LOCUS       NZ_BMUU01000015        22495 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence15, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000015
VERSION     NZ_BMUU01000015.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 192596)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 44991
            Orig. end                         :: 67486
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22495
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22495
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22495
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12495](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12495)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    462..477
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.1"
                     /tool="antismash"
     misc_feature    783..796
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    1167..1182
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.58"
                     /tool="antismash"
     gene            complement(2067..2912)
                     /db_xref="GeneID:96294424"
                     /locus_tag="IE233_RS32100"
                     /old_locus_tag="GCM10010326_65390"
     CDS             complement(2067..2912)
                     /codon_start=1
                     /db_xref="GeneID:96294424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010276840.1"
                     /locus_tag="IE233_RS32100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65390"
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="WP_190028989.1"
                     /transl_table=11
                     /translation="MSDKSRKPAHRLSKRNRYIGWGVAGVAVAATGGLIAQSASAAPAW
                     PAQKTFTGLAFDTCAAPSAAAMKAWKPGPYGAAAIYVGGKNRGCSQPNLTASWVKTVTA
                     QGWKLIPLYVGAQPACQTGKSPEKMTAASASSLGASDGADAVAKAAALGMKPGSAIYLD
                     MEPYDIKNTSCNNAVLAYVRAFTKTLRAKTYRAGYYGFSTTSAHAVATAANRTDLPGNL
                     WYAKWDNANTTTSDWPWASKLYTDHSRGHQFMVNSKETRGGYTITVDRDAWDAPVAITG
                     "
     misc_feature    3354..3369
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    complement(3356..3369)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.19"
                     /tool="antismash"
     gene            complement(3715..4107)
                     /db_xref="GeneID:96294425"
                     /locus_tag="IE233_RS32105"
                     /old_locus_tag="GCM10010326_65410"
     CDS             complement(3715..4107)
                     /codon_start=1
                     /db_xref="GeneID:96294425"
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /locus_tag="IE233_RS32105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65410"
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="WP_229892992.1"
                     /transl_table=11
                     /translation="MTREDTTGFVRKASGALTAMTSGGASQYYLTDVQGSVIGLVDASG
                     KRTATYSYGLYGEARTTSGTNQPYRYTGTYLDPSGLYKMGARYYDPQLGRFTQPDPSGK
                     ESNLYAYAAGDPSTRRTRTACPFSMP"
     gene            complement(<4128..5384)
                     /db_xref="GeneID:96294426"
                     /locus_tag="IE233_RS32110"
                     /old_locus_tag="GCM10010326_65420"
                     /pseudo=""
     CDS             complement(<4128..5384)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008736107.1"
                     /locus_tag="IE233_RS32110"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65420"
                     /product="ISAzo13 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRISDEVRDQLTLKFAVLFPHLDERQRRLLMGAEARILGHGGIRA
                     VAQVAEASEATVRKGVDELEAGAEPLGRVRRPGGGRKRAAEVDPGLRPALLALVEPDMC
                     GDPMSPLRWTTKSTRALADHLTRQGHRISADTVADLLREEGFSLQANAKTLEGAQHPDR
                     DAQFHYINEQVKEHIAAADPVISVDTKKKELVGPYKNGGREWEPKGAPAQVKTHDFLDR
                     QGPGKAIPYGIYDVAANSGWVSVGTDHDTAAFAVASIRRWWQARAGHDYPQADRLLITA
                     DAGGSNGYRPRAWKTELAALARETGLEITVCHMPPGTSKWNKIEHRLFSHISMNWRGRP
                     LTSHDVIVNSINATTTHTGLTVHAELDPGTYDTGIKVSDTDIDSLPMHRHRFHGDWNYT
                     LHPQHHDTAGAAEDPRPAGP"
     gene            complement(5451..6265)
                     /db_xref="GeneID:96294427"
                     /locus_tag="IE233_RS32115"
     CDS             complement(join(5451..5923,5923..6265))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294427"
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009332786.1"
                     /locus_tag="IE233_RS32115"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_190029058.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MGSGRWGWIVPDGLWELARPLLPPARVRPQGGGVANIDDEAVFAA
                     IIYVLVSGCAWRALPPCFGASKSTVHRRFAIWSRAGVWGRLHQKVLQLLDEQDLVDLSR
                     AVLDSAHVRAKKGGEHTGPSPVDRGKPGSKMHVLSDANGLPLRVGLSAANTHDSLALKP
                     MLSHFHMGHESHAADSKPVRLHADKAYDIPHLRRWLWGKRIGVRIARKGIDSSERLGRR
                     RWVIERTMSWLTGYRRLNHRYERKPGNYLAFLGLASALCCYKRFLKLTM"
     misc_feature    complement(5828..5830)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6089..6091)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6293..6306)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     gene            complement(6394..7659)
                     /db_xref="GeneID:96295792"
                     /locus_tag="IE233_RS39350"
                     /old_locus_tag="GCM10010326_65450"
     CDS             complement(6394..7659)
                     /codon_start=1
                     /db_xref="GeneID:96295792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070784.1"
                     /locus_tag="IE233_RS39350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65450"
                     /product="DUF4157 domain-containing protein"
                     /protein_id="WP_373300270.1"
                     /transl_table=11
                     /translation="MYANEQARTPDGKRPARTPASTRAHGGSAQAAPFALQAAAGNAAV
                     VQMLRAAGHPWAQEQHQHNAGCGHGAEASVVQRSAAHEVLRTSGRPLDDSTRAEMESRL
                     GADFSDVRIHTDRAAQASAAEVGARAYTSGSHVVIGDGGGDKLTLAHELTHVIQQRQGP
                     VAGTDNGSGLRVSDPADRFERAAEANAARVMAEPVPTQRRVREAHGAGSSTPASTSVNT
                     REAPIQRAQITEGDATVQLGNRVTSREAIVYVERDYVYKVFTSLPQGRTVAKRTREAAA
                     AGVPVPNWTGMETTYTDGPSSVPAYVIRMKKVSGTFFQLSKPGHEKIFKRLINEITDLN
                     RLHRLHGQLASVKEAQMTDVQGFLTNNPQDGEIFFLDIHASDGGGGSVDPLIAEADARI
                     ARLKDARTALVAERIGAAPGSA"
     gene            complement(7977..9944)
                     /db_xref="GeneID:96294428"
                     /locus_tag="IE233_RS32125"
                     /old_locus_tag="GCM10010326_65460"
     CDS             complement(7977..9944)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294428"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="IE233_RS32125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65460"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190028990.1"
                     /transl_table=11
                     /translation="MTDTAHRSATRETLTTSAPGRRLRLPWPRRRPTGGEPIPQYTVSA
                     ERHDNALADDFTTIARRLPALAATALRLAWDADRRAVLLTAVLQLATGVITAGGLYATR
                     GALAPLLSTGPTEERIQTALPSLALITGAAVGRSLVAATTLAVTARIGPRVDAIAELRY
                     LNAATRVPLAAYDDPAWCDHSEAANRASKDAHLMIDALTALTAAFLGLLAAAGILTALH
                     PLLLPLLLLAVIPRGAAAVRGARAAHLAERHTLSDRRLRHNLIYCTAGRATALDVRANT
                     MRSWLLGQFTTVTDRLTAHAARIGRTTARYQLFGDTMAGGAALVVYGTLLALVLDGHIP
                     AAAAGTAFIAVQTCRLLLGQLVTGINSTYKTGLYLGDWSTFLTDAEHRSQLPATPVPVP
                     DRPAVIAARNVTFRYPGSALPVLEDISVTVRRGEVLAIVGANGAGKSTLAKLLAGLYTP
                     TTGTVTWDDVDLAGADPEQVWSRLALLPQDIARWQVSARDNITLGQGDGDDETVMAAAR
                     ASGADDVIACLSDGLDTNLAPSQWGGRDLSGGQWQRLAGARAFHRKDAPVLICDEPTSA
                     LDPRAEEAVYDRIRTLSEDRTVILITHRLGSTRAADRIIVLDGGRLLEEGTHDSLLAAD
                     GEYATLWRKQAQTYAGQPRG"
     misc_feature    9994..10009
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.59"
                     /tool="antismash"
     gene            complement(10001..10717)
                     /db_xref="GeneID:96294429"
                     /locus_tag="IE233_RS32130"
                     /old_locus_tag="GCM10010326_65470"
     CDS             complement(10001..10717)
                     /codon_start=1
                     /db_xref="GeneID:96294429"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="IE233_RS32130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65470"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_190028991.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6e-10,
                     bitscore: 32.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 1.1e-18, bitscore: 60.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRPGVYAAPSPDGIALMDIRAGRGQWRFLDPVGGRLWQKITDG
                     ATPARAIDDLTAYWHSKGADPAQVRTDLTALAGDLERADLLHHAASAAPPDRTEIRFAT
                     AVSVSSAQQLAGHIGLFAALLLLRLLPIRVAVAGARAATRLPGRAALPQEAEAAFAAVR
                     RAARLWPGRAACLEESLAAHFAAAFTGRRVRWVVGARFVPQGAHAWIEAGTVIIGQDES
                     DRVWPYFPALQVERSN"
     aSDomain        complement(10457..10708)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IE233_RS32130_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="9.30E-11"
                     /identifier="RREFam002.1"
                     /label="IE233_RS32130"
                     /locus_tag="IE233_RS32130"
                     /protein_end="87"
                     /protein_start="3"
                     /score="32.6"
                     /tool="antismash"
                     /translation="RPGVYAAPSPDGIALMDIRAGRGQWRFLDPVGGRLWQKITDGATP
                     ARAIDDLTAYWHSKGADPAQVRTDLTALAGDLERADLLH"
     gene            complement(10714..12495)
                     /db_xref="GeneID:96294430"
                     /locus_tag="IE233_RS32135"
                     /old_locus_tag="GCM10010326_65480"
     CDS             complement(10714..12495)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294430"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="IE233_RS32135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65480"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_161255923.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.4e-32, bitscore:
                     106.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIWATGFGPGEVRRGSVRRGQAELLAIGGCLATREEFSAARAAA
                     ECGAWTAAMRLPGSCLIVVRDRAGLRIAGDRAGTVTVYWIPVREGVLWATAAAPLAAFA
                     QAEPNPAVLLGAFTVRGVDVLAADSYFHAVRRVPPGNALILAPGRHPRTEALPVPSAVT
                     SFEEGVPAVRETIAAAVGRRATMAGSISSDLSGGVDSGTVTSLAAARGPLLAVTYTDAR
                     MGEQDDMRYAERIAHDHPQITHVTIDGTRAGVQHFDGLQDPAVLPFTDTPSFTLGLLAI
                     KAAQFGPATAHGSRAHLTGRGGDDVLDAVPAMVVDQYRAGHRREALRRTAAFARTRRAA
                     LWPVLGQAARTQRTPYSRALAALADTINAGSGRTAQSGPATSAAQMLTWCGSSAATTWL
                     TRAGRAAVADLVTARAQTAPSDTAPGALHERLALELMGDGHATFDQISRQQWGLPVHAP
                     LLDNLVVDACHAIPGYARTQPGDFKPLARAAFAGHVPDYLLHRRTKTAFTSSLFAGLRT
                     NAPALRRILGRSLLAQAGLLDVSKALASLGSAARGEPAPLAALHALIVTELWLATLPTA
                     RTMWWEQTTAHVQEVAP"
     misc_feature    12508..12519
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.65"
                     /tool="antismash"
     gene            complement(12728..12862)
                     /db_xref="GeneID:96295837"
                     /locus_tag="IE233_RS39635"
                     /old_locus_tag="GCM10010326_65490"
     CDS             complement(12728..12862)
                     /codon_start=1
                     /db_xref="GeneID:96295837"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS39635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_65490"
                     /product="hypothetical protein"
                     /protein_id="WP_267907212.1"
                     /transl_table=11
                     /translation="MDTTATTAETETYTAPVLSALGTVTGATLGSAGNDNADDTQYWQ"
     gene            complement(13050..14237)
                     /db_xref="GeneID:96294431"
                     /locus_tag="IE233_RS32140"
                     /old_locus_tag="GCM10010326_65500"
     CDS             complement(13050..14237)
                     /codon_start=1
                     /db_xref="GeneID:96294431"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639740.1"
                     /locus_tag="IE233_RS32140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65500"
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_229892993.1"
                     /transl_table=11
                     /translation="MAHATTRSASVIELAQELIRRPSRGGIDDYAPVLTVLEDWLTRGG
                     LPHRRLCDEAGQLVGLLVEIAGGRPGPWWTLDACVDTASFGDEEAWTFPPTAGDIVEGF
                     LRGRGAADSKLAASAFCHIAADLLPHAETLRGGLAVLLDVDEHTGGFGGARAYLSDPEA
                     AIPAGVMIGYPGLDDVVVGGRGLWRATLTVSAHSGHSGSSRSVLSAVSRAARLVQLLDT
                     ADLPGPPAVDAAFMLPPKLSVTAIRGGEGFSVAADRCELNVDVRTTPAFDAHDAETLVR
                     KAAAELDAELPGPTPTRVTPIASWPPFQLQPHEQPAAALIDAAASLGLAVRAKTAGPSN
                     IGNLLAGQAGGIPSTAGFGVPYEGLHGIDERASLAELPQVYAVYHRAVLDLLDAR"
     gene            complement(14249..15049)
                     /db_xref="GeneID:96294432"
                     /locus_tag="IE233_RS32145"
                     /old_locus_tag="GCM10010326_65510"
     CDS             complement(14249..15049)
                     /codon_start=1
                     /db_xref="GeneID:96294432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639741.1"
                     /locus_tag="IE233_RS32145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65510"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_229892994.1"
                     /transl_table=11
                     /translation="MTGSAMTDSALKRARLAQNLTQEEAADQLNEITGGATDASLLSAW
                     ESGRKRTGVRNRRALSQFYRERSEVLFAHQDGRVTASVLEATGTDVVVRVLTRYTDLVE
                     AMVEVVTGAREHLVVTGSRSREKAYLAAIETAVAQQPDLLHYRVLYGPPRHRGLSEHLV
                     RLLELRDPGERRNGVKTLHIGLVEPLEAMERYFVASETAAVVPLPSFHGAEGFDCGVLL
                     GREAAAGLVQYGREACASARPMEALEAVRALPVRHGATPGLGEA"
     misc_feature    complement(14387..14389)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15034..15048)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     misc_feature    15052..15067
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.18"
                     /tool="antismash"
     gene            complement(15491..16299)
                     /db_xref="GeneID:96294433"
                     /locus_tag="IE233_RS32150"
     CDS             complement(join(15491..15949,15952..16299))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294433"
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558177.1"
                     /locus_tag="IE233_RS32150"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_190028992.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MTSLAEHLVSDELWELFRRVVPETVVVRPQGGGRRRAGDRECLTA
                     IVFVATPGCSWRQLPPVFGPSWPTVYRRFARWSQQRVWARLHRVILDELGARGALDWSR
                     FAVDSVSVRALKGQLTGPNPTDRGKTGSKIHLIVDRAGLPVSVAISAANTHDSVALQPL
                     VMGIPPVRSPRGPRRRRPAKLHGGKGYDYPYLRRWLRARHITPRIARRGIENSQRLGRH
                     RWVVERTMSWLGGCRRLHRRYERKPEHFLAFTAIATSLINHRRLTN"
     misc_feature    16293..16309
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.53"
                     /tool="antismash"
     gene            complement(16339..16644)
                     /db_xref="GeneID:96294434"
                     /locus_tag="IE233_RS32155"
                     /old_locus_tag="GCM10010326_65540"
     CDS             complement(16339..16644)
                     /codon_start=1
                     /db_xref="GeneID:96294434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764025.1"
                     /locus_tag="IE233_RS32155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65540"
                     /product="hypothetical protein"
                     /protein_id="WP_190028993.1"
                     /transl_table=11
                     /translation="MNDTPQPASGGTAAEHYTGQVLAGPGGAMTDEVGVITGDLTLTTS
                     LEDDGLAHSRIQYTDADEWYTLTGSPQKPPARGLRTLHEQTLKAVRTGGAAEAPRT"
     gene            complement(16711..17400)
                     /db_xref="GeneID:96294435"
                     /locus_tag="IE233_RS32160"
                     /old_locus_tag="GCM10010326_65550"
     CDS             complement(16711..17400)
                     /codon_start=1
                     /db_xref="GeneID:96294435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490939.1"
                     /locus_tag="IE233_RS32160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65550"
                     /product="HNH endonuclease family protein"
                     /protein_id="WP_229892995.1"
                     /transl_table=11
                     /translation="MIILGAAGCSDTTDGKPAADGKPSPSVSASRPGAGGAQGAPGDVK
                     QLPGMPTVSVARAQLAGLKVAAVGSMAGYSREKFPHWASQGAKCDTREIVLERDGTGVT
                     KDAECKAVSGSWISRYDHLAFTSAAKMDIDHTVPLANAWRSGASTWTTEQRKAFANDLT
                     HPQLVAVSATSNRAKGDQSPDQWAPPAKDYWCAYAESWTTVKAAYQLTVTDAEKAKLAD
                     MLATCPA"
     misc_feature    complement(17389..17404)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.76"
                     /tool="antismash"
     misc_feature    complement(17394..17408)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            complement(17665..18039)
                     /db_xref="GeneID:96294436"
                     /locus_tag="IE233_RS32165"
                     /old_locus_tag="GCM10010326_65560"
     CDS             complement(17665..18039)
                     /codon_start=1
                     /db_xref="GeneID:96294436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007503737.1"
                     /locus_tag="IE233_RS32165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65560"
                     /product="hypothetical protein"
                     /protein_id="WP_190029060.1"
                     /transl_table=11
                     /translation="MSRNPLQESVQRGWDGSWYRVSTDAFEASFLPSPDEELDSVCNVE
                     VLVKLKDGSRWSATVFTLAEVERPMKTWAGSGEALEGRYFWASDGLIVRDPGIDSMADV
                     IAGLIEEEDFRAVLQRRADD"
     misc_feature    complement(17686..17688)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18164..19324)
                     /db_xref="GeneID:96294437"
                     /locus_tag="IE233_RS32170"
                     /old_locus_tag="GCM10010326_65570"
     CDS             complement(18164..19324)
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036297 - interstrand cross-link repair
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294437"
                     /inference="COORDINATES: protein motif:HMM:NF017984.5"
                     /locus_tag="IE233_RS32170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65570"
                     /product="DNA glycosylase AlkZ-like family protein"
                     /protein_id="WP_190028995.1"
                     /transl_table=11
                     /translation="MSATPRPGLELSLAHARSIAVAAAFPPGDRLDVPSTLGHLHAVQL
                     DSISVLARAHQLTLATRIPHTTTRDVDAALNSASPPTAFVYPAHALSLVPLTDWPLWAF
                     RRRHTRTRPQYPDPGQRAALLARIRADGPLPLRSLRTEQPTTTGWGWGPTKTALEFMVW
                     AGDLACTRYTAGQRLFDLPERCIPHPLLGDDLDDDTCLTRLLEHAAKTLGVGTVDDFAD
                     YLRIRPASAARLLPDTALTPVAVQGWSSAWAHPSALARPEAARREPVFLGPFDNLIWHR
                     PRVQRLFGFTQVFEAYKPAARREHGYYVCPLLADGQLVARADLASTSAGLTIHQASFEP
                     HAGPEAAARFASACHTLATTTGTDRITVQADAADPHTSAALRKALR"
     gene            complement(19338..20642)
                     /db_xref="GeneID:96294438"
                     /locus_tag="IE233_RS32175"
                     /old_locus_tag="GCM10010326_65580"
     CDS             complement(19338..20642)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294438"
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007830570.1"
                     /locus_tag="IE233_RS32175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65580"
                     /product="MFS transporter"
                     /protein_id="WP_229892996.1"
                     /transl_table=11
                     /translation="MTGRPVRGLLTIAFLTRTTAATLPILLLLALADAHGYARAATVGG
                     TYTLVLALCAPLRGRLLDRCGPRMLLAMACATTVLLALVAASIHFTWPWPTTLPLVIAA
                     TLTSPPLNAALRSSWRRLATGDAQLKAVHSADSVLEEAGFVLAPLAAGTVLVLLGPRHG
                     YETAAACFVAVMALYLAAARRHHLTPTHTPAPATTVRPRRRRWLGPLALPGMPAILLPL
                     LVMGALFGGTGILVPAYTQHQHATAWLGPLLAATSTGGVLGGIAYAALPWRSDLWRKYR
                     ILTLGFTTPALLLFLARPLWLLAALLLIAGLFVTPLFINAFLLTDATATDETRIEANTW
                     IGATADVANGIMATIIGTLVQAQKWNTALFTLTCCAATGAAATLIQMSRHRSRPVVPGA
                     GERQPADTATGLPPRAVVVRPAPSPAAQAVSEQNP"
     gene            complement(20711..21472)
                     /db_xref="GeneID:96294439"
                     /locus_tag="IE233_RS32180"
                     /old_locus_tag="GCM10010326_65590"
     CDS             complement(20711..21472)
                     /codon_start=1
                     /db_xref="GeneID:96294439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007830571.1"
                     /locus_tag="IE233_RS32180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_65590"
                     /product="hypothetical protein"
                     /protein_id="WP_190028996.1"
                     /transl_table=11
                     /translation="MAEVTFHPLHPWALLPEKPKADRAGARAERDAYQDSFRYLRIPRL
                     PADCPPWVLGQELGWSLRSPLTLTMRPLEDIGLAVPDAEDPQQVGRRLGGQRMFQRGKD
                     WIATGDASWLHLGDYRTPTGGWEGMFIPNGQGTVEWRLGFAAQIPPGTFLMVMPPPIPC
                     APGLGVPLGVIPAKAVNAMADRGGMSIAVQIDHPVSIHRGQEIARIVLLHPDSLRATAH
                     STPTASATTPPRAAAEVHVPPEAAHAAEETR"
     misc_feature    21852..21867
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.52"
                     /tool="antismash"
     misc_feature    22195..22209
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.37"
                     /tool="antismash"
ORIGIN
        1 ccgggccggc gggcacgtag gcctgccccg ccttgatggt gtacttcgtc agcgctttgt
       61 cggtgtccgt ctggacgggc acctgggtgc ccgtgtagtc ggcggtccgc gggtaggccc
      121 tgccgtacac cgggatggag gcgaccccgg ccttcggtgt cacgaccggc tgggccgcgg
      181 tgccgacggg ggcggtgcgc tggccgccgg gattatagaa ccagccctgc ttgccgccgt
      241 accagatcgc cgtccagtcg cccttgaccg cggcgaccac gtagcggcca ccggtgaccg
      301 ccttggcggc ccagtccggg ccctgggtgc tgcccgcggc gccaccgcgc agatacgggt
      361 ccgcgatcat cggggagctg gtggaggcgt cggagtagag gtacaggaag ttcgccgggt
      421 gcggtgcctg cgtcgtgcag ggaccgggcg agcaggacac gatgaccggc tggttggccg
      481 tggtgaacgg cgggacgacg gtgatctcct ggcccgccgc gaccgggctg cccgcaccgc
      541 cgtcaccggt gggcgcgccc atcaagccga agtagtggtt ccagtcccag tacgggcccg
      601 ggtcccagtg catcccggcg acgttggcgt cgatcgggcc gggtacctcg tcgtgaccga
      661 tgatgtgctc gcggtccagc ggaatgccga accgggcggc caggtatttc accagcgccg
      721 ccgacgactc gtactgggtc tcgctgtacc agctgcccgc cttgatggcg tagccctcgt
      781 gctcgacgcc gatcgagtgc atgttgaggg tcttgttgcc cgcgtgccag gccgtgtcct
      841 tggtgggaac gagctgggtg accaggccgt ccgaggcacg gaccatgtag tgcgcgctcg
      901 cggacttcgt cgggtcctgg aagacgctca gcgagctgtc gtagccgccc tcggtgtcgt
      961 ggataacgat gtagcggatg tcgacgccgt cggcgggacg gttggtgacg tcgtaattgc
     1021 cgtagtccgc caggtccttg ctgttctgtt tgaacgcggc gggccggaag tcgcagttca
     1081 gccccgccgg gcactcgggt gtcggaacgg ccgccgtgct ggcgaacgtc gcggcgagct
     1141 tcatgcgcgt cggcggcttg accggggtga ccgaccggtc ggcgggcagg gtgacccgct
     1201 gcccgtccgc cgtgacccgg ctgctgcccc ggttgatggt ccggaagacc cgctgcgcga
     1261 agagttcggc gcccttggcg tccggggcct ggctataccg tgcgactgcc gcgtaccact
     1321 gccccgcgtc ctcgggcagg gaaccggtgg cttccttctc gtacgcggcc agcagcgccg
     1381 cgccgccccg cacgctctcc gcgcggtcgg tgcgcagcgc gtcggacgac tcacccgtca
     1441 gttcggctgc cgtgtccagt gtgtggagcc ggggatcagc ggtgtccacc tgggtgtcgc
     1501 cggtcttcag ggccctggcc ggattgaact tcttcatcct ggccgggtcg ccgctcatgt
     1561 tcagatgcga cagccgatcc gcccgggtcg gctcctccac gtcctgggcc gtcacccggg
     1621 tcaggcccat gacgttgtag ttcccggccg tgctgggctg cccctggtgc gtctcccacc
     1681 gggtcaggtg gtaggagacg ctcatcaata cgctctgggg aacgtggaat tcccgcgccg
     1741 cgtccgcgaa ctcccgctgc agtcccgcgg ccgggtccgg cgcggcctcc gcgctgccgg
     1801 acggacccgc cagtgcgaac gttccgactg ccgccacgga tcccgcgatg agcgtcgccg
     1861 ctatgccgat cggcagaaat ctccccgacc ggcggtgtgt acgagtcaac gacctgcctc
     1921 aatcttctgg cgcatcacag cgccccctat gtctcttgtg tccggagctg cgaaagggat
     1981 cgcaccgccc ccgaggactg ctgtcgtaca gcaggcgggc cctgcgggag gagaccaagg
     2041 ctcagccccc ttcccgtctc ggctgctcag ccggtgatgg cgaccggggc gtcccacgcg
     2101 tcgcggtcga cggtgatggt gtaaccgccg cgggtttcct tgctgttgac catgaactgg
     2161 tggccgcggc tgtggtcggt gtagagcttg ctcgcccagg gccagtcgct ggttgtcgtg
     2221 ttggcgttgt cccacttcgc gtaccagaga ttgcccggca ggtcggtgcg gttggcggcg
     2281 gtggcgacgg cgtgggcgct ggtggtgctg aagccgtagt agccggcgcg gtacgtcttg
     2341 gcgcgcaggg ttttggtgaa ggcgcggacg taggcgagga ccgcgttgtt gcacgacgtg
     2401 ttcttgatgt cgtacggctc catgtccagg tagatcgcgc tgcccggctt catgccgagc
     2461 gcggcggcct tggccaccgc gtccgcgccg tcggacgcac cgagggatga agcgctggcg
     2521 gcggtcatct tctcggggct cttgccggtc tggcaggccg gctgagcacc cacgtagagg
     2581 gggatcagtt tccagccctg ggcggtgacc gtcttcaccc aggacgcggt caggttcggc
     2641 tgggaacagc cacggttctt cccgccgacg tagatggcgg ccgcgccata aggtccgggc
     2701 ttccaagcct tcatcgcggc ggcggaagga gccgcgcagg tgtcgaaggc gagaccggtg
     2761 aacgtcttct gtgccggcca cgccggtgcg gccgatgcgc tctgcgcgat caggccgccc
     2821 gtcgcggcga cggccacacc ggccacgccc cacccgatgt agcggtttct cttcgagaga
     2881 cggtgcgcag gcttgcgcga cttgtcggac atgtagtccc caccccttgt cctgtttgtg
     2941 cggtttgctt ctgctgatgg tgcgcggcaa ttgccgctga tgttcgtttg acgtaggcgc
     3001 tgatgccacg tcaagcgccg cccccgggtg catcagagaa tacctagaaa gttcagtgca
     3061 cttgttcccc gaccccaccc ggcggagcag ctggaatcgg tgggcgttcg cgctccccag
     3121 ggcagccatg ggcaccccgc aagacgacat aggcccctgc ggccggcaag ggctgcaggg
     3181 gcctgcgctg cgcttgtgga agtcagttgc cagtcaactt gggcaacggc tccgttgcgg
     3241 cgggatgagg gccctggaac tcactccagg gccctcactg tgacgagacg aaatgagggc
     3301 tacctcttac gcgccttact caccagaaat gccaccccca cgatgatgat caagatgatc
     3361 gcaattatcc agaaagccgg ggtcccgtga ccgactccct tggctagaaa aagtccgtga
     3421 gtcattatgg cctccctggt cttgttgctg gtaccaccga ttaattgagt acgctgcttg
     3481 cggccttttc gcccagctct ccagccccat agccgatccc gaagcaggtg gctccgacag
     3541 ctagcccacc cacacccgca gtgggcgcgc tgaaggcagt tgcgactgcg ccacacccgg
     3601 cctcagcagc ggcgcccgct gccatgccga ctcctgtagc cagggcatct ttgtagttgc
     3661 cctcgctgat gtccttggcc atgctgccga cgtcatatat gtcgaacccc ttacctacgg
     3721 catcgaaaaa ggacaggccg ttcgggtccg tcttgttgat gggtcgccgg cggcgtaggc
     3781 gtacaggttg ctttccttgc cggaggggtc gggctgggtg aagcggccga gttgggggtc
     3841 gtagtagcgg gcgcccatct tgtacaggcc tgacgggtcg aggtaggtgc cggtgtagcg
     3901 gtatggctgg ttggtgccgc tggtggtgcg ggcttcaccg tagaggccgt agctgtaggt
     3961 cgcggtgcgc ttgccggagg cgtcgaccag accgatgacg ctgccctgga cgtcggtcag
     4021 gtagtactgg ctcgctccgc cgctggtcat ggctgtcagc gcgcccgagg ccttccggac
     4081 gaaaccggtc gtgtcctcgc gcgtcatgcc ggtcgcggcg ttggtgaagg tccagctggc
     4141 cgtgggtcct cggccgcgcc ggctgtgtcg tggtgctgtg ggtggagggt gtagttccag
     4201 tcgccgtgga agcggtgccg gtgcatgggc agtgagtcga tgtctgtgtc gctgaccttg
     4261 atgccggtgt cgtaggtgcc cgggtcgagt tcggcatgga ctgtcaggcc ggtgtgggtg
     4321 gtggttgcgt tgatgctgtt cacgatgacg tcgtggctgg tcaaaggtct gccccgccag
     4381 ttcatggaga tgtgggagaa cagccgatgc tcgatcttgt tccacttcga ggtccccggc
     4441 ggcatgtggc agaccgtgat ctccaggccc gtctcacgcg ccagggcggc gagttcggtc
     4501 ttccaggcgc gggggcggta tccgttggag ccacccgcgt ctgcagtgat cagcagccgg
     4561 tcggcctgag ggtagtcgtg gccggcacgg gcctgccacc agcgtcggat cgaggcgacg
     4621 gcgaaagccg cggtgtcgtg gtcggtgccg acgctgaccc agccggagtt cgcggcgacg
     4681 tcgtagatcc cgtacgggat cgccttgccc ggtccctgcc ggtccaggaa gtcatgggtc
     4741 ttgacctggg ccggagctcc cttcggttcc cactcacggc ccccgttctt gtaggggccg
     4801 accagttcct tcttctttgt atccacgctg atcaccgggt cggcggcagc gatgtgctcc
     4861 ttgacctgct cgttgatgta gtggaactgg gcatcccggt cgggatgctg ggcgccctcg
     4921 agggtcttgg cgttggcctg gaggctgaat ccttcctccc tcagcaggtc ggcgacggta
     4981 tccgccgaga tgcggtggcc ctgcctggtg aggtggtcgg cgagtgcgcg ggtggacttc
     5041 gtcgtccatc gcagtggcga catcggatcc ccacacatgt cgggttcgac cagcgccaac
     5101 aaagcgggcc gcagtcctgg atccacctct gctgcccgct tgcgcccgcc gcctggacgg
     5161 cggactcggc ccaatggttc cgcccccgcc tccagctcgt ccacgccttt acggacggtc
     5221 gcctcgctgg cctcggccac ctgggcgact gcccggatcc cgccgtgccc cagaattcgg
     5281 gcttcggccc ccatcagcag acgtcgctgc cgctcgtcca ggtgaggaaa caacaccgcg
     5341 aacttcagag tgagttgatc acggacctcg tcggatatgc gcataccaca ccaacgaccc
     5401 gaaccacgga aagcaacacc ttgattctct gcaagtccta agaccgtgtc ctacatggtc
     5461 agtttgagga accgcttgta gcagcagagg gcggatgcca gcccgagaaa ggccaggtag
     5521 ttgcctggtt tccgctcgta acggtggttg agacggcggt agccggtcag ccaggacatg
     5581 gtgcgttcga tgacccacct ccgtcggccg agtcgctcgc tggagtcgat gcccttgcgg
     5641 gcgatgcgga cgccgatgcg tttgccccat agccatcgcc gcaggtgagg gatgtcgtac
     5701 gccttgtctg catggaggcg cacgggtttg gagtcggccg cgtgggattc gtgtcccatg
     5761 tggaaatggg acagcatcgg cttcagagcg agactgtcgt gggtgttggc cgcggagagc
     5821 ccgacccgta agggcagtcc gttcgcgtcg gacaggacat gcatcttgga accgggctta
     5881 ccccggtcca cggggctcgg acctgtgtgt tcgccccctt tttagccctc acgtgtgcgg
     5941 agtcgaggac tgcacgggac aggtcgacca agtcctgctc gtccagaagt tggagaacct
     6001 tctgatgcag tcggccccag accccggcgc gggaccagat ggcgaagcgg cggtgcacag
     6061 tcgacttcga cgctccgaag catggcggta acgcccgcca tgcacagcca ctgacgagca
     6121 cgtagatgat cgcggcaaac accgcctcat cgtcgatgtt cgcgacccca ccaccctgcg
     6181 gacgcacccg cgccggcggc agcaacggcc ttgccaactc ccacaagccg tccggaacga
     6241 tccatcccca ccgtccactc cccatgccca gcataaccgt caactgacca tgtaggacac
     6301 ggtctaaggc gggcgacagc tccggggtcg cgcccccgct cgcggcatgg ttctcccggc
     6361 gcggcgcgcg cctctctctc cccgggggac gcgctacgcg gatccggggg ccgccccgat
     6421 gcgctccgcg accaaggcgg tccgcgcgtc cttgagccgc gcgatgcgcg cgtccgcctc
     6481 ggcgatgagc gggtccacgg accctccacc gccgtcgctc gcatggatgt cgaggaagaa
     6541 gatctcgccg tcctgggggt tgttggtcaa gaacccctgg acgtccgtca tctgcgcctc
     6601 cttcaccgag gcgagttgac cgtgcagccg gtgcaggcga ttcaggtccg tgatctcgtt
     6661 gatcagcctc ttgaagatct tctcgtgccc gggcttcgac agctggaaga aggtgccgct
     6721 caccttcttc atgcggatga cgtacgcggg cacagaggat gggccatcgg tgtaggtcgt
     6781 ctccatgccc gtccagttcg gcaccggaac tcccgctgct gcggcctccc ttgtgcgctt
     6841 cgccacggtc cgcccctgcg gcagactcgt gaacaccttg tacacgtagt cccgttcgac
     6901 gtagacgatg gcctcacggc tggtgacccg attccccagc tgtacggtcg cgtcgccctc
     6961 cgtgatctga gcccgctgga tcggcgcttc ccgcgtgttc acgctcgtgc tcgccggcgt
     7021 ggaactgccc gccccgtgcg cttcccggac gcggcgctgc gtcggcacgg gctcggccat
     7081 cacccgcgcg gcgttggcct ccgctgcgcg ctcgaaccgg tcggccggat cggagacgcg
     7141 caacccgctg ccgttgtcgg tgcccgcgac gggcccttgg cgctgctgga tgacgtgggt
     7201 gagttcatgg gcgagggtga gcttgtcacc cccgccgtct ccgatgacca catggctgcc
     7261 ggaagtgtag gcgcgggcgc cgacctccgc cgcggacgcc tgggccgcgc ggtccgtgtg
     7321 gatccggacg tccgagaagt ccgcgccgag ccgggactcc atttcagcac gggtggagtc
     7381 gtcgagcggt cggccgctgg tccgcaacac ctcgtgagcg gcggaacgtt gcacgacgga
     7441 cgcctcggct ccgtgtccgc agccggcgtt gtgctggtgc tgctcctgcg cccaggggtg
     7501 gccggccgcc cggagcatct gtacgacggc ggcgttgccc gcggccgcct ggagcgcgaa
     7561 gggggccgct tgcgcactgc caccgtgcgc ccttgtgctg gcgggcgtac gggcgggccg
     7621 cttcccgtcc ggggtgcggg cttgctcgtt ggcgtacatc gggtcctttc gcgaaccgtg
     7681 acacggtctg tatgcggagc gccgggccca ccatcagcaa ggaagccccg ctccacgagg
     7741 agcggggcaa gtgtttccgc ggtgggcaac gcttcgctaa tgccacgtcg gtccggcgtt
     7801 agcgcctgct cggccccgca gtcccgggac cgttgctcga cccgtacttg acggcctggg
     7861 ccaaggccat gagcgggcgg gagcagtccc agcgcggcat gaagacggtg accagcgtag
     7921 agccctcgcg gtcgggctct cgcctggtga acggagtggc ccggcccgcc gcaggttcac
     7981 cctcggggct ggccggcgta ggtctgcgcc tgctttcgcc acagggtggc gtactcgccg
     8041 tcggcggcga ggagggagtc gtgggtgccc tcttccagga ggcgtccgcc gtccaggacg
     8101 atgatgcggt ctgcggcgcg ggtggagccg aggcggtggg tgatcaggat gacggtgcgg
     8161 tcctcgctca gcgtgcggat gcggtcgtag acggcttcct ccgcgcgggg gtcgagggcg
     8221 gatgtcggct cgtcgcagat gaggacgggt gcgtccttgc gatggaaggc ccgggcgccg
     8281 gccaggcgct gccattgccc gccggacagg tcgcgtccgc cccactggga gggggcgagg
     8341 ttggtgtcga ggccgtcgga aaggcaggcg atgacgtcgt cggctccgga ggcgcgagct
     8401 gcggccatca cggtctcgtc gtcaccgtcg ccctggccga gggtgatgtt gtcgcgggcg
     8461 gatacctgcc agcgggcgat gtcctgtggc agcagggcga gacgcgacca cacctgttcg
     8521 gggtcggctc cggccaggtc cacgtcgtcc caggtgacgg tgccggtcgt gggggtgtag
     8581 aggccagcga ggagtttggc gagagtggac ttgcccgcgc cgttcgcgcc gacgatcgcc
     8641 aggacctcgc cgcggcgcac ggtgacactg atgtcctcca gcacgggcag cgcgctgccg
     8701 gggtagcgga aggtgacgtt gcgcgcggcg atgacggccg ggcggtcggg taccggaacg
     8761 ggtgtggcgg gcagctggga gcggtgttcg gcgtcggtga ggaaggtgga ccagtcgccg
     8821 aggtagaggc cggtcttgta ggtggagttg atgccggtga ccagttggcc caggagcagg
     8881 cggcaggtct ggacggcgat gaacgcggtg cccgccgcgg cagctgggat gtggccgtcg
     8941 agcacgaggg cgagcagcgt gccgtagacg acgagggcgg cgcctccggc catggtgtcg
     9001 ccgaagagct ggtagcgggc ggtggtgcgg ccgatgcggg cggcgtgcgc ggtgagccgg
     9061 tcggtgacgg tggtgaactg gccgaggagc cagctgcgca tggtgttggc ccgcacgtcc
     9121 agggcggtgg cgcggccggc ggtgcagtag atgagattgt ggcgcaggcg gcggtcggag
     9181 agggtgtgcc gctcggcgag gtgggctgcg cgcgcgccgc ggacggcggc tgcgccccgg
     9241 gggatcacgg cgagcagcag gagcgggagc agcagggggt ggagggctgt gaggatgccg
     9301 gcggcggcga gcaggccgag gaatgctgcg gtcagggcgg tgagggcgtc gatcatcaag
     9361 tgggcgtcct tggaggcccg gttggcggct tcgctgtggt cgcaccaggc cgggtcgtca
     9421 taggcggcga gcgggacgcg ggtggcggcg ttcaggtagc gcagctcggc gatcgcgtcc
     9481 acgcgggggc cgatgcgggc ggtgacggcc agggttgtcg cggcgaccag ggagcggccg
     9541 acggcggcgc cggtgatcag ggcgagtgag ggcagcgccg tctggatacg ctcctcggtc
     9601 ggcccggtgg agagcagcgg ggcgagggcc ccgcgggtgg cgtagaggcc gcccgcggtg
     9661 atgacgccgg tggccagctg cagaacggcg gtgagcagga cggcgcggcg gtcggcgtcc
     9721 caggccaggc ggagcgcggt cgcggccagg gcgggcaggc gccgggcgat ggtggtgaag
     9781 tcgtcggcga gggcgttgtc gtggcgctcg gcgctgaccg tgtactgcgg gatgggctcc
     9841 ccgccggtgg ggcggcggcg cggccacggc agccgaagcc gtcgccccgg ggcggaggtt
     9901 gtgagggtct cgcgggtggc gctgcggtgc gcggtgtctg tcacatcctg ggcaacgcct
     9961 cacccatacg ggtggttgtg gtggcgaaag gtggcgaatt tcagttcgag cgttccacct
    10021 ggagagcggg aaagtagggc cagacgcggt cgctctcgtc ctgcccgatg atcacggtgc
    10081 cagcttcgat ccaggcgtgg gccccttgag ggacgaagcg ggctccgacc acccagcgca
    10141 cacggcgtcc ggtgaacgcg gccgcgaagt gcgcagccag ggattcctcc aggcaggcgg
    10201 cgcggccggg ccagagacgg gcggcccgac gtacggcggc gaaggcggcc tccgcctctt
    10261 ggggcagggc ggcgcgtcct ggcagacggg tcgccgcgcg ggcgccggcg acggcgacgc
    10321 ggatgggcag gaggcggagc aggaggagcg cggcgaacag cccaatgtgc ccggccagtt
    10381 gctgggcgga actgacggag acagcagtgg cgaaccggat ttcggtgcgg tcgggcgggg
    10441 cggcggaggc cgcgtggtga aggaggtcgg cgcgttcgag gtcgccggcg agggcggtga
    10501 ggtcggtgcg gacctgggcg gggtcggcgc ccttgctgtg ccagtaggcg gtgaggtcgt
    10561 cgatggccct ggccggggtc gcgccgtcgg tgattttctg ccacagacgg ccgccgaccg
    10621 gatcgaggaa gcgccactgg ccgcgcccgg cgcggatgtc catcaacgcg atgccgtcgg
    10681 ggctgggggc ggcgtagacg ccgggacgcg tactcacggg gcgacctcct gtacgtgggc
    10741 ggtggtctgc tcccaccaca tggtgcgggc ggtgggcagc gtggcgagcc acagctcggt
    10801 gacgatcagg gcgtgcagcg cggccagggg cgcgggttcg ccacgtgctg cgctgccgag
    10861 ggaagccaat gccttcgata cgtcgagcag gccggcctgg gccaagaggg agcggccgag
    10921 gatgcggcgc agggcgggcg cgttggtgcg cagtccggcg aacaggctgc tggtgaaggc
    10981 ggtcttggtg cgcctgtgca gcagatagtc ggggacgtgg ccggcgaagg cggcacgggc
    11041 gaggggcttg aagtcgccgg gctgggtgcg ggcgtagccg ggaatcgcgt ggcaggcgtc
    11101 caccacaagg ttgtccagaa gcggggcgtg gacgggcagg ccccactgct ggcggctgat
    11161 ctggtcgaag gtggcgtggc catcgcccat cagctccagg gcgagccgct cgtggagggc
    11221 gccgggggca gtgtccgacg gggcggtctg ggcgcgggcg gtgaccaggt cggcgaccgc
    11281 cgcccggccg gcgcgggtga gccaggttgt ggcggcgctg ctcccgcacc aggtgagcat
    11341 ctgggcggcc gatgttgcgg gaccggactg ggcggtgcgc ccggagccgg cgttgatcgt
    11401 gtccgccagg gcggcgaggg cccgagagta gggggtgcgc tgcgtgcggg cggcctgccc
    11461 gagcaccggc cacagtgcgg cgcggcgggt gcgggcgaac gccgcggtac ggcgcagcgc
    11521 ctccctgcga tgcccggccc gatactggtc gacgaccatg gccggaacgg cgtccagaac
    11581 atcgtcgccc ccgcggcccg tcaggtgtgc acgcgatccg tgggcggtgg ccgggccgaa
    11641 ctgcgcggcc ttgatggcca gcaggccgag cgtgaacgag ggcgtgtcgg tgaacggcag
    11701 gacagccggg tcctgaaggc cgtcgaagtg ctgcacgccg gcccgggtgc cgtcgatcgt
    11761 cacatgggtg atctgcgggt ggtcgtgcgc gatgcgctcg gcgtagcgca tgtcgtcctg
    11821 ctcgcccatc cgcgcgtcgg tgtaggtgac ggccagcagc ggcccacggg cggcggccag
    11881 gctagtgacg gtgccgctgt cgacgccgcc ggagagatcc gaggagatcg agcctgccat
    11941 ggtggcccgc cggccgacgg cagcggcgat ggtctcgcgc accgccggga cgccttcctc
    12001 gaaagacgtc acggccgaag gcaccggcag cgcttcggtc cgcggatgcc gaccgggcgc
    12061 caggatgagg gcgttgccgg gcggcacgcg gcgcaccgcg tggaagtagc tgtcggcggc
    12121 caggacgtcg acgccgcgca ccgtgaacgc gcccagcaga acagccgggt tgggctcggc
    12181 ctgcgcgaac gcggccaaag gggcggccgc cgtcgcccac aacacgcctt cgcgaaccgg
    12241 gatccagtac acggtcaccg tcccggcccg gtcaccggcg atacgcagcc cggcacggtc
    12301 gcgcaccacg atgaggcagg agccgggaag acgcatcgcg gcggtccagg ccccgcactc
    12361 ggcggccgcg cgtgccgcgg agaactcctc gcgggtagcc aagcagcccc cgatcgccag
    12421 gagctcggcc tggccgcggc ggaccgagcc gcggcggacc tcgcccggac cgaacccggt
    12481 cgcccagatc cgcaccgcgc cgtcggcgaa aacgtcttgg gcttcccgag ggcgccaatc
    12541 gctcccggcc caactaccgc gccccgtatc gactgttccg gcaatgaacc gcatggtggc
    12601 caccccgatc cgttcgttcg tgtactggtc tgccgcgttt caccgaacga gcgcccggct
    12661 cgccggccat cggccgacgc tccgggcgct cgctcacccg ctcacacccc cgattcgggg
    12721 tgccgcacta ctgccagtac tgggtgtcgt ccgcgttgtc gttgcccgcg gagccgaggg
    12781 tggcgccggt gacggtgccc agcgcgctca gcacgggcgc ggtgtaggtc tcggtctcgg
    12841 cggtcgtggc ggtggtgtcc atggagtacc tccggtagtc gtcgcgcttc ggatgcccgc
    12901 cggccgtccg gggtgtctgg caactcccgt acggcctctc gaactcctct atgacaccgc
    12961 gcgccaaccc cgcccgacag agcagaactt gggcacttcg taggacccga cctggaacgg
    13021 aactggtatt cgactgggag gtgccgaggt cagcgtgcgt ccaggaggtc gaggacagct
    13081 cggtggtaga ccgcgtacac ctgcgggagt tcggcgagac tggctcgctc gtcaatcccg
    13141 tgcaggccct cgtagggaac gccgaagccg gcggtcgacg ggatgccccc ggcttgtcct
    13201 gccagcaggt tgccgatgtt ggacgggccg gcggtcttgg cccgcaccgc caagcccaag
    13261 gaggctgcag cgtctatcag ggcggcggcg ggctgctcgt gcggctgcaa ctggaagggc
    13321 ggccagctgg cgatgggtgt gacccgggtg ggtgtgggac cgggcagctc ggcgtcgagc
    13381 tctgcggcgg ccttgcggac cagcgtctcg gcgtcgtggg cgtcgaaggc cggggtcgtg
    13441 cgcacgtcga cgttcagctc gcaccggtcc gcggccacgg agaagccctc gcccccacgg
    13501 atcgcggtta ccgacaactt cggcggcagc atgaacgccg cgtccaccgc cggagggccc
    13561 ggcagatcgg cggtgtccag gagctggacc agtcgcgcgg cacgggagac ggcactcaga
    13621 acgctccggc tggagccgga gtgccccgag tgcgcggaca ccgtgagggt cgcgcgccac
    13681 aggccccggc cgccgacaac gacgtcgtcc aagccggggt agccgatcat cacgcccgcc
    13741 gggatggcgg cctccgggtc cgataggtac gcgcgggctc cgccgaagcc gccggtatgt
    13801 tcgtcgacgt ccaggaggac cgccagacca ccacgcagcg tttcggcgtg aggcagcagg
    13861 tcggcggcga tgtgacagaa cgctgaggcg gcgagcttgg agtcggcagc cccccggccc
    13921 cgcagaaacc cctcgacgat gtctccggcc gtcggcggga acgtccacgc ttcctcgtcg
    13981 ccgaaggagg cggtatccac gcaggcgtcc agggtccacc acggacccgg ccgaccgccg
    14041 gcgatctcga ccagcagccc caccagttgg cccgcctcgt cgcacaggcg ccggtgcggc
    14101 aacccgcccc tggtcagcca gtcctccagg acggtcagga ccggcgcgta gtcgtcgatt
    14161 cctccgcggc tgggcctgcg gatcagctcc tgggccagct cgatcacgga tgccgagcgc
    14221 gtagtggcat gggccaccaa gtccttcttc acgcttctcc cagtcctggc gttgcgccgt
    14281 gccggaccgg cagcgcgcga acggcctcca acgcttccat cggccgcgcg gacgcgcacg
    14341 cctcccgccc atactgcacc agtcccgccg cggcctcgcg acccaataag accccgcagt
    14401 cgaacccctc ggccccgtgg aagctcggca gcggcaccac ggccgcggtc tccgacgcca
    14461 cgaagtagcg ttccatcgct tccagcggct cgacgagccc gatgtggagc gtcttgacgc
    14521 cgttgcggcg ctcgccgggg tcacgcagct ccaacagccg caccaggtgc tcggacaacc
    14581 cgcggtgacg cggcggcccg tacagcaccc ggtagtgcaa caggtcgggc tgctgcgcca
    14641 cggctgtctc gatcgccgcc aagtacgcct tctcccgact gcgagatccc gtgaccacca
    14701 ggtgttcacg cgcaccggtc acgacctcga ccatggcctc gacgagatcg gtgtaccgag
    14761 tgagcacccg cacgaccacg tcggtgcccg tggcctccag aacactggcg gtaacacgcc
    14821 cgtcctggtg ggcgaagagc acctcggagc gttcccggta gaactggctc aacgcccggc
    14881 gattcctcac ccccgtgcgc ttacgccccg actcccacgc actgagcagg ctcgcgtccg
    14941 tcgcgccgcc cgtgatctcg ttcagctggt cagcagcctc ctcttgcgtc aggttctgag
    15001 ccagccgagc acgcttgagc gccgaatccg tcatggccga tccggtcacc gatcccccaa
    15061 gggtgtacgt ggccggcagc agaccgccgg cgcttggcca tcaccgcgtg ccgagttgcc
    15121 gagtcgcggc tacgccgtgc cacgggtcgc agctctgccc cgatcgtgtt gtgcccacgc
    15181 tcgggcctgg accttctccc cggacgcgac gacgagaaga agcgctcatc gtgttcacta
    15241 ctaccgcctg gatccgccga cggtccccgc ctggtgagcc gctcctgccc tgcacagttg
    15301 cccccatgcc gatccgtccc gtcactgagc gatgctgcca cccagacgcg acaggcgaca
    15361 gtccccctgt ccagcgcgat gcgcgcttgc cggatgcccg gggagcttcg acgtaccccc
    15421 ggcgcgaccg gcgcactgtg cgcgagtgca tcaatgaggg gagggatggg tcgcctcatt
    15481 agacgacgtt tcagttggtg agtcggcggt ggttgatgag gctggtggcg atggcggtga
    15541 aggccaggaa gtgctcaggc ttgcgttcgt agcgtcggtg caggcgtcgg catccgccga
    15601 gccaggacat ggtgcgctcg accacccagc ggtgtcggcc caggcgttgt gagttctcga
    15661 tgccgcggcg ggcgatgcga ggggtgatgt gccgtgcgcg gagccatcgg cgcaggtagg
    15721 ggtagtcgta gcccttgccg ccgtgcagtt tggcgggccg gcggcggcgt ggtccgcgcg
    15781 ggctgcggac cggtgggatc cccatgacca gcggttgcag ggccacgctg tcatgggtgt
    15841 tggccgcaga gatggcgaca gagacgggca ggccggcccg gtcgacgatg aggtgaattt
    15901 tcgatcccgt cttgccgcgg tcggtcggat tcggtccggt cagctgcccc ctttgagtgc
    15961 acggacactg acggagtcaa cggcgaaccg tgaccagtcc agggcgcccc gggcaccgag
    16021 ttcgtcgagg atgacgcggt gcagacgggc ccagacacgc tgctgactcc aacgcgcgaa
    16081 acgccggtag acggtgggcc aggatggtcc gaacaccggc ggcaactgcc gccaggaaca
    16141 gcccggcgtg gccacgaaca cgatcgcggt cagacactca cggtccccgg cccgccgacg
    16201 gcccccgccc tgaggacgca ccaccaccgt ctccggcacc acccgccgaa acaactccca
    16261 caactcatcc gagaccagat gctcagcaag actcgtcata ccaacacaac gaccagcccc
    16321 accaaaggaa acttcctctt atgtgcgggg agcttcggct gcgccgccgg tgcggacggc
    16381 tttgagtgtc tgttcgtgca gagtgcggag tcctctggct ggtggtttct gggggctgcc
    16441 ggtcagggtg taccactcgt ccgcgtctgt gtactggatg cgggagtggg ccaggccgtc
    16501 gtcttcgagg ctggtggtga gggtgaggtc gccggtgatg acgccgacct cgtcggtcat
    16561 cgcaccaccg gggccggcga ggacctgtcc ggtgtagtgc tccgctgccg tgccgccgga
    16621 ggcgggctgt ggtgtgtcgt tcatacgctc catcctgccc cgaacggctg gggctttctc
    16681 agcggttgcc gactgccgcc gtgggggtgg tcaggccggg caggtggcga gcatgtcggc
    16741 cagcttggcc ttctccgcgt cggtgaccgt gagctggtag gcggctttga cggtggtcca
    16801 ggattccgcg taggcgcacc agtagtcctt ggcgggcggt gcccactggt ccgggctctg
    16861 gtcgcccttg gcccggttcg acgtcgccga gacggctacc agctgggggt gggtgaggtc
    16921 gttggcgaac gccttgcgct gctccgtcgt ccatgtactg gcccccgagc gccaggcgtt
    16981 ggccagcggc accgtgtggt cgatgtccat cttcgccgcg ctcgtgaacg ccaggtggtc
    17041 gtagcgggag atccaactgc ccgagacggc cttgcactcg gcgtccttcg tcacgccggt
    17101 tccgtcccgc tccaggacga tttcgcgggt gtcgcacttg gcgccctggg aggcccagtg
    17161 ggggaacttc tccctgctgt agcccgccat cgatcccacc gccgcgacct tcagtcccgc
    17221 cagctgcgca cgggccaccg acaccgtcgg cattcccggc agctgcttca cgtcgcccgg
    17281 cgcgccctgc gcaccacccg cacctggccg ggacgcggag accgacggcg acggcttgcc
    17341 gtcggcagcg ggtttgccgt cggtcgtatc ggagcatccg gctgctccga gaatgatcac
    17401 gactgccaaa caccctgcgg ccacgcggta ctgacggccc accatccacc ccttacatcg
    17461 aactgatgcc ctgaaactgg acaatctgcc ctgaccctac ccagcccggc gtcccgccca
    17521 tgcgcgcggc acaccccctg tccccgaacg cgcccgcttc agcccgcctg atccggcgcg
    17581 cagggaggcg ggtcggtgac ggcgggccgg tctcgatgtg gtcgaggccg gttggcggaa
    17641 cacgtcggcc cgggagggat gtactcagtc gtctgcacgt cgctgtaaga ccgcgcggaa
    17701 gtcctcctcc tcaatcagcc cggcgatcac gtcggccatg ctgtcgatgc cgggatcccg
    17761 gacgatcagg ccgtcggagg cccagaagta acgcccctcg agggcctcgc cgctccccgc
    17821 ccaggtcttc atcgggcgtt cgacctccgc gagggtgaac acggtcgcac tccatcgcga
    17881 gccgtccttg agtttcacta ggacttcgac gttgcacacg gagtccagct cttcgtcggg
    17941 gctcggcaga aacgatgcct cgaaggcgtc ggtgctgacc cggtaccagg acccgtccca
    18001 accccgttgg actgactcct gcagtggatt gcggctcatc atgcgagtgt tgccgtccgg
    18061 ctcgatgatc tccatcggat tccccagccg cacgcaccat tcccgcgccg gtgaggtgct
    18121 tctcggtcgc tcgtcggcac cccggtggcc cggtcggctc tgcctaccgc agcgccttgc
    18181 gcaatgcggc tgatgtgtgg gggtcggcgg cgtcggcctg gacggtgatg cggtcggtcc
    18241 cggtggtggt ggccagggtg tggcaggcgc tggcgaagcg cgcggcagcc tcggggcctg
    18301 cgtgcggttc gaatgaggct tggtggatgg tgaggccggc agaggtggag gcgaggtcgg
    18361 cgcgggcgac gagctggccg tcggccagga gggggcagac gtagtagccg tgttcgcggc
    18421 gggctgcggg tttgtatgcc tcgaatacct gggtgaagcc gaagagtctc tggacgcggg
    18481 ggcggtgcca gatgaggttg tcgaacgggc cgaggaacac tggctcccgc cgggcggctt
    18541 cggggcgcgc aagcgcggag ggatgagccc aggcggagct ccagccttgg acggcgactg
    18601 gagtgagcgc ggtgtccggc aggaggcgcg cggcgcttgc cgggcggatg cggaggtagt
    18661 cggcgaagtc gtcgacagtg cccacgccga gggtctttgc ggcgtgttcg aggagccgtg
    18721 tgaggcaggt gtcgtcgtcc agatcgtcgc cgaggagcgg gtgggggatg cagcgttcgg
    18781 gaaggtcgaa gaggcgttgg cctgcggtgt agcgggtgca ggcgaggtcg ccggcccaga
    18841 ccatgaactc gagggcggtc ttggtgggcc cccagcccca tccggtggtg gtgggctgct
    18901 cggtgcgcag gctgcgcaag ggcaggggcc cgtcggcgcg gatgcgggcg aggagggctg
    18961 cgcgctgtcc ggggtcgggg tactgggggc gggtgcgggt gtggcggcgt ctgaacgccc
    19021 acaggggcca gtcggtgagg ggcaccaggc tcagggcgtg ggcgggatag acgaacgccg
    19081 tgggcgggct ggcggagttg agggcggcgt cgacatcgcg ggtggtggtg tgggggatgc
    19141 gggtggcgag ggtgagctgg tgggcgcggg ccaggacgct gatgctgtcg agctgcacgg
    19201 catgcaggtg ccccagcgtc gacgggacgt caaggcggtc gccgggcggg aaggccgcgg
    19261 cgaccgcgat gctccgggcg tgtgccaggg acagttcgag accgggcctc ggtgtagcgc
    19321 tcacgcctgc cgccccgtca tgggttctgc tcgctcacag cctgggccgc cggtgacggt
    19381 gccggccgga cgacaacagc cctgggaggc agtccggttg cggtgtccgc cggctgccgc
    19441 tcccccgcgc cgggcacgac tggccgggag cggtgccggc tcatctggat gagggtggcg
    19501 gcggccccgg tggcggcgca gcaggtgagg gtgaacaggg cggtgttcca tttctgtgct
    19561 tggacgaggg ttccgatgat ggtggccatg atgccgttgg cgacgtcggc ggtggcgccg
    19621 atccaggtgt tggcctcgat acgtgtttcg tcggtggcgg tggcgtcggt cagcagaaag
    19681 gcgttgatga acagcggggt gacgaacagg cccgcgatca ggaggagggc ggcgaggagc
    19741 cagaggggcc gggcgaggaa gagcaggagg gcgggggtgg tgaagccgag ggtgaggatc
    19801 cggtatttgc gccacaggtc gctgcgccag ggtagggctg cgtaggcgat gccgccgagg
    19861 acgccgccgg tgctggtcgc ggcgaggagg gggccgagcc aggcggtggc gtgttggtgc
    19921 tgggtgtagg cggggaccag gatgccggtg ccgccgaaca gggcgcccat gaccaggagc
    19981 ggcagcagga tggccggcat gccgggcagg gcgagtggcc cgagccagcg tcgccttcga
    20041 ggccgcacgg tggtggccgg tgccggtgtg tgggtggggg tgaggtggtg gcggcgggct
    20101 gcggcgaggt agagggccat gaccgcgacg aagcaggcgg ccgctgtctc gtagccgtgg
    20161 cgggggccga gcaggacgag gacagtcccg gcggcgaggg gggccaggac gaagccggct
    20221 tcctccagca cgctgtcggc gctgtggacg gctttcagct gggcgtcccc ggtggccagg
    20281 cgccgccagg agctgcgcag ggcggcgttg agcggggggc tggtgagggt tgcggcgatg
    20341 accagcggga gggtggtggg ccagggccac gtgaagtgga tgctggcggc gaccagggcg
    20401 agcagcacgg tcgtggcaca cgccatggcc agcagcatgc gcggtccgca gcggtccagg
    20461 agacggccgc gcagcggcgc gcagagggcg aggaccaggg tgtaggtgcc gccgacggtc
    20521 gcggcccggg cgtagccgtg ggcatcggcg agcgccagga gcagcaggat gggcagggtc
    20581 gccgcggtgg tgcgggtcag gaaagcgatc gtgaggagtc cgcgcaccgg gcggccggtc
    20641 aacaggctta gcgtgctcgg gcgttcctcg tggtcaccag ggtctgcccc ggcgggtgtg
    20701 ctgaaggcgg tcaccgcgtc tcctccgctg cgtgggctgc ctcgggggga acgtgtacct
    20761 cggcggcagc ccggggcggg gtggtcgctg acgcggtggg agtgctgtgg gcggtggcgc
    20821 gcagcgagtc ggggtgcagg agcacgatcc gggcgatctc ctgtcctcgg tggatggaga
    20881 cggggtggtc gatttggacg gcgatgctca tgcctcctcg gtcggccatc gcgttgacgg
    20941 ccttggcggg gatcacgccg agcggcacgc ccagccccgg ggcgcagggg atgggtgggg
    21001 gcatgaccat gaggaaggtg ccgggcggga tctgggcggc gaagcccagg cgccattcca
    21061 cggtgccctg cccgttgggg atgaacatgc cttcccaacc gccggtgggc gtgcggtagt
    21121 cgccgaggtg gagccaggag gcatccccgg tggcgatcca gtccttgccg cgctggaaca
    21181 tgcgctggcc cccgaggcgg cggccgacct gctgggggtc ttccgcgtcg gggacggcca
    21241 ggccgatgtc ctcgaggggc cgcatcgtga gggtgagcgg ggagcgcagc gaccagccca
    21301 gttcctgtcc caggacccag ggcgggcagt cggcgggcag tcgggggatg cgcaggtagc
    21361 ggaacgagtc ctggtaggcg tcgcgttccg cgcgggcacc ggcccggtcg gccttcggct
    21421 tctcgggcag cagcgcccac gggtggagcg ggtgaaaggt gacctcggcc acttgcggtc
    21481 tgctctcagg cgggaaagca caggggattc agggggcctg gggtgcggtc gcgggcccga
    21541 cggctggccg ggcccgcgac ggccaagggg gccagggaag aacgggcgcg ggccgcgcct
    21601 tccctggtcc cggctggggt caggcgctgg tgtcggcgcg gttgaggcgg cgcaggcgct
    21661 cgggctcgga gagggtgtcg aggtcgaaca tgacgacgga gcagggcccg tagccgacgg
    21721 tgatctcctc gtaggtgaag gtgccttcgt cgcggtccag cggcgcggag gtgaggtcga
    21781 ccatggtgag gctgttgggg gcgaagttgg ggtgggcggc catcatgccg gcgcgggcga
    21841 agttggtgac gtagacggtc tggtcaccgg ggtcgacgac caggccgcgc ggtccggatc
    21901 cggtggggat ctggcgggtc acggcgaggg tctcgacgtc gatgacggcg atggtggagg
    21961 agttttcgac cgtgacgagc gcgtggcggc catcgggggt gaaggcgacg ccgcggccgc
    22021 cggtggaggc gacgtccacg cggtgggtct ggtcggtggc ggtgtcgatg acggtggtgt
    22081 agtcggcctg cgtgttggcg acgaacaccc gccggcccga ggggtcgatg cccaggctgt
    22141 aggggtgggc ttcgcggtcg acggggatct gcgcgagttc gctgacgccc agcgggttgc
    22201 cgtcggccag cgccgagatg tcgagcttgc tgacgtaacc gccgccccag atgcagacgt
    22261 aggcgagggt gccgtccttg ctgatgccca tgtggcgggg gtcgcggccg gtggcgatct
    22321 ggtggacctc gacattgagt tcgaggtcga cgaccgagat cgtgttggag ccggagttgg
    22381 agaccagcag gtacttgtcg cccgggacca ggccctgtcc gcgcgggccg tgaccgacct
    22441 cgatccggcg gacctcgttc agggcgaccg cgtcgatctc cgagatggtg ttctg
//
