LOCUS       NZ_BMUU01000001        21074 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence01, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000001
VERSION     NZ_BMUU01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1270804)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1147766
            Orig. end                         :: 1168840
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="13"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(1511..3004)
                     /db_xref="GeneID:96289058"
                     /locus_tag="IE233_RS05045"
                     /old_locus_tag="GCM10010326_10490"
     CDS             complement(1511..3004)
                     /codon_start=1
                     /db_xref="GeneID:96289058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524494.1"
                     /locus_tag="IE233_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10490"
                     /product="hypothetical protein"
                     /protein_id="WP_161244548.1"
                     /transl_table=11
                     /translation="MSGQPNTRLNDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGETPRDPVPRVLAALFTERLGRVVTIEDLGFDRHGRAGKRNDVRNIKNPDGL
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALATGSVLSSAMHDWLHTDPVLSADAPR
                     LHDPLHADPAGFDRYEAAPIGSQEIDALERSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDIGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPGEALDLMKLAKSGSGEETLPRTRAMLHTIEAWAQASMGRGQA
                     MRRTLGEAEELFVSDKGDVPPPSWMQMFDEADLHGMEALAFRTLAEHDPAAATIAQHHA
                     KQALELRVGGRQRSKIFDYISLASACFIADDPEQADRYARLALVSMGETSSHRTWDRLR
                     EMYRLTNQYAGHGKIQDLREEIQQALPQAPLKRSRVADI"
     misc_feature    3169..3183
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            3238..4368
                     /db_xref="GeneID:96289059"
                     /locus_tag="IE233_RS05050"
                     /old_locus_tag="GCM10010326_10500"
     CDS             3238..4368
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96289059"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="IE233_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10500"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_161244549.1"
                     /sec_met_domain="APH (E-value: 1.7e-16, bitscore: 57.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSTPPRPHRPLGAGGGPYLDPTHAGSAYGAGRMPRRPG
                     AAPQPLSGRIDLSGPQGAQLRIAIASVQRICPEFNPVQVLRHSGRSVLIVGTTGRTTAV
                     AKCLLDHSPAWAERFRHEIAAYRAFVRHRPPVRVPRLIAADPDNCTLVIERMPGRAAAL
                     TRHPVEAPPRADVRAALGAIGRVNAWRPPAEMFGRPLDYAPRIARYHELGLFTDRDLSD
                     LQKLIHGLALSGRVDWQFSHGDALLSNILLSPAGPVLVDWEHAGWYLPGYDLATLWAVL
                     GDAPVERRQIASAAQAAGPAARDAFLVNLMLVLTREIRTYETAVQRTMRDATPSSPVQN
                     APGVLSAGEQQRLLLRRLHDDCALARRAVRAAVGTR"
     misc_feature    3559..3561
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4463..5791)
                     /db_xref="GeneID:96289060"
                     /locus_tag="IE233_RS05055"
                     /old_locus_tag="GCM10010326_10510"
     CDS             complement(4463..5791)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96289060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018102934.1"
                     /locus_tag="IE233_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10510"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_189765085.1"
                     /transl_table=11
                     /translation="MTSKQRIRLALATATAGALGLALAPATAASAAGSGTECPRVLKCD
                     WVPAAYQQTGDPANKEAYGNYDVSDRPNTNRIKYIVLHDTEETYATTLKIFQDPTRAAS
                     AHYVVRSGDGHVTQMVKTKDVAWQAGNWYINSDSIGIEQEGYATEGATWFTPAMYRSTA
                     ALVRYLADKYDIPLDRQHILGHDTVPPTTAGGTAAMHWDPGPYWDWNYFMGLLGRPTEQ
                     TGRPGGQLVTVNPVFKQNVQAFRDCEKNIDLPAQPSSAVPLYTQPSTTAPLFADPGLHP
                     PGQSGTNCAGDWGSKISATQQAVVAERKPGWTAIWWYGQEAWFQSPAHTRTATATAGYV
                     VRPKRGRTDVPVYGTAYPAAGDYPADFTAPRVSTPLAYTIKAGQSYPGGEPTPTGYYYA
                     PTIDSSYPYDHTYFPGSTRYVTVQIGHRIAFVKASDVDVVRVR"
     misc_feature    complement(5917..5932)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.55"
                     /tool="antismash"
     gene            complement(6114..6614)
                     /db_xref="GeneID:96289061"
                     /locus_tag="IE233_RS05060"
                     /old_locus_tag="GCM10010326_10520"
     CDS             complement(6114..6614)
                     /codon_start=1
                     /db_xref="GeneID:96289061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849642.1"
                     /locus_tag="IE233_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10520"
                     /product="hypothetical protein"
                     /protein_id="WP_161244551.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLFGGRGPAMIIGNLPAGSPAREMAEGQVPFEVAQLLVALENDEPIEVVGTEDM
                     PVMQGDNLLIVRRLKLSESRISCVQFDRSDDVLVTIASWDRPITDDLYALLKPLPAELF
                     QQS"
     gene            complement(6808..9699)
                     /db_xref="GeneID:96289062"
                     /locus_tag="IE233_RS05065"
                     /old_locus_tag="GCM10010326_10530"
     CDS             complement(6808..9699)
                     /codon_start=1
                     /db_xref="GeneID:96289062"
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058744.1"
                     /locus_tag="IE233_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10530"
                     /product="AAA family ATPase"
                     /protein_id="WP_190026312.1"
                     /transl_table=11
                     /translation="MLFERDEELLLFDSMLDDLCGRAGEGSAPNGGLLAIAGSAGLGKT
                     TLVAEVRRKAAARGCTLLAARGSEQEEGVAFHVVRQLVQPVLAATSEEEHRKILGSWYD
                     IVAPAVGLVAGKSGVAPDPQGVRDGLDWLVTRFAVQYAPVVLVVDDAHWADEETLAWLT
                     SFALRAADLPLLIVVAYRPEELPRHAAEFRRLATRHGSRPLDLSPFTPAAVSDLVRDVL
                     GEGGDELFARECWALTAGNPYEAVELVARIRDRGIKPQYANATELRELASAVRGNGLIE
                     RLERLGPSAFRLTWAVAVLGTDARREMAAGVAGLGVEEMADAVGKLRDARILAEQSDDH
                     PDRLDFFHPLVGTAVYRAIPSAMRVAMHGQAAFAVSEAGLGATSAARHILEMHPENDRW
                     AVRQLRAAARDYLRAGAPDAARRCLARALREPPALEERAEVLFELGCSALLNEPATTVN
                     HLKAALEEPELAPELREAVTYRLAQALAHTDRMGEAAAIVGAEAKNSGSARTRLRMQAE
                     SFQWNAFRADEEDSPARSRSLARLAEHITGRGKAERYILGLRAWDAMVRGEPAETALRY
                     AEEALEGGLSWTDDNWGFEVPVLVALTFMYCDQPGRADELFTQGIADCERKGWRGAHLS
                     FGLTLLGYIKFHRGRLSEAEDLVHSGLRIADRVGHQVPAQWFALGILIEILLARGRVQD
                     AQELSDAYNYGQVVPNAVVYPDSETVYSELLIARGLRTDAEARLRAVGRRLEPRGMRNP
                     MWCPWRPLLAQTIAHTDPVEAAAIAQEGVEIARRFGTPGAVGRALHAAAKVTSGADSLA
                     LMSEAVRQLEKSPAAYELAQALIDHGAMLSRAGLPQDAADLLMRGLESAALCGADALAA
                     RAREELAASGLRPLQLRAVDSDSLTSQEKAVAERAAQGWENRRIAEELGTKERTVELLL
                     SGAFRKLGTNRDGLAGLLPHQSRGSGVRGVPGL"
     misc_feature    complement(9650..9665)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
     gene            10001..11074
                     /db_xref="GeneID:96289063"
                     /locus_tag="IE233_RS05070"
                     /old_locus_tag="GCM10010326_10540"
     CDS             10001..11074
                     /EC_number="4.2.3.157"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96289063"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173680.1"
                     /locus_tag="IE233_RS05070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10540"
                     /product="isoafricanol synthase"
                     /protein_id="WP_190026313.1"
                     /sec_met_domain="T1TS (E-value: 6e-86, bitscore: 285.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTGRVRSARMRTGLVDIPFPARRHPRDALARRHTLDWLYEFGM
                     LAGEQATAEYDAMGLERLMAYFYPDASDAHLALATDLNAWFFVFDDQFDGPLGKRPDVV
                     LRQIDTVLRTMSDEAPVAGETTNRLAESFRDLWQRVTAGTPLLWQDRFRAHWREYLTAY
                     HWEALNRTRNGTLSLPGFLRGRRDSIGVQPCLDLVERCGGYTLPRELHGGVPLAEMREI
                     TADVVIFVNDMVSVDKELAAGDVNNSVIILMRQEACTVEQALRRVAVMANSRIARFQEL
                     TVELAAQLDKTALPEQVRANVDDYVDGMRGLMSGNLAWSLETARYGEAGIAAVSEGRQR
                     PWARLFPEQATEEREGA"
     misc_feature    10436..10438
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11184..11450)
                     /db_xref="GeneID:96289064"
                     /locus_tag="IE233_RS05075"
                     /old_locus_tag="GCM10010326_10550"
     CDS             complement(11184..11450)
                     /codon_start=1
                     /db_xref="GeneID:96289064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713275.1"
                     /locus_tag="IE233_RS05075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10550"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_373300102.1"
                     /transl_table=11
                     /translation="MADTSTTQHTLRTLAGHTRSGWDKPELDLSQAEWQSSSQGAGDVQ
                     IAFVEGFIAMRNSGSPGSPSLIFSPAEWRAFVINARDGEFDLT"
     gene            complement(11558..12724)
                     /db_xref="GeneID:96289065"
                     /locus_tag="IE233_RS05080"
                     /old_locus_tag="GCM10010326_10560"
     CDS             complement(11558..12724)
                     /codon_start=1
                     /db_xref="GeneID:96289065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971158.1"
                     /locus_tag="IE233_RS05080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10560"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_161244553.1"
                     /transl_table=11
                     /translation="MSKEPVAVVGVGQTKHVAARHDVSIAGLVREAAQRALDDAGLGWP
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVASNLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFTQPLLAGAGGFFAPHVRAYMRRTGAPDTVGS
                     LVAYKDRRNALKNPYAHLHEHDITLEKVQASPMLWDPIRYSETCPSSDGACAMILTDRA
                     GAARSPRPPAWVHGGAMRSEPTLFAGKDFVSPQAGKDCAADVYRQAKIADPRREIDAVE
                     MYVPFSWYEPMWLENLGFAAEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGLAGEHQVEGARKALGHAYGGGSQFFSMWLVGAEPPTG"
     gene            complement(12721..13782)
                     /db_xref="GeneID:96289066"
                     /locus_tag="IE233_RS05085"
                     /old_locus_tag="GCM10010326_10570"
     CDS             complement(12721..13782)
                     /codon_start=1
                     /db_xref="GeneID:96289066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530287.1"
                     /locus_tag="IE233_RS05085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10570"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_161244554.1"
                     /transl_table=11
                     /translation="MAPTPAARDVAIVAFAQSDHRRRTDELSEVELLMPVLHQVLDATG
                     LKTSDIGFTCSGSSDYLAGRAFSFTMALDGVGAWPPISESHVEMDGAWALYEAWVKILT
                     GEADTALVYGYGKSSPGEVRDVLTRQLDPYYVAPLWPDSVALAALQAQALIDAGETDEP
                     ALAAVAARSREAASANAHAQVRGSRPQGDYVVHPLRTGDCPPIGDGAAAVILAAGDRAR
                     ELCARPAWIRGMDHRIEAHGLGVRDLTDSPSTRLAGERAGAFERPVDTAELHAPFTSQE
                     VVLRKALRLGDDVTVNPSGGALAANPVMAAGLVRLGEAAARIHRGESDRALAHATSGPC
                     LQQNLVAVLEGES"
     gene            complement(13782..14771)
                     /db_xref="GeneID:96289067"
                     /locus_tag="IE233_RS05090"
                     /old_locus_tag="GCM10010326_10580"
     CDS             complement(13782..14771)
                     /codon_start=1
                     /db_xref="GeneID:96289067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003902.1"
                     /locus_tag="IE233_RS05090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10580"
                     /product="Zn-ribbon domain-containing OB-fold protein"
                     /protein_id="WP_189765088.1"
                     /transl_table=11
                     /translation="MAGSAGPEVLRAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRT
                     GDGRVLVPPVEYDPVTAEEIRDLVEVGATGTVTTWAWNPAPRRDQPLDRPFAWVLVQLD
                     GADTALLHALDAPGPEAVHSGMRVRVRWAAERTGAITDIACFEPGEPGETDEPGGTREA
                     GGEPAAHSGRFDDPVTGIVAAARLDYTYSPGRAQSAYINGLSARRTVGERCPSCRKVYV
                     PPRGACPTCGVATEERVEVGPAGTVTTYCIVNIKAKNLDIEVPYVYAHIALDGAGLALH
                     GRIGGIPYDQVRMGLRVEPVWSEGGRYPDHYRPTGEPDADYETYKELI"
     gene            complement(15092..15892)
                     /db_xref="GeneID:96289068"
                     /locus_tag="IE233_RS05095"
                     /old_locus_tag="GCM10010326_10590"
     CDS             complement(15092..15892)
                     /NRPS_PKS="Domain: ECH (9-258). E-value: 3e-52. Score:
                     169.3. Matches aSDomain:
                     nrpspksdomains_IE233_RS05095_ECH.1"
                     /codon_start=1
                     /db_xref="GeneID:96289068"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069072.1"
                     /locus_tag="IE233_RS05095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10590"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_190026314.1"
                     /transl_table=11
                     /translation="MGGTEHLTTHREGATLVLTLNRPEAKNALSLPLLVGLYDGWLEAD
                     ADDSVRSVVLTGAGGDFCAGMDLKALAGQGMAGDQYRDRLKADPDLHWKAMLRHHRPRK
                     PVIAAVEGYCVAGGTEILQGTDIRVAGAGATFGLFEVKRGLFPIGGSTVRLQRQIPRTH
                     ALEMLLTGRPYGAQEAARIGLIGRVVPDGTALDAALEIAEQINACGPLAVEAVKASVYD
                     TASMSEADGLAAELERGWPVFATADAKEGALAFAEKRPAVYRRA"
     aSDomain        complement(15119..15865)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS05095_ECH.1"
                     /evalue="3.00E-52"
                     /label="IE233_RS05095_ECH.1"
                     /locus_tag="IE233_RS05095"
                     /protein_end="258"
                     /protein_start="9"
                     /score="169.3"
                     /tool="antismash"
                     /translation="HREGATLVLTLNRPEAKNALSLPLLVGLYDGWLEADADDSVRSVV
                     LTGAGGDFCAGMDLKALAGQGMAGDQYRDRLKADPDLHWKAMLRHHRPRKPVIAAVEGY
                     CVAGGTEILQGTDIRVAGAGATFGLFEVKRGLFPIGGSTVRLQRQIPRTHALEMLLTGR
                     PYGAQEAARIGLIGRVVPDGTALDAALEIAEQINACGPLAVEAVKASVYDTASMSEADG
                     LAAELERGWPVFATADAKEGALAFAEK"
     misc_feature    15947..15962
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    15952..15966
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.63"
                     /tool="antismash"
     gene            16060..17682
                     /db_xref="GeneID:96289069"
                     /locus_tag="IE233_RS05100"
                     /old_locus_tag="GCM10010326_10600"
     CDS             16060..17682
                     /NRPS_PKS="Domain: AMP-binding (8-438). E-value: 9.6e-67.
                     Score: 217.2. Matches aSDomain:
                     nrpspksdomains_IE233_RS05100_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:96289069"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003900.1"
                     /locus_tag="IE233_RS05100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10600"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_190026315.1"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-69, bitscore:
                     230.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDVVPDREALVYIDHPGTGAERRLTYRQLDEAA
                     NRLAHHLIDAGLKPGEHLGLHLYNGIEYLQTVLAALKARLVPVNVNYRYVEEELVYLYR
                     DADLAALVFDAEFTERVAGALPRTEKLRHLVRVGAAPEGAPALVATAFADAEARGSASR
                     GFAARSADDQFIIYTGGTTGMPKGVMWRQEDLFFAGLFGGEPAGEPVKRPEELAERVAK
                     SGSGLTFFPAPPLMHGTSTLTSFVAFNYGQRVVIHRKYVPAEVLRTIERERVTSVSLVG
                     DAMLRPLVDALHGPLRGTDMSSLFSVSSSGAIMSETVRDQLQALVPNALILNNFGSSES
                     GSNGKATDDSGPEKGFRLEVNERTQVVDPVSYEPVAVGEVGRLAQRGHVPLGYYNDPAK
                     TAETFFQKGAERWVLLGDMATVDEDGIVTVLGRGSQCINTGGEKVYPEEVEQALKAHPD
                     VYDALVAGVPDAKWGSHVAAVVQVRAGTAAPTLEGIQTHCRTRLAGYKVPRQLVIAPSI
                     QRSPSGKADYRWARSVAAEADGT"
     aSDomain        16084..17373
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS05100_AMP-binding.1"
                     /evalue="9.60E-67"
                     /label="IE233_RS05100_AMP-binding.1"
                     /locus_tag="IE233_RS05100"
                     /protein_end="438"
                     /protein_start="8"
                     /score="217.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDVVPDREALVYIDHPGTGAERRLTYRQLDEAANRLAHHLI
                     DAGLKPGEHLGLHLYNGIEYLQTVLAALKARLVPVNVNYRYVEEELVYLYRDADLAALV
                     FDAEFTERVAGALPRTEKLRHLVRVGAAPEGAPALVATAFADAEARGSASRGFAARSAD
                     DQFIIYTGGTTGMPKGVMWRQEDLFFAGLFGGEPAGEPVKRPEELAERVAKSGSGLTFF
                     PAPPLMHGTSTLTSFVAFNYGQRVVIHRKYVPAEVLRTIERERVTSVSLVGDAMLRPLV
                     DALHGPLRGTDMSSLFSVSSSGAIMSETVRDQLQALVPNALILNNFGSSESGSNGKATD
                     DSGPEKGFRLEVNERTQVVDPVSYEPVAVGEVGRLAQRGHVPLGYYNDPAKTAETFFQK
                     GAERWVLLGDMATVDEDGIVTVLGRGSQCIN"
     CDS_motif       16579..16629
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS05100_0001"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="IE233_RS05100"
                     /protein_end="190"
                     /protein_start="173"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVMW"
     CDS_motif       17191..17271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS05100_0002"
                     /evalue="5.50E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="IE233_RS05100"
                     /protein_end="404"
                     /protein_start="377"
                     /score="15.6"
                     /tool="antismash"
                     /translation="GEVGRLAQRGHVPLGYYNDPAKTAETF"
     gene            complement(<17727..18857)
                     /db_xref="GeneID:96295866"
                     /locus_tag="IE233_RS39815"
                     /pseudo=""
     CDS             complement(<17727..18857)
                     /codon_start=1
                     /db_xref="GeneID:96295866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524511.1"
                     /locus_tag="IE233_RS39815"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPKFTTYDGTRIAYHLRGDGPPLICLPGGPMGASAYLGDLGGLTA
                     HRRLVLPDPPGHGGLGGAGRPGVLPLRPSGGRCGDAARPPRTRPPRSARPLRLREPRAP
                     VRRPPPRPGPLADPGGARRPRRGHRGDGGRLAGGRRPAGGRALVRGGAGGLRATVGEGG
                     LLGRGP"
     misc_feature    complement(19068..19082)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.2"
                     /tool="antismash"
     misc_feature    19069..19083
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 24.07"
                     /tool="antismash"
     gene            19082..20374
                     /db_xref="GeneID:96289070"
                     /gene="paaK"
                     /locus_tag="IE233_RS05115"
                     /old_locus_tag="GCM10010326_10630"
     CDS             19082..20374
                     /EC_number="6.2.1.30"
                     /GO_function="GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (71-331). E-value: 3.7e-23.
                     Score: 73.7. Matches aSDomain:
                     nrpspksdomains_IE233_RS05115_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:96289070"
                     /gene="paaK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962681.1"
                     /locus_tag="IE233_RS05115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_10630"
                     /product="phenylacetate--CoA ligase PaaK"
                     /protein_id="WP_161249844.1"
                     /sec_met_domain="AMP-binding (E-value: 9.5e-27, bitscore:
                     89.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPELDAGERLSRPELDALQLDRLRASLRHAYDHVGFYREAFDKA
                     GVRPEDCVSLADLARFPFTAKSDLRDHYPFGMFAVPETDIRRIHASSGTTGRPTVVGYT
                     QRDLDTWADVVARSIRAAGGRPGHKVHVAYGYGLFTGGLGAHYGAERLGCTVIPASGGM
                     TARQVQLIQDFRPEIIMVTPSYMLTLLDEFERQGVDPRTTSLKVGIFGAEPWTQEMRTE
                     IEERFAIDAVDIYGLSEVMGPGVAQECVETKDGLHIWEDHFYPEVVDPLTGAVLPEGER
                     GELVFTSLTKEAMPVIRYRTRDLTRLLPGTARVFRRMEKVTGRSDDLVILRGVNLFPTQ
                     IEEIVLRTPGLAPHFQLRLTRQGRLDALTVRVEARADTTAERREDAARSIVAAVKDGIG
                     VSVAVEIVDPETIERSVGKFKRIVDLREPRD"
     aSDomain        19295..20074
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE233_RS05115_AMP-binding.1"
                     /evalue="3.70E-23"
                     /label="IE233_RS05115_AMP-binding.1"
                     /locus_tag="IE233_RS05115"
                     /protein_end="331"
                     /protein_start="71"
                     /score="73.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HYPFGMFAVPETDIRRIHASSGTTGRPTVVGYTQRDLDTWADVVA
                     RSIRAAGGRPGHKVHVAYGYGLFTGGLGAHYGAERLGCTVIPASGGMTARQVQLIQDFR
                     PEIIMVTPSYMLTLLDEFERQGVDPRTTSLKVGIFGAEPWTQEMRTEIEERFAIDAVDI
                     YGLSEVMGPGVAQECVETKDGLHIWEDHFYPEVVDPLTGAVLPEGERGELVFTSLTKEA
                     MPVIRYRTRDLTRLLPGTARVFRRMEKVTGRSDDLVIL"
     CDS_motif       20045..20107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE233_RS05115_0001"
                     /evalue="1.00E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="IE233_RS05115"
                     /protein_end="342"
                     /protein_start="321"
                     /score="12.0"
                     /tool="antismash"
                     /translation="TGRSDDLVILRGVNLFPTQIE"
ORIGIN
        1 cgtcccatct gttcgcggac cgtcccgctc cccaaccgcc cgagcggggc acggtcgacg
       61 cactgatcac gcagacccgc cgcctgcgcg gcggcgtgga cgcggtgcgc cgcgacgcgc
      121 tcgtggacga ggacgacgcc caggtccgct ggcagcgcgc cctgtgcgac ctggcggtcc
      181 atcaactcga cgacctgggc tcgcacttgg accaactgcg cgacggcctg accgccgagg
      241 aggaggacgc ggcggcgctc gccgtggaga gcgccttcgg tgagggaccg gaggccgcca
      301 ccctgctcac ccgggtcggc agcgccgagt gggacctgct gacggacgcg gtgagctggt
      361 ccgaggagct gttccagatc ttcggccgcg ccgccgggag cggtggcatg tcgctcgacg
      421 aactgcccgc cgtggtggtc gaggacgacc aggccctgct caccacgatg gtgaccggcg
      481 ccctggtgga cggcaggccg atcgacgggg agttccggat cgtacggccc gacggccagg
      541 tccgtacgct ccacatgatg ggcgagcccg tgctcgacgc cgacggctgc accgcttcga
      601 tgtgggccgt cctgcgcgat gtgagtgagc tgcgacgcag ccagcgggcc gtgcgggaga
      661 gccgcgactg ccttcagcgc cggcgccaca tcgcccagac cgagcgccgg ctcgcggtcg
      721 agttgcagga ggccgtgctg ccaccgtggc gcggctccct gcgactcccg cagggcggcc
      781 ccgccgcgct cgacatcgcc gcgcactatc tgccgtcctc cgccggcgcc ctgatcggcg
      841 gcgactggta cgacgcgctc gaactccccg acggcgcctc gttattgacc gtcggcgacc
      901 tcaccggcca cggcgtgacc gcgaccggcg ccatggcgat gctcctcggc gccctgcgcg
      961 gcatggccgt cgcgggcatc ggcccgggcc ccctgatggg ccacctcaac cagcttctgg
     1021 aacagaccgt gcagcccgcc ctgggcagcg cggtctgctg ccgttacgag cccgccgggc
     1081 gcaggctcat ctggtcccag gccggccacc ccgccccgct gctcttccgc gacgggacgg
     1141 gacgcgccct cagcgcaccg gacggggtgc tgctcggcgc cacccacggg gccgcctacg
     1201 gtcaggccga ggtcaccctg cacccgggcg acctgctcgt gctcggcacc ggcgggctga
     1261 cccggcacgg tacgtccgag cacggcgagc agcgccggct gctcgcactc gccccgctct
     1321 tcgacggcgg ccgtagcgcc caggactgcg tacggatgat cgtcgaggag ttcggcgagc
     1381 acgagcgtgc cgacgacgcc tgtgtgctgg tggcccgaat cgggtcctga cgcacaggcc
     1441 tcctgaccca caggcggccg tgaacggccc agcaccgggg ggttgtacgt ttcgggcgta
     1501 caaccccctt ctagatgtcc gccacccggc tccgcttcaa cggggcctgg ggaagggcct
     1561 gttggatctc ctcccggagg tcctggatct ttccgtggcc cgcgtactgg ttggtgagcc
     1621 ggtacatctc gcgcagccgg tcccaggtgc ggtgcgagga ggtctccccc atcgacacca
     1681 gggccagccg ggcgtagcgg tccgcctgtt ccgggtcgtc ggcgatgaag caggccgacg
     1741 cgagcgagat gtagtcgaag atcttcgagc gctgacggcc gcccacccgc agttcgagcg
     1801 cctgcttggc gtggtgctgc gcgatggtgg ccgcggccgg atcgtgctcg gcgagcgtgc
     1861 ggaaggccag ggcctccatg ccgtgcagat ccgcctcgtc gaacatctgc atccaactgg
     1921 gcggcggtac atcgcccttg tcggagacga agagctcctc cgcctcaccg agggtgcggc
     1981 gcatcgcctg cccgcgcccc atggacgcct gggcccatgc ctcgatggtg tgcagcatcg
     2041 cccgggtgcg cggcagggtc tcctcgcccg agccggactt ggcgagcttc atcagatcga
     2101 gtgcttcgcc cgggcggccc aggtggacca tctggcgggc ggcccgcgag agggcctcgc
     2161 cggcacgcgg gcggtcgccg ccctcgcggg ccgcgtgggc ggcgatgacg aagtacttct
     2221 gcgcggtggg ttccagaccg atgtcgtgcg acatccagcc cgccaggacg gcgaggttgg
     2281 cggcaacgcc ccacaggcgg cgctggagat ggtcggggtg gcggtaggcg agcatgccgc
     2341 ccacctcgtt gagctggccc accaccgcct tgcgctggag tccgccaccc cgggaggcgt
     2401 cccaggcgcg gaacacttcg accgagcgct ccagcgcgtc gatctcctgc gacccgatgg
     2461 gagcggcctc gtagcggtcg aacccggcgg ggtcggcgtg cagggggtcg tggaggcggg
     2521 gggcgtcggc cgagagtacg gggtcggtgt gcagccagtc gtgcatggcg ctgctgagta
     2581 ctgagccggt ggcgagcgcg gcgcccgcgc ccaccagacc gcgtcggttg agcatgaggt
     2641 ccattcccgt gaattcggtg aggaccgctg ccgtccgttc gggcgcccac ggaaggccgt
     2701 ccggattctt gatgttcctg acgtcgttcc gctttccagc gcgcccgtgc cggtcgaacc
     2761 cgaggtcctc gatggtcacg acacggccga gccgctcggt gaacagcgcc gccagcaccc
     2821 tgggcaccgg atcgcgcggg gtctccccca tgtcgatcca acgcctcacc cgtgaggtgt
     2881 cggtggccag ttgggggtgg cccatggccg ccgcctgccg gttcaccatt ctcgcgagtt
     2941 cgcccttgga ccatccggcg aggccgaaca ggtcgttcag acgggtgttg ggttgtccgc
     3001 tcacgtcaag cccccaggtt ctcggctgag ttgacagtaa tcccctgtca gatgcggcgc
     3061 gactattcgc cagggttcgc cagggcacgc cagatggtgt gccacccgcg gccgggtgtc
     3121 aggtaagaga gcgccacccc gacccggggg ccggacctca ttccccaggg tgcggctcgg
     3181 ccaccgggac gggtagcgca cgcaacttgt cggcacacga agggatctgt cacccccatg
     3241 tacacagcat cgtcctccgt gtccacgccg ccccggccgc accgtcccct gggagcgggt
     3301 ggcggaccgt acctcgaccc cacccacgcc ggctcggcgt acggcgcggg ccgcatgccg
     3361 cgccggccgg gggcggcccc gcagccgctc agcggaagaa tcgacctctc cggcccccag
     3421 ggcgcccagc tgcgcatcgc gatcgcctcg gtgcagcgga tctgtccgga gttcaacccg
     3481 gtgcaggtgc tgcggcacag cggacgctcc gtgctcatcg tcgggacgac aggacgcacg
     3541 acggccgtcg ccaagtgttt actggaccat tcgcccgcct gggccgagcg cttccggcac
     3601 gaaatagctg catatcgcgc gttcgtccgg caccgcccac cggtgcgggt gccgcggctg
     3661 atcgccgccg atcccgacaa ctgcaccctg gtgatcgagc ggatgcccgg ccgggcggcg
     3721 gccctgaccc gacacccggt cgaggctccc ccacgcgcgg acgtgagggc cgccctcggg
     3781 gcgatcgggc gcgtcaacgc ctggcggccg ccggccgaga tgttcggcag gcccctggac
     3841 tacgcgcccc ggatcgcgcg ctaccacgag ctcggcctct tcaccgaccg ggatctgagc
     3901 gaccttcaga aactgatcca cggtctcgcc ctgtcgggcc gggtcgactg gcagttctcg
     3961 cacggtgacg cgctcctgtc caacatcctc ctttcaccgg ccggtccggt cctggtcgac
     4021 tgggagcacg cgggctggta cctgcccggg tacgacctgg cgacgctgtg ggcggtcctg
     4081 ggcgacgcgc ccgtggagcg acggcagatc gcctcggccg cccaggctgc gggccccgcg
     4141 gcgcgggacg cgttcctggt gaacctgatg ctcgtactga cccgggagat ccggacgtac
     4201 gagacggcgg tgcagcgcac catgcgggat gcgacgccgt cgagcccggt gcagaacgcc
     4261 cctggcgtgc tgtccgccgg ggagcagcag cgactgctgc tgcgcaggct gcacgacgac
     4321 tgcgcgctgg cgcggcgggc ggtgcgggcg gcggtcggca cgcgctgacg gccgggcgag
     4381 gggggaagcg ggccgcgcgc ccagtgccga cacactgggc gcgcggcccg ctgccatacc
     4441 ctcggccggg acctggccgg gcctagcgga cgcgtacgac gtcgacgtcg gaggccttca
     4501 cgaaggcgat ccggtggccg atctgcaccg tgacgtagcg ggtgctgccg gggaagtacg
     4561 tgtggtcgta gggataggac gagtcgatgg tgggggcgta gtagtagccg gtcggcgtcg
     4621 gctcaccacc ggggtaggac tgcccggcct tgatggtgta ggcgagcggg gtgctcaccc
     4681 ggggcgcggt gaagtccgcg gggtagtcgc cggccgccgg gtaggcggtg ccgtagaccg
     4741 ggacgtcggt ccggccccgc ttggggcgta cgacgtagcc ggcggtcgcg gtggcggtgc
     4801 gggtgtgggc ggggctctgg aaccaggcct cctgtccgta ccaccagatc gcggtccagc
     4861 ccggtttccg ttcggcgacc acggcctgct gggtggcgct gatcttgctg ccccagtcgc
     4921 ccgcgcagtt ggtcccgctc tggcccgggg ggtggaggcc ggggtcggcg aacagcggtg
     4981 ccgtggtgga gggttgggtg tacagcggga ccgcgctcga cggctgggcg ggcaggtcga
     5041 tgttcttctc gcagtcgcgg aaggcctgga cgttctgctt gaacaccggg ttgacggtga
     5101 ccagttgacc gccggggcgg ccggtctgct cggtggggcg gccgagcagg cccatgaagt
     5161 agttccagtc ccagtacggc cccgggtccc agtgcatggc ggcggtgccg ccggccgtgg
     5221 tgggcggcac ggtgtcgtgt ccgaggatgt gctgacggtc cagcgggatg tcgtacttgt
     5281 ccgcgaggta gcgcaccagg gccgcggtcg agcggtacat cgcgggggtg aaccaggtgg
     5341 cgccttcggt ggcgtagccc tcctgctcga tcccgatgga gtcggagttg atgtaccagt
     5401 tgccggcctg ccaggcgacg tccttggtct tgaccatctg ggtcacgtga ccgtcgccgg
     5461 accgcacgac atagtgcgcg gaggcggcac gtgtcgggtc ctggaagatc ttcagggtgg
     5521 tcgcgtacgt ctcctcggtg tcgtgcagga cgatgtactt gatcctgttc gtgttcggcc
     5581 ggtcggagac gtcgtagttg ccgtacgcct ccttgttggc ggggtcgccg gtctgctggt
     5641 aggcggccgg aacccagtcg cacttcagga cgcgggggca ttcggtgccg gagcccgccg
     5701 cgctcgccgc ggtggcgggg gccagggcca ggcccagggc tccggccgtc gccgtagcga
     5761 gcgcgagtct gatcctctgc ttggacgtca tggacaaccc ttcttgccgg aaggtgcggg
     5821 gctctctcgc cgcagccgcg cgtgggtgcg cgcgggacac agtgcgacct ggcatgacgg
     5881 ctcgtcaagt acccctcggg cgcgccgact tgtatcagtg gacgagacca gtggcggcgg
     5941 ccctgacctg ccggtgtcgc cacgggctca acggcagtac gggcaggccg acttcagggc
     6001 cggcggcgtt cgggagccgc caccggcgcc gggcgctccc ggccccggac atgaagcggc
     6061 ccggcacctc gggcggaagg tgccgggctg tcggccggtg cgcgggcgcg ggctcagctc
     6121 tgctggaaga gctccgcggg cagcggcttc aggagggcgt acaggtcgtc cgtgatcggc
     6181 cggtcccagc tggcgatcgt gacgaggacg tcgtcgctgc ggtcgaactg gacgcaggag
     6241 atgcggcttt cggagagctt gagccggcgc acgatgagga ggttgtcgcc ctgcatcacc
     6301 ggcatgtcct cggtgccgac gacctcgatc ggctcgtcgt tctccagggc caccaggagc
     6361 tgggcgacct cgaacggaac ctgcccctcg gccatctcgc gggccgggga gcccgccgga
     6421 agattgccga tgatcatcgc ggggccgcgg ccgccgaaca ggtcgtagcg caggaagaca
     6481 ccctggcagc tgccgtcggg ggcgggcagc agaccggcgc ccaggttgcc gggccagtca
     6541 cccgggtcca tggccaggac atcgaagtcc gggcccgcgg gagtggcggc gctgcggcgg
     6601 cggaggaagg acatgccgtc aatggtacgt gcccccggcg ctccggcgga gccgggcccg
     6661 aagcgctggg cgggtcgaca cccggcgtcc cgcggggccg tggggcgtgc gggtggccgt
     6721 gctccgcccc gggggacggg gcggcgtgcc acggccccgg ctcccccgcc gatgggcgct
     6781 cgggggccgg ggccgtgccg gggtgcttca gaggccgggc actcctcgga ctccggagcc
     6841 gcgggactgg tggggcagca gcccggctag tccgtcgcgg ttggtgccga gcttgcggaa
     6901 ggcaccggag agcaggagtt ccacggtgcg ctccttggtg ccgagctcct cggcgatgcg
     6961 ccggttctcc cagccctggg cggcccgctc ggccacggcc ttctcctggg aggtcagcga
     7021 gtccgagtcg acggcccgca gctggagcgg gcggagcccg gaggcggcga gttcctcacg
     7081 ggcccgggcg gccagggcgt cggccccgca cagggcggcg ctctccaggc cgcgcatgag
     7141 caggtcggcc gcgtcctgcg gcagcccggc gcggctgagc atcgcgccgt ggtcgatcag
     7201 tgcctgggcc agctcgtagg cggccggaga cttttcgagc tgccggaccg cctcggacat
     7261 cagggccagg ctgtcggcgc cggaggtcac cttggccgcc gcgtgcaggg cgcggccgac
     7321 cgcacccggg gtgccgaagc ggcgggcgat ctcgacgccc tcctgcgcga tcgcggcggc
     7381 ctcgacggga tcggtgtggg cgatcgtctg ggccaggagc gggcgccacg ggcaccacat
     7441 cgggttgcgc atgccgcgcg gctccagcct gcggcccacc gcgcgcagcc gtgcctcggc
     7501 gtccgtgcgc agtccccggg cgatgaggag ctcgctgtag acggtctcgg agtccgggta
     7561 gacgacggcg ttcggaacga cctggccgta gttgtaggcg tcggagagtt cctgcgcgtc
     7621 ctggacccgg ccgcgggcga gcaggatctc gatgaggatg ccgagcgcga accactgcgc
     7681 gggcacctga tggcccacgc ggtcggcgat ccgcagcccg ctgtgcacca ggtcctcggc
     7741 ctcggagagc cggccgcggt ggaacttgat gtagccgagc agcgtcaggc cgaaggacag
     7801 gtgcgcgccg cgccagccct tgcgttcgca gtcggcgatg ccctgggtga acagctcgtc
     7861 ggcgcggccg ggctggtcgc agtacatgaa ggtgagcgcg accaggaccg ggacctcgaa
     7921 gccccagttg tcgtcggtcc aggagagccc gccctccagg gcctcctcgg cgtagcgcag
     7981 tgccgtctcg gcgggttcgc cgcgcaccat cgcgtcccag gcgcgcaggc cgaggatgta
     8041 gcgctcggcc ttgccgcgcc cggtgatgtg ctcggcgagc cgggccaggc tgcgcgagcg
     8101 cgccggggag tcctcctcgt cggcgcggaa ggcgttccac tggaagctct cggcctgcat
     8161 gcgcagccgt gtacgggcgc tgccggagtt cttggcctcg gcgcccacga tggcggcggc
     8221 ctcgcccatc cggtccgtgt gggccagcgc ctgggcgagc cggtaggtga cggcttcgcg
     8281 cagttccggg gcgagttcgg gttcttcgag ggccgccttg aggtggttga cggtggtggc
     8341 gggctcgttc aggagcgccg agcagccgag ttcgaagagg acttcggcgc gctcctccag
     8401 ggcgggtggt tcgcgcaggg cgcgggccag acagcgccgg gccgcgtccg gggcaccggc
     8461 ccgcaggtag tcgcgggcgg cggcgcgcag ctggcgcacc gcccaccggt cgttctcggg
     8521 gtgcatctcc aggatgtgcc gggccgcgga ggtggcgccg agtccggcct cgctgacggc
     8581 gaaggcggcc tggccgtgca tcgcgacgcg catggcggac gggatggcgc ggtagacggc
     8641 ggtgccgacc agcgggtgga agaagtcgag ccggtccgga tggtcgtcgc tctgctcggc
     8701 caggatgcgg gcgtcgcgca gcttgccgac cgcgtcggcc atctcctcca cgccgagtcc
     8761 cgcgactccg gcggccatct cccggcgtgc gtcggtgccg agcacggcga cggcccaggt
     8821 gagccggaac gcggaggggc cgagccgctc caggcgttcg atgaggccgt tgccgcgtac
     8881 ggcggaggcc agttcgcgca gttcggtggc gttggcgtac tgcggtttga tgccgcggtc
     8941 gcggattctc gcgacgagct cgacggcttc gtaggggttg cccgcggtca gggcccagca
     9001 ttcgcgtgcg aacagttcgt cgccgccttc gccgagcacg tcgcgcacca ggtcgctgac
     9061 ggcggccggg gtgaacggcg agaggtccag cggacgcgag ccgtgccggg tggcgagccg
     9121 gcggaactcg gccgcgtggc gcggaagttc ctcgggccgg taggcgacga cgatgagcag
     9181 cggcaggtcg gccgcgcgca gcgcgaacga ggtgagccag gccagggtct cctcgtccgc
     9241 ccagtgggcg tcgtccacca cgagcaccac gggtgcgtac tggacggcga agcgggtgac
     9301 gagccagtcg agaccgtccc gcacgccttg cggatcgggt gccaccccgc tctttccggc
     9361 gaccaggccg accgccggtg cgacgatgtc gtaccaactc cccagtatct tgcggtgttc
     9421 ttcctcgctc gtcgcggcga ggaccggctg cacgagctgg cgcacgacgt ggaacgcgac
     9481 gccttcctcc tgctcgctgc cacgtgcggc cagcagggtg cagccgcggg ccgcggcttt
     9541 tcgccggacc tcggccacca gggtggtctt gcccaggccg gccgatccgg cgatggcgag
     9601 cagtccgccg ttgggcgcgc tcccctcacc tgcccggccg cacagatcgt ccaacatgct
     9661 gtcgaacagc agcagttctt cgtcgcgctc aaagagcatc cggcgcggca cgccgccccg
     9721 gcccttcgtc tccgccgcag cggtcccctt ctggcagtag caccgagcct acgccccgga
     9781 tacgtaccgt gacatgaata cccgacctcc gtctcctcct tgactgttta agttggctga
     9841 atccatgggt ggttgacatc caaatgtccc ggtggggcgc caggaggggc ctcgtacgcc
     9901 ccccatgcgc tgtcggactc cgccaccgcg cgactggctt cgggaggccc tcaccttgat
     9961 gattgaacta cgtacggagc agtgaaggag gcggtgccgc atgggcagca ctggcagggt
    10021 ccggtcggcc aggatgcgga ccggtctcgt cgacattccc tttccggccc gcaggcatcc
    10081 ccgggacgcc ctggcccggc gccacacgct cgactggctc tacgagttcg gcatgctggc
    10141 cggggagcag gccacggccg agtacgacgc gatgggcctg gagcgcctga tggcgtactt
    10201 ctatccggac gcctcggacg cgcatctcgc actggcgacc gacctcaacg cctggttctt
    10261 cgtcttcgac gaccagttcg acggtccgct cgggaagcgc cccgacgtgg tgctgcgcca
    10321 gatcgacacg gtgttgcgca ccatgagtga cgaggctccg gtggcgggcg agacgacgaa
    10381 ccggctggcc gaaagttttc gtgatctttg gcaacgggtc accgcgggca cgccgttact
    10441 gtggcaggac cgcttccggg cgcactggcg cgagtatctg acggcgtatc actgggaggc
    10501 gctgaaccgc acccgcaacg gcaccctgtc gctgcccggc ttcctgcgcg gccgccggga
    10561 ctccataggc gtgcagccct gtcttgacct ggtggagcgc tgcggcggct acacgctgcc
    10621 cagggagctc cacggcgggg tgccgctggc cgagatgcgg gagatcaccg ccgatgtggt
    10681 catcttcgtc aacgacatgg tgtccgtgga caaggagctg gcggcgggcg acgtcaacaa
    10741 cagcgtgatc atcctgatgc ggcaggaggc ctgcaccgtc gagcaggctc tgcgccgggt
    10801 ggccgtcatg gccaactccc gcatcgcgcg cttccaggag ctgaccgtcg agctcgccgc
    10861 ccagctcgac aagaccgcgc ttcccgagca ggtgcgggcg aacgtggacg actacgtcga
    10921 cggcatgcgt ggcctcatga gcggcaacct ggcgtggtcc ctggagaccg cgcggtacgg
    10981 cgaggcgggc atcgccgccg tcagcgaggg ccgccagcgg ccctgggcgc ggctcttccc
    11041 cgagcaagcc acggaggagc gggaaggcgc ctagcgctca accggcatat gagaaggggg
    11101 tgttgaggag gcaaccggcc tcctcaacac cccctcctgg cacgaaggcg caccggcggg
    11161 accggcggcc gcgggcgcgg acgctaggtg aggtcgaact cgccgtcgcg cgcgttgatc
    11221 acgaaggccc gccattccgc ggggctgaag atcagcgacg ggctgccggg gctgccgctg
    11281 ttgcgcatgg cgatgaaacc ctcgacgaag gcgatctgga cgtcccccgc cccctgactg
    11341 ctcgactgcc actcggcctg gctgaggtcg agctccggct tgtcccagcc ggaacgggtg
    11401 tgacccgcaa gggtccgcaa ggtgtgctgg gttgtgctgg tgtcagccac gtccgtgctc
    11461 ctccccggtt ctgtcgttcg gggccaccct agcgatcgtc cgcggggacg gacaggccac
    11521 ggaaggagta cccgggcccg cccgccgcga acgggactca gccggtgggc ggttcggcgc
    11581 cgacgagcca catcgagaag aactgggagc cgccgccgta ggcatggccg agggccttgc
    11641 gggccccttc cacctggtgt tccccggcca ggccacgcac ctggagggcc gcctcggcga
    11701 agcggatcat gccggaggct ccgatgggat tggtggacag cacgccgccc gacgggttca
    11761 cggggaggtc gccgtcgagt tccgtgacgc cggcctcggt gagcttccac ccctcgccct
    11821 cggcggcgaa gcccaggttc tccagccaca tcggctcgta ccaggagaac ggcacgtaca
    11881 tctcgaccgc gtcgatctcg cgccgcgggt cggcgatctt ggcctgccgg tacacgtcgg
    11941 ccgcgcagtc cttgcccgcc tgcggggaga cgaagtcctt gcccgcgaac agggtcggct
    12001 cgctgcgcat cgcgccgccg tgcacccagg cgggcgggcg gggcgaacgg gccgcgcccg
    12061 cacggtcggt gaggatcatc gcgcaggccc cgtcggagga cgggcacgtc tcggagtagc
    12121 ggatcgggtc ccacagcatc ggggaggcct ggaccttctc cagggtgatg tcgtgctcgt
    12181 gcagatgcgc gtacgggttc ttcagggcgt tgcgccggtc cttgtacgcg acgagggagc
    12241 ccaccgtgtc gggggcgccg gtgcgccgca tgtacgcccg gacgtgcggg gcgaagaagc
    12301 ccccggcccc cgcgagcagc ggctgggtga agggcacggg cagggacagg ccccacatgg
    12361 cgttggactc ggactgcttc tcgaaggcga gggtgagcac ggtccggtgc acccgggcgg
    12421 cgacgaggtt ggaggcgacg agggcggtcg agccgccgac ggagcccgcg gtgtgcaccc
    12481 gcagcatcgg cttgccgacc gcgccgagcg cgtcggcgag gtagagctcg ggcatcatga
    12541 cgccttcgaa gaagtcgggc gcctttccga tgacgacggc gtcgatgtcc ggccagccca
    12601 acccggcgtc gtccagggcc cgttgggcgg cctcgcggac gagtcccgct atcgacacgt
    12661 cgtgccgggc ggccacgtgc ttggtctggc cgacgccgac gacggccacg ggttccttgc
    12721 tcatgactcc ccctccagga cggcgaccag gttctgctga aggcaggggc cggacgtggc
    12781 gtgcgcgagg gcccggtcgg actcgccccg gtggatgcgg gcggcggcct cgccgagccg
    12841 tacgaggccg gccgccatca cggggttcgc ggcgagcgcg ccgccggacg ggttgacggt
    12901 gacgtcgtcg ccgagccgca gcgccttgcg caggacgacc tcctgcgagg tgaacggtgc
    12961 gtgcaactcg gcggtgtcca cgggccgttc gaaggcgccg gcccgttcgc cggcgagccg
    13021 ggtggacggc gagtcggtga ggtcgcgcac gcccaggccg tgcgcctcga tgcggtggtc
    13081 catgccgcgg atccaggcgg gccgcgcgca cagctcacgg gcccggtcgc ccgcggcgag
    13141 gatcaccgcg gcggcgccgt ccccgatcgg agggcagtcc ccggtacgca acggatgcac
    13201 cacgtagtcg ccctgcgggc gcgaaccccg cacctgtgca tgggcgttgg cgctcgcggc
    13261 ctcgcggctg cgggccgcga cggcggcgag cgcgggctcg tcggtctccc ccgcgtcgat
    13321 gagggcctgg gcctggaggg cggcgagtgc gaccgagtcg ggccacagcg gcgccacgta
    13381 gtacgggtcg agctggcggg tcaggacgtc gcgcacctcg ccgggagagg acttcccgta
    13441 gccgtagacg agcgcggtgt cggcctcacc ggtgagaatc ttcacccagg cctcgtagag
    13501 cgcccaggcg ccgtccatct ccacatggga ctcggagatc ggcggccagg cgccgacccc
    13561 gtcgagcgcc atggtgaagg agaaggcgcg gcccgcgagg tagtcgcttg agccggagca
    13621 ggtgaagccg atgtcgctgg tcttcaggcc ggtggcgtcc aggacctggt gcagcaccgg
    13681 catgaggagt tcgacctcgg acagctcgtc ggtgcggcgc cggtggtcgc tctgcgcgaa
    13741 cgcgacgatc gccacgtccc gggcggcggg tgtgggcgcc atcagatcag ctccttgtac
    13801 gtctcgtagt cggcgtcggg ttctccggtg ggccggtagt ggtcggggta gcggccgccc
    13861 tcgctccaca ccggctccac ccgcagcccc atccgcacct ggtcgtaggg gatgccgccg
    13921 atccgcccgt gcagggcgag cccggcgccg tcgagcgcga tgtgggcgta gacgtagggc
    13981 acttcgatgt cgaggttctt cgccttgatg ttcacgatgc agtacgtggt gacggtcccg
    14041 gcgggcccga cctcgacccg ctcctcggtg gcgaccccgc aggtggggca ggcgccgcgc
    14101 ggcggcacgt acaccttgcg gcaggagggg cagcgctcgc cgacggtccg gcgggcggag
    14161 aggccgttga tgtacgcgga ctgggcgcgc cccgggctgt aggtgtagtc gagccgcgcg
    14221 gccgcaacga tcccggtgac gggatcgtcg aaccggccac tgtgcgcggc gggttcacct
    14281 cccgcctcac gtgttccacc gggctcatcc gtttcaccgg gttcaccggg ttcgaagcag
    14341 gcgatgtcgg tgatggcgcc ggtgcgttcg gcggcccagc ggacacggac gcgcatcccg
    14401 ctgtgcacag cctcggggcc gggcgcgtcc agggcgtgca ggagggcggt gtcggcgccg
    14461 tccagctgga cgagcaccca cgcgaaaggc cggtcgaggg gctggtcgcg gcgcggggcg
    14521 ggattccagg cccaggtggt gacggtgccg gtggcaccga cctcgacgag atcgcggatc
    14581 tcctcggcgg tgacggggtc gtactcgacg ggcggcacga gaacacgccc gtcccccgta
    14641 cgcaccccga gcacggtccg ctcccgcagc cccgtgagga aggcgctctg gaccggcccc
    14701 agggaccggg tgaagggaaa ctcgacgaca agcggcgccc gcaacacctc gggcccagca
    14761 gagccagcca tgatccaact ccttaagtac cgtcaattac cgggccactt ggagcccgtc
    14821 gggcgttcga ggcaccgggc cgctcgcagc cccctccggc tcacggggcc ccgggcgggc
    14881 acccgcattc cgtccggcgt ccgaggctcc gggccacctg cggcctctga cgtacgaggc
    14941 cccgggcggc cacccgcggt ccgccgatcg atgggggctc ccggccacct gcggtccgtc
    15001 cggcgtttcg aggacgagcg gcctctcaag gcgcgagccg ggtccggggc ggagcccccg
    15061 cgcccctctc ccgggggacg ggggcagggg ctcaggcccg ccggtatacg gcgggccgct
    15121 tctcggcgaa cgccagcgcc ccctccttcg catccgccgt ggcgaacacc ggccacccgc
    15181 gttcgagctc ggccgccagc ccgtccgcct cgctcatgga cgccgtgtcg tacacggagg
    15241 ccttgaccgc ctcgacggcg agcggcccgc acgcgttgat ctgctccgcg atctccagcg
    15301 ccgcatcgag cgccgtcccg tccggcacca cccgcccgat cagcccgatc cgggccgcct
    15361 cctgcgcacc gtacggccgc cccgtcagca gcatctccag cgcgtgcgtg cgcggaatct
    15421 gccgctggag gcggacggtc gagcccccga tcgggaagag cccgcgcttc acctcgaaga
    15481 gcccgaacgt cgccccggcc cccgcgaccc ggatgtccgt gccctggagg atctcggtgc
    15541 ccccggccac gcagtacccc tcgacggcgg cgatcacggg cttgcggggc cggtggtggc
    15601 gcagcatcgc cttccagtgc agatcggggt cggccttgag ccggtcccgg tactggtccc
    15661 cggccatgcc ctgccccgcc agggccttga ggtccatgcc ggcgcagaag tcaccgcccg
    15721 cgccggtgag cacgaccgag cggaccgagt cgtccgcgtc ggcctccagc cagccgtcgt
    15781 agagccccac cagcaaggga agcgacagcg cgttcttcgc ctccggccgg ttcagggtga
    15841 gcaccaaggt ggcgccctcg cgatgcgtcg tgaggtgttc cgtaccgccc acagccgtcc
    15901 tcccgtctca agacctagaa caggttgcag taggggcggt gtcagttcaa tagttttctg
    15961 acactcagtc agttttcttc tgtggcaccc cttccctgtt gtgcgcggct ttgttctgat
    16021 gacccccgag ttcagtcggg gccggtgtca ggaggaatgg tggagtacaa ccttgccgac
    16081 ctgttcgagt ccgtcgtcga cgtggtcccg gaccgcgaag cgctcgtgta catcgaccat
    16141 cccggaacgg gtgccgaacg cagactgacg taccgtcagc tggatgaggc ggcgaaccgg
    16201 ctcgcgcacc acctcatcga cgcgggcctg aagcccggtg aacacctggg cctgcacctc
    16261 tacaacggca tcgagtacct gcagaccgtg ctcgccgcgc tcaaggcgcg gctggtgccg
    16321 gtcaacgtca actaccgcta cgtggaagag gagttggtct atctctaccg ggacgccgac
    16381 ctcgcggccc tcgtcttcga cgccgagttc accgagcggg tcgcgggcgc actgccccgc
    16441 acggagaagc tgcggcacct ggtccgggtc ggggccgctc ccgagggggc cccggccctg
    16501 gtcgcgacgg cgttcgccga cgcggaggcc cggggctccg cctcgcgggg cttcgcggcg
    16561 cgttcggcgg acgaccagtt catcatctac acgggcggca ccacggggat gcccaagggg
    16621 gtgatgtggc gtcaggagga cctcttcttc gcggggttgt tcggcggcga accggccggc
    16681 gaaccggtga agcgccccga ggaactggcc gagcgggtcg ccaagagcgg ctcgggcctc
    16741 accttcttcc ccgctccccc gctcatgcac ggcacctcca cactgacctc cttcgtcgcc
    16801 ttcaactacg gccagcgggt ggtcatccac cgcaagtacg tccccgcaga ggtgctccgc
    16861 acgatcgaga gggagcgggt caccagcgtc tccctggtcg gtgacgcgat gctgcggccc
    16921 ctcgtcgacg cgctgcacgg cccgctccgg ggcaccgaca tgtcctcgct gttcagcgtg
    16981 tcctcgtccg gcgcgatcat gtccgagacg gtgcgcgacc agttgcaggc gctggtgccg
    17041 aacgcgctga tcctcaacaa cttcggctcg tccgagtccg gctccaacgg caaggccacg
    17101 gacgactcgg gcccggagaa gggcttccgg ctggaggtca acgagcgtac gcaggtggtc
    17161 gatccggtgt cgtacgagcc ggtcgcggtc ggcgaggtgg ggcggctcgc ccagcgcgga
    17221 cacgtgccgc tgggctacta caacgacccg gcgaagaccg ccgagacctt cttccagaag
    17281 ggtgccgagc ggtgggtgct gctcggcgac atggcgaccg tcgacgagga cggcatcgtc
    17341 acggtgctcg ggcggggctc gcagtgcatc aacaccggcg gcgagaaggt ctacccggag
    17401 gaggtcgagc aggccctcaa ggcgcatccc gatgtgtacg acgcgctggt ggccggggtg
    17461 ccggacgcca agtggggcag ccacgtggcg gcggtggtcc aggttcgcgc cgggacggcc
    17521 gcgccgacgc tcgaagggat acagacccac tgccgcaccc gcctcgccgg ctacaaggtg
    17581 ccccggcagc tggtgatcgc ccccagcatc cagcgctccc ccagcggcaa ggcggactac
    17641 cgctgggcgc gctcggtcgc cgccgaggcc gacggcacct gatcggacgg cagggacggc
    17701 agccgaccgg agccgtgcgt ccggccgatg ccgaactccc cgagggcgga caggatttga
    17761 tcgggccggt cggtgtgcac gaggtggccg gcgccgatgg tgacgaggcg ggcgcccggt
    17821 atccgcgagg ccatccgggc cggcttcttc tggtcgacgt gcccggcccg gccgcccgcg
    17881 acgaccgggg tgggcgtggc gatggcggcg aaccggccgc gccaggccgg gtcgggatca
    17941 cgggcggtgc ggtccggggg ccgcgcgccc gctaggcgag ccggacaccg tcgacgacga
    18001 ccgtgcgcgc ctccgggtcg aggaaggcgg cgacagtacg cacgaaggcc tccgggtcgt
    18061 cgacccacgg ggagtgcccg gcgccccgtt gcacgacgag ctcggcgtcc gggaagaggg
    18121 cggccagttc ggcggcgcgt gtcggggccg gtccgccgtc gtactcgccc gcgatcacca
    18181 ggacgggcgc ggcaagcccc gcgagggcgg cgacggtggc cgccgggtcg aaggcgccgt
    18241 ccgcgtagta ggcgcccgcc agggcctggt cccgcacggc tcgggtgagg gcctcgtgcc
    18301 gctgggccgc cgcgtcccac cgcccgtagg cgaagggcct gatggcgtca aggacctcgc
    18361 cccaagaggc ctccttcgcc cacagtcgct ctaaggccgc ccgcccctcc tcgtaccagg
    18421 gctcgcccgc ccgcagggcg acggccgccc gccagtcgtc ctccgtcacc tcgatgccca
    18481 cggcgcggac gccgggcgcc accagggtca gcgagcggac ccggtcgggg tggcgggcgg
    18541 cgtacaggag cgcgaggttc ccggaggcgg agtgggcgag cagatcgagg cggtcgagtc
    18601 cgaggtggac gcgcagcgtc tccacatcgg ccacctgacg gtcgcagcgg aaggacgccg
    18661 ggtcgtccgg cacctccgag tcccccgtgc cccggggggt cgggcagcac cagccgacgg
    18721 tgcgcggtga gcccgcccag gtccccgagg taggcggagg cgcccatcgg gccgcccggc
    18781 agacagatca gcgggggacc gtcgccgcgc aggtggtagg cgatccgcgt tccgtcgtac
    18841 gtcgtgaact tcggcatgcg gccgatcctc acagccgccc tgcgcgcccg gcaatcccgt
    18901 ttcgcccacg gcgcgatcat gaacggccgc ccccgcccag gcggggcgct ccgacttgtc
    18961 cacaggcctt gacggacccc tcgggctgct gaattactga tcagacacag atcgaccgaa
    19021 tgatcggtcg tccgatttcg tcgccccttc cccggggcgg agcgaggacg ggagcgcacc
    19081 catggcacct gagctggacg cgggcgagcg gctgagccga ccggagctcg atgccctgca
    19141 gctcgaccgg ctgcgtgcct cgctgcgtca cgcctacgac cacgtcgggt tctaccggga
    19201 ggccttcgac aaggccgggg tgcgcccgga ggactgcgtc tcgctcgccg atctggcgcg
    19261 cttccccttc accgccaagt ccgatctccg cgaccactac ccgttcggca tgttcgcggt
    19321 ccccgagacc gacatccggc gcatccacgc ctccagcggc acgacgggcc gcccgaccgt
    19381 cgtcggctac acccagcggg acctggacac ctgggcggac gtggtggccc gctcgatccg
    19441 cgcggcgggc ggcaggccgg gccacaaggt ccatgtggcc tacgggtacg gactgttcac
    19501 cggcggtctc ggcgcgcact acggggccga gcggctcggc tgcacggtga tcccggcctc
    19561 cggcggcatg acggcacgtc aggtgcagct gatccaggac ttccgtccgg agatcatcat
    19621 ggtgaccccg tcctacatgc tcacgctgct cgacgagttc gagcggcagg gcgtcgaccc
    19681 ccgcaccacc tcgctcaagg tgggcatctt cggcgcggag ccgtggacgc aggagatgcg
    19741 caccgagatc gaggagcggt tcgcgatcga cgcggtcgac atctacggcc tgtcggaggt
    19801 catgggcccg ggcgtcgcgc aggagtgcgt ggagaccaag gacgggctgc acatctggga
    19861 ggaccacttc tacccggagg tggtggaccc gctgaccggc gcggtgctgc cggagggcga
    19921 gcgcggcgag ctggtcttca cctcgctcac caaggaggcg atgccggtga tccgctaccg
    19981 gaccagggat ctgacccggc tcctccccgg tacggcgcgg gtgttccggc ggatggagaa
    20041 ggtgaccggg cgcagtgacg acctggtcat cctgcgcggg gtgaacctct tccccaccca
    20101 gatcgaggag atcgtgctgc gcacgcccgg cctcgccccg cacttccagc tgcgcctgac
    20161 ccgccagggc cggctcgacg cgctgacggt acgcgtggag gcccgggcgg acaccaccgc
    20221 ggagcggcgc gaggacgccg cccgctcgat cgtcgcggcg gtcaaggacg ggatcggcgt
    20281 ctccgtggcg gtggagatcg tcgaccccga gaccatcgaa cgctcggtgg gcaagttcaa
    20341 gcgcatcgtg gacctgcggg agccgcgtga ctgacgaccg cggcgggccc ggcccgacat
    20401 gacaggtact caggcgaacc ggtcacgcag ttcgcgcttg aggatcttgc cgctcgcgtt
    20461 gcgcggcagt tcgtccacga acaggacccg cttgggcgcc ttgaagtggg cgagcaactt
    20521 ccttgcatga tcgatgagtt gggcctcggt caccgatccc tgcgtaccct cgcgccgtac
    20581 gacgaacgcg gtgaccgcct cgatccagcg ctcgtcgggc agccccacca cggcggcctc
    20641 ggcgaccgcg ggatgggtgt agagggcgtc ctcgacctgg cgcgaggcga tgaggacgcc
    20701 cccggagttg atgacgtcct tcacccggtc gacgacggtg aagtaccccc cgtcgtcgcg
    20761 caccgcgagg tcacccgagt ggaaccagcc gtcgcggaag gcgtccgcgg tctcggccgg
    20821 cttgtcccag tagccctcgc acaactgcgg tgagcggtac accacttcgc ccgccgtccc
    20881 gtcgggcacc tccttgccgc tctcgtccac gaccttcgcc tcgacgaaca gcacgggccg
    20941 cccgcacgag tcgagccgcc cctcgtgctc ctcgggcccg agcacggtgg ccagcggccc
    21001 gatctcgctc tgtccgaagc agttgtagaa cgcgagcccc ggcagccggg cgcgcagccg
    21061 ctccaggacc ggca
//
