LOCUS       NZ_BMUU01000015        21257 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence15, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000015
VERSION     NZ_BMUU01000015.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 192596)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 117947
            Orig. end                         :: 139204
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21257
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="2"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21257
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21257
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11257](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11257)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(502..511)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     gene            complement(765..1715)
                     /db_xref="GeneID:96294489"
                     /locus_tag="IE233_RS32445"
                     /old_locus_tag="GCM10010326_66120"
     CDS             complement(765..1715)
                     /codon_start=1
                     /db_xref="GeneID:96294489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131132.1"
                     /locus_tag="IE233_RS32445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66120"
                     /product="RNA-binding protein"
                     /protein_id="WP_190029026.1"
                     /transl_table=11
                     /translation="MPPSFVHRITKYDPADRDEHGHYTGAEEAVSDHGPVEAAYLAAIA
                     AFAEASGIDRLEIREPAVTGLAHFGVKPSDGRHGLGGLFPPDLSGYHDGAEVSLPVALE
                     LVRGMLRDQGAWCRLESGDAFTVHVGWDQYVYVGSDQLCANAVARTRELGLFPEPMATS
                     PYAAELQEPDVTEAAGDGFWARVHTVLASRKAVLLREGYVRNAVRFHRLTPENLDAVRT
                     GLSPRALLTVWPDLNPDVGAVLATLLEEGSAEFVWEAQDGTIRHAVVDDTEYQELATLV
                     AGARAACALPVYLDERHPLLCATLPDNDGVPRARW"
     gene            complement(1744..2610)
                     /db_xref="GeneID:96294490"
                     /locus_tag="IE233_RS32450"
                     /old_locus_tag="GCM10010326_66130"
     CDS             complement(1744..2610)
                     /codon_start=1
                     /db_xref="GeneID:96294490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139584.1"
                     /locus_tag="IE233_RS32450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66130"
                     /product="hypothetical protein"
                     /protein_id="WP_190029027.1"
                     /transl_table=11
                     /translation="MQKTVLVPYAHLPHAHHDRHVLTSTVDVFGTAHWLLADHVPQAGD
                     AVRPFDALVASVDPDGHAELTELSAVRARWPHLDRLPDGRFVVAASRARRYEDANQVQV
                     FDAHGRETSAFSVGDAIEHLLVDEASRIWVGHFDENPVGIRCWSATGRLTWTSDDAGIP
                     GLFDCYALNVSGTTAWACPYTDFPLVDIRPDRSHRPVRVWANRVRGAKAVAVHGERVTF
                     YGGYGEERDRLAHGEIMETSVGPTDVGLLTLPDGSVPGRRRVVGRGSRIYVQAEPFTTW
                     GVFDLSS"
     gene            complement(2861..3955)
                     /db_xref="GeneID:96294491"
                     /locus_tag="IE233_RS32455"
                     /old_locus_tag="GCM10010326_66150"
     CDS             complement(2861..3955)
                     /codon_start=1
                     /db_xref="GeneID:96294491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319622.1"
                     /locus_tag="IE233_RS32455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66150"
                     /product="barstar family protein"
                     /protein_id="WP_161247672.1"
                     /transl_table=11
                     /translation="MISVVHEDEKARGSASYALTETDHGHVWGVCAEVEGLFGECRRGT
                     YELFGWVPEVSSVSGWVGSRVWLVPEDDACDVWLLEDAESSGQVGTDSRLLTGLDDYEG
                     PPEGYRGRVRVHDGHRWLGSCREFIRIMPPEQVPAPIVLRGLAPSDRLSAALAKGTRRA
                     LDLEEAALEIRDVQGEMLTDRLLRTTISAWRPSSCGVGLIDLELDGCRYTPVPEYARSI
                     WERWLAGPPAAVNTWAGLDTRRRGAWHDLVRDRGCRRSHRDRPAGHAYELDGRYVTDEP
                     ALYLALGEAVNGPGGYFGGCLTALDDCLRGTFGYTAPATLLWRDAATAREHLSHALTPD
                     GQPYNLFTTILETLAGGGVDVTLA"
     misc_feature    4121..4134
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.87"
                     /tool="antismash"
     gene            4611..4862
                     /db_xref="GeneID:96294492"
                     /locus_tag="IE233_RS32460"
                     /old_locus_tag="GCM10010326_66160"
     CDS             4611..4862
                     /codon_start=1
                     /db_xref="GeneID:96294492"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS32460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_66160"
                     /product="hypothetical protein"
                     /protein_id="WP_190029028.1"
                     /transl_table=11
                     /translation="MSEARALEDAPLRRRDPREAQITWLEAAITQLREQPTQSEQTVEE
                     LTDFCGQAVARLAAQHEEVVRLREATAEESKVRRLPTP"
     gene            complement(4928..5449)
                     /db_xref="GeneID:96294493"
                     /locus_tag="IE233_RS32465"
                     /old_locus_tag="GCM10010326_66170"
     CDS             complement(4928..5449)
                     /codon_start=1
                     /db_xref="GeneID:96294493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047898.1"
                     /locus_tag="IE233_RS32465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66170"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_190029029.1"
                     /transl_table=11
                     /translation="MSELVEYVDQHDRVLGVVDRDEAVRENWSHRIATTICRDREGRIL
                     VLRRAETMSRFPGYYDVMVGGAVNVGETYEQAAVRELTEELGVRAPVRFLFKFLCRQGI
                     SPVWFGVHEAVVSEALGPAPGEIGWQDWMTVDELREVADEWAFVPGGREALRRYSECGF
                     GSGAGRQAAE"
     misc_feature    complement(5507..5524)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     gene            complement(5917..6378)
                     /db_xref="GeneID:96294494"
                     /locus_tag="IE233_RS32470"
                     /old_locus_tag="GCM10010326_66180"
     CDS             complement(5917..6378)
                     /codon_start=1
                     /db_xref="GeneID:96294494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019066788.1"
                     /locus_tag="IE233_RS32470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66180"
                     /product="hypothetical protein"
                     /protein_id="WP_190029030.1"
                     /transl_table=11
                     /translation="MSDNYLTVIPTDPYWQPGKDAADRAAVVLSGMLSDDDARRGLDAK
                     WHDSVEVVHCCANLKRISCPRCGTELTPLWWGDAVSQCYDGGFSTLKVTVPCCDAETSL
                     NELVYDWPMGFARFRIEILYPNRAWLTNGELASLAGALGHPVRQILIHI"
     gene            complement(6833..7423)
                     /db_xref="GeneID:96294495"
                     /locus_tag="IE233_RS32475"
                     /old_locus_tag="GCM10010326_66190"
     CDS             complement(6833..7423)
                     /codon_start=1
                     /db_xref="GeneID:96294495"
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237296.1"
                     /locus_tag="IE233_RS32475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66190"
                     /product="transposase"
                     /protein_id="WP_190029031.1"
                     /transl_table=11
                     /translation="MNTRAWIVFLDESGVSLLPQVRRTYAPRGRTPLLRHRLNWKRASM
                     AGALGYHSTDPERGARPCFHLKPGSYDTPGLTEVLEQMKVFYRGENVVLVWDGLSAHWS
                     RAMRAWVAEQDWLTLERLPAYAPELNPVELLWSSIKKRELANLAGDHLADVADAAEQGI
                     HRINTNPQLPWSFLTHTGLTIRPPHPPNLRKNQ"
     misc_feature    complement(6848..6850)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(7058..7060)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7420..7935)
                     /db_xref="GeneID:96294496"
                     /locus_tag="IE233_RS32480"
                     /old_locus_tag="GCM10010326_66200"
     CDS             complement(7420..7935)
                     /codon_start=1
                     /db_xref="GeneID:96294496"
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024954.5"
                     /locus_tag="IE233_RS32480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66200"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_267907215.1"
                     /transl_table=11
                     /translation="MAYQPSPLAAGSPLPPLSRPQLAEARRVRAVELFEEGVSNVEVAR
                     AVGVCAESVRRWRRVWEKDGALALRRRASTGRPPKLDDSQVEAVRTALEQGARAHGFEA
                     DLWTLERVGEVVARVTGVVLSRASVWRLLTGRLGWSLQRPERRAVERDESEIARWVAHE
                     WPQIKKGR"
     misc_feature    complement(7735..7737)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7975..7988
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.3"
                     /tool="antismash"
     misc_feature    complement(7975..7989)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.07"
                     /tool="antismash"
     misc_feature    complement(7982..7991)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            complement(8150..8290)
                     /db_xref="GeneID:96294497"
                     /locus_tag="IE233_RS32485"
     CDS             complement(8150..8290)
                     /codon_start=1
                     /db_xref="GeneID:96294497"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS32485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_190029033.1"
                     /transl_table=11
                     /translation="MTAQPELSGVDLARQAVPAAQETAKRNGEGEVAEAARRHDRAERR
                     A"
     gene            complement(8655..10028)
                     /db_xref="GeneID:96294498"
                     /locus_tag="IE233_RS32490"
                     /old_locus_tag="GCM10010326_66220"
     CDS             complement(8655..10028)
                     /NRPS_PKS="Domain: Beta_elim_lyase (41-419). E-value:
                     5.1e-76. Score: 247.6. Matches aSDomain:
                     nrpspksdomains_IE233_RS32490_Beta_elim_lyase.1"
                     /codon_start=1
                     /db_xref="GeneID:96294498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552727.1"
                     /locus_tag="IE233_RS32490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66220"
                     /product="tryptophanase"
                     /protein_id="WP_190029034.1"
                     /transl_table=11
                     /translation="MEPYRIKVVEPLAFTTREEREAALKRVAYNPFELRADEVTIDLLS
                     DSGTGAISADQLAAGMQGDESYAGSRSFYRWHEVVSELTGYPHILPAHQGRAAERILFS
                     SLLRPGTSVLSNTHFDTTRANVELTGCTAYDLPCAEAKDLDSDFPFKGNIDLIALEQAL
                     ENADQTPVAAVLMTITNNGGGGQPVSMDNLHRTAELCRRHNVPMILDAARFAENAWLVT
                     QREPGYAHRTPRQVAEEAFRLADGCVMSAKKDGIVHIGGFIGLKDAELAERCGGLLIAT
                     EGFTTYGGLSGRDLDMMARGLLEVTEPAYLAERADIAGYLAARIREAGVDIVEPAGLHA
                     LYVNAGRLLPHIPPHQYPGTALVCELYLRGGIRSAELGSLYLGEEDEHGNPVKTAPYEL
                     VRLALPRRVYTRSHYDHVAATLADIAKNPESVHGYRVTSQSPILRHFSIKLEPVKSGD"
     aSDomain        complement(8772..9905)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS32490_Beta_elim_lyase.1"
                     /evalue="5.10E-76"
                     /label="IE233_RS32490_Beta_elim_lyase.1"
                     /locus_tag="IE233_RS32490"
                     /protein_end="419"
                     /protein_start="41"
                     /score="247.6"
                     /tool="antismash"
                     /translation="DLLSDSGTGAISADQLAAGMQGDESYAGSRSFYRWHEVVSELTGY
                     PHILPAHQGRAAERILFSSLLRPGTSVLSNTHFDTTRANVELTGCTAYDLPCAEAKDLD
                     SDFPFKGNIDLIALEQALENADQTPVAAVLMTITNNGGGGQPVSMDNLHRTAELCRRHN
                     VPMILDAARFAENAWLVTQREPGYAHRTPRQVAEEAFRLADGCVMSAKKDGIVHIGGFI
                     GLKDAELAERCGGLLIATEGFTTYGGLSGRDLDMMARGLLEVTEPAYLAERADIAGYLA
                     ARIREAGVDIVEPAGLHALYVNAGRLLPHIPPHQYPGTALVCELYLRGGIRSAELGSLY
                     LGEEDEHGNPVKTAPYELVRLALPRRVYTRSHYDHVAA"
     gene            complement(10001..11257)
                     /db_xref="GeneID:96294499"
                     /locus_tag="IE233_RS32495"
                     /old_locus_tag="GCM10010326_66230"
     CDS             complement(10001..11257)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294499"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552726.1"
                     /locus_tag="IE233_RS32495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66230"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_190029035.1"
                     /sec_met_domain="indole_PTase (E-value: 1.1e-122, bitscore:
                     403.0, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFRPGPGIPATSPGETTLGHHVLSQLRRLGATVGLSEADTELYG
                     RVVVDSLAGAAHRPLSLPPASPAFLSDDHTPVEFSLASTPDAAPALRVLVEPGWAHGDM
                     ADNGRAGLAVIRAMGARWGFDTDQLDALADLFFPTAAQGPLALWYALDLRAGGVPGVKV
                     YLNPSASGPENAARTVHEALRRLGYGQAFERLPSAAGYPFLALDLGAWASPRVKVYVRH
                     PRISADDACALSRTSGATEADVRYFFHAAAGSLAPSERGGNDPLRLVRRPALTCHSFTG
                     GDSDPSGFTLHIPVRDYVRDDDEALARATALLTRAGMDPTVLNRSLGALTQRSLADGVG
                     LIAYLALVYERNRPPRLTAYLSSEAYRVRKPQDQYPRGTWMPAQRTQSVLDLGHQAAGH
                     VSPHTAQKEVTWSPTASRS"
     gene            complement(11610..12956)
                     /db_xref="GeneID:96294500"
                     /locus_tag="IE233_RS32500"
                     /old_locus_tag="GCM10010326_66240"
     CDS             complement(11610..12956)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294500"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552725.1"
                     /locus_tag="IE233_RS32500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66240"
                     /product="cytochrome P450"
                     /protein_id="WP_190029036.1"
                     /transl_table=11
                     /translation="MTTPSVPPPGCPAHGSGERIPLDSAEFAANPHAYYRYMRELGPTA
                     AVTIAPGVEATLVTDYNAALELLQDSTTFRKDSRRWRALAEGCIRPDSPVLPLLAYRPN
                     AMFTDGAEHVRLRQAITDSFARVSNKRLSRIVSQAAQFLINQFSARGSADLLRDYAQQL
                     PLYVFNELFGCPPEIGDRVLFGISGMFDGVNAEAASQVLLGAVGELVALKRAQPGEDVT
                     SYLMQHQAQLNDEELAHTLVLLLGAGGEPEGNLIGNAFYTMLTNEEFARLGQFDKAVDD
                     TLWRNAPMSNYAPHYPVVDTDVAGDKVRAGDLVLVSFGAANTALADRGADTRGHLAWSA
                     GPHACPSKEPARLIALTGLETLFNALPDVELAVPADSLAWRPGPFNRALASLPVRFSAV
                     TPRAAAAPEATMAPRYRAAPVAAASTPAAPQPVGKAGRWSSFMKWLTGQ"
     gene            complement(12953..13558)
                     /db_xref="GeneID:96294501"
                     /locus_tag="IE233_RS32505"
                     /old_locus_tag="GCM10010326_66250"
     CDS             complement(12953..13558)
                     /codon_start=1
                     /db_xref="GeneID:96294501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005331.1"
                     /locus_tag="IE233_RS32505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66250"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_190029037.1"
                     /transl_table=11
                     /translation="MASRLSLSEDAYVPSGAQQTAVKILIVGHFAVGKTTLIGSLSEIT
                     PLSTEERMTTLSERVDDLKGVQGKTTTTVALDFGRLTLSERVVLYLFGSPGQQRFVSLW
                     DDTARGALGALVLVDPERLADSFDVMDLVESYGLDFAVAINHFDGSTFHTPEEVREALD
                     LLPDTPVVTIDARDEKSSVDALITLVRYLHERADLEHA"
     gene            complement(13533..13922)
                     /db_xref="GeneID:96294502"
                     /locus_tag="IE233_RS32510"
                     /old_locus_tag="GCM10010326_66260"
     CDS             complement(13533..13922)
                     /codon_start=1
                     /db_xref="GeneID:96294502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552723.1"
                     /locus_tag="IE233_RS32510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66260"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_190029038.1"
                     /transl_table=11
                     /translation="MTEPGRPETEFVSEAGELVRPYVITRGRDLPDEGEFALITLVTAA
                     TDEQQRPQRLSPEEQQILEMCSSGYLSIAEIAAHSQLPLGVVKVLLSSLAEGGYLVVRA
                     PVPSARPTNKALLKEVLDGLKALTV"
     misc_feature    complement(13869..13871)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13919..14317)
                     /db_xref="GeneID:96294503"
                     /locus_tag="IE233_RS32515"
                     /old_locus_tag="GCM10010326_66270"
     CDS             complement(13919..14317)
                     /codon_start=1
                     /db_xref="GeneID:96294503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552722.1"
                     /locus_tag="IE233_RS32515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66270"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_190029039.1"
                     /transl_table=11
                     /translation="MSDDLSWMLEDALQIPHALHAVLISADGLQMSRTAEIDRGDADKV
                     AAAVSGLQSLSRAVGFFCGEHGANWRQTLIEFDGGWVFLNAAGGGSYLAVAASAEVDMQ
                     DITYRMQRLVSRLGKAMSTGLRGDTVTS"
     gene            complement(14314..15513)
                     /db_xref="GeneID:96294504"
                     /locus_tag="IE233_RS32520"
                     /old_locus_tag="GCM10010326_66280"
     CDS             complement(14314..15513)
                     /codon_start=1
                     /db_xref="GeneID:96294504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005328.1"
                     /locus_tag="IE233_RS32520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66280"
                     /product="ATP-binding protein"
                     /protein_id="WP_229893002.1"
                     /transl_table=11
                     /translation="MTNFWQDPTVWALVVGVAVAATVIARQRKKIKALRRQEQGLQGEL
                     TASQGRAADLESTVTELRSGYDEVVRQAKEEAEEATNTVLKSAMRTLQGLAAEQQRAIS
                     GLQKKYGDSAVLRDMLDIDHMNSQFNRRAQSIAVLCGGWLGRQREAASVYDVIRGAQGR
                     VRHYQRIEIASRVDFAVTSRAVEPIALTVAELLDNATSYSEPSTMVEVEVRTVPRGICI
                     VIDDAGVGMSEEERTNATALLSSGSAVSVSELGNPPAFGFAVIGALCARFGFTVAIDST
                     SPYGGVRAVVMVPKELLTEMPEPKTPTTTQEVNAIAASRGSASAATEGGLPRRRNKRGM
                     ALVPDGGRTSDEAPPARSAEARVAAIGAFQRGTLSGRGAGVPAAEGDTTADSHEGFDAP
                     "
     misc_feature    15717..15730
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.47"
                     /tool="antismash"
     misc_feature    15725..15734
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     gene            15809..>16523
                     /db_xref="GeneID:96295794"
                     /locus_tag="IE233_RS39365"
                     /pseudo=""
     CDS             15809..>16523
                     /codon_start=1
                     /db_xref="GeneID:96295794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744834.1"
                     /locus_tag="IE233_RS39365"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTGLSRHHLACLVTELAAAAQWQAGTEAGLTQRAAGPCGGQLVLA
                     PGISSCESTV"
     gene            complement(16718..17668)
                     /db_xref="GeneID:96294505"
                     /locus_tag="IE233_RS32525"
                     /old_locus_tag="GCM10010326_66290"
     CDS             complement(16718..17668)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (18-186). E-value: 5.3e-31.
                     Score: 99.8. Matches aSDomain:
                     nrpspksdomains_IE233_RS32525_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:96294505"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009069096.1"
                     /locus_tag="IE233_RS32525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66290"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_190029040.1"
                     /sec_met_domain="ADH_N (E-value: 1.7e-11, bitscore: 37.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALQFDRFGPPDVIMLRDVPQPGPGPGQIRIAVRACGLTPADWH
                     IVDGLLADHLPPLPRGLGLEVAGTVDALGEGVTGVRIGDRVFGPATFHGPTAGAAEYAL
                     MPAWARIPEGVTDEQAAALPMAAETAWRALDDLGVQPGELLLVHGAGTTVGETAVRFAL
                     HRGIRVIATAGPIRAAALEEIGAQVTAYGVDMAERVRALAGGRIDRALDSTPTGGRIDR
                     ADRPSPAGGSLPTLIELTGDPDRVLTVSDFAAAAELGVRITTEIRYEQMDEFARLAGEG
                     TLVVPVARTYTLDQVQEAAELSQSRRPGGKLMLVL"
     aSDomain        complement(17111..17614)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS32525_PKS_ER.1"
                     /evalue="5.30E-31"
                     /label="IE233_RS32525_PKS_ER.1"
                     /locus_tag="IE233_RS32525"
                     /protein_end="186"
                     /protein_start="18"
                     /score="99.8"
                     /tool="antismash"
                     /translation="DVPQPGPGPGQIRIAVRACGLTPADWHIVDGLLADHLPPLPRGLG
                     LEVAGTVDALGEGVTGVRIGDRVFGPATFHGPTAGAAEYALMPAWARIPEGVTDEQAAA
                     LPMAAETAWRALDDLGVQPGELLLVHGAGTTVGETAVRFALHRGIRVIATAGPIRAAAL
                     EEIGA"
     gene            17753..18325
                     /db_xref="GeneID:96294506"
                     /locus_tag="IE233_RS32530"
                     /old_locus_tag="GCM10010326_66300"
     CDS             17753..18325
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294506"
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018843454.1"
                     /locus_tag="IE233_RS32530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_66300"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_161244646.1"
                     /transl_table=11
                     /translation="MPRWESDAQGRLERAALELFETQGFERTSVAQIAGAAGLKERSFY
                     RYFPDKREVLFAGNELEAHLVAQVEAANSGLTPIEALLTALGTAEEIFRPREFLLRRGR
                     VIAANPALAERDLIKLAAIADALALALERRGVEAGKARFIIDVVLAIHRRAMPRWLAEP
                     DTTLAQLMAQAAAELREAVALSAPTAR"
     misc_feature    complement(18836..18850)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    18973..18984
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    19221..19236
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.86"
                     /tool="antismash"
     gene            19581..19904
                     /db_xref="GeneID:96294507"
                     /locus_tag="IE233_RS32535"
                     /old_locus_tag="GCM10010326_66310"
     CDS             19581..19904
                     /codon_start=1
                     /db_xref="GeneID:96294507"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS32535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_66310"
                     /product="hypothetical protein"
                     /protein_id="WP_190029041.1"
                     /transl_table=11
                     /translation="MNESRSEPQQQDPGGLDRRGVMRGATQVGLAALTAGAILGAAEPA
                     QATPSRGVVPEAGQTAGAVGPHEPLVVHVRDAATGEMDLFHGDQHRQVYDRELATALLR
                     HTR"
     misc_feature    complement(20283..20297)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.09"
                     /tool="antismash"
     misc_feature    complement(21065..21079)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(21073..21086)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.42"
                     /tool="antismash"
ORIGIN
        1 ctgccatccg accgcccttg tcgtacagcc gcccgtagcg gcgcccgctg gtgacgggca
       61 cctggccctc ccccaccagc ggggccgacg cggtcgcggc cagacggcac ccggagcgct
      121 ccgcggctgt gctcagcgca tggcgcaggc gaagcaggtg cccggcaacc tcgggcagct
      181 cctggcacac gggggtggcg acctccacct gagcctgcaa gagctccggc tggacttcgc
      241 tctcctcggc gacgtcgtca aggcccgcag ccctgcgcac ctcctccgac cgcgcgaccg
      301 ggtgcccggt cgccgggtcc aggagcaggt attcctcttc aactccaacg gtgatcacga
      361 atccgtggta ccccgtccgc acctctccta ccggcatcta tttaggcgaa tcaagggggt
      421 ggttgccgtc gtcacctact ggcaccgccc cggctcccgc cagcggcacc ctgagctgga
      481 tctacgccaa ccgcagcccc gtcaaaacac acaacctggc ccgctggtgg gaccagacac
      541 ccggcaaaac ctctcatgac ggccgaagct ggcgcggggg caaaacggta gggacctgga
      601 ccgaggccac ctggggacgc ggcggccacg accgtggggg aaccggccgt ttcatgggca
      661 gccggatctg cgtggaattc aactacgacg ccggcgcgag tcccgagttt tggggttcgg
      721 cacagaggcg gacaggttcg ggctgcccga cggttgctta cgggtcacca ccgggcgcgc
      781 ggcacgccgt cgttgtcggg cagggtggcg cacagaagcg ggtggcgttc gtcgaggtac
      841 acgggcaggg cgcaggccgc ccgcgcgccg gccaccaggg tggcgagctc ttggtactcg
      901 gtgtcatcga cgaccgcgtg tctgatcgtc ccgtcctgtg cctcccagac gaactcagcg
      961 gatccctcct ccagcagcgt ggcaagtacc gcgccgacat cgggattcaa gtccggccag
     1021 accgtcagca gggcgcgcgg gctgagacca gtacgcaccg cgtcgaggtt ctccggcgtg
     1081 aggcggtgga aacgtacagc gttacggacg tagccctccc tcagaagcac cgccttccgt
     1141 gaggccagca cggtgtgcac gcgcgcccag aatccatcgc cggccgcctc cgtcacgtcc
     1201 ggctcctgca gctccgctgc atagggggag gtcgccatcg gttccgggaa gagaccgagt
     1261 tcccgtgtac gggccacagc gtttgcgcag agctggtcgc tgcccacgta cacgtactgg
     1321 tcccacccga catgcacggt gaacgcgtct cccgactcca gacggcacca ggcaccttgg
     1381 tcgcggagca tgccccggac caactccaga gcgaccggaa gggagacctc ggccccgtcg
     1441 tggtagccgg agaggtcggg cgggaagagt ccgccgagac catgtctccc gtccgacggc
     1501 tttacgccga agtgggcgag cccggtgact gcgggctcgc ggatctccag ccgatcgatg
     1561 cccgaggcct ccgcgaaggc ggcgatcgcc gcgaggtacg cggcttcgac cggtccatgg
     1621 tcactgaccg cctcctcggc accggtgtag tggccgtgtt catcacggtc tgcagggtcg
     1681 tacttggtga tccggtggac gaaggacggc ggcacattgc tccctgcgag gtcagaaggg
     1741 ggatcagctg ctgaggtcga acacgcccca ggtggtgaac ggctcggcct ggacgtagat
     1801 cctgcttcct cggccgacaa cccgccgacg gccggggaca gagccatcgg gcagggtgag
     1861 caggccgacg tccgttggcc cgacggatgt ttccatgatc tcgccgtggg cgagtcggtc
     1921 ccgctcttcg ccgtagccac cgtagaaggt gacccgttca ccgtggactg ccaccgcttt
     1981 ggcgcctcgt acacggttcg cccacaccct cacgggccgg tggctgcggt cggggcgtat
     2041 atcgacgagc gggaagtccg tgtatggaca ggcccaggcg gtggtgcccg acacgttcag
     2101 ggcgtagcag tcgaagaggc cggggatgcc tgcgtcgtct gatgtccaag tgagtcggcc
     2161 ggtggcgctc cagcagcgga ttcccaccgg gttctcgtcg aagtgcccaa cccagatacg
     2221 gctggcctcg tccacgagca ggtgctcgat ggcgtccccg acggagaagg ccgaggtctc
     2281 acggccgtgc gcgtcgaaga cctggacctg gttcgcgtcc tcgtatcggc gggcgcgaga
     2341 tgcggcgact acgaacctgc cgtcgggcag gcgatccaga tgcggccagc gggctcgcac
     2401 ggcgctcagt tcggtgagtt cggcgtgacc gtccggatcg acggaagcga ccagcgcgtc
     2461 aaagggacgg acagcgtcgc cagcctgcgg aacgtggtcg gcaagcagcc agtgcgcggt
     2521 gccgaaaacg tcgacggtac tggtcagaac gtgacggtca tggtgcgcat ggggcagatg
     2581 ggcgtaggga acgaggacgg tcttctgcac ggtgggctct cctgagtagg cggtcggtga
     2641 cagccaacgg gcactgcggt gcggcgacgg cggtgtgcga gcggcggaga gcggagcggg
     2701 cgcctagaag gcatggccct tactggtcgt catgaggtga tcctggtcga caaccgacct
     2761 tggaacaagc catttctggt gtagctgagc actccagttg gcaccgttcg ccgactggag
     2821 cgattgcgcg gaaagagcgt cagagggatc ggacagcgga tcatgccaag gtgacatcca
     2881 cgccgccccc ggccagggtt tcaaggattg tggtgaacaa gttgtagggc tggccgtccg
     2941 gggtcagggc atgggacagg tgctcgcgcg cggtcgcggc gtctcgccac agcaaggtgg
     3001 cgggggctgt gtagccgaag gtgccgcgca ggcagtcgtc gagggcggtg aggcagccgc
     3061 cgaagtagcc gccggggccg ttgaccgcct cgccgagcgc caggtagagg gctggttcgt
     3121 cggtgacgta ccggccgtcg agttcgtagg cgtgaccggc cggtcggtca cggtgggatc
     3181 gtcggcagcc ccggtcgcgt acaaggtcat gccaggcccc gcggcggcgg gtgtcgaggc
     3241 cggcccaggt gttcacggcg gccggtggtc cggcgagcca tcgctcccag atcgaccgcg
     3301 cgtattcggg gacgggtgtg tagcggcatc cgtcgagctc aaggtcgatc aggcccaccc
     3361 cgcaagagga tggacgccag gcgctgatcg tggtccgcag cagccgatcg gtgagcatct
     3421 ccccttggac gtcccgtatc tccagcgcgg cctcctccag gtccagggcc cgccgggtgc
     3481 ccttcgccag tgccgcactg agccgatcac tcggggcgag ccctcgcagg acaatcggtg
     3541 cgggtacctg ctcgggcggc atgatgcgga tgaactcccg gcaggagccc agccagcgat
     3601 gcccgtcgtg gacgcgaacg cgccctctgt acccctcggg cgggccttcg tagtcgtcca
     3661 ggccggtgag cagccgactg tccgtcccga cctgccccga actctccgcg tcctccagca
     3721 gccagacatc gcatgcgtca tcctccggca ccagccacac tctgctgccg acccagccgg
     3781 agacgctgga tacctccgga acccagccga acaactcgta cgtcccgcgc cggcattctc
     3841 cgaacagccc ctctacctcg gcacagacgc cccagacatg gccgtggtcc gtctcggtca
     3901 gcgcgtacga cgcgctcccg cgggccttct cgtcctcatg cacaacggag atcatgccct
     3961 gaccacgttc ggacgactag gccaggatct tcgccggccg gagccgcagg gaccgttctc
     4021 gaacgtcaag ggcagccgtc gcccacctcg caatgttcga ttcatcttca atgcgttgat
     4081 attggaggcg cacctgcagc cctcgaagca ctgcgagagg tggatggtca tgctgcgaac
     4141 ggtgtgcgtc tcgcggccca gggcgacgat acccgtctgc agcagggaag cgagacacgc
     4201 cgaggcgtct ggagaaccaa gccagtgcgg cgtgaccacc atgaacaacc acgtctggca
     4261 cggccggtgc gtcatacggg ttttcttcca cccggactcc gaccagcacg gtgcacccaa
     4321 ggacgcgttc gagcaactcc tcacgctggt tgagggcttc actccgcgca tccagccgcg
     4381 tcctgaggac ctggcggtcg acctcgacat cactggtgcg ctccgctacc tcgaccgcac
     4441 cctctacgag gccggacagg tgctggtgct gcgggcgctt gcgctcccag gagtggcgac
     4501 gacgattggt gccggcccgt cgggtcgccg atctcctccc agaccagctg ttgcttcggc
     4561 ccgttccagc cgcaaggaca taccgcgcgc agcgcggccg cacgcgcccc gtgtccgagg
     4621 cccgcgccct cgaagatgct ccgctgcgtc ggcgggatcc tcgcgaggcc cagatcactt
     4681 ggctcgaggc agcgatcacg cagctccggg aacagccgac ccagtcagag cagacggtcg
     4741 aagaactcac cgacttctgc ggccaggccg tggcccggct cgccgcccag cacgaggagg
     4801 tcgtccggct tcgcgaagcg accgccgagg agtccaaggt gaggcgccta ccaacgccgt
     4861 gaaccaccgt catcggctgc tcctgcagct gatgcctgcc ctgaaccgcg gcgaaccgca
     4921 tcgtcgatca ttcggccgct tgtctacccg cgccgctgcc gaatccgcac tccgaatatc
     4981 ggcgtagagc ctcccggcct cccggcacga aggcccattc atcggcgact tcacgcagtt
     5041 cgtccaccgt catccagtcc tgccagccga tctcgcccgg ggcgggcccc agagcctccg
     5101 acacgacggc ctcatgcacc ccgaaccaga cggggctgat cccttgccgg caaaggaact
     5161 tgaacaggaa ccgtacgggc gcacgaacgc ccagctcttc agtcagctcg cggactgccg
     5221 cctgctcata cgtctcgccc acgttcacag cgccgccgac catcacgtcg tagtagcccg
     5281 ggaaccggga catcgtctcg gcccgtcgca gcaccaggat tctcccctcc cgatcacgac
     5341 agatcgtcgt tgcaatgcgg tgcgaccagt tctcacgcac cgcctcgtcc cggtcgacga
     5401 ctcccagcac gcggtcatgc tgatcgacat actcaaccag ttcactcacg gaggcacgat
     5461 ctcagcccct actgacaacc ctgcccgacg agcacccggg gcaagcgatc cgcaccacag
     5521 gacatcccgc gcaatgcaac acgctcgacg atggcgtcgc gaacggtgcc tcgaagagcg
     5581 accttctcaa tcgccacacg agctcatccg cacacggcat ctgtgggcac aaggcattcg
     5641 tacgtcacgc atctgaccga gggtggttcg ccccgctgac ctccatcgtc tgcgcatctc
     5701 gcccaccacc agccttcgac ggaggtgccg gctctcgccg ctactcggca cgatgccgag
     5761 ttggccaccg cgtggcgcaa ccggagacgg tcgtcgaacg cccaccggag aagcgcttcg
     5821 tggcatcgac catggcgccg cacagaactc ggtatctggt acccgacctc gacccagcga
     5881 accaatgcgg tcacagtaat agcgctgtga acagcgctaa atatggatga ggatctgtcg
     5941 gacgggatgt ccgagcgcac ccgcgagaga ggccagctcc ccgttggtca gccaagcccg
     6001 gttcggatac aaaatctcga tcctgaaacg cgcgaacccc atcggccagt cgtacaccag
     6061 ctcgttaagg gatgtctcag cgtcgcagca gggaaccgtc accttcaggg tcgaaaagcc
     6121 cccgtcgtag cactgtgaga cggcatctcc ccaccaaaga ggtgtgagtt ccgtgccgca
     6181 ccgcgggcag gagatcctct ttaggttggc gcagcagtgc acgacctcaa cgctgtcgtg
     6241 ccacttggcg tccagaccac gtcgggcgtc gtcgtcagaa agcatcccgg acaacaccac
     6301 cgcagcacga tccgccgcat ccttaccggg ctgccagtaa ggatcggtcg gaattaccgt
     6361 caggtagttg tcactcatac cccgccccgt tcccctctac gtcgcgtcgt caaacccagc
     6421 gaacctattc cgtagtcaag ggcgtgcagt ggagctgagc ttcaggggat gctcgagtag
     6481 agcgctgcga tgccacggcg aaccgggtct gccgggtctc cgcatactgc ggcgcacggt
     6541 ccgcgtactc agggtggtgg cagctgcgcg gacgccggac gtgtgccttg agcgcgcctg
     6601 gcccacacgg aacggccttg accgtcgatc aaccacacgt ccagcgggcc ttgaggttcc
     6661 tcgtctccgc tccggtgcca tgcagcgaag acctcctgca gccgacgacc gaccaggagc
     6721 tcaggacgta cgccagaccc gtacgatgga cactggttca ccttcttgta ctccacacaa
     6781 cgaccgtacc gtcagtcaac gtcccagctc acacgcttaa acgggacagt ccctactgat
     6841 tttttcgtaa gttcggtggg tgtggtgggc ggatggtcag gccggtgtgg gtgaggaatg
     6901 accaggggag ttgtgggttg gtgttgatgc ggtggatgcc ttgttcggcg gcgtcggcga
     6961 catcggcgag gtggtcgccg gcgaggttgg cgagttcacg tttcttgatg gaggaccaca
     7021 gcaactccac tgggttcagc tcgggagcgt aggcgggtaa tcgctccaga gtgagccagt
     7081 cctgctcggc gacccaggcc cgcatggccc ggctccagtg ggcggacagg ccgtcccaga
     7141 ccagcaccac gttctcaccg cggtagaaca ccttcatctg ctccaggacc tcggtgagtc
     7201 cgggagtgtc gtagctgccg ggcttgagat ggaaacacgg tcgtgcaccg cgttcggggt
     7261 cggttgagtg atagcccaaa gccccggcca tcgacgcccg tttccagttc aggcggtgcc
     7321 gaaggagcgg ggtccgtcct cggggcgcgt aggtgcgacg gacctgcggc aggagtgaga
     7381 cgcctgattc gtcgaggaac acgatccagg cacgtgtgtt caccgccctt ttttgatctg
     7441 cggccactcg tgcgcgaccc agcgggcgat ctccgattca tcccgctcca ccgcccgccg
     7501 ctcgggccgc tgcagactcc atcccagccg gcctgtcagc agccgccaca ccgatgcccg
     7561 cgacaacacg acccccgtca cccgggcaac gacttctccg acacgttcca gagtccacag
     7621 gtcggcctcg aaaccatgag cccgggcacc ttgctccaac gcggtccgaa ctgcctcgac
     7681 ctgggagtcg tccagcttgg gcgggcgccc ggtagatgcc cgtcgccgca acgctaaagc
     7741 accgtccttc tcccacaccc gccgccaacg ccgcacgctc tcggcacaca ccccgaccgc
     7801 ccgcgcgacc tctacgttcg agacaccctc ctcgaacaac tccaccgccc gaacgcgacg
     7861 cgcttccgcc aactgcggcc gcgacaaagg aggaagagga gatccggcgg ccaaaggcga
     7921 aggttggtaa gccatcccga cagcgtccca cctacaccgc caccacaccc accgaactta
     7981 cgaaaaaatc aataggagga cttctgcgag atctgagtcc agacgcataa ctgcgaccgc
     8041 gtgtccctcg acatgcccca gcacgacgtg gagtacgccg ccccgtactc ccccggaagt
     8101 tgtacctcca ccacttggca tgtggtcccg ttggtgaacc tgccacggct cacgcccgtc
     8161 gctccgcacg atcgtggcgg cgcgccgctt cggctacctc cccctcgccg ttccgcttcg
     8221 ccgtttcctg ggcggcgggc accgcctggc gggcgaggtc gacgccgctg agctcgggct
     8281 gagcggtcat cagccatcac cgcctcggtg agctcctgcg tacggtgccg cacacgcacg
     8341 atccggtcgg gcagcggcgt acggctgcac ttctcgtgcc cgtcacgacc tgcgcaccga
     8401 cccactgcgc caaaggccgg taccgcagtc gactccgcct cgcacacttc tcgttcgtcg
     8461 cggcacggct tgcacagacc ggtctccggg cgaccgcctt cgcactcggc ctggcctgcg
     8521 cgtatccggt agctcccgga gccagggcca acagatggcg caggacgtgg cgcgacagat
     8581 tgtgcagcgg atacgcactg atctcccccc gaggctcgct cagggcgctt gatcagcgcg
     8641 gacagtgagg ggtgtcagtc gccggacttc acgggctcca gtttgatgct gaagtgccgc
     8701 aggatcgggg actggctcgt cacccggtag ccatggaccg attcaggatt cttcgcgata
     8761 tctgccaggg tggcggcgac gtggtcgtag tggctgcggg tgtagacccg cctgggcaga
     8821 gccagccgta caagttcgta gggcgccgtc ttgacagggt tgccgtgctc gtcctcttca
     8881 ccgaggtaga gcgaccccag ctccgccgag cggatgcctc cgcgcaggta gagctcgcag
     8941 acgagtgcgg tgccggggta ctggtgcggg gggatgtggg gcaggaggcg cccggcgttg
     9001 acgtagaggg cgtgcagacc ggcgggttcc acgatgtcga cgccggcctc gcggatgcgt
     9061 gcggcgagat agccagctat gtcggcacgc tcggcgaggt aggccggctc ggtgacttcg
     9121 aggaggccgc gggccatcat gtcgaggtca cgtccggaca gaccgccgta ggtggtgaat
     9181 ccttcggtgg cgatgagcag acccccgcac cgctcggcga gttcggcgtc cttcaggccg
     9241 atgaagccgc caatgtggac gatcccgtcc ttcttcgcgc tcatgacgca gccgtcggcg
     9301 aggcggaagg cttcctcggc gacctggcgc ggggtgcggt gggcgtagcc gggttcgcgc
     9361 tgggtcacca gccacgcgtt ctccgcgaac cgggccgcgt cgaggatcat cggcacgttg
     9421 tgacggcggc acagttcggc ggtgcggtgc agattgtcca tgctgaccgg ctggcccccg
     9481 ccaccgttgt tggtgatggt catcagcacg gccgcaacgg gcgtctggtc cgcgttctca
     9541 agggcctgtt cgagggcgat caggtcgatg ttgcccttga acggaaagtc gctgtcgagg
     9601 tccttcgcct cggcgcaggg caggtcgtac gccgtgcagc ccgtcagttc gacgttggcg
     9661 cgggtggtgt cgaagtgcgt gttggacagc acgctcgtgc cgggtcgcag cagcgaggag
     9721 aagaggatgc gctcggcagc gcggccctgg tgggccggca ggatgtgggg gtagccggtg
     9781 agttcggaga cgacctcgtg ccaccggtag aaggagcggc tgccggcgta ggactcgtcg
     9841 ccctgcattc ctgcggcgag ctggtctgcg gagatggcac cggttccgga gtcgctcaac
     9901 aggtcgatgg tgacttcgtc ggcccgcagc tcgaaggggt tgtaggcgac ccgcttcagc
     9961 gcggcctcgc gctcctcccg agtggtgaaa gcaaggggtt ctacgacctt gatgcggtag
    10021 ggctccacgt gacttccttc tgtgcggtgt gcggactgac gtggccggcg gcctggtgcc
    10081 cgaggtccag gacgctctgg gtgcgttgcg caggcatcca ggtgccccgc gggtactggt
    10141 cctgcggctt ccggacgcgg taggcctcgg aactcaggta ggcggtgagc cggggcggcc
    10201 ggttgcgctc gtacaccagg gcgaggtagg cgatcagccc cacgccgtcg gcgagggatc
    10261 gctgggtgag cgctccgaga cttcggttca ggacggtggg gtccatgccg gcccgggtca
    10321 gcagggctgt ggcgcgggcg agggcctcat cgtcgtcgcg cacgtagtcg cgcaccggaa
    10381 tgtggagcgt gaagccgctc gggtcgctgt cgcctccggt gaaggagtgg caggtgagcg
    10441 ccggccgccg caccagtcgc agggggtcgt ttccgccgcg ctcggacggc gcgagggagc
    10501 ccgcggccgc atggaagaag tagcggacgt cggcctctgt ggctccggaa gtacggctga
    10561 gcgcgcaggc gtcgtcggcc gatatgcgcg ggtgtctcac gtagaccttg acgcgggggg
    10621 acgcccaggc gcccaggtca agagcgagga acggatagcc ggccgccgaa ggcagccgct
    10681 cgaaggcctg gccgtagccg agccgccgca gtgcctcgtg cacagtgcgg gccgcgtttt
    10741 cggggccgga ggcggaggga ttcaggtaga ccttgacgcc tgggacccct ccggcgcgca
    10801 gatcgagcgc gtaccacagg gccagggggc cctgggccgc agtggggaag aacaggtcgg
    10861 cgagggcgtc gagttggtcg gtgtcgaagc cccagcgggc gcccatggcg cggatgaccg
    10921 caagcccggc gcggccgttg tcggccatgt cgccgtgcgc ccacccgggt tcgacgagca
    10981 cgcgcagggc cggggcggcg tccggagtgc tggcgaggga gaactcgacg ggggtgtggt
    11041 cgtcggagag gaaggcgggc gaggccggcg gcagggacag cggccggtgg gcggcgcctg
    11101 caagggagtc gaccacgacc cgtccgtaca gctcggtgtc cgcctcgctc aggcccaccg
    11161 tggcacccag gcgccgtagt tgactgagta cgtggtggcc gagcgtcgtc tcaccggggc
    11221 ttgtcgccgg tatgccgggg cccgggcgga aggtcatcgt gtgcctcgca cgacgtggcg
    11281 cgttacgcgt ctggacggtg cgggggtacg gggacgtgcc ccgccgacaa gggaggagac
    11341 gagggctgat cggctgccgg gagcagcggg tattcggtcc ctcggctggt cggggccgcc
    11401 gcccccgcac cggttccgtc tgctgggggt ggtgcgctgt gggcccggtc gggcgctcac
    11461 ggatgggggc gcggagatgc ttacgaggtc cactgcctct ccttcatctt gagtcactcc
    11521 agacactccg cgccgttcta cccaggaagt tgatctttca tgcaggctat atcaactgcc
    11581 tgtgccacac gcatcacagg gggtgtgggc tactggcccg tcagccactt catgaagctg
    11641 ctccagcgcc ccgctttgcc gacgggctgc ggcgcggcgg gcgtagatgc ggccgcgacg
    11701 ggagctgccc ggtagcgggg cgccatcgtc gcctccggtg ccgccgcggc gcgcggggtg
    11761 accgcgctga accggacggg cagggaggcc agggcccggt tgaaggggcc gggccgccag
    11821 gccaagctgt ccgcggggac ggcgagttca acgtcgggca gggcgttgaa cagtgtctcc
    11881 aggcccgtca gggcgatcag cctggccggc tccttcgacg ggcaggcgtg cggccccgcg
    11941 ctccaggcga ggtggccgcg ggtatcggca ccgcggtccg cgagcgccgt gttggcggcg
    12001 ccgaaggaca ccagcaccag gtcaccggcg cgcaccttgt cgccggccac gtccgtgtcg
    12061 accaccgggt aatggggcgc atagttggac atcggcgcat tgcgccacag agtgtcgtcc
    12121 acagccttgt cgaactgccc caggcgcgcg aactcctcgt tggtcagcat cgtgtagaag
    12181 gcgtttccga tcaggttgcc ctccggctcg ccgcccgcac cgaggagcaa caccagggtg
    12241 tgcgccaact cctcgtcgtt caactgcgcc tgatgctgca tcaggtaaga cgtgacgtcc
    12301 tccccgggct gggcgcgctt gagcgccacc agctcgccga ccgctccgag caggacctgg
    12361 ctcgccgcct cggcgttgac tccgtcgaac atgccggaga tgccgaacag cacccggtcg
    12421 ccgatctccg gcgggcagcc gaacagctcg ttgaacacgt acagcgggag ctgctgggcg
    12481 tagtcgcgga gcaggtcggc gctgccgcgg gcgctgaact ggttgatcag gaactgagct
    12541 gcctggctga cgatccggct cagccgcttg ttgctgacgc gggcgaagga gtcggtgatg
    12601 gcctgccgca ggcgcacgtg ctcggcgccg tcggtgaaca tcgcgttcgg ccggtaggcc
    12661 aacagcggca ggaccgggct gtcggggcgg atgcagccct cggccagtgc acgccagcgg
    12721 cgtgagtcct tgcgaaaggt cgtcgaatcc tggagcagtt ccagagccgc gttgtaatcg
    12781 gtcaccagcg tcgcctccac gccgggggcg atggtgaccg cagcggtggg gccgagctcg
    12841 cgcatgtagc ggtagtacgc gtgcggattg gcagcgaact ccgcgctgtc caggggtatg
    12901 cgctccccgc tgccgtgtgc ggggcagccg ggcggaggta cagagggggt tgtcatgcgt
    12961 gctccaggtc ggcgcgctcg tgcagatagc ggaccaaggt gatcagggca tcgacggacg
    13021 acttctcgtc gcgtgcgtcg atggtgacga cgggggtgtc gggcagcagg tcgagcgcct
    13081 cccggacttc ctccggggtg tggaacgtac tgccgtcgaa gtggttgatg gccacggcga
    13141 aatcgaggcc gtagctctcg accagatcca tgacgtcgaa ggagtcggcc aggcgctcgg
    13201 ggtccaccag gaccagggcg cccagcgctc cgcgggccgt gtcgtcccac aggctcacga
    13261 agcgctgctg tcctggggag ccgaacaggt acaagacgac gcgttcgctg agcgtcagcc
    13321 ggccgaagtc cagggcgacg gtggtggtgg tcttcccctg aacccccttg aggtcgtcga
    13381 cgcgctctga gagcgtcgtc atccgctcct cggtggacaa cggcgtgatc tcggaaagtg
    13441 agccgatcag ggtggtctta ccgacggcga aatgcccgac gatcaggatt ttcactgctg
    13501 tctgctgtgc accactgggc acgtaggcat cctcagacag tgagagcctt gaggccatcg
    13561 agcacctcct tgagcaaggc cttgttggtg ggacgggccg agggcaccgg cgcccggacc
    13621 acgagatagc ccccctcggc gagggagctg agcagcacct tgaccacccc gagcggcagc
    13681 tgggagtgcg cggcgatctc ggcgatcgag aggtagccac tggagcacat ctccaggatc
    13741 tgctgctcct cgggcgagag ccgctggggg cgctgctgct cgtcggtggc cgccgtgacg
    13801 agagtgatga gggcgaactc gccctcgtcg ggcaggtcac ggccacgggt gatgacgtag
    13861 ggccggacta attcaccggc ctcggacacg aactcggtct cgggacggcc gggttccgtc
    13921 atgaggtgac cgtgtcgccg cgaaggccgg tcgacatcgc cttgcccagc cggctgacca
    13981 accgctgcat ccggtacgtg atgtcctgca tgtcgacctc ggccgacgcc gccacggcca
    14041 ggtagctgcc gccgcccgca gcgttcagga acacccagcc tccgtcgaac tcgatgaggg
    14101 tctggcgcca gttcgctccg tgctcaccgc agaagaagcc gacggcccgg ctgagcgact
    14161 gcaggccgga gaccgcagcg gccaccttgt cggcatcgcc cctgtcgatc tccgcagtac
    14221 gggacatctg gaggccgtcg gcggaaatca ggaccgcgtg cagagcatgc ggaatctgca
    14281 gcgcgtcctc aagcatccag gacaggtcat cgctcacggg gcatcgaatc cttcgtgtga
    14341 atcggcggtc gtatcacctt cggcggccgg tacccccgca cctcggccac tgagagtgcc
    14401 acgctgaaac gcgcctatgg ccgccacccg tgcctctgct gaccgggccg ggggcgcctc
    14461 atcagacgtg cggccgccgt ccggcacgag cgccatcccg cgcttgttcc gtcgccgggg
    14521 cagcccgccc tctgtcgccg cagaggccga accacggctc gcggcaatgg cattgacctc
    14581 ttgcgtggtg gtgggcgtct taggctccgg catctccgtc agcaactcct tcggcaccat
    14641 caccaccgcg cgcacaccgc cgtagggcga ggtgctgtcg atggcgaccg tgaacccgaa
    14701 ccgcgcacac agggcaccga tcaccgcgaa cccgaacgcg ggaggattgc caagctccga
    14761 aacgctcacc gcagaaccgc tggacagcag agcggtggcg ttcgtccgtt cttcctcgct
    14821 catgccgaca ccggcgtcgt cgatcacaat gcagatgccc cggggcaccg tccgcacctc
    14881 gacctcgacc atggtggacg gctcggaata gctggtcgcg ttgtcgagca gctcggccac
    14941 cgtcagcgcg atcggttcga cggcacggct ggtcaccgcg aaatcgaccc gtgaggcgat
    15001 ttcgatgcgc tggtagtgcc ggacacggcc ctgcgctccg cggatcacgt catagaccga
    15061 tgcggcctcc cgctgccggc caagccagcc accgcacagc acagcgatgg actgcgcacg
    15121 ccggttgaat tgcgagttca tgtggtcgat gtccagcatg tcccgcaaca cagccgagtc
    15181 gccgtacttc ttctgcagtc ccgagatggc ccgctgctgc tccgcggcga ggccttgaag
    15241 cgtccgcatg gccgacttca gtacggtgtt cgtggcctcc tccgcctctt ccttagcctg
    15301 gcggaccact tcgtcgtagc cgctgcgcag ctcggtgacg gtggactcga ggtcggcggc
    15361 tctgccctgc gatgcggtca gctcaccttg aaggccctgc tcttgacgac gtagcgcctt
    15421 gatctttttt cgctggcgag cgattaccgt agcggcgaca gcgacaccga cgacaagcgc
    15481 ccagactgtc ggatcctgcc aaaaattcgt catgtgactc tctattgagc ggctggaatc
    15541 cagctctcga aatctgccca agcggaccct cggctgtggg cagacgtcac cgcccggaga
    15601 gcccccctgg ctggagccat gccaaggcga aagctcacgt ggcatgtgca cgcgagcgta
    15661 tcaccggacg atcacgacgc tccgtcaagt ccgtcacggg ggtgtcctgt tggcgagaaa
    15721 cgcacgtttt ttgcttcggt gagagtcccc tgccaggacc cgtggccgcg ctgtcctcgg
    15781 gcggagggcc agaccagccg ctcagcggat caccggactc tcgcggcatc atctcgcctg
    15841 tctggttacg gagttggccg cggccgcgca atggcaagcc ggtaccgaag ccggcctcac
    15901 gcagcgcgcg gcgggtccct gcggcgggca actggtgctg gcacccggca tcagctcgtg
    15961 tgaatcgacc gtttgacggc gcctctcatt gacatgcgca acctcccggc cgagcgaggg
    16021 tgcgcggtcc ccgaccggcc ggccctgcat ctgcatccgc gaaccccgcc cgatgtcttc
    16081 gcctatgccc agaccgaagg tagcgagttg cgtctggacg ccaccgagat ccaggcccgc
    16141 cggtcacctg ccggtcgcgg agggcggcgt gcgttcgtct ccggcaagaa gaagctcagc
    16201 accgtcaagg ccaccgtcat cgccgaccgt cgcggccgca ccttatggac cgacactctg
    16261 cggcctgggc ggtgcatgat gcgaccgccg tccgcaacga aggaatcggg atctgcttcc
    16321 accactatgt cgatgtcgaa gtcctcttgt acgacagctg tctcgggctc cgctcgtgat
    16381 tacctgccca ggcggtcacc ccgccgagga agggcaacaa gaccagcccg cccgaagtcc
    16441 ttggaacccg tcagcgagcc cgccaccggc actcctcgaa atgcatcacc gtcgaacacg
    16501 ccctcgccga ccacaaacgc tggtagcacc ggccgtgaag cgcttggatc acggtggcga
    16561 atcttcagcg ggaactcgag ggttcaaaga cgtctttctc gggggttgac ccgtaggttc
    16621 acggcgaaca cgcgggtgcg gcttcgtggt tggaccggaa acagtcctgc cccctctcct
    16681 cgtcgcggtg gtatcacttg tcaggccagc agggcgttca caggacgagc atgagcttgc
    16741 cgccgggtcg gcgggactgg ctgagctccg ccgcttcctg aacctggtcg agtgtgtagg
    16801 tgcgggcgac cggtacgacc aaggtgcctt cgccggcgag ccgggcgaac tcgtccatct
    16861 gctcgtagcg gatctcggtg gtgatccgga cgccaagctc ggccgcggcg gcgaagtccg
    16921 agacggtgag gacgcggtcg ggatccccgg tcagctcgat cagggtcggt agcgagccgc
    16981 cggctgggct gggccggtcg gcgcggtcga tccgaccccc ggtcggcgtc gagtcgaggg
    17041 cacgatcgat gcggcctcct gccagtgccc tgacacgttc ggccatgtcc acgccgtagg
    17101 cggtcacctg ggcgccgatc tcctccaggg ccgcggcccg gatcggcccg gcggtggcga
    17161 tcacccgaat gccccggtgc agcgcgaagc gcaccgccgt ctcacccacg gtggtgcccg
    17221 cgccgtggac gagcagcagc tcgcccggct ggacgccgag gtcgtcgagc gcgcgccacg
    17281 ccgtctcggc cgccatcggc agtgcggcgg cctgctcgtc ggtgacacct tcggggatgc
    17341 gtgcccaggc cggcatcaac gcgtactcgg cggcgccggc cgtcgggccg tggaaggtgg
    17401 ccgggccgaa cacgcggtca ccgatccgga cgccggtgac gccctcgccg agcgcgtcga
    17461 cggtgcccgc gacttcgagg ccgagcccgc gcggcagcgg cggcagatgg tcggcgagga
    17521 gaccgtcgac aatgtgccag tcggccggtg tcaggccgca cgcccgtacg gctatccgga
    17581 tctgaccggg ccccggcccc ggctgtggga cgtcgcggag catgatcacg tccgggggcc
    17641 cgaaccggtc gaactgaaga gccttcatgg ctatctcccg agtgataaca gcatctgttg
    17701 tcattgaaag taccatcgtg acaacagatg ctgttgtcgt accctcatgg gtatgccgag
    17761 atgggaatcc gatgcacaag gccgactcga gcgcgcagcg ctcgagctgt tcgagacaca
    17821 ggggttcgaa cgaacctcgg tcgcgcagat cgcgggcgcc gccggtctga aggagcgctc
    17881 cttctaccgt tacttccccg acaagcggga agtcctcttc gccggtaacg aacttgaggc
    17941 ccacctcgtc gcccaggtcg aggcggccaa ctctggcctc acgccgatcg aggcgctgct
    18001 gaccgcgctg ggaaccgctg aggagatctt ccgcccgcgc gagttcctgc tgcgccgggg
    18061 aagggtgatc gccgccaacc cggcactcgc tgagcgcgat ctcatcaaac tcgccgcgat
    18121 cgccgacgcg ctggctctgg cgctcgagcg ccgcggcgtc gaggccggca aggcacgctt
    18181 catcatcgac gtggtgctgg cgatccaccg gcgcgccatg ccccgctggc tggccgagcc
    18241 ggacaccacc ctcgctcagc tcatggccca ggccgccgcc gagctgcgtg aggcggtcgc
    18301 gttgtcggct ccgacagccc gctgaatcgg cccacgactc ccgaagctgt cgcgagcacg
    18361 aacccggcga gcgcgtcggt ctcgaactgc tccagctact ccgctgtgac cggatcgcgg
    18421 aactcgccca ggtcgcgtac acagacgcag tgccaacccg agcctcctca agttcacccc
    18481 gatcgcagac agatcggacg aagtgagaac tttgcaagaa ccctgaagtt gggcgggggc
    18541 cgtaccgaaa aggtcggcgg ctaccacgat gcggccatcg ggagcccttt cggacccgga
    18601 ctaccgctcc aggatcgacg gccactacgc catccgcgtc tgcgtgaccg ccccctaggc
    18661 gtcacacgac cagcacctcc cacaacacgg agccgtcact ggagcactta cgcccgtgac
    18721 ggcccagact tcctccactc tgaccagacc gcgtatgcca ggaaccgaca ggcacggtcc
    18781 cctcgtcgtc acagtacgag aactcggtac gcacgggatc aggggattga caccgatcgg
    18841 cagccatgat ccaaattgtc gccatcaacc gcatgacccg acgcctcacc caccggatta
    18901 cccccaactg acgcgacatc cgaaccaaat gaaacagaag cctttcgcga ggcgggaagg
    18961 ccgtacgcaa taggaaacgt tgtccttggg ctcggcacaa ggcccgcagc cgcgcggtct
    19021 ccgcagcacg aaataccgaa tcgctggccc cgtcagcgac actctgcccg gatccgccag
    19081 ttggcgaaaa tcactgtgcg tacaggcgaa actgtatcga gcaggggcct caacgcactt
    19141 atgcaccagt tgagttgacc gcagccggtg atcgcctcct tctctttccc atctgccgct
    19201 attggttcga tgcaggcgcc gtgacggttt ggtccgatgg gcaaaaatat ttgccttccc
    19261 tcattcagcc gagcacgttg ggcctgaact gcgacaacac agatgcctca cggcacgcgc
    19321 caagttccgg cgggttcagc gtccttgacg gggcgtggtg gggggcgttt cattcggggc
    19381 tgagcgtcgg gtccccttct gcctcgggcc cagcgtctgc cgtcagacgc gtcatcgacg
    19441 ccttcaatcc ctttcgcgga ccgtggaaac gcctacctca ggacgccatg tctgctcgtg
    19501 cgtcgattcc tcctggccgt cggcgcaggc accgctctga tcagctcacc cgcacggtcc
    19561 gcccagccac aggagtgatc atgaacgagt cccgttccga gcctcagcag caggatcccg
    19621 gcggattgga ccgccggggc gtgatgcgcg gcgcgacgca ggtgggcctt gcggctctta
    19681 ccgccggcgc gatcctgggc gcggccgagc ccgcccaagc aaccccctcg cgcggtgtcg
    19741 taccggaggc cgggcaaacc gctggagcgg tcggaccgca cgagccgctg gtggtgcacg
    19801 tacgtgacgc agccaccggc gagatggact tgttccacgg cgaccagcac cgccaggtct
    19861 acgaccggga gctggctaca gctctgctgc gtcacacccg ttgaccgcac catcccccac
    19921 cactgcggca gtccgtgccg cgtcgccttc gacccacccg gatgaggttt gatgtcctcc
    19981 caccgcgaag ccccggagat ctccaaggac ccggtcgccg acagcaccga cgtctacgcc
    20041 ttcgtcagcc ccgacgcacc ggggaccgtc actctgatcg ccaactacat ccccctacag
    20101 aaccccgcgg gcggaccgaa cttctacgag ttcggcgacg acgtgctcta cgagatccac
    20161 atcgacaacg acggtgacgg ccgcgccgat gtcacctatc agttcgagtt caccaccaag
    20221 atgcggcgcc cggacagctt cctctacaac accgggccca tcctcgccct ggactcgccg
    20281 aactggaacc gctaccagac ctacaccctg acccgctccg agagcagcgg ccggcgttcg
    20341 gtcctcggcc ggaacctggc ctgccctccc tgcaacatcg ggcctctgtc cacgccgacc
    20401 tacgcgaagc tggcccagca ggcgatccac acgctcggca agaaccgcaa ggtgttcgcc
    20461 ggccagcgcg ccgagggctt ctacgtcgat ctggggtcca tcttcgacct cggcaacctg
    20521 cgccccttcc agaacctgca caaccagttc ggcaccggcg ccttcagcga gcccgccgac
    20581 ggggtcaaca cgaccaagga actcaacgtc cactcactcg cggtccaagt cccggcaacc
    20641 gacctcacct tccacggacg ccccgccaag gaccccgccg acccccacgc caccatcggc
    20701 gtgtggacga gcgcgagccg ccgccaggcg cgcgtcatcg agccccggca gggcaaggaa
    20761 ctggagaccg gcccctatac gcaggtctcc cgcctgggca accctctgtt caacgaggtc
    20821 ctcgtcccgc tcgggcacaa ggacgaatgg aacgcgctcc cgccggccga cgacaagcgc
    20881 ttcgccacct acgtcgcgca ccccgagctg gccaaactcc tgcccacgct ctaccccggc
    20941 gtctttcccc acctcgacgc gtacaacaag tccggaaagc cgcgcgcgga cctgctcgcc
    21001 atcctgctga ccggcatccc cacgggtgtc gtgccagggt tccagaacta caccggcccc
    21061 acccaggccg acatgatccg cctcaacacc gccatcccgc cggccaggaa ccccaacatc
    21121 ctcggcctca tcggcggcga cccggcaggc ttccccaacg gccgccgtgt ctacgacgac
    21181 gtcgtcaccg tcgaactgcg cgctctcgcc ggggccacgc tcccgctcgt cgacaagagc
    21241 tacgcccccg acgcggc
//
