LOCUS       NZ_BMUT01000014        21335 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces hiroshimensis strain JCM 4586 sequence14, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUT01000014
VERSION     NZ_BMUT01000014.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces hiroshimensis
  ORGANISM  Streptomyces hiroshimensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 171175)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 90X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650335.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:32:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,830
            CDSs (total)                      :: 6,745
            Genes (coding)                    :: 6,620
            CDSs (with protein)               :: 6,620
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 25 of 125
            Pseudo Genes (incomplete)         :: 107 of 125
            Pseudo Genes (internal stop)      :: 4 of 125
            Pseudo Genes (multiple problems)  :: 11 of 125
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 123045
            Orig. end                         :: 144380
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUT01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21335
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21335
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21335
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11335](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11335
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1386..1400)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.29"
                     /tool="antismash"
     gene            1903..2370
                     /locus_tag="IE241_RS27895"
                     /old_locus_tag="GCM10010324_56960"
     CDS             1903..2370
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240763.1"
                     /locus_tag="IE241_RS27895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56960"
                     /product="hypothetical protein"
                     /protein_id="WP_190024620.1"
                     /transl_table=11
                     /translation="MKGTFEAVTGDACPPAGNASERASAVREAMEGLLQIRRLMNGHLT
                     EPLSGPADWERRQPVRAVALILEAAGIPPSALDAEGRRCATGYCVRPGEQPGTVRVEWL
                     GPPGSGAAARQHEALQRCARALEDAGWPALEYRGARKQRWLEAEPLVQRGR"
     gene            complement(2367..5756)
                     /locus_tag="IE241_RS27900"
                     /old_locus_tag="GCM10010324_56970"
     CDS             complement(2367..5756)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984306.1"
                     /locus_tag="IE241_RS27900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56970"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_229899904.1"
                     /transl_table=11
                     /translation="MTARHDGHDLPIGPPRRRALLALLLIRLGRVVPMELLVEELWGEE
                     PPRRAVATLQSHVSHLRRALQPAAGPDGVPVLRHRAGGYVLELDPARIDACRFELLVTE
                     GRRLLEQRDPAAARDRLTEALELWRGTPYGEFDGHPPLSDESARLEHLRLTAVESCAEA
                     RLALGAAEEVAGDLDREVRRHPARERLVGHLMTALSRLGRQAEALAVYERTRSHLAEEF
                     GVGTTAALRRVRTAILHQAGATAAAGETAPADHVVHVVHEVAPNTSGEQSGTAGAADAD
                     ADADADADANGTAEAPRTAATAGTGATADTDGAGDTRGMGDTGDTAEPGQPIGQSPFTG
                     RSEELQRLTTATASALAGHGHVAGVLGPAGVGKTRLLLELAPRLEAACASQGGARLEVV
                     WSHCFLSEGVPPYWLWTQVLRRLSVTRPDAFRRATEPFGSLLAPLMPERSACPGGSGPG
                     AGSDWGQARFLTHDAVCEVLLTLAGQRPLVLFLEDLHWADTASLDLLRLLSTRRQGHPL
                     GIVLTAREFEVESDATMRRMLSEVLRGPRTETLRLGGLSRQSVAAIVVAQAGPGVDAKV
                     VEVLHRRSEGNPYFVMQLLSLLGDPGSLRRPDAVDVLLTRVPTGVREVLHQRFAALPEP
                     VLQVLRLCAVIGSEVDTDLLHRTAAADEPVAEALESAIRAGLFGEDPHRPGRIHFAHAL
                     VQETLIDELAREDRQWLHARVAESLCARRPGHAGDAQTEQVAHHTWHAGSALPPAQALP
                     RLLRAAEQAEQQRAYERVETWLRRAVHLVGLLPHDDPSALPLERRLQIQLGQVLATTRG
                     YGHPEAETALAHGRALSAAAEAPEDPSVLWALCAAYLVTGRYDASRRFSGLLRGIAERT
                     GEPVAVLGAAYGEGIVLHIRGRLPQALAELEHGVGMADRYAREGHSLARTFQHDPRVSC
                     RSYNTFTHWLLGDRQTATARRRELLHLTACDSRPSDRSFALYVDAVVAAWEGDARTARS
                     SGAEGARLAGEHGLLYWKGMLGLLEGWGLTHSGWEDDGLALMHTSLAELRDSSTRLRHP
                     LHLGLLGEAQHHAGRSEEARATFRDLLSAVEARGEHVYLHEALPATRLLRDLLGSDAAG
                     AVARAAAAGAPRPAHPVARRAS"
     gene            6307..7137
                     /locus_tag="IE241_RS27905"
                     /old_locus_tag="GCM10010324_56990"
     CDS             6307..7137
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (29-222). E-value: 3.6e-44. Score:
                     142.6. Matches aSDomain:
                     nrpspksdomains_IE241_RS27905_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140915.1"
                     /locus_tag="IE241_RS27905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56990"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_229899907.1"
                     /sec_met_domain="PCMT (E-value: 1.1e-06, bitscore: 21.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAHTVFPVPEEVGRLYDRLTALDTAQTGGSLHLGYWEAEDDGV
                     PLAEAADRLTDMMTDRLRVDGSHRVLDVGCGVGQPAMRIARRTGAHVTGISVSRGQVAR
                     ATALAGAAGLSGRVEFRYADAMQLPFEDNSFDAVIAIESVFHMPDREQVFREIRRVLRP
                     GGRLVLTDFFERAPIAAGMRSVMDRCLRDFIMTLARPEDYVPMLSRAGLRFTELLDITE
                     QSVRRTFEQMSKARGDGGELRTAFDEAAVEKFGPADMVDVDEFGSVLLSAEKPL"
     aSDomain        6394..6972
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE241_RS27905_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.60E-44"
                     /label="IE241_RS27905_oMT.1"
                     /locus_tag="IE241_RS27905"
                     /protein_end="222"
                     /protein_start="29"
                     /score="142.6"
                     /tool="antismash"
                     /translation="GGSLHLGYWEAEDDGVPLAEAADRLTDMMTDRLRVDGSHRVLDVG
                     CGVGQPAMRIARRTGAHVTGISVSRGQVARATALAGAAGLSGRVEFRYADAMQLPFEDN
                     SFDAVIAIESVFHMPDREQVFREIRRVLRPGGRLVLTDFFERAPIAAGMRSVMDRCLRD
                     FIMTLARPEDYVPMLSRAGLRFTELLDITE"
     gene            complement(7211..8047)
                     /locus_tag="IE241_RS27910"
                     /old_locus_tag="GCM10010324_57000"
     CDS             complement(7211..8047)
                     /GO_function="GO:0015016 - [heparan sulfate]-glucosamine
                     N-sulfotransferase activity [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_1: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012888.5"
                     /locus_tag="IE241_RS27910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57000"
                     /product="sulfotransferase domain-containing protein"
                     /protein_id="WP_190024622.1"
                     /transl_table=11
                     /translation="MFPTPPPDKSVKAVDAHGDVYVISFPKCGRTWLRVLMAKAISAAH
                     HIPMEACRNLDLTGFSDVSPAVPRIVFWHDDRVLWRTPGELSRDKDFYHDRKVVLILRD
                     IRDTAVSCYFQQTRRQGRPYDAGLGAFLSEERGSVRTCLSFWNIWHARQHVPAGFLVTS
                     YERLTADTAGELSRILGFCGLPPAGDQALRAAVDFAGFDSMRAMELSDALGTDRLRPAV
                     PGDPDSYKTRRGVIGGFRDYLTGPQIDYVNDAVRRILAPAWHPAALAADTPLPQRP"
     misc_feature    8289..8305
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            8535..9965
                     /locus_tag="IE241_RS27915"
                     /old_locus_tag="GCM10010324_57010"
     CDS             8535..9965
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538392.1"
                     /locus_tag="IE241_RS27915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57010"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_190024623.1"
                     /transl_table=11
                     /translation="MSTAAHRQHQPEQPEQQAGRAQLSLGIAAARNLASTTKTAPQMQG
                     ISSRWLLRMLPWVEVKGGTYRVNRRLVYEVGDGRVTFVQEGAAVKVVPAELGELPLLRG
                     FHDDETLRALAERCRQQEYEPGQVIAERGRPVDHVYLIAHGKVEKAGAGRYGEETRRGV
                     LADGAYFGAQAVAEEPGTWEFTARAMTACTVLALPRYAYEEVAGRSERLRVHVRQRQAE
                     KARPQNKKGEANIALASGHAGEPVLPGTFVDYELAPREYELSVAQTILRVHSRVADLYN
                     DPMDQVEHQLRLTIEALRERQESELVNNPEFGLLHNADYSQRISTHSGPPTPDDMDELL
                     SMRRGTKAFFAHPRAVSAFARECNKRGLSFDSADLNGHPVPAWRGVPILPCGKIPVSEE
                     GTSSILAMRLGEGDQGVVGLRQTGIPDEYEPGLNVRFMGINDQALISYLVSTYYSAAVL
                     VPDALGVLENVEVFHTPS"
     gene            10001..11335
                     /locus_tag="IE241_RS27920"
                     /old_locus_tag="GCM10010324_57020"
     CDS             10001..11335
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890277.1"
                     /locus_tag="IE241_RS27920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57020"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_190024624.1"
                     /sec_met_domain="T1TS (E-value: 5.4e-62, bitscore: 203.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLSRITAPTARHDVARLVAALLTHHQGVRRSAPKALPGTTPRP
                     AGTRLPTGPTGLGTSAARIAAGKAAGKVAEKAAEKAAEKAAEKAAEKAAGKPVGGAPDV
                     SGASGISGAPGVSRGASGDRGTGVPELYCPPALRDDPALGQEVNDRLVAWADEVGIYDG
                     RLDRVRAADFGRLMMLAHPDSDDPDRLLAAGKCALAEWATDDYYCDDETMGSRTELLGS
                     HLGLAYTALDPSHLPARYAPTWEEEMREDPVRVALRSGLDHLSRYAEPSQVARLRHEVA
                     VLFVGYEQEGSWRSQGRMPGVREYLAHRQINSFLPCIALADVVGGYALPASVYAEPRVR
                     RAVTMAATAATLVNDLYSMTKEHDSSGVEFNLPVVIAEEDGCSLREAIERSAEIHDELV
                     HTYETEAAALALTGSPELRRFLAGVWAWLGGNREWHAGSPRYNSA"
     gene            11466..12332
                     /locus_tag="IE241_RS27925"
                     /old_locus_tag="GCM10010324_57030"
     CDS             11466..12332
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538391.1"
                     /locus_tag="IE241_RS27925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57030"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_190024625.1"
                     /transl_table=11
                     /translation="MTTTPAPEASAGVLRTAYQKSVAEYWNNEKDPVNLRLGDVDGLYH
                     HHYGLGDYDPSVLEGPEETRDARIIEELHRLESAQADVLLDHLGPIAPDQRVLDAGCGR
                     GGTSIMANARFGCRADGVSISRKQVDFANEQARKRGVDDKVRYHFANMLDTGLPTGAFQ
                     GIWNNESTMYVDLFELFAEHARQLAYGGRYVTITGCSNDVTGLRSKAVSRIDEHYTCNI
                     HPRSTYFKAMAANGLVPINVVDLTAATIPYWELRAQSSLATGVEDPFLTAYKEGSFHYL
                     LIAADRI"
     gene            complement(12424..13176)
                     /locus_tag="IE241_RS27930"
                     /old_locus_tag="GCM10010324_57040"
     CDS             complement(12424..13176)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643916.1"
                     /locus_tag="IE241_RS27930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57040"
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_190024626.1"
                     /transl_table=11
                     /translation="MTDDALFLDHVSDRLAALPAVRAVTLGGSRAQGTHTPDSDWDMAV
                     YYRGGFDPADLRAVGWEGEVSEIGGWGGGVFNGGAWLTIDGRTVDVHYRDLDVVDHELA
                     EARQGRFHWEPLMFHLAGIPSYLVVAELAVNQVLRGTLPRPEYPQALRETAPRMWRERA
                     ALTLRYAKGAYAGRGQATEVAGALATAALQTGHAVLAARGEWVTNEKRLLQQAGLRGID
                     AILSGLRPRPEALTRAIAEAEELFGTAD"
     misc_feature    complement(13382..13398)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.7"
                     /tool="antismash"
     gene            13463..>13708
                     /locus_tag="IE241_RS27935"
                     /old_locus_tag="GCM10010324_57050"
                     /pseudo=""
     CDS             13463..>13708
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950990.1"
                     /locus_tag="IE241_RS27935"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57050"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGTLLGSVVTHTFQRLASRRSELFTRSEALRQERIATYSAFAAAV
                     EDYRRGQADRWYRKREDPDGDAFVTARDEAHRLRTAA"
     gene            complement(13793..14593)
                     /locus_tag="IE241_RS27940"
                     /old_locus_tag="GCM10010324_57060"
     CDS             complement(13793..14593)
                     /EC_number="1.-.-.-"
                     /EC_number="1.6.99.-"
                     /GO_function="GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005318108.1"
                     /locus_tag="IE241_RS27940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57060"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_190024627.1"
                     /transl_table=11
                     /translation="MNDTAPQQHQQKKILLVTAHPEPRSLNASLAAFAAEHLRTAGHEV
                     QVSDLYAMKWKATVDADDFPDEAGDRRLEVMAASERATLAGRLSADVAAEQEKVRWSDA
                     VILQFPMWWFSMPAILKGWVDRVFTAGFGYGPALPPPYTGSALEGRRALVSVTAGARES
                     SFSDRGIHGRLADVLHPVQHGLFWFTGMAPLEPFVMYNANALPEERFEAAKREYGRRLD
                     GLFTDEPVPFRSLTGGDYDHDMRLLPGVETPGTSGLDLHIRPHN"
     gene            14691..15596
                     /locus_tag="IE241_RS27945"
                     /old_locus_tag="GCM10010324_57070"
     CDS             14691..15596
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088937.1"
                     /locus_tag="IE241_RS27945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57070"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_190024628.1"
                     /transl_table=11
                     /translation="MNGVDGSHIGGVGGVGDAQRALGGFLRARRGRVAPEQVGLAGAGG
                     RRRRVRGLRREELAQLAGISVDYYVRLEQGRATQPSAEVLDALAGALGLDAAERKHLDT
                     LAGARRDPMPRAEVSPLLQRVLDSLDRFPVFVTDHRMDVVAWNALGAELIGGAPGPGSR
                     DRNNARYLFLDPASRSVHPDWEARAAEAVGQLRVAAGRYPDDAELSALINELSAHSADF
                     RRIWGTGEVVMCAAGRKRLRHPVAGLLTLDFETLHVPAAPGETGLVVHVFSAGEGSEAA
                     AALAGLAGPGAAVVEAPGLR"
     gene            <15636..15989
                     /locus_tag="IE241_RS35040"
                     /old_locus_tag="GCM10010324_57080"
                     /pseudo=""
     CDS             <15636..15989
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024935.5"
                     /locus_tag="IE241_RS35040"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57080"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RPVELVGRLRSDRVLRLSKPPRGYDPRGGRPPKHGKEFGLARPES
                     WPEPSVPTVNDTPRYGKVEAEALAEVVLPGLDGGFFAMPGTGTPLSFSARAKVPVSGFE
                     SHAASGRGPAVTG"
     gene            complement(15979..16977)
                     /locus_tag="IE241_RS35045"
                     /old_locus_tag="GCM10010324_57090"
     CDS             complement(15979..16977)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045398.2"
                     /locus_tag="IE241_RS35045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57090"
                     /product="DUF4157 domain-containing protein"
                     /protein_id="WP_373300782.1"
                     /transl_table=11
                     /translation="MGLQGAVGNAAVVQMLRAAGHLGEEGEPRHAVHRRHGETGRPAVQ
                     RSAVHEVLRRPGRPLDDATRADMEARLGADFSDVRVHSGAAARASAAEIGARAYTSGSH
                     VVIGAGGGDKHTLAHELTQREETAVQRVNDSGNRPLISHANPNDDWFADNATAVRADGL
                     VLSGHGGWERVDGHFRVPRGTRLHFYTVHGQTVPDDLGGQVEQGNEQRGSVEQSRQPGA
                     SRTLAGGRSAPNYRISYPSGLTIRGNPVIATPVAGGYDVELDPATPAARVITVATLLDP
                     QLAGHSIVFDGDVLLSDILQTDMGDVHFAACRFVETGRPGTRNQKEGLFNP"
     gene            complement(17285..17698)
                     /locus_tag="IE241_RS27960"
                     /old_locus_tag="GCM10010324_57100"
     CDS             complement(17285..17698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823163.1"
                     /locus_tag="IE241_RS27960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57100"
                     /product="cytidine deaminase"
                     /protein_id="WP_190024630.1"
                     /transl_table=11
                     /translation="MTTQTHHVDHELVQAAAHVARTRCRGDNHTMAAAARARDGRIVTA
                     VNAYHFTGGPCAELVLIGAAAAQGAYELDTIVAVGDRDRGVVPPCGRCRQVLLDYFPAL
                     KVIVGEGDRVRTVPITDLLPESYVWADHQLDAE"
     gene            complement(17721..18065)
                     /locus_tag="IE241_RS27965"
                     /old_locus_tag="GCM10010324_57110"
     CDS             complement(17721..18065)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS27965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_57110"
                     /product="hypothetical protein"
                     /protein_id="WP_190024631.1"
                     /transl_table=11
                     /translation="MTGHALKAGGAGELVRAAAMDVYYLPGNGPGRCNLLRIRQHDGLF
                     QRELRRRGKSIQTSARSSHWLGTFNRSSRGLLRAAQLDHRGIEADLEPWRNKHTADIRL
                     RTLVTWVNVA"
     misc_feature    complement(17838..17840)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18118..19698)
                     /locus_tag="IE241_RS27970"
                     /old_locus_tag="GCM10010324_57120"
     CDS             complement(18118..19698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959469.1"
                     /locus_tag="IE241_RS27970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57120"
                     /product="serine protease"
                     /protein_id="WP_190024632.1"
                     /transl_table=11
                     /translation="MTTSSVPRRSVLRTLAVAVALVGSATPAWDATAFAAEPETYSLTI
                     KHLDRGGRSTGDYATTVTGISGPGADKSVQPHDASGTTTVRLPKGRYVLDSYLTTGNAA
                     GGTDGTDWIVQPRLDLDRDTTVTVDARTTAPVDVRPPDGSAEFLHSMMVVEVKHGGTTR
                     LLNRMAAKPNLRVAHLGPDAEPGSVKQWFDAYWTTKSADYALGYVFTGPRALTGLTRHP
                     SAKDLAALQIRGAARPGTTGAGPASIDLQPSSGVTLGVSQRLASPGDATYFVTPERGTW
                     DVTYWPPAAPGGASNRYTANGIAVRAGSTTTHTFDNAVFGPALPDRPGVVRDGDRLTVD
                     VPMLADGDGHVPSSPSYASASTTLHRDGVLVGTKSGAPGRAGFTVPAGDASYRLTSTVK
                     RNGAPGTATQVTSAWTFASRTTTGPVPVPVSAVRFSPELSPTGTAAANTALRVPVTVQG
                     AAANGRVRSLTISMSVDGGASWTRIPVESGAVTIRNPRAGTGVTLRAELTDTDGNTLTQ
                     TIVDAYRTQ"
     gene            19843..20568
                     /locus_tag="IE241_RS27975"
                     /old_locus_tag="GCM10010324_57130"
     CDS             19843..20568
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961137.1"
                     /locus_tag="IE241_RS27975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_57130"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_229899909.1"
                     /transl_table=11
                     /translation="MRNRFRRGDRDALAELYDEHAQVLYRYALRVTGDWAEAEDVVSAS
                     FLEAWRGRERVRPDGDSLRPWLLGIATNIMRRNARARRLRDIALARVPERGSIPDFADD
                     LVTHMADTEQLRAAHAALARLRRRDREVFTLVVWAGLDYAAAAEALGVPVGTVRSRLSR
                     ARTRLRELADAEARTARSQASRFSRSSRDVAERPRAADSGGFSGGVLEEAPGEVSATPD
                     MPVAGRIPLARPLTQENHG"
ORIGIN
        1 cgggctgatc ctggtccagc tgcacggccg ggagcagagg caggtcgcag cggccgagcg
       61 cctggcaggg aagtggaccg gctgctccgg gccgctgcgg gtgaccgctg ccggcgcggc
      121 gatggtccgc gtggagttcc aacggcaggc cgaacgggac caggagcggg ccgaggtgtt
      181 cgtcgttccc ctggtggccc tgctgttgct gttcggcttc cgctccgccg tggccgcggc
      241 cctcccgctg gtcatcggcg tggtgtccgt catcgcgacg tcggccgtga tgcgcgcgct
      301 gtgcgcctcc atgcagatgt cggtgtacgc ctggaacatc gccgtcgccc tgggcttcgg
      361 cctggcggtg gactacagcc tgttcctggt cagccggtac cgcgaggagc tggcgcaggg
      421 cgcccccgtg cccggggccg tacggacggc gatgcgcacg gcgggcagga cggtggcgtt
      481 ctcggcgggc gtggtcggct tgccgatggc cgccctgctg ctggtgccga tccccgtgct
      541 ccgctccatc gccgccggcg gtctggcggc tgcggcgctc accgccgcca ccacgttgct
      601 gatcctgccc gcgctgctga cggtgctggg cgagcgggtg caccggttcg acgtcttcgg
      661 ccgctggcgg cggcgtccgc gtcccggcgg cgacgggcgt ggcgagctgt cccgctgggg
      721 acggtgcgca gcagcggtga tgcggcaccc gctgcggttc gccgtgcccg tcctggtgct
      781 cctcgccgtc ttcgtcgccc ctctctcagg ggtgcggttc gggctgttcg acgaccggtc
      841 gatgcccgcg ggctcggcga tcgcccgggc gtccgccacc ctgcgcgccg actaccccgc
      901 gtacgaggcg gtcagcaaca cgaccgtcgc gctgcccggc ctggatccgg tcacgcgcaa
      961 ggccgacctc gaccgctacg cgcaccggat ctccgggctg gacggagtgc tgcaggtgcg
     1021 gaccgccgac ggcgtccatg tgcacggggg accgttcctg cagagccgcc gggagagcgc
     1081 cgtgttcggc aacgcccacg gcacctggct cagcgtctcc accgccgacc ggagccccgg
     1141 ccccgagagc ggcgcgctgg cccggcgggt gcgtgccctg ccctcacccg tccccgccct
     1201 ggtgagcggc cccggggccc ggctcgccga cgtccaacag gccatcggcc accggctgcc
     1261 ctacgtcctg gccctggtcg tgctcgccat caccactctc atcctggcgc tgacccgcca
     1321 cccggtgctc gtcctcaaag ccctcgtcct caacgtgctg agcatggccg ccgccttcgg
     1381 cgcgctggtc cacatcttcc agcgaggcca cctccgcttc ctcgtcggcg acttcacggc
     1441 cacgggcacc ttcgacgccc tgcagccgat cctggtgttc tgcgtcgtct tcgggctgtc
     1501 catggactac gaactgttcc tgctgtcccg gatcgtggag gagtaccgga acaccgggtc
     1561 caccagagag gccgtcgtac ggggcatgga ccgcaccgcc tccctgttca ccctggccgc
     1621 agcgaccctg gccgtggtca cctccgccct ggcgacctcc gacctggtcg tcctgaagtt
     1681 cgccggagtc gggaccgccc tggccgtcct cctggacgcc accgtcatcc gcggcctgct
     1741 cctgcccgcc gtcatgcagc tggtgggccg ggcgaactgg tggacgcccg cgctcctccg
     1801 gcggcgcgag ccgaaagccg gcacggccgg cccggtggac cccaccaccg cgtaacgtaa
     1861 cctcgcccgt caggggtcca tgacacgcaa ggaggcagcc gcgtgaaggg gacattcgag
     1921 gcggtcaccg gggacgcatg cccgcccgcg gggaacgctt ccgagcgagc gtccgcggtg
     1981 cgcgaggcga tggaagggct gctgcagatc cggcggctga tgaacggtca cctcacggag
     2041 ccgttgtccg gccccgccga ctgggagcgg cgtcagcccg tgcgcgccgt cgccctcatc
     2101 ctcgaagccg cgggcatccc tccctccgcc ctcgacgccg aggggcggcg ttgtgcgacc
     2161 ggctactgcg tccgtcccgg cgagcagccg gggaccgtac gggtcgaatg gctcggcccg
     2221 cccggcagcg gggcggccgc tcgacagcac gaggcccttc agcggtgcgc ccgcgccctg
     2281 gaggacgcgg ggtggccggc gctggagtat cgcggggcac gcaagcagcg ctggctggaa
     2341 gccgagcccc tcgttcagcg ggggcgctag gaggcccgcc gggcgacggg atgcgcggga
     2401 cgcggcgccc ccgccgcggc cgccctcgcc accgcccccg ccgcatcgct ccccagcagg
     2461 tcgcggagca gccgcgtggc gggcagggcc tcgtgcagat agacgtgctc gccgcgcgcc
     2521 tcgaccgccg agagcaggtc gcggaaggtc gccctcgcct cctcggaccg cccggcgtgg
     2581 tgctgggcct cgccgagcag gcccaggtgg agggggtggc gcaagcgcgt gctggagtcg
     2641 cgcagttcgg ccagggaggt gtgcatcagg gcgaggccgt cgtcctccca ccccgagtgc
     2701 gtcagacccc acccttcgag caggcccagc atccccttcc agtacaggag cccgtgttcg
     2761 cccgccaggc gggcaccctc ggcgccggag gaccgcgccg tgcgggcgtc gccctcccag
     2821 gccgccacga ccgcgtccac gtagagggcg aaggaccggt cggagggcct gctgtcgcat
     2881 gcggtcaggt gcagcagctc gcgccggcgc gccgtggcgg tctgccggtc gccgaggagc
     2941 cagtgggtga acgtgttgta cgagcggcag gagacacgcg ggtcgtgctg gaaggtgcgg
     3001 gccagcgagt ggccttcacg ggcgtagcgg tccgccatgc cgaccccgtg ctccagttcg
     3061 gcgagcgcct gcggcagccg gccgcggatg tgcagcacga tgccctcgcc gtacgccgcg
     3121 ccgagcaccg ccacgggctc accggtccgt tccgcgatgc cccgcagcag gccggagaag
     3181 cgccgcgagg cgtcgtagcg gccggtcacc aggtacgccg cgcacagcgc ccagagcacc
     3241 gacgggtcct cgggcgcctc ggcggccgcg ctgagcgccc ggccgtgcgc gagcgccgtc
     3301 tcggcctcgg ggtggccgta gccgcgggtc gtggccagca cctggccgag ctggatctgc
     3361 agccgccgct ccaggggcag ggccgaggga tcgtcgtggg gcagcaggcc gacgaggtgc
     3421 accgcccggc gcagccaggt ctccacgcgc tcgtacgccc gctgctgctc ggcctgctcg
     3481 gccgcgcgca gcagccgggg gagcgcctgc gcagggggca gcgcgctccc ggcgtgccag
     3541 gtgtggtgag ccacctgctc ggtctgcgcg tcccccgcgt gcccgggcct gcgggcgcac
     3601 agcgactcgg cgaccctggc gtgcagccac tgccggtcct cgcgcgcgag ctcgtcgatg
     3661 agcgtctcct ggaccagggc gtgggcgaag tggatccgcc ccggacggtg cgggtcctcg
     3721 ccgaacagcc cggcgcggat cgccgactcc agcgcctcgg cgaccggttc gtccgcggcg
     3781 gccgtgcggt gcagcaggtc ggtgtcgacc tcggagccga tgacggcgca cagccgcagc
     3841 acctgcagca ccggttcggg cagcgcggcg aaccgctggt gcagcacctc gcgcacaccc
     3901 gtcggaacgc gggtcagcag cacgtccacc gcgtcggggc ggcgcaggct gccgggatcc
     3961 cccaggaggg acaggagctg catgacgaag tacggattgc cctcactgcg ccggtgcagc
     4021 acctcgacga ccttcgcgtc cacccccggg ccggcctgcg ccacgacgat cgcggcgacg
     4081 gactgccggg agagcccgcc gagccgcagg gtctcggtcc tcgggccgcg caggacctcg
     4141 gagagcatcc ggcgcatcgt ggcgtccgac tcgacctcga actcgcgggc cgtcagcacg
     4201 atgcccagcg ggtggccctg gcggcgggtg ctcagcagcc ggagcaggtc cagcgaggcg
     4261 gtgtcggccc agtgcaggtc ctccaggaac agcacgagcg gacgctgccc ggccagggtg
     4321 agcaggactt cgcagaccgc gtcgtgggtc aggaaacggg cctgccccca gtcggaaccg
     4381 gcgcccggcc cgctcccgcc ggggcaggcc gaccgctcgg gcatgagggg ggcgaggagg
     4441 gagccgaaag gttccgtcgc gcggcggaag gcgtccgggc gggtgacgga cagccgccgg
     4501 agcacctgcg tccacaacca gtagggcggt acgccctcgc tcaggaaaca gtggctccag
     4561 acgacctcca gacgcgcgcc gccctggctc gcacaggcgg cttccaaccg cggggcgagt
     4621 tcgaggagca gacgggtctt gccgaccccg gcggggccga ggacaccggc cacgtggccg
     4681 tgcccggcca gcgcgctcgc cgtcgcggtc gtcagccgct gcagctcctc gctgcgcccg
     4741 gtgaacggcg actggccgat cggctgcccg ggctcggcgg tgtcgccggt gtcgcccatg
     4801 ccgcgcgtat cgcctgcgcc gtccgtgtcg gctgtggcac ccgtgccggc cgtggcagcc
     4861 gtacgaggtg cttcggctgt tccgttggcg tcggcgtcgg cgtcggcgtc cgcgtccgcg
     4921 tcggcggctc cggccgtgcc gctctgctca cctgaggtgt tcggcgcgac ctcgtggacg
     4981 acgtgaacga cgtggtcggc cggggcggtc tcgccggccg ctgcggttgc gccggcctgg
     5041 tggaggatcg ccgtcctgac gcggcggagt gcggcggtgg tgcccacccc gaactcctcg
     5101 gccaggtggc tgcgcgtccg ttcgtagacc gcgagagcct cggcctgccg gccgagccgg
     5161 gacagagcgg tcatcaggtg gccgacgagc cgttcccgcg ccggatggcg gcgcacctcc
     5221 cggtcgaggt ccccggccac ctcctcggcc gctccgaggg ccaggcgggc ctccgcgcag
     5281 gactccacgg ccgtgagccg caggtgttcc agccgcgcgc tctcgtcgct gagcggcggg
     5341 tggccgtcga actccccgta gggcgtgccc cgccacagct ccagcgcctc ggtcaaccgg
     5401 tcccgtgcgg ccgccggatc gcgctgttcc agcagcctcc gcccctcggt gaccaggagc
     5461 tcgaagcggc aggcgtcgat ccgtgcgggg tcgagctcca ggacgtagcc gcccgcccgg
     5521 tggcgcagca ccggcacacc gtccggcccg gccgccggct ggagggcacg gcgcaggtgg
     5581 gagacgtggc tctggagcgt ggcgacggcg cggcgcggcg gttcctcgcc ccacagctcc
     5641 tcgacgagca gttccatggg cacgacgcga ccgaggcgta tgaggagcag tgcgagcagc
     5701 gcccgtcggc ggggcggccc gatcggcagg tcatgcccgt cgtggcgcgc cgtcatgggg
     5761 cccaggacgc tcagcagggg ctcgatcggg gcggtggccg ccggccgggc cgccgaatga
     5821 gccgccggcc gggccgctga gtgagtcgcc ggccgggctg ccggtgccgg agccggtgcc
     5881 ggatccggcg tcggggatgc gggcatgtgg ctcccaatcg ttctcgtacg cgcgactgat
     5941 gtcggtcgtc cggcgcagag acgcaggcgc cttccaaaac ggatcttggc atacgcacca
     6001 gggcattcca agatcgcgac aagccatcgg caagtgaacg gcaagggaac cgcaaggact
     6061 tcgccagggc ggccggaacc ggcggcaggc gacggcaagg aaacgtcagt ggcgcggcca
     6121 ggccgctgca aggacggtgc tgcacgatgt ccgtcgccgg aggagaccgc cgctgccggg
     6181 aagcgcggga agcgcggaaa cgcatgaacg cgacgggatc cctcacgccg acgggggtga
     6241 cgtgagggaa tctctcgatt ccgctggttc aacagacatg tctcagaaga aagcggagga
     6301 tcttccgtgt ccagcgctca caccgtcttc cccgtccccg aagaagtcgg acgcctctac
     6361 gaccgcctga ccgcgctcga caccgcgcag accggcggaa gcctccacct cggctactgg
     6421 gaggccgagg acgacggtgt gccgctcgcg gaggccgccg accggctcac cgacatgatg
     6481 acggaccgcc tgcgggtcga cgggagccat cgcgtgctcg acgtcggctg cggagtcggg
     6541 cagccggcca tgcgaatcgc ccggcgcacc ggcgcgcacg tcaccggcat ctccgtcagc
     6601 cgcgggcagg tcgcgcgcgc cacggcgctc gccggggcgg cggggctgag cggccgcgtg
     6661 gagttccgct acgccgacgc catgcaactc cccttcgagg acaactcgtt cgacgccgtc
     6721 atcgccatcg agtcggtctt ccacatgccc gaccgcgagc aggtgttccg cgagatccgg
     6781 cgggtgctgc gccccggcgg ccggctggtg ctgaccgact tcttcgagcg ggctccgatc
     6841 gcggccggaa tgcggtccgt catggaccgg tgcctccggg acttcatcat gaccctggcg
     6901 cggcccgagg actacgtgcc catgctgagc cgcgcggggc tgcgcttcac cgaactcctc
     6961 gacatcaccg agcagagtgt gcgccggacc ttcgagcaga tgagcaaggc ccgcggggac
     7021 gggggagagc tgcggaccgc gttcgacgaa gcggcggtgg agaagttcgg ccccgccgac
     7081 atggtcgacg tcgacgagtt cggctccgtc ctgctgtccg cggagaagcc cctctgacgg
     7141 gaccggacac gacgcggatg ggcgtgggtg aggtgaggca aggcgagcag gcacgcgatc
     7201 aggtgcgcga tcaaggcctc tgggggagtg gtgtgtccgc agcgagggct gccgggtgcc
     7261 atgcgggcgc gaggatccgg cggacggcgt cgttgacgta gtcgatctgc gggccggtga
     7321 gatagtcgcg gaatccgccg atgacgccgc ggcgcgtctt gtacgagtcg gggtcgccgg
     7381 gcacggcggg ccggagccgg tccgtgccca gcgcgtcgga gagctccatg gcgcgcatgg
     7441 agtcgaagcc cgcgaagtcc accgcggccc gcagcgcctg gtcaccggcc ggcggcaggc
     7501 cgcagaagcc gagtatgcgg gagagttctc cggcggtgtc ggcggtgagc cgctcgtagg
     7561 aggtgacgag gaagccggcg ggcacgtgct gccgggcgtg ccagatgttc cagaaggaca
     7621 ggcaggtcct gacgctgccc cgctcctcgg acaggaaggc tccgagcccg gcgtcgtagg
     7681 gccggccctg ccggcgggtc tgctggaagt agcaggagac ggcggtgtcc cggatgtcgc
     7741 ggaggatgag gaccaccttg cggtcgtggt agaagtcctt gtcccgggac agctcgccgg
     7801 gggtccgcca caggacgcgg tcgtcgtgcc agaagacgat gcgcggaacg gccggtgaca
     7861 cgtcgctgaa cccggtcagg tccaggttcc tgcaggcctc catggggatg tgatgcgcgg
     7921 ccgagatggc cttggccatc aggacccgca gccacgtccg gccgcacttc gggaacgaga
     7981 tgacgtagac gtcaccgtgc gcgtcgacgg ccttcacgct cttgtccggg ggcggagtcg
     8041 ggaacatggg actcccttcg gcggcggtgc ccggggctgg acccaggcgg ccacgatccc
     8101 ggatcaccgg ccctccggca acagggcgtc agggcatcga ggtatggggg catcggggtg
     8161 ccggggaacg ccggtcggca cgtactgccg cggcggactg acgcaatgtc atgccgcaag
     8221 aggcccgacc gcacactatc ggccacctcg cccatggggt cggggctctc cggctcaccg
     8281 gcccgcggtg atgaaaatgc ggacattccc accacatcgt gagtgatggc cgcccctggg
     8341 cgcacgacaa gctcggtgta tgccgcacga accatcgccc tctcatggcg caaaggtgac
     8401 ggtgcagcct cggccatctc gaccaacatc atcaagcgct gcttcacttg cgcggcggga
     8461 gcccccagtc gcccgatcgg gctattgcaa gggctccctc ttgacgcatg cgcccagatg
     8521 gaagagggac cgggatgtcg accgcagcgc accggcagca ccagccggag cagcccgaac
     8581 agcaagcagg ccgggcccag ctcagcctgg ggatcgccgc tgcgcggaac ctggcgagta
     8641 ccaccaagac cgccccgcag atgcagggca tcagctcgcg ctggctgctg cgcatgctgc
     8701 cgtgggtgga ggtgaagggc ggcacgtacc gggtcaaccg gcgcctggtg tacgaggtcg
     8761 gcgacggccg cgtcaccttc gtccaggaag gcgccgcggt caaggtcgtc cccgcggagc
     8821 tgggggaact gccgctgctg cgcggattcc acgacgacga gacgctgcgc gcgctggccg
     8881 agcggtgccg gcagcaggag tacgaacccg gccaggtgat cgccgaacgg ggccggcccg
     8941 tcgaccacgt ctatctgatc gcgcacggca aggtggagaa ggccggagcc gggaggtacg
     9001 gcgaggagac ccgtcgcggc gtgctggccg acggcgcgta cttcggcgcg caggcggtgg
     9061 ccgaggagcc gggcacctgg gagttcacgg cccgcgcgat gacggcgtgc accgtcctgg
     9121 ccctgccccg gtacgcctac gaggaggtgg cgggccgcag cgagcggctg cgggtccacg
     9181 tccggcagcg tcaggccgaa aaggcgcgtc cgcagaacaa gaagggcgag gcgaacatcg
     9241 ccctcgcctc cggccacgcc ggtgagccgg tgctgccggg caccttcgtc gactacgagc
     9301 tcgccccccg cgagtacgag ctgagcgtgg cgcagacgat cctgcgggtc cacagcaggg
     9361 tcgccgacct ctacaacgac ccgatggacc aggtcgagca ccagctgcgg ctgaccatcg
     9421 aggcgctgcg cgagcgccag gagtccgagc tcgtcaacaa ccccgagttc ggcctgctgc
     9481 acaacgccga ctacagccag cgcatctcca cccactccgg cccgcccacg cccgacgaca
     9541 tggacgagct gttgagcatg cggcgcggga ccaaggcgtt cttcgcccac ccccgggccg
     9601 tctccgcctt cgcccgcgag tgcaacaagc ggggcctgtc cttcgacagc gccgacctga
     9661 acggccaccc cgtgcccgcc tggcggggcg tcccgatcct gccctgcggc aagatccccg
     9721 tctcggagga gggcacctcc tccatcctcg ccatgcgcct gggcgagggc gaccagggag
     9781 tcgtcggcct gcggcagacc gggatccccg acgagtacga gcccggcctg aacgtgcggt
     9841 tcatgggcat caacgaccag gccctcatct cctacctggt cagcacctac tactcggcgg
     9901 ccgttctcgt ccccgacgcg ctcggcgtcc tggagaacgt cgaggtcttc cacaccccgt
     9961 cctgacgggc accacccccc cggaacggag agaagaacct gtgtcactgc tgtccaggat
    10021 caccgcgccc acggcccgcc acgacgtggc gcggctggtg gccgcgctgc tcacccatca
    10081 ccagggcgtc cggcgttccg caccgaaggc gctgcccgga accacgcccc gcccggcggg
    10141 cacccgcctg cccaccgggc ccacggggct gggcacctcc gccgcccgca tcgcggccgg
    10201 gaaggctgca gggaaagtcg cagagaaagc agcagagaag gcagcagaga aggcagcaga
    10261 gaaggcagca gagaaggccg cagggaagcc ggtgggtggc gcccctgacg tctccggtgc
    10321 ctctggtatc tccggtgccc ccggcgtctc ccgcggcgcc tcgggtgacc gcggcaccgg
    10381 ggtcccggag ctgtactgcc cgcccgcgct ccgcgacgac ccggcgctgg gccaggaggt
    10441 caacgaccgg ctggtggcct gggcggacga ggtcggcata tacgacggac ggctggatcg
    10501 cgtccgggcg gccgacttcg ggcgcctgat gatgctggcc caccccgaca gcgacgaccc
    10561 ggaccggctg ctggcggcgg ggaagtgcgc cctggccgag tgggccacgg acgactacta
    10621 ctgcgatgac gagaccatgg gctccaggac cgaactcctc ggctcccacc tcggactcgc
    10681 ctacacggcc ctcgacccct cccacctccc ggcccgctac gcgccgacct gggaggagga
    10741 gatgcgcgag gaccccgtac gggtcgccct gcgctcgggc ctggaccacc tgtcccgcta
    10801 cgcggagccc tcgcaggtcg cccggctgcg gcacgaggtc gccgtcctct tcgtgggcta
    10861 cgagcaggag ggttcgtggc gctcccaggg ccgcatgccc ggcgtccgcg aatacctggc
    10921 ccaccgtcag atcaacagct tcctcccctg catcgcactc gccgacgtgg tcggcggcta
    10981 cgcgctgccc gcctccgtat acgccgaacc gcgcgtgcgc cgcgccgtga cgatggccgc
    11041 cacggccgcc acgctcgtca acgacctgta ctcgatgacg aaggaacacg actcctcggg
    11101 cgtggagttc aacctccccg tcgtgatcgc cgaggaggac ggctgctcgc tgcgcgaggc
    11161 catcgagcgg agtgcggaga tccacgacga gctcgtgcac acctacgaga cggaggccgc
    11221 ggccctcgcc ctcaccggat cgcccgagct gcgccggttc ctcgcgggag tctgggcctg
    11281 gctcggcggc aaccgcgaat ggcacgccgg gagcccccgc tacaacagcg cgtgagcctg
    11341 ccctgcttcg cgtccgtccc ctctgttcct tgaacaccca cgcacatcac gcacatcacg
    11401 cacatcacgt acgccacgca caccgcgcgt actcacgcat gccctgatcc gtaaggagca
    11461 ccaccatgac gaccacgcct gcccccgaag cgtccgccgg cgtcctgcgc accgcctacc
    11521 agaagtcggt cgcggagtac tggaacaacg agaaggaccc ggtcaacctg cgcctgggcg
    11581 acgtcgacgg cctctaccac caccactacg gcctcggcga ctacgacccg tccgtcctgg
    11641 agggccccga ggagacccgg gacgcgcgca tcatcgagga gctgcaccgc ctggagtcgg
    11701 cgcaggccga cgtcctcctc gaccacctcg gccccatcgc ccccgaccag cgcgtgctgg
    11761 acgccggctg cggccgcggc ggcaccagca tcatggccaa cgcccgcttc ggctgccggg
    11821 ccgacggcgt ctccatctcc cggaagcagg tcgacttcgc caacgagcag gcccgcaagc
    11881 ggggcgtgga cgacaaggtc cgctaccact tcgccaacat gctggacacc ggcctgccca
    11941 ccggcgcctt ccagggcatc tggaacaacg agtccaccat gtacgtcgac ctgttcgagc
    12001 tcttcgccga gcacgcccgc cagctggcgt acggcggccg ctacgtcacc atcaccggct
    12061 gctccaacga cgtgacgggc ctgcgatcca aggccgtcag ccgcatcgac gagcactaca
    12121 cgtgcaacat ccacccccgc agcacgtact tcaaggccat ggccgccaac ggcctcgtgc
    12181 ccatcaacgt cgtcgacctc acggccgcga ccatcccgta ctgggagctg cgcgcccagt
    12241 cctccctcgc caccggcgtc gaggacccct tcctgaccgc gtacaaggag ggcagcttcc
    12301 actacctcct gatcgccgcc gaccgcatct gacccacggg cggcgggacc ccggcccggt
    12361 cccgccgccg cagcccggcg gagtgcaggg tgagaacaga gccgagggtg gccttcggca
    12421 gcctcagtcg gcggttccga acagctcctc ggcctcggcg atcgccctgg tcagggcctc
    12481 gggccgcgga cggagcccgg acaggatcgc gtcgatgccc cgcagaccgg cctgctgcag
    12541 gagccgcttc tcgttggtga cccactcgcc gcgcgccgcc agcaccgcgt gccccgtctg
    12601 cagggcggcg gtggccagcg cgcccgcgac ctccgtggcc tggccgcgcc cggcgtacgc
    12661 gcccttggcg tagcggagcg tcagggccgc gcgctcccgc cacatccgcg gggccgtctc
    12721 gcgcagggcc tgcgggtact cggggcgcgg cagggtgccg cgcagcacct ggttgacggc
    12781 gagctcggcg accaccaggt agctcgggat gcccgcgagg tggaacatca ggggctccca
    12841 gtggaagcgg ccctgccggg cctcggcgag ttcgtggtcc acgacgtcga ggtcgcggta
    12901 gtggacgtcg acggtccggc cgtcgatcgt gagccaggcc ccgccgttga acacgccgcc
    12961 gccccagcca ccgatctcgg agacctcgcc ctcccagccg acggcacgca gatccgccgg
    13021 gtcgaaaccg ccgcggtagt acacggccat gtcccagtcg ctgtcggggg tgtgggtgcc
    13081 ttgagcgcgc gagccgccga gggtgacggc gcgtacggcg ggcagcgccg cgagccggtc
    13141 ggagacgtgg tcgaggaaga gtgcgtcgtc ggtcatgagg atccgatcgt gagaagccgc
    13201 gggaaatcgc gagaagtgga tgacgttgtg agccatgagg gcgatgcggg cacaccgggg
    13261 gaacgccgga gcggctgggc tcggacggcg ttccgtggat cggtgtgcgg gcgtgtcatc
    13321 acttcatgaa gcagactcta tcgacgagat acccggcgcg ctcggccggc ctgcccgtga
    13381 ctgccggttg taccagcacc tcttgcactt cttgtgatcg actggcgctg tggaagctat
    13441 ctggacaagt gtcgtagcgg tgatgggcac gctgctgggt tccgtggtca cgcacacctt
    13501 ccagcgcctc gcctccaggc gcagtgagct gttcacacgc tccgaggcgc ttcggcagga
    13561 acgtatagcc acgtacagtg cgttcgccgc agcggtggag gactaccgcc gtggccaggc
    13621 ggaccgctgg taccgcaagc gagaggatcc ggacggggac gcgttcgtca cggcgcggga
    13681 cgaggcacac cggctccgga cagcggcctt tgtctcccgc gcttcgctgc tggtgcggtg
    13741 agcggagggc gtccgctcac tctgctcact ccgcgcggtc agcagtccgc actcagttgt
    13801 gcgggcggat gtgcaggtcg agcccgctgg tgcccggcgt ctccacgccc ggcaggagcc
    13861 gcatgtcgtg gtcgtaatcg ccgcccgtga gcgaccggaa cggaaccggc tcgtccgtga
    13921 agagcccgtc gagccggcgc ccgtactccc gcttcgccgc ctcgaaccgc tcctccggca
    13981 gggcgttcgc gttgtacatc acgaacggtt cgagcggcgc catgccggtg aaccagaaca
    14041 ggccgtgctg caccgggtgg aggacgtccg ccagccgtcc gtgaatgccc cggtcggaga
    14101 acgacgactc ccgggcgccg gccgtcaccg acaccagcgc ccgccgtccc tccagggcgc
    14161 tcccggtgta gggcggaggg agggccgggc cgtagccgaa cccggcggtg aacacccggt
    14221 cgacccagcc cttgagtatc gcgggcatgg agaaccacca catcgggaac tgcaggatca
    14281 ccgcgtccga ccagcgcacc ttctcctgct cggccgcgac gtcggcggac agccggcccg
    14341 ccagcgtggc ccgctcggag gcggccatca cctccagccg acggtccccc gcttcgtccg
    14401 ggaagtcgtc cgcgtcgacc gtcgccttcc acttcatcgc gtagaggtcg gagacctgca
    14461 cctcgtgtcc tgccgtgcgc aggtgctcgg ccgcgaaggc ggccagggag gcgttgagcg
    14521 agcggggctc ggggtgggcg gtgacgagga ggatcttctt ctgctggtgc tgctgcggtg
    14581 cggtgtcgtt catgcagcta cggtctcccg agcgcacccg ggtagccagc accctgtttt
    14641 acctgcggat ccgtgatcct ggtactgcca gggccaccat actggagcgt atgaacggcg
    14701 tggacggcag tcacatcgga ggagtcggcg gggtcggcga tgcccagcgg gcgctcggcg
    14761 gatttctgcg cgcccgccgc gggcgggtgg caccggagca ggtcgggctg gccggcgccg
    14821 gcggtcgccg tcggcgcgtg cgcgggctgc gccgcgagga gctggctcag ctcgccggca
    14881 tcagcgtgga ctactacgtc cgcctggagc agggccgcgc cacccagccg tccgcggagg
    14941 tgctcgacgc gctcgcgggg gcgctgggcc tggacgcggc ggagcgcaaa cacctggaca
    15001 cgctcgccgg cgccaggcgc gaccccatgc ccagggcgga ggtcagcccc ctcctgcagc
    15061 gggtgctgga ttccctggac cgcttcccgg tgttcgtgac ggaccaccgc atggacgtgg
    15121 tggcctggaa cgccctgggt gccgagctga tcggcggcgc gcccgggccg gggagccgcg
    15181 accggaacaa cgccaggtac ctcttcctcg acccggcctc ccggtccgtc caccccgact
    15241 gggaggccag ggcggcggag gccgtgggcc agctgcgggt cgccgcgggg cgttaccccg
    15301 acgatgcgga actgtccgcc ctcatcaacg aactgtccgc gcacagcgcc gacttccgga
    15361 ggatctgggg caccggcgag gtcgtgatgt gcgcagcggg ccgcaagcgc ctgcggcacc
    15421 cggtggccgg gctgctcacc ctggacttcg agacgctgca cgtgccggcc gcgcccgggg
    15481 agacggggtt ggtggtgcac gtgttcagcg cgggggaggg cagtgaggcg gcggcggccc
    15541 tcgccggcct cgccgggccg ggcgcggccg tagtggaggc gcctggtctg cgctgagctc
    15601 caccggcacc ggcaccgagg ccagggaatc gcgaccgtcc cgtcgagctg gtcggacgcc
    15661 tgcgctcgga ccgcgtgctg aggctgtcga agccgccgcg cggctacgat cccaggggtg
    15721 gccggccgcc gaagcacggc aaggagttcg gccttgccag gcccgagtca tggccggagc
    15781 cctctgtgcc gacggtcaac gacacccccc gatacggcaa ggtcgaagcc gaggcgctcg
    15841 cggaggtcgt tcttcccggt ctggatggtg ggttcttcgc gatgcccggg acggggacgc
    15901 ccttgtcctt cagtgcgagg gcaaaggtgc cggtgagcgg ttttgagagt cacgcagcgt
    15961 cgggccgtgg tcccgccgtc acgggttgaa gagcccctcc ttctggttcc tcgtgcccgg
    16021 gcggccggtc tccacgaagc ggcaggccgc gaagtgcacg tcgcccatgt ccgtctgaag
    16081 gatgtcgctc agcagcacat cgccgtcgaa cacgatcgag tgccccgcga gttgggggtc
    16141 gaggagcgtg gccacggtga tgactctggc ggccggggtt gccgggtcga gttcgacgtc
    16201 gtacccgccc gccacgggtg tggcaatcac ggggttgccc ctgatggtga gcccggaggg
    16261 gtaggagatc cggtagttgg gagcggatcg gccgcccgcc agggtgcgcg aggcgccggg
    16321 ctgccggctc tgctcgacgc tgccgcgctg ctcgttgccc tgctccacct ggccgcccag
    16381 gtcgtccggg acggtctgcc cgtggacggt gtagaagtgc agcctcgtgc ccctgggcac
    16441 ccggaagtgg ccgtccaccc gctcccagcc gccgtgaccg ctcaggacga ggccatccgc
    16501 gcgcacggcg gtggcgttgt cggcgaacca gtcgtcgttc gggttggcgt ggctgatcag
    16561 gggccggttt cccgagtcgt tcacgcgctg gactgcggtt tcctcgcgct gggtcagctc
    16621 gtgcgcgagc gtgtgcttgt ctccgccccc ggcgccgatg accacatggc tgcccgaggt
    16681 gtacgcgcgt gccccgatct ctgcggcgga ggccctcgcc gcggcgccgc tgtgcacccg
    16741 tacgtccgag aagtcggcgc cgagccgcgc ctccatgtcg gcgcgggtcg cgtcgtcgag
    16801 cggccgccct ggcctgcgga ggacctcgtg caccgcggaa cgttgcacgg cgggtcgccc
    16861 ggtttcgccg tgccgacgat ggacggcgtg ccggggttcg ccctcctccc cgaggtgccc
    16921 ggcggcgcgg agcatctgca cgacggccgc gttgccgacg gcgccttgca agcccatgag
    16981 cgcgggcggt acgccccctc cggcacctcg gctcccctgt ctgcccggcg tacggctcga
    17041 cgtacgggta tgggccgaga cgggcgcggt accggggcta gggccctcgg acttctctcg
    17101 ggcgcgcatg gaccttctcc tcacatagga cgcaacccct cccgcacagc cgccgcgtct
    17161 ccgtggacgc aaggtccgtg cgggagggcc ttttcggctg cctgaccgcg cgctcgccgg
    17221 gctggctcag ccaacgttcg ccctgttgtc ggccggcggt gccggcttgc gctcagtggc
    17281 gcggttactc ggcgtcgagc tggtggtcgg cccagacgta gctttccggc agcaagtcgg
    17341 tgatagggac ggttcggacg cggtcgccct cgccgacgat gaccttgagg gcgggaaagt
    17401 agtcgagaag gacctgacgg caccggccgc acgggggaac aaccccccgg tcgcggtcgc
    17461 ccacggcgac gatcgtgtcc agctcgtagg cgccctgggc ggctgccgct ccgatgagga
    17521 ccagctcggc gcaggggcct ccggtgaagt ggtaggcgtt caccgccgtg acgatccggc
    17581 catcccgggc acgggccgcg gccgccatgg tgtggttgtc gcctcggcag cgagtgcgag
    17641 cgacgtgggc cgccgcctgg acgagttcgt ggtcgacgtg gtgggtctgc gtggtcatct
    17701 tctctgcctt tcgtcaggtg tcaggcgacg ttgacccagg tgacgagagt gcgcaaacga
    17761 atatcggcgg tgtgcttgtt ccgccagggc tccaggtcgg cttcgatgcc acgatggtca
    17821 agctgcgctg cccggagtaa gcccctcgat gaacggttga aagtccccag ccagtgcgag
    17881 ctccgtgctg aggtctgtat cgacttgccg cgccgacgaa gttctcgctg gaacaggcca
    17941 tcgtgctgcc tgattcggag gaggttgcac cgaccagggc cgttgcccgg gaggtagtag
    18001 acgtccatgg cggcggcgcg gacgagttcg cccgcgccgc cggctttcag ggcatgaccg
    18061 gtcatgcgtc gattctgccg aggcccactg acagcaccac ccccggcacg gccctgctca
    18121 ctgtgtgcgg taggcgtcga cgatggtctg ggtgagggtg ttcccgtcgg tgtcggtcag
    18181 ctctgcgcgc agcgtgactc cggtgcccgc gcgcgggttg cggatcgtga cggcgccgct
    18241 ctcgaccggg atccgggtcc aggaggcgcc accgtcgacg gacatcgaga tggtcagcga
    18301 gcggacgcgg ccgttcgccg ctgcgccctg cacggtgacg ggcacgcgga gtgccgtgtt
    18361 cgccgccgcg gttccggtcg ggctgagctc gggcgagaag cgcacggcgc tcaccggcac
    18421 cgggaccggg ccggtcgtcg tgcgcgaggc gaaggtccac gccgaggtca cctgggtggc
    18481 ggtgccgggt gcaccattgc gcttcaccgt gctggtgagg cggtaggacg cgtcgcccgc
    18541 cggcacggtg aacccggccc gtccgggggc tccggacttc gttccgacga gcacgccgtc
    18601 gcggtgcaga gtggtcgagg ccgaggcgta ggacggtgac gacggtacgt ggccgtcgcc
    18661 gtcggccagc atcgggacat cgacggtgag acggtcgccg tcgcggacga cgccggggcg
    18721 atcggggagg gccggtccga agacggcgtt gtcgaaggtg tgcgtggtcg tgctcccggc
    18781 gcgcacggcg atgccgttgg cggtgtatcg gttggaggcc ccgccgggcg cagcgggggg
    18841 ccagtaagtg acgtcccagg tgccgcgttc aggcgtgacg aagtaggtgg cgtcgccggg
    18901 gctcgcgagg cgctgggaga cgccgagggt cactccgcta ctcggctgca ggtcgatgga
    18961 cgcgggcccg gctccggtgg tgcccggccg ggccgcgcca cggatctgca gggcggccag
    19021 gtccttcgcg gaggggtgcc gggtgagtcc ggtcagggcg cgggggccgg tgaagacgta
    19081 gccgagcgcg tagtcggcgg acttggtcgt ccagtaggcg tcgaaccact gcttcaccga
    19141 gccgggttcg gcgtcggggc ccaggtgcgc gacgcgcagg ttcggcttgg cggccatccg
    19201 gttgaggagg cgagtggtgc cgccgtgctt gacctcgacg accatcatgc tgtgcaggaa
    19261 ctccgcggag ccgtcgggcg gccgtacgtc cacgggtgcg gtggtccgcg cgtcgaccgt
    19321 gacggtggtg tcgcgatcga ggtcgagtcg cggctggacg atccagtccg tgccgtccgt
    19381 gccgcccgcg gcgttgccgg tggtcaggta gctgtccagc acgtaacggc ccttgggcag
    19441 gcgcacggtg gtcgtgccgg aggcgtcgtg cggctggacg gatttgtcag cgccggggcc
    19501 ggagatgccg gtgacggtgg tggcgtagtc ccctgtcgag cggccgccgc ggtctaggtg
    19561 cttgatcgtg agactgtacg tctccggttc tgcggcgaag gccgtggcgt cccaagcggg
    19621 cgtcgcgctg ccgaccaggg cgacggcgac agccagggtc cggaggacgc tgcggcgggg
    19681 tacggaagaa gtggtcatga tctgcactgc tccgcggggc gccggagttc ctgtggcctg
    19741 cgtcactgaa agggtgctgt tgctgccgcc cggacggctc ctgtggtgca cgtcaccgga
    19801 accggtgcga ccgacgtggc agagcagaat gtggaatcac tcatgaggaa ccgcttccgc
    19861 cgcggagacc gcgacgcctt ggcggagctg tacgacgagc acgcccaagt gctgtaccgc
    19921 tacgccctgc gggtgacggg cgactgggcg gaggccgagg acgtcgtctc ggcatccttc
    19981 ctggaggcat ggcgcggccg ggagcgcgtg cggcccgacg gggacagcct gcgcccgtgg
    20041 ctgctgggaa tcgccaccaa catcatgcgc cgcaacgcac gcgcacgccg gctccgcgac
    20101 atcgcgctcg cccgtgtccc ggaacgcggc tcgattcccg acttcgccga cgacctcgtc
    20161 acgcacatgg cggacaccga gcaactgcgc gccgcacacg ccgcgctcgc ccgcctgcgg
    20221 cgccgcgacc gggaggtctt cactctggtg gtgtgggcgg gcctggacta cgcggcggcg
    20281 gccgaggcac tcggcgtgcc ggtcggtacg gtccggtcac gcctgtcccg tgcccgcact
    20341 cggctgcgcg aactcgccga cgccgaagcc cgcaccgcgc gctcgcaggc ttcgcggttc
    20401 tcgcggtctt cgcgggacgt ggccgagcgg cctcgtgcgg cggacagcgg gggcttctcc
    20461 ggaggagtcc tcgaagaagc ccctggagaa gtctccgcca cccccgacat gcccgtagcg
    20521 ggccgcatcc ccctggcccg gcccttgacc caggagaacc acggatgaac accaccccgc
    20581 ggcgacgtcc gctccacggg tccgaggaga ccgaacgcct cggcctcacc gacctgctgc
    20641 ccccaccacc ggtccccggc ctgaaccccg accgtgaact gctgctgaag gaagcactgc
    20701 tgcgcaaggc cgccaccgac gcaccgcgtg ggagcctcgc cgcccgggcc tcgcgcctgc
    20761 gcccgccccg gcgcctggcc gtccgggtca tggccccggc ggtcgcctgc gccctggccg
    20821 tcggcggcat cgtggcggtg aatctcgcgg acacgtccgg gcgcggcgcc cccgcggtcc
    20881 ctgggcgcga cggtgccgac cgtacccccg aagcgacgcg gctcctcgac cgcatcgccc
    20941 tcgccgccgc agcggcacca cagccgacgg tccgtgccga ccagttcgtg tacgtcgaga
    21001 gcaaggtcgc ctacgccgcg cagagcgccg cggggggctc cgtggccatg gctcctgtgc
    21061 gcacgcgtca ggtgtggctg tccgccgacg gcagccgccc cggcctgctg cgcgaggaag
    21121 gccgcgcaga cgcgccgctc ggcggcgacg acgctccggt ctacgccctc gacggcccgg
    21181 gggcgacgcc ccggccgacc acgctgcgca agggcccgtc gatcagtgac ccgacccacc
    21241 agtacgttgc ttcactgccc accgaccccg acgccctgct gaagctgatc tacgacgaga
    21301 cccgcggggg aggccgagcc ccggccccgg cctcg
//
