LOCUS       NZ_BMUU01000009        22460 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence09, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000009
VERSION     NZ_BMUU01000009.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 358300)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 69908
            Orig. end                         :: 92368
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22460
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22460
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22460
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12460](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12460)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1121..1135)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.83"
                     /tool="antismash"
     gene            complement(1195..3474)
                     /db_xref="GeneID:96292949"
                     /locus_tag="IE233_RS24635"
                     /old_locus_tag="GCM10010326_50270"
     CDS             complement(1195..3474)
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96292949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019992437.1"
                     /locus_tag="IE233_RS24635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50270"
                     /product="DNA polymerase III subunit gamma and tau"
                     /protein_id="WP_190028324.1"
                     /transl_table=11
                     /translation="MSSLALYRRYRPESFAEVIGQEHVTDPLQQALRNNRVNHAYLFSG
                     PRGCGKTTSARILARCLNCEQGPTPTPCGECQSCRDLARNGPGSIDVIEIDAASHGGVD
                     DARELREKAFFGPASSRYKIYIIDEAHMVTSAGFNALLKVVEEPPEHLKFIFATTEPEK
                     VIGTIRSRTHHYPFRLVPPGTLRDYLGEVCGREGIPIEDGVLPLVVRAGAGSVRDSMSV
                     MDQLLAGAADDGVTYAMATALLGYTDTSLLDSVVDAFASGDGAAAFEVVERVIEGGNDP
                     RRFVADLLERLRDLVILAAVPDAGEKGLIDAPADVVERMQAQASVFGAAELSRAADLVN
                     AGLTEMRGATSPRLQLELICARVLLPAAYDDERSLQARLDRLERGVNFQTAPAGAPAMG
                     YVPGPEAHAPMQGGPGGPEGARAAVRGAGAEGPGPMGGPAPSQPAAPMPQAPAPQPAQS
                     QPAQAEPRPVQQAPAAQPQPAPPAEASPAGAWPSAAAPGQGGGQRPGAWPGASAAPSAG
                     AWPTAAPASAPAPAAPEPAPVAQAAAPAPGGQGNAMQVRNMWPDILEAVKNKRRFTWIL
                     LSQNAQVAGFDGTTVQLGFINAGARDNFASSGSEDVLRSVLSERFGVQWKVEAIIDPSG
                     GTQPPPAAGNFGGAATPRPPAPPVQQPQQSQQPQQNQQYQPPQAPSPAPRPASTAPAAP
                     APQSPRPPQASAPVRQEEPPPPPVRLEDDVPEDDDPDLVDNALSGHDLIVRELGATVVE
                     EYTNEG"
     misc_feature    complement(3585..3594)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.85"
                     /tool="antismash"
     ncRNA           complement(3593..3687)
                     /db_xref="RFAM:RF00169"
                     /db_xref="GeneID:96292950"
                     /gene="ffs"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="IE233_RS24640"
                     /ncRNA_class="SRP_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="signal recognition particle sRNA small type"
     gene            complement(3593..3687)
                     /db_xref="GeneID:96292950"
                     /gene="ffs"
                     /locus_tag="IE233_RS24640"
     tRNA            3760..3847
                     /anticodon=(pos:73702..73704,aa:Ser,seq:gga)
                     /db_xref="GeneID:96292951"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IE233_RS24645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10010326_t00620"
                     /product="tRNA-Ser"
     gene            3760..3847
                     /db_xref="GeneID:96292951"
                     /locus_tag="IE233_RS24645"
                     /old_locus_tag="GCM10010326_t00620"
     gene            complement(4150..4668)
                     /db_xref="GeneID:96292952"
                     /locus_tag="IE233_RS24650"
                     /old_locus_tag="GCM10010326_50280"
     CDS             complement(4150..4668)
                     /codon_start=1
                     /db_xref="GeneID:96292952"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002026.1"
                     /locus_tag="IE233_RS24650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50280"
                     /product="two-component system response regulator"
                     /protein_id="WP_190028325.1"
                     /transl_table=11
                     /translation="MPADMKVLLVDDHEDNLFAMESILAPLGYPLELATSGDAALKAAL
                     HGGIAVAVLDVVMPGVSGLDVARYLSRLTQTQLIPVILVTGMGQDSELASQALHLGVAD
                     YLIKPLDPWALRIKVQYLYRASTLLTAAPRQRGPRNHPAEPAQLPSRRRQLHPPETIRV
                     PRRPDEPPR"
     misc_feature    complement(4324..4326)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4799..4812)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     misc_feature    5112..5127
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.5"
                     /tool="antismash"
     gene            5227..6444
                     /db_xref="GeneID:96295828"
                     /locus_tag="IE233_RS39590"
                     /old_locus_tag="GCM10010326_50290"
     CDS             5227..6444
                     /codon_start=1
                     /db_xref="GeneID:96295828"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS39590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_50290"
                     /product="hypothetical protein"
                     /protein_id="WP_190028326.1"
                     /transl_table=11
                     /translation="MNALPAPARHRSPALSRTAIGIVLGLVAGWLLLVTVPHALDVERA
                     FTAAGDCPVAEVSTECRHTVAATVTSTAADHQHRSTYYWLGLGHAQDGPMALPGRLKAS
                     PHTRGPGRAVAAVPRRIKMDGRTPVFALVRPGAALQLTYWRGEIRYVEYRSLRQYTTAD
                     PRGGYRLPLAAALFLLSVGVACLRGAYCSARRATGVPGAAGPIEASGSAGSAGAGSQEP
                     WRITLPLASVLLISCFAFGTPWVTGGVPTAVLLTTVGAVPVLAGSAWVTHRRRRRTTDT
                     IKVAPLAPFVEECFPGTIRGEVPYSQEGFGYLVAAPGLLASTPDPFGRLARCPVPRTLT
                     VVRVRPPYWTDPGPRPAPGSQVVECRDGPTPVYVVTEHCYSAWVLGALRRPADSQFRAG
                     GTARRS"
     gene            complement(6593..7144)
                     /db_xref="GeneID:96292953"
                     /locus_tag="IE233_RS24660"
                     /old_locus_tag="GCM10010326_50310"
     CDS             complement(6593..7144)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96292953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010475079.1"
                     /locus_tag="IE233_RS24660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50310"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_229892886.1"
                     /transl_table=11
                     /translation="MSSGSVPPDPTSPSATEWRTRPEAPADIAAVRAVNLAAFPTASEA
                     DLVDALRADEAWIPGLSIVTVAPDGSVAGHALLTRCRVDGAPALALAPVAVTPEHQRTG
                     AGSAAVRAALRAARELGEDLVLVLGHPDYYPRFGFARASALGIRAPFEVPDEALMALRL
                     RPEGAPAPTGVIQYAAPFGV"
     gene            complement(7365..8912)
                     /db_xref="GeneID:96292954"
                     /locus_tag="IE233_RS24665"
                     /old_locus_tag="GCM10010326_50320"
     CDS             complement(7365..8912)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (106-341). E-value:
                     1.6e-18. Score: 59.2. Matches aSDomain:
                     nrpspksdomains_IE233_RS24665_Abhydrolase_1.1"
                     /codon_start=1
                     /db_xref="GeneID:96292954"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.5"
                     /locus_tag="IE233_RS24665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50320"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_190028327.1"
                     /sec_met_domain="PF00561 (E-value: 9.6e-29, bitscore: 95.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGESKLARRAIAAGAGAALALAGPATVTRADGPGPDLGRFYEQK
                     IGWEPCEPTEGQTGELLDSVRDMECSTLSVPVDYADPGKGAIALALARIRSAAPGDERK
                     GSVVFNFGGPGESGVDGLAAFRDLAAGIDKHYDLVSFDPRGVARSSPVRCGGEDEAGQL
                     DGEGQDAPGTGAAAVAEAQRVARACRAKTGPVLDHVGTINTSRDMDVLRAVLGDNKLNY
                     LGISYGTRLGAVYASQFPKRTGRMVLDAVDTLRGTAEQDALAQTRGFQQALEAFFAGCA
                     QQNCELGTSPQQVVATFDRAVAKLAGGKTVTGSDNQDFTGDDLHSAVQSALYSQASWPT
                     LSAGIAALLDDDDPTVLATLNPGAGTDDAPASNSDEAMLAINCADDPVRPADPAKAYDS
                     VQRQLTAESPYFGPGSAARAVACAGWPAGTDYIRRIDRPGAPKILVVGGKGDPATPYPW
                     ARDTARQLGSGVLLTYEGEGHGAYAASQCVRAKADAFFATGTVPPEGTSCPAEEPDE"
     aSDomain        complement(7890..8594)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS24665_Abhydrolase_1.1"
                     /evalue="1.60E-18"
                     /label="IE233_RS24665_Abhydrolase_1.1"
                     /locus_tag="IE233_RS24665"
                     /protein_end="341"
                     /protein_start="106"
                     /score="59.2"
                     /tool="antismash"
                     /translation="VVFNFGGPGESGVDGLAAFRDLAAGIDKHYDLVSFDPRGVARSSP
                     VRCGGEDEAGQLDGEGQDAPGTGAAAVAEAQRVARACRAKTGPVLDHVGTINTSRDMDV
                     LRAVLGDNKLNYLGISYGTRLGAVYASQFPKRTGRMVLDAVDTLRGTAEQDALAQTRGF
                     QQALEAFFAGCAQQNCELGTSPQQVVATFDRAVAKLAGGKTVTGSDNQDFTGDDLHSAV
                     QSALYSQASWPTL"
     gene            complement(9018..9941)
                     /db_xref="GeneID:96292955"
                     /locus_tag="IE233_RS24670"
                     /old_locus_tag="GCM10010326_50330"
     CDS             complement(9018..9941)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96292955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520221.1"
                     /locus_tag="IE233_RS24670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50330"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_161252643.1"
                     /transl_table=11
                     /translation="MGHDHGAPSAASGTLSGTYRNRLLWTIGISASITLIQVVGALLSG
                     SLALLADAAHSLTDAVGVSLALGAITLAQRAPTPRRTFGFYRVEIFSAVLNALLLAAIF
                     VWVLYSAIRRFSEPVEVKGGLMFAVAVGGLAANLVGLWLLKDAKDKSLNLRGAYLEVLG
                     DALGSVAVIVGGLIILFTGWQAADPIASIVIGLLIVPRTYGLLRDALHVLMEAAPNDVD
                     LAEVRRHLLEEPGVVDVHDLHGWTVTSGMPVLTAHVVVKETALDGGYGELLTRLQSCVG
                     DHFDVAHSTIQLEPEGHTEAADSLHR"
     gene            complement(10001..12460)
                     /db_xref="GeneID:96292956"
                     /locus_tag="IE233_RS24675"
                     /old_locus_tag="GCM10010326_50340"
     CDS             complement(10001..12460)
                     /EC_number="4.2.3.-"
                     /codon_start=1
                     /db_xref="GeneID:96292956"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981792.1"
                     /locus_tag="IE233_RS24675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50340"
                     /product="terpene synthase family protein"
                     /protein_id="WP_229892887.1"
                     /sec_met_domain="T1TS (E-value: 4.2e-84, bitscore: 277.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQPFVLPDSYLPYPARLNPHLDSAREHSRTWARDMGMLEGSGIW
                     DLADLDAHDYALLCSYTHPDCDAEQLALVTDWYVWVFFFDDHFLEMFKRTLDRKGGKEY
                     LDRLPAFMPMDLADGFPEATNPVEAGLADLWARTVPSMTKEWRERFAISTRNLLNESLW
                     ELANINAGRIANPVEYIEMRRKVGGAPWSAGLIEYAANAELPASVAGSRPLRVLTDAFS
                     DAVHLRNDLFSYQREVEDEGELSNGVLVLETFLGCTTQQAAEAVNDLLTSRLQQFENTA
                     LTEVPALCLEKGLTPDQRAAVAAYVKGLQDWQSGGHEWHMRSSRYMNEGAALGPSWSDG
                     VLGTSALDVSALFGRPAEARHRSFTHVPRQKVGPSLLPDFDVPYPLTISPHVDHARVES
                     MAWADRMGLLDDIWDAEKLAGYDFALCSAGLDPDATPDELALSAEWLTWGTYGDDYYPL
                     VYGRPRNLAGARAATERFFACMPVDVPAAGALAAVTPMERGLADLWARTAGPMSVEART
                     AFRRSVDVMLESWLWELHNQGQHRIPDPVDYIEMRRYTFGSDLTMSLSRLRHAGQLPPG
                     LYESGPIRSLENAAADYCCLLNDVFSYQKEIEYEGEVHNGVLVVQNFFDCDYPTALRIV
                     DDLMRSRLRQFQHVIDNELPLLVEDFELDQNGRETLGAYVAELQDWIAGILNWHASVRR
                     YGAADLPGSLPHGSSPHTASRGGVAPGWMRPSGDGTSADRVRLPEAWKAAVTATMPPAS
                     TPSVTSGPSATSVSPATPVPSATPVPPVPSLPAGLPVPTVAVPSLPVSAEWSPTLPAPT
                     VAGGHAS"
     gene            12812..13393
                     /db_xref="GeneID:96292957"
                     /locus_tag="IE233_RS24680"
                     /old_locus_tag="GCM10010326_50350"
     CDS             12812..13393
                     /codon_start=1
                     /db_xref="GeneID:96292957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018836499.1"
                     /locus_tag="IE233_RS24680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50350"
                     /product="HhH-GPD-type base excision DNA repair protein"
                     /protein_id="WP_190028329.1"
                     /transl_table=11
                     /translation="MNTTLRLAQQPEADALLGRSPLAALVGMLLDQQVPMEWAFSGPYT
                     IARRMGADDLDAEAIAAYDPEAFAELLKEKPAVHRYPGSMAKRIQQLCGFLVEEYGGDA
                     AGVWTGVASGAELFSRLKALPGFGEQKARIFLALLGKQLGVRPRGWREAAGPYGEAGSF
                     RSVADITGPESLAKVRAYKQEAKAAARAAK"
     gene            complement(13440..15143)
                     /db_xref="GeneID:96292958"
                     /locus_tag="IE233_RS24685"
                     /old_locus_tag="GCM10010326_50360"
     CDS             complement(13440..15143)
                     /codon_start=1
                     /db_xref="GeneID:96292958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240526.1"
                     /locus_tag="IE233_RS24685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50360"
                     /product="helicase HerA-like domain-containing protein"
                     /protein_id="WP_190028330.1"
                     /transl_table=11
                     /translation="MTDSDQTAAAREPISAAEPDETGARNPAPAPADAPAPPVPADAAP
                     AEPAGTAPAVPQPAAEIAAGYGFTGPAMELGALLWDGQCLPDAPIRIPLSMLNRHGLVA
                     GATGTGKTKTLQLIAEQLSANGVPVFLADVKGDVSGISAPGQSGDKVAERAGQVGQEWE
                     AAGFPCEFYGLGGIGPGIPLRATVTSFGPVLLSKVLQLNQTQEQSLGLIFHYADTKGLE
                     LYDLKDLKAVVGFLVSDVGKAELKGIGGLSSVTAGVILRAITAFEQQGAEAFFGEPEFD
                     TSELLRLAPDGRGLVSVLELPAVQDKPHLFSTFLMWLLADLFQKLPEVGDVDRPKLVFF
                     FDEAHLLFNGASKAFLESITQTVRLIRSKGVGIFFVTQTPKDVPADVLAQLGNRVQHAL
                     RAFTPDDAKALKATVRTFPHSPYDLEEVLTSLGTGEAVITVLSENGAPTPVAATRLRAP
                     QSLMAPIDPGALDQAVKSSILYARYAEPVDRESAFEKLSAAERAREEAAVSAALDPSAG
                     SGKPAGRGKKQDASLAEQVVSSGIFRSLARSVGTQLGREISRSIFGTRRR"
     gene            15240..15536
                     /db_xref="GeneID:96292959"
                     /locus_tag="IE233_RS24690"
                     /old_locus_tag="GCM10010326_50370"
     CDS             15240..15536
                     /codon_start=1
                     /db_xref="GeneID:96292959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949502.1"
                     /locus_tag="IE233_RS24690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50370"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_053725882.1"
                     /transl_table=11
                     /translation="MIFKRIGSGRPYPDHGRESTRQWADVAPRPVRLDQLVTTKGQLDL
                     ETLLAEDSTFYGDLFAHVVKWQGDLYLEDGLHRAVRAALQQRQVLHARVLEMD"
     misc_feature    15604..15620
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.24"
                     /tool="antismash"
     gene            15650..16279
                     /db_xref="GeneID:96292960"
                     /locus_tag="IE233_RS24695"
                     /old_locus_tag="GCM10010326_50380"
     CDS             15650..16279
                     /codon_start=1
                     /db_xref="GeneID:96292960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240524.1"
                     /locus_tag="IE233_RS24695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50380"
                     /product="LytR C-terminal domain-containing protein"
                     /protein_id="WP_161244421.1"
                     /transl_table=11
                     /translation="MSMLTPPGMGGKYRIKGDAYPRMRRPRKRGRLVLALVGAVVALGL
                     IGWGTVQLIDVFGGGGGKAKAAAHAKNCPAPAASGSGAPQALPKPAQITVNVYNATPRG
                     GLAKSVADELKKRGFAIGKVGNAPTEYDKKVANNGVLLGAPTAARGPFSVLGTQLAGTT
                     QKTDTRDTPDVDLILGNTFANLNTPKDADTALAALAKPAPAPSGKC"
     gene            complement(16297..16932)
                     /db_xref="GeneID:96292961"
                     /gene="upp"
                     /locus_tag="IE233_RS24700"
                     /old_locus_tag="GCM10010326_50390"
     CDS             complement(16297..16932)
                     /EC_number="2.4.2.9"
                     /GO_function="GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96292961"
                     /gene="upp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006141414.1"
                     /locus_tag="IE233_RS24700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50390"
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="WP_100575818.1"
                     /transl_table=11
                     /translation="MRIHVVDHPLVAHKLTTLRDKRTDSPTFRRLADELVTLLAYEATR
                     DVRTEQVDIETPVTPTTGVKLSYPRPLVVPILRAGLGMLDGMVRLLPTAEVGFLGMIRN
                     EETLEASTYATRMPEDLSGRQVYVLDPMLATGGTLVAAIRELIKRGADDVTAVVLLAAP
                     EGVEVMERELAGTPVTVVTASVDERLNEHGYIVPGLGDAGDRMYGTVD"
     gene            17056..17235
                     /db_xref="GeneID:96292962"
                     /locus_tag="IE233_RS24705"
                     /old_locus_tag="GCM10010326_50400"
     CDS             17056..17235
                     /codon_start=1
                     /db_xref="GeneID:96292962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019887716.1"
                     /locus_tag="IE233_RS24705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50400"
                     /product="hypothetical protein"
                     /protein_id="WP_161244420.1"
                     /transl_table=11
                     /translation="MPDERDRAQQPESDADRRRRRAQFLRELHEAKALRDRVQPRRARA
                     ARMRQAMRMRTFRW"
     gene            17464..18012
                     /db_xref="GeneID:96292963"
                     /locus_tag="IE233_RS24710"
                     /old_locus_tag="GCM10010326_50410"
     CDS             17464..18012
                     /codon_start=1
                     /db_xref="GeneID:96292963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740985.1"
                     /locus_tag="IE233_RS24710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50410"
                     /product="hypothetical protein"
                     /protein_id="WP_161244422.1"
                     /transl_table=11
                     /translation="MYFAALLARTEDGWEASDTELDDVETLSDLADLAREAAADGADDT
                     VLVFIEQEDAWFGVVRVDGEEDPRVFVSNAAVAARSSYGAMLTDELLGHDQDDEEDELD
                     TLDLDGTEDGYEDEAATAVDGPDGDEPSDGAVPAGPLGESAILADLGVSEGRLLALDGD
                     ALVTIADALGAAEVLEAVR"
     gene            18057..18485
                     /db_xref="GeneID:96292964"
                     /gene="tadA"
                     /locus_tag="IE233_RS24715"
                     /old_locus_tag="GCM10010326_50420"
     CDS             18057..18485
                     /EC_number="3.5.4.33"
                     /GO_function="GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96292964"
                     /gene="tadA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019887718.1"
                     /locus_tag="IE233_RS24715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50420"
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="WP_161244419.1"
                     /transl_table=11
                     /translation="MRSALAGAAQAESAGDVPVGAVVLAPDGTFLASGHNEREATGDPT
                     AHAEVLAIRRAARETGEWRLTGCTLVVTLEPCVMCAGAIVQSRIDRVVYGARDEKAGAA
                     GSLWDLVRDQRLNHRPEVVAGVLEEECSAQLTAFFRQR"
     misc_feature    complement(18522..18542)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.93"
                     /tool="antismash"
     tRNA            18544..18631
                     /anticodon=(pos:88486..88488,aa:Ser,seq:cga)
                     /db_xref="GeneID:96292965"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="IE233_RS24720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GCM10010326_t00630"
                     /product="tRNA-Ser"
     gene            18544..18631
                     /db_xref="GeneID:96292965"
                     /locus_tag="IE233_RS24720"
                     /old_locus_tag="GCM10010326_t00630"
     misc_feature    19043..19058
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            19057..19797
                     /db_xref="GeneID:96292966"
                     /locus_tag="IE233_RS24725"
                     /old_locus_tag="GCM10010326_50440"
     CDS             19057..19797
                     /codon_start=1
                     /db_xref="GeneID:96292966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073854.1"
                     /locus_tag="IE233_RS24725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50440"
                     /product="ANTAR domain-containing protein"
                     /protein_id="WP_161244418.1"
                     /transl_table=11
                     /translation="MISDGMADVLRSLRHGDGGVLAAACARALQVDGVAVSLLLGAGRD
                     AEPEPLWRSPGIAADFEELQFTLGTGPAPDAAHSGTAVVAPDLAAVRADRWPGLPAEAL
                     KLGVAGAYCFPLGLGAIRLGVLTAVTGRADDTVPEQRYADALALAAALTGLLLEHDGGG
                     DGQAVSGTVTGAPRELHRAVVHQATGMVSVQLDVSLADALLRLRAFAYARDLPLGDVAE
                     DVVARRLRFNDDMDGPPELGGRKG"
     misc_feature    complement(19073..19087)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            19794..20543
                     /db_xref="GeneID:96292967"
                     /locus_tag="IE233_RS24730"
                     /old_locus_tag="GCM10010326_50450"
     CDS             19794..20543
                     /codon_start=1
                     /db_xref="GeneID:96292967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063131.1"
                     /locus_tag="IE233_RS24730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50450"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_190028331.1"
                     /transl_table=11
                     /translation="MIDMIREQRLAEIFMEVADSLTDDFDVLDLLQRLSTRCVELLDVS
                     AAGILLADAVGELQIVAASDEHTRLLELFALQHDQGPCVECYRSGNARTNIDLNSHGAT
                     ASWPRFAARARETGYVATHAIPLRLRDRNIGALNLFQKTPHLLGESDIALAKALAGVAT
                     ITILQQRTLEQSHIERTQLQTALNSRILVEQVKGILCERWSTSPDEAFSVFRGYARSHH
                     LRLADFAAAIIDGTFDTATIPQPLPRS"
     gene            21425..21586
                     /db_xref="GeneID:96292968"
                     /locus_tag="IE233_RS24735"
                     /old_locus_tag="GCM10010326_50460"
     CDS             21425..21586
                     /codon_start=1
                     /db_xref="GeneID:96292968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019992457.1"
                     /locus_tag="IE233_RS24735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50460"
                     /product="hypothetical protein"
                     /protein_id="WP_167158291.1"
                     /transl_table=11
                     /translation="MDIKKVLLYIAVVFVLYTIITSPVQAAGMVQTGFEGISSAAKGVG
                     EFMTNLIR"
     misc_feature    complement(21471..21485)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.38"
                     /tool="antismash"
     gene            21686..21979
                     /db_xref="GeneID:96292969"
                     /locus_tag="IE233_RS24740"
                     /old_locus_tag="GCM10010326_50470"
     CDS             21686..21979
                     /codon_start=1
                     /db_xref="GeneID:96292969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056642.1"
                     /locus_tag="IE233_RS24740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_50470"
                     /product="Dabb family protein"
                     /protein_id="WP_161245381.1"
                     /transl_table=11
                     /translation="MIRHLVLFKLNEGVQRDDERVVAGVKAFQELDGLVPEIEFWECAW
                     NITDRPIAYDFAINSAVADADALKRYIEHPAHQAAAGQWREFATWVIADYPF"
     misc_feature    22141..22157
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.34"
                     /tool="antismash"
     misc_feature    22345..22359
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
ORIGIN
        1 gcggtgaccg agaggacccg gccacccgcg ctgacgaccg cgtcgccgtc gagcctggtc
       61 ccggcgtgca ggacgtacgc cgtcggcccg tcctcgtccg cgacctcggc cagaccgtcg
      121 atcgggtccc cggtgcgggg cgtcgcgggg tagttgtgcg aggcgatgac cacggtgacg
      181 gcggcgtcgt cgcgccaggc cagcggggcc tgtacgtcca gggtgccgtt ggccgcgtgg
      241 aacaggacgc ccgcgagcgg ggtctggagg cgggcgagga cgacctgggt ctcggggtcg
      301 ccgaagcgcg cgttgaactc gatgacccgc acgcctcgcg aggtgatcgc gaggcccgcg
      361 tacagcagtc cggagaacgg cgtaccgcgg cggcgcagtt cgtcgacggt cggctggagc
      421 acgctctcca tgacctcgtc gacgagcttc gggtcggccc acggaagcgg cgaataggcg
      481 cccatgccac cggtgttggg gccctcgtcg ccgtcgagcg cgcgcttgaa gtcctgcgcg
      541 ggctggagcg gcaggacggt gacgccgtcg gtgatcgcga agagggagac ctcggggccg
      601 tcgaggaact cctcgatgac gacgcgctca caggcgagcg cgtgctcacg ggccgcggcg
      661 aggtcgtcgg tgacgacgac gcccttgccg gccgcgagac cgtcgtcctt caccacgtac
      721 ggagccccga aggcgtccag cgcctcgtcg atctcctcgg gggtggtgca cacgtaggag
      781 cgggcggtgg gcacgctcgc cgccgccatc acgtccttgg cgaaggcctt ggagccctcc
      841 agctgcgcgg cctccttcga ggggccgaag caggggatgc ccgcatcccg cacggcgtcg
      901 gcgacgccgg cgacgagggg ggcctcgggc ccgaccacga ccagctcgct gcccagctcg
      961 acggcgaggc gggcgaccgc gtccccgtcc gtctggtcca cggggtggag ctcggcgacc
     1021 tccgcgatcc cggcgttgcc gggggcgcag tgcagcgccg tcacgtcggg gtcgagggac
     1081 agggaacggc acagggcgtg ctcgcgggca ccgccgccga tgacaaggac cttcacgccg
     1141 gccagcctag ccgccgggag ggcgtgatct ttgtgcgggt caccaggcgg acgctcagcc
     1201 ctcgttcgta tattcctcca ccacggtcgc cccgagctcg cgcacgatca ggtcatggcc
     1261 ggacagcgcg ttgtccacca ggtccggatc gtcgtcctcc gggacgtcgt cctccagccg
     1321 caccggcggc ggcgggggct cctcctggcg tacgggagca ctggcctgcg gcggccgcgg
     1381 cgactggggt gcgggcgcgg cgggggccgt cgatgcgggc cggggtgccg gtgagggcgc
     1441 ctgcggcggc tggtactgct ggttctgctg cggctgctgg ctctgctgag gctgctggac
     1501 gggcggggcg gggggccggg gggtggcggc gccgccgaag ttgcccgcgg cgggcggggg
     1561 ctgggtgccg cccgacgggt cgatgatcgc ctcgaccttc cactgcaccc cgaaccgctc
     1621 ggagagcaca ctgcgcagca cgtcctcgct gccgctgctc gcgaagttgt cccgggcccc
     1681 ggcgttgatg aagccgagct gcacggtggt gccgtcgaag ccggccacct gcgcgttctg
     1741 actgagcaga atccaggtga agcgccgctt gttcttgacg gcctccagaa tgtccggcca
     1801 catgttgcgc acctgcatgg cgttgccctg gccaccgggg gccggggcgg cggcctgcgc
     1861 gaccggagcg ggctccggtg cggccggtgc gggggcggac gcgggggcgg ccgtgggcca
     1921 ggcacccgcg gagggggcgg cggaggctcc gggccaggca cccgggcgct ggccaccgcc
     1981 ctgcccgggc gcggcggccg agggccaggc cccggcgggg ctcgcctcgg cgggcggggc
     2041 gggctgcggc tgagcggcgg gcgcctgctg tacgggccgg ggctcggcct gggcgggctg
     2101 cgactgagcg ggctgcgggg cgggcgcctg cggcatcggg gcggcgggct gcgacggggc
     2161 gggcccgccc atcggccccg gcccctcggc ccccgcaccc cgcaccgcgg cccgggcccc
     2221 ctcgggccca ccgggaccgc cctgcatcgg cgcatgcgcc tcgggcccgg gcacgtaccc
     2281 catggcgggc gcaccggcgg gcgccgtctg gaagttgacc ccgcgctcca gacggtcgag
     2341 gcgggcctgc agcgagcgct cgtcgtcgta cgcggcgggc agcagcaccc gggcacagat
     2401 cagttcgagc tggagccggg gcgaggtggc cccgcgcatc tcggtgagcc cggcgttgac
     2461 gaggtcggcg gcccggctca gctcggccgc gccgaacacg gaggcctgcg cctgcatccg
     2521 ctcgacgaca tcggccgggg cgtcgatgag ccccttctcg cccgcgtccg gaacggccgc
     2581 gaggatcacc aggtcccgca gccgctcaag caggtcggcg acgaagcggc gcgggtcgtt
     2641 gccgccctcg atgacccgct cgacgacctc gaaggcggcg gcgccgtcgc ccgacgcgaa
     2701 ggcgtcgacc acggagtcga gcagtgaggt gtcggtgtag ccgagcaggg cggtggccat
     2761 ggcgtacgtc acaccgtcgt cggcggcgcc ggcgagcagc tggtccatga cggacatcga
     2821 gtcacgcacg gatccggcgc cggcgcgcac gacgagcggc agcaccccgt cctcgatggg
     2881 aatgccctcg cgcccgcaga cctcgccgag gtagtcccgc agggtgccgg gcggcacgag
     2941 ccggaacgga tagtggtgcg tacgcgagcg gatcgtcccg atgaccttct cgggctcggt
     3001 ggtggcgaag atgaacttga ggtgctccgg cggctcctcg acgaccttca gcagggcgtt
     3061 gaagccggcc gaggtcacca tgtgggcctc gtcgatgatg tagatcttgt agcggctgga
     3121 ggcggggccg aagaaggcct tctcgcgcag ctcacgggca tcgtcgacac caccgtgcga
     3181 agccgcgtcg atctcgatca cgtcgatgga acccggcccg ttgcgcgcga ggtcccggca
     3241 ggactggcac tccccgcacg gggtgggcgt cggcccctgc tcacagttca ggcagcgggc
     3301 caggatgcga gcactggtcg tcttgccaca gccccgcggc ccgctgaaca ggtacgcgtg
     3361 attgacccgg ttgttccgca gcgcctgctg cagcgggtca gtgacatgct cctgcccgat
     3421 gacctcggcg aacgactcgg ggcggtagcg gcggtacagc gcaagggacg acacgcatac
     3481 gaggttatcg gggcccactg acaaccgggc ccgccgacgg cggcccgtcc cgggcccccc
     3541 ggccgaaccg gccccgcccg caaggggaac gggcatcccg cgccgcacaa aataaggcgc
     3601 cccccacgca cccgccagag ccgacctacc cttgctgcct tccggccctg ggggagttca
     3661 gtcagatagc gccacgtgag gggctccgca cagggtacct gatccctgag gtgggaacga
     3721 gttcgcgagc acccctcaac gtcttgtatt gtttgccgcg gaggattcgc ctagtggcct
     3781 agggcgcacg cttggaaagc gtgttggggg caacccctca cgagttcgaa tctcgtatcc
     3841 tccgccagtg cctcaccggg cacgatgttg aaggccccga ccgggaaacc ggccggggcc
     3901 ttctccgtgt ccggggcatc cccatggtcg ggtcttctcc gggcccgggg catccccacg
     3961 gtcgggcctt ctccgtgtcc ggggcatccc cgtggtcggg tcttctccgg gcccgggtgc
     4021 tcaccccgaa tcccggcctc cctatttccc ggcctcctcc gtgttccggc tctccctact
     4081 tcccgctcct tccgtgtacc gcccgaccgg cacaggaagg ccccgtccgg gaacccgggc
     4141 ggggccttct cagcgcgggg gctcgtccgg ccggcgcggg acgcggatgg tttccggggg
     4201 gtgcaactga cgtcgccgtg acgggagttg agccggttcc gcagggtggt tgcgggggcc
     4261 gcgctggcgt ggggcggccg tgaggagggt gctggcgcgg tagaggtact ggaccttgat
     4321 ccgtaaggcc caggggtcaa ggggcttgat caggtagtcg gccacgccca agtgcagtgc
     4381 ctgggaagcc agttcactgt cctggcccat cccggtcacc aggatgacgg ggatcagctg
     4441 ggtctgggtg aggcggctca ggtagcgggc gacgtccagg ccgctcacgc cgggcatcac
     4501 gacgtcgagg accgcgaccg ctatcccccc gtgcagcgcg gccttgaggg cggcgtcccc
     4561 gctggtcgcg agctccagcg ggtagccgag cggcgcgagg atgctctcca tggcgaacag
     4621 gttgtcctcg tggtcgtcga ccagtagcac cttcatgtcc gcgggcatgg ccccatcacc
     4681 ttcagtcggg agcgccgaat aggcatatgc ccgttcgcga cggctcgtac gcagtcgggg
     4741 agcaccactg tggtgtgcat gtggggaatg cacctcgatg cacctcggtg cacctgtggc
     4801 aacgcatgtg ccgggttggt ccgcacatag tcgacggctg gctcgtgtgg accgaattct
     4861 cgcaccgggc gccccggaac atcagggtgt cgacgatgtc tgttgccgcc gccccggacc
     4921 gcgtccacgc cccgccctcc gccgctcccc cgcggcacgc agtgcctacg cgcacatgcc
     4981 agtggcccat gttctgcccg gctcacacct atgggtgaac ccgcgcaggt cggcgggccg
     5041 atccgcgccg gggtgcgccg gcgcggcgac caccgcttga tcgattccgc cgggccccag
     5101 gccgacggcc caatggtctg aaccaccgtt ccacggagga aacttcgggt tcggatgggt
     5161 tcacgatgac cggatgatga tcccgccatc cccttccgcg gggcacgcgc ccccgagcgg
     5221 cgagcgatga acgcgctccc cgccccggcc cgccaccggt cgcccgccct cagtcgcacg
     5281 gcgatcggca tcgtgctcgg gctcgtcgcc ggctggctgc tcctggtcac cgtgccccac
     5341 gcactcgacg tcgagcgcgc gttcacggcg gcgggcgact gcccggtcgc cgaggtctcg
     5401 acggagtgca gacacaccgt cgcggccacg gtgacctcga ccgcggccga ccaccagcac
     5461 cgctccacgt actactggct gggcctcggc cacgcacagg acgggcccat ggcgctgccc
     5521 gggcggctga aggccagccc gcacacgcgc gggccgggcc gggccgtcgc cgcggtcccg
     5581 cgccgcatca agatggacgg ccgcaccccc gtcttcgctc tggtccggcc cggcgccgcg
     5641 cttcaactca cgtactggcg tggggagatc agatacgtcg aataccggag cctgcgccag
     5701 tacacgacgg cggacccgcg cggcggttac cggctgccgc tggccgccgc gctcttcctg
     5761 ctctccgtgg gcgtggcctg tctgcgcggc gcgtactgct cggcacggcg tgccaccggg
     5821 gtccccgggg cggccgggcc catcgaggcc tccggatccg ccgggtccgc cggggcgggc
     5881 tctcaggagc cctggcggat caccctgccg ctcgcctcgg tgctgctgat ctcgtgtttc
     5941 gccttcggta cgccgtgggt caccggcggg gtgccgaccg ccgtgctgct gacgacggtc
     6001 ggggcggtac cggtcctcgc cgggtccgcc tgggtgacgc accgccgtcg gcgccgcacc
     6061 accgacacca tcaaggtggc cccgctggcc ccgttcgtcg aggagtgctt cccgggcacg
     6121 attcgcggtg aagtccctta cagccaggag gggttcggct atctggtcgc cgcaccgggc
     6181 ctgctcgcct ccactcccga cccgttcggc cggctcgccc gctgccccgt gccgcgcacc
     6241 ctcacggtgg tccgggtccg cccgccgtac tggaccgatc cagggccccg gcccgcaccc
     6301 ggatcacagg tggtggagtg ccgggacggg ccgaccccgg tctatgtggt gaccgaacac
     6361 tgttacagcg cctgggtgtt gggggccttg aggcgccctg cggactccca gttccgggcg
     6421 ggcggcacgg cacggcggtc gtagccgcgc ggccggggcg actcggcagt tgcgactcgg
     6481 cccggggcca ctcgacccgg ggcgactcgg ccgtcgtcgc acatccgtcg tcgcacgtcc
     6541 gtcgtcgcac gtccgccgca gcgccccgcc gccgcgcatg tgggggccgc gcctatacgc
     6601 cgaacggcgc cgcgtactgg atcacgcccg tcggcgccgg agctccctcg ggccgcagcc
     6661 ggagcgccat cagggcctcg tcgggcacct cgaagggggc ccggatgccc agcgccgagg
     6721 cccgggcgaa cccgaagcgc gggtagtagt ccgggtggcc gagcaccagg accaggtcct
     6781 cgcccagctc ccgcgcggcc cggagcgccg cccgcaccgc ggcggaaccc gcgcccgtgc
     6841 gctggtgctc cggagtcacc gccaccgggg cgagggccag cgccggggcg ccgtccaccc
     6901 ggcaccgggt gagcagggcg tggcccgcga ccgagccgtc cggggccacc gtcacgatcg
     6961 agagcccggg gatccacgcc tcgtcggcgc gcagcgcgtc gacgaggtcc gcctcggagg
     7021 cggtggggaa cgcggccagg ttcacggccc gtaccgccgc gatgtccgcc ggggcctcgg
     7081 gccgggtacg ccactccgtg gcgctgggcg aggtgggatc gggcggtacg gaccccgaag
     7141 acacgggggc ggacgacgtg ggcgcgggcg atacggaccc cgaggacgtg gggccggacg
     7201 acctgggccc gggcgatgtg ggcgccgaag acatggggtc ggacgacgtg ggctcggggg
     7261 ccatgtgcgg agtatccata tgtgaccgat cgtgccattc gccccgcccc cggcccagcg
     7321 aatttccggc ggccgcccgt gggcgggcgc gccggtccgg acggctactc gtccggctcc
     7381 tccgccggac agctggttcc ctccggcggc accgtcccgg tcgcgaagaa ggcgtccgcc
     7441 ttggcccgta cgcactgcga ggcggcgtac gcgccgtgcc cctcgccctc gtacgtcagc
     7501 agcacacccg acccgagctg tcgcgccgtg tcccgcgccc atgggtacgg cgtcgccggg
     7561 tcgcccttgc cgcccacgac caggatcttg ggcgcgccgg gacggtcgat gcggcggatg
     7621 tagtccgttc cggccggcca ccccgcgcag gcgaccgccc gcgcggccga accgggcccg
     7681 aagtacggtg attccgcggt gagttggcgc tgtaccgagt cgtacgcctt cgccgggtcg
     7741 gccggccgca ccgggtcgtc cgcgcagttg atcgcgagca tcgcctcgtc ggagttgctc
     7801 gcgggcgcgt cgtccgtgcc cgcgcccggg ttgagcgtgg cgaggaccgt cgggtcgtcg
     7861 tcgtcgagga gggcggcgat gccggccgac agggtgggcc aggaggcctg gctgtagagg
     7921 gcggactgca cggcgctgtg caggtcgtca ccggtgaagt cctggttgtc ggagccggtc
     7981 acggtcttcc cgccggccag cttcgcgacc gcacggtcga aggtcgcgac gacctgctgc
     8041 gggctggtgc cgagctcgca gttctgctgg gcgcagccgg cgaagaacgc ctccagggcc
     8101 tgctggaacc ccctggtctg ggcgagcgcg tcctgttcgg cggtgccgcg cagggtgtcg
     8161 accgcgtcca ggaccatccg gcccgtccgc ttcgggaact ggctcgcgta gaccgcaccg
     8221 agccgggtcc cgtacgagat ccccaggtag ttgagcttgt tgtcgccgag caccgcgcgc
     8281 aacacatcca tgtcgcggga ggtgttgatg gtgcccacgt ggtcgagcac cgggccggtc
     8341 ttggcgcggc aggcccgggc gacgcgctgc gcctcggcca cggcggcggc ccccgtaccc
     8401 ggcgcgtcct ggccctcgcc gtccagctgc cccgcctcgt cctcgccgcc gcagcgcacg
     8461 ggggagctgc gggcgacccc gcgcgggtcg aagctcacca ggtcgtagtg cttgtcgatg
     8521 ccggccgcca ggtcccggaa ggcggcgagg ccgtccaccc cggattcgcc ggggccgccg
     8581 aagttgaaca cgacggaccc cttgcgttcg tcgccggggg ccgcgctcct gatgcgggca
     8641 agggcgagcg cgatggcgcc cttgccgggg tccgcgtagt cgaccggcac actgagggtg
     8701 ctgcactcca tgtcccttac ggagtcgagg agttcaccgg tctggccctc ggtgggctcg
     8761 cacggctccc agccgatctt ctgctcgtag aaccgcccca ggtccggccc gggtccgtcg
     8821 gcgcgggtga cggtggcggg cccggccagg gccagggccg ctccggcacc ggccgctatc
     8881 gcccgccgag cgagcttcga ctcacccttc atggactcac ccttccagga agcgcagccc
     8941 cccgaacagg ctagacagcc ccgcccgaac ccgcgcgccg agcactgctc acgctcggtg
     9001 accgcggggc ggggcggtca gcggtgcagg gagtccgcgg cctcggtgtg gccctcgggt
     9061 tccagctgga tcgtggagtg ggccacgtcg aagtggtccc ccacacagct ctggagccgg
     9121 gtcagcagct ccccgtaccc tccgtccagg gcggtctcct tcaccaccac atgtgcggtg
     9181 agcacaggca tgccggacgt caccgtccaa ccgtgcaggt catgtacgtc gaccacaccc
     9241 ggctcttcga ggaggtggcg gcggacctcg gcgaggtcca cgtcgttcgg ggcggcttcc
     9301 atcagcacgt gcagggcgtc ccgcagcagc ccgtacgtcc gcggcacgat caggagaccg
     9361 atgacgatgg aggcgatcgg gtcggcggcc tgccagcccg tgaagaggat gatcaggccg
     9421 cccacgatca ccgccaccga gccgagcgcg tcgccgagca cttccagata ggcgccgcgc
     9481 agattgaggc tcttgtcctt cgcgtccttc agcagccaca ggcccaccag gttcgcggcg
     9541 agtccgccca ccgcgaccgc gaacatgagg ccgcccttga cctcgaccgg ctcgctgaag
     9601 cgccggatcg ccgaatacag cacccagacg aagatcgcgg cgaggagcag ggcgttcagg
     9661 accgccgaga agatctccac ccggtagaag ccgaaggtgc ggcgtggggt cggggcccgc
     9721 tgggcgagcg tgatcgcgcc gagtgcgagg gagacgccga ccgcgtcggt gaggctgtgc
     9781 gcggcgtcgg cgagcaacgc gaggctgccg gagagcagcg cgccgaccac ctggatcagg
     9841 gtgatcgacg cgctgatgcc gatggtccac agcagccggt tgcggtacgt gccgctgagc
     9901 gtgccggacg ccgccgaggg cgcgccgtgg tcgtgcccca tgcgcgcgcc tcctcgtggc
     9961 cgggtccggc cccgggatgt ggcccccgca catcagagga tcacgaggca tggcctcccg
    10021 ccaccgtggg cgcgggaagg gtgggcgacc actcggccga cacgggcagg gacggcacgg
    10081 ccaccgtggg caccgggagc cctgccggca gcgagggcac agggggcaca ggggtcgccg
    10141 agggcacagg ggtcgccggg gaaaccgagg tcgcggaggg accagaggtc acggaggggg
    10201 tcgacgccgg gggcatcgtg gcagtgaccg ccgccttcca ggcctccggc agccggaccc
    10261 ggtccgccga ggtcccgtcc ccgctgggcc gcatccaccc gggggccaca ccacctcggg
    10321 acgccgtatg gggtgagctg ccatggggca ggctccccgg aaggtcggcg gccccgtacc
    10381 ggcgtaccga ggcgtgccag ttcaaaatcc ccgcgatcca gtcctggagt tcggccacat
    10441 aggcgccgag cgtctcccgt ccgttctggt cgagctcgaa gtcctcgacc agcagcggga
    10501 gttcgttgtc gatgacgtgc tggaactggc gcagccgcga gcgcatcagg tcgtccacga
    10561 tgcgcagggc cgtggggtag tcgcagtcga agaagttctg gacgaccagg acgccgttgt
    10621 gcacctcgcc ctcgtactcg atctccttct ggtacgagaa gacgtcgttg agcaggcagc
    10681 agtagtcggc ggccgcgttc tccaggctgc ggatcgggcc gctctcgtag agtccgggcg
    10741 gcagttggcc cgcgtggcgc aggcgcgaca ggctcatggt gaggtcggag ccgaaggtgt
    10801 agcggcgcat ctcgatgtag tcgacggggt cggggatgcg gtgctggccc tggttgtgca
    10861 gctcccagag ccagctctcc agcatgacgt cgacggaccg gcggaaggcc gtgcgggcct
    10921 cgacggacat cggcccggcg gtgcgcgccc acaggtcggc gaggccgcgc tccatcgggg
    10981 tcaccgcggc cagggcgccc gcggcgggca cgtcgaccgg catgcacgcg aagaaccgct
    11041 cggtggccgc ccgcgccccg gccaggttgc gcggcctgcc gtacaccagc gggtagtagt
    11101 cgtcaccgta ggtcccccag gtcaaccact cggcgctgag ggcgagttcg tccggtgtcg
    11161 cgtccgggtc gagccccgcc gagcagaggg cgaagtcgta gcccgccagc ttctcggcgt
    11221 cccagatgtc gtcgagcagc cccatacggt ccgcccaggc catcgactcc acacgtgcgt
    11281 ggtccacatg cgggctgatc gtcagtgggt acggcacgtc gaagtcgggc agcaaggacg
    11341 ggccgacctt ctgccgcggc acatgggtga agctgcggtg ccgggcctcg gcggggcggc
    11401 cgaacagggc ggagacgtcg agcgccgagg tgccgagcac cccgtcggac caggaggggc
    11461 cgagggcggc gccctcgttc atgtagcggc tggagcgcat gtgccactcg tggccgccgg
    11521 actgccagtc ctggaggccc ttgacgtatg ccgcgaccgc cgcgcgctgg tcgggtgtga
    11581 ggcccttctc caggcacagc gccgggactt cggtgagcgc ggtgttctcg aactgctgga
    11641 gccgcgaggt cagcaggtcg ttgacggcct cggcggcctg ctgtgtcgtg cagccgagga
    11701 aggtctcaag taccagtacg ccgttgctga gttcgccctc gtcctcgacc tcgcgctggt
    11761 aggagaacag gtcgttgcgc agatggacgg cgtcggagaa ggcgtcggtg aggacccgca
    11821 gcggcctcga ccccgcgacg gacgcgggga gttcggcgtt cgcggcgtac tcgatgaggc
    11881 cggccgacca cggcgcgccg cccaccttgc ggcgcatctc gatgtactcg acggggttgg
    11941 cgatccggcc cgcgttgatg ttggcgagct cccacagcga ctcgttgagc aggttgcggg
    12001 tgctgatcgc gaagcgctcg cgccattcct tcgtcatcga cggaacggtg cgcgcccaca
    12061 ggtcggcgag gcccgcctcg accgggttgg tcgcctcggg gaacccgtcg gcgaggtcca
    12121 tgggcatgaa ggcgggcagc cggtcgaggt attccttgcc gcccttgcgg tccagggttc
    12181 gcttgaacat ctccaggaag tggtcgtcga agaagaagac ccacacgtac cagtccgtca
    12241 ccagggcgag ctgctcggcg tcgcagtcgg ggtgggtgta cgaacagagc agcgcgtagt
    12301 cgtgcgcgtc caggtccgcc aggtcccaga tcccggagcc ctccagcatg cccatgtccc
    12361 gtgcccaggt acgggagtgc tcccgcgcgg agtccaggtg gggattgagc cgggccggat
    12421 acggcagata ggaatccggc aggacaaaag gctggctcac tgcggtcgcc cctcttggta
    12481 cgcacatggc tggtacgcac gtacccggta cgcacgtgat ggtccggtcg gaactacccg
    12541 gcccggcctc ggccattcga gtgccgtacg tctgtcatac gaaagcgtga gtcgactcga
    12601 aaagggcgcg ggggcgcggc ttgtgtgggc tgcgcacagg ggcttgggca catgggggct
    12661 gcgcacatgg gggatgggca cgtgggggca cgtgagccgc gccccgtatc ggggcgggca
    12721 tgtcggggcg gggagtgtcc gtccgcgctc ccctggggac ccgggggggt gtccgcgtgc
    12781 gccggggtcg tcggccgtcg atcatcgagg catgaacaca acccttcggc tcgcccagca
    12841 gcccgaggcc gacgcgctgc tcgggcgcag cccgctggcc gcgctcgtcg gcatgctgct
    12901 cgaccagcag gtgcccatgg aatgggcgtt ctcgggcccg tacacgatcg cccggcggat
    12961 gggggccgac gacctcgacg cggaggcgat cgcggcgtac gacccggagg ccttcgcgga
    13021 gctcctcaag gagaaaccgg cggtgcaccg ctaccccggg tcgatggcga agcggatcca
    13081 gcagttgtgc gggttcctcg tggaggagta cgggggtgac gcggccgggg tgtggacggg
    13141 agtggcgtcc ggggccgagc tgttctcgcg gctgaaggcg ctgccggggt tcggcgagca
    13201 gaaggcgagg atcttcctcg cgctcctggg gaagcagctc ggggtgcggc cccgggggtg
    13261 gcgggaggcg gcgggtccct acggggaggc cgggtccttc cgttcggtcg cggacatcac
    13321 cgggccggag tcgttggcga aggtacgggc gtacaagcag gaggcgaagg cggcggcgcg
    13381 ggccgcgaag tagccccgcc ggcccccggc ggccccgggt gcaaaccccc ggggccctgc
    13441 tacctgcggc gcgtgccgaa gatcgagcgg gagatctcgc ggcccagctg cgtccccacg
    13501 gatcgggcca gcgagcggaa gatgccgctg ctcaccacct gctccgccag cgaggcgtcc
    13561 tgcttcttcc cgcggcccgc cggcttgccc gagcccgcgg acgggtcgag cgccgccgac
    13621 accgccgctt cctcccgcgc ccgctccgcc gccgacagct tctcgaaggc ggattcgcgg
    13681 tcgaccggct cggcgtaacg ggcgtacagg atcgaggact tgacggcctg gtcgagggcg
    13741 ccggggtcga tgggcgccat cagggactgc ggggcgcgca gccgggtcgc cgcgaccggg
    13801 gtgggggcgc cgttctcgct cagcacggtg atgacggcct cgccggtgcc gagcgaggtc
    13861 aggacctctt cgaggtcgta gggggagtgc gggaacgtcc gtaccgtcgc cttcaacgcc
    13921 ttcgcgtcgt ccggcgtgaa ggcccgcagc gcgtgctgga cgcggttgcc gagctgggcc
    13981 aggacgtcgg cggggacgtc cttcggggtc tgggtcacga agaagatgcc cacacccttg
    14041 gagcggatca gccggaccgt ctgcgtgatc gactccagga acgccttgga cgcgccgttg
    14101 aacaggaggt gcgcctcgtc gaagaagaag acgagcttgg gccggtccac gtccccgacc
    14161 tcggggagtt tctggaagag gtcggcgagc agccacatca ggaaggtcga gaagaggtgg
    14221 ggcttgtcct ggacggcggg cagttcgagc accgacacca ggccgcggcc gtccggtgcg
    14281 agccggagca gctcgctcgt gtcgaactcc ggctccccga agaacgcctc ggcaccctgc
    14341 tgctcgaacg cggtgatcgc ccgcaggatc accccggcgg tgacggacga caggccgccg
    14401 attcccttga gttcggcctt gccgacgtcc gagaccagga agccgacgac cgccttcagg
    14461 tccttcaggt cgtagagctc caggcccttc gtgtccgcgt aatggaagat caggccgagc
    14521 gactgctcct gggtctggtt gagctggagc accttcgaca ggagtacggg tccgaagctg
    14581 gtgaccgtgg cgcgcagcgg gatgccgggg ccgatgccgc cgagaccgta gaactcgcag
    14641 gggaatccgg ccgcctccca ctcctggccg acctgcccgg cccgttcggc caccttgtcg
    14701 cccgactggc ccggggccga gatgccggag acgtcgccct tgacgtccgc gaggaacacc
    14761 ggcacgccgt tggcggagag ctgctcggcg atgagctgga gggtcttggt cttgccggtg
    14821 ccggtggccc cggcgaccag gccgtgccgg ttgagcatgg agagggggat gcggatgggc
    14881 gcgtccggca ggcactggcc gtcccacagc agcgcgccca gttccatcgc ggggcccgtg
    14941 aagccgtatc cggcggcgat ctcggcggcc ggctgcggca cggcgggggc ggtcccggca
    15001 ggttcggcgg gggcggcatc ggcgggcacg gggggcgcgg gcgcgtcggc gggcgcgggg
    15061 gcgggattcc gcgctccggt ttcgtccggc tccgcggcac tgatgggctc gcgcgcggcc
    15121 gccgtctggt cgctgtcggt catgacgagc cccctgcgtc gggtttttgg cgttttgccc
    15181 aggattgcac tcgggctcca tggctgcgcc cggagccgct cgcccggtag gctttccgtg
    15241 tgatcttcaa gcgcatcgga agcgggcggc cctaccccga ccacggccgg gaaagcaccc
    15301 ggcagtgggc ggatgtcgcg ccgcgcccgg tccggctcga tcagctcgtg accaccaagg
    15361 gccagctcga cctcgagacc ctcctcgccg aggactccac gttctacggc gacctcttcg
    15421 cgcacgtcgt gaagtggcag ggcgacctct acctggagga cgggctccac cgtgcggtac
    15481 gcgccgcgct ccagcagcgc caggttctgc acgcgcgcgt actcgaaatg gactgaaccc
    15541 gacagccggg tgagcctttc ggaccttttg cggcgcatac gggcgcacac gcgcgccagc
    15601 ggttgatcat ttagtaggca tcgtcccggg tcggcactac cctgcgccta tgagcatgct
    15661 cactcccccc ggcatgggcg gaaagtaccg catcaagggt gacgcctacc cgcggatgcg
    15721 acgtccccgc aagcgcggcc ggctggtcct cgcgctggtc ggcgcggtcg tggccctcgg
    15781 cctgatcggc tgggggacag tccagctcat cgacgtgttc ggcggcggtg gcggcaaggc
    15841 caaggccgcc gcacacgcca agaactgccc ggcgcccgcc gcgtccggct ccggtgcgcc
    15901 ccaggcgctg ccgaagcccg cgcagatcac cgtcaacgtc tacaacgcga ccccgcgcgg
    15961 cggcctcgcc aagtcggtcg ccgacgagct gaagaagcgc ggcttcgcga tcggcaaggt
    16021 cggcaacgcg cccaccgagt acgacaagaa ggtcgccaac aacggcgtgc tgctcggcgc
    16081 gccgacggcg gcccgcggcc ccttctccgt actcggcacc cagctcgcgg gcaccacgca
    16141 gaagaccgac acgcgcgaca cgccggacgt cgacctcatc ctggggaaca cgttcgcgaa
    16201 cctgaacacg ccgaaggacg cggacacggc cctggccgcc ctggccaagc ccgcacccgc
    16261 gccctccggg aagtgctgag aaaccttcgc gaagccctag tcgacggtgc cgtacatccg
    16321 gtcgcccgcg tcgcccaggc ccggcacgat gtagccgtgc tcgttgaggc gctcgtcgac
    16381 cgaggcggtc accacggtca ccggcgtgcc cgccagctcg cgctccatga cctcgacgcc
    16441 ctcgggggcg gcgagcagca ccacggccgt gacgtcgtcg gcgccgcgct tgatcagctc
    16501 gcggatcgcc gcgacgagcg tgccgccggt cgccagcatg gggtcgagga cgtacacctg
    16561 acggcccgag aggtcctcgg gcatccgcgt cgcgtaggtg gaggcctcca gggtctcctc
    16621 gttgcggatc atgccgagga agcccacctc ggcggtcggc agcaggcgca ccatgccgtc
    16681 gagcatgccg agaccggccc gcaggatcgg gaccaccagg ggacgcgggt acgagagctt
    16741 cacgcccgtc gtcggcgtca ccggggtctc gatgtccacc tgctcggtgc gcacgtcccg
    16801 ggtggcttcg taggcgagca gggtgaccag ctcgtcggcg agccgccgga aggtcgggga
    16861 gtcggtgcgc ttgtcgcgca gcgtggtgag cttgtgcgcc acgagagggt ggtcgacgac
    16921 atggatccgc atgacgtcca cagtaaccgg ggcgtagggg acccgcgtcc cacctgctgt
    16981 tggttcaggc tggcgtcaag cgcccgaacg gggggaaggt ggaagacacg aaccgacccg
    17041 gggcggtgtg agccaatgcc ggacgagcgc gaccgagcgc aacaaccgga gagcgatgcg
    17101 gaccggcggc gacggcgcgc ccagttcctg cgcgaactgc acgaggcgaa ggcgttgcgc
    17161 gaccgggtcc agccccggcg cgcccgcgcg gcccgtatgc gccaggccat gcgcatgcga
    17221 accttccgct ggtgacccgc gaacccggcg ccccgaagcc cgtgctcacg gccatcggga
    17281 gcctctgacg gggtggcccg gagcccgcga tcatgacgcg tcggaagccg tgatcggggc
    17341 gaccggaaaa acgcaaccgc ggaagaactc tcgcaaccgc ggtgttttct gccacgattc
    17401 cgaatgaagc cacagccggg gggaccccca accggcacgc ctatgaccag tgggagagtc
    17461 acggtgtact tcgccgcact gctcgcgcgc accgaagacg ggtgggaagc gagcgacaca
    17521 gagctcgacg atgtggagac gctgtccgat ctggccgacc tggcccgtga agcagccgcc
    17581 gacggggccg acgacacggt gctcgtcttc atcgagcagg aggacgcctg gttcggcgtc
    17641 gtccgcgtcg acggcgagga ggacccgcgc gtcttcgtct ccaacgccgc cgtcgcagcc
    17701 cgctcctcgt acggggccat gctcaccgac gaactgctcg gccacgacca ggacgacgag
    17761 gaggacgagc tggacaccct tgacctcgac ggcacggagg acggctacga ggacgaggcg
    17821 gcgacggccg tggacgggcc ggacggtgac gaaccgtcgg acggcgccgt gccggccggg
    17881 ccgctcggcg agagcgcgat cctcgccgac ctcggcgtga gcgagggccg actgctcgcg
    17941 ctcgacgggg acgccctcgt gacgatcgcg gacgcgctgg gcgcggccga ggtcctggag
    18001 gccgtccgct agtgccccac ccgcacgacc ccgtacgcga acggtgggcg gagccgatgc
    18061 gctccgccct tgccggggcc gcacaggccg aatcggccgg cgatgtgccg gtcggcgcgg
    18121 tcgtgctggc cccggacggc acgttcctgg cgtccgggca caacgaacgc gaggcgaccg
    18181 gcgatccgac cgcgcacgcg gaggtcctcg ccatccggcg cgcggcccgg gagaccggtg
    18241 agtggcggct gaccggctgc acgctcgtcg tcaccctgga gccgtgcgtg atgtgcgcgg
    18301 gcgcgatcgt ccagtcccgc atcgaccggg tcgtgtacgg ggcccgcgac gagaaggcgg
    18361 gcgccgccgg ttcgctgtgg gacctggtcc gcgaccagcg cctcaaccac cgccccgaag
    18421 tggtcgcggg cgtgctggaa gaggagtgtt cggcgcagct cacggcgttc ttccggcaac
    18481 ggtgacccag ctctcgccga accgatttca aaccacggcc caccttgggc taagctctct
    18541 ctcggtagcg tgtccgagcg gccgaaggag ctcgcctcga aagcgagtgt ggggaaactc
    18601 accgagggtt caaatccctc cgctaccgcc agcagtacga agggcccggt tcattgcgaa
    18661 ccgggctctt cgcgttgctc ggccccgtcg tcgccgatgt gacccggaac caccggattg
    18721 cgccaaaaga gcagggccgc cgggtacgcc gggcggccgg agcacccggc actccgacct
    18781 ccccgagccc cgaccacgcc cttgccggag ccctccgggg accatcaagg cccctacgcc
    18841 acacgcgact tgcccaccgc ccccttcgtg cccgcaccgg cgccctcccg cgaaacggtg
    18901 cccggagccg gtgggccggg cccggcaccg acgccgggcc ggcacggacg ggtatcggcc
    18961 ggaccgctcc ggccgacggc ggcgtcccac gggcgcggat aggcttccag gtgagagccg
    19021 ggggcagatc gccccgagcc cgacaggtgg agcccagtga tcagcgacgg catggccgac
    19081 gtgctccggt cgctccgtca tggtgacggc ggtgtcctgg ctgccgcctg cgcgcgtgcg
    19141 ctgcaggtcg acggtgtcgc cgtatcgctg ctcctcgggg cgggccggga cgcggagccg
    19201 gagccgctgt ggcggtcgcc cggcatcgcg gcggacttcg aggagctgca gttcacgctc
    19261 ggcacgggac ccgccccgga cgccgcgcac agtggcacgg ccgtcgtcgc accggacctg
    19321 gcggcggtac gcgccgaccg ctggcccggt ctgccggccg aggcactcaa actcggcgtg
    19381 gccggcgcgt actgcttccc cctgggactc ggcgcgatcc ggctcggggt gctcaccgcc
    19441 gtgacgggcc gggccgacga caccgtcccg gagcagcggt acgccgacgc cttggccctg
    19501 gccgcggcac tgaccggact gctcctggag cacgacgggg gcggggacgg tcaggccgtt
    19561 tccgggacgg tcacgggagc accccgggag ttgcaccggg cggtggtgca ccaggcgacc
    19621 ggcatggtca gcgttcagct ggacgtctcc ttggccgacg ccctgctgcg gctgcgggcg
    19681 ttcgcctacg cccgggacct gccgctcggc gacgtagccg aggacgtggt ggccagacgg
    19741 ctgcggttca acgacgatat ggacgggccg cccgagctcg gcggccgaaa gggatgatcg
    19801 acatgatccg cgaacaacgt ctggcggaga tcttcatgga ggtcgccgac tccctgacgg
    19861 acgacttcga cgtgctggac ctgctccagc gcctgtcgac ccggtgcgtc gagctcctcg
    19921 acgtgtccgc cgcgggcatc ctgctcgccg acgcggtcgg cgaactgcag atcgtggccg
    19981 cctcggacga gcacacccgg cttctggagc tgttcgccct ccagcacgac cagggcccat
    20041 gcgtggagtg ctaccgcagc ggcaacgccc ggacgaacat cgacctcaac agccatgggg
    20101 cgacggcgag ttggccccga ttcgcggcgc gggcccgtga gaccgggtac gtggccacgc
    20161 acgcgattcc gctacggctg cgcgaccgca acatcggtgc gctcaacctc ttccagaaga
    20221 ccccccacct cctgggcgag agcgacatcg ccctggccaa ggccctggcc ggcgtcgcca
    20281 cgatcaccat cctccagcag cgcaccctgg agcagtccca catcgagcgg acccagctcc
    20341 agaccgcgct caacagccgc atcctggtgg aacaggtcaa gggcatcctc tgtgagcgct
    20401 ggagcacctc accggacgag gcgttctccg tcttccgcgg ctacgcgcgc agccatcacc
    20461 tgcgactggc cgacttcgcc gccgcgatca tcgacggcac cttcgacacc gcgacgatcc
    20521 cccagcccct gccccggagc tgagcgacgg cggccgcctc cggcagccgg tcaccggctg
    20581 aaatcccacg cttgcgccgc cctcggcccg gcctaggatg cccagtgaac gcaagggcgg
    20641 acgccctcga accgtgcacg accggttcgg gcggctgccc ctcggccccc tgcccccggg
    20701 tctgcgctca ctgtccgccc cgctgacggg gcggccggag ccgctctcgg cagtgcgcgc
    20761 ggctccggcc cttcgtcctc gcggcgcgct tcgagccggg gccggtctcc cgcaggcctc
    20821 cgggcgccgc cgaggacggt tgacgcgagg agagtgcgga ggggagccca cctcctcgcg
    20881 cggacggccg ccgccacgcc cgaccgtgac cgggcggcgg ccgtcccaca aaagcagcat
    20941 cgtgatcgat gtccccgagt gccctttgaa cctactcccg ggcgctcccc gtggctcccc
    21001 cgcggccgac attggccgga ggcgacccct ccgcgccggg cccttccgcg ggcggtcacc
    21061 cgcggaggga ccgaagaagc cccggtcggg gaagtgaccg gggcttcgac gataggacgg
    21121 ggggagcggc atcgggggga caagccgctc cccccgatga gaacagaacc tgcaagccct
    21181 gcgccgcagt caggggggaa gctcgcggcg cggaccccgc agtgaggtcc tgttcctcac
    21241 ccaccgcatt cctgccagat gtggtgggct caggaaccat cctgctctcc cgtcacgtcc
    21301 gtaccgtcgg gcaaagggcc ccgatcgtca ggtcctaggt ccctaaaggc ctggtgagta
    21361 cgggacgggt ggcggttaga ctcacccgac cgcacagggg tggcgccggg gaggggctgg
    21421 cacagtggac atcaagaagg tcctgctcta catcgccgtg gtcttcgtgc tgtacacgat
    21481 catcacgtcg ccggtgcagg ccgcagggat ggtccagacc ggcttcgagg gcatatccag
    21541 cgcggccaag ggcgtcggcg agttcatgac caacctgatt cgctgagccc cccggccgcg
    21601 tcgccggtcg cgtccacgga cgcgtccgtg gacgagtcct cggccgcgcc cgggccggtt
    21661 cccgtcgtat tcgtaggaga gatgcatgat ccgccacctg gtcctgttca agctcaacga
    21721 gggcgtgcag cgcgacgacg agcgcgtcgt cgccggtgtg aaggccttcc aggagctcga
    21781 cgggctcgtt cccgagatcg agttctggga gtgcgcctgg aacatcaccg accggccgat
    21841 cgcgtacgac ttcgcgatca actccgccgt cgccgacgcg gacgcgctga agcggtacat
    21901 cgagcacccc gcgcaccagg cggcggccgg ccagtggcgc gagttcgcca cctgggtgat
    21961 cgccgactac ccgttctgac cccgcacgcg ttccgggctc ccgtccggtt cgcggcgccc
    22021 ggccccgcac ccgagaggtg cggggctttt tcgtcccccg gggcgcctcc gaacagggcc
    22081 atctgcccca acttgccctc aacacgtagt tatacggtgc ttgcacacag tggacatgtc
    22141 ttgtgatgct atgaccgctt ttgacggatg agttgaccga agactaaggg gtggcgtgac
    22201 cgtgccggcc agtactacgc ctcaagtgcc gccccagaac gagccccagg acgcccccga
    22261 agtgcccgcc caggactcgt cggagagccc caggggcccc gccagaacct ccaccagggg
    22321 cgcggacacc cgcgccctca cccaggtgct gttcggccag ctcaagcacc ttgagccggg
    22381 cacgccggag cacggccggg tgcgcggggc gctgatcgag gccaacctgc cgctggtgcg
    22441 ctacgcggcg gcccgcttcc
//
