LOCUS       NZ_BMUU01000001        21053 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces xanthochromogenes strain JCM 4594 sequence01, whole
            genome shotgun sequence.
ACCESSION   NZ_BMUU01000001
VERSION     NZ_BMUU01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces xanthochromogenes
  ORGANISM  Streptomyces xanthochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1270804)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 59X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650355.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,827
            CDSs (total)                      :: 7,752
            Genes (coding)                    :: 7,642
            CDSs (with protein)               :: 7,642
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 24 of 110
            Pseudo Genes (incomplete)         :: 94 of 110
            Pseudo Genes (internal stop)      :: 7 of 110
            Pseudo Genes (multiple problems)  :: 12 of 110
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 673309
            Orig. end                         :: 694362
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUU01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(608..622)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    840..854
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.16"
                     /tool="antismash"
     gene            complement(923..1807)
                     /db_xref="GeneID:96288639"
                     /locus_tag="IE233_RS02935"
                     /old_locus_tag="GCM10010326_06160"
     CDS             complement(923..1807)
                     /codon_start=1
                     /db_xref="GeneID:96288639"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676882.1"
                     /locus_tag="IE233_RS02935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06160"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_190026081.1"
                     /transl_table=11
                     /translation="MDDWYVDDRCTNCDVARQFAPELIGETGGKSQILRPPSGAEETRR
                     LHAAVFACPTRSIRPRSGRADRSRDPFPMELDDGLWICGHNSRHTAGANSYLLLRPNGT
                     AMMIDTPRWSAELADRYAASGPVTDVLLTHRDHAAHGRSYADHFGARLWIHEGDLDAAP
                     DADCVIRGIDPVEIAEGVTVHPLPGHTRGSVLYLADDYLADDRYCFSGDSFYWSRATGD
                     LEVADSVTWYSIEEQAVSLARTAERLRFEWVLPGHGDRHRLPADEMSRRLRALTERTRL
                     LEPRPVDFTAVRW"
     gene            complement(2009..3949)
                     /db_xref="GeneID:96288640"
                     /locus_tag="IE233_RS02940"
                     /old_locus_tag="GCM10010326_06170"
     CDS             complement(2009..3949)
                     /codon_start=1
                     /db_xref="GeneID:96288640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970863.1"
                     /locus_tag="IE233_RS02940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06170"
                     /product="hypothetical protein"
                     /protein_id="WP_161254345.1"
                     /transl_table=11
                     /translation="MSAPQRERHPRPAGPVPALGQAEATLVEHYPRLVRLAYLILPPRL
                     GRHRRVLAAHGVVQNALPARPTPIKKGRVPAPRDDRAPALGWIVRRVVGAALSYEHGAA
                     RWRRAVRPALPAVWGLRLTPRIGGADELALEQQLATVPAGVRAAFVLQHLEGYASDTAA
                     ELLTAAGVPDPEAALRAAKALGPQDDGTRAGLLLDSVEFDPCTVQARPTDLLRRRHWRR
                     WGAAAALLVAVMLTVGQSAKDPASPEPTTPSAVGVAMVDPGAVGRAPGTAWQSSSRIDF
                     TVWPARGSLVDDQALLGRALRAWARPGTAVQVSAAPRTGTGPTAAPPQLLYAGRVDDAD
                     VVLLYDGERVVRYAETTGQPAELAFSRADNADVTTAAALVLSRTGSRTRFLLAPWVAES
                     TTRDLLAPDSPARPLHVGDDGVSDAVARPDLTGPCSNWPALQLRSSERIAEKHAFLLTD
                     LGDLSPVHLTYTPPPGGGVPARQPREATSTAALVSWSHTACTLRSAVGGGVRSVNNWVF
                     AEQQLPENAGQAEWLCSRADTWNGPGRAVVRFQPPTTAAREPGTLIADARDTSYCSRFN
                     QHILADAHWSAPSGASYLLAAGSRAVTRITVTGQVRADTTGTTLAVKAPPGQSAEIGAV
                     LSTGRTLGAVH"
     misc_feature    complement(3952..3966)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.42"
                     /tool="antismash"
     gene            4468..4824
                     /db_xref="GeneID:96288641"
                     /locus_tag="IE233_RS02945"
                     /old_locus_tag="GCM10010326_06180"
     CDS             4468..4824
                     /codon_start=1
                     /db_xref="GeneID:96288641"
                     /inference="COORDINATES: protein motif:HMM:NF013098.5"
                     /locus_tag="IE233_RS02945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06180"
                     /product="VOC family protein"
                     /protein_id="WP_161254342.1"
                     /transl_table=11
                     /translation="MRTTHIMANLPVADIATAKSFYRDYLGLSTEEFDLTWVARCTSPD
                     SAASVQLVTHDATAPEDSVISVLTDDVEGAYAEARRLGFEIVHPLTTEPWGHRRFFVRA
                     PDGNVINIGFHGDV"
     gene            5074..5262
                     /db_xref="GeneID:96288642"
                     /locus_tag="IE233_RS02950"
                     /old_locus_tag="GCM10010326_06190"
     CDS             5074..5262
                     /codon_start=1
                     /db_xref="GeneID:96288642"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE233_RS02950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010326_06190"
                     /product="hypothetical protein"
                     /protein_id="WP_161254339.1"
                     /transl_table=11
                     /translation="MYEMHVGTAVTGTRRVWHVVAHDQRATLCGQPLEPVEDTQTDHHC
                     LPCMSAFQRLMQAVEPA"
     gene            complement(5639..5812)
                     /db_xref="GeneID:96288643"
                     /locus_tag="IE233_RS02955"
                     /old_locus_tag="GCM10010326_06210"
     CDS             complement(5639..5812)
                     /codon_start=1
                     /db_xref="GeneID:96288643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735898.1"
                     /locus_tag="IE233_RS02955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06210"
                     /product="CsbD family protein"
                     /protein_id="WP_100573672.1"
                     /transl_table=11
                     /translation="MSGEEKGKSKVEQAKGKVKEAAGRAVGNERLEAEGRGEQAKGDAR
                     QAKEKIKDVFKH"
     gene            6054..6215
                     /db_xref="GeneID:96288644"
                     /locus_tag="IE233_RS02960"
                     /old_locus_tag="GCM10010326_06220"
     CDS             6054..6215
                     /codon_start=1
                     /db_xref="GeneID:96288644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031579.1"
                     /locus_tag="IE233_RS02960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06220"
                     /product="hydrophobic protein"
                     /protein_id="WP_167160694.1"
                     /transl_table=11
                     /translation="MVPLLLVLLLALILFGAGFALKILWWVAIVVLVLWLVGFVARPRG
                     GSSRWYRW"
     gene            complement(6494..7351)
                     /db_xref="GeneID:96288645"
                     /locus_tag="IE233_RS02965"
                     /old_locus_tag="GCM10010326_06230"
     CDS             complement(6494..7351)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240725.1"
                     /locus_tag="IE233_RS02965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06230"
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="WP_161249320.1"
                     /transl_table=11
                     /translation="MRTAEPETGHEVRVLPVIEDPARVAPRDARALSRQFFERLAVLEE
                     GTAEYQYARNTLIEMNMSLVRFAARRFRNFADEMEDVVQVGMIGLIKAIDRFELSRETE
                     FATFAVPYIVGEMKRFFRDTTWAVHVPRRLQERRSELARAREELESRLDRSPTVKELAA
                     LMDLSEDEVVEAQMAANGYNSASLDAALSGDEESGEAALADFIGAEDPAMDLVENFQSL
                     APLMAELSDRERLLLQLRFGEELTQSQIGEELGVSQMQVSRLLSRTVAKLRAGMFETAT
                     GATA"
     gene            7697..8662
                     /db_xref="GeneID:96288646"
                     /locus_tag="IE233_RS02970"
                     /old_locus_tag="GCM10010326_06240"
     CDS             7697..8662
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004955615.1"
                     /locus_tag="IE233_RS02970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06240"
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="WP_190026082.1"
                     /transl_table=11
                     /translation="MSPRRPAPAPLPRLHRIELDGTGPEDVVFDHAGRVLTGLGDGRLL
                     RIELPRRPGGPAHLAEIGRTGGRPLGLDLLADGRLLVCDAQRGLLRFDPDGTAGFDVLA
                     DSVAGQPLRFCSNAVAASDGTVYFTVSSRRYGLADWPSDIVEHRPTGLLVRLAPGGEPE
                     VLLDGLQFANGVALAPDESFVVVAETGARRLTRWWLPGAEAGRHDTLARDLPGFPDNMS
                     RSPGGGFWVALAGPRTAPLDWLHRTAPPVRRAAAAALRLLPPLPAHAAGVVEVDVRGRG
                     IRQLADAGRQFRMATGVAERDGRLVLGSLVEDAIAWCDLR"
     gene            complement(8756..9919)
                     /db_xref="GeneID:96288647"
                     /locus_tag="IE233_RS02975"
                     /old_locus_tag="GCM10010326_06250"
     CDS             complement(8756..9919)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240938.1"
                     /locus_tag="IE233_RS02975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06250"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_190026083.1"
                     /transl_table=11
                     /translation="MTYTEASMDALRQAGDELADATVATLFERGEVGKFNTLMRYVSTV
                     GAPLPDGLPDVAREYLQVTSAPPPWVDWGEMERARLFFIDNNVHISTALSFASMPACYV
                     VPHVAKLLSATHGLKYPSKRMAETGQFTVYLMQPDAFEAGSRFIPAAQKVRLLHASIRH
                     HLKRENRWDTEALGTPICQEDMIGGQMFFSLLVLDSLHRLGIHMSTEGAEAYYYAWRVV
                     GAMLGIDQETVPKSLEEAREFLDLYMVRHMAPSDEGAELTRQLIDLYEEIVPGTFFDPI
                     VSALIRHLVGDTCADWLQVPRTRWDTVVKAVPHLLGVLETIEDRSPLGAWALDRIGHLT
                     AVLELSSLTRGRVMHYAIPEQLKKDFGVAGTVARTHRWTPPTATVPS"
     gene            complement(10001..11053)
                     /db_xref="GeneID:96288648"
                     /locus_tag="IE233_RS02980"
                     /old_locus_tag="GCM10010326_06260"
     CDS             complement(10001..11053)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288648"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031263.1"
                     /locus_tag="IE233_RS02980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06260"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_161249314.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-36, bitscore:
                     122.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRWEPAAFKARVDEVLRHFVAAEADELSAIDPLLGPVAGQLEA
                     AVADGKRLRSAFCYWGWRAVGQPDSDALVRAAASMELVHAAAVVHDDLIDDSPLRHGRP
                     SAHIALRGAVRRRPRAVAAARSLAMLVGDLLMSLAGQLFATSGLPAAYLARARPLWSLL
                     ARELIAGECLEILRTGAPPDISASLKVIRYKTAKYTVEQPLLIGAALAGAGERLRQGYS
                     AYGLPLGEAFQLRDDLLGLFGDPERTGKANSDDVRGHRPTALLAETWRLADAGERERLG
                     SLLGRRDLDEEGLDEVRAVMRGLKAPDRIELMIGERVDEALTVLGTLNAPAPATAALTA
                     LARSAAIRLS"
     misc_feature    complement(10724..10726)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11046..11321)
                     /db_xref="GeneID:96288649"
                     /locus_tag="IE233_RS02985"
                     /old_locus_tag="GCM10010326_06270"
     CDS             complement(11046..11321)
                     /codon_start=1
                     /db_xref="GeneID:96288649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059135.1"
                     /locus_tag="IE233_RS02985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06270"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_161249317.1"
                     /transl_table=11
                     /translation="MTGEAGRREGLDEQAVLLAAGLADLAVSTVGSALGVVRGLLRRSD
                     TAEMAADAEHDLLARGRLVMDRYAAAPPAHLEVLARHALARRAGDV"
     gene            11574..12344
                     /db_xref="GeneID:96288650"
                     /locus_tag="IE233_RS02990"
                     /old_locus_tag="GCM10010326_06280"
     CDS             11574..12344
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288650"
                     /inference="COORDINATES: protein motif:HMM:NF023144.5"
                     /locus_tag="IE233_RS02990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06280"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_202519225.1"
                     /transl_table=11
                     /translation="MIPSHVDDTLPELAPFLHEVRAHRPDDGTWCEAWTVRDVLAHQTG
                     NAEELARVLEAFLAGSPVETRGFDREEPYRRMSDPDLWAAFMSRCEHLAEIAAAAERDL
                     SPDTEIMWTGRSVNVPFFAEHMREELILHRWDLSGDDRTAVQALAEPWMTEHSVVSVGR
                     PLLVRGSTGLDLGPDGRIEGRLRCPGTDDVVVTADAGGTGIRLAAPEGPATIESDAATR
                     VLLLWGRRPADPSRWSSSAGPDALRRVRTLLSGY"
     gene            complement(12354..12875)
                     /db_xref="GeneID:96288651"
                     /locus_tag="IE233_RS02995"
                     /old_locus_tag="GCM10010326_06290"
     CDS             complement(12354..12875)
                     /codon_start=1
                     /db_xref="GeneID:96288651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566593.1"
                     /locus_tag="IE233_RS02995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06290"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_373300094.1"
                     /transl_table=11
                     /translation="MTFEPKNSELPAESAESAEAAEPAVSVVGPDDGEMIVLGTTRLRL
                     LEDGSNTGHRLGIAESVLAPHTPGPPQHRHAQHDEGFYVISGTVRFTVRDRDYDATAGT
                     LVMVPPGAPHTFANVTDQPAVMLSTFTPDLYVQYFRDLQDMVAGGRAMTPEATIRTMSR
                     YATEPAADFG"
     gene            12955..13851
                     /db_xref="GeneID:96288652"
                     /locus_tag="IE233_RS03000"
                     /old_locus_tag="GCM10010326_06300"
     CDS             12955..13851
                     /codon_start=1
                     /db_xref="GeneID:96288652"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014150773.1"
                     /locus_tag="IE233_RS03000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06300"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_190026084.1"
                     /transl_table=11
                     /translation="MELRTLHYFVAVAEELHFGRAARRLHMSQPPLSRAIKQLETDLGA
                     SLLDRSPLGVALTPAGAVLLDEARALLLGADRVRGRVARAAGTATLTLGILGDSADPRV
                     LRLADAYRRRHPLVEVRVREADLSDPTCGLHAGTVDVALTRGPFDETGLTVHELRTDPV
                     GALLRTDDPLAGRVALTLADLADRRWFVFPEGTDPRWQAYWNGGEPREGPVVRAVQECR
                     QAVLWNGTVGLTLLDHDPGEGLTVVPLTDMPPSRLVMAWRESAPTPLIHSLARTAATVH
                     GAGVRGVSDRGAAVHGA"
     misc_feature    12971..12987
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.15"
                     /tool="antismash"
     gene            14051..15187
                     /db_xref="GeneID:96288653"
                     /locus_tag="IE233_RS03005"
                     /old_locus_tag="GCM10010326_06310"
     CDS             14051..15187
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288653"
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146206.1"
                     /locus_tag="IE233_RS03005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06310"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190026085.1"
                     /transl_table=11
                     /translation="MRSKNVLISGASVAGLTLAHWLQRAGFRPTVVERAPGLRRGGQAI
                     DIRGSALGVVERMGLLDKVRSATTDMRGMSFVDARGEELSRSTEATLTGGLIDNDDVEI
                     MRDDLTTFLFDTSRYGTEYLFGDVITSVEQNDDTVEVRFRHERPRSFDLVIGADGLHSN
                     VRRLAFGPESDFLHFLGSYLAIFSVQNYLGLDHWQTYHTSDDLLVGVYSVRQNTEARAM
                     LLFDSPELDYDHRDLDQQRSILAERFAGVGWETPRLLESMRDAPDFYFDSMSQVHLDHW
                     SNGRVGLVGDAGYCASPRSGQGTSIAMVGAYVLAGELANHPHDHRAAFTRYQDLMRDYV
                     RNNQRLAQNRAADISSTPPDELARAANSITLPDWPHLG"
     misc_feature    14204..14206
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15239..16963)
                     /db_xref="GeneID:96288654"
                     /locus_tag="IE233_RS03010"
                     /old_locus_tag="GCM10010326_06320"
     CDS             complement(15239..16963)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288654"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088719.1"
                     /locus_tag="IE233_RS03010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06320"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_190026086.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.6e-19, bitscore:
                     65.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADALLFNPHTYDPKHFDPETRRLLRATVDWFEQRGKRRLIEDYR
                     SRAWLADFLAFSAKEGLFATFLTPASAAGDDEGDKRWDTARIAALNEIFGFYGLDYWYA
                     WQVTILGLGPVWQSDNAAARTRAAELLAQGEVFAFGLSEKTHGADIYSTDMLLEPDGDG
                     GFRATGSKYYIGNGNAAGLVSVFGRRTDVEGPDGYVFFAADSRHEAYHLVKNVVDSSKF
                     VSEFRLENYPVRAEDVLHSGRAAFDAALNTVNVGKFNLCTASIGICEHAMYEAVTHAQN
                     RILYGRPVTAFPHVRRELTDAYVRLVGMKLFSDRAVDYFRSAGPEDRRYLLFNPMTKMK
                     VTTEGEKVIDLMWDVIAAKGFEKDTYFAQAAVEIRGLPKLEGTVHVNLALILKFMRNHL
                     LNPADYAPVPTRLDAADDAFLFQQGPARGLGSVRFHDWRTAYDAFAELPNVARFREQAD
                     ALCEFVTTAAPDEEQSRDLDLLLAVGQLFALVVHGQLILEQARLTGLDADVLDELFAVL
                     VRDFSAHAVELHGKDSATSEQQGWALGAVRRPVVDEVRSARVWDRVEALSGTYEMAP"
     gene            complement(17100..17654)
                     /db_xref="GeneID:96288655"
                     /locus_tag="IE233_RS03015"
                     /old_locus_tag="GCM10010326_06330"
     CDS             complement(17100..17654)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288655"
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640749.1"
                     /locus_tag="IE233_RS03015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06330"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_161248018.1"
                     /transl_table=11
                     /translation="MALEHAILVSLLEKPGSGYELARRFDRSIGYFWAATHQQIYRILK
                     RMEGDGWIDAREVAQAGRPDKKEYSVADPGRAALSRWLHEPIEPESVRHELAVKIRGAA
                     FDDPAALLHEVERHRRAHADRLAHYLAGELRDFTGPEAPAPDPGRELQHVVLRGGIAYE
                     RMTLAWLDDVIATLHRLGAGR"
     misc_feature    17739..17751
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.92"
                     /tool="antismash"
     gene            17822..19150
                     /db_xref="GeneID:96288656"
                     /locus_tag="IE233_RS03020"
                     /old_locus_tag="GCM10010326_06340"
     CDS             17822..19150
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288656"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088614.1"
                     /locus_tag="IE233_RS03020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06340"
                     /product="cytochrome P450"
                     /protein_id="WP_190026087.1"
                     /sec_met_domain="p450 (E-value: 2.9e-69, bitscore: 230.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHIPGPEPRTDGGAGAIAAAGGLHHYQRLLHATYGPVVRFQLPGA
                     ETAVSIADPVLLEATAHLDERPERLFDFLTPLFEAGNVQVLPIEEHTPWRRLLLSVLAG
                     RPSHERHFARFTELTTALADGWAEGAHAGTDQEPVALQKDLTALTLRMICAYALGGDAT
                     DADAVVTAFEVVLTEYLGRLYEAPSPEREGERNTRTAEALSLLRTTVDRIVAAHGTRDA
                     ADRSDLIGALVAAGEQPARIRDTVMATLLAAHHTTGVAVSWTLHLLGGHPEAADRVADE
                     LRRVLGERMAPDYADLRRLTYLDMVLKESMRLFPPGPYGARETTEAITLGDYEIPAGAT
                     VFYPFWAVHMNPEYWPDPERFQPERFTPDEVTKRPRLAHIPFGFGPRSCEGAQLATIEA
                     QLILAILLKRFRFRPAPGHKVVPIERFVLWAEDDIRMTVRPRE"
     gene            complement(19201..19851)
                     /db_xref="GeneID:96288657"
                     /locus_tag="IE233_RS03025"
                     /old_locus_tag="GCM10010326_06350"
     CDS             complement(19201..19851)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288657"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992347.1"
                     /locus_tag="IE233_RS03025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06350"
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="WP_161248014.1"
                     /transl_table=11
                     /translation="MPVPADPTVLHPMPGQPRVVLLKPLVTSPLIEVGEYSYYDDPDDA
                     TAFETRNVLYHYGPEKLIIGRFCALGTGVRFIMNGANHRMDGPSTFPFPTMGGSWAERF
                     DLLTGLPNRGDTVVGHDVWFGHGATVMPGVRIGHGAIIAAGAVVTSDVPDYGIVGGNPA
                     RLIRSRYSEPDVARLLAVAWWDWPAEFITEHVRTIMSGSIDDLEAAASKSPTA"
     misc_feature    19951..19962
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.36"
                     /tool="antismash"
     gene            complement(19980..20630)
                     /db_xref="GeneID:96288658"
                     /locus_tag="IE233_RS03030"
                     /old_locus_tag="GCM10010326_06360"
     CDS             complement(19980..20630)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96288658"
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151865.1"
                     /locus_tag="IE233_RS03030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010326_06360"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_161248012.1"
                     /transl_table=11
                     /translation="MAAHGATNGQLGRRERKKAQTRRTIAETALRLFLERGYDAVGVRE
                     VAQEADVATATLFAHFPSKEALVFDQDDEQEEALLDVVRARPEGVSIPEALRRWFHGMV
                     DAARNEPDLDRFHRLIETTPALRDYSARMWLRHEQALADVIAADIGLAAPDTASRLVAR
                     TALGVIPSITSLDEGARIIDVTFDFVEAGWTATAPAADAGATAGGRQSRARAR"
ORIGIN
        1 gtctgcgagg ccgacgcgat cgccgcccgg gccgcacgcg agcggatcgc cgtctcgctc
       61 gaacgggccg tgcagcgagg caagttgggc cgcggctccg ccgaggacgc tctgtcccgc
      121 atggtcttca ccggcagtct cgacgacttg gccgaccgcc agctcgtcat cgaggccgtc
      181 gtcgagaacg cctcggtcaa aacagaggtc ttcgcccgcc tcgacaagat cgtcgaagac
      241 ccggacgcga tcctcgccac caacacgtcc tccatccccg tcatgcgcct gggcatggcc
      301 acccggcgcg ccgaccgcgt cctggggctg cacttcttca accccgtacc ggtgctgccg
      361 ctggtcgaga tcgtgtcctc gctgcacacc acgtcgcgaa cgaccgatgc tgtggcggcc
      421 ttcgccgagc acaccctggg caagacggtc gtacgttccc aggaccgggc gggcttcgtc
      481 gtcaacgcgc tcctcgtgcc ctacctcctg tcggcgatcc gcatgacgga gtccggcttc
      541 gccaccccgg ccgatgtgga cgcggccatg gagctgggct gcgcccaccc gatgggcccg
      601 ctgaagctgg ccgatctgat cggcctggac acggtcgccg ccatcgcgga atccctctac
      661 gaagagttca aggaacccct ctacgccccg ccgcccctgc tgcagcgcat ggtggaggcc
      721 gggctgctcg gccgcaagag cggccgcggg ttccacctct acgaccgggg ctgaggggcc
      781 cgggtcggcc gccggacaga gggccggcgg ccactgtgga gaggggcgtg gaacggattg
      841 ggagatccgt tccacgcctc acgcctcacc cgtccacgcc ttggcaccgg cccgcacgct
      901 cgcccgctcg cccgcgcccc cgtcaccaac ggacggcagt gaagtcgacc ggccggggtt
      961 cgagcagccg ggtgcgttcc gtcagcgcgc gcagccggcg ggacatctcg tcggcgggca
     1021 gccggtggcg gtcgccgtgg cccggcaaca cccactcgaa gcggagccgc tcggccgtcc
     1081 tcgccagtga aacggcctgt tcctcgatgg agtaccaggt gacgctgtcc gccacctcca
     1141 ggtccccggt ggcccgcgac cagtagaagc tgtcaccgct gaagcagtac ctgtcgtccg
     1201 cgaggtagtc gtccgcgagg tagagcacgc tcccccgggt gtggccgggc agcgggtgga
     1261 cggtcacccc ctcggcgatc tccacggggt caatgccccg gatcacacag tcggcgtccg
     1321 gggccgcgtc gaggtctccc tcgtggatcc acaggcgggc gccgaaatgg tcggcgtaac
     1381 tccggccgtg tgcggcatgg tcccggtgtg tcagcaggac atccgtcacc ggccccgacg
     1441 ccgcgtagcg atcggcgagt tcggcgctcc agcgcggggt gtcgatcatc atcgccgtgc
     1501 cgttggggcg cagcaggagg taggagttgg ccccggcggt gtgccgggaa ttgtgcccgc
     1561 agatccacag accgtcgtcc aactccatcg gaaacgggtc gcggctccgg tccgcccgcc
     1621 cggacctggg ccggatcgaa cgtgtcgggc aggcgaagac ggcggcgtgc aggcgccgtg
     1681 tctcctccgc accgctgggc gggcgcagga tctgcgactt cccgccggtc tcgccgatca
     1741 gctcgggcgc gaactggcgg gcgacatcgc agttggtgca acggtcgtcc acgtaccagt
     1801 cgtccatggc agtgctcctt cgacagaggg ggcgagctgg acacgggccg ccaccgaccc
     1861 gccaactccc ttacctcgct tgctgattgc agtggtcgcg tggccaagca tgcacacgcg
     1921 accggccata tcgcacatgg ccgtccgctt gcgattgcgg cgaggtgctg ctctgcgcta
     1981 cctcggcggg atgccgttcc ggaccgcctc agtgaacagc gccgagcgtc cttcccgtgc
     2041 tgagcaccgc gccgatttcc gccgactggc ccgggggcgc cttcacggcg agggtcgtgc
     2101 cggtcgtgtc ggcgcgcacc tggcccgtca cggtgatccg ggtgacggcg cggcttcccg
     2161 cggccaggag gtaggaggcg cccgagggtg cgctccagtg ggcgtcggcc aggatgtgct
     2221 ggttgaagcg gctgcagtac gaggtgtccc gcgcgtcggc gatcagggtg ccgggctcgc
     2281 gcgccgccgt cgtgggcggc tggaaccgta cgacggcccg gcccggaccg ttccaggtgt
     2341 cggccctcga acacagccac tccgcctggc ccgcgttctc cggcaactgc tgttccgcga
     2401 agacccagtt gttgaccgac cgtacgccgc cccccaccgc ggaccgcaac gtacacgccg
     2461 tgtgggacca gctcaccagc gccgccgtgc tcgtggcctc gcggggctga cgggccggga
     2521 cgccgccgcc cggcggcggc gtgtaggtga ggtggacggg tgacaggtca ccgaggtcgg
     2581 tgagcaggaa ggcgtgcttc tcggcgatgc gctcggacga acgcagttgt agggcaggcc
     2641 agttggagca gggcccggtg aggtcggggc gagccaccgc gtcactgacg ccgtcgtcgc
     2701 cgacgtgcag tgggcgggcc gggctgtcgg gggcgagcag gtcgcgcgtg gtggattcgg
     2761 ccacccaggg agcgagcagg aagcgtgtcc ggctcccggt ccggctgagg acgagcgcgg
     2821 ccgccgtggt gacatcggcg ttgtcggcgc gcgagaaggc gagttcggcc ggctgcccgg
     2881 tggtttccgc gtagcgcacg accctctcgc cgtcgtacag gaggaccacg tcggcgtcgt
     2941 ccacccttcc cgcgtacagg agttggggcg gcgcagccgt cggtcccgtc ccggtcctgg
     3001 gcgcggccga cacctggaca gcggtgcccg gccgcgccca ggcacggagc gcgcgcccca
     3061 gcagggcctg gtcgtcgacc aggctgccgc gcgcgggcca gaccgtgaag tcgatgcgcg
     3121 agctcgactg ccaggccgtg cccggcgcgc gccccactgc ccccgggtcg accatcgcga
     3181 cgccgacggc cgagggggtg gtgggttccg gcgacgccgg gtccttggcg ctctggccca
     3241 ccgtgagcat caccgcgacg aggagagcgg cagccgcccc ccagcgccgc caatggcgac
     3301 ggcgcagcag gtccgtgggc cgggcctgca ccgtgcacgg gtcgaactcg acggagtcga
     3361 gcagcaaccc cgcccgggtg ccgtcgtcct gtgggcccag ggccttggca gcgcgcagcg
     3421 cggcctccgg gtccgggact ccggccgccg tcagcagctc ggcggcggtg tccgaggcgt
     3481 acccctccag gtgctgcagc acgaaggccg cccggacccc ggccggtacg gtcgccaact
     3541 gctgctccag ggccagttcg tccgcaccgc cgatacgggg tgtcagcctc agcccccaca
     3601 cggcgggcag cgcgggccgc acggcccggc gccagcgggc ggcaccgtgc tcgtaggaaa
     3661 gggccgcgcc cactacgcgg cgcacgatcc agccgagggc cggcgcccgg tcgtcgcgcg
     3721 gcgcgggcac ccggcccttc ttgatcggcg tcggccgggc gggcagcgcg ttctgtacca
     3781 cgccgtgcgc ggcgagcacg cgccgatgac ggccgagccg gggaggaagg atgaggtagg
     3841 ccagccggac gagccggggg tagtgctcga cgagcgtcgc ctccgcctgg ccgagcgcgg
     3901 gcaccggacc ggcaggacgg gggtgacgct cgcgttgtgg ggctgacatg gtggaacacc
     3961 ttctccgggg cggacgttgt ggctttgccc ttcaaacgag cgaatcggat gacagtcaca
     4021 ccgcgagcgc ctcttggggg cgtgcgggtg ctttccgggc gccgtacgcg cctcccgtat
     4081 cctcccgggg cagtcgctcg ttcccgcttc catggaagag tgcgctcatc cgatcaaagg
     4141 cccgcgcgtg acgaagcgtt gttcctcccc gccggaggag gccggcgccc gaccgccgcg
     4201 aaacgagagc ccgccaccca cgaacgcgca tgcgcagtgc gggccgggcg ggagcgacgt
     4261 gagcttcaac cggtggggca ccgtggtgtt ctgacggcca tgcggggccc gcgcgcccgc
     4321 gccacggcgg aacgacactc cccgtcctgt cgggtacgga atcatcgcga gccagaacgg
     4381 gccgacggcg gccggtacgc gcgcccacgt cggcccgcgt caccgcgatc cgccgtcgcc
     4441 cgtctctcct acgagcggga ggaccgcatg cgtaccacgc acatcatggc caatcttccg
     4501 gtggccgaca tcgcgacggc caagagtttc taccgggact atctcggcct gagcaccgag
     4561 gagttcgacc tgacatgggt ggcccgctgc acatcgcccg attccgcggc gagcgtccag
     4621 ctcgtgacgc acgacgcgac ggcgcccgag gactcggtca tctccgtcct gaccgatgac
     4681 gtcgaaggcg cttacgccga ggcgcggcgg ctcgggttcg agatcgtgca tccgctgacc
     4741 acggagccgt ggggccaccg tcgcttcttc gtccgggcgc cggacggcaa cgtgatcaac
     4801 atcggattcc acggcgacgt gtgacggccg cgcagaccgg gagggcctgg agatcccgaa
     4861 gggtctggag gccctgggac ctcggagagc cgcctgagac cccgggcagg cgccgcgggt
     4921 cccgggccgc ggacgacggt gcgaggcggc gttggggacc ggtgcccgca tcctaatcgc
     4981 ggcggctccg gattcacccg aacagcgtcc tgaacaggcg tgggcccctc aggggtggtg
     5041 gtgtgaagtg ctctcccccg taggaggacc gccatgtacg aaatgcacgt cggcacggcc
     5101 gttaccggca cccgccgggt gtggcacgtc gtcgcccatg accagcgcgc caccttgtgc
     5161 ggccagcccc tcgaacccgt cgaggacact cagaccgacc accactgtct gccctgcatg
     5221 tcggccttcc agcgcctcat gcaagccgtc gagcccgcct gacggtattt ggcatcgagg
     5281 gcgtgcccgc cctccggagg cgtgatggac cgcatctgcc tgacatgttc atcgaagaaa
     5341 tcggcggcat cggagcccgc gaggccgtcc accgcgatct tcaccttgtt cgtgcttttc
     5401 caggtgacct ggggtcgcag aggccgcctc gcactggctc tgcgtcggcc gtacggggcg
     5461 acgtaggcgt tgccgccgct tctgtcccgc gcccgtccca agaacgatcg cgtccggggt
     5521 gccgccacgg acgcggcacg aggacgcacg aggacggggg cggggccggc cgaatctgcc
     5581 ggccgggccc gcccccgcgc cctgacccgc tcggtcagcg cgtcgagtgc cagtgcgctc
     5641 agtgcttgaa gacgtccttg atcttttcct tggcctggcg ggcgtcaccc ttggcctgct
     5701 cgccgcggcc ctcggcctcg aggcgctcgt tgcccacagc gcggccggcg gcctccttga
     5761 ccttgccctt ggcctgctcg accttcgact tgcccttttc ctcaccggac acaacaacca
     5821 ccactcccac aaatcgacgt cgaactgcga cagcagtact cctcgccgca ttcggccgat
     5881 ccaaaccgca gagacccaaa ggaagtccac cgccttctcc cagcgtacgg gattgcgcca
     5941 gaattccgga gggcgaggcg attcgggcgc ttgagccagg gaatatgtat caagccgatt
     6001 cgagtgcgtg acgggtgtct tccgggcacg cggtggactg gaggtagata gccatggttc
     6061 cccttcttct cgtgctgctg ctcgccctga tccttttcgg cgcgggcttt gccctcaaga
     6121 tcctttggtg ggtggccatc gtggtcctgg tcctgtggct ggtcggtttc gtcgcccgcc
     6181 cccggggcgg cagctcccgc tggtaccgct ggtagccgag cggcacgcag accacgcaga
     6241 cgtaggacag caggcatggg acaggggccg gacctcgaac aggtctccgg cccctgttcc
     6301 atgtcatttg tcgtacgtct tctgtcgtat accttcggct gccgtatgcc gtcggcatcg
     6361 atgcggacgg gaaacgaaaa aggaagccga tgggatgaat caggactggc ctgaattcaa
     6421 agcccggtcg gcttcctttt cctcattcgt tcaacgtccg gttgtcctgg atcgcactgt
     6481 cccggacggc acttcaggca gttgcgcccg tggcggtctc gaacattccg gcgcggagct
     6541 tggcgacggt acgcgacaga aggcgggaga cctgcatctg ggaaacgccc agctcttcac
     6601 cgatctggct ctgggtgagc tcctcgccga agcgcagctg cagcaacagg cgctcccggt
     6661 cggagagttc cgccatcagc ggggcgaggc tctggaagtt ctccaccagg tccatcgccg
     6721 ggtcctcggc accgatgaag tccgccaggg ccgcttcccc gctctcctcg tcgcccgaga
     6781 gcgcggcgtc cagggaagcg gagttgtagc cgttggccgc catctgcgcc tcgacgacct
     6841 cgtcctcgct gaggtccatg agggcggcga gttccttgac ggtgggcgag cggtccagac
     6901 ggctctcgag ctcctcgcgg gcccgggcca gctcgctgcg gcgctcctga aggcgtcgcg
     6961 gcacgtggac ggcccaggtg gtgtcacgga agaagcgctt catctcgccg acgatgtagg
     7021 gcaccgcgaa ggtcgcgaac tcggtctcgc gggagagctc gaagcggtcg atcgccttga
     7081 tcaggccgat catgccgacc tggaccacgt cctccatctc gtccgcgaaa ttgcggaagc
     7141 gacgagcggc gaaccgcacg agggacatgt tcatctcgat cagggtgttc cgcgcgtact
     7201 ggtactcggc cgtgccctcc tcaaggaccg cgaggcgctc gaagaactgc cgggacagcg
     7261 cccgcgcatc gcgaggagcc acgcgcgccg ggtcctcgat caccggaagc acccgcacct
     7321 cgtgtccggt ctccggctcg gcggtcctca tcgtcgcagt cgctacggca gtcacagcca
     7381 ctcccctcct cgtcccccgt acaaataaca ttcgtttcgc gtctgccccg aactcaccga
     7441 tccattcgca cgagattcgg acccgtttcc cggcggtccc gccgaggccg tgtccgccgc
     7501 ccggccacgg ggttttcggc gcgcgggaac ggtcacccgt gccgggggcc cgtaccaggc
     7561 ggacgcactc gcgccgccgg atcacacggg ccccggagtc ccccggaacg atacgcgcga
     7621 agctttgaca cctgtccgcg atgagaaggg ccgccatgcc gactcccacc ggaacccgcc
     7681 ccgccagggg tggcgcatga gccctcggcg ccccgccccg gccccattgc cgaggctgca
     7741 ccgcatcgag ctcgacggca ccggccccga ggacgtcgtc ttcgatcacg cgggccgggt
     7801 gctcacgggg ctcggggacg gccgcctcct gcggatcgag ctgccccggc gtcccggcgg
     7861 acccgcccac ctcgcggaga tcggccgcac cggcgggcga ccgctcgggc tcgacctcct
     7921 cgccgacgga cggctgctgg tgtgcgacgc ccaacgaggc ctgctccggt tcgatcccga
     7981 cggcacggcc gggttcgacg tgctggccga ctcggtggcc gggcaaccgc tgcggttctg
     8041 cagcaacgcg gtggcggcgt ccgacggcac cgtctacttc acggtgtcca gccgccggta
     8101 cggcctcgcc gactggccga gcgacatcgt ggagcaccgc ccgacaggcc tgctcgtgcg
     8161 cctggccccg ggcggggagc ccgaggtcct cctggacggg ctgcagttcg ccaacggggt
     8221 ggctctcgcc cccgacgagt cgttcgtcgt ggtggccgag accggagcgc gccggctcac
     8281 ccggtggtgg ctgccaggtg ccgaagcagg ccgtcacgac acgctcgcac gggacctgcc
     8341 gggcttcccc gacaacatgt cccgcagccc gggcggcggg ttctgggtcg cgctcgccgg
     8401 tccccgcaca gcgcccctgg actggctcca ccggaccgcg ccgccggtgc gccgggcggc
     8461 ggccgccgca ctccggctgc tgccaccgct gcccgcgcac gccgccggtg tggtggaggt
     8521 cgacgttcgg ggccgcggga tacgtcaact ggcggacgca gggcggcagt tccgcatggc
     8581 cacgggtgtg gccgagcggg acgggcgact ggtcttgggc agcctggtgg aggacgcgat
     8641 cgcctggtgc gaccttcggt agacgcccgg agcggcccgc tcccgcccgt acccgtccgc
     8701 gcgtgggcgg gccggccgga caggaaggaa ccgtggcgat gagtgggtcg gccggtcagg
     8761 aagggacggt ggcggtgggc ggcgtccacc ggtgggtgcg ggccactgtt ccggcgacgc
     8821 cgaagtcctt cttgagctgc tccgggatgg cgtagtgcat gacgcggccc cgggtgagcg
     8881 aggacagttc gagtacggcg gtgaggtggc cgatgcggtc gagcgcccag gccccgagcg
     8941 gggagcggtc ctcgatcgtc tccagcacgc cgaggaggtg cggcaccgcc ttgacgacgg
     9001 tgtcccagcg ggtgcgcggc acttggagcc agtccgcgca ggtgtcgccg acgaggtggc
     9061 ggatgagagc ggagacgatc gggtcgaaga aggtgccggg cacgatctcc tcgtagaggt
     9121 cgatgagctg ccgggtcagc tcggcgccct cgtcggaggg tgccatgtgc cgcaccatgt
     9181 agagatcgag gaactcccgt gcttcctcaa gcgacttggg gacggtctcc tggtcgatgc
     9241 cgagcatcgc gccgaccacg cgccaggcgt agtagtacgc ctcggctcct tccgtggaca
     9301 tgtggatgcc gaggcggtgc aggctgtcca ggacgagcag ggagaagaac atctgcccgc
     9361 cgatcatgtc ctcctggcag atcggggtgc cgagcgcctc ggtgtcccag cggttctccc
     9421 gcttgaggtg gtggcggatg gaggcgtgca ggaggcggac cttctgcgcg gcggggatga
     9481 accggctgcc cgcctcgaag gcgtcgggct gcatcaggta gacggtgaac tgcccggtct
     9541 ccgccatccg cttggagggg tacttgagcc cgtgcgtggc cgagaggagc ttcgccacgt
     9601 gcgggacgac gtaacacgcg ggcatggagg cgaaggacag ggcggtggag atgtgcacgt
     9661 tgttgtcgat gaagaacagg cgcgcccgct ccatctcgcc ccagtccacc cagggcggcg
     9721 gcgcgctggt gacctggagg tactcccgcg ccacatcggg cagcccgtcc ggcaagggcg
     9781 cgccgacggt ggagacgtac cgcatcaggg tgttgaactt gcccacctcg ccccgctcga
     9841 agagcgtcgc gacggtggcg tcggcgagtt cgtcaccggc ctgccgcagg gcgtccatcg
     9901 atgcctcggt gtaggtcatg acaggtctcc tcgtccttca cggtcgtcga cggcgggcgc
     9961 ggtccgccgc cgggcagcac ataggaaccc gcggtgcggg tcaggacaga cggatcgcgg
    10021 cggaacgtgc cagcgcggtg agggcggcgg tggcgggcgc gggggcgttc agcgtcccca
    10081 gcacggtgag ggcctcgtcg acccgctcgc cgatcatgag ctcgatgcgg tcgggggcct
    10141 tcaggccgcg catcaccgcg cggacctcgt cgagaccttc ctcgtccaga tcacggcggc
    10201 cgagaagcga gccgagccgc tcccgttcac ccgcatcggc caggcgccac gtctcggcca
    10261 gcagggcggt gggccggtgg ccgcgcacgt cgtcggaatt ggccttgccc gtgcgttccg
    10321 ggtcgccgaa caggcccagc agatcgtcgc gcagttggaa ggcctccccc agcggaagcc
    10381 cgtacgcgga atatccctgc cgcagccgct cgccggcccc ggccagggcg gcaccgatca
    10441 acaggggctg ttcgacggtg tatttggcgg tcttgtaccg gatcaccttc agcgacgccg
    10501 agatgtccgg aggggccccg gtgcgcagga tctccaggca ctcgcccgcg atcagctccc
    10561 gggcgagcag cgaccacagc gggcgggccc gcgccagata ggcggcgggc agtccgctgg
    10621 tggcgaagag ctgcccggcg agtgacatca gcaggtcccc caccagcatc gcgagtgatc
    10681 tggcggccgc gacggcacgc ggccgacggc gtacggcacc gcgtaacgcg atgtgcgccg
    10741 agggccggcc gtgccgcagc gggctgtcgt cgatgaggtc gtcgtgcacc accgccgcgg
    10801 catgcaccag ctccatcgag gccgccgccc gcaccagcgc gtcactgtcc ggctgcccca
    10861 ccgcgcgcca gccccagtag cagaacgccg accgcagccg tttgccgtcg gcgaccgccg
    10921 cctccaactg gccggccacc gggccgagca gggggtcgat ggccgacagc tcgtcggcct
    10981 ccgcggccac gaaatgccgc agcacctcgt cgacccgggc cttgaaggcg gccggctccc
    11041 accggtcaga catcgccggc ccgccgagcc agggcgtgcc gggcgagcac ctccaggtgg
    11101 gccggcggcg cggcggcgta ccgatccatc accagacggc cgcgcgccag cagatcgtgc
    11161 tcggcgtccg ccgccatctc agcggtgtcc gagcggcgca gcaggccccg cacgaccccg
    11221 agggccgagc ccacggtgct caccgccaag tcggcgagtc ccgccgccaa gaggacggcc
    11281 tgctcgtcca ggccctcacg tcgtcccgct tcccctgtca tggcttcccc tcaccccgcg
    11341 gcacagccgg acggcatccg tcatatgcca tccgttccag aatcgcggcg cccgccggtc
    11401 ctccgccggg gaactcacga tcgggtgagg gcatcgctcg tccgtgcggg ccgctcgccg
    11461 tggcggcggc cgagggcgcg cgggcacccg aaggccctgc gggcggtcgc ccgaccgggc
    11521 gccgttcggt cccggtggtt tgacgggcca cccgatcggg atacccgtgg cacgtgatcc
    11581 cctcccacgt cgatgacacg ctgccggagc tggcgccctt cctgcacgag gtgcgggccc
    11641 accggcccga cgacggcacc tggtgcgagg catggacggt acgggacgtg ctggcccacc
    11701 agacgggcaa cgccgaggaa ctggcccggg tcctcgaagc gttcctcgcg ggctccccgg
    11761 tggaaacgcg cggcttcgac cgggaggagc cctatcggcg gatgtccgac cccgatctct
    11821 gggcggcttt catgagtcgc tgcgaacacc tcgccgagat cgccgcggcc gccgagcgcg
    11881 atctgtcgcc cgacaccgag atcatgtgga ccggccggtc ggtgaacgtg ccgttcttcg
    11941 ccgaacacat gcgggaggag ctgatcctgc accgctggga cctgagcggt gacgaccgga
    12001 cggcggtgca ggcgctcgcc gagccctgga tgacggagca cagtgtggtg tccgtcggcc
    12061 gtcccctgct ggtcagaggc agcaccggcc tcgatctggg acccgatggc aggatcgagg
    12121 gccgtctgcg ctgccccgga accgacgacg tcgtcgtgac ggccgacgcc gggggcaccg
    12181 gcattcgtct cgccgccccc gaaggccccg ccaccatcga gagcgacgcg gccacccggg
    12241 tcctgctgct gtgggggcgc cgcccggcgg acccgtcacg ctggagcagc tcggcagggc
    12301 cggacgccct gcgcagggtc cgcaccctgc tgagcggcta ctgagccgcg gactcagccg
    12361 aagtcggcgg cgggctcggt ggcgtaccgg ctcatcgtcc ggatcgtcgc ctcgggcgtc
    12421 atcgcccggc caccggcgac catgtcctgg aggtcccgga agtactggac gtacaggtcc
    12481 ggggtgaacg tgctgagcat gacggccggt tggtcggtca cgttggcgaa cgtgtgcggg
    12541 gctcccggcg ggaccatcac gagggtgccc gcggtggcgt cgtagtcgcg gtcccggacg
    12601 gtgaaccgca cggtgccgga gatgacgtag aagccctcgt cgtgctgggc gtgacggtgc
    12661 tgcggcgggc ccggggtgtg cggggcgagc acggactcgg cgattcccag ccggtgcccg
    12721 gtgttgctcc cgtcttcgag gaggcgcagt cgcgtggtgc ccagcacgat catctcgccg
    12781 tcatccgggc cgaccaccga caccgcgggc tcggcagctt cggcggactc ggcggattcg
    12841 gcgggcagtt cgctgttctt cggttcgaag gtcatggctc gattgcactg cgcggcccga
    12901 cggctgtcca agaccagtcg cgcagggccg ataccggacg ggtatcgtcg cagcatggag
    12961 ctacgtacgc tgcactattt cgtagcggtc gccgaggaac tccatttcgg ccgggccgct
    13021 cggcgtctgc acatgagcca gccgccgctg agccgggcga tcaagcagtt ggagaccgac
    13081 ctcggcgcat cgctgctcga ccgctccccg ctcggagtcg ccctcacgcc agcgggcgcc
    13141 gtactgctcg acgaggcccg cgccctgctc ctcggggccg accgggtacg cggacgcgtg
    13201 gcccgtgcgg ccggtacggc gaccctcacc ctcggcatcc tgggtgacag cgccgacccg
    13261 cgtgtcctgc ggctggccga cgcgtaccgc cgacggcatc cactcgtgga agtacgcgtc
    13321 cgcgaggccg acttgagcga tccgacctgc gggctgcacg cgggaacggt cgatgtcgcc
    13381 ctgacccgcg ggccgttcga cgagaccggc ctcaccgtcc acgaactccg caccgacccg
    13441 gtgggcgcgc tcctgcgcac cgacgacccg ctcgccggtc gagtggccct gacattggcc
    13501 gacttggcgg atcgacgctg gttcgtcttc cccgagggca ccgacccgag gtggcaggcg
    13561 tactggaacg gcggggagcc gcgcgaaggg cccgtggtgc gagccgtgca ggagtgccgt
    13621 caggccgtcc tgtggaacgg cacggtgggt ctgacgctcc tggaccacga ccccggggag
    13681 ggcctgacgg tggtgcccct gaccgacatg ccgccgagcc gcctggtgat ggcgtggcgc
    13741 gagagcgccc cgaccccgct catccactcg ctcgcccgta ccgcggcgac cgtccacggg
    13801 gcaggcgtcc gaggggtttc cgaccgaggt gctgccgtcc acggggcatg accgtacgac
    13861 aacccatcag tcccgtcgca gcacgggcgc aacggcagat tgcccgaaac gcaaccatta
    13921 cttgccgatc tacgcattgc cgccgtggca ccccgttgcc aagactcgga ctcgacgagt
    13981 ccgcggtccc cggcgcgggg gccgcgtcat cgactcggcg aaccgggcat cagcagactt
    14041 ggggagcgcc atgcgcagca agaatgtact catatccgga gccagcgtcg cgggactgac
    14101 gctggctcac tggttgcagc gggccggctt tcgacccacc gtggtggagc gggcgcccgg
    14161 gctgcgcagg ggtgggcagg ccatcgacat ccgtggctcg gcgttaggcg tcgtggagcg
    14221 gatggggctg ctcgacaagg tccgctccgc caccaccgac atgcgaggca tgtcgttcgt
    14281 ggacgcccgg ggcgaggagt tgtcccggtc caccgaggcc acgttgaccg gcggtctgat
    14341 cgacaacgac gacgtcgaga tcatgcggga cgacctgacg accttcctgt tcgacacgag
    14401 ccgctacggc acggagtacc tgttcggcga tgtcatcacg tccgtcgagc agaacgacga
    14461 caccgtggag gtccgcttcc ggcacgaacg gccgcggagc ttcgatctgg tgatcggcgc
    14521 ggacggactg cactccaatg tgcggcggct ggcattcggt cccgagtcgg acttccttca
    14581 tttcctgggc agttacctcg ccatcttcag cgtgcagaac tacctcggcc tcgaccactg
    14641 gcagacgtac cacaccagcg acgacctgct ggtgggcgtc tacagcgtgc ggcagaacac
    14701 cgaggcgcgg gcgatgctgc tcttcgactc cccggaactc gactacgacc accgcgacct
    14761 cgatcagcag aggtcgatcc tcgccgagcg gttcgctggc gtcggctggg agacgccccg
    14821 gctgttggaa agcatgaggg acgcgccgga cttctacttc gactcgatga gccaggtcca
    14881 cctcgaccac tggtcgaacg gccgcgtcgg gctcgtcgga gacgccggtt actgtgcctc
    14941 gccccggtcg ggccagggca ccagcatcgc gatggtcggc gcgtacgtgc tcgccggcga
    15001 actcgcgaac cacccgcacg accaccgcgc cgccttcacc cggtaccagg acctgatgcg
    15061 ggactacgtc cgcaacaacc agcggctggc ccagaaccgg gcggccgaca tcagcagcac
    15121 cccgcccgac gaactcgccc gcgcggccaa ctcgatcacc ctgccggact ggccgcacct
    15181 cggctgaggt gtcggccggg cggtcggctc agcggccgcc cggcgacagc ggcatcggtc
    15241 agggagccat ctcgtaggtg ccggacagcg cctcgacacg gtcccagacc cgggccgagc
    15301 ggacctcgtc gacgaccggg cggcggaccg cgcccagcgc ccagccctgc tgctccgacg
    15361 tggcggagtc cttgccgtgc agctcgacgg cgtgcgcgga gaagtcccgt acgaggacgg
    15421 cgaagagctc gtcgagcacg tcggcgtcca ggcccgtcag gcgggcctgc tccaggatca
    15481 gctggccgtg cacgacaagg gcgaacagct ggccgacggc gaggagcagg tcgaggtcgc
    15541 ggctctgctc ctcgtcgggc gcggcggtgg tcacgaactc gcagagcgcg tcggcctgtt
    15601 cgcggaagcg ggcgacgttg ggcagctccg cgaaggcgtc gtaggccgta cgccagtcgt
    15661 ggaagcgcac ggaacccaga ccgcgggccg gaccctgctg gaagaggaag gcgtcgtcgg
    15721 ccgcgtcgag gcgggtcggg acgggcgcgt agtccgccgg gttcagcagg tggttgcgca
    15781 tgaacttgag gatcagggcg aggttgacgt ggaccgtgcc ctccagcttg ggcagaccgc
    15841 ggatttcgac ggcggcctgg gcgaagtagg tgtccttctc gaagcccttg gccgcgatca
    15901 cgtcccacat caggtcgatg accttctcgc cctccgtggt caccttcatc ttcgtcatcg
    15961 ggttgaagag gaggtagcgg cggtcttcgg gccccgcgga gcggaagtag tcgacggccc
    16021 ggtcgctgaa cagcttcatc cctacgaggc gcacgtacgc gtcggtcaac tcgcgccgca
    16081 catgcgggaa ggcggtgacg gggcggccgt acaggatgcg gttctgcgcg tgcgtgacgg
    16141 cctcgtacat cgcgtgctcg cagatgccga tcgaggcggt gcacaggttg aacttgccga
    16201 cgttgaccgt gttgagcgcg gcgtcgaagg cggcccggcc ggagtgcagg acgtcctcgg
    16261 cgcggaccgg gtagttctcc agacggaact cgctgacgaa cttcgaggag tcgacgacgt
    16321 tcttcacgag gtggtacgcc tcgtggcggc tgtcggcggc gaagaagacg tagccgtcgg
    16381 ggccttcgac gtcggtgcgg cggccgaaga cggagacgag cccggcggcg ttgccgttgc
    16441 cgatgtagta cttgctgccg gtggcccgga acccgccgtc gccgtcgggc tccaggagca
    16501 tgtcggtgga gtagatgtcc gcgccgtggg tcttctcgga caggccgaag gcgaacacct
    16561 cgccctgggc gagcagttcg gccgcgcggg tgcgggcagc ggcgttgtcg ctctgccaga
    16621 ccggtccgag gccgaggatg gtgacctgcc aggcgtacca gtagtcgagg ccgtagaagc
    16681 cgaagatctc gttcagggcg gcgatccgcg cggtgtccca gcgcttgtcg ccctcgtcgt
    16741 ccccggcggc ggaggccggg gtgaggaagg tggcgaagag gccttccttg gcggagaacg
    16801 ccaggaagtc ggccagccag gcgcgcgagc ggtagtcctc gatgagccgg cgcttgccac
    16861 gctgctcgaa ccagtcgacg gtcgcgcgca gcagcctgcg ggtctcgggg tcgaagtgct
    16921 tcgggtcata ggtgtgcggg ttgaacagca gcgcgtcggc catggccatt cgcctttccg
    16981 gctcggggag ttgaggaggg gtggacggaa gactcggtgg aacaaggagc gtgggtcggt
    17041 cggtggtgtg cgggcgggaa ggagcggctc gtgcgggcgc ccgcacggat gcgcccggtt
    17101 cagcgcccgg cgccgaggcg gtggagggtg gcgatcacgt cgtcgagcca ggcgagcgtc
    17161 atccgttcgt acgcgatgcc gccgcgcagc accacgtgct ggagctcgcg gcccgggtcg
    17221 ggtgcggggg cctcgggtcc ggtgaagtcg cgcagctctc cggcgagata gtgcgcgagg
    17281 cggtcggcgt gtgccctgcg gtgccgctcg acctcgtgga gcagggcggc ggggtcgtcg
    17341 aaggccgccc cgcggatctt cacggcgagc tcgtgccgga cgctctcggg ttcgatcggc
    17401 tcgtggagcc accgcgagag ggcggcccgg ccggggtcgg cgacggagta ctccttcttg
    17461 tccggccggc ctgcctgcgc cacttcacgg gcgtcgatcc agccgtcgcc ctccatccgc
    17521 ttgaggatgc ggtagatctg ctggtgggtg gccgcccaga agtagccgat ggaccggtcg
    17581 aagcgccggg ccagctcata accggagccc ggcttctcca acagcgagac gagaatcgcg
    17641 tgctcaagcg ccatgcccga atccttctat gcaactcgtt gcatagacaa gcggcaccgg
    17701 ccaggtgaga cacggctcac ccggtgccct tgtgccgggt gccgttgtca cgttggctgt
    17761 ctcccccagc acggcggcgg tccggcgggc cgtcccgcga tgcgagccat gaggagcggc
    17821 catgcacatc cccggtcccg agccccggac cgacggcgga gcgggcgcca tcgcggcagc
    17881 gggcggcctg caccactacc agcggctgct gcacgccacc tatggtcccg tcgtacggtt
    17941 ccagctgccg ggcgccgaga ccgcggtgtc gatcgccgat cccgtactcc tggaggccac
    18001 ggcccacctc gacgaacggc cggagcggct cttcgacttc ctgactcccc tgttcgaggc
    18061 gggaaacgta caggttctgc ccatcgagga acacacccct tggcgtcgcc tgctgttgtc
    18121 ggtcctggcc gggcgcccct cccacgagcg gcacttcgcg cggttcacgg agctgacgac
    18181 ggcgctggcg gacggctggg ccgaaggcgc ccacgccggt accgaccagg aacccgtcgc
    18241 tctccagaag gacctcaccg cgctgaccct gcgcatgatc tgcgcgtacg cgctgggcgg
    18301 cgacgccacg gacgcggacg ccgtcgtcac cgcgttcgag gtggtcctca ccgagtacct
    18361 gggccggctc tacgaggccc cgtccccgga gcgcgagggc gagcggaaca cacggacggc
    18421 tgaagccctg tcccttctgc gcacgacggt cgaccgcatc gtcgcggcgc acggcacgag
    18481 ggacgccgcg gacaggagcg atctcatcgg ggcgctcgtc gcggcgggcg agcaaccggc
    18541 gcgcatccgc gacaccgtca tggcgacact cctcgccgca caccacacga ccggggtggc
    18601 ggtctcctgg acgctgcatc tgctgggcgg ccatcccgaa gcggccgacc gggtcgccga
    18661 tgagctgcgg cgcgtactgg gtgagcggat ggcgccggac tacgcggacc tgagacggct
    18721 cacttacctg gacatggtcc tcaaggagtc gatgcggctc tttccgcccg ggccctacgg
    18781 cgcccgggag acgacggagg ccatcaccct gggcgactac gagattccgg ccggagccac
    18841 ggtcttctat ccgttctggg cggtccacat gaaccccgag tactggcccg accccgagcg
    18901 gttccaaccc gagcggttca ccccggacga ggtgacgaaa cgaccgagac tcgcccacat
    18961 tcccttcggg ttcggtcccc gcagctgcga gggtgcgcaa ctcgccacga tcgaggccca
    19021 gttgatcctc gccattctgc tcaaacgctt ccggttccgg ccggcgccag ggcacaaggt
    19081 cgtcccgatc gagcggttcg tgctgtgggc ggaggacgac atccgcatga ccgtgcgccc
    19141 ccgggagtga ccgaagcccg ctgcatctcg tgccccttgc cctgcccctt gccggatcgc
    19201 ttacgccgtg ggggacttcg aagcggcggc ttccaggtcg tcgatgctgc ccgacatgat
    19261 cgtccgtacg tgttcggtga tgaattccgc cggccagtcc caccacgcca ccgcgagcag
    19321 ccgggcgaca tccggttcgc tgtagcggct gcggatgaga cgggccgggt ttcctccgac
    19381 gattccgtag tcggggacgt cggaggtgac cacggcgccc gcggcgatga tcgcgccgtg
    19441 gccgatgcgc acgccgggca tcacggtggc gccgtgcccg aaccagacgt catggccgac
    19501 gacggtgtcg ccccgattgg gcaggccggt gagcagatcg aagcgctcgg cccatgagcc
    19561 acccatggtg gggaagggga acgtcgaagg cccgtccatg cggtgattgg ccccgttcat
    19621 gatgaaccgc actccggtgc cgagcgcaca gaacctgccg atgatcagct tctccggccc
    19681 gtagtggtag agcacgttgc gcgtttcgaa cgcggtcgcg tcgtccgggt cgtcgtagta
    19741 ggagtactcc cccacctcga tcagcgggga ggtcacgagc ggtttcagca gcaccaccct
    19801 tggctgcccg ggcatcggat ggaggaccgt ggggtcggcg ggtacgggca tggggcgctt
    19861 tcctttcgtg cggcgtgcgg cgtccggcgt ccggcgtccg gcgtccggcg tccggcgtcc
    19921 acgccatgat cgtcgcgcca cgctgccggg gaaagtgctt tctccgcccg ccactccaac
    19981 taccgggcgc gcgcccgact ttgacggccg cccgccgtcg caccggcgtc ggcagccggc
    20041 gcggtggcgg tccaacccgc ttccacgaag tcgaaggtca cgtcgatgat ccgggcccct
    20101 tcgtcgagcg acgtgatcga cgggatcacc ccgagcgccg ttcgggcgac cagccgggag
    20161 gcggtgtcgg gagcggcgag cccgatgtcg gcggcgatga catccgccag cgcctgctcg
    20221 tggcgcagcc acatcctggc cgagtagtcc cgcagggcgg gcgtcgtctc gatgagccga
    20281 tggaagcggt ccaggtccgg ctcattcctg gccgcgtcga ccattccgtg gaaccagcga
    20341 cgcagggcct cgggaatgga gacgccctcg gggcgcgcgc gtacgacgtc gagcagggcc
    20401 tcctcctgct cgtcgtcctg gtcgaagacc agggcctcct tggaggggaa gtgggcgaac
    20461 agcgtggcgg tcgccacgtc cgcctcctgc gccacctcgc gtacgccgac cgcgtcatat
    20521 ccgcgctcca gaaacagccg cagggcggtc tccgcgatcg tcctgcgcgt ctgggccttt
    20581 ttgcgctcac gccgcccgag ctgcccgttt gtcgccccat gtgccgccat gagacaacca
    20641 tagcagttgt gaagtcggaa cggttccgat tacggtactg ttccgaaagg cgctgcaccg
    20701 cggcgttccg accgccgact ggaggaagcc gtgaacacgt cacccatcac ccccggggac
    20761 ccgccgacga aggagccgtc cgggcgtcgg cgggcatggc tcgtcatcgt gtgtctgacc
    20821 ctgctcaact cgatcgggat gaccgtggtc tttccggtcc ttccgttcgt cacgctcgaa
    20881 tacgtcgacg cggggtcact cgccctgtgg gtcggcgtcc tcgaatcggt caacgccctg
    20941 tgcgcgttcc tcgtcgcgcc gctgctcggc ggcctgtccg accgggtggg ccgccgcccg
    21001 gtcctgatca tcagcgcctt cggcgccgcg gccggttacg cgatgttcgg tgt
//
