ggcggaacgt
    16801 accgtgggat cggcggcggg gtgccggtgg ccgggaggtg ggtgaggtat gacggatgag
    16861 gggcgggagc cgagggtgcc gttggggatc gcggaggtcc tcgggacctc gatggttccc
    16921 acgctgctgc acggggatca gctgctcgtg cactacggcg cggagctgcg gatcggcgac
    16981 gtggccgtgc tgcggcaccc gctgcagcag gatctgctca tcgtcaagcg gctcatggag
    17041 ctgcgcgaga gcgggtggtg ggtgctcggc gacaacaccg acgacgaggt cgtggacagc
    17101 cgggccttcg gtgcggtgcc ggtcgacctc gtgctcggac gcgtgcgcgg acgcttccgg
    17161 ccgatggcgg cggggcgccg gcgcacgatc ggctacctgg cgtcctgggc ggtctcctcg
    17221 gtgagacccg tgctgtcgga ccgctcggtc tccagacgct tgcgcgcccg gtaggcggcc
    17281 acgttggccc gggtcgcgca ccggtccgag cagtagcggc gcgagcggtt ggtcgaggtg
    17341 tccaggtagg cgttgcggca gggcgccgcc tggcacaggc cgagccggtc gaccccgtac
    17401 tccgtgaggt ggaaggcgag ccccatggag gcgatcgcgg cgtagcccgc cgtcgcgttc
    17461 gaggggtggt cggcgaggtg catgtgccac agcgggcggc cgtcgtcgtc gcggtgctca
    17521 tggcccgaca cctgggggct gaccgggaat tcgagcagca gcgagttcag caggtccacc
    17581 gcctggacct cctcgccgcg gtccgcggcc tcgaagaccg cccgcagccg ggcccgtacc
    17641 gaacggaagc gcgtcacgtc cgcgtccgtc gcccggcggg ccgccgactg gttcccgccg
    17701 aacaggtccc ggaccgcctc gaccgaggtc agggcgtcct tgttgcgggc cggctcctcg
    17761 gtgttgacca ggcgcacggc gtagtccgag taataggcca gttccacttg tagtccttac
    17821 ggcggcggtc tatggtctga gctgtccaca agtaacggct ggataccctt tgagggtatt
    17881 acagactggc tgtgtaggag ggatcgcggt gtcggagact gtcactgggg ccggaacggg
    17941 caccgactgg cggggctggc aggacagctg ggaccggcag caggagtggt acatgccgga
    18001 ccgcgaggag cgcttccggg tcatgctcga catggtcgag gcctgcgtcg gtcccgcgcc
    18061 gcgcgtgctc gacctcgcgt gcggtacggg gagtattacg gaccggctcc tccggaggtt
    18121 cccggacgcg gtcagtaccg gggtggatct cgaccccgcg ctcctcgcca tcgccgaggg
    18181 caccttcgcg ggggacgagc gggtcacctt cgtcgccgcc gacctcaagg acccgcactg
    18241 ggtccagtcg ctcccgtacg actcctacga cgccgtcctc accgcgaccg ccctgcactg
    18301 gctgcacgcg gagccgctcg ccgcgctcta cgggcaggtc gccgggctcg tccgggacgg
    18361 gggcgtgttc atgaacgccg accacatgat cgatcccgcg accccgcgca tcaacgccgc
    18421 cgaacgcgcc caccggcacg ccgggatgga ccgtgccaag gccggcggcg ccctcgactg
    18481 ggcgcagtgg tgggagctcg ccgccgcgga cccggccctc gccgggccga ccgccaagcg
    18541 gtacgagatc tacggcgagc acgccgacgg cgacatgccc gccgcgggct ggcacgccga
    18601 gaccctgcgc gcggccggtt tcgccgaggc ccgcccggtc tgggcatcgc cttcggacac
    18661 cctgctgctc gccctgaagt agccgacggg aaaggggggt tgcgggcgcc ggcccgtaac
    18721 cccccttgtc catgcggtcc ttacagcacc ttcgacagga acgacttcgt ccggtcgtgc
    18781 tgagggttcg tcaggacatc gcgcggatgg cccgcttcga cgaccacgcc gtcgtccatg
    18841 aagaccagcg aatcgccgac ctcgcgcgcg aagcccatct cgtgggtgac cacgatcatc
    18901 gtcatgccgt cctcggcgag accgcgcatg acgtccagga catcgcccac cagctcgggg
    18961 tcgagcgccg acgtcggctc gtcgaagagc atcagcttcg ggtccatcgc cagcgcgcgg
    19021 gcgatcgcca cgcgctgctg ctggccgccg gagagctgcg acgggtagtt gcccgccttg
    19081 tcggcgaggc ccacccggtc gagcagcttc agggcccgct cgcgggccac cgccttcggc
    19141 tcgcgcttga cctggaccgg cgcctccatg acgttctcga cggccgtcat gtgcgggaac
    19201 agattgaagc gctggaagac catgccgatg tcccggcgct tcagggcgac ttcgctgtcc
    19261 ttcagctcgt agagcttgtc gcccttctga cggtagccga ccagctcgcc gtccacgtag
    19321 aggcgcccgg cgttgatctg ctccaggtgg ttgatgcacc gcaggaacgt cgacttgccg
    19381 gagccggagg ggccgatcag gcagaacacc tcgccctcgg ccacctccag gtcgatgccc
    19441 ttgaggatgt gggcggggcc gaacgacttg tggacgccct cggccttgac catcggttgt
    19501 gcagtcatgg ggtcaccgcc gccagtggga gagggagagc aggttcgact tgatgcgctg
    19561 cagcggtgtg ggcggcaggg agcgcagcga accgcgggcg aaacgacgct ccaggtagta
    19621 ctggccgacg ctgaacacac tggtcagggc caggtaccag atcgacgcga cgaagagcat
    19681 ctccatcacc gcgaacgagg tcgccgcgac gtcctgggcg ctgcgcagca gatcctggta
    19741 ctggacggcg acgaccaggg acgaggtctt cagcatgttg atgaactcgt tgcccgtcgg
    19801 cgggatgatc acccgcatcg actgggggag caccacgcgg cgcatggtct gcatctgggt
    19861 catgccgagc gcgtgcgagg cctcggtctg accctcgtcc accgactgga tgccggcccg
    19921 gacgatctcc gccatgtacg cgccctcgtt gaggccgagg ccgagcaggg cggcgaggaa
    19981 cggagtcatg accgcggtca tgtagtcctt gtagaacccg aggttgagga tcgggaagat
    20041 cagcgccagg ttgaaccaga tcaacagctg tacgtagacc ggggtgccgc ggaagaacca
    20101 gatgtacagc caggcgaccg aactggtcac cgggttcttc gagagtcgca tcacggcgaa
    20161 cagcacgccg aggaccagac ccacggccat ggagaccacg ctgatcagaa tggtgtgcca
    20221 gaggccggtc aggatgctgc cgtcgaacag cttgtccgtc acggtcgccc agcggacgtt
    20281 gccctgggcg aacgcgtaga ccagcgcgcc gagcacggcg acgaccacta cggcgctgac
    20341 ccagcggccg tagtggcgca ccgggatggc gcggatgatg tccggcggga cctgctccgg
    20401 ggcggcgtcc gccggccccg gagtcttgtc gagcttgtca gtcacagcga ctgcccttca
    20461 gtggtgcgcg ggtcaggagc cgccgttgat ggctgccttg gtgacggcgc cctgcgcgcc
    20521 gccccacttg tcgatggccg tcttgtacga gccgtccttg atgatcgcgt cgagggcctc
    20581 ggagagggcg tcgcgcagct gggtgttctt cttgtccacc gcgatgccga acgggcccgc
    20641 gtccgagggg ttggccaccg actcgaagtc ggcgccgccg cccgcggtct tcgcgatgta
    20701 cgcggcgacg ggggagtcgt tcaggtcggc cacggcgcca ccggccttga cgcgggtctg
    20761 cgcctcggcg tcgctggaga aggcctcgac ggtgagcttg cccttgccgt ccttcgcgca
    20821 cttggcgacg aggtccttgg cggcctgctc gtaggtggtg ccgcgctgca cggcgatcgt
    20881 cttgccgcac aggtcgtcgg tggacttgat gccctccggg ttgcccttct tgaccaggat
    20941 gccggtgctg gccgtgtagt agtcgacgaa gtcgacgccc gtaccggtct tcttgccgct
    21001 gtcgtcaagg ccctgctggc gcttcttggt gt
//
