LOCUS       NZ_BMUU01000013        31478 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence13, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000013
VERSION     NZ_BMUU01000013.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 254178)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 222700
            Orig. end                         :: 254178
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31478
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /contig_edge="True"
                     /product="butyrolactone"
                     /product="PKS-like"
                     /product="amglyccycl"
                     /region_number="1"
                     /rules="AfsA"
                     /rules="(t2pks2 or ksIII)"
                     /rules="(DOIS or ValA or salQ or strH or strK1 or strK2 or
                     NeoL or SpcFG or SpcDK_glyc)"
                     /tool="antismash"
     cand_cluster    1..31478
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="AfsA"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="neighbouring"
                     /product="butyrolactone"
                     /product="PKS-like"
                     /product="amglyccycl"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /tool="antismash"
     cand_cluster    1..10942
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10942
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5942](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5942
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     gene            complement(308..1018)
                     /db_xref="GeneID:96294151"
                     /locus_tag="IE233_RS30700"
                     /old_locus_tag="GCM10010326_62530"
     CDS             complement(308..1018)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050268.1"
                     /locus_tag="IE233_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62530"
                     /product="MgtC/SapB family protein"
                     /protein_id="WP_190028869.1"
                     /transl_table=11
                     /translation="MAAGVLEPSGQGWVQAGEFGLAFLLSAAIGLEREIRQKAAGLRTY
                     TTVGVGSALFTLVSKYGFGDVLSAGTIELDPSRVTAQIVSGVGFIGAGVIFVHRGSVQG
                     LTTAATIWLTAAVGAAAAAGLPLLSILATAAYFLAAYLVRPLVHRLPQMRSVPSTFRIA
                     YEQRPGLLRELMEQCERAGFSVAGLQMLRAGGTGDPAEVLISAVGRADPAVLTARFADV
                     ANVVAVTRGGNEDE"
     gene            complement(1146..2669)
                     /db_xref="GeneID:96294152"
                     /locus_tag="IE233_RS30705"
                     /old_locus_tag="GCM10010326_62540"
     CDS             complement(1146..2669)
                     /codon_start=1
                     /db_xref="GeneID:96294152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540933.1"
                     /locus_tag="IE233_RS30705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62540"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190028846.1"
                     /transl_table=11
                     /translation="MHVEDLLRLESLDLELLWGEEQQLLREITGVTATDLEDPTRFLRP
                     GEVVLSGLVWWAPEKGSEKISRFVSALVTAGAAALLAGEETHGSVPEELTRSCRENGIA
                     LLAVPSRTNFRAITEAVYLRQWGDLSRRPTSHRHALPDNVRSELSDLVRAGAEPDVLLD
                     RALAHVGTPDCYVLTPTGRTVARTPGAPEIPAQRGRDLLRRAPDGLTLLIDTDSSPYDS
                     WHLHLADAAAVPPRLLHETADVLAGHRYGRDRARNEIRRRAGELIRLVDAPATDLPALN
                     GALTACGLSPDGPFHVIGAAARADGDQAAAADALAEALRHTPDRPFALGRLPHGEVLAV
                     VQGGSEVALKLRDLWRVVQACEPLVPLHVGVGAQVDTPDRLNSSLTGARYALAAARTRE
                     PEGAGVAAVDELGTLEGLLAGIPDDVRTIYHHKVLGPLADDAHTSSQMLRETLESFLAH
                     NGSWARTAASLHLHVNTVHYRIQRIEVLTGRDLSRLEHKLDMYAALRCR"
     misc_feature    complement(2690..2706)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.53"
                     /tool="antismash"
     gene            complement(3153..3917)
                     /db_xref="GeneID:96294153"
                     /locus_tag="IE233_RS30710"
                     /old_locus_tag="GCM10010326_62550"
     CDS             complement(3153..3917)
                     /NRPS_PKS="Domain: PKS_KR (7-185). E-value: 7.1e-08. Score:
                     24.5. Matches aSDomain:
                     nrpspksdomains_IE233_RS30710_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:96294153"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006608009.1"
                     /locus_tag="IE233_RS30710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62550"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_161255281.1"
                     /sec_met_domain="adh_short (E-value: 4e-31, bitscore:
                     102.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGALKGRTALVTGASRGIGRGVAQRLAADGATVAVHYGGNEDAAL
                     GVVDEIREAGGAAFAVGADLRRPDAARVLYREFDAALVELGVGPGLDILVNNAAIGPLG
                     DIEAATEEHFDEMFTVNARGPFFLTKYGLERMREGGRIVNVSSAVTRTAFPESIAYSMS
                     KGAVDVFTLALAKHVGSRGITVNTVAPGFVETDMNAALRQSPEAAAGLAAYSVFNRMGR
                     PADIADAVAFLVSEEARWITGQWISVSGGSGL"
     cand_cluster    3289..31478
                     /SMILES=""
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="(t2pks2 or ksIII)"
                     /kind="single"
                     /product="PKS-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    3289..31478
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[23288:24332](-)"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(23289..24332)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="2"
     aSDomain        complement(3363..3896)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS30710_PKS_KR.1"
                     /evalue="7.10E-08"
                     /label="IE233_RS30710_PKS_KR.1"
                     /locus_tag="IE233_RS30710"
                     /protein_end="185"
                     /protein_start="7"
                     /score="24.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGASRGIGRGVAQRLAADGATVAVHYGGNEDAALGVVDEIR
                     EAGGAAFAVGADLRRPDAARVLYREFDAALVELGVGPGLDILVNNAAIGPLGDIEAATE
                     EHFDEMFTVNARGPFFLTKYGLERMREGGRIVNVSSAVTRTAFPESIAYSMSKGAVDVF
                     TLALAKHVGSRGITV"
     CDS_motif       complement(3825..3890)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS30710_0001"
                     /evalue="2.70E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE233_RS30710"
                     /protein_end="31"
                     /protein_start="9"
                     /score="13.6"
                     /tool="antismash"
                     /translation="LVTGASRGIGRGVAQRLAADGA"
     gene            complement(4033..4689)
                     /db_xref="GeneID:96294154"
                     /locus_tag="IE233_RS30715"
                     /old_locus_tag="GCM10010326_62560"
     CDS             complement(4033..4689)
                     /codon_start=1
                     /db_xref="GeneID:96294154"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676872.1"
                     /locus_tag="IE233_RS30715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62560"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_161255284.1"
                     /transl_table=11
                     /translation="MARQERAIRTRNAVLEAAATVFAEHGYESATIMQILDRAQVTKGA
                     LYFHFTSKEDLARGVLEHAVTEPPPEQPVKVQSFIDMGLLLAHRLPREPLLRGAARIAA
                     DQSAQRFFGQPWQDWVKLTAQQLTAAKEQGEVLPYVDPERTAQTMVAAFTGTQLMSQAS
                     TQMSDLEERVSLLYDLVLPSIAVPGVLGRLDTSPERGARLYAEYRVAVEARSAGG"
     misc_feature    complement(4933..4951)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.99"
                     /tool="antismash"
     gene            5001..5942
                     /db_xref="GeneID:96294155"
                     /locus_tag="IE233_RS30720"
                     /old_locus_tag="GCM10010326_62570"
     CDS             5001..5942
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294155"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041195.1"
                     /locus_tag="IE233_RS30720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62570"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_161255287.1"
                     /sec_met_domain="AfsA (E-value: 3.7e-18, bitscore: 59.3,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEIDRDTHIQTTSTLLGHIPALGRPDPAISAAFAHRAAAEDVLV
                     AGWRRRSDTVFSIAVDWSKQHNFFAPARGSAHHHMLIAQTLRQIGLGLTHAGLDVAAGT
                     NHFLLDDLRYSADPRHRTDTLAPVRAEAEYTWTGRRSLRVQISLQQGGTLFVTSSSHFT
                     WVPDGVYRRLRGDYLTARPRAWATPVEPSVVGRHSPDEVTLADTGVPHRWELISDTGHP
                     ALIDHAVDHVPGLVLLEAAQQAAYAFAGSDGFNPLSTAIQAQRYVEFDAPCFVEARAIP
                     AWSPGALAVEVTGIQRGEATFRCQIQGTPAHE"
     gene            complement(6006..7319)
                     /db_xref="GeneID:96294156"
                     /locus_tag="IE233_RS30725"
                     /old_locus_tag="GCM10010326_62580"
     CDS             complement(6006..7319)
                     /codon_start=1
                     /db_xref="GeneID:96294156"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979512.1"
                     /locus_tag="IE233_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62580"
                     /product="cytochrome P450"
                     /protein_id="WP_229892962.1"
                     /sec_met_domain="p450 (E-value: 1.6e-19, bitscore: 63.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRERRMPNMQECPFRMDAAGRDIQGEAERVRRAGPAVRIELPGGV
                     PAWAVADPEAMRRLLASPDVSKDAVRHWPAWTNGEVPQDWALAMWVSIRSMFTAYGPEH
                     TRLRKLVSSAFTAHRTKALEPVVRRIAAELLDEIAELPAGRPLDLRARFAVPLPARLIC
                     DLFGVPRERRDELCAIFDCLFDTSADAAAVGRAAAELYGILHELVAAKREFPGDDLTSG
                     LVLRQRETLEQSDEAPLDDQELLDTLVHLLSAGYETTVNLIDHAVHALLTHPEQLQLVL
                     AGRASWEDVVEETLRWEPAAANLMLRYAVQDIDLGDVVIPRGEAIVLSVAGAGRDPGTH
                     GDDADRFDITRPSRRAHLAFGHGVHHCLGAPLARMEGVIALSALFERFPGLSLAVPSGA
                     LRPVASFISNGHQELPVLVGAPAPAVPSAGRAPAGAAG"
     misc_feature    complement(7339..7354)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.97"
                     /tool="antismash"
     misc_feature    7478..7490
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.33"
                     /tool="antismash"
     gene            complement(7537..8163)
                     /db_xref="GeneID:96294157"
                     /locus_tag="IE233_RS30730"
                     /old_locus_tag="GCM10010326_62590"
     CDS             complement(7537..8163)
                     /codon_start=1
                     /db_xref="GeneID:96294157"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985133.1"
                     /locus_tag="IE233_RS30730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62590"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_161247190.1"
                     /transl_table=11
                     /translation="MTKQERAVTTRRDLIRSAAVAFDRYGYAQATLSDISKQAGVSTGA
                     LHFHFANKAALAEAVEEDATEALRSVVREAYRSRESALQALTDASHGVLRLLRGNIVFR
                     AGFQLNADFTWESGLDLRREWHTCVRRFVDEAAQEGALVDDVVPGDVTVTIMAVMTGYG
                     LLGREEREWFSQRMLTGFWELLLPRIAAADTVDALVPGGGPVPPA"
     misc_feature    complement(8248..8261)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.37"
                     /tool="antismash"
     misc_feature    complement(8438..8454)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.53"
                     /tool="antismash"
     gene            8530..9771
                     /db_xref="GeneID:96294158"
                     /locus_tag="IE233_RS30735"
                     /old_locus_tag="GCM10010326_62600"
     CDS             8530..9771
                     /EC_number="2.8.2.-"
                     /codon_start=1
                     /db_xref="GeneID:96294158"
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_3: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024860.5"
                     /locus_tag="IE233_RS30735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62600"
                     /product="sulfotransferase"
                     /protein_id="WP_190028848.1"
                     /transl_table=11
                     /translation="MQRVSDIHVTVPDQRSKGCAQGRSGRPGGQRPVGPVLIDLDELRF
                     RAQAQHPGDDVPSPRFLPELGRLAEAVNSEAGLTPQGAAAVRERLVSALEQQTRLAALA
                     QEAPETAATHIRNPVFISGLPGSGASMLQNLLVEHPSVDSPTLWEMLYPVSPGAGSPGR
                     RMLIGQARAHVEASRHPVRHRTVGRFREATRPGGCHQLLANAFQSPVSGMYLRIPEYVR
                     ELEAADLTAAYAFHREQLQAITSRIPVASLVLRAPFHAARVDDLLRVYPDARIIRVHRD
                     PAALVTITAGLSAGLRRTTSSRVAPKEVGREWADHIERHLARTSQAGRRLGPDRLLDVR
                     HADLVAAPAATVRRVLQFIGVEPTPAVLDNVECLARATAAPTPNAHRFQADDFGLSTDE
                     LRERFASHIETYAL"
     gene            9947..10405
                     /db_xref="GeneID:96294159"
                     /locus_tag="IE233_RS30740"
                     /old_locus_tag="GCM10010326_62610"
     CDS             9947..10405
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294159"
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894812.1"
                     /locus_tag="IE233_RS30740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62610"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_161247194.1"
                     /transl_table=11
                     /translation="MTAGRGRRDGEVELWRQLTVLTSRISNTLDKRLQRGHGVSVAEYT
                     ALVVMRDNAKSGGVRMQDLAEAVGLSQSTVSRLVARLENEGLAGRVISEEDRRVMYAQI
                     SEQGTAVIADAAATFQKELTTALDVASFDEQTASLVARLRHNPATAGG"
     gene            complement(10508..11443)
                     /db_xref="GeneID:96294160"
                     /locus_tag="IE233_RS30745"
                     /old_locus_tag="GCM10010326_62620"
     CDS             complement(10508..11443)
                     /codon_start=1
                     /db_xref="GeneID:96294160"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017945480.1"
                     /locus_tag="IE233_RS30745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62620"
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="WP_190028849.1"
                     /transl_table=11
                     /translation="MDERGTTAVVELVSGPKEGAGLDAGAERIDRVGVVGCGTMGAGIV
                     ELCARAGRDVRVAVSSADSHVRGAARIRASLDRGVAKGRITEADRAAALDRISFTTDLG
                     ELADRQLVIESVREDEQAKAEVFATLDKVLVSKDAIIATNTSSLSVARLARATRRPGKV
                     IGIHFFNPVPVLPLVELVGSVLTEPGTRTRAADFVAGVLGKTVISAPDRAGFLVNALLF
                     PYLLSAVRMVDSGLATPEVVDQGMELGCAHPMGPLRLADLIGLDTTVSIAQAMYEETKE
                     TLYAPPPLLLRMVECGLLGKKSGRGFYTYA"
     gene            complement(11449..12798)
                     /db_xref="GeneID:96294161"
                     /gene="ccrA"
                     /locus_tag="IE233_RS30750"
                     /old_locus_tag="GCM10010326_62630"
     CDS             complement(11449..12798)
                     /EC_number="1.3.1.85"
                     /GO_function="GO:0043880 - crotonyl-CoA reductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (49-410). E-value: 3.4e-22.
                     Score: 70.9. Matches aSDomain:
                     nrpspksdomains_IE233_RS30750_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:96294161"
                     /gene="ccrA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483820.1"
                     /locus_tag="IE233_RS30750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62630"
                     /product="crotonyl-CoA carboxylase/reductase"
                     /protein_id="WP_189766144.1"
                     /sec_met_domain="ADH_N (E-value: 1.7e-10, bitscore: 34.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-25, bitscore:
                     84.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSLADAVLNGATPAQLEREPLPGDYPAVHTRAEDVEMFRGVDDK
                     DVRKSLHVGRVPMPELAPDEVLVAVMASSINYNTVWSATFEPVSTFAFLNKLGKQGGWA
                     ARHDQPHHVLGSDASGVVVRAGSAVRRWKAGDHVVVSCVQVDDQEPATHADGMMGAEQR
                     IWGYETNFGGLAHYTVVRASQLLSKPAHLTWEESASTMLTAATSYRMLISDRGARIKQG
                     DIVLIWGATGGLGAFAVQLVKNAGGIPVGVVSSQAKAEILRRMGCDVVIDRTEIGMDGD
                     AAPSPEKTIELGKRLGRAIRERVGEDPHVVFDFIGQATFGISVFVVRRGGAVVTCGSST
                     GYTHQFDNRYLWMNLKRIIGSHAANLQEQWECNRLFKLGMLSPVLSATYPLAEAAEAAR
                     LVQTNRHTGKVGVLALAPEPGLGITDPELRARIGEERLSPLAPRVPALAG"
     aSDomain        complement(11569..12651)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS30750_PKS_ER.1"
                     /evalue="3.40E-22"
                     /label="IE233_RS30750_PKS_ER.1"
                     /locus_tag="IE233_RS30750"
                     /protein_end="410"
                     /protein_start="49"
                     /score="70.9"
                     /tool="antismash"
                     /translation="SLHVGRVPMPELAPDEVLVAVMASSINYNTVWSATFEPVSTFAFL
                     NKLGKQGGWAARHDQPHHVLGSDASGVVVRAGSAVRRWKAGDHVVVSCVQVDDQEPATH
                     ADGMMGAEQRIWGYETNFGGLAHYTVVRASQLLSKPAHLTWEESASTMLTAATSYRMLI
                     SDRGARIKQGDIVLIWGATGGLGAFAVQLVKNAGGIPVGVVSSQAKAEILRRMGCDVVI
                     DRTEIGMDGDAAPSPEKTIELGKRLGRAIRERVGEDPHVVFDFIGQATFGISVFVVRRG
                     GAVVTCGSSTGYTHQFDNRYLWMNLKRIIGSHAANLQEQWECNRLFKLGMLSPVLSATY
                     PLAEAAEAARLVQTNRHTGKV"
     CDS_motif       complement(12076..12135)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS30750_0002"
                     /evalue="5.90E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE233_RS30750"
                     /protein_end="241"
                     /protein_start="221"
                     /score="12.6"
                     /tool="antismash"
                     /translation="GDIVLIWGATGGLGAFAVQL"
     CDS_motif       complement(12421..12459)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS30750_0001"
                     /evalue="5.00E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="IE233_RS30750"
                     /protein_end="126"
                     /protein_start="113"
                     /score="9.9"
                     /tool="antismash"
                     /translation="LGSDASGVVVRAG"
     misc_feature    complement(12789..12804)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.53"
                     /tool="antismash"
     gene            complement(12933..13745)
                     /db_xref="GeneID:96294162"
                     /locus_tag="IE233_RS30755"
                     /old_locus_tag="GCM10010326_62640"
     CDS             complement(12933..13745)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (32-202). E-value: 1.3e-11.
                     Score: 36.6. Matches aSDomain:
                     nrpspksdomains_IE233_RS30755_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:96294162"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.5"
                     /locus_tag="IE233_RS30755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62640"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_161247201.1"
                     /sec_met_domain="adh_short (E-value: 2.5e-32, bitscore:
                     106.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.2e-35, bitscore:
                     116.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCIKFSRKQHRKKTTKGMTLMTTQTAKRLQGKTALVTASSRGIGR
                     AVALRLAADGADVAVTYQSNAAAAQEVVDAVVAAGGKAIALQADFAKKDEIENLYKEVL
                     NAFGSLDIVVNNAGIAGNGNIADVDDETFERAVDVNFKGTFYSLRQAATHVSDGGRIIN
                     ISTGYTHSTFAGTGVYTATKAAVEQLGLALAREVGGRGVTVNSVLPGLIRTDQTAPIAD
                     QYDTFAQMMPLGRIGEPEDIAGVVAFLASDDASYITGQYLAAAGGLVS"
     aSDomain        complement(13140..13649)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS30755_PKS_KR.1"
                     /evalue="1.30E-11"
                     /label="IE233_RS30755_PKS_KR.1"
                     /locus_tag="IE233_RS30755"
                     /protein_end="202"
                     /protein_start="32"
                     /score="36.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTASSRGIGRAVALRLAADGADVAVTYQSNAAAAQEVVDAVV
                     AAGGKAIALQADFAKKDEIENLYKEVLNAFGSLDIVVNNAGIAGNGNIADVDDETFERA
                     VDVNFKGTFYSLRQAATHVSDGGRIINISTGYTHSTFAGTGVYTATKAAVEQLGLALAR
                     EVGGRGV"
     CDS_motif       complement(13578..13643)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS30755_0001"
                     /evalue="1.20E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE233_RS30755"
                     /protein_end="56"
                     /protein_start="34"
                     /score="8.3"
                     /tool="antismash"
                     /translation="LVTASSRGIGRAVALRLAADGA"
     misc_feature    complement(13732..13746)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.39"
                     /tool="antismash"
     gene            complement(13831..15468)
                     /db_xref="GeneID:96294163"
                     /locus_tag="IE233_RS30760"
                     /old_locus_tag="GCM10010326_62650"
     CDS             complement(13831..15468)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294163"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030784.1"
                     /locus_tag="IE233_RS30760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62650"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_229892963.1"
                     /transl_table=11
                     /translation="MTSTVTRRRFVKRTATGVGVAAVGTGLGAGIFAPPAATAAGESTG
                     STAFGPVTVASTDSRYADLRRGTNQRFEGNPESIRLVGSTSQVVAAVQSAVSAGKKIAV
                     RSGGHCYEDFVANAAVKVVIDLSAMNAVGFDSGRNAFVIEAGAKLGQVYERLFKGWGVT
                     VPGGACPTVGAGGHIQGGGYGALSRRYGLISDHLYAVEVVVVDRTGTAKAVVATREASD
                     PNRDLWWAHTGGGGGNFGVVTRYWMRAPGATGSDPSKLLPKAPSEVWISTVNWPWAGLT
                     KDGFGRLMKNYAQWHIDNSAPGSAQLSLFSELKPSHRAAGAISLTVQVEASAPGAEQML
                     DDFVAYVGAGTGVTAQVADHRKVPWLHATQWSGFTGPDPLFRFKGKPAYQRKNFTAAQL
                     DAMYKHLTRTDYEYPAALMLISAYAGKVNEVGPADTAVAQRDSILKVQTAVLWTDAADD
                     AKHLAWVREFFRDLYSETGGVPGLNGVTDGMFINYADADVKDPAWNASGTPWQQLYYKG
                     NYAALQQAKAKWDPRNTFSHALSVELPS"
     gene            complement(15465..16733)
                     /db_xref="GeneID:96294164"
                     /locus_tag="IE233_RS30765"
                     /old_locus_tag="GCM10010326_62660"
     CDS             complement(15465..16733)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294164"
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894815.1"
                     /locus_tag="IE233_RS30765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62660"
                     /product="MFS transporter"
                     /protein_id="WP_190028850.1"
                     /transl_table=11
                     /translation="MPAPLFALVLSVFSLGTAESVIAGLLPQLSTDLDVSLSQAGLLVS
                     GYAVAIVVGGPLVTLMTSRLPRKPLLIGLLALFVAGNVLAALAPGYGVLMTARVLSALS
                     HCTLFALALIAAAEIAGPRKSGSAVARIIIGVNLATIVGVPLGLLLAQQWGWRATFWGV
                     TVLSLTALLACVLLVPATSAGAGGGVAAELSVLRDRRVRVALLLTVVGMGGGFTAFTFL
                     TPLLERVSGFSGHQVTLLLFLFGLGSLAGGALGGKLADRALMGSLTALLAVLTVVLVAF
                     AGVAPQPVAAVGALVVFSIVFFALNPGLGARILNSVSGRAPTLAVAMSIASVQTAIALG
                     SWLGGRVLDLGHGLRSVFLAAAVLTLAGCSIAWCEWRADRRASRTPESTPLTGAATAPA
                     APHLRTAPGGVRRRPPENVRTQK"
     cand_cluster    15823..31478
                     /candidate_cluster_number="4"
                     /contig_edge="True"
                     /detection_rules="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="single"
                     /product="amglyccycl"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    15823..31478
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[25822:27067](+)"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      25823..27067
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="3"
     gene            complement(16775..18004)
                     /db_xref="GeneID:96294165"
                     /locus_tag="IE233_RS30770"
                     /old_locus_tag="GCM10010326_62670"
     CDS             complement(16775..18004)
                     /codon_start=1
                     /db_xref="GeneID:96294165"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155834.1"
                     /locus_tag="IE233_RS30770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62670"
                     /product="cytochrome P450"
                     /protein_id="WP_161247205.1"
                     /sec_met_domain="p450 (E-value: 5.3e-28, bitscore: 91.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTISATAGTPEAISFGGEANPYALYARLRRQAPVSHMSLPDGGEF
                     WLVTRYEDAKNALADPRLSKDPNRVGERWRATVAQPTDGEDASLVRHLLNVDPPDHTRL
                     RRLVHKGFTPRRIEALRGRIQEITDGLLAELDATEGSVDLLDKFAFKLPVTVICELLGV
                     PLADVDDIHDWSTALSTLVADEEGHARVGKAAGQLGAYLDELVAHKAEHPGDDLISALI
                     EARDEGQRLSHGELTAMAFLMLIGGHETTVHLIGNGMLALMQHPDQLALLHNDPSLITS
                     AIEEFLRYEGSVEVATWRFALEDLDFDDVRVPAGAPVLVSLGSAGRDPDRFENPDTFDI
                     TRGDAGHLVFGHGMHYCLGAPLARMEGQIAVGSLVRRFPAIRLAAPVDTLRWREGLLIR
                     GLYELPVHLR"
     misc_feature    complement(17993..18008)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.53"
                     /tool="antismash"
     misc_feature    complement(18102..18118)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.98"
                     /tool="antismash"
     gene            complement(18214..19395)
                     /db_xref="GeneID:96294166"
                     /locus_tag="IE233_RS30775"
                     /old_locus_tag="GCM10010326_62680"
     CDS             complement(18214..19395)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294166"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013884.5"
                     /locus_tag="IE233_RS30775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62680"
                     /product="acyltransferase"
                     /protein_id="WP_190028851.1"
                     /transl_table=11
                     /translation="MPRTTDSPVAPGSSRLPTLTGMRFIAAALVFLHHGIWVNVFSDKD
                     VVSFYHDLFITAGHVGVSFFFLLSGFVLTWSARRKDTYKRYLRRRIAKLYPNHVVTFVA
                     ALLLVATSTQLYQAISNLFMVQSWFPVYSLLFSVNPPSWSLACEALFYVAFPLLLRWAN
                     RIPVEKLWWWVAGVVAAVIGVAVIAQVVITDGPAMPDGQPLGLYQFWFVYALPPVRALD
                     FFLGILLARIVINGKWIRVGVLPAALLFVACYALAGQLPYVYGLNAATIIPIALLVPAA
                     AVADINGWRTGLRGRFAIWLGEISYAFYLVHAIVLIWCRGQLGNPQGWSTPAGIALLLG
                     GLVLSVLVAWALYALVERPAMRRWSRPRADRIASGPKVATPAEAGQSELAGTR"
     gene            19681..20589
                     /db_xref="GeneID:96294167"
                     /locus_tag="IE233_RS30780"
                     /old_locus_tag="GCM10010326_62690"
     CDS             19681..20589
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (17-192). E-value: 4.2e-30.
                     Score: 96.9. Matches aSDomain:
                     nrpspksdomains_IE233_RS30780_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:96294167"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894816.1"
                     /locus_tag="IE233_RS30780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62690"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_190028852.1"
                     /sec_met_domain="ADH_N (E-value: 1.1e-11, bitscore: 38.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALTLAEYGGPELLTVSELPSPAPRAGQILVRTAASGVNPVDLL
                     VRGGAMAANISHPFPLVLGWDLSGTVEAVGAGVDRFAPGDRVVAMSAQYATGIGTHAEF
                     VALPAAIAAPAPRTVDLVEAAALPLAGLTAYQALEKLAPRSGERLLISGAVGAVGGFAT
                     QLAASRGVEVIALARPQDAELARELGASSVLSADEPLPTAIADVLLETAGIAPKVIGAV
                     RDEGRAGSIYAPEPPKAERGITVLQTFVEQDGDQLAILSALVDEGVLTLRVAEIGDFAF
                     GPEAHRRLAAGGSRGKFLLTP"
     aSDomain        19732..20256
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS30780_PKS_ER.1"
                     /evalue="4.20E-30"
                     /label="IE233_RS30780_PKS_ER.1"
                     /locus_tag="IE233_RS30780"
                     /protein_end="192"
                     /protein_start="17"
                     /score="96.9"
                     /tool="antismash"
                     /translation="SELPSPAPRAGQILVRTAASGVNPVDLLVRGGAMAANISHPFPLV
                     LGWDLSGTVEAVGAGVDRFAPGDRVVAMSAQYATGIGTHAEFVALPAAIAAPAPRTVDL
                     VEAAALPLAGLTAYQALEKLAPRSGERLLISGAVGAVGGFATQLAASRGVEVIALARPQ
                     DAELARELGASS"
     CDS_motif       20050..20094
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS30780_0001"
                     /evalue="5.40E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="IE233_RS30780"
                     /protein_end="138"
                     /protein_start="123"
                     /score="10.4"
                     /tool="antismash"
                     /translation="AAALPLAGLTAYQAL"
     CDS_motif       20116..20178
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS30780_0002"
                     /evalue="3.50E-02"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE233_RS30780"
                     /protein_end="166"
                     /protein_start="145"
                     /score="7.0"
                     /tool="antismash"
                     /translation="GERLLISGAVGAVGGFATQLA"
     gene            complement(20690..21478)
                     /db_xref="GeneID:96294168"
                     /locus_tag="IE233_RS30785"
                     /old_locus_tag="GCM10010326_62700"
     CDS             complement(20690..21478)
                     /NRPS_PKS="Domain: ECH (12-250). E-value: 1.6e-66. Score:
                     216.1. Matches aSDomain:
                     nrpspksdomains_IE233_RS30785_ECH.1"
                     /codon_start=1
                     /db_xref="GeneID:96294168"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036299.1"
                     /locus_tag="IE233_RS30785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62700"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_373300265.1"
                     /transl_table=11
                     /translation="MNEVEPAVRLVVADGIGTIELSRAPVNALDHAAQAQLREAAQEAA
                     DRRDVSAVVLYGGPDKFSAGADIREMAGLEPIDMVLWAARLQGAFTAVADIPKPVVAAV
                     TGFALGGGCELALTADHRILAPEVKIGLPEVKLGVIPGAGGTQRLSRLVGTARAKEIMF
                     TGRALSAQEALEIGLADRVVARDRVLTEALAWASQFVGGPSLALRAIKQAVDLGTGTDL
                     RSGLELERTLFEGLFGTRDQLTGMRTFVADGPGKAVFTGR"
     aSDomain        complement(20729..21442)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS30785_ECH.1"
                     /evalue="1.60E-66"
                     /label="IE233_RS30785_ECH.1"
                     /locus_tag="IE233_RS30785"
                     /protein_end="250"
                     /protein_start="12"
                     /score="216.1"
                     /tool="antismash"
                     /translation="ADGIGTIELSRAPVNALDHAAQAQLREAAQEAADRRDVSAVVLYG
                     GPDKFSAGADIREMAGLEPIDMVLWAARLQGAFTAVADIPKPVVAAVTGFALGGGCELA
                     LTADHRILAPEVKIGLPEVKLGVIPGAGGTQRLSRLVGTARAKEIMFTGRALSAQEALE
                     IGLADRVVARDRVLTEALAWASQFVGGPSLALRAIKQAVDLGTGTDLRSGLELERTLFE
                     GLFGTRDQLTGMRTFV"
     gene            complement(21475..22215)
                     /db_xref="GeneID:96294169"
                     /locus_tag="IE233_RS30790"
                     /old_locus_tag="GCM10010326_62710"
     CDS             complement(21475..22215)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-164). E-value: 4.3e-16. Score:
                     51.3. Matches aSDomain:
                     nrpspksdomains_IE233_RS30790_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:96294169"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657285.1"
                     /locus_tag="IE233_RS30790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62710"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_161247211.1"
                     /sec_met_domain="adh_short (E-value: 6.6e-39, bitscore:
                     127.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.6e-36, bitscore:
                     119.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLKDKVTVVTGGTRGLGRAIAERFVDEGATVVCAARNPYDIQQL
                     INQLPDRVLFHETDVTDPDSVDGLMDAAVAAYGRIDVLVANAGVNRDGKVDRLTPEDWR
                     SMMDTNLNGAFYSLQSAARRMIPQGGGRIITVSSSMASRVAIGAAGYSATKAAIETLTK
                     VSAIELGRKGIQVNCLAPGVLEDGMGRELSQNKKVWEAYHHRFSLGRAGKLDEAALGAV
                     FLASEDSSYVNGHVLEVNGGLLWA"
     aSDomain        complement(21724..22197)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS30790_PKS_KR.1"
                     /evalue="4.30E-16"
                     /label="IE233_RS30790_PKS_KR.1"
                     /locus_tag="IE233_RS30790"
                     /protein_end="164"
                     /protein_start="6"
                     /score="51.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VTVVTGGTRGLGRAIAERFVDEGATVVCAARNPYDIQQLINQLPD
                     RVLFHETDVTDPDSVDGLMDAAVAAYGRIDVLVANAGVNRDGKVDRLTPEDWRSMMDTN
                     LNGAFYSLQSAARRMIPQGGGRIITVSSSMASRVAIGAAGYSATKAAIETLTKV"
     CDS_motif       complement(21799..21861)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS30790_0002"
                     /evalue="2.00E-01"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE233_RS30790"
                     /protein_end="139"
                     /protein_start="118"
                     /score="4.4"
                     /tool="antismash"
                     /translation="QSAARRMIPQGGGRIITVSSS"
     CDS_motif       complement(22123..22191)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS30790_0001"
                     /evalue="5.00E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE233_RS30790"
                     /protein_end="31"
                     /protein_start="8"
                     /score="25.6"
                     /tool="antismash"
                     /translation="VVTGGTRGLGRAIAERFVDEGAT"
     gene            complement(22231..23214)
                     /db_xref="GeneID:96294170"
                     /locus_tag="IE233_RS30795"
                     /old_locus_tag="GCM10010326_62720"
     CDS             complement(22231..23214)
                     /codon_start=1
                     /db_xref="GeneID:96294170"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359650.1"
                     /locus_tag="IE233_RS30795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62720"
                     /product="3-oxoacyl-ACP synthase III family protein"
                     /protein_id="WP_161247213.1"
                     /sec_met_domain="fabH (E-value: 8.8e-85, bitscore: 278.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVGIIGLGAYAPPRVIDNEQISTWTGVTPEWIAERTGVHGRHYA
                     DPGVTTSAMAARAVEELFADSPHSRERVGLTVLATSTPDQPQPATAVRMQKLLRMHSTP
                     AFDVNAVCSGFVYGLTVAESMLRTSPDNGTALVIGADMYSSIMDRGDRRTVSLFGDGAA
                     AVLLGEVPEGYGIHATRLYADGDGEDLVEVAAGGTRETADDAAREAGRHFFRMQGRSVK
                     EYALQIIPKTVDDVLSQARLEIGDIDRVFIHQGNTRLVEAVAAQLGVDMSRVPLTAPQF
                     GNTGAASIPFTLRHSHRERPIERGERILFAAVGGGMTAGAAVLTWY"
     misc_feature    complement(23188..23202)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            complement(23289..24332)
                     /db_xref="GeneID:96294171"
                     /locus_tag="IE233_RS30800"
                     /old_locus_tag="GCM10010326_62730"
     CDS             complement(23289..24332)
                     /codon_start=1
                     /db_xref="GeneID:96294171"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF020130.5"
                     /locus_tag="IE233_RS30800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62730"
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="WP_167152126.1"
                     /sec_met_domain="ksIII (E-value: 1.8e-85, bitscore: 280.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWDHLYVAGTGAYLPKTMSVEDAIDAGVYDEESARHSGHLSVTV
                     AAPEDSIPEMAVRAGQQALRRSGYRPEDVAAVTYSVVFHNGIDIWNSGSYIQKGIAAPG
                     CLAAEVRSGSNGGLVAAELAAGYLHAHPTAKVAVSTAGDLWTDPYFDRWRTDRILYGDG
                     AAAVALSREGGFARIVSMATYTDPELEAMHRGHEPFGPFQHDAEHPIDLNRRHQQFLED
                     FDKDEVWRRVEGGLQKAANQALEEAGRSMDEMDHLVAPHFGAGLTLRQCLRPLGVEDLN
                     RTAWDFSRRTGHLGPADQFAGLNHLTETGALTPGKRVLLLGVGGGFSWTCAVLDILEEP
                     SWRGVPA"
     gene            complement(24451..25479)
                     /db_xref="GeneID:96294172"
                     /locus_tag="IE233_RS30805"
                     /old_locus_tag="GCM10010326_62740"
     CDS             complement(24451..25479)
                     /codon_start=1
                     /db_xref="GeneID:96294172"
                     /inference="COORDINATES: protein motif:HMM:NF013098.5"
                     /locus_tag="IE233_RS30805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62740"
                     /product="VOC family protein"
                     /protein_id="WP_202519131.1"
                     /transl_table=11
                     /translation="MPRQEAEAGQRTGRIGIPSIRRVDHFAFTVLDLDAAVQFFAEVLG
                     GELCYIEGPVQDQQGDWMRRKLGVHPRAVAHVAMVRVGPDTNLELFQYAAPVQRTAPVP
                     LGDPGGRRMALRVANVDAVAGRLRERDDVTVTCDAVCPTVWPGDSVRRVGFTTSWGLEL
                     QLSGSAAPLAAPRGAAPSGPAEVLGADHLALTVADLEASVRFFTEVVGARPLPLVGPRE
                     RSGVRAKLRLGPTDRIELRQYEGDGTPPAPGNADVGGSHLAFHVDDVDAAAAYLAAQPG
                     VDVMGEPETITHGPIEGNRWVYFTTPIGVQMEVLRMPDGQLPYERLTDARRASSHAFDW
                     AH"
     gene            25823..27067
                     /db_xref="GeneID:96294173"
                     /locus_tag="IE233_RS30810"
                     /old_locus_tag="GCM10010326_62750"
     CDS             25823..27067
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294173"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: salQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668902.1"
                     /locus_tag="IE233_RS30810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62750"
                     /product="sedoheptulose 7-phosphate cyclase"
                     /protein_id="WP_190028853.1"
                     /sec_met_domain="salQ (E-value: 1.7e-180, bitscore: 593.6,
                     seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.1e-66, bitscore:
                     218.6, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPDLQSTEHTFSDGLFTVGDPVTHWSVRATKQVGYEVRVEENLL
                     SVANRAILEDAVEGETVRRFIVVDSVVDELYGTRIRNYFDHHAVDYHLLVLPAGEPAKN
                     MELVLKVIDGLDTFGIDRRREPVIAIGGGVLMDIVGFAASMYRRATPWIRIPTTLIGLV
                     DAGVGAKTGVNNDGHKNRLGTYFPADRTLLDRTFLNTLDDRHIGNGLAEILKIALIKDA
                     RLFDLLEQYGEELVRDRLQRPAEPVTAEDLAASPGRAADPATEVIERAIHGMLEELQPN
                     LWEKVLERVVDYGHSFSPVIEMHALPELLHGEAVAVDMALTTVVAEQRGLLDAEERRRI
                     LRVISALGLPAWHETCTPKLLIPALRDTVRHRDGLQRLPLPVGIGAATFVNDLTEDELD
                     AAAQKLADLHWGDSE"
     misc_feature    25846..25859
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.19"
                     /tool="antismash"
     gene            27064..27822
                     /db_xref="GeneID:96294174"
                     /locus_tag="IE233_RS30815"
                     /old_locus_tag="GCM10010326_62760"
     CDS             27064..27822
                     /codon_start=1
                     /db_xref="GeneID:96294174"
                     /inference="COORDINATES: protein motif:HMM:NF014376.5"
                     /locus_tag="IE233_RS30815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62760"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_161248302.1"
                     /transl_table=11
                     /translation="MSASLEGPTVPWTAVGHTSTKASVYGVHGAEGKTYWKAFATRRQL
                     RSQSEAVEWASLPANGVSGEHRHTRTEEIYLILSGSGELLLNGGPRQVRAGSLALTSVG
                     NIHGLRNTGDGHLDWWVIETLAPATSSVLSGSPAPEGADMTQAVVHDLFEEKRVDTKGV
                     FSGPLKQVEVIDIAAGGERAVGRPGAELAVYVHAGEGVVEAPGLTETVTLVKDTCLLIE
                     AGSQSTFRATGVPLRLLVVTLAVEDEGGEK"
     gene            27819..28211
                     /db_xref="GeneID:96294175"
                     /locus_tag="IE233_RS30820"
                     /old_locus_tag="GCM10010326_62770"
     CDS             27819..28211
                     /codon_start=1
                     /db_xref="GeneID:96294175"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS30820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_62770"
                     /product="hypothetical protein"
                     /protein_id="WP_190028854.1"
                     /transl_table=11
                     /translation="MIVSRAQGDVTVRVGDRSAQWQSLIRRGMLHSECEGVEYWDLRPG
                     TRLEVRADHGVEEAVLVISGQLALFENELSSVVADAGDLLLIPHGVDGELRTGDHPATA
                     VMVRGLPAAVASRLPRRIPELPPTGR"
     gene            28423..28779
                     /db_xref="GeneID:96294176"
                     /gene="fdxA"
                     /locus_tag="IE233_RS30825"
                     /old_locus_tag="GCM10010326_62780"
     CDS             28423..28779
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294176"
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137919.1"
                     /locus_tag="IE233_RS30825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62780"
                     /product="ferredoxin"
                     /protein_id="WP_161245387.1"
                     /transl_table=11
                     /translation="MAYVIAAPCVDVLDRACIDECPVDCIYEGGRKLYIHPDECVDCGA
                     CEPVCPVEAIFHDDDLPGDWSAFRTADREVFVQLGSPGGAGARCAPVPDHPFVAELPTR
                     TALSASPSARSQES"
     gene            28776..29915
                     /db_xref="GeneID:96294177"
                     /gene="tal"
                     /locus_tag="IE233_RS30830"
                     /old_locus_tag="GCM10010326_62790"
     CDS             28776..29915
                     /EC_number="2.2.1.2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004801 - transaldolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294177"
                     /gene="tal"
                     /inference="COORDINATES: protein motif:HMM:TIGR00876.1"
                     /locus_tag="IE233_RS30830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62790"
                     /product="transaldolase"
                     /protein_id="WP_190028855.1"
                     /transl_table=11
                     /translation="MNNAMNDVFTRLAGEGVSVWLDDFQRSGTTLSELRRAVGPHGVTG
                     AVGRTDTFAELLHTSPPYRSRIRELAHGDLTAEELVWALTTQDVRTACDELRAAHERTA
                     GRDGFASVDVDPRNAWDAGATVAEARALWRTVNRPNLLVKIPATAPNLAAISTCLAEGI
                     GVNAVAIFSPDRYAQVSDAFLDGLERARAAGRDLRSIASVASFSVNCLDVEVDRELDRA
                     GSAEARAMSGKAGIANARLAYEIYEDSLASPRWRALAAAGAAPQRLAWTSTARTTPARP
                     DTSYVEELVAPDTVSVLSGATLLAVADHGEVRGDSVRRHYAESRRVLSYLSWFGISYRT
                     VVSSLEAVTLRQSAATWDALLTAVRGELDAQRRTLAPLR"
     gene            30143..31429
                     /db_xref="GeneID:96294178"
                     /gene="aroA"
                     /locus_tag="IE233_RS30835"
                     /old_locus_tag="GCM10010326_62800"
     CDS             30143..31429
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96294178"
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019886475.1"
                     /locus_tag="IE233_RS30835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_62800"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_190028856.1"
                     /transl_table=11
                     /translation="MALSPGTSRAAAFEARVPGSKSLTNRALLLAAAARSASTLRAPLV
                     SDDTVAFLNALVELGVRVERTGGDDVWSLTGLGAGPVGPARVWCADAGTAARFLPPFAA
                     AGHGDVLFEATDQLTARPVAPLAEALRQLGADVTTGPDGRLPLRVRSQGLDGGTLSLDG
                     ALSSQFLTGLLMAGPLMRTPLVLTVHNLVSRPYVAMTTALMRHFGADVAGEDDVFTVGT
                     GGYRGADLLIEPDASTASYFFAAAAATGTSVTVTGLGTGSSQGDLRFVEVLKLTGAHVQ
                     STPEATTVTGTGQLRGGFTVDMGDVSDTFMTLAALAPLADAPITIRGVGHARLKESDRI
                     AAVERNLGALGIHTRAGRDWITVHPGRPAPARIACHRDHRIAMAFSVLGLRSEGLTLDD
                     PDCVGKTFPGFHEELHRIFPQHTARRGHR"
     misc_feature    complement(30172..30181)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 ccgcgtcatg atcgcggcgg ggccccggtg gtgggggctg cccccggagg cggcccaggt
       61 gatcgacacc ggggcgtccg ccgcggtggt ggggctcttc gcccatgtcg ccacggtgaa
      121 gcgggccccg gtcctgttcc tgtgcgcggt caccccgacc gtgctcagat ccatccagaa
      181 gccgaacctg gcgggccgcg agcacctggt ggccatcacg gtcgccgtcc tgctcggcct
      241 tctcgccacc cgccgcgatc ccgcgctgcg cgacggtccg ggcctggcct gagccgggcc
      301 cccgacctca ctcgtcctcg ttgccgcccc gcgtgacggc caccacgttg gccacatcgg
      361 cgaaccgggc ggtgaggacg gccggatcgg cgcggcccac cgccgagatc agcacctccg
      421 ccggatcgcc ggtgccgccc gcccgcagca tctggagccc ggccacgctg aaccctgcgc
      481 gctcgcactg ttccatgagc tcgcgcagca ggcccggccg ctgctcgtac gcgatccgga
      541 acgtcgacgg caccgagcgc atctgcggca gccggtggac gagggggcgg accagatagg
      601 cggccaggaa gtacgcggcg gtcgccagta tcgagagcag cgggagcccg gccgcggccg
      661 cggcgcccac ggccgccgtc agccagatcg tcgccgccgt ggtgagcccc tggaccgaac
      721 cccggtgcac gaagatgacc ccggcgccga tgaagccgac ccccgacacg atctgcgcgg
      781 tcacccggga cgggtcgagc tcgatggtcc ccgcgctcag tacgtcaccg aacccgtact
      841 tgctgaccag ggtgaacagg gccgacccca cgccgaccgt ggtgtacgtc cgcagccccg
      901 cggccttctg gcggatctcc cgttcgaggc cgatggccgc ggagagcagg aaggccagac
      961 cgaactcgcc cgcctgcacc cagccctgcc cactcggctc aaggaccccg gccgccacct
     1021 gcaccatccc gtgccccttc ccactcgggc cgcgccatca cacgaacagg ctctccctac
     1081 ccatacagcc acattccatg acgccctgcc cggtcccgga gcccccggac ccggtcagct
     1141 accgctcagc gacagcgcag tgccgcgtac atgtccagct tgtgctccag gcgcgagagg
     1201 tcgcggccgg tgaggacctc gatccgctgg atgcggtagt ggaccgtgtt gacgtgcaga
     1261 tgcagggagg cggccgtgcg cgcccacgac ccgttgtgcg cgaggaagga ctccagggtc
     1321 tcccggagca tctgcgagga ggtgtgggcg tcgtcggcca gcggcccgag gaccttgtgg
     1381 tggtagatgg tccgtacgtc gtcggggatg ccggcgagca gcccctccag cgtgccgagt
     1441 tcgtccacgg cggccacacc ggccccctcg ggctcccgcg tacgggccgc ggccagcgcg
     1501 taacgggccc cggtcaggct ggagttgagc cggtcggggg tgtcgacctg ggcgccgacg
     1561 ccgacatgga gcgggaccag aggctcgcag gcctgcacca cgcgccacaa gtccctcagt
     1621 ttcagggcca cttcggaccc gccctgcacc acggccagca cctctccatg ggggaggcgg
     1681 ccgagcgcga aggggcggtc gggggtgtgg cggagggcct cggccagggc gtcggccgcg
     1741 gcggcctggt cgccgtcggc ccgggcggcg gcgccgatca catggaacgg gccgtcgggg
     1801 gaaagcccgc aggcggtcag ggcgccgttc agcgcgggca ggtcggtggc cggtgcgtcg
     1861 acgagccgga tcagctcgcc ggcccgccgc cggatctcgt tgcgcgcgcg gtcccggcca
     1921 tagcggtggc cggcgagcac gtccgccgtc tcgtgcagca gacgcggcgg cacggcagcc
     1981 gcgtccgcga ggtgcagatg ccagctgtcg tacggcgagc tgtccgtgtc gatcagcagc
     2041 gtgaggccgt cgggcgcgcg gcgcagcagg tcgcggccgc gctgggcggg gatctccggg
     2101 gccccggggg tacgcgccac ggtgcgtccg gtgggggtca ggacgtagca gtccggcgtt
     2161 ccgacgtggg cgagggcccg gtcgagcagg acgtccggct cggccccggc ccgtacgagg
     2221 tcgctgagct cgctgcggac gttgtcgggc agggcgtggc ggtgcgaggt gggccgccgg
     2281 ctgaggtcgc cccactgacg caggtagacc gcctcggtga tggcacggaa attggtgcgc
     2341 gagggcacgg cgagcagggc gatgccgttc tcgcggcagg accgggtcag ttcctcgggc
     2401 acgctgccgt gtgtctcctc accggccagg agcgcggccg ctccggcggt cacgagcgcg
     2461 gagacgaagc ggctgatctt ctcggacccc ttctccgggg cccaccacac gagaccgctc
     2521 agcacgacct cgcccggccg cagaaaacga gtcgggtcct ccaggtcggt ggcggtcacc
     2581 ccggtgatct cccggaggag ctgctgctcc tcgccccaga gcagttccag atccagggat
     2641 tcgagacgca ggaggtcttc gacgtgcatg agtggctcct tggtgcgggt gccgggttcg
     2701 taggcaccag atccgcattc accaggtgaa tgcgagtttc tgcatcgtag atgcaaggag
     2761 agagggccga aacacctctt ggttgatcct ccagagcggg cacgctcctc tggtggtttt
     2821 ccgtgtgccg caccagtcgc gcccggcacc ggtggcctgc ttcactcagg gagccgcccc
     2881 acgccgccga tggccccatc tcccgggcac ctgacgggag ttggggcgag ccgctttccg
     2941 tgccggcgac ttccggcccc tgccgtgcgg gcgtctcggc gggagggggc gccggggccc
     3001 ggcgccccga cggctacgcc gtcactcgcc gcgggggcag tcaggcgcgg ggcactgagg
     3061 ggggcacggt gcggccactc ccccctcagc gctgcgcttc cgcccccgca tccatacggt
     3121 ttcgcgcggt cctgcgcggc cttacgcgga cgtcacagcc ccgagccgcc gctcacgctg
     3181 atccactgcc cggtgatcca gcgcgcttcc tcggacacga ggaaggcgac cgcgtccgcg
     3241 atgtcggccg ggcgtcccat ccggttgaag acggagtacg cggccagccc cgccgcggcc
     3301 tcgggcgact ggcgcagcgc ggcgttcatg tccgtctcga cgaagccggg ggcaacggtg
     3361 ttgacggtga tgccgcgact gccgacgtgc ttggcgagcg cgagcgtgaa gacgtcgacc
     3421 gcgcccttgg acatcgagta cgcgatggac tcggggaagg cggtccgggt caccgccgag
     3481 gagacgttca cgatccggcc gccctcgcgc atccgctcca ggccgtactt ggtgaggaag
     3541 aacgggcccc gcgcgttgac cgtgaacatc tcgtcgaagt gctcctcggt ggccgcctcg
     3601 atgtcgccga gcggacctat cgcggcattg ttgacgagga tgtccaggcc gggcccgacg
     3661 ccgagctcca cgagcgcggc gtcgaactcc cggtagagca cgcgggcggc gtcgggccgg
     3721 cgcagatccg cgccgaccgc gaaggcggcg cccccggcct cccggatctc gtccacaacg
     3781 cccagggccg cgtcttcgtt gcccccgtag tggaccgcga cggtggcccc gtcggcggcc
     3841 aggcgctgcg ccacccctcg gccgatgccg cggctcgccc cggtgaccag cgcggtcctg
     3901 cccttcaacg cacccatgac ggtccgtccc cccctcgcgt ctcactgacg cgtaccgata
     3961 cgcgctgtca ggcacagcgc gtactgcttc gtcgaactct tccgcccctg cggaaaatcc
     4021 cgtgtgcgag cgtcagccgc ccgcgctcct ggcctcgacg gcgaccctgt actcggcgta
     4081 gagacgggcg ccgcgctccg gcgaggtgtc gagccggccc aggaccccgg gcaccgcgat
     4141 gctgggcagc accaggtcgt agagcaggga gacccgctcc tccaggtcgg acatctgggt
     4201 gctggcctgg gacatgagct gggtgccggt gaacgccgcg accatcgtct gggcggtccg
     4261 ctccgggtcc acgtacggca gcacctcgcc ctgctccttc gcggcggtca gctgctgcgc
     4321 cgtcagcttc acccagtcct gccagggctg accgaagaac cgctgggcgc tctggtcggc
     4381 cgcgatgcga gcggcaccgc gcaacagggg ctcgcgcggg agccgatggg cgaggaggag
     4441 ccccatgtcg atgaacgact ggaccttgac cggctgctcc ggcggcggct cggtcaccgc
     4501 gtgctccagg acgccgcgcg ccaggtcctc cttggaggtg aagtggaagt acagggcccc
     4561 cttggtcacc tgggccctgt cgaggatctg catgatggtg gccgactcgt agccgtgctc
     4621 ggcgaagacc gtggccgcgg cttcgagtac cgcgttgcgc gtccggatcg cacgttcctg
     4681 acgggccata caaggtctcc tgagggtcgc gggacaacgg accgggtccc ccaaaaaccg
     4741 gatggtccgt attgtaggac actctgcgcg ccgcatgcca ggggtgattt gctggccacc
     4801 catcgggccg atcaccggcg accggcaccc gaagacggcc gcaaagcggc aggtccggcc
     4861 gcactcacgg gcgccgaccg cgtcaggatc gcgtcacgaa cctgttcacc cgcccgacac
     4921 agaaccggat ggtcagtatg ttaatactgt agaagttgga cacagggact ctgactatcc
     4981 acgatggccc gggggggcac atgatcgaga tcgaccgaga cacccacata cagaccactt
     5041 cgacgttgct cgggcacatc ccggcactcg gtcgcccgga cccggcgata tcggcggcgt
     5101 tcgcccatcg agcggccgcc gaggacgtac tggtcgccgg ctggcggcgg cgcagcgaca
     5161 ccgtcttctc gatcgcggtc gactggtcga agcagcacaa cttcttcgcg cccgcccgag
     5221 ggagcgcgca ccaccacatg ctgatcgcgc agaccctgcg ccagatcggc ctggggctca
     5281 cccacgccgg actcgatgtc gccgccggaa cgaatcactt cctcctggac gatctgcggt
     5341 attccgcgga tccccgccac cgtacggaca ccctggcccc ggtgcgcgcc gaggcggagt
     5401 acacctggac cgggcggcgc agtctgcggg tgcagatcag cctccagcag ggcggcaccc
     5461 tgttcgtcac cagcagttcc cacttcacct gggtaccgga cggtgtctac cgcaggctgc
     5521 gcggcgacta tctgacggcc cgtccccgtg cgtgggccac gcccgtggag ccttccgtgg
     5581 tgggccggca ctcccccgac gaggtcacgc tcgccgacac gggcgtaccg caccgctggg
     5641 agctgatcag cgacaccggc cacccggccc tgatcgacca cgcggtcgat cacgttcccg
     5701 ggctcgtgct ccttgaggcg gcgcagcagg ccgcgtacgc cttcgccggg tcggacggct
     5761 tcaacccgct gtcgacggcg atccaggccc agcgctacgt cgagttcgac gccccgtgct
     5821 tcgtcgaggc acgggccatc ccggcgtggt ctccgggtgc cctcgcggtc gaagtcaccg
     5881 gcatccagcg cggcgaagcc acgttccggt gccagatcca ggggaccccc gcacacgagt
     5941 gacgaccgcc gtgccgccga ggggccgcgg ccgcgaggcc gcggtcccct cccgcgtccg
     6001 cccactcagc cggccgcccc tgcgggggcc cgcccggcgg acggcacggc cggagccggg
     6061 gcgcccacca ggaccggcag ttcctggtgc ccgttggaga tgaacgacgc caccgggcgc
     6121 agcgcgccgg aggggacggc gagggacagg cccgggaacc gctcgaacag cgcggaaagc
     6181 gcgatgacgc cttccatccg ggcgagcggc gcccccaggc agtggtgcac accgtggccg
     6241 aaggccaggt gcgcgcgccg ggagggccgg gtgatgtcga accggtccgc gtcgtcaccg
     6301 tgggtccccg gatcgcggcc cgccccggcc accgagagca cgatcgcctc gccgcgggga
     6361 atgaccacat cgcccaggtc gatgtcctgg acggcatagc ggagcatcag gttggcggcc
     6421 gccggctccc agcgcagggt ctcctcgacc acgtcctccc aggacgcccg tcccgccagg
     6481 accagttgga gctgttcggg atgggtgagc agggcgtgca cggcgtggtc gatgaggttg
     6541 accgtggtct cgtagcccgc ggacaggagg tggacgaggg tgtcgagcaa ctcctggtcg
     6601 tccaggggcg cctcgtccga ctgctccagg gtctcccgct gcctgaggac gagcccgctg
     6661 gtgaggtcgt cgccggggaa ctcccgcttg gctgccacga gttcgtgcag gatgccgtag
     6721 agctcggcgg cggcccgccc caccgccgcc gcatcggccg aggtgtcgaa gaggcagtcg
     6781 aagatcgcgc agagctcgtc gcgacgctcc ctcggcactc cgaacaggtc gcagatcagc
     6841 cgggccggca gcggcaccgc gaaccgggcg cgcaggtcga ggggccggcc cgcgggcagc
     6901 tccgcgatct cgtcgagcag ctcggccgcg atgcgccgca cgaccggctc cagcgccttg
     6961 gtgcggtgcg cggtgaaggc gctcgacacc agcttgcgca gccgggtgtg ttcgggcccg
     7021 tacgccgtga acatgctccg gatcgacacc cacatggcca gtgcccagtc ctgcggcacc
     7081 tccccgttgg tccaggccgg ccagtgccgg acggcgtcct tggagacgtc gggcgaggcg
     7141 agcaggcggc gcatcgcctc cgggtcggcg acggcccagg ccggcacccc gccgggcagc
     7201 tcgatccgga cggccgggcc cgcacggcgg acccgctcgg cctcaccctg gatgtcccgg
     7261 ccggccgcgt ccatcctgaa cgggcattcc tgcatgttcg gcatccttct ctctcgcatg
     7321 gacagtgctg tacgcggctg ttcgccatcg gcaccgggac ggaccgtgtc cgggcggccg
     7381 gcaccgcggg cgcggaggca gccgggcgta cggaacccct gggcggcggg acgcctggca
     7441 gctgatcggc cgggccggga ccgccgagcg ggccgccgtg agactgtcac atgccgcggt
     7501 ccatgatcat caccggccca tgacgatttg atgaactcag gccggtggca ccggacctcc
     7561 gcccggaacg agggcgtcga cggtgtccgc cgcggctatc cggggcagca gcagctccca
     7621 gaatccggtc agcatgcgct gcgagaacca ctcccgctcc tcccggccga gcagtccgta
     7681 gcccgtcatc acggccatga tcgtgaccgt cacgtcgccc ggcaccacgt cgtcgacgag
     7741 cgcgccctcc tgcgccgcct cgtcgacgaa gcggcgcaca caggtgtgcc actcgcgccg
     7801 cagatcgagc ccggactccc aggtgaagtc ggcgttgagc tggaagcccg cgcggaacac
     7861 gatgtttccg cgcagcaggc gcagcacccc gtgcgaggcg tccgtcagcg cctgcagcgc
     7921 cgactcgcgg ctgcggtacg cctcgcgcac cacggaccgc agggcctcgg tcgcgtcctc
     7981 ctcgacggcc tcggcgagcg ccgccttgtt ggcgaagtgg aagtgcaggg ccccggtgct
     8041 gacaccggcc tgcttgctga tgtcgctcaa ggtcgcctgg gcgtacccgt accggtcgaa
     8101 ggccacggcg gccgagcgga tcagatcgcg gcgggtggtg accgccctct cctgctttgt
     8161 caacggtcgg ctccctgccg gctctgcttt tcatacctgc cgctgggccg caggcccccc
     8221 gtgcggacaa ataaaccgac caagcggtgt tgttctaaca tcgtgacgtg ccctgcttcc
     8281 cgaaggggca accgcgacga gcacgaatgc ctccgggcat ggggagcagc gtacgccgtg
     8341 gatcagaaaa aaaccaacca tgctgcatgt attcgcgacc ttgtgccaca gagcgccccg
     8401 gagcccggag gcgtttgttc tcggttgaca aaccgcatgc acggttttta atctcggcag
     8461 agctcggaga tgtggcagag cagtccgtga acatctcagg tagtggtgat catccagggg
     8521 tggcgagtga tgcagcgtgt ttccgacatc catgtgaccg tgcccgacca acggtcgaag
     8581 gggtgcgccc agggacggtc cgggcgcccc ggcggccaac ggccggtcgg ccccgtcctg
     8641 atcgacctgg acgaactccg gttccgggca caggcgcaac accccggcga cgacgtcccg
     8701 tccccccgct tcctgcccga actcggccgc ctggccgagg cggtgaactc ggaggccggt
     8761 ctgacgcccc agggtgccgc cgcggtccgc gagcgcctgg tctccgcgct ggagcagcag
     8821 acccggctcg cggccctggc ccaggaggcc ccggaaacag ccgccaccca catcaggaac
     8881 cccgtcttca tctcgggact gcccggcagt ggcgcgtcga tgctccagaa cctcctggtc
     8941 gagcatccga gcgtggattc gccgaccttg tgggagatgc tctacccggt ctctcccggc
     9001 gcgggctccc ccggccggcg catgctcatc ggtcaggccc gcgcccatgt cgaggcgtcc
     9061 cgccacccgg tgcggcaccg cacggtggga cggttccgcg aggcgacccg ccccggcggg
     9121 tgccaccagc tcctcgccaa cgcgttccag agcccggtga gcgggatgta cctgcgcatc
     9181 cccgagtacg tgagagaact ggaggcggcc gatctgaccg ccgcatacgc ctttcaccgc
     9241 gagcagttgc aggcgatcac ctcacgcata ccggtcgcct cgctcgtcct gcgagcgcct
     9301 ttccacgccg cccgcgtgga cgacctgttg cgcgtctacc ccgacgcccg gatcatccgg
     9361 gtgcaccggg acccggcggc actggtcacg atcaccgccg gcctctccgc cggactgcgg
     9421 cgcaccacct catcgcgggt ggccccgaag gaggtgggcc gcgagtgggc cgaccacatc
     9481 gagcggcacc tggcgcggac atcgcaggcc ggccgacggc tcggacccga ccggctgctc
     9541 gacgtgcgcc acgccgacct ggtcgccgcc ccggccgcca ccgtccggcg cgtgctccag
     9601 ttcatcggcg tcgagccgac ccccgcggtt ctggacaatg tcgagtgcct cgcacgggcg
     9661 acggccgcgc ccacgccgaa cgcgcaccgg ttccaggcgg acgacttcgg cctgtccacc
     9721 gacgagttgc gggagcgatt cgcctcccat atcgagacat acgccctgta aggacccgca
     9781 gaggccccgc accaccgctc accacgcgcc gcgctcctcg cgccttcccc gcacctcccc
     9841 gcgcatcgaa tcagccgacc ttcccgcatg gcttgtcaat gcatgcagga acattaacat
     9901 tgggtatcaa cacggggact gcgacgacaa gtgtggagat cagcgtatga ctgcaggtcg
     9961 tggacggcgg gacggtgagg tcgagctctg gcggcagttg acggtgctca ccagtcgcat
    10021 cagcaacacg ctggacaagc ggctgcagcg cggtcatgga gtcagcgtcg ccgagtacac
    10081 cgcactcgtc gtcatgcggg acaacgcgaa gtccggcggg gtgcgcatgc aggacctcgc
    10141 cgaggccgtc gggctgagcc agtccacggt gagccgactg gtcgcccggc tggagaacga
    10201 gggcctcgcc ggccgtgtca tcagcgagga agaccgccgc gtgatgtacg cgcagatcag
    10261 cgagcagggc acggcggtga tcgcggacgc cgccgcgacc ttccagaagg aactcaccac
    10321 ggccctggac gtggcctcgt tcgacgagca gaccgcgtcg ttggtcgccc gtctgcgcca
    10381 caaccccgcg acggccggcg gctgagccgc tccgttcccc gtcacgtagg gcgcgagcgg
    10441 gcgcagcaat gagcccggcc ggcctcagcc gaccgggctc gggcccgacc cttggatccc
    10501 cgctgtccta cgcgtacgtg tagaagcccc ggccggactt cttgccgagc agcccgcact
    10561 ccaccatgcg cagcagcagg ggcggcggtg cgtagagggt ctccttggtc tcctcgtaca
    10621 tcgcctgcgc gatggagacc gtggtgtcca ggccgatgag gtcggcgagt ctgagcggtc
    10681 ccatcgggtg ggcgcagccc aactccattc cctggtccac gacttcgggc gtggcaaggc
    10741 cgctgtcgac catccggacg gccgacagga ggtaggggaa cagcagggcg ttcacgagga
    10801 agccggcccg gtcgggagcg ctgatcacgg tcttgccgag cacacccgcg acgaagtcgg
    10861 cggcacgggt ccgcgtcccg ggctcggtga ggacggagcc gaccagctcc accaggggca
    10921 gcaccggcac cgggttgaag aagtggatgc cgatgacctt gccgggccgc cgggtggcgc
    10981 gggcgagccg cgcgaccgac agcgacgagg tgttggtggc gatgatggcg tccttcgaca
    11041 ccaggacctt gtcgagcgtt gcgaacacct cggccttggc ctgctcgtcc tcgcggacgg
    11101 actcgatcac cagctgccgg tcggccagtt cgccgaggtc cgtggtgaag gagatccggt
    11161 cgagggcggc ggcccggtcg gcctcggtga tgcggccctt ggcgacaccg cggtcgaggg
    11221 acgcgcggat cctggccgcg ccccggacgt gcgagtccgc tgagctcacg gcgacccgga
    11281 cgtcgcgccc ggccctggcg cacagctcca cgatgcccgc gcccatggtt ccgcatccga
    11341 cgacgcccac ccggtcgatc cgctcggcgc cggcgtcgag ccccgcgccc tccttcggtc
    11401 cggacaccag ctccaccacg gcagttgtgc ctctctcgtc catctcggtc aaccggccag
    11461 tgccggtacg cggggagcca gcgggctgag gcgctcctcg ccgatgcggg cgcgcagctc
    11521 cgggtcggtg atgccgagcc cgggctcggg ggcaagggcg agcaccccga cctttccggt
    11581 gtgccggttc gtctggacga gccgggcggc ctcggcggcc tcggcgagcg gataggtggc
    11641 ggacagcacg ggcgacagca tgcccagctt gaacagccgg ttgcactccc actgctcctg
    11701 caggttcgcc gcgtgactgc cgatgatccg cttcaggttc atccacagat agcggttgtc
    11761 gaactggtgg gtgtagccgg tgctcgatcc gcaggtgacg acggcaccgc cgcggcgcac
    11821 cacgaagacg gagatgccga aggtggcctg gccgatgaag tcgaagacga cgtgcgggtc
    11881 ttcgccgacg cgctcgcgga tggcccgccc gagccgcttg ccgagctcga tggtcttctc
    11941 cgggctcggc gcggcatcgc cgtccatgcc gatctccgtg cggtcgatga cgacgtcgca
    12001 gcccatccgc cggaggatct cggccttggc ctgcgagctg accaccccga cggggatgcc
    12061 accggcgttc ttgaccaact ggacggcgaa cgcgccgagc ccgccggtcg caccccagat
    12121 gagcacgatg tcgccctgct tgatgcgggc accccggtcg ctgatcagca tgcgatagga
    12181 agtggcggcg gtgagcatgg tgctcgccga ctcctcccag gtcagatggg cgggcttgga
    12241 gaggagctgg ctggcgcgta cgacggtgta gtgcgcgagg ccgccgaagt tggtctcgta
    12301 gccccagatc cgctgctcgg cgcccatcat cccgtcggcg tgggtcgccg gctcctggtc
    12361 gtcgacctgg acgcagctga cgacgacgtg gtcgcccgcc ttccagcggc ggacggcgga
    12421 gccggcgcgg accaccaccc cggaggcgtc ggagcccagt acgtgatggg gctggtcgtg
    12481 ccgggcggcc caaccgccct gctttccgag cttgttgagg aaggcgaagg tcgacacggg
    12541 ctcgaaggtc gccgaccaca cggtgttgta gttgatggag ctggccatga ccgcgacgag
    12601 cacctcgtcc ggcgcgagct ccggcatcgg aacccgtccg acgtgcagcg acttgcgcac
    12661 gtccttgtcg tccacgccgc ggaacatctc cacgtcctcc gcccgcgtgt ggacggccgg
    12721 atagtcgccg ggcagcggct cccgctccag ctgtgcgggg gtggcgccgt tcagaacggc
    12781 gtccgccaga gaatccatgt cagtccttcg tcgtcgacgc ggggtgaggc gtggggtcgg
    12841 gcagggcggg gttcgatgcg cgggcggaac ggcaggggga gggcacgttc cgcccgcgca
    12901 gtcggatggg ccgcggccgg cgcggccccg ggtcaggaga cgagaccgcc ggcggcggcg
    12961 aggtactggc ccgtgatgta cgaggcgtcg tcgctcgcga ggaacgcgac gaccccggcg
    13021 atgtcctccg gctcaccgat gcggccgagc ggcatcatct gcgcgaaggt gtcgtactgg
    13081 tccgcgatcg gggcggtctg gtccgtgcgg atcaggcccg gcagcaccga gttgacggtg
    13141 acgccgcggc cgccgacctc gcgcgccagg gcgaggccga gctgctcgac ggcggccttg
    13201 gtggccgtgt agacaccggt gcccgcgaag gtggagtggg tgtagccggt ggagatgttg
    13261 atgatccggc ccccgtcgct gacgtgggtc gcggcctggc gcagcgagta gaacgtgccc
    13321 ttgaagttga cgtcgacagc gcgctcgaag gtctcgtcgt cgacgtcggc gatgttgccg
    13381 ttgccggcga tgccggcgtt gttcacgacg atgtcgagcg aaccgaaggc gttcagaacc
    13441 tccttgtaca ggttctcgat ctcgtccttc ttcgcgaagt cggcctgcag ggcgatggcc
    13501 ttgccaccgg ctgcgacgac cgcgtcgacg acctcctgcg cggcggcggc gttgctctgg
    13561 tacgtcacgg ccacgtcggc gccgtccgcg gccagacgca gcgcgacagc acggccgatg
    13621 ccccgggagg aggcggtgac cagggcggtc ttgccctgca ggcgcttggc ggtctgggtg
    13681 gtcataaggg tcataccttt cgttgttttc ttccggtgct gcttacgcga gaatttaatg
    13741 cacattcatt tcatgcgcaa gcaagttctt ggggggcgag atgttccgcc cggggtgtcg
    13801 cgcgcgggtg gcgcgacgag ccggtccggc tcaggaggga agctcgacgg acagggcgtg
    13861 cgagaaggtg ttccgcgggt cccatttggc cttggcctgt tgcagggccg cgtagttgcc
    13921 cttgtagtag agctgctgcc agggcgtgcc cgaggcgttc caggccgggt ccttgacgtc
    13981 cgcgtcggcg tagttgatga acatgccgtc ggtgacgccg ttcaggccgg gcacgccgcc
    14041 ggtctcgctg tacaggtcgc ggaagaactc ccgcacccag gccaggtgtt tggcgtcgtc
    14101 cgccgcgtcc gtccacagga ccgcggtctg caccttcagg atcgagtccc gctgcgccac
    14161 cgcggtgtcc gcgggaccca cctcgttcac cttgccggca taggccgaga tcagcatcag
    14221 cgcggccgga tactcgtagt cggtgcgcgt caggtgcttg tacatcgcgt cgagctgcgc
    14281 ggcggtgaag ttcttgcgct ggtaggcggg cttgcccttg aaacggaaca gcgggtcggg
    14341 cccggtgaag ccggaccact gggtcgcgtg cagccacggg accttgcggt ggtcggccac
    14401 ttgcgcggtc accccggtgc ccgcgccgac gtacgcgacg aagtcgtcga gcatctgctc
    14461 ggcgccgggt gcggaggcct ccacctgcac ggtcagcgag atcgcaccgg ccgcccggtg
    14521 ggacggcttg agctcgctga acagcgagag ctgggccgag cccggtgcgc tgttgtcgat
    14581 gtgccactgg gcgtagttct tcatcagccg gccgaagccg tccttggtca ggccggccca
    14641 cggccagttg accgtggata tccacacctc cgacggggcc ttgggcaaca gcttcgacgg
    14701 atcgctgccg gtggcgcccg gcgcccgcat ccaatagcgg gtcaccacac cgaagttgcc
    14761 gccgccgcca ccggtgtggg cccaccacag gtcgcggttg gggtcgctcg cctcgcgcgt
    14821 ggcgacgacg gccttggcgg ttcccgtcct gtccaccacg acgacctcga cggcgtacag
    14881 gtgatcgctg atcagcccgt acctgcggga cagcgcgcca tagccgccgc cctggatgtg
    14941 gccgccggcg ccgaccgtcg ggcaggcacc gccggggacc gtgacgcccc agcccttgaa
    15001 gagccgctcg tagacctggc ccagcttggc gccggcctcg atgacgaagg cgttgcggcc
    15061 ggagtcgaat ccgacggcgt tcatcgcgga gaggtcgatg acgaccttga cggctgcgtt
    15121 ggccacgaag tcctcgtagc agtggccgcc gctgcgtacg gcgatcttct tgcccgcgct
    15181 caccgcgctc tgcaccgcgg cgacgacctg gctggtcgag cccacgaggc gaatgctctc
    15241 gggatttccc tcgaaccgct ggttggtgcc tcggcgcaga tcggcgtagc ggctgtccgt
    15301 tgaggcgacc gtgaccggcc cgaaggcggt gctgcccgtg ctctcccccg cggccgtggc
    15361 ggcgggcggg gcgaagatgc ccgcgccgag gccggtcccc accgctgcga cgccgacgcc
    15421 ggtcgcggtg cgcttgacga accttctgcg tgtcaccgtg ctggtcactt ctgagtcctt
    15481 acgttctctg gcgggcggcg acgaacgccg ccgggggctg tacgcaagtg gggggctgcg
    15541 ggggcggtgg ccgccccggt caggggggtg ctttcgggcg tccgggacgc gcggcgatcg
    15601 gcgcgccact cgcaccaggc gatggagcac ccggcgaggg tgaggaccgc ggcggccagg
    15661 aagacgctcc tgagtccgtg tccgaggtcg agcacccggc cgccgagcca ggagcccaga
    15721 gcgatcgcgg tctggacgga cgcgatgctc atcgcgacgg cgagtgtggg ggcgcgcccg
    15781 gagacggagt tgaggatgcg ggctccgagc ccgggattga gggcgaagaa gacgatgctg
    15841 aacacgacca gcgcgccgac ggcggcgacc ggctgggggg cgacccccgc gaaggccacc
    15901 aggaccaccg tgagcacggc gagcagcgcg gtcagcgacc ccatcagggc ccggtccgcc
    15961 agcttgccgc cgagcgcacc gccggccagc gaaccgaggc cgaagaggaa gaggagcagg
    16021 gtcacctgat gacccgagaa gccgctgacc cgctcgagca gcggggtgag gaacgtgaac
    16081 gcggtgaacc cgccacccat gccgaccacg gtcagcagca gggccacccg caccctgcgg
    16141 tcgcgcagca ccgagagttc ggcggccact cctcccccgg ccccggcgga ggtggcgggc
    16201 accagcagga cgcaggcgag cagggcggtc aggctgagca ccgtcacgcc ccagaaggtc
    16261 gcccgccagc cccactgctg ggcgagcagc aggccgagcg gcacgcccac gatcgtcgcg
    16321 aggttgacgc cgatgatgat gcgggccacc gctgacccgg acttccgcgg tcccgcgatc
    16381 tccgccgccg cgatcagggc gagcgcgaac agcgtgcagt ggctgagcgc ggacagtacc
    16441 cgggccgtca tcaggacgcc gtagccggga gccagcgccg cgagcacatt gcccgcgacg
    16501 aacagggcga gcagcccgat caggaggggc ttgcggggca gccggctggt catcagcgtg
    16561 accagcgggc cgccgaccac gatggccacg gcgtaccccg agaccagcag ccccgcctgg
    16621 gaaagcgaga catccaggtc cgtggagagc tgcggcagca gaccggcgat gacggactcg
    16681 gcggttccca ggctgaacac actcagcacc agggcgaaaa ggggggccgg catggcatga
    16741 ctccacagag gacgatgagg ggctgacccg tgaatcagcg caggtggacg gggagttcgt
    16801 agagtccgcg gatgagcagc ccctcgcgcc agcggagcgt gtcgacgggg gcggcgagcc
    16861 ggatggcggg gaagcgccgc accaggctgc cgacggcgat ctgtccttcc atccgggcca
    16921 ggggcgcgcc gaggcagtag tgcatgccgt ggccgaagac caggtgcccg gcgtcaccgc
    16981 gggtgatgtc gaaggtgtcg gggttctcga agcggtccgg gtcgcggccc gccgagccga
    17041 gcgagaccag gacgggggcg ccggcgggga cgcggacgtc gtcgaagtcc aggtcctcca
    17101 gtgcgaagcg ccaggtggcg acctccaccg agccctcgta gcgcaggaac tcctcgatcg
    17161 cgctcgtgat cagcgacggg tcgttgtgca ggagggccag ctggtccggg tgctgcatca
    17221 gcgccagcat gccgttgccg atgaggtgga ccgtggtctc gtggccgccg atgagcatga
    17281 ggaaggccat ggcggtgagt tcgccgtgcg acaggcgctg gccctcgtcc cgcgcctcga
    17341 tcagcgcgct gatcaggtcg tcgcccgggt gctcggcctt gtgcgccacc aactcgtcca
    17401 gatacgcgcc gagttgaccg gccgccttgc ccacacgggc gtgcccctcc tcgtcggcga
    17461 ccagcgtcga gagcgcggtg gaccagtcgt ggatgtcgtc cacatcggcc agcggaacac
    17521 cgagcagttc acagatgacc gtgacgggca gcttgaaggc gaacttgtcg agcaggtcca
    17581 ccgagccctc ggtcgcgtcc agttcggcca ggagaccgtc ggtgatctcc tggatccggc
    17641 cgcgcagggc ctcgatgcga cgcggggtga agcccttgtg cacgagacgg cgcagccggg
    17701 tgtggtccgg cgggtcgacg ttgagcagat gacgtacgag cgaggcgtcc tcgccgtcgg
    17761 tcggctgggc gacggtggcc ctccagcgct cgccgacccg gttcgggtcc ttgctgagcc
    17821 gcgggtcggc cagcgcgttc ttggcgtcct cgtagcgggt caccagccag aactcaccgc
    17881 cgtcgggcag cgacatgtga ctcacgggag cctggcggcg caaccgtgcg tacagggcat
    17941 aggggttggc ctcacccccg aagctgatgg cctccggcgt gccggccgtc gcgctaatcg
    18001 tcatcgttcc ctccccaaga tcgatacgaa cgagagtcag taaaaaacct gcgatccggt
    18061 ttgtcaaccg cgaccatcgc cgcaccgacc cgccgaaatc gcggctaaaa acctacaaat
    18121 acgggcaaca ccagcccggc tgtaaggcac atagggaacc aatcccccta ccaagaaccg
    18181 cacagccggt tcgataatgc gttcctgcct tcgctaccgg gtcccggcaa gctcgctctg
    18241 cccggcctcg gccggcgtcg cgaccttcgg tccgctcgcg atccggtccg cccgcggtct
    18301 gctccagcgc cgcatcgcgg gccgctccac cagggcgtac agcgcccagg cgaccagcac
    18361 gctgagcacc aggcccccga ggagcagcgc gattccggcg ggcgtgctcc agccctgcgg
    18421 attgccgagc tgcccacggc accagatcag gacgatggcg tgcacgaggt agaaggcgta
    18481 cgagatctca cccagccaga tcgcgaagcg gccccgcagt ccggtgcgcc acccgttgat
    18541 gtcggccacc gccgcggcgg ggacgagcag ggcgatcggg atgatcgtgg ccgcgttcag
    18601 gccgtacacg taagggagtt gacccgccag cgcgtagcag gcgacgaaga ggagggcggc
    18661 ggggaggaca ccgaccctga tccacttgcc gttgatcacg atgcgcgcca gcaggatgcc
    18721 caggaagaag tccagggccc gcaccggcgg cagcgcgtac acgaaccaga actggtagag
    18781 acccagcggc tgcccgtccg gcatggccgg cccgtcggtg atcacgacct gggcgatcac
    18841 cgcgacgccg atgacggccg cgaccacacc ggccacccac caccacagtt tctccaccgg
    18901 gatccggttg gcccagcgca gcagcagcgg gaacgcgacg tagaacagcg cctcacaggc
    18961 gagcgaccag ctcggcgggt tcacgctgaa cagcaggctg tagaccggga accaggactg
    19021 caccatgaag aggttggaga tcgcctggta cagctgggtg gaggtggcga cgagcagcag
    19081 cgccgccacg aaggtcacca cgtggttggg gtagagcttg gcgatccggc ggcgcagata
    19141 gcgcttgtac gtgtccttgc gccgcgccga ccaggtcagc acgaagccgc tgagcaggaa
    19201 gaagaacgag acgccgacgt ggccggcggt gatgaacagg tcgtggtaga aggacaccac
    19261 gtccttgtcg gagaagacgt tgacccagat tccgtggtgg aggaatacga gagcggcggc
    19321 gatgaaccgc atcccggtca gcgtcggaag ccgcgaactg ccgggcgcga ctggcgagtc
    19381 ggtcgttctg ggcatggggg tactgcctcc ctgcgaagaa agtggtggat acggcctcgt
    19441 cccctgcggc tcacgcgacg gacagggagg cgaagggcgc cgacgcgcac ggcttcgctt
    19501 gaccggtggg atgaccctag ccacacatcc tatgcatctg caagcaattt ggtgaatctc
    19561 aaactggcag tcctagcggc gagttgatgc cgaaggggcc cattgcacga gcatgaccag
    19621 aggagacgta tgcttccagg tgcaagcttt tatcaggttc atccaccaag gagatccgac
    19681 atgcgcgcac tgaccctcgc ggagtacggc ggcccggagc tgctgaccgt ttccgaactc
    19741 ccctcccccg cccctcgggc cggccagatc ctggtccgca ccgcggcgtc cggcgtcaac
    19801 ccggtcgatc tgctggtgcg cggcggcgcc atggcggcga acatctccca cccgttcccg
    19861 ctggtgctcg gctgggacct gtccggcacg gtggaggcgg tcggcgccgg cgtcgaccgc
    19921 ttcgcccccg gcgaccgggt ggtggccatg tcggcgcagt acgccaccgg catcggcacc
    19981 cacgccgagt tcgtcgccct gcccgccgcg atcgccgcgc cggccccgcg caccgtggac
    20041 ctggtcgagg ccgcggcgct gccgctggcc gggctgaccg cctaccaggc actggagaag
    20101 ctcgccccgc gctccggtga gcggctcctg atcagcggtg ccgtcggtgc ggtgggcggc
    20161 ttcgccaccc agctggcagc atcccgcggc gtcgaggtca tcgccctcgc ccggccgcag
    20221 gatgccgaac tggcaaggga gttgggtgcg tcctcggtgc tttccgccga cgagccgctg
    20281 cccaccgcga tcgccgatgt cctcctggag acggccggca tcgcgccgaa ggtgataggc
    20341 gcggtccgcg acgagggccg ggccggatcc atctacgcgc ccgagccgcc gaaggccgag
    20401 cgcggcatca ccgtactgca gaccttcgtc gagcaggacg gcgaccagct ggcgatcctg
    20461 tccgcgctgg tggacgaggg cgtgctcacc ctgcgggtgg ccgagatcgg cgacttcgcc
    20521 ttcggtcccg aggcacaccg caggctcgcg gccggcggct cccgcggaaa gttcctcctc
    20581 accccgtgag cccaagggcg taactgccct gggaacaagg cgacttcatc acggacgagt
    20641 gcggccccgg ggattctccc cggggccgca ctcgtgttgt ccaaggtcct caccgcccgg
    20701 tgaagaccgc cttgcccgga ccgtcggcga cgaacgtgcg catgccggtc agctgatccc
    20761 gggtgccgaa aaggccctcg aacagggtgc gttcgagttc caggcccgag cgcagatcgg
    20821 tgcccgtacc cagatcgacg gcctgcttga tcgcccgcag ggcgagcgag gggccgccca
    20881 cgaactggct cgcccaggcg agcgcctccg tgagcacccg gtcccgcgcg accacccggt
    20941 cggcgaggcc gatctccagt gcctcctggg cgctcagcgc ccggccggtg aacatgatct
    21001 ccttggccct ggccgtgccc accaggcggg agagccgctg ggtgccgccc gcgccgggga
    21061 tgacgcccag cttcacctcg ggcagcccga tcttcacctc gggggccagg atgcggtggt
    21121 cggccgtgag cgccagctcg cagccgcccc cgagggcgaa gccggtgacc gccgcgacga
    21181 ccggtttggg gatgtcggcc accgcggtga acgcgccctg gagacgggcc gcccacaaca
    21241 ccatgtcgat cggctccagg cccgccatct cccggatgtc ggcgccggcg gagaacttgt
    21301 cggggccgcc gtagagcacg accgccgaga cgtccctgcg gtccgccgcc tcctgtgcgg
    21361 cttcgcgcaa ctgcgcctgg gccgcgtggt ccagggcgtt gaccggcgcc cgggacagtt
    21421 cgatggtgcc gatgccgtcg gccaccacga gccggaccgc gggttccacc tcgttcacgc
    21481 ccacagcaga cctccgttga cttccagcac atgaccgttg acgtacgagc tgtcctcgct
    21541 cgccaggaac accgcgccga gcgccgcctc gtcgagcttt cccgcgcggc ccagcgagaa
    21601 gcggtggtgg taggcctccc acaccttctt gttctgcgag agctcgcggc ccattccgtc
    21661 ctccaggacg cccggcgcca ggcagttgac ctggatgccc ttgcggccca gctcgatcgc
    21721 ggacaccttg gtgagggtct cgatggccgc cttggtcgcc gagtagcccg ccgcgccgat
    21781 ggcgacccgg ctcgccatgc tcgacgagac cgtgatgatg cggccgccac cctgcgggat
    21841 cattcggcgg gcggcgctct gcaggctgta gaaggcgccg ttgaggttgg tgtccatcat
    21901 ggaccgccag tcctcgggag tgaggcggtc gaccttgccg tcgcggttca cccccgcgtt
    21961 ggcgaccagc acgtcgatcc gcccgtaggc cgccaccgcg gcgtccatga gcccgtcgac
    22021 gctgtccggg tcggtcacat cggtctcgtg gaacaggacc cggtccggca actgattgat
    22081 caactgctgg atgtcgtagg ggttccgggc cgcgcagacc acggtggccc cctcgtccac
    22141 gaaccgctcg gcgatcgccc ggccgagccc ccgggtgccg cccgtcacga cggtgacctt
    22201 gtccttcaga cgcatgttgt gctccccctc tcagtaccag gtcaggacgg ccgcgcccgc
    22261 ggtcatcccg ccgccgacgg ccgcgaacag gatgcgctcg ccccgctcga tcggccgctc
    22321 gcggtgcgag tggcgcagcg tgaacgggat ggaggcggcg cccgtgttgc cgaactgcgg
    22381 tgcggtgagc gggactcggg acatgtccac gcccaactgc gcggccacgg cctcgacgag
    22441 ccgggtgttg ccctggtgga tgaagacccg gtcgatgtcg ccgatctcca gacgggcctg
    22501 gctcagcacg tcgtcgacgg tcttcgggat gatctggagg gcgtactcct tgaccgaacg
    22561 tccctgcatc cggaagaagt gccggcccgc ctcgcgggcc gcgtcgtccg cggtctcgcg
    22621 ggtgccgccg gccgcgacct cgacgaggtc ctccccgtcg ccgtccgcgt agagccgcgt
    22681 cgcgtggatg ccgtagccct cgggcacctc gccgagcagc acggccgcgg cgccgtcgcc
    22741 gaacagcgac acggtgcgcc ggtcgccgcg gtccatgatg ctggagtaca tgtcggcgcc
    22801 gatgaccagc gcggtcccgt tgtcgggcga ggtgcgcagc atcgactcgg ccacggtcag
    22861 gccgtagacg aacccggagc acaccgcgtt cacgtcgaag gccggcgtgc tgtgcatccg
    22921 cagcagcttc tgcatccgca cggcggtggc gggctgcggc tggtcggggg tggaggtggc
    22981 gagcaccgtg aggccgacgc gctcacggct gtgcggcgag tcggcgaaca gctcctcgac
    23041 cgcccgggcc gccatcgcgg acgtggtgac gcctgggtcg gcgtagtgcc ggccgtgcac
    23101 ccccgtccgt tcggctatcc actccggggt gaccccggtc cacgtgctga tctgctcgtt
    23161 gtcgatgacg cgcggcgggg cgtacgcacc gagaccgatg attccgacgg gcatggcccg
    23221 ctccttcgct gacttgggga tgggggtcgt ggctgaaccc gaaaggacgg ccccgggcac
    23281 tgggcggctc acgccgggac gccgcgccag gacggctctt cgaggatgtc gagcacggcg
    23341 caggtccagc tgaacccgcc gcccacaccg agcagcagga cgcgcttgcc gggtgtgagg
    23401 gcgccggtct cggtgaggtg gttgaggccc gcgaactggt cggcggggcc gaggtggccg
    23461 gtgcgccgag agaagtccca ggcggtccgg ttcaggtcct ccacgcccag cgggcgcagg
    23521 cattgacgga gcgtcagacc ggcgccgaag tgcggggcga cgaggtggtc catctcgtcc
    23581 atggagcggc ccgcctcctc cagagcctgg ttcgcggcct tctggaggcc gccctcgacc
    23641 cggcgccaca cctcgtcctt gtcgaagtcc tccaggaact gctggtggcg gcggttcagg
    23701 tcgatggggt gctcggcgtc gtgctggaag ggaccgaagg gctcgtggcc acggtgcatc
    23761 gcctccagct cggggtcggt gtaggtcgcc atcgacacga tccgggcgaa ccctccctca
    23821 cgggagagcg ccacggccgc ggccccgtct ccgtacagga tccggtcggt gcgccagcgg
    23881 tcgaagtacg ggtcggtcca caggtcaccc gcggtggaga cggcgacctt cgccgtgggg
    23941 tgggcgtgca gatagccggc ggcgagctcg gcggcgacca ggcccccgtt ggaacccgag
    24001 cgcacctcgg ccgcgaggca gcccggggcg gcgatcccct tctggatgta ggagccggag
    24061 ttccagatgt cgatgccgtt gtggaacacg acggagtacg tgaccgccgc cacgtcctcg
    24121 gggcggtatc cggaacgccg cagcgcctgc tgccccgccc gtaccgccat ctccgggatg
    24181 ctgtcctcgg gggcggcgac ggtgacggac aggtggccgc tgtgccgggc ggactcctcg
    24241 tcgtagacac cggcgtcgat ggcgtcctcg acgctcatgg tcttgggcag gtaggcgccg
    24301 gtgccggcga cgtacaggtg gtcccaccgc atggtggtgc tcctcaaggc agaagggtgg
    24361 ctgaaagaag aagaaagagc agaacggagc gggagaggcg gtggacgagc agcactggtc
    24421 gtccggcccg ggcctcgccg aagtgcgttg ctagtgcgcc cagtcgaagg cgtgggagga
    24481 cgcccggcgg gcgtcggtca gccgctcgta ggggagttgg ccgtcgggca tgcgcaggac
    24541 ttccatctgc acgccgatgg gggtggtgaa gtagacccac cggttgccct cgatcgggcc
    24601 gtgggtgatg gtctccggct cccccatcac atcgacgccg ggctgtgccg ccaggtaggc
    24661 ggccgcggcg tcgacgtcgt ccacgtggaa ggcgaggtgg gatcccccca catcggcgtt
    24721 gcccggcgcg ggcggggtgc cgtcgccctc gtactgtcgc agctcgatcc ggtcggtggg
    24781 ccccaggcgc agcttggccc gcacccccga gcgctcccga gggccgacga gcggcagcgg
    24841 gcgggctccg acgacctccg tgaagaagcg tacggacgcc tccaggtcgg cgacggtgag
    24901 cgccaggtga tcggcgccca ggacctcggc gggcccgctc ggcgctgcgc cccgcggggc
    24961 ggccaacggg gcggcggagc cggacagttg gagttcgagt ccccatgagg tggtgaaccc
    25021 gacccggcgc acggagtccc ccggccacac ggtggggcag accgcgtcgc aggtcaccgt
    25081 gacgtcgtcc cgctcgcgca gccggccggc cacggcatcg acgttcgcga cgcgcagcgc
    25141 catccggcgc cctcccgggt cgcccagcgg caccggagcg gtgcgctgca ccggtgccgc
    25201 gtactggaac agctccaggt tggtgtcggg gccgacccgc accatggcca catgggccac
    25261 ggcccggggg tggaccccca acttccgccg catccagtcc ccttgctggt cctggacggg
    25321 cccttcgatg taacagagct cgccgccgag cacctcggcg aagaactgga cggctgcgtc
    25381 gagatccagc accgtgaacg cgaagtggtc cacgcggcgg atggacggaa taccgatgcg
    25441 gccggttcgc tgcccggcct ctgcctcttg gcgcggcatg cccgcgctcc ctcccggtga
    25501 tctgcgtgac ggaaacccgt ggtcacggac gatacagatc tatgcatctg aaagcaacta
    25561 accacgagtc tcaccaggca cccaaggaag agcgcggcca ggaacagagc tctcgcgacg
    25621 gccaattgca caccgaaata aggccacagc ccccagcgcc gacatgcacc cgaggggcga
    25681 gggtgacgcc aaccacgcat taatgtgctt gcagatgcat tgaagtactg ccatagtccc
    25741 tgacgaagcg atcaagcccg cagcgtgtgg cacacgacgt cgccccgcgc ggagcagcaa
    25801 cgtcccaatc gaggagacag gcatgcagcc ggaccttcag tcgaccgaac acaccttctc
    25861 cgacggcctg ttcaccgtcg gagacccggt cactcactgg tctgtacgag ccaccaagca
    25921 ggtcggctac gaggtacgcg tggaggagaa cctgctgagc gtcgcgaacc gggcgatcct
    25981 ggaggacgcc gtcgagggcg agacggtgcg ccgcttcatc gtggtcgact ccgtcgtcga
    26041 cgagctctac ggcacccgca tcaggaacta cttcgaccac cacgccgtcg actaccacct
    26101 gctcgtcctc ccggccggtg agccggccaa gaacatggag ctggtgctga aggtcatcga
    26161 cggcctcgac accttcggca tcgaccggcg ccgggagccc gtcatcgcca tcggcggcgg
    26221 tgtcctcatg gacatcgtcg gcttcgccgc cagcatgtac cggcgcgcga ccccctggat
    26281 ccgcatcccc accaccctga tcggcctggt cgacgccggc gtcggggcca agaccggggt
    26341 gaacaacgac gggcacaaga accgcctcgg cacgtacttc cccgccgacc ggacgctcct
    26401 ggaccgtacg ttcctgaaca ccctcgacga ccggcacatc ggcaacggtc tcgcggagat
    26461 cctcaagatc gccctgatca aggacgcgcg cctcttcgac ctcctggagc agtacgggga
    26521 agagctggtg cgcgaccggc tgcagcggcc ggccgaaccc gtcacggccg aggacctggc
    26581 ggcttccccc ggccgggccg ccgacccggc gaccgaggtc atcgagcggg cgatccacgg
    26641 catgctggag gagctgcagc ccaacctctg ggagaaggtc ctcgaacgag tcgtggacta
    26701 cgggcactcg ttcagcccgg tcatcgagat gcacgccctg ccggagctgc tccacggcga
    26761 ggccgtggcc gtggacatgg ccctcaccac ggtcgtcgcc gagcagcgcg ggctgctcga
    26821 cgccgaggag cggcgccgga tcctgcgggt gatcagcgcc ctcggcctgc ccgcctggca
    26881 cgagacgtgc accccgaagc tgctgatacc cgccctgcgc gacaccgtgc gccaccgcga
    26941 cggcctgcag cggctgccgc tgccggtcgg catcggcgcc gccaccttcg tcaacgacct
    27001 caccgaggac gaactcgacg ccgcagcaca gaagttggcc gacctccact ggggtgactc
    27061 cgagtgagcg cgtccctcga aggccccacc gtcccgtgga cggccgtggg ccacaccagc
    27121 accaaggcct cggtgtacgg agtgcacggg gccgagggca agacgtactg gaaggccttc
    27181 gccacccggc ggcaactgcg ctcgcagagc gaggccgtcg agtgggcctc gctgccggcc
    27241 aacggcgtca gcggcgagca ccggcacacc cgcaccgagg agatctacct catcctgtcg
    27301 ggcagcggcg aactcctgct caacggcggg ccccgacagg tccgggccgg ctcgctcgcc
    27361 ctcaccagcg tgggcaacat ccacggcctg cgcaacaccg gtgacggcca cctcgactgg
    27421 tgggtcatcg aaaccctcgc accggcgacc agttcggtgc tgtccggatc accggccccc
    27481 gaaggagcag acatgaccca ggccgtggtg cacgacctgt tcgaggagaa gcgcgtggac
    27541 acgaagggcg tgttcagcgg accgctcaag caggtcgagg tcatcgacat cgcggcgggc
    27601 ggggagcggg ccgtgggccg ccccggggcc gaactcgccg tctacgtcca cgcgggcgaa
    27661 ggcgtggtgg aagcaccggg cctgacggag accgtcaccc tcgtcaagga cacctgcctg
    27721 ctcatcgagg ccggctcgca gtcgaccttc cgggcgaccg gagtcccgct tcggctgctc
    27781 gtggtcacgc tcgcggtcga ggacgaaggc ggcgagaagt gatcgtctcc agggcccagg
    27841 gagatgtcac cgtgcgggtc ggcgaccgct ccgcacagtg gcagagcctc atcagacggg
    27901 gcatgctgca cagcgagtgc gagggcgtcg agtactggga cctgcggccc ggcacccggc
    27961 tcgaagtccg ggccgaccac ggtgtcgagg aagcggtact cgtcatcagc ggccaactcg
    28021 ccctgttcga gaacgagttg tcctccgttg tggccgacgc cggagacctg ctgctcatcc
    28081 cgcacggcgt cgacggggag ctgcgcaccg gcgatcaccc ggcgacggcg gtcatggtgc
    28141 gcgggctgcc cgccgcggtg gcatcccggc tgccgcgccg catcccggaa ctcccgccca
    28201 ccggccgctg acctcccgcg cctcccccgg cacccggcgc cgctcggccg gtcgcaccgg
    28261 cgcacgtcga cccgccgccg acgccggccc ccggccggcg cggcacaggt gtcccaccac
    28321 cccggccccc gtacgtccac cgcccccggg gctcccccgt cccgctgccc gtacggacgg
    28381 ccacccccca cacccccgca ccgcacaccc ccaggagacc ccatggccta cgtcatcgcc
    28441 gccccctgcg tcgacgtact cgaccgggca tgcatcgacg agtgcccggt cgactgcatc
    28501 tacgagggcg gacgcaagct ctacatccat cccgacgagt gcgtcgactg cggggcctgc
    28561 gagcccgtct gcccggtcga ggcgatattc cacgacgacg acctgcccgg cgactggtcc
    28621 gcgttccgta ccgccgaccg cgaggtcttc gtccagctcg gctcccccgg cggcgccggt
    28681 gcccggtgcg cacccgtacc cgaccacccc ttcgtcgccg aactccccac ccgtacggcc
    28741 ctgtcggctt ccccgtccgc acgatcgcag gagtcatgaa caacgccatg aacgacgtct
    28801 tcacacgact cgcaggcgaa ggggtctccg tctggctcga cgacttccaa cgctccggaa
    28861 ccaccctgag cgagctgcgc cgagcggtcg gcccgcacgg cgtcacgggg gcggtcggcc
    28921 ggaccgacac gttcgccgag ctgttgcaca ccagtccccc gtaccggtca cggatacggg
    28981 agttggcgca tggcgacctc accgcggagg agctggtgtg ggccctgacc acgcaggacg
    29041 tccgcacggc gtgcgacgaa ctgcgtgccg cccatgagcg caccgcggga cgcgacggct
    29101 tcgcctccgt cgacgtcgac ccgaggaacg cctgggacgc gggcgcgacc gtggccgagg
    29161 cccgtgccct gtggcgcacg gtcaaccggc cgaacctgct ggtgaagatc cccgccacgg
    29221 ccccgaacct ggccgcgatc agcacctgcc tcgcggaggg catcggggtg aacgccgtcg
    29281 cgatcttctc ccccgaccgc tatgcgcagg tgtccgacgc cttcctggac ggcctggagc
    29341 gggcccgggc cgccgggcgc gacctgcggt ccatcgcctc ggtcgcctcg ttctccgtca
    29401 actgcctcga cgtcgaggtg gaccgggagc tggaccgggc cggcagcgcg gaggcgcggg
    29461 cgatgtcggg gaaggccggg atcgccaacg cccgtctggc gtacgagatc tacgaggact
    29521 cgctcgcctc gccgaggtgg cgcgctctcg cggcggccgg ggccgcacca cagcgcctcg
    29581 cctggacctc gaccgcccgc acgacaccgg cacgccccga cacctcgtac gtcgaggagc
    29641 tcgtggcccc cgacacggtg agcgtgctgt ccggggcgac gctgctcgcc gtcgccgatc
    29701 acggcgaggt caggggcgac agtgtgcgtc gccactacgc ggagtcgcgg cgcgtcctgt
    29761 cctacctgtc ctggttcggg atctcctacc ggacggtcgt gagctcgctc gaagcggtga
    29821 ccctccggca gtcggccgcc acctgggacg cgctgctgac ggccgtccgc ggcgaactcg
    29881 acgcacagcg ccggacgttg gccccgctgc ggtgaccacc gtcgtcccgc tcggggccgg
    29941 ggagcgaggt caatgcgtca actcggggcg gcatggggcg ccgatctgac aagctcgggc
    30001 gccacccgtg gtccggaccg gcccgtcggc ggaagctgcg tgcggcgttc ggcaccacga
    30061 gggaaggagt ccgcgcatgc gcggtcccgc cacgggaccg gccgagcgcg tacgtgacgg
    30121 actcacttca cgaaggaact ccatggctct ctcccccggc acgtcccgag cggccgcctt
    30181 cgaggcccgc gtcccgggtt cgaagtccct gaccaaccgg gcgctgttgc tggcggccgc
    30241 ggcccgttcg gccagcaccc tgcgtgcccc gctggtcagc gacgacacgg tcgctttcct
    30301 gaacgccctg gtggaactcg gcgtccgcgt cgaaaggacc ggcggcgacg acgtgtggtc
    30361 gctgaccggg ctcggtgcgg gcccggtcgg cccggcgcgg gtgtggtgcg ccgatgcggg
    30421 cacggcggca cgcttcctgc cgcccttcgc ggccgcaggc cacggcgacg tactcttcga
    30481 agccaccgac cagctcaccg cccggccggt ggcaccactc gccgaagcgc tgcggcagtt
    30541 gggcgccgac gtcaccaccg gcccggacgg caggctgccg ctgcgggtcc gctcccaggg
    30601 cctcgacggc ggcacgctga gtcttgacgg agccctcagc agtcagttcc tgaccggcct
    30661 gctgatggcg ggcccgctga tgcgcacacc gctcgtactg accgtgcaca acctcgtctc
    30721 ccggccctac gtcgcgatga cgacggcgtt gatgcggcac ttcggtgcgg acgtcgccgg
    30781 agaggacgac gtcttcaccg tcggcacggg tgggtaccgg ggcgccgacc tcctcatcga
    30841 accggacgcc tccacggcct cctacttctt cgccgcggcg gcggccaccg gcaccagcgt
    30901 gacggtcacc gggctcggca cggggagttc ccagggcgac ctccggttcg tcgaggtgct
    30961 caagctcacc ggcgcacacg tgcagagcac cccggaggcg accacggtca ccgggacggg
    31021 gcagctcagg ggcgggttca cggtcgacat gggtgatgtc tcggacacct tcatgacact
    31081 ggcggccctg gccccgctgg ccgacgcccc catcacgatc cggggcgtcg ggcacgcacg
    31141 gctcaaggag tccgaccgga tcgcggcggt cgagcggaac ctgggggccc tgggcatcca
    31201 tacccgtgcg ggccgggact ggatcaccgt gcaccccgga cgcccggcac cggcacggat
    31261 cgcctgccac cgggaccatc gcatcgccat ggcgttttcc gtgctcggcc tcaggagcga
    31321 gggcctcacg ctcgacgacc ccgactgcgt cggcaagacg ttccccgggt ttcacgagga
    31381 actgcaccgg atcttcccgc agcacaccgc ccggaggggg caccgttgag caggttgcgt
    31441 tggctgaccg cgggggagtc ccacggaccc gcacttgt
//
