LOCUS       NZ_BMUU01000006        22856 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence06, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000006
VERSION     NZ_BMUU01000006.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 557778)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 260882
            Orig. end                         :: 283738
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22856
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="4"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22856
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22856
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12856](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12856)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    486..498
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            652..1887
                     /db_xref="GeneID:96291915"
                     /locus_tag="IE233_RS19440"
                     /old_locus_tag="GCM10010326_39750"
     CDS             652..1887
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96291915"
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557883.1"
                     /locus_tag="IE233_RS19440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39750"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_190027827.1"
                     /transl_table=11
                     /translation="MTSFVTNPTGAAPQEQTYRVVLIEDDLADAVLVEELLLDTGLRFE
                     LTTCTSLAGARTDPALRTADCILLDLHLPDVSGTKAVAAVRAAAPHTAVIVLTGLSEAQ
                     AGSDAMAAGAQDYLVKGKVNADLLHRAVRYAVYRSQTELANAQTQAATLRAEENSRLER
                     GLLPQPLLSTSAVTVTTRYLPGTELALLGGDFLDVVEGDDGLLHAVVGDVSGHGPDAAA
                     LGVCLRIAWRSLILGGHRGRELLHLMERILIAERGDRPLFATCALLTLDHGAATAELHL
                     AGHHGPLLSTDRGSREITAAHGIALGIDPRVSNWPASLIPLPAAGALTLYTDGLTEGRN
                     GSARGRLGVEGLLTLIDRLPQSDPAAHIDLLIKETSALNAGRHSDDVAVLRLDWREPAA
                     PEPRTAPDRVRG"
     gene            1960..2397
                     /db_xref="GeneID:96291916"
                     /locus_tag="IE233_RS19445"
                     /old_locus_tag="GCM10010326_39760"
     CDS             1960..2397
                     /codon_start=1
                     /db_xref="GeneID:96291916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127320.1"
                     /locus_tag="IE233_RS19445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39760"
                     /product="ATP-binding protein"
                     /protein_id="WP_190027828.1"
                     /transl_table=11
                     /translation="MAKDSSLKAVGWARSLPLTSSVKEARDWTREHLATLDWARTSPDV
                     VDSVLLTVSELVTNAQVHARSTAQLILTWDEECLHVTVHDASPHLPEQRDPEADALGGR
                     GLLLIDLLADDWYAYPCPRGKSVTACFQPPTPARPEAVGGG"
     misc_feature    complement(1992..2006)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.2"
                     /tool="antismash"
     misc_feature    1993..2007
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.2"
                     /tool="antismash"
     misc_feature    2476..2489
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.57"
                     /tool="antismash"
     gene            2597..5233
                     /db_xref="GeneID:96291917"
                     /locus_tag="IE233_RS19450"
                     /old_locus_tag="GCM10010326_39770"
     CDS             2597..5233
                     /codon_start=1
                     /db_xref="GeneID:96291917"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS19450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_39770"
                     /product="hypothetical protein"
                     /protein_id="WP_190027829.1"
                     /transl_table=11
                     /translation="MQLDAVIAQLTFRERFSRKRVRFERDAGALVLQIEGGSDPVRQWL
                     ARLLKEYRGIVPVNNPSDVEESDPERQVLEQLQAVVEGCGYGGIVARGLPIVFPRFAAA
                     RAALYDRQQTGDHSHARRMGALKRQIEEAIAQERRHSMPQARTRLDPLIQDPYVTQQLG
                     GFLGLLLKIANALRLPCYRTVRWFRKRRFPGLRTFEAVCEELDGWSARPAHEKQRLLVE
                     ALLADVDAHYGVLRRLNRVRRPVILLPDVDTIPARRIIRDRMLEALSGTAKGLRVHPVV
                     ITTSRPGGTDPLTGGRPAVPADCLGEEIPGRFRERREVGASRAGGGSEPLPSLLVQIVL
                     DDAAGPRPAPGVRLLGPVTVGVTAVALIAAGLGGYVTFFREPAACGRGLEIHGGECVGV
                     SDGTGVFMPDVKGMPQVFERIAEQNKAVAGRKHATVALLIPMQSASPAVQRQILSEVQG
                     AYLAQVAANGADSVKPAIRLVLANPGDGYGRWRGTLDQLTAQEPDLRVVVGFNLSLDKT
                     KEALTYVTNTLHLPAVASVVTADDFANPEGTDTVPYPGLARVVSTSREQARALLAFDPG
                     LAGSETALVADDRPGDDYDRSLRDAFAEARRNEGGRGVQDMRFESPGVEEAGVTPNEFE
                     DFAGNICRSNTHVVYFAGRAFHLKLFVEKLATTYCREKASYTVITGSDATTLDERLDDH
                     DRALLRGDPGSGKPSVSIRYAAPAHPDSWSTELAKWQNDPRTKGQDPPLYLREAQDSMN
                     ALRRGIADQSGPIGPVNLDDGRTIVTYDVVLTASRALARAVHTSGLEVPTADRVVRDLG
                     KLNSDLRVRGAGGWICLTNAGNPYNKALSVVRLDPGSRQLVFEGVAWPTGHAPGHDDNC
                     VVPVHPE"
     misc_feature    complement(5370..5383)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.49"
                     /tool="antismash"
     gene            5375..5614
                     /db_xref="GeneID:96291918"
                     /locus_tag="IE233_RS19455"
                     /old_locus_tag="GCM10010326_39780"
     CDS             5375..5614
                     /codon_start=1
                     /db_xref="GeneID:96291918"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS19455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_39780"
                     /product="hypothetical protein"
                     /protein_id="WP_161254543.1"
                     /transl_table=11
                     /translation="MRMRTTLAAGALAIAAVLGSTGTALAHDRDDHHSGGETSACGSFA
                     GAGGGHAAWGSGCMHSQWEGMYPGRGFHHRLNGF"
     CDS_motif       5375..5401
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRMRTTLAA"
                     /locus_tag="IE233_RS19455_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5402..5614
                     /prepeptide="core"
                     /locus_tag="IE233_RS19455_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="6858.4"
                     /monoisotopic_mass="6854.1"
                     /core_sequence="GALAIAAVLGSTGTALAHDRDDHHSGGETSACGSFAGAGGGHA
                     AWGSGCMHSQWEGMYPGRGFHHRLNGF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRMRTTLAA"
                     /leader_location="[5374:5401](+)"
                     /alternative_weights="6876.4"
                     /alternative_weights="6894.4"
                     /alternative_weights="6912.4"
                     /alternative_weights="6930.4"
                     /alternative_weights="6948.5"
                     /alternative_weights="6966.5"
                     /alternative_weights="6984.5"
     gene            complement(5621..6202)
                     /db_xref="GeneID:96291919"
                     /locus_tag="IE233_RS19460"
                     /old_locus_tag="GCM10010326_39790"
     CDS             complement(5621..6202)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /db_xref="GeneID:96291919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957845.1"
                     /locus_tag="IE233_RS19460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39790"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_161254540.1"
                     /transl_table=11
                     /translation="MVHVRKMNGTDVEAVSAIRVRGWQSAYAGILPRSYLEAMTVEDDA
                     ARRREWFSLPHRRSVDLVAVDGGEPVGWINYGPSRSAVPDVRTGEINALYVRPGLTGRG
                     IGRGLLDEAHALMESQEFRAVLLWVLADNQGARRFYERAGYRADGHTQADVYDGVAVSE
                     LRYRRACWSGPRTGVADSTVGHTDASGSAR"
     CDS             complement(6202..6294)
                     /gene="allorf_267084_267176"
                     /locus_tag="allorf_267084_267176"
                     /protein_id="allorf_267084_267176"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAPRRSSFARHPLGASAASWCRRAPGRTVT"
     CDS_motif       complement(6250..6294)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAPRRSSFARHPLGA"
                     /locus_tag="allorf_267084_267176_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6202..6249)
                     /prepeptide="core"
                     /locus_tag="allorf_267084_267176_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="1546.7"
                     /monoisotopic_mass="1545.8"
                     /core_sequence="SAASWCRRAPGRTVT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAPRRSSFARHPLGA"
                     /leader_location="[6249:6294](-)"
                     /alternative_weights="1564.8"
                     /alternative_weights="1582.8"
                     /alternative_weights="1600.8"
     gene            complement(6401..8563)
                     /db_xref="GeneID:96291920"
                     /locus_tag="IE233_RS19465"
                     /old_locus_tag="GCM10010326_39800"
     CDS             complement(6401..8563)
                     /codon_start=1
                     /db_xref="GeneID:96291920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118352.1"
                     /locus_tag="IE233_RS19465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39800"
                     /product="TerD family protein"
                     /protein_id="WP_190027830.1"
                     /transl_table=11
                     /translation="MVHALEPLVVRHTHRLPAPCGAAGQGGVAARQFDAALMSVGFKLS
                     AELLGHLSALSEGTVVDTAVRTLDTVRAMVGDHVRHNAYFIDFPAHVPDTYAFWQQCVA
                     DAVDRGVAVAGLSDGVVDLLTLPAYGTYQHSYAELLAAHGELLAAAGDRLTVLHLGGAP
                     DDEITALYLALAGSAAPLGDGGLPDLEVLAGHCVHGPQPEAIPVRENRAVVNRARVEAG
                     ADPLLDTVTDVLRLACGLSDGDVTLVQPTRFRSPSRRVRRVLLAGLDAVVAANPAKLAD
                     VSAHREAFKRLGERLHAHEYAARWPHAADVFAVARGEKRARSFDSRVEELLAADDVLGA
                     ARLLESAPGKLFRCLDRLLRACATDAERDAVAGVAARLAPEVSGRVLLSVREHFHNRAR
                     GSGARRVFVNRLGRAWATDESRSPLPEAVRARLVAALDAETSRRLPVPGHLLIDPDVLD
                     VALPLSGRATAPGFGVLPRGSLSPVDGELLRFFVYWKQTSDTTDFDLSALMLNSAYETV
                     SWLSYTALTEVEGEHSGDITEAPDGASEFINLRLGAVRGTYIVPQVNIFSGEGFEEVEE
                     SFFGFMLREGDQRGRPFEPRTVRMKSQLRGPGRVALPLAFIRGEDGRWRAKWLHVYLKG
                     TPSANRVEGNRVSVAALVRGFVERDHLTVRHLTGLMADRGDVTTLWDGRTVPQGPVTYI
                     GLERPDGLHPDSCVITPENLGDLVPE"
     gene            8735..9967
                     /db_xref="GeneID:96291921"
                     /locus_tag="IE233_RS19470"
                     /old_locus_tag="GCM10010326_39810"
     CDS             8735..9967
                     /codon_start=1
                     /db_xref="GeneID:96291921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980420.1"
                     /locus_tag="IE233_RS19470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39810"
                     /product="aromatic acid exporter family protein"
                     /protein_id="WP_161245091.1"
                     /transl_table=11
                     /translation="MWEFTDPLFDFARRRREPAVVQTLRSTAAAVISYVVALHLSSEPA
                     PLTAPLTALLVVQVTLYTTLVTAVRRVNSVVVGVLLAVGFSSLVGLTWWSLGLIILAAL
                     VVGRFVKVGEFVPEVAISAMLVLGVTRVSATAWDRVLETLIGAGVGMLFNVLLAPPVWV
                     DSAGGAIEELAARMRRLLVDLGDEVGGHTPVAQAAARLHEARRLDHDIAQVDASLRQAE
                     DSLRLNPRVKEGLLSRVVLRTGLDTLEISAVVLRVVCRSLTDLAKERTEEHLFDPEVGL
                     ALRDVFEHLARAIESFAVLITTQVSTNAEEAEQRLTDELTAGRASRDRVADLLLAEVQR
                     HPRQWQLHGALLAEVDRILDELDVEKRSQRLVEELDRLSREQRRRWHLLRRVRSRTQQA
                     LRLPEPEDRRS"
     gene            complement(10001..12856)
                     /db_xref="GeneID:96291922"
                     /locus_tag="IE233_RS19475"
                     /old_locus_tag="GCM10010326_39820"
     CDS             complement(10001..12856)
                     /codon_start=1
                     /db_xref="GeneID:96291922"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240676.1"
                     /locus_tag="IE233_RS19475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39820"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_190027831.1"
                     /sec_met_domain="DUF4135 (E-value: 1.9e-72, bitscore:
                     239.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-39, bitscore:
                     131.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANAVVPGAPEETEHFARPVRSIARPWRDQLARALAELPSLDATE
                     RDVILEAGHTALLRSLHAKLSRLFLIELHALRLSGPAAGAGAAPGPGSASGSESGRAIW
                     DAFVEQAGAEGYLDGLSDRYPNLARRIATVARLSVTATAEFAERLAADRDLLAPLLGAP
                     AGRVRAVAFGAGDSHHGGLTVSRVDFAGGTVMYKPRPSEADVALGALLDDLFTGLPGAP
                     APDRRIRVPATLARDGYGWAEFIGHRYCADGAELAVFYRNLGHWLAVLRFTGGTDMHAE
                     NMIAAGPVPVIVDAETLFDAPAPFPPSGRGDAVDVAAAAIRRTVLRTGLLPVRGTGFAL
                     GGVDISGIGALPGQQPLIPHPVIADGGTATARFEVDLVAMPVAGNHPAATPVLSTYWDR
                     VLAGFREMTAHLRRPGLDPHRLLARFEGARARRILRPTQAYVDIGRMLWHPASLHDEAA
                     AVERARDILRRNADALPGAPTDRATIDGEIADLLVGDVPMFNFTVDAAAVRATVEDWRD
                     ADLAFEESVIQDALVGAYLNERSLPARVQEAAHAPHARDRERRRRELAARMVRRLSDGA
                     VRGEDGTVTWISPVFSPAGWSIRVLPADLYTGQGGVALTLAEYACEVRAGRADEVPGVR
                     ETFEGALRVLISTEDRTPTPSAGAFSGAASQVWTWLALHRVLGDDWMLERAAERALLLT
                     GGPLVDEDVEVDLLNGVAGAVVPLLDLATATGQTRWLDAAAHIGHRLGKLAVSDTGGAR
                     WPTRLNPEGIGGFAHGATGIGWALTRLALSEAGSAAERDDWNRLAARAFAFQESLYRPA
                     DGNWLDVRVGAEEDFFTSWCHGSAGIGIGMLDLHRRTGDPAHLDMARRAAGACAAEGFG
                     WSHTLCHGDLGLWEFLTSIGSGDARDLDAEILSGLEQRGPVGGLAREAFSPSLMSGLAG
                     VVHTLLRMHPDADLPNPLLLD"
     gene            complement(12990..13190)
                     /db_xref="GeneID:96291923"
                     /locus_tag="IE233_RS19480"
                     /old_locus_tag="GCM10010326_39830"
     CDS             complement(12990..13190)
                     /codon_start=1
                     /db_xref="GeneID:96291923"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240677.1"
                     /locus_tag="IE233_RS19480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39830"
                     /product="DUF6229 family protein"
                     /protein_id="WP_053728018.1"
                     /transl_table=11
                     /translation="MPQTSVPASAVLNAWLSGAESAYGQLNPAGPLYVGGAAAEAALTD
                     SSDSLYGFCSSPSGSHGSWCC"
     CDS_motif       complement(13119..13190)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPQTSVPASAVLNAWLSGAESAYG"
                     /locus_tag="IE233_RS19480_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12990..13118)
                     /prepeptide="core"
                     /locus_tag="IE233_RS19480_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="3973.3"
                     /monoisotopic_mass="3970.8"
                     /core_sequence="QLNPAGPLYVGGAAAEAALTDSSDSLYGFCSSPSGSHGSWCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPQTSVPASAVLNAWLSGAESAYG"
                     /leader_location="[13118:13190](-)"
                     /alternative_weights="3991.3"
                     /alternative_weights="4009.3"
                     /alternative_weights="4027.3"
                     /alternative_weights="4045.3"
                     /alternative_weights="4063.4"
                     /alternative_weights="4081.4"
     CDS             complement(13260..13487)
                     /gene="allorf_274142_274369"
                     /locus_tag="allorf_274142_274369"
                     /protein_id="allorf_274142_274369"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTWRIRALLGESPGINCSADVLVAGGQAGAGACRASIMPPPDSGA
                     FAGIGSAPPPARTTGVPRISAPVTLAGFRI"
     CDS_motif       complement(13410..13487)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTWRIRALLGESPGINCSADVLVAGG"
                     /locus_tag="allorf_274142_274369_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13260..13409)
                     /prepeptide="core"
                     /locus_tag="allorf_274142_274369_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.30"
                     /molecular_weight="4591.3"
                     /monoisotopic_mass="4588.5"
                     /core_sequence="QAGAGACRASIMPPPDSGAFAGIGSAPPPARTTGVPRISAPVT
                     LAGFRI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTWRIRALLGESPGINCSADVLVAGG"
                     /leader_location="[13409:13487](-)"
                     /alternative_weights="4609.3"
                     /alternative_weights="4627.3"
                     /alternative_weights="4645.3"
                     /alternative_weights="4663.3"
                     /alternative_weights="4681.4"
                     /alternative_weights="4699.4"
     gene            13519..14817
                     /db_xref="GeneID:96291924"
                     /locus_tag="IE233_RS19485"
                     /old_locus_tag="GCM10010326_39840"
     CDS             13519..14817
                     /codon_start=1
                     /db_xref="GeneID:96291924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060262.1"
                     /locus_tag="IE233_RS19485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39840"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_229892831.1"
                     /transl_table=11
                     /translation="MLWTAVGVVALAFLIGLEITARHYGERGPLSTQVREVLFAPKPGP
                     LYGGLALMMVVLTWRQRFVAAGVAIGVDAVFVLGRWACGVRVPEGHLFGNGALWAMLGC
                     AVFAITRRTGTERVLLLKGVGLGLLLVTGRKIGDSWLLITSKTCPTVLDPYVATADHAL
                     GNPSWLAGRALDAIGPAGSNLLGLIYAQLAVAAIVVALYQLRKVAAERRFPRHHLVRTF
                     LLIGLLGPAIYMIFPVVGPVFAYGPGASGTGGVEWSVANLWPHTPPPIAMPHPVPYDGI
                     TPRNCMPSLHTAWATAIFIHTRTGPRLLRYAGTFWLIATLAATLGFGYHYGVDLVAGVV
                     FSLTVEAALRTFDRGWDRSGLRLVAHGTAVFTLLLVSYRWLPVHMAARPWLFGPLVLLA
                     MGSVIHGYLRTTKRWTSPDAAPALLPEPQPEPV"
     gene            15102..15659
                     /db_xref="GeneID:96291925"
                     /locus_tag="IE233_RS19490"
                     /old_locus_tag="GCM10010326_39850"
     CDS             15102..15659
                     /codon_start=1
                     /db_xref="GeneID:96291925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374161.1"
                     /locus_tag="IE233_RS19490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39850"
                     /product="hypothetical protein"
                     /protein_id="WP_190027833.1"
                     /transl_table=11
                     /translation="MSLTVVIIVIAVVVVLIACAVAARLATVRRRRLQERFGPEYERTV
                     DEQDSRRAGEQELRERQERHDALDIKPLPAAARERYSQDWARVQEQFVDRPDDAVHDAD
                     RLVTTLMSERGYPTEGYEQQLKDLSVEHGETLQHYRAAHDINERSGRHQATTEELRGAM
                     VHYRALFEELLHNGDRPGRSTT"
     gene            15656..16222
                     /db_xref="GeneID:96291926"
                     /locus_tag="IE233_RS19495"
                     /old_locus_tag="GCM10010326_39860"
     CDS             15656..16222
                     /codon_start=1
                     /db_xref="GeneID:96291926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151052.1"
                     /locus_tag="IE233_RS19495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39860"
                     /product="hypothetical protein"
                     /protein_id="WP_190027834.1"
                     /transl_table=11
                     /translation="MSARPPRVGAERAHPSRTTTRDGRSEEMRYEETPRPDEGPLSTED
                     LAAGRQQDTGAEAPGPAGGAPTYPGEATAGREDRQEDAGDRAPGHARAEAEPAEDDEPL
                     LGSEQEEFRARWQQIQSRFVDDPQDSVNAADQLVAETMQALATTFSAHKRDLEGQWHRG
                     EEVPTEDLRVALQQYRSFFNRLLST"
     gene            complement(16238..16735)
                     /db_xref="GeneID:96291927"
                     /locus_tag="IE233_RS19500"
                     /old_locus_tag="GCM10010326_39870"
     CDS             complement(16238..16735)
                     /codon_start=1
                     /db_xref="GeneID:96291927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055547.1"
                     /locus_tag="IE233_RS19500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39870"
                     /product="hypothetical protein"
                     /protein_id="WP_190027835.1"
                     /transl_table=11
                     /translation="MNRFRSRYGASPLHLTAVLCSFALALYAGVRLLRGDTLGVVLWFV
                     GAALLHDLVLLPLYATADRALQRLLPATGRSGAHPVGDRVVGVNHVRVPAFVSGVLLLV
                     WWPLILGQVDGFTAATALPSDVFLGRWLLVTAALFAVSALCASARLWRRSSRERRRRDA
                     TG"
     gene            complement(16732..18012)
                     /db_xref="GeneID:96291928"
                     /locus_tag="IE233_RS19505"
                     /old_locus_tag="GCM10010326_39880"
     CDS             complement(16732..18012)
                     /codon_start=1
                     /db_xref="GeneID:96291928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049698.1"
                     /locus_tag="IE233_RS19505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39880"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_229892832.1"
                     /transl_table=11
                     /translation="MRAAVAAGPPPGPARPEFWRSPIRGPWLTAVFGLALLCGVSVLFV
                     TGLLSYAAYDPDLARINDQTPDKGVLGFYLFTWPTSPYWGYRLSQGVHVTLGIVLIPVL
                     LAKLWSVIPRLFEWPPVRSVGHALERLSLLLLVGGAGFEFATGVLNVQLHYVFPGSFYV
                     LHFYGAWVFIGAFVVHVVFRLRRAVIAVVKGPRAEEQHRARPLATAGPGLVAPRPAEPT
                     MSRRGAVLLVGAGSAALLVVTMGQSIGGWMRRTALLAPHGQDPGSGPNGFQINKTAASV
                     GVRPSDIGPSWRLTVRAGGRKTVLTRDELYALPRRTVELPIACVEGWSTPDQRWGGVRL
                     VDLAALVGVTHDAPRVLVESVQRGGSFGSVVLAANQVRDTRSLLAVEVNGAALSPDHGY
                     PARIVVPNAPGVHHTKWVTRLTFGEPT"
     gene            complement(18353..18985)
                     /db_xref="GeneID:96291929"
                     /locus_tag="IE233_RS19510"
                     /old_locus_tag="GCM10010326_39900"
     CDS             complement(18353..18985)
                     /codon_start=1
                     /db_xref="GeneID:96291929"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_39900"
                     /product="hypothetical protein"
                     /protein_id="WP_161245085.1"
                     /transl_table=11
                     /translation="MATASITGAVVTVNVEGATPLRLDMSLQRHSYRHCATSTVAGEIN
                     SLLYASVDDATVTAEAVEVGEQVETLLAKAKGSWKALFGKTLTVGSGRTYLVDNSGLNP
                     NGSPNHFFVTGGTGVWSKVSQADYVAARDVRRAEEAITARRGRGDTYDYLDSKKLNEKR
                     AEPGGATNPVVQAVQAARVSIAAASADDAALIAASGRKDLVTLIRSV"
     gene            complement(19159..19986)
                     /db_xref="GeneID:96291930"
                     /locus_tag="IE233_RS19515"
                     /old_locus_tag="GCM10010326_39910"
     CDS             complement(19159..19986)
                     /codon_start=1
                     /db_xref="GeneID:96291930"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960983.1"
                     /locus_tag="IE233_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39910"
                     /product="aldo/keto reductase"
                     /protein_id="WP_161245084.1"
                     /transl_table=11
                     /translation="MTAVPTITLNNGVRIPQLGFGTFQIPKDETRETTLAALEAGYRHI
                     DTAQMYGNEKEVGQAVRDSGLDRGDVFVTSKLNNDAHAHDDALAAFDRTMDELGLDHLD
                     LFLVHWPLPGKGDFTETWKAMEEIYGSGRAKAIGVSNFQPHHLRRLMESGVVVPAVNQI
                     EVHPYLTQDDVRAFGAEHGIATEAWSPIAQGKVLDDPAIKRIAERVGKSPAQVTLRWHI
                     QRGDIVFPKSVTQKRIEENFDLFGFELTEGDLGEISALNRDERTGPDPDRFNG"
     gene            complement(20072..21487)
                     /db_xref="GeneID:96291931"
                     /locus_tag="IE233_RS19520"
                     /old_locus_tag="GCM10010326_39920"
     CDS             complement(20072..21487)
                     /codon_start=1
                     /db_xref="GeneID:96291931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950856.1"
                     /locus_tag="IE233_RS19520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39920"
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_190027837.1"
                     /sec_met_domain="Aldedh (E-value: 1.4e-137, bitscore:
                     454.0, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQHKSSFATVNPATGETVAEFDAIEGEEADARLEAANRAFDAW
                     RRRPIEERAAVVGRAGALMRERKEELAQLITLEMGKLIAEARGEVDLAASILEYYAENG
                     PHFAAAEPLDVDEGEAYLLNEPLGVLLGVMPWNFPLYQVVRFAGPNLVLGNTVLVKHAG
                     ICPQSALALESLFFDAEAPEGVYTNLFVGHEEISRIIDSPVVRGASLTGSEKAGAQVAE
                     RAGRNMKPSLLELGGSDVFIVLDGERLERTVGAAAAGRMANTGQSCVASKRFIVLADVY
                     DDFVAGLRRAFEELRPGDPADESTTLGPLSSERAAADLVDQIRETVEQGAELVTGGRRI
                     DRPGAFVEPTILAGVKPGMRAYGEELFGPAAVIYRVADEEEAIALANDSQYGLGGTVFC
                     ADVERGRKVAERVETGMVWVNHPTSTQPDLPFGGIKRSGYGRELSKLGMQEFVNRKLVR
                     VLPPDAELRGIAG"
     gene            complement(21727..21963)
                     /db_xref="GeneID:96291932"
                     /locus_tag="IE233_RS19525"
                     /old_locus_tag="GCM10010326_39930"
     CDS             complement(21727..21963)
                     /codon_start=1
                     /db_xref="GeneID:96291932"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262001.1"
                     /locus_tag="IE233_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39930"
                     /product="chaplin"
                     /protein_id="WP_373300199.1"
                     /transl_table=11
                     /translation="MRMRTAIAAAALAVAGVLAGGASAVADAGAQGVAAHSPGVASGNL
                     VQIPVHIPINICGNTISVAGALNPAAGTTCINS"
     CDS_motif       complement(21901..21963)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRMRTAIAAAALAVAGVLAGG"
                     /locus_tag="IE233_RS19525_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21727..21900)
                     /prepeptide="core"
                     /locus_tag="IE233_RS19525_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.80"
                     /molecular_weight="5175.8"
                     /monoisotopic_mass="5172.7"
                     /core_sequence="ASAVADAGAQGVAAHSPGVASGNLVQIPVHIPINICGNTISVA
                     GALNPAAGTTCINS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRMRTAIAAAALAVAGVLAGG"
                     /leader_location="[21900:21963](-)"
                     /alternative_weights="5193.8"
                     /alternative_weights="5211.8"
                     /alternative_weights="5229.8"
                     /alternative_weights="5247.9"
                     /alternative_weights="5265.9"
                     /alternative_weights="5283.9"
     misc_feature    21955..21968
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.49"
                     /tool="antismash"
     gene            22142..22774
                     /db_xref="GeneID:96291933"
                     /locus_tag="IE233_RS19530"
                     /old_locus_tag="GCM10010326_39940"
     CDS             22142..22774
                     /codon_start=1
                     /db_xref="GeneID:96291933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980841.1"
                     /locus_tag="IE233_RS19530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_39940"
                     /product="DNA polymerase ligase N-terminal
                     domain-containing protein"
                     /protein_id="WP_190027838.1"
                     /transl_table=11
                     /translation="MARKHEARDGLSEYARKRDFSKTPEPEGEAARGKGREPVFVVQIH
                     DASTVHFDFRLEVDGVLKSWAVPKGPSGDPHDKRLAMPTEDHPMAYADFEGVIGEGYGA
                     GTVIVWDSGTYRSLATDRHHHEVPFAEALEHGHVSFWMEGTKLRGGYALTRIRRPRDGD
                     REAWLLVKEDDGHASAHSTTEPTRARSALSGRTLKQVADEAAEQTSP"
ORIGIN
        1 cctccagcgc cgctacggcg gacagctcga cgaacgggcc gaccagtaca tcgatttcgc
       61 ggtcgacggc gcgaaccgca tgcagaccct gatcaacgat ctgctcgagt tctcccgggt
      121 gggccgggtc cacaacaacc atcaggcggt ggacctgggc agggctctcg atcgcaccct
      181 gtcctcgctg agtctcagca tcgaggagac cggggcggag atcacgtacg acccgctgcc
      241 gaccctgatc gccgattcca cccagatggg catgctgtgg cagaacctga tcggcaacgc
      301 ggtcaagttc cgccgggccg gtcagacacc gcgcatccac gtgtcggccg tgcgcgatga
      361 cgtcctgtgg cggttcaccg tcaccgacaa cggcatcggc atcgcacccg agtacgccga
      421 caaggtcttc gtcatcttcc agcggctgca caccaaggac gcctacagcg gcagtggcat
      481 cgggctcgcg atgtgcaaga agatcgtcga gttccacggc gggacgatcg ccgtcgacct
      541 cacgcacgag cacggcaccc gcatcgtgtt caccctcgcc cccgagccgg cggaacgccc
      601 cgggccgggt gaactcgtcg gcgccgacgc ctcgcaggtg gtgccggcgt catgacctcc
      661 ttcgtgacca acccgaccgg cgcggcaccg caggagcaga cctaccgcgt cgtcctcatc
      721 gaggacgacc tggcggacgc cgtcctggtg gaggaactgc tcctggacac cgggctgcgg
      781 ttcgagctca ccacgtgcac gagcctcgcc ggcgcccgca ccgatccggc cctgcgcacg
      841 gccgactgca tcctgctcga cctgcacctg cccgacgtct ccggcacgaa ggcggtcgcg
      901 gcggtccggg cggccgcgcc acacaccgcc gtcatcgtcc tgaccgggct gtccgaggcc
      961 caggcgggca gcgacgcgat ggccgccggc gcacaggact acctggtcaa gggcaaggta
     1021 aacgcggatc tgctgcaccg ggcggtccgt tacgccgtct accggagcca gaccgaactc
     1081 gcgaacgccc agacccaggc ggccaccctg cgagccgagg agaactcccg gctggagcga
     1141 gggctgctgc cgcaaccgct cctgtccacg tcggccgtga cagtgaccac gcgctatctg
     1201 ccgggcaccg aactcgcgct gctcggcggc gacttcctgg acgtcgtgga aggggacgac
     1261 gggctgctgc acgccgtcgt cggcgacgtc agcgggcacg gacccgacgc cgccgcgctc
     1321 ggcgtgtgcc tgcggatcgc ctggcgctca ctgatcctcg gcggccaccg cggcagggag
     1381 ctcctgcacc tgatggagcg catcctgatc gccgaacgcg gcgaccggcc gctcttcgcg
     1441 acctgtgccc tcctcaccct cgaccacggc gcggccaccg ccgagctgca cctggccggc
     1501 catcacgggc ccctgctctc cacggaccgg ggatcacgcg agatcaccgc cgcgcacggc
     1561 atcgccctcg gcatcgaccc ccgggtgagc aactggcccg cgagcctcat cccgctcccg
     1621 gccgccggag cgctgaccct gtacaccgac ggcctgaccg aggggcgcaa cggctcggcc
     1681 cggggccgcc tcggagtcga gggcctgctc accctcatcg accggctgcc gcagtcggac
     1741 cccgccgccc acatcgacct cctcatcaag gagacctcgg cgctgaacgc gggacgccac
     1801 tccgacgacg tcgccgtgct ccggctcgac tggcgagagc ccgcggcccc ggagccccgg
     1861 accgcgccgg accgcgtccg gggctgacca cactgcggtt ttcggggcag acgggacgag
     1921 aagccggccg tcgagccgcc gtcgaaccaa ggagagaccg tggcgaagga ctcatcactg
     1981 aaggccgtgg gctgggcgcg ctcccttccg ctgaccagca gcgtgaagga ggcgagggac
     2041 tggacgcgcg agcatctggc gacgctcgac tgggcgcgga cgtcgcccga cgtcgtcgac
     2101 tcggtgctgc tcaccgtgtc cgagctggtc acgaacgccc aagtccacgc ccgcagcacg
     2161 gcgcagctca tcctcacctg ggacgaggag tgcctgcacg tcaccgtgca cgacgcctca
     2221 ccccacctgc ccgaacagcg cgaccccgag gccgatgccc tgggagggcg cggcctgctc
     2281 ctgatcgacc tcctcgccga cgactggtac gcctatccct gcccccgggg caagagcgtc
     2341 accgcctgct tccagccgcc cacgcccgcc cgtcccgagg cggtcggcgg cggttaggcc
     2401 gaagggagtg tgtgcgatgc gcaccacctg tccagatccg accgttcttg aacacatgga
     2461 tggtgaatga gcaactcgcc ccagatcaag ggcagttgac acctagagtg ctcaccgatt
     2521 cgacgtcggc cgagaacggc tacggccgcc gccgggcgcg cggcctacgc cagggccacg
     2581 gcaacgggga gcaagggtgc aactggacgc ggtcatcgcg caactcacgt tcagggagag
     2641 gttctcccgc aagcgggtgc gcttcgagcg ggacgccggg gcgctggtgt tgcagatcga
     2701 gggcgggagc gaccccgtac ggcagtggct cgcccggctg ctcaaggagt atcgcggcat
     2761 cgttccggtg aacaatccga gcgacgtcga ggagagcgac cccgagcggc aggtcctcga
     2821 gcagttgcag gcggtcgtcg agggctgcgg ctacggcggc atcgtggctc gcggcctgcc
     2881 gatcgtcttc ccgcgcttcg cggccgcccg cgccgcgctg tacgaccggc agcagaccgg
     2941 cgaccattcc cacgcccggc ggatgggagc cctgaagcgg cagatcgagg aagcgatcgc
     3001 gcaggagcga cggcactcca tgccgcaggc ccgcacccgg ctcgacccgc tgatccagga
     3061 tccgtacgtc acccagcaac tcgggggatt cctcggcctg ttgctgaaga tcgccaatgc
     3121 cctgaggctg ccgtgctacc gcacggtgcg ctggttccgc aagcggaggt tcccgggcct
     3181 gcgcacgttc gaagcggtct gcgaggaact ggacggctgg agcgccaggc ccgcacacga
     3241 gaagcagcgg ctgctcgtcg aggcgctgct cgccgacgtg gacgcgcact acggcgtgct
     3301 ccgccgcctc aaccgggtcc gccgtcccgt catcctcctg ccggacgtgg acacgatccc
     3361 cgcacggcgg atcattcggg acaggatgct cgaagcgctc agcggcacgg ccaagggcct
     3421 gcgggtgcac cccgtggtca tcaccacgtc gcgaccgggc gggacggacc cgctgacggg
     3481 cggccggccc gccgtgccgg cggactgcct cggcgaggag atcccggggc gcttccgtga
     3541 gcgccgggag gtgggcgcat cgcgggcggg cggcgggagc gaaccgctgc ccagcctgct
     3601 cgtccaaatc gtgctggacg atgccgccgg cccgcgtccc gcaccgggcg tgcgcctcct
     3661 gggcccggtg accgtgggag tcacggcagt cgcgctcatc gccgcggggc tcggcggcta
     3721 tgtcaccttc ttccgcgaac cggccgcctg cggaagggga cttgagatcc atggaggcga
     3781 gtgcgtgggc gtctccgacg ggaccggcgt gttcatgccc gacgtcaagg gcatgcccca
     3841 ggtcttcgag cgcatcgccg agcagaacaa ggcggtcgcg ggccgcaagc acgcgaccgt
     3901 cgccctgctg atcccgatgc agtccgccag tcccgccgtg cagcggcaga tcctcagcga
     3961 ggtgcagggc gcgtacctcg cgcaggtggc ggcgaacggc gcggactcgg tgaagcccgc
     4021 gatccggctg gtcctcgcca acccgggcga cgggtacggg cgctggcgcg gcacgctcga
     4081 tcaactcacc gctcaggagc cggacttgag ggtcgtggtg ggcttcaatc tgagcctgga
     4141 caagaccaag gaggccctca cgtacgtgac caacaccctg catctgcccg cggtggccag
     4201 cgtcgtgacg gcggacgact tcgccaaccc cgagggcacc gacacggtcc cctaccccgg
     4261 cctcgcccga gtcgtgtcca cctcccgcga gcaggcccgg gcgctgctgg cgttcgaccc
     4321 cggactggcg ggctccgaga ccgcgttggt ggcggacgac cggccgggcg acgactacga
     4381 ccgctccctt cgcgacgcgt tcgccgaggc caggcggaac gaaggcggac gcggggtcca
     4441 ggacatgcgc ttcgagtcgc ccggcgtcga ggaagcgggt gtcaccccga acgagttcga
     4501 ggacttcgcg ggaaacatct gccgctccaa cacccacgtc gtctacttcg ccggacgggc
     4561 cttccacctg aagctcttcg tggagaagct cgccaccacg tactgccgcg agaaggcgtc
     4621 gtacaccgtg atcaccgggt ccgacgccac cacgctcgac gagcgcctgg acgaccacga
     4681 ccgggccctg ctgcggggcg acccgggctc gggcaagccg tccgtcagca tccgctacgc
     4741 cgcaccggcg caccccgact cctggagcac cgagctcgcc aagtggcaga acgacccgag
     4801 gacgaagggg caggaccccc cgctgtacct gcgggaggcg caggactcga tgaacgcgct
     4861 gcgccgtggc atcgcggacc agtcggggcc catcggcccg gtgaacctcg acgacgggcg
     4921 gacgatcgtc acgtacgacg tcgtcctcac ggcgagccgg gcactggcgc gcgcggtgca
     4981 caccagcggt ctcgaggtac cgacggccga ccgtgtggtc agggatctcg ggaagctgaa
     5041 ctccgacctg cgcgtgcggg gcgccggcgg ctggatctgc ctcacgaacg cgggaaaccc
     5101 gtacaacaag gcgctgtcgg tggtgcgcct cgatcccggc tcgcgccagc tggtgttcga
     5161 gggcgtggcc tggccgaccg ggcacgcgcc gggtcacgac gacaactgcg tggtaccggt
     5221 ccaccccgaa tagcgcccgc ggcgaccatg cgatacggcc ggtgcaggcc cgtggcccgt
     5281 cgtggcggcg gtcgggtgac acaggtttcg cgacctgagg gcaccgggga ctgatcaccc
     5341 tgtttcccca cccgaacacc cgacaggagc agacatgcgt atgcgcacca ccctcgccgc
     5401 cggcgctctc gccatcgccg cggtcctcgg cagcaccggc accgccctgg cccacgaccg
     5461 ggacgaccac cactccggcg gcgagaccag cgcctgtggc tcgttcgccg gcgcgggcgg
     5521 tgggcacgct gcctggggtt ccggctgtat gcactcccag tgggagggca tgtaccccgg
     5581 ccgtggcttc caccaccgcc tcaacgggtt ctagccgctg ctagcgggca ctgccgctcg
     5641 cgtcggtgtg gccgacagtg ctgtcggcca caccggtccg cggcccgctc cagcacgcgc
     5701 gccggtatcg gagttcggac acggcgacac cgtcgtacac gtcggcctgg gtgtgcccgt
     5761 cggcccggta cccggcccgc tcgtagaaac gccgggcgcc ctggttgtcc gcgagcaccc
     5821 acagcagaac ggcccggaac tcctggctct ccatgagcgc gtgtgcctcg tcgagcagcc
     5881 ctcggccgat cccccggccg gtcaggccgg gacgcacgta cagcgcgttg atctcccccg
     5941 tgcgcacgtc gggcaccgcg ctccgggacg gcccgtagtt gatccatccc accggttcgc
     6001 ccccgtcgac ggcgacgagg tcgaccgacc gccggtgcgg cagcgagaac cactcccgcc
     6061 gccgggcggc gtcgtcctcg accgtcatgg cctccaggta cgaccgcggc aggatgcctg
     6121 cgtacgcgga ctgccagccc cgcacgcgta tcgccgagac ggcttcgaca tcggttccgt
     6181 tcatcttccg cacgtgcacc atcacgtcac cgtacgtccc ggggcacggc ggcaccacga
     6241 cgccgctgag gcccccagcg gatgacgcgc gaacgacgaa cgccggggtg ccatgcggca
     6301 gttcccggcg tcacgtcgag ggcgaggaaa gcgaagggac tagtttcagg agtgtgagaa
     6361 ggaagtccgt tcatggcctc gccggactca accgtagcag tcactccggg accaagtcgc
     6421 ccaggttttc cggggtgatg acgcacgagt cgggatgcag tccgtccggt cgctccagcc
     6481 cgatgtacgt cacggggccc tgcgggaccg tcctgccgtc ccacagcgtg gtgacatcgc
     6541 cccggtcggc catcaggccg gtgaggtggc gcaccgtgag gtggtcgcgc tcgacgaagc
     6601 cccggaccag ggccgcgacc gacaccctgt tcccctcgac ccggttcgcg ctcggggttc
     6661 ccttgaggta cacgtggagc cacttcgcgc gccagcgtcc gtcctccccg cgtatgaagg
     6721 ccagcggcag cgcgacgcgc cccggaccgc gcaactgcga cttcatgcgt acggtacgcg
     6781 gctcgaaggg gcggccccgc tggtcgccct cgcgcagcat gaagccgaag aacgactcct
     6841 cgacctcctc gaagccctcc cccgagaaga tgttgacctg cggaacgatg taggtcccgc
     6901 gcacggcccc caggcgcagg ttgatgaatt ccgacgcccc gtcgggtgcc tcggtgatgt
     6961 cgccggagtg ctcgccctcg acctcggtga gagccgtgta ggagagccag gagacggtct
     7021 cgtaggcgga gttgagcatc agcgccgaga ggtcgaagtc ggtggtgtcg ctcgtctgct
     7081 tccagtacac gaagaaccgc agcagttcgc cgtcgaccgg cgagagggag ccgcgcggca
     7141 gcacaccgaa cccgggcgcc gtcgccctgc cgctgagcgg gagcgccaca tcgaggacgt
     7201 ccggatcgat caacaggtgc cccggcacgg gcagtcggcg gctcgtctcc gcgtcgagtg
     7261 cggccaccag gcgggcccgc accgcctcgg gcagcgggga gcgcgactcg tcggtggccc
     7321 aggcgcggcc gaggcggttg acgaagacgc ggcgcgcacc gcttccccgc gcccggttgt
     7381 ggaagtgctc gcgcaccgac aggaggaccc ggcccgacac ctcaggggcc aggcgcgcgg
     7441 ccacgccggc caccgcgtcg cgttcggcgt ccgtggcgca ggcacgcagc agccggtcga
     7501 ggcagcggaa gagcttgccc ggagccgact ccaacagccg tgccgcgccc aggacatcat
     7561 cggccgcgag cagttcctcg acccggctgt cgaaggaccg ggcccgcttc tcgccccggg
     7621 ccaccgcgaa cacatcggcg gcgtgcggcc agcgggccgc gtactcgtgt gcgtgcagcc
     7681 gctcccccag gcgcttgaac gcctcgcgat gcgcggatac gtcggcgagc ttcgccgggt
     7741 tagccgcgac cacggcgtcg agtcccgcga gcagcacgcg gcgaacccgt cgggacggcg
     7801 agcggaaccg ggtcggctgc accagcgtga catcgccgtc cgacaggcca caggcgagcc
     7861 ggagcacatc ggtgaccgtg tcgagcagcg gatccgctcc ggcctctact cgggcacggt
     7921 tcactacggc tcggttctcc cgcaccggga tcgcctccgg ctggggcccg tgcacacagt
     7981 gcccggcgag cacctccagg tcgggcaggc ccccgtcacc cagcggtgcg gcgctccccg
     8041 cgagggccag atacagggcg gtgatctcgt cgtccggggc gccacccagg tgaagcaccg
     8101 tcagacggtc gcccgcggcc gcgagcaact ccccgtgcgc tgcgagcagt tcggcgtagc
     8161 tgtgctggta cgtgccgtac gccgggaggg tcagcagatc gaccacgccg tcgctgagcc
     8221 ctgcgaccgc gacacccctg tcgaccgcgt cggcgacgca ctgctgccag aaggcgtagg
     8281 tgtccggcac atgggccggg aagtcgatga agtaggcgtt gtgccggacg tggtccccga
     8341 ccatcgcacg gaccgtgtcc agggtgcgta ccgccgtgtc gacgaccgtc ccctccgaca
     8401 gcgccgacag gtgtccgagc agctccgccg acagcttgaa gcccacggac atcagcgccg
     8461 cgtcgaactg ccgcgcggcg accccgcctt gtccggcggc tccgcacggg gcgggcagac
     8521 ggtgggtgtg ccggacgacc aggggttcga gagcgtggac catccgggca tgttcccaga
     8581 gcccgacgaa ccggcgcact cgggttttcg cacggcggcc gtcccacccg ttccaggggg
     8641 cggcctggtg cccggcccac cggtcgcagg gggctggggg ccaggtgccg tacgcggctg
     8701 cgtgtgaacg tgacagaggg ggaaggggtg ggaggtgtgg gagttcactg atcctctgtt
     8761 cgatttcgct cgccgccgcc gtgagcccgc ggtggtgcag accctgcgtt ccaccgccgc
     8821 cgcggtcatc tcctacgtcg tggcccttca cctgagcagc gagcccgcgc ccctcaccgc
     8881 cccgctgacc gccctgctcg tcgtgcaggt caccctctac accacgttgg tgactgccgt
     8941 gcgcagggtg aactccgtcg tggtcggggt gctgctcgcc gtcgggttca gctccctcgt
     9001 gggcctcacc tggtggagcc tgggactcat catcctggcg gccctggtgg tcggacggtt
     9061 cgtcaaggtc ggggaattcg tgcccgaggt ggccatcagc gcgatgctcg tcctcggtgt
     9121 cacccgggtc tcggccaccg cctgggaccg cgtgctggaa accctgatcg gcgcgggcgt
     9181 cggcatgttg ttcaacgtgt tgctcgcacc cccggtgtgg gtggattccg cgggcggtgc
     9241 catcgaggag ctcgccgcgc ggatgcggcg gctgttggtc gacctcgggg acgaggtcgg
     9301 cggccacacg ccggtggcac aagccgccgc ccgcctccac gaggcacggc ggctcgacca
     9361 cgacatcgcc caggtggacg cctccctgcg gcaggccgag gacagcctca ggctcaaccc
     9421 gcgcgtcaag gaggggctgc tgtcccgcgt ggtgctgcgc accggcctcg acaccctgga
     9481 gatctcggcg gtggtgctgc gagtggtgtg ccggtcgctc acggacctgg cgaaggagcg
     9541 gacggaggag cacctcttcg acccggaggt ggggctcgcc ctgcgggacg tcttcgagca
     9601 tctcgcccgg gccatcgaga gtttcgcggt cctcatcacc acgcaggtca gtaccaatgc
     9661 cgaggaggcg gagcaacggc tgacggacga gttgacggcc ggccgagcca gccgcgaccg
     9721 ggtcgccgac ctgttgctcg ccgaggtgca gcgccacccg aggcagtggc agctgcacgg
     9781 ggcgctgctc gccgaggtgg accggatcct cgacgaactc gacgtggaga agcggtccca
     9841 gcgcctggtc gaggagctgg accggctgtc gcgggaacag cggcggcggt ggcacctcct
     9901 gcgccgggtc cgcagccgga cccagcaggc gctgcgcctg ccggaacccg aggaccggcg
     9961 gtcctgacgg ccgacggccg gtcgggcccc cggccctgct tcagtcgagc agcagcgggt
    10021 tgggcaggtc ggcgtcggga tgcatccgca acagggtgtg gacgactcct gccaggccgg
    10081 acatgaggct gggcgagaac gcctcacggg cgaggccgcc gaccgggccg cgctgttcga
    10141 gcccgctgag gatctcggcg tcgaggtccc tggcatcgcc cgatccgatg gaagtgagga
    10201 actcccagag acccagatct ccgtggcaca gggtgtggct ccatccgaag ccctccgcgg
    10261 cgcaggcccc cgcagcccgc cgggccatgt cgagatgagc ggggtcgccg gtgcggcggt
    10321 ggaggtccag catgccgatg ccgatgcccg cgctgccgtg gcaccagctg gtgaagaagt
    10381 cctcctccgc gccgacgcgc acgtcgagcc agttgccgtc ggccggccgg tagagggact
    10441 cctggaaggc gaaggcacgc gcggcgaggc ggttccagtc atcgcgttcg gccgcggagc
    10501 ccgcctccga gagcgcgagc cgggtcagtg cccagccgat gccggtggcg ccgtgggcga
    10561 agccgccgat gccctcgggg ttgaggcggg tcggccagcg ggctcccccg gtgtcggaca
    10621 cggccagctt gcccagccgg tggccgatgt gcgccgcggc gtccagccag cgtgtctgcc
    10681 cggtcgccgt ggcgaggtcg agcagcggga cgaccgctcc ggcaacgccg ttgaggaggt
    10741 ccacctcgac gtcctcgtcg accagtggtc cgccggtgag cagcagggcg cgctcggcgg
    10801 cccgctccag catccagtcg tcgccgagca cccggtgcag cgcgagccat gtccacacct
    10861 gggacgccgc gccgctgaag gccccggccg acggcgtcgg cgtacggtcc tcggtgctga
    10921 tcagtacgcg cagcgcgccc tcgaacgtct cgcgcacgcc cggcacttcg tccgcccgcc
    10981 cggcccgaac ctcgcaggcg tactcggcca gtgtgagcgc cactccgccc tggccggtgt
    11041 agaggtcggc gggcagcaca cggatcgacc agccggccgg gctgaagacg gggctgatcc
    11101 aggtgaccgt gccgtcctcg ccgcgcaccg cgccgtcgct cagccgccgg accatccgcg
    11161 cggccagttc acggcggcgc cgctcccggt cgcgggcgtg cggggcatgg gcggcttcct
    11221 gcacccgggc cggcagcgag cgctcgttca gatacgcgcc gacgagcgcg tcctggatca
    11281 ccgactcctc gaaggccagg tcggcgtcgc gccagtcctc cacggtggcg cgcacggccg
    11341 cggcgtcgac ggtgaagttg aacatcggca catcgcccac cagcagatcg gcgatctcgc
    11401 cgtcgatcgt ggcgcggtcg gtcggcgcgc cgggcagcgc gtcggcgttg cggcgcagga
    11461 tgtcccgggc gcgctcgacc gccgccgcct cgtcgtgcag cgaggccggg tgccacagca
    11521 tgcggccgat gtcgacgtac gcctgggtgg gacgcaggat gcgccgggcc cgggctcctt
    11581 cgaagcgggc gagaagccgg tgcgggtcga ggccgggccg cctgaggtgt gcggtcatct
    11641 cgcggaatcc ggccaggacc cggtcccagt aggtgctcag gaccggagtg gcggcggggt
    11701 ggttgcccgc tacgggcatg gccaccaggt ccacctcgaa gcgggccgtg gcggtgcccc
    11761 cgtcggcgat caccgggtgc gggatcagcg gctgctgccc gggcagcgcg ccgatgccgg
    11821 agatgtcgac tccgccgagc gcgaagccgg tgccgcgcac gggcagcagc ccggtgcgca
    11881 gcacggtgcg gcggatggcc gccgccgcca cgtccaccgc gtcgccgcgg ccgctgggcg
    11941 ggaagggggc cggggcgtcg aagagcgtct cggcgtccac gatcaccggc acgggcccgg
    12001 cggcgatcat gttctcggcg tgcatgtcgg tgccgccggt gaaccggagg acggcgagcc
    12061 agtgcccgag attgcggtag aacacggcga gttcggcccc gtccgcgcag taccggtggc
    12121 cgatgaactc ggcccagccg tacccgtcgc gagccagagt cgcggggacg cggatgcgcc
    12181 ggtccggcgc cggcgcgccg gggaggccgg tgaacaggtc gtccaggagc gcacccagcg
    12241 ccacgtcggc ctcggacggg cggggcttgt acatcacggt gcccccggcg aagtcgaccc
    12301 ggctgacggt cagcccgccg tggtgcgagt ctccggcccc gaacgcgacg gcccgtaccc
    12361 ggcccgcggg tgcgccgagg agcggcgcga ggagatcccg gtccgccgcg aggcgctcgg
    12421 cgaactccgc cgtggccgtg accgagagcc gtgccaccgt ggcgatccgc cgggcgaggt
    12481 tcgggtaccg gtcgctcagc ccgtcgaggt agccctccgc gccggcctgc tcgacgaagg
    12541 cgtcccagat cgctcggccc gactcgctac cggaggcgga gccgggacca ggggcggcac
    12601 cggccccggc ggccgggccg gagagccgca gcgcgtgcag ttcgatcagg aacaggcggg
    12661 acagcttcgc gtgcagcgac cggagcaggg ccgtgtgacc ggcctcaagg atcacgtcgc
    12721 gttccgtcgc gtccagggag ggcaactcgg ccagggcgcg ggccagttga tcccgccagg
    12781 ggcgggcgat gctccgtacg ggccgagcga agtgctccgt ctcctccggt gcccccggca
    12841 ccaccgcgtt cgccatcaac cgtccccgtc ccaccacgag ttcgcgcccc gcgaggcgcc
    12901 tgaagggccc gcgaggcggg cggtcggtca ggcggcgggc ccctcgcggg aagtcgctcc
    12961 acgaagggcc cgccgggtgt cttgcacgct cagcaacacc agctcccgtg cgacccgctc
    13021 gggctggagc agaagccgta gagggagtca ctggagtcgg tgagcgcggc ctcggcggcg
    13081 gcgccgccga catagagcgg accggccggg ttgagctggc cgtacgcgct ttcggcacct
    13141 gagagccagg cgttgagcac ggcacttgca ggaacactgg tctgcggcat cagcggcctc
    13201 cggacagagg gatcgggacg gatcgcccag ccctgagtat ggccatgtcc gaacacccgt
    13261 cagatgcgga atccagccaa agtcacaggg gcggagatgc gcggcacacc tgtcgtccgg
    13321 gcaggcggcg gggcggatcc gatccccgcg aaggcacccg aatcgggcgg tggcatgatc
    13381 gatgctcgac atgcgcccgc cccagcctgc cctccggcaa ccaacacatc ggcagaacaa
    13441 ttgatacctg gactttcacc gagaagcgca cgaatacgcc acgtcatcga gtccgccccg
    13501 tggcgccggc cgcgcgtggt gctgtggacg gcggtgggcg tggtggccct cgcgttcctc
    13561 atcggcctgg agatcaccgc gcgccactac ggcgagcggg ggccgctcag cacccaggtg
    13621 cgcgaggtgt tgttcgcgcc gaagcccggg cccctgtacg gcggtctcgc gctgatgatg
    13681 gtggtgctca cctggcgaca acggttcgtc gctgccggtg tggcgatcgg tgtcgacgcc
    13741 gtcttcgtgc tcggccggtg ggcgtgcggc gtccgggtgc ccgaggggca cctcttcggc
    13801 aacggcgcgc tgtgggcgat gctgggctgt gcggtcttcg cgatcacgcg ccgcaccggc
    13861 accgaacggg tgctgctcct gaagggcgtc ggactcgggc tgctcctggt gaccggccgc
    13921 aagatcggtg acagctggct gctcatcacc tcgaagacct gccccaccgt gctcgacccg
    13981 tacgtggcga cggcggatca cgcgctgggc aacccgtcat ggctggcggg ccgcgcgctc
    14041 gacgccatcg gcccggcggg ctccaacctc ctcggcctca tctacgccca gctcgcggtg
    14101 gccgcgatcg tggtcgccct gtaccagctg cgcaaggtgg cggccgagcg ccgcttcccg
    14161 cgccaccacc tggtgcgcac cttcctgctg atcggtctcc tcggaccggc catctacatg
    14221 atcttcccgg tggtcggacc ggtcttcgcg tacgggcccg gcgcgtccgg caccggcggc
    14281 gtggagtggt cggtggccaa cctgtggccg cacacgccgc cgccgatcgc gatgccgcac
    14341 ccggtgccgt acgacggcat caccccgcgc aactgcatgc caagcctgca caccgcctgg
    14401 gccaccgcga tcttcatcca cacccgcacg ggcccccgac tcctgcgcta cgcgggcacg
    14461 ttctggctga tcgccacgct cgccgccacg ctgggcttcg gctaccacta cggtgtggac
    14521 ctggtcgccg gggtggtgtt ctcactcacc gtcgaggcgg ccctgcgcac gttcgaccgc
    14581 ggctgggacc gctcgggact gcggctggtc gcccatggca cggcggtctt caccctgctc
    14641 ctggtgtcgt accgctggct cccggtccac atggccgccc gtccctggct gttcgggccg
    14701 ctcgtcctcc tggcgatggg ctccgtcatc cacggctacc tacgcaccac caagcgctgg
    14761 acgagcccgg acgccgcccc ggcgctgctg ccggaaccac agcccgagcc ggtctgagcc
    14821 ggaccccggg cggggccggt ccttgtcgcc gggggcgaca gggagcacga tggagacaga
    14881 acggaggcag cacctccgca tcgccggagg tcgttgccgc acagccatcg cagtcgcgcg
    14941 gaacgacgac tgccgtggcc gcacccaccc ccgtccgcac agggacagcg gaaccgtccg
    15001 ccggcgggtg cggccccttc ctgccgggcg cggcagctca cgcggcgggc caatgccctc
    15061 accgggccgt gtacgggccc ggccaacgac cggaggactc gatgtccctc accgtcgtca
    15121 tcatcgtcat cgccgtcgtg gtggtgctca tcgcgtgtgc ggtggcagcg cgcctggcca
    15181 cggtccggcg ccgcaggctt caggagcggt tcggcccgga gtacgagcgc accgtggacg
    15241 agcaggacag ccgccgggcg ggtgagcagg agctgcgtga gcgccaggag cgccatgacg
    15301 cgctggacat caagccgctg cccgccgccg cacgcgaacg ctactcccag gactgggccc
    15361 gggtgcagga gcagttcgtc gaccggcccg acgacgccgt ccacgacgcg gaccggctcg
    15421 tgaccacgct catgagcgag cggggctacc ccaccgaagg gtacgagcag cagctcaagg
    15481 acctgtcggt cgagcacggg gagaccctgc agcactatcg cgcggcccat gacatcaacg
    15541 aacgcagcgg ccgccaccag gcgaccaccg aggagttgcg gggcgcgatg gtgcactacc
    15601 gcgcgctgtt cgaggagctg ctccacaacg gggaccggcc gggcaggagc acgacatgag
    15661 tgcacgaccg ccgcgggtgg gcgccgaacg ggcccacccg tcgcggacca cgacgcgtga
    15721 cggacggagt gaagagatgc gctacgagga gacgccccga cccgacgagg gcccgctgtc
    15781 cacggaggat ctcgccgccg gcaggcagca ggacaccgga gccgaggcac cggggccggc
    15841 cggtggagca ccgacgtacc ccggagaggc cacggccggc cgcgaggacc ggcaggagga
    15901 cgccggcgac cgggcacccg ggcacgcgcg ggcggaggcg gagcctgcgg aggacgacga
    15961 acccctcctc ggctcagagc aggaggagtt ccgggccagg tggcagcaga tccagagccg
    16021 gttcgtcgac gatccccagg attccgtcaa cgccgccgac cagttggtcg ccgagacgat
    16081 gcaggcgctc gccacgacgt tctcggccca caagcgcgat ctggagggcc agtggcatcg
    16141 tggcgaggag gtgccgaccg aggacctgcg cgtcgccctt cagcagtacc gctcgttctt
    16201 caaccgcctg ctcagcacct gaccgccgat cacaagctca cccggtcgcg tcccggcgcc
    16261 gccgctcgcg tgacgaccgc cgccacagcc gcgccgacgc acacagcgcg gacaccgcga
    16321 agagcgccgc cgtcaccagc agccagcggc cgaggaacac atcgctcggc agcgcggtgg
    16381 cggcagtgaa gccgtcgacc tgtccgagga tgagcggcca ccacaccaga agcagcaccc
    16441 cggagacgaa cgccgggacc cggacgtggt tgacgcccac cacgcggtcc cccaccgggt
    16501 gcgcaccgct tcggcccgtc gcgggcagga ggcgctgcag ggcgcggtcg gccgtcgcgt
    16561 agagcggaag gagcaccagg tcgtgcagca gcgccgcgcc gacgaaccag aggacgactc
    16621 ccagtgtgtc gccgcgcagg aggcgcaccc ccgcgtagag ggcgagcgcg aaggagcaca
    16681 ggaccgccgt cagatgcagc ggggaggctc cgtagcggct gcggaagcgg ttcacgtcgg
    16741 ctctccgaag gtgaggcgcg tgacccactt ggtgtggtgg accccggggg cgttcgggac
    16801 gacgatccgc gcggggtaac cgtgatccgg ggagagggcg gccccgttga cctccaccgc
    16861 gaggagcgag cgggtgtcgc gtacctggtt ggcggccagg accaccgagc cgaaggaacc
    16921 gccgcgctgc accgactcca ccaggacccg cggcgcgtcg tgggtcacgc ccaccagcgc
    16981 cgcgagatcg acgaggcgta cgccgcccca ccgctggtcg ggcgtggacc agccctccac
    17041 acaggcgatg gggagctcga ccgtccgcct cggcagggca tacagctcgt cccgggtcag
    17101 tacggtcttc cgaccgccgg cccggacggt caggcgccag gaggggccga tgtcgctggg
    17161 ccggacaccc accgaggcgg cggtcttgtt gatctggaac ccgttcggcc cggaacccgg
    17221 gtcctggccg tgcggagcga gcagcgcggt cctgcgcatc cagccgccga tgctctggcc
    17281 catcgtcacc acgagcaggg ccgccgaccc cgcgcccacc agcagcacgg cgccgcgacg
    17341 cgacatcgtc ggctcggccg ggcggggcgc gacgaggccc ggcccggccg tggcgagcgg
    17401 ccgcgcccgg tgctgctctt ccgcgcgcgg gcccttcacc accgcgatca cggcccgcct
    17461 gaggcggaag acgacatgca cgacgaacgc gccgatgaac acccacgccc cgtagaagtg
    17521 cagtacgtag aaggaacctg gaaagacgta gtgcaactgc acgttgagga cgccggtggc
    17581 gaattcgaag ccggccccac ccacgaggag gagcagggac agccgctcca gcgcatggcc
    17641 gaccgagcgc acgggcggcc actcgaagag cctggggatc accgaccaca acttggccag
    17701 gagcaccggg atcagcacga tgccgagtgt gacgtgcaca ccctggctga gccggtaccc
    17761 ccagtacggc gacgtgggcc aggtgaacag gtagaagccc agcaccccct tgtccggggt
    17821 ctggtcgttg atccgcgcca ggtcggggtc gtacgccgcg tacgacagca gcccggtcac
    17881 gaacaggacg ctcaccccgc acagcagggc cagaccgaac acggctgtca gccacgggcc
    17941 gcggatgggg ctgcgccaga actccggccg cgccggaccc ggaggcggtc ccgccgcgac
    18001 ggccgcacgc agccgccgcc atccgcgggg ctcgactcgc ccggaatcag cgggagttga
    18061 cccaccgtgc gccgacgcac ccggcgcgga ggcacccgga gccgatgccc gcgaagagga
    18121 gtcctgcggg gcggagttct gcggggcgga gtggggatcc tcggggaggg gctggtcgct
    18181 tcggccgcca tccatgggaa tcccctgttc caccgggcgc cgaccgagcg ccgcgcgttc
    18241 caggtgaaac ttccgcctcc ggcccgcccc ggcgcgctga cactccgcac acgcaccgca
    18301 gaggcagccg aacggcccag cccgccggac cggggcggcc gcctccgcct cctcagacgc
    18361 tgcggatgag cgtgacgagg tccttgcggc ccgaggccgc tatgagggcg gcgtcgtcgg
    18421 cggaggcagc ggcgatactg acgcgcgccg cttgcaccgc ctgcaccacg gggttggtgg
    18481 cgccgccggg ctcggcccgc ttctcgttga gcttcttcga gtccaggtag tcataggtgt
    18541 cgccccgccc gcgccgcgcg gtgatcgcct cttccgcgcg gcgcacatcg cgggcggcga
    18601 cgtagtcggc ctgggagacc ttcgaccaca ctcccgtgcc accggtgacg aagaagtgat
    18661 tgggcgagcc gttggggttg aggccgctgt tgtccaccag ataggtgcgt cccgaaccga
    18721 ctgtcagggt cttgccgaac agggccttcc agctgccctt ggccttcgcg agcaacgttt
    18781 cgacctgctc gccgacctcc acggcctcgg ccgtgacggt ggcgtcgtcg acgctcgcgt
    18841 acagcaggct gttgatctcc ccggcgaccg tgctggtggc gcagtgccgg taggagtggc
    18901 gttgcaggga catgtccagc cggagcggcg tcgcgccctc gacgttgacg gtgacgacgg
    18961 ctccggtgat cgatgcagtg gccatggcga agctccctcg cgggccggcg ccgggcccct
    19021 gatgggcccg ccgagctcgg cttcacatca cgaccactat gccaagatcg cccgaacagt
    19081 ccccgcatat ccactgattg agtcacatgg tctgcgaccc cgtcctcaac tcggcgtaga
    19141 cgcctgcacg ttgatgcctc agccgttgaa gcggtccgga tcgggaccgg tccgctcgtc
    19201 gcggttgagt gcggagatct caccgagatc gccctcggtg agctcgaagc cgaacaggtc
    19261 gaagttctcc tcgatgcgct tctgcgtcac cgacttgggg aacacgatgt ccccgcgctg
    19321 gatgtgccag cgcagtgtga cctgcgccgg ggacttgccc acgcgctcgg cgatccgctt
    19381 gatggccggg tcgtcgagca ccttgccctg cgcgatcggc gaccacgcct cggtggcgat
    19441 gccgtgctcc gcaccgaagg ccctgacgtc gtcctgagtg aggtaggggt gcacctcgat
    19501 ctggttgacc gcgggcacga ccacgccgct ctccatgagc cgacgcaggt ggtggggctg
    19561 gaagttggag acgccgatgg ccttggcgcg cccggagccg tagatctcct ccatggcctt
    19621 ccacgtctcc gtgaagtcgc ccttgccggg cagcggccag tggacgagga agaggtcgag
    19681 gtggtcgagg ccgagctcgt ccatggtgcg gtcgaacgcc gcgagcgcgt cgtcgtgcgc
    19741 gtgggcgtcg ttgttgagct tgctggtcac gaagacgtcg ccgcggtcga gcccggaatc
    19801 ccggaccgcc tgcccgacct ccttctcgtt cccgtacatc tgcgccgtgt cgatgtgccg
    19861 gtatccggcc tccagcgcgg ccagcgtggt ttcccgggtc tcgtccttcg ggatctggaa
    19921 cgtcccgaag ccgagctgcg ggatccgcac accgttgttg agggtgatcg tgggtactgc
    19981 cgtcatgctg ctctcctgat ctcgtgaccg gtgttgttga tcgatgtcgt ggttcggggc
    20041 ttcgcggccc gggcgttcgc gctcgggagg atcagccggc gattccgcgc agttcggcgt
    20101 cgggcggcag gacgcggacc agcttgcggt tcacgaactc ctgcatgccg agcttcgaga
    20161 gctcgcggcc gtagccggag cgcttgatgc cgccgaaggg gaggtcgggc tgcgtcgacg
    20221 tcgggtggtt gacccagacc atgccggtct ccacccgctc cgccaccttg cgcccgcgct
    20281 ccacgtcggc gcagaacacg gttccgccga ggccgtactg gctgtcgttg gccagcgcga
    20341 tggcctcctc ctcgtcggcg acgcggtaga tcaccgcggc cgggccgaag agctcctcgc
    20401 cgtaggcgcg catcccgggc ttgaccccgg cgaggatggt gggctcgacg aaggcgcccg
    20461 ggcggtcgat ccgccggccg ccggtgacga gctccgcacc ctgctccacc gtctcgcgga
    20521 tctggtcgac cagatcggcg gcggcccgct cggaggacaa cggacccagg gtggtcgact
    20581 cgtcggcggg gtcgcccggc cgcagttcct cgaacgcgcg gcgcagaccc gccacgaagt
    20641 cgtcgtagac gtccgcgagg acgatgaagc gcttcgaggc cacacagctc tgcccggtgt
    20701 tcgccatccg gcccgccgcc gcggcgccga cggtgcgctc cagccgctcc ccgtcgagca
    20761 cgatgaagac atcgctgccg cccagttcca gaaggctggg cttcatgttc cgcccggccc
    20821 gttcggcgac ctgcgcgccc gccttctcgc tgccggtcag cgaggcaccg cgaacgaccg
    20881 ggctgtcgat gatccgcgag atctcctcgt ggcccacgaa cagattggtg tagacgccct
    20941 cgggagcttc cgcgtcgaag aacagcgact ccagggcgag cgcggactgc gggcagatcc
    21001 cggcgtgctt gacaagcacg gtgttgccga gcaccaggtt ggggccggcg aagcggacca
    21061 cctggtagag cgggaagttc cacggcatga cacccaggag gacgccgagg ggctcgttga
    21121 ggaggtacgc ctcgccctcg tcgacgtcga gcggctcggc ggcggcgaag tgagggccgt
    21181 tctccgcgta gtactccagg atcgacgcgg cgaggtccac ctcgccgcgc gcctcggcga
    21241 tgagcttgcc catctccagc gtgatgagct gggccagctc ctccttgcgc tcgcgcatca
    21301 gggcgccggc ccggccgacg acggcggccc gctcctcgat cggccgccgc cgccatgcgt
    21361 cgaacgcacg gttggccgct tcgagccggg catcggcctc ttcgccctcg atggcatcga
    21421 actccgcgac ggtctccccg gtggccgggt tcacggtcgc gaacgagctc ttgtgctggt
    21481 ctgacatgca atctccagaa cggtgaacgg ggaggaagtg cggcggaatg gcacgttccg
    21541 tccctgtcac gggtaaccgc cttccggtgg cgcaaaccgt cctggatcgg ccgtggcgcg
    21601 gtggcccgcc gcgaggccga gacgcctcga ccccgccccg gtgccgacga gagggccggc
    21661 accggggcgg ggtcgaggac tacgggctca ccggggtccg tcgtgcggat cccggccggg
    21721 ggtgcgtcag gagttgatgc aggtggtgcc ggcggccggg ttgagggcgc cggccacgct
    21781 gatggtgttg ccgcagatgt tgatcgggat gtgcaccggg atctggacga ggttgccgga
    21841 ggcgacgccg ggcgagtgag cggcgacacc ctgtgcaccg gcgtcggcga cggcactggc
    21901 acctccggcc aggacaccgg ccacggcgag ggctgcggcg gcaatcgcgg ttcgcatacg
    21961 catgtctgtc tcccacatga tcgaaagaac gttgagccga tatgagaccc cgcagcatga
    22021 tcgaaaaagc cgcattcacc acaccggtcg cgtgtcgccc tcgacgagtg gtggccgtcc
    22081 cccggtccgg gtggcggctg gccgcacacc ggtatgcaat ggtccgcgga gggtgcccac
    22141 catggccagg aagcacgagg cgcgggacgg gctgagcgag tacgcccgca agcgcgactt
    22201 ctcgaagacc ccggagcccg agggcgaggc cgcccggggc aagggccggg agccggtctt
    22261 cgtggtgcag atccacgacg cgagcacggt gcacttcgac ttccgcctgg aggtggacgg
    22321 ggtgctgaag tcctgggccg tccccaaggg gccgtccggc gacccgcacg acaagcggct
    22381 cgcgatgccg accgaggacc acccgatggc gtacgccgac ttcgagggcg tcatcggcga
    22441 gggctacggc gccggaaccg tgatcgtctg ggactcgggc acctatcgca gcctggccac
    22501 cgaccgccac caccacgagg tgcccttcgc cgaggcgctg gagcacgggc acgtctcgtt
    22561 ctggatggaa ggcaccaagc tgcgcggcgg ctacgcgctg acccggatcc ggcgcccgcg
    22621 ggacggcgac cgcgaggcct ggctgctggt caaggaggac gacgggcacg cctccgcgca
    22681 cagcacgacc gagcccaccc gcgcccggtc cgcgctgagc gggcgcaccc tcaagcaggt
    22741 cgcggacgag gcggcggagc agacgtcgcc gtgagcgcga cgccacccga ctcacaacct
    22801 cgcccaactc gctctacccg taagcacatt gacgcccccg tcgaccgcct cgcgcc
//
