LOCUS       NZ_BMUT01000014        31631 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces hiroshimensis strain JCM 4586 sequence14, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUT01000014
VERSION     NZ_BMUT01000014.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces hiroshimensis
  ORGANISM  Streptomyces hiroshimensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 171175)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 90X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650335.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:32:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,830
            CDSs (total)                      :: 6,745
            Genes (coding)                    :: 6,620
            CDSs (with protein)               :: 6,620
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 25 of 125
            Pseudo Genes (incomplete)         :: 107 of 125
            Pseudo Genes (internal stop)      :: 4 of 125
            Pseudo Genes (multiple problems)  :: 11 of 125
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 80602
            Orig. end                         :: 112233
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUT01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31631
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="hydrogen-cyanide"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..31631
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21083
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21083
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11083](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11083)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    199..212
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(308..850)
                     /locus_tag="IE241_RS27700"
                     /old_locus_tag="GCM10010324_56560"
     CDS             complement(308..850)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627722.1"
                     /locus_tag="IE241_RS27700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56560"
                     /product="hypothetical protein"
                     /protein_id="WP_190024586.1"
                     /transl_table=11
                     /translation="MSQVRRGIMQALAWTLATAAAMAVSWYGVRTVLAGTAYEPPRALP
                     ISGTAAPGIGEPASSTRAPGPPPSPSPAGSAAPSGKPQAPTSTPAPGSGPAQNPEAQPR
                     PGDGEVKSYPVRGGRAVFDLGRSSATLVSATPEEGWQMRVWKQSAWIRVDFMAGTKTTS
                     VFVTWNGHPPQVQTVES"
     gene            884..1624
                     /locus_tag="IE241_RS27705"
                     /old_locus_tag="GCM10010324_56570"
     CDS             884..1624
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131808.1"
                     /locus_tag="IE241_RS27705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56570"
                     /product="response regulator transcription factor"
                     /protein_id="WP_190024587.1"
                     /transl_table=11
                     /translation="MARLLVVEDDPFVRSALIRQLTEASHTVRSVGTALEALREVAQVG
                     FDLVILDLGLPDLDGAQALKMLRGITDVPVIVATARDDEAEIIRLLTDGADDYLVKPFS
                     VAHLTARMAAVLRRAGRGGPAGEPAPSAALQVGGLSVDPLRRQAELDGAPLDLTRREFD
                     LLAYLAGRPGVVVPRKELLAEVWQQSYGDDQTIDVHLSWLRRKLGETAASPRYLHTVRG
                     VGVKLEPPETPPGPGTGTASPEKP"
     gene            1621..3021
                     /locus_tag="IE241_RS27710"
                     /old_locus_tag="GCM10010324_56580"
     CDS             1621..3021
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949798.1"
                     /locus_tag="IE241_RS27710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56580"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_190024588.1"
                     /transl_table=11
                     /translation="MRWALVRVSLAVTVMVVLAFAVPLGLVVKELARDRAFADAERQAA
                     QIRPALAITTDRDQLERAVASSQAGGDGRMAVHIPGGDGVPQGEGADAREGHQAYDIGP
                     RRADPHAVETARRGRSAVTSVPGGYALLQPTALSTGEFAVVEVYVPHRAVGNGVTTSWV
                     ILAGVGLGLIAGSLVTADRLGLRLVRPAERLAKAAVELGEGKLGVRVREDGPAELRAAA
                     VAFNSMADKIVQLLSHERELAADLSHRLRTPLTVLRLNAASLGEGPAAEQTRAAVAQLE
                     REVDQLIRAAREQGEQKERPTLGCDACEVIRDRMDFWSALAEDEGRTVRLSGVDETVRV
                     PVARPELAAALDAMLGNVFRHTPEGTDFAVDVHHSDDAVIVLVSDAGPGITDPDAALRR
                     GHGDGGPGSTGLGLDIVRRVAESTGGDVRIGRSVLGGTEVRVWLSPDGGGSRHRERRRR
                     VRRGRPRR"
     gene            3245..4696
                     /locus_tag="IE241_RS27715"
                     /old_locus_tag="GCM10010324_56600"
     CDS             3245..4696
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105712.1"
                     /locus_tag="IE241_RS27715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56600"
                     /product="cellulose binding domain-containing protein"
                     /protein_id="WP_190024589.1"
                     /transl_table=11
                     /translation="MGSSAHRRRVSRKAKLAGAGLAAAIATGAAFTLTGTAQAASVGAA
                     FSRTGAWSGGYTGQYVLTNDTGKDLPGWKLTFDLPAGTKITSLWNGKHTVSGRSVTVEP
                     EGWNATIAPGKSVTVGFVAARTGAGTDDAPANCRINGAKCSVDKSPGPQPTGSTGPTTP
                     TPAPTQSQPQPQPTVTSPAPGGASAAFAPYVDTSLYPAYDLLDTAKKTGVRNFNLAFVT
                     SGGGCTPKWGGVTDLGGDAVARQIGKLREAGGDVRVSFGGAAGSELGLVCSSADELAAA
                     YGKVVDAYKLTKVDFDIEGAALPDTAANTRRAQAIATLQKKHPGLDVSFTLPVMPTGLT
                     QDGVNLVENAKKNGVSVSAVNIMAMDYGSSFNGDMGQYAIDAATATHAQVKGVLGLSDK
                     AAWKAVAVTPMIGVNDVSAEVFKADDAAQLAAFGRSKGIGWLSMWSAARDKQCPGGAQN
                     SASATCSSVLQDELAFTKAFAARKG"
     misc_feature    4827..4843
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            4827..5873
                     /locus_tag="IE241_RS27720"
                     /old_locus_tag="GCM10010324_56610"
     CDS             4827..5873
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468016.1"
                     /locus_tag="IE241_RS27720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56610"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_190024590.1"
                     /transl_table=11
                     /translation="MRTRHKAVRMTLLGAAPLALTVLTAAPAGAHGSMTDPVSRVSACF
                     AEGPEHPRSAACKAMVAAGGTQPLYDWNEVNIGDAAGRHRRIIPDGKLCSAGRAKYKGL
                     DLPRADWPGTKLAPGKHTFRYRATAPHRGTFELYLTKDGYDPGKPLKWSDLEAKPFAKV
                     TDPTLKDGSYVFDGTVPKKSGRHLVYSIWQRSDSPEAFYTCSDVDFGGKGAGTKALAAP
                     ELDAPAPDAPAPAASAPSDRQIAEGAGKSTVDHGGHGGDGGDGGDGHGEHGRAGAGGAG
                     AGDPGAGNEPGSAVKAANAPAAQGGRLAETGGGDRTAVLAVTGAGVLAAGSATLFLALR
                     RRSARNHA"
     gene            complement(5939..6508)
                     /locus_tag="IE241_RS27725"
                     /old_locus_tag="GCM10010324_56620"
     CDS             complement(5939..6508)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004944067.1"
                     /locus_tag="IE241_RS27725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56620"
                     /product="universal stress protein"
                     /protein_id="WP_190024591.1"
                     /transl_table=11
                     /translation="MSGTVERVVVGVDGSAGSVAALRQGAQEAARHGAALCPVLAWSPP
                     GGEAADALQPAPADVRAHWEAQARRALAKTCERALGAAPFRLRVAPRVIRAQPGPALVA
                     SARHDTDMLVLGAGSHGLWHRFLHGSVSRHCLRHARGPVMVVHPGEADVKDARGAERPP
                     RRHAPVVVPVGPPDVWLRRTGPGRDG"
     gene            6800..7309
                     /locus_tag="IE241_RS27730"
                     /old_locus_tag="GCM10010324_56630"
     CDS             6800..7309
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS27730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_56630"
                     /product="hypothetical protein"
                     /protein_id="WP_190024592.1"
                     /transl_table=11
                     /translation="MARDDEQHTGRLWTVRITSDRYPQPGPMALRCSEPGCRPDPVPLP
                     SATAARTAAAGHLASHGHTAGPVPQATACRCGTDGCSWHARSVPGCEGRAVRQVITYTC
                     AGRVWRLAEMCAQCAGAIPDARILRPLNSHAGNPPGIQPDPTAIPPATVPPPGVQYAGP
                     VVVQTW"
     gene            complement(7297..8310)
                     /locus_tag="IE241_RS27735"
                     /old_locus_tag="GCM10010324_56640"
     CDS             complement(7297..8310)
                     /NRPS_PKS="Domain: NAD_binding_4 (17-191). E-value:
                     4.5e-19. Score: 60.5. Matches aSDomain:
                     nrpspksdomains_IE241_RS27735_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018509864.1"
                     /locus_tag="IE241_RS27735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56640"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_190024593.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7.3e-20, bitscore:
                     64.4, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.2e-23,
                     bitscore: 75.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.1e-18, bitscore:
                     60.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITDLNTTGDWAGRSVLVTGAEGFIGSTLVDLLVERGARVRVLVH
                     YKPYAERGHLARYLGPGSPVETLAGDVRDPGRVMDAVAGCDTVFHLAALIGIPYSYASP
                     EAYVQTNVAGTENVAAACRRHGVRRMVHTSTSEVYGTALTAPIGEDHPLQPQSPYSASK
                     IGADMLALSYAHSFELPVTVVRPFNTYGPRQSARAVIPTILAQLHSGAEEIRLGSTTPT
                     RDFTYVTDTAEGFLALADCDRAVGHAVNLGTGREISIGDLAESLVRASGRDAKVVVDPS
                     RLRPAGSEVERLLSDNSRAREWAGWRPRVELEEGLARTSDWVRDHLHLFAPDRYQV"
     aSDomain        complement(7738..8259)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE241_RS27735_NAD_binding_4.1"
                     /evalue="4.50E-19"
                     /label="IE241_RS27735_NAD_binding_4.1"
                     /locus_tag="IE241_RS27735"
                     /protein_end="191"
                     /protein_start="17"
                     /score="60.5"
                     /tool="antismash"
                     /translation="VTGAEGFIGSTLVDLLVERGARVRVLVHYKPYAERGHLARYLGPG
                     SPVETLAGDVRDPGRVMDAVAGCDTVFHLAALIGIPYSYASPEAYVQTNVAGTENVAAA
                     CRRHGVRRMVHTSTSEVYGTALTAPIGEDHPLQPQSPYSASKIGADMLALSYAHSFELP
                     VTVVRPFNTYG"
     CDS_motif       complement(8194..8268)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE241_RS27735_0001"
                     /evalue="1.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE241_RS27735"
                     /protein_end="39"
                     /protein_start="14"
                     /score="14.6"
                     /tool="antismash"
                     /translation="SVLVTGAEGFIGSTLVDLLVERGAR"
     gene            complement(8307..9503)
                     /locus_tag="IE241_RS27740"
                     /old_locus_tag="GCM10010324_56650"
     CDS             complement(8307..9503)
                     /GO_function="GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_transf_28"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611424.1"
                     /locus_tag="IE241_RS27740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56650"
                     /product="glycosyltransferase"
                     /protein_id="WP_190024594.1"
                     /sec_met_domain="Glyco_transf_28 (E-value: 1.3e-26,
                     bitscore: 86.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 2.1e-31,
                     bitscore: 102.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATADDTLSVVIGAGGTGGHIYPGLAVADALRRAVPHAVISFIGT
                     ERGLETRLIPDAGYRLHTVDMIPFDSSLGARRYLLPADLVRSGRQAQRVIEGQGAQVVV
                     GMGGYPSAPAVLGARMARRPVLVHESNAVPGRANRFAATLTPHVALAFDRTREHLPART
                     SVRAETVGMPLVSDVAGLDRAGRAALRGQARRWFGVPDDAWVVLFNGGSLGAARLTEAA
                     LQLALRWRGRPDVHLVIKTGPDALERVRARLAAEGGDRVATAVGYLDRMDLAYAAADVM
                     VCRAGSATVAELSSVGMPAVLVPYPHAPHDHQTHNARVLSDAGAGLLLPDGEATGERLA
                     ALIDPLLCDPGRLAAMGAAAHPGTHALAADLMAAWVLRLAGRAPVNPFPFQAVERNHA"
     misc_feature    complement(9526..9543)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.84"
                     /tool="antismash"
     gene            9613..9966
                     /locus_tag="IE241_RS27745"
                     /old_locus_tag="GCM10010324_56660"
     CDS             9613..9966
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241904.1"
                     /locus_tag="IE241_RS27745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56660"
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="WP_190024595.1"
                     /transl_table=11
                     /translation="MNENLPPCPECSSAYTYEMGVLLICPECGHEWSPAAAESADGDQE
                     NVIRDSVGNVLADGDTVTVVKSLKVKGSATGIKAGTKVRNIRLVDGVDGHDIDCKIDGF
                     GAMQLKSGVVRKA"
     gene            complement(10001..11083)
                     /locus_tag="IE241_RS27750"
                     /old_locus_tag="GCM10010324_56670"
     CDS             complement(10001..11083)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576972.1"
                     /locus_tag="IE241_RS27750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56670"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_190024596.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.4e-38, bitscore:
                     123.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTIAAAAQRRVAGCRHRFDTRFEAYFDALAENLDTPALSRFTP
                     RCLELLRDLSLRGGKRLRVALLYEAARLVTDERPPGLEEAALSIELLQTHGLVHDDIID
                     DAPVRRGGPSTYYAYRREFPGDDGTALGLAVLAGDLASFLSMHVLLEADAPAEIKQAML
                     GVQLRAGAETVAGQITDLERDFEPLPSEDLLHTVCEYKTTRYSILAPLRLGLLAAGENL
                     AEHDERLRRYATPAGISGQMRDDYLDLFGDESVTGKSPGSDIRSGRRSYALRAVLAAAT
                     AAERSLVESALGDPRCTAGTVDRIRKIALEHGVDDALRAGMRRYAEEAAAEASGWRPHW
                     REEAVAFFEGLPLWNVQRMQ"
     misc_feature    complement(11085..11101)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.35"
                     /tool="antismash"
     misc_feature    11209..11222
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.15"
                     /tool="antismash"
     misc_feature    11210..11226
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.19"
                     /tool="antismash"
     gene            11228..12538
                     /locus_tag="IE241_RS27755"
                     /old_locus_tag="GCM10010324_56680"
     CDS             11228..12538
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884183.1"
                     /locus_tag="IE241_RS27755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56680"
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="WP_229899897.1"
                     /transl_table=11
                     /translation="MRISAVAVCTAAAIAGGLQISPSAFGTDEKEPEAARPAVAPASTG
                     ADASAPENESASEDSGTSDTDGTPFKDGVMSLNTAVPHAPRAAAAAAAPPQGEGWKLSG
                     ATRMLPTGYTIKFYDQKSVDWLARYVQASAADLQRVTSLPVTVDTRPVGWDYSRPKGEV
                     VIGLLKRPCIPPADNGSKGWKIVRDGSGVKNLSCGFTASSVPGTVTSGHAYIDTEFFTA
                     DGKPLPAWGEPYMRNHISHELGHTLGLTHANRSAARGDCVKGTDSGEKPVMCTPTYAYQ
                     DKRAGTYVQQFDVQGLRFLAAGAGAALSPQGRVTGLGGKCLDVKGGSAANGTQIQLSTC
                     NGAVAQSWILGKDGTFRALGKCLDNARNAGTDGNKIDLYDCNGQPSQRWSVDAKGRIVH
                     VASGKVLDVTGGKTADGTKVQLFTANTNKRQVWVTPK"
     gene            complement(12615..13232)
                     /locus_tag="IE241_RS27760"
                     /old_locus_tag="GCM10010324_56690"
     CDS             complement(12615..13232)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS27760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_56690"
                     /product="hypothetical protein"
                     /protein_id="WP_229899899.1"
                     /transl_table=11
                     /translation="MSALPSETPLSVVRPPEPTRTLTSGARHARPLGLYDSWWTVAGAA
                     LMLCAVWAGCVWISFHLTADATLHTAALFVHLTGLVLGFGAVLVADYYGLLWITGRCSL
                     QEALGSAGRLHLPIWAGLVGLVLSGMLLHPSPSSTLTAVKLVLVLLLSLNGLQAGLLNK
                     RMAEQPSAAPAPRLLAWGGATALVSQICWWGAVVIGFLNSQH"
     gene            complement(13631..15997)
                     /locus_tag="IE241_RS27765"
                     /old_locus_tag="GCM10010324_56700"
     CDS             complement(13631..15997)
                     /EC_number="3.4.24.3"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057183.1"
                     /locus_tag="IE241_RS27765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56700"
                     /product="collagenase"
                     /protein_id="WP_229899901.1"
                     /transl_table=11
                     /translation="MSHSRSLRRSLRASLLTTAIATALCATAVQPVHADSPSPAPRPSA
                     AAPAAGVRQDTPTPNPFDEVTRLANAPKPASASPTAPGGLTDGRVPGALTAKPKPTAAA
                     PRATLGGTAVPCTLDGITRLAPEQLADFLADQAVTADGCLRTTLWTWDQRLAPVMSRAH
                     VQAVSRRIEGLAAAHDGKNGSHLLEMFTYLHAVAYHDFSRTEIDVTDAPTVEAMRRAVS
                     AFGTAAHTFDVTRTNAETLREALYAASAPGLRQHQLPLIKRVLATMDAEHPGTAKDTSW
                     AGAALAALSLNYLGVYPGNHDAAFHAAVAADTSYRAAFKAFAGYTHLKGTSNAWVVRDA
                     VGEYGRMGQIDALRSEITSALGGLLATTTGNFGEGSEPWAKVVTWLIAFDACKQYGVCK
                     ADIERRIFPSTYTYDNGGIKVRTALPRATVDRLYYASKQVKAQFHRVLGTEQPLAGDTN
                     TTLNIVLYASRADYEVYHPLLTGMGTNNGGIYIENGATFYTYERRVPQDSTLTLEELFR
                     HEYTHYLNGRWAVPGLFGEGPWYQGDRTTAMDEGTAEFFDGATRGEGIRVRKSLVQSII
                     NDTAGGTKPRMSVYELLHAEYDRDGFRFYSYAGTFFEFLWSEHPSLLREMYGHLRDNDV
                     AGFDAWRDRLGRDGGLQRAYDTFLDQQIAKVKNLYVPSTSFRPVGGLDAGHPATVRASF
                     KATTGITPECRTNEAPERPRFTCTGRITANLNSPGSPDLVFKDMSGTVDYFILDRTKKG
                     TNNFADMNCSFGKVDLWSDRPAGSADFTCEGPLRG"
     misc_feature    complement(16167..16183)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.4"
                     /tool="antismash"
     gene            complement(16198..17217)
                     /locus_tag="IE241_RS27770"
                     /old_locus_tag="GCM10010324_56710"
     CDS             complement(16198..17217)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267161.1"
                     /locus_tag="IE241_RS27770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56710"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190024598.1"
                     /transl_table=11
                     /translation="MTAGTAPLPSVPPPSVPLLSVRDVTMTFPGRRGGRSAPVRAVDGV
                     SFDLAAGKTLGLVGESGCGKSTTGRMIVRLLEPTTGSITYDGRDISRLGRRELKPLRKD
                     LQMVFQDPHSSLNPRQTVARIIADPLLVQGMAAAGARKRAAELMEMTGLIPEHIDRYPH
                     EFSGGQAQRIGIARALATGPRLIVADEPVSALDVSVQAQIVNLMERLQRELGLAYLFIA
                     HDLSVVKRVCNRVAVMYLGRIVEVGDKERVYAAPAHPYTQALLSAVPLPDPVAERARER
                     ITLLGDPPSPAAPPSGCTFHPRCPKAQEICRTEAPLLRVAAPGEAREVACHFAAADNP"
     gene            complement(17214..18284)
                     /locus_tag="IE241_RS27775"
                     /old_locus_tag="GCM10010324_56720"
     CDS             complement(17214..18284)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010037604.1"
                     /locus_tag="IE241_RS27775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56720"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_190024599.1"
                     /transl_table=11
                     /translation="MAAQAVPTDPAAPAGPAASEEQPLLSVTDLTVTFPTRHGDVRAVD
                     SLSFAVRRGQTLGIVGESGSGKSVTSLAVMGLHTGARVTGSIALVGRELNGLPERELNR
                     LRGRRMAMIFQDPLSSLHPYYTVGEQIAEHHRVHFGSRRAAARKRAVEMLAEVGIPEPA
                     RRAGEYPHQFSGGMRQRVMIAMALACEPDLLIADEPTTALDVTVQAQILELIARLQEQR
                     GLAVVMITHDLGVVARVAREVLVMYGGRAAEQAPVDTLFADPGHPYTRGLLDSLPRLDD
                     SDDAPLRAIPGSPPSLLDPAPGCAFSPRCPRAAAATPAERAHCAGVRPELRPSQGHLVS
                     CHLSLHTAARVQGGTR"
     gene            complement(18284..19270)
                     /locus_tag="IE241_RS27780"
                     /old_locus_tag="GCM10010324_56730"
     CDS             complement(18284..19270)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237880.1"
                     /locus_tag="IE241_RS27780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56730"
                     /product="ABC transporter permease"
                     /protein_id="WP_190024600.1"
                     /transl_table=11
                     /translation="MTLYLGRRLLAVAGVLVAIAAVTFTVFYVLPSDPAAAACGKSCST
                     DRLEAIRAHMGLDRPLWRQFADFVTGIFTGRTMGSGQYALHCAFPCLGYSYENSEAVWD
                     LLMDRLPVSASLALGAAVLWLALGLSAGVTAALRKDSLTDRALMVGAVAAASLPVYFTS
                     MMLIYGLIRTAGLLPYPQYVPLGDDPLHWASNLLLPWLALAVLYAAMYARQSRSSMIET
                     MAEPYIRTARAKGLPRRTVVVKHGLRAGMTPILTLFGMDLGGLLAGAVITESIFGLPGI
                     GRLFYGALSTGDQPVILGVTLLAAAFIVVANLAVDLLYAVVDPRVRY"
     cand_cluster    18563..31631
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    18563..31631
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[23562:26631](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      23563..26631
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="2"
     gene            complement(19267..20217)
                     /locus_tag="IE241_RS27785"
                     /old_locus_tag="GCM10010324_56740"
     CDS             complement(19267..20217)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543031.1"
                     /locus_tag="IE241_RS27785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56740"
                     /product="ABC transporter permease"
                     /protein_id="WP_190024601.1"
                     /transl_table=11
                     /translation="MTTTPTPASSPAPAAVPAGSGPWQLARAELRRRTAVKVSLAVVAL
                     FLLMAAGAPLLSSLAGWSPEEFDKTAVDPYLGGRPLGPLGGISADHWLGVEPVTGRDLF
                     ARVVHGAQVSLLIALTATAIVVLAGTAAGITAGYFGGRTDAVLSRLMDLTMSFPSLIFM
                     IAMMSVAKDVNRILLMTAVIGLFGWPGVARVVRGQTLSLRHREYVDAARVGGSGPWRIL
                     TRDILPGVAGPVIAYTTLIVPGMIATEAALSYLGVGVRPPTPSWGQMIAESVAFYDTDP
                     MYFVIPSTCLFLTVLAFTLLGDALRDVLDPRSGRT"
     gene            complement(20231..21976)
                     /locus_tag="IE241_RS27790"
                     /old_locus_tag="GCM10010324_56750"
     CDS             complement(20231..21976)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378669.1"
                     /locus_tag="IE241_RS27790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56750"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_190024602.1"
                     /transl_table=11
                     /translation="MNKRTCTALAAVLAASFALGTAGCSGGKQSAGGKDGKNPAAAHEG
                     TAIGGTPQKGGTLTVLSNQDFTHLDPARNWVMNDMDFGTRLLYRTLVTYKATPGTQGGG
                     LVPDLATDLGTPSADARTWTFHLKQGVKYEDGSPVTAQDVKYNVERSFSPDLPGGADYA
                     ARYLAGAEGYRGPAQGRHLDSVKTPDDRTIVFELRKPFAEFPNATVMPTFAPVPQAQDK
                     GPQYDNRPFSSGPYKVDSYARGKKLVLVRNDHWDPGTDEVRKAYPDKLVVLMGLKANQI
                     DDRLIASQGADASAVSWGALRPESAAKVLPDARVRERLLAESTNCTDMVQMHTGRAPFD
                     DPKVRRAVQYALDRDAVLTASGGPAFNDLSTAYMPASLFGGKQPDTLKIPVTGDADKAR
                     QLLKEAGKPDGISTKITASAGDKGRAEAVQQSLGRAGIKVTIETVDPSAFYATIGDTEN
                     RTDMVYTGWCPDYPSGSTFLPFVFDGRFIKEKGNSGNHSLFRDDATMKRMDEIGAMTDT
                     KAAAEAWQQLDGRILAQAPTVPVLVRRWPLVLGTNIAGAYGHTSFGGQIDYATVGLKDP
                     AKSRD"
     misc_feature    22015..22025
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    complement(22041..22051)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            22104..23474
                     /locus_tag="IE241_RS27795"
                     /old_locus_tag="GCM10010324_56760"
     CDS             22104..23474
                     /EC_number="3.4.11.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452313.1"
                     /locus_tag="IE241_RS27795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56760"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_229899903.1"
                     /transl_table=11
                     /translation="MQEPAVAAIRTVSHDLPVSAEFEAFMAEGWAATPLPADIRLPVAD
                     LAAARRAKLSARFPGERLIVPAGEFKVRSNDCDYRFRPHSAYAWLTGLTGEEQAGHVLV
                     LEPDGPHRHEAVLYVRPRSPRAGEEFYRDRRYGEFWVGRRPDLAEAERLTGIRCVHRED
                     YDRLPPGRDASGDAELAAALSELRLVKDAWEVAQLQLAVDHTAAGFEDVVRALPRALAH
                     PRGERWIEGVFGLRARAEGNGPGYETIAASGAHACVLHWIRNDGRLDPRELLLLDAGVE
                     TDTLYTSDITRTLPLSGRFSPVQRQVYELVLAAQDAGMAALKPGASFRDFHRAGMRVIA
                     EGLAEWGVLKSAEGDFHRRYTLCSSGHMLGLDVHDCAQARADAYLDGVLEEGQVLTVEP
                     GLYLQPDDETLPAELRGIGVRIEDDLVITADGARLMSHALPRTPDAVEAWMGELLGG"
     misc_feature    23535..23545
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    23538..23553
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.3"
                     /tool="antismash"
     gene            23563..24708
                     /locus_tag="IE241_RS27800"
                     /old_locus_tag="GCM10010324_56770"
     CDS             23563..24708
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038321.1"
                     /locus_tag="IE241_RS27800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56770"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_190024603.1"
                     /sec_met_domain="DAO (E-value: 7.2e-67, bitscore: 219.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNSSSDVIVVGAGVVGAACAYYAARTGLSVTVVDRGPVAGGTTG
                     AGEGNLLVSDKEPGPELELALLSTRLWHELARELPAGIEYEAKGGLVVASDAHAMAALR
                     KFAAAQAEAGVTTEEIPADRLHEAEPHLAPGLGGGFRYPQDAQVQPALAAAHLLRASGA
                     RVRTGEEVAAVLTGANGEVRGVRTTAGELHAPFVVNAAGTWGGEVARLAGGRLPVLPRR
                     GFVLVTEPLPRVVRHKVYAADYVADVASGSAALQTSAVVEGTPAGPVLIGASRERVGFD
                     RTLSVEVLRRLAAQATALFPVLAGVRAMRTYAGFRPYLPDHLPAIGPDPRVPGLLHACG
                     HEGAGIGLAPATGLAVARQLTGGEPPLDLGPFHPGRFAAAA"
     gene            24780..25094
                     /locus_tag="IE241_RS27805"
                     /old_locus_tag="GCM10010324_56780"
     CDS             24780..25094
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237883.1"
                     /locus_tag="IE241_RS27805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56780"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_087924869.1"
                     /sec_met_domain="Fer2_4 (E-value: 2.2e-28, bitscore: 91.5,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTPADLVRAEPDPPFEITFDGRTVTALPGQSVAAALWAAGILA
                     WRTTRHGGRPRGAFCGIGQCYDCLATVNGEPNRRACLVPARPGDAITTQEGHGHAGLAV
                     "
     gene            25075..26631
                     /locus_tag="IE241_RS27810"
                     /old_locus_tag="GCM10010324_56790"
     CDS             25075..26631
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038323.1"
                     /locus_tag="IE241_RS27810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56790"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_190024604.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.5e-23, bitscore:
                     75.5, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 3e-13, bitscore: 43.3,
                     seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGSPSEPYDLVVIGAGPAGLAGAVTAARLGLSVAVVDAAAQTGG
                     QYFRHPAPGLGAARPQALHHDWPAFAELRGRFEASGAAHLAGHHVWAVTRQDEEMWSVH
                     ALVGEDSGAVGSGTGSAEVSGSPSGGGTGSDGEGRTHEGFSAERERPVRLQARAVLFAT
                     GAGERHLPFPGWTLPGVVGAGGAQAMLKSGLVLPGQRVVVAGSGPLLLAVASSLAAAGA
                     HVPEVAEASGYLGYARRPRALAANPHKLLEAAVHGTALLRHRIPLRTRSAVTAVHGTDR
                     VEAVTVSRLDRDWRALPGTGRRIACDALAVGHGLAPQTELATGLGCATRRTPDGTHALV
                     LDGLQETSVPGLWAAGETGGTGGWQLARTEGELAGIAVAARLRALPALTRSRRVRDLAR
                     RRDRMRAFAEAMVAAHAPGPGWTAWLDDDTDVCRCEEVTAGSIRDAVTALGARDARTVK
                     LLTRAGMGWCQGRMCGAAVACLAASGTAQGTVPPSADRRPLAVPVPLGALAALPEEPGH
                     A"
     gene            26695..27603
                     /locus_tag="IE241_RS27815"
                     /old_locus_tag="GCM10010324_56800"
     CDS             26695..27603
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543026.1"
                     /locus_tag="IE241_RS27815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56800"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_190024605.1"
                     /transl_table=11
                     /translation="MTASSWTPDRPWRGIMVATALPLRADLSVDYDAYAEHVRTLIESG
                     CDGVVPNGSLGEYQTLTPEERARVVRTAVEAAGDGARVMPGVAAYGSAEARRWAEQAAE
                     AGCGSVLLLPPNAYRADEEAVRAHYTEVAAAGIPVVAYNNPIDTKVDLTPALLARLHAE
                     GSIVAVKEFTGDVRRAYEIAELAPELDLLIGADDVLLELAAAGAVGWIAGYPNAFPTTC
                     AALYHAAVAGDLQTALPLYRSLHPLLRWDSKTEFVQAIKLSMDITGQHGGPTRPPRSPL
                     TGETEAAVRAATEKAVADGHH"
     gene            27688..28692
                     /locus_tag="IE241_RS27820"
                     /old_locus_tag="GCM10010324_56810"
     CDS             27688..28692
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="IE241_RS27820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56810"
                     /product="proline racemase family protein"
                     /protein_id="WP_190024606.1"
                     /transl_table=11
                     /translation="MRTRHVFHAVDSHTEGMPTRVITGGVGVIPGATMAERRLHFIEHM
                     DHLRTLLMYEPRGHASMSGAILQPPTRPDADYGVLYIEVSGVLPMCGHGTIGVATVLVE
                     TGMVPVSEPVTTVRLDTPSGLITVDVQVEDGAAKAVTLINVPSFSVGLDRKADVPGYGT
                     VTYDLAFGGNFYAFVELDSLGLPFDRARKDDLLAAGLAVMETVNASPDRPVHPEHPEIN
                     GLKHVYLAAPGSDARHSVHAMAIHPGWFDRSPCGTGTSARMAQLHARGALPLDRDFVNE
                     SFIGTRFTGRLVGETQVGGVPAVVPAITGRAWITGTAQYFLDPDDPFPGGFLL"
     gene            28689..30059
                     /locus_tag="IE241_RS27825"
                     /old_locus_tag="GCM10010324_56820"
     CDS             28689..30059
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139735.1"
                     /locus_tag="IE241_RS27825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56820"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_190024607.1"
                     /sec_met_domain="Aldedh (E-value: 4.2e-128, bitscore:
                     421.0, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAPTSFASHNPADPSDTVTEVPAPGASAAAEAVEQARAAQPGW
                     LQAGAAARSSALSAVAAAVEAASGELAALAVREVGKPLAEARAEVARTAAIWRYYAQAP
                     YEPTGAVHETAGGPGLLLTRRRPHGVAGLITPWNFPFAIPSWKAAPALAAGNTVVLKPA
                     PEATACALRLAELVRQAVPAEVFTVVPGGATEGGAVLATADAVSFTGSTAVGSAVTRAA
                     TARGIPVQAETGGLNAAIVLPDADIERAAAHIAAALAGYAGQKCTATSRVIAVGTALDP
                     LREALAAALRALPVGDPADAATVCGPLISARARDRFDQALSGASVLAAGAAPEGPGWYA
                     APTVVEKVPAGHRLLTEEVFGPVAALLPADDLAHAVRISNSVPYGLVTSVHTGGLEAAL
                     HGLDHLDTGMIRVNAPSTGVDFHLPFGGTKASGHGPREQGRAALDFYTSGRTYTLAP"
     misc_feature    complement(30065..30081)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.6"
                     /tool="antismash"
     misc_feature    complement(30067..30077)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            30191..30868
                     /locus_tag="IE241_RS27830"
                     /old_locus_tag="GCM10010324_56830"
     CDS             30191..30868
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891277.1"
                     /locus_tag="IE241_RS27830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_56830"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_190024608.1"
                     /transl_table=11
                     /translation="MGHLKQRTLITATERLRDQVAHALRAALISGELRPGEVYSAPQLA
                     EDFGISATPVREAMLDLAREGLVEPVRNKGFRVTEVNERDLDQYTEIRTLIEVPTTGRV
                     TRTAAREDLEALRPVAEEIVRAARDHDLIGYLEADRQFHLTLLALSGNERLVETVGDLR
                     KRSRLYGLTALDQRGELIPSAEEHLEILDLMLAGDAEGAEQCMARHLGHVRSLWARGSD
                     KDS"
ORIGIN
        1 gcaggccccg ggacctggga gaagagcgcg agcgggagcg agccgaacag ggcgtagagg
       61 gccgtgccgg gtgcgccgaa gccgtagcgc aagacgtaga agccggtgag cccggagacg
      121 gtggcccagg cggcacgccg gaggtgctcc ggcccctggt cctgctgcag cagccaccgg
      181 agtgggcggg tcacgtctgt caccctaggt gagctgcgcg ccttcgcaac cgggacggtc
      241 ggtcgccccc gcccccgccc ccgcccccgc ccccgccccc gtccccgtcc ccggcctcgt
      301 ccccgtctca gctctccacc gtctggacct gcggcgggtg gccgttccag gtgacgaaca
      361 ccgacgtcgt cttcgtaccg gccatgaagt ccacccggat ccaggcgctc tgcttccaca
      421 cccgcatctg ccacccctcc tccggcgtcg ccgagacgag cgtggcggag ctccggccga
      481 ggtcgaagac cgcccggccg ccccggaccg gatagctctt cacttcaccg tcgcccgggc
      541 ggggttgggc ctcggggttt tgcgccggcc cggatcccgg tgcgggcgtg gacgtgggcg
      601 cctgcggctt tccggacggg gctgcggagc ccgccggtga cggggagggc ggtgggcccg
      661 gggcgcgggt cgaggaggcc ggttcgccta ttcccggcgc cgccgtgccg gagatcggca
      721 gcgcgcgcgg cggctcgtag gccgtgccgg ccagcacggt gcgcaccccg taccaggaca
      781 ccgccatggc ggccgcggtc gccagcgtcc acgccagggc ctgcatgatt cctcgtctca
      841 cctggctcat ggtgcctcac ccgtatggcg tacggtgcgg gccatggcaa gactgctcgt
      901 agtcgaggac gacccgttcg tgcgctccgc cctcatccgg cagctgaccg aggcctcgca
      961 caccgtccgc agcgtcggaa ccgctctcga ggcgctgcgc gaagtggcac aggtcggctt
     1021 cgacctggtc atcctcgacc tgggactgcc ggacctcgac ggggcccagg ccctgaagat
     1081 gctgcgcggc atcaccgacg tgcccgtcat cgtggccacc gcacgcgacg acgaggcgga
     1141 gatcatccgg ctgctcaccg acggcgccga cgactacctg gtcaagccgt tctccgtggc
     1201 gcacttgacc gcgcgcatgg ccgccgtgct gcgccgggcc ggccggggcg gaccggcggg
     1261 agagcccgcg ccgtccgccg cgctgcaggt cggcggcctg tcggtcgacc ccttgcgccg
     1321 gcaggcggaa ctggacggtg ccccactgga cctgacgcgc cgtgaattcg acctgctggc
     1381 ctacctggcc ggccgcccgg gcgtcgtcgt cccgcgcaag gaactcctcg ccgaggtctg
     1441 gcagcagtcc tacggggacg accagaccat cgacgtgcac ctgtcctggt tgcgccgcaa
     1501 gctcggcgag accgccgcca gcccccgcta cctgcacacc gtccgcgggg tcggcgtgaa
     1561 gctggagccc ccggagacgc cgccgggccc ggggacgggg acggcgtctc cggagaagcc
     1621 gtgagatggg cgctcgtcag ggtctcgctg gccgtcacgg tcatggtggt gctggccttc
     1681 gccgtgccgc tcggcctggt ggtcaaggag ctggcccgcg accgcgcctt cgccgacgcc
     1741 gaacggcagg ccgcccagat ccggcccgcg ctcgccatca ccaccgaccg cgaccagctg
     1801 gaacgggcgg tcgccagctc ccaggcgggc ggagacgggc ggatggccgt ccacataccc
     1861 ggcggcgacg gcgtaccgca aggggaaggc gctgatgcgc gcgaggggca ccaggcctac
     1921 gacatcggcc cccgccgggc cgacccgcac gccgtggaga cggcccgccg cggccgctcc
     1981 gccgtcacgt ccgtgcccgg cggctacgcc ctgctgcagc cgacggccct gagcaccggc
     2041 gagttcgcgg tggtcgaggt ctacgtgccg caccgcgccg tcggcaacgg cgtcaccacc
     2101 tcctgggtga tcctcgccgg cgtgggcctc ggcctgatcg ccggctccct cgtcaccgcg
     2161 gaccgcctcg gactgcgcct cgtacgcccg gcggagcggc tcgcgaaggc cgccgtcgaa
     2221 ctgggggagg gcaagctggg cgtccgcgtg cgcgaggacg ggccggccga actgcgcgcc
     2281 gcggccgtcg cgttcaactc catggccgac aagatcgtgc agctcctctc ccacgaacgc
     2341 gaactcgccg ccgacctctc ccaccgcctg cgcacccccc tcaccgtcct gcgcctcaac
     2401 gccgcatcgc tcggcgaggg cccggccgcc gagcagaccc gcgccgccgt cgcccagctg
     2461 gagcgcgagg tcgaccagct gatccgggcg gcccgcgaac agggcgagca gaaggaacgg
     2521 cccacgctcg gctgcgacgc ctgcgaagtg atccgcgacc ggatggactt ctggtcggcg
     2581 ctggccgagg acgaggggcg cacggtccgg ctctcgggcg tcgacgagac cgtgcgcgtc
     2641 cccgtcgccc gccccgaact cgccgccgcg ctggacgcga tgctcggcaa cgtcttccgg
     2701 cacacccccg agggcaccga cttcgcagtg gacgtgcacc acagcgacga cgccgtcatc
     2761 gtgctcgtct ccgacgcggg cccgggcatc accgacccgg acgcggcact gcgccgcggc
     2821 cacggcgacg gcggccccgg ctccaccggc ctcggcctgg acatcgtgcg ccgcgtcgcg
     2881 gagtcgacgg gcggtgacgt acggatcggg cggtcggtgc tcggcggcac ggaggtgcgg
     2941 gtgtggctct cgccggacgg cggcggctcc cggcaccgcg agcgccgccg ccgggtacgg
     3001 cgcggccggc cgcgccgttg agcctggtcg ccgacccgcg cgccgccctc cgtttccggc
     3061 tccgccccgc cggctccgtc ggccgacctg cggcgccacc cccctcatta acccccgccg
     3121 atgccttcct taagcccgcc ataaggagtg ggcccgggaa ggcgattcgg cgatttgcct
     3181 ggtttgctct cgctagcgtg ccgcaggtac ccaccccccc caacccagaa caggcaggca
     3241 cgcgatgggt tcctccgcac accgccgacg agtgagccgc aaggcgaagc tcgccggcgc
     3301 cggcctcgcc gcggcgatcg cgacgggcgc cgcgttcacc ctcaccggca cggcgcaagc
     3361 cgcctcggtc ggcgcggcct tctcccggac cggcgcctgg tcgggcggct acaccgggca
     3421 gtacgtcctc accaacgaca ccggcaagga cctgccgggc tggaagctca ccttcgacct
     3481 cccggccggc acgaagatca cctcgctgtg gaacggcaag cacaccgtca gcgggcgcag
     3541 cgtcaccgtc gagccggagg gctggaacgc gaccatcgcc cccggcaagt ccgtgaccgt
     3601 cggtttcgtc gccgcccgca ccggcgccgg tacggacgac gcccccgcca actgccggat
     3661 caacggcgcg aagtgttccg tggacaagag ccccggcccg cagcccacgg ggtccaccgg
     3721 gcccaccacc cccacgcccg ccccgacaca gtcgcagccg caaccgcagc cgaccgtaac
     3781 ctcgcccgcc cccggaggcg cgagcgccgc gttcgccccg tacgtcgaca cctccctcta
     3841 tcccgcctac gacctcctcg acaccgccaa gaagaccggc gtcaggaact tcaacctcgc
     3901 cttcgtcacc tcaggaggcg gctgcacgcc caagtggggc ggcgtcaccg acctcggggg
     3961 cgacgccgtc gcccggcaga tcgggaagct gcgggaggcg ggcggcgacg tacgggtctc
     4021 cttcggcggc gccgccggct ccgagctggg actcgtctgc tcctccgccg acgaactcgc
     4081 cgccgcgtac ggcaaggtcg tggacgcgta caagctcacc aaggtggact tcgacatcga
     4141 gggcgcggcc ctgcccgaca ccgccgccaa cacccggcgc gcccaggcga tcgccacgct
     4201 ccagaagaag caccccggtc tcgacgtctc cttcaccctc ccggtgatgc ccacgggcct
     4261 cacccaggac ggcgtcaacc tggtcgagaa cgcgaagaag aacggcgtgt ccgtctccgc
     4321 ggtcaacatc atggcgatgg actacggttc gtccttcaac ggcgacatgg ggcagtacgc
     4381 gatcgacgcc gccactgcga cgcacgcgca ggtcaagggc gtgctggggc tgagcgacaa
     4441 ggccgcgtgg aaggccgtgg cggtcacccc gatgatcggt gtcaacgacg tgtccgccga
     4501 ggtcttcaag gccgacgacg cggcgcagct ggccgcgttc ggccggtcca aggggatcgg
     4561 ctggctgtcg atgtggtccg ccgcgcgcga caagcagtgc ccgggcggcg cgcagaactc
     4621 cgcgtccgcg acctgcagct cggtcctgca ggacgaactc gccttcacca aggcgttcgc
     4681 cgcccgcaag ggctgacaca caggccgcaa gggctgacgc acttcccgtt cccctggtac
     4741 cccccacacc gccccgcacg cacggcaccc cccacttcac ggccggcgtg cggggccacc
     4801 ccctcaccac ccacaaggag acccgcatgc gcacgcgtca caaggccgta cggatgaccc
     4861 tgctcggcgc cgcccctctc gcgctcaccg tgctgaccgc cgcaccggcc ggggcgcacg
     4921 gctccatgac ggacccggtc agccgggtgt ccgcctgttt cgcggagggg ccggaacatc
     4981 cgcgctcggc cgcctgcaag gcgatggtcg cagcgggcgg cacccagccg ctctacgact
     5041 ggaacgaggt caacatcggc gacgccgccg gacgtcaccg ccggatcatc ccggacggca
     5101 agctgtgcag cgccggccgc gccaagtaca aggggctgga tctgccgcgc gccgactggc
     5161 cgggcacgaa gctggccccg ggcaagcaca ccttccggta ccgggcgacc gcaccgcacc
     5221 gcggcacgtt cgagctgtac ctcacgaagg acggctacga ccccgggaag ccgctgaagt
     5281 ggtccgatct ggaggccaag ccgttcgcca aggtcaccga ccccacgctg aaggacggga
     5341 gctacgtctt cgacggcacc gtcccgaaga agtccggccg ccacctcgtg tacagcatct
     5401 ggcagcgctc ggacagccct gaggccttct acacctgctc ggacgtggac ttcggcggaa
     5461 agggcgcggg gacgaaggca ctggccgccc ctgaactgga cgcccccgca ccagatgccc
     5521 ccgcaccggc cgcgtccgct cccagcgacc ggcagatagc cgagggggcc gggaagtcga
     5581 cggtcgacca cgggggtcac ggcggtgacg gcggtgacgg cggtgacggc cacggcgagc
     5641 acggccgggc cggggccgga ggcgccggag cgggggaccc cggtgccggg aacgagcccg
     5701 ggtccgcggt gaaggcggcc aacgccccgg ccgcccaggg cgggcgcctt gccgagaccg
     5761 gcggcggcga ccgtacggcc gtgctggccg tcacgggcgc cggcgtcctg gcagccggtt
     5821 ccgccaccct cttcctggcc ctgcggcgac gctcggcccg caaccacgcc tgaaaccgga
     5881 cggcaggtcg gcaggtcggc cggtcggccg ggcgatcagg cgcccgggcg cccggcggtc
     5941 agccgtcgcg cccggggccc gtccgccgga gccatacgtc cggcgggccg accggcacca
     6001 cgaccggagc gtgcctccgc ggcggccgct ccgccccgcg ggcgtccttc acgtccgcct
     6061 cgccggggtg gacgaccatg acggggccgc gggcgtgccg gaggcagtgg cggctgaccg
     6121 agccgtggag gaagcggtgc cacagcccgt ggctgcccgc cccgagcacc agcatgtccg
     6181 tgtcgtgacg ggcgctggcc accagggccg gtccgggctg cgcgcggatg acccgcgggg
     6241 ccacccgcag gcggaaaggc gcggcgccga gcgccctctc gcacgtcttc gccagagccc
     6301 tgcgggcctg tgcctcccag tgcgcacgga cgtcggccgg cgcgggctgc aaggcgtccg
     6361 ccgcctcccc gcccggcggc gaccaggcca gcaccgggca cagggccgcg ccgtggcggg
     6421 ccgcctcctg cgcgccctgc ctcagcgcgg cgacactccc tgccgaaccg tccacgccga
     6481 ccacgacgcg ctccaccgtt ccggacatgc catccgcctt cctcgggatt ccgctgaatc
     6541 cgctgatccg ctgtacggca acgtggtcca cgctaggaag cgcccgccgg atacgtatcg
     6601 tccgaatggg tggcaaatcg ggcaataacc ccctccagtc ggagggggtc cgttcgacgg
     6661 accgggaaat cccgtccccg ggatcgggaa atcccctccc ggagggtgcc gccggcccgc
     6721 ccgggaaccg cagtcttgga cgagaccggt gacgagacga gtgacgaccg gtaacgaaca
     6781 cggaacccgg gaggcacgtg tggcgcggga cgacgagcag cacaccgggc ggctctggac
     6841 ggtgcggatc acctcggacc ggtatccgca gccggggccc atggcactcc ggtgctccga
     6901 gcccggatgc cggcccgacc ccgtcccgct gccgtccgcc acggccgccc gtacggccgc
     6961 ggcgggccac ctcgcctccc acgggcacac ggcgggcccg gtgccgcagg cgaccgcgtg
     7021 ccgctgcggc acggacggct gctcgtggca cgcccggtcc gtcccggggt gcgaggggcg
     7081 ggcggtccgg caggtgatca cctatacctg cgcgggccgg gtgtggcgcc tcgccgagat
     7141 gtgcgcgcag tgcgccgggg caataccgga cgcccggata ctgcgcccgc tcaacagcca
     7201 cgccggcaac ccgcccggca tccagcccga cccgaccgcg atcccgcccg ccactgtgcc
     7261 gccacccggc gtgcagtacg ccgggcccgt cgtcgttcag acctggtagc ggtccggggc
     7321 gaagaggtgc aggtggtccc ggacccagtc cgaggtgcgg gccaggccct cctccagttc
     7381 cacccggggc cgccacccgg cccactcccg ggcccggctg ttgtccgaca gcagccgttc
     7441 cacctcactg ccggcgggcc gcagccgcga cgggtccacc acgaccttcg cgtcccgtcc
     7501 ggaggcccgg accagcgact cggcgaggtc tccgatggag atctcccgcc cggtgccgag
     7561 gttgacggcg tgccccacgg cccggtcgca gtccgcgagc gccaggaagc cctcggcggt
     7621 gtcggtgacg taggtgaagt cgcgcgtcgg cgtcgtggat cccagccgga tctcctcggc
     7681 cccggagtgc agctgcgcga ggatcgtcgg gatcaccgcg cgcgccgact gccgcggccc
     7741 gtaggtgttg aagggccgca cgaccgtcac cggcagctcg aaggagtgcg cgtaggacag
     7801 ggccagcatg tccgcgccga tcttcgaggc cgagtacggc gactgcggct gcagcgggtg
     7861 gtcctcgccg atcggcgcgg tcagggccgt gccgtacacc tcgctggtcg aggtgtgcac
     7921 catgcgccgc accccgtggc ggcggcaggc cgcggccacg ttctccgtac cggccacgtt
     7981 ggtctgcacg tacgcctcgg gcgacgcgta gctgtacggg atgccgatca gtgccgccag
     8041 gtggaagacg gtgtcgcacc cggccaccgc gtccatcacg cgcccggggt cgcggacgtc
     8101 accggcgagc gtctccacgg gcgagccggg cccgaggtag cgggcgaggt gcccgcgctc
     8161 ggcgtacggc ttgtagtgca ccaggacccg cacccgcgcc ccgcgctcga cgagcaggtc
     8221 gacgagcgtc gagccgatga atccctcggc cccggtgacc agcacgctgc ggccggccca
     8281 gtcgccggtg gtgttcaggt cggtgatcat gcgtgattcc tctcgacagc ctggaacgga
     8341 aaagggttga cgggggcgcg gcccgccagg cgcagcaccc atgcggccat gaggtcggcc
     8401 gcgagcgcgt gggtgcccgg gtgcgccgcg gcgcccatcg cggcgagccg gcccggatcg
     8461 caaagcagcg gatcgatcag ggcggcgagc cgttcgccgg tggcctcgcc gtcggggagc
     8521 agcagccccg cgccggcgtc ggagagcacc cgcgcgttgt gcgtctggtg gtcgtggggc
     8581 gcgtgcgggt acgggacgag caccgcgggc atccccacgc tcgacagctc cgccaccgtc
     8641 gccgatcccg cgcggcacac catcacgtcg gcggccgcgt aggcgaggtc cattcggtcg
     8701 aggtagccca ccgcggtggc cacccggtcg ccgccctcgg cggccaggcg ggcccgtacc
     8761 cgctccagcg catccggccc ggtcttgatc accagatgga cgtccggccg cccgcgccac
     8821 cgaagggcca gctgcagcgc cgcctccgtc aggcgcgccg cgcccaggct cccgccgttg
     8881 aacagcacca cccacgcgtc gtccggcacg ccgaaccagc ggcgggcctg tccgcgcagg
     8941 gccgcccgcc cggcccggtc gagccccgcg acatcgctga ccagcggcat gcccaccgtc
     9001 tccgcacgca cggacgtacg cgccggcaag tgctcgcggg tgcggtcgaa ggccagcgcc
     9061 acatgcgggg tgagggtcgc agcgaaacgg ttcgccctgc ccggcaccgc gttcgactcg
     9121 tgcaccagga ccggtcggcg cgccatccgc gcccccagca ccgcgggcgc actgggatag
     9181 ccgcccatgc cgacgacgac ctgcgcaccc tggccctcga tcacgcgctg cgcctgtctg
     9241 ccggagcgca cgaggtcggc ggggagcagg taccggcggg ccccgaggga ggagtcgaag
     9301 gggatcatgt ccacggtgtg gagccggtat cccgcatccg gtatcagacg ggtctccaga
     9361 ccgcgttccg taccgatgaa actgatgacg gcgtgaggca ctgctctgcg gagcgcgtcg
     9421 gcgaccgcca gcccggggta gatgtgcccg ccggtaccgc ctgcgccgat gaccaccgaa
     9481 agggtgtcgt ctgctgtagc catggccgca gcctgacgaa atgctttaag agcaccctaa
     9541 gaaagaaagc cggtcaccgg tggcctgcct ctgttcggca tccgcacttc cggcctgaaa
     9601 tacaatcttc cggtgaacga gaacctgccg ccgtgccccg agtgctccag cgcctacacc
     9661 tacgagatgg gcgtgctcct gatctgcccc gaatgcgggc acgagtggtc gcccgcggcc
     9721 gccgaatccg cggacggtga ccaggagaac gtcatcaggg actcggtcgg caacgtgctc
     9781 gccgacggcg acaccgtcac ggtggtcaag tccctcaagg tcaagggcag cgcgaccggc
     9841 atcaaggccg gcaccaaggt gcgcaacatc cgcctcgtcg acggcgtgga cggccacgac
     9901 atcgactgca agatcgacgg cttcggcgcc atgcagctca agtccggcgt ggtccgcaag
     9961 gcctgaccac accacaactt gctcactgca tgcgtgtgac tcactgcatg cgttgcacat
    10021 tccacagcgg cagtccttcg aagaaggcca ccgcctcctc gcgccagtgg ggccgccagc
    10081 cggaggcttc cgcggcggcc tcctcggcgt agcggcgcat gccggcccgg agcgcgtcgt
    10141 ccacgccgtg ctccagggcg atcttgcgga tgcggtcgac cgtcccggcc gtgcagcggg
    10201 ggtcgccgag cgcggactcc accaggctgc gctccgcggc ggtggcggcg gccaggacgg
    10261 cgcggagggc gtagctgcgg cggcccgacc ggatgtcgga gcccggggac ttcccggtga
    10321 cgctctcgtc gccgaagagg tcgaggtagt cgtcgcgcat ctgcccgctg atgccggccg
    10381 gtgtcgcgta gcggcgcagc cgctcgtcgt gctcggccag gttctcgccg gcggccagca
    10441 gccccagcct cagcggggcg aggatcgagt accgggtggt cttgtactcg cagacggtgt
    10501 gcagcaggtc ctcggacggc agcggctcga agtcgcgttc caggtcggtg atctggcccg
    10561 cgaccgtctc cgcccccgca cgcagctgca cccccagcat ggcctgcttg atctccgcgg
    10621 gggcgtccgc ctccagcagg acgtgcatgg acaggaagga cgcgaggtct cccgccagca
    10681 cggcgaggcc cagcgcggtc ccgtcgtcgc cggggaactc ccggcggtag gcgtagtacg
    10741 tggacgggcc gccgcggcgt acgggcgcgt cgtcgatgat gtcgtcgtgg accaggccgt
    10801 gcgtctggag cagttcgatg ctcagcgcgg cctcctccag gccgggcggc cgctcgtcgg
    10861 tcaccagccg tgccgcctcg tacagcaggg cgacccgcag gcgcttcccg ccgcgcaggg
    10921 agaggtcccg caggagttcc aggcagcggg gggtgaagcg gctgagcgcc ggggtgtcga
    10981 ggttctccgc gagggcgtcg aagtacgcct cgaagcgggt gtcgaaccgg tgccggcagc
    11041 cggcgactcg ccgctgggcg gcggccgcga tcgttttgtc catgggccca ccctttcagc
    11101 aggccggccg gggcggacga gggggcggcc ctatcatctc agtggcccgg cgcccggctg
    11161 ccgaacgccg ggcccaccag cgttctttcg gcgaaaggcc aacggggaat tgcgcaagaa
    11221 aagcaaggtg cgtatatccg ccgtcgcggt gtgtaccgcg gcggcgatcg cggggggtct
    11281 gcagatctcg cccagcgcgt tcggcaccga cgagaaggag ccggaggccg cacgcccggc
    11341 cgtggctccg gcgagcacgg gggcggacgc gtccgccccg gagaacgaat ccgcctcgga
    11401 ggactccggc acctccgaca ccgacgggac gcccttcaag gacggcgtca tgtccctgaa
    11461 cacggcggtg ccgcacgcgc cgagagcggc tgcggccgcc gctgcgccgc cccaggggga
    11521 agggtggaag ctctccggcg cgaccaggat gctgccgacc ggctacacca tcaagttcta
    11581 cgaccagaag tccgtggact ggctggcccg ctacgtccag gcgtcggccg cggacctgca
    11641 gcgcgtcacg agcctgcccg tcaccgtcga caccaggccg gtgggctggg actattcccg
    11701 gcccaagggc gaggtggtca tcggcctcct gaagcgcccg tgcatcccgc ccgcggacaa
    11761 cggcagcaag gggtggaaga tcgtgcgcga cggatcgggg gtcaagaacc tcagctgcgg
    11821 attcaccgcc tcctccgtcc ccgggaccgt gaccagcggg cacgcctaca tcgacacgga
    11881 gttcttcacc gcggacggca aacccctgcc ggcctggggc gagccgtaca tgcgcaacca
    11941 catcagccac gaactcgggc acacgctggg gctgacgcat gcgaatcgca gcgcggcgcg
    12001 gggcgattgc gtcaagggca ccgactccgg cgagaagccg gtcatgtgca cgccgaccta
    12061 tgcgtaccag gacaagcgcg cgggcaccta cgtccagcaa ttcgacgtac agggcctgcg
    12121 tttcctcgcc gccggtgccg gcgcggcgct gtccccgcag ggcagggtga ccgggctcgg
    12181 cggcaagtgc ctcgacgtca agggagggag cgcggccaac ggcacgcaga tccagctctc
    12241 cacgtgcaac ggcgcagtgg cgcagtcatg gatcctgggc aaggacggca cgttccgggc
    12301 gctgggcaaa tgcctggaca acgcgcgcaa cgccggcact gacggcaaca agatcgacct
    12361 ttacgactgc aacgggcagc cgtcgcagcg gtggtcggtc gatgcgaagg gccggatcgt
    12421 gcacgtcgca tcgggcaagg tcctcgacgt gaccggcggc aagaccgccg acggcacgaa
    12481 ggtccagctc ttcacggcga acacgaacaa gcgccaggtc tgggtcaccc cgaagtagca
    12541 tccggcggct ccgccaccgc gtcaggcggg acccggccgc agccgggtcc cgcctgacgg
    12601 ccggctcgca agcgttagtg ctggctgttg aggaagccga tgacgacggc tccccaccag
    12661 cagatctggg agaccagggc agtggctccg ccccaggcca ggaggcgcgg tgcgggcgcg
    12721 gcggacggct gctcggccat gcgcttgttg aggaggcccg cctgcaggcc gttgaggctg
    12781 aggaggagca ccagcaccag cttgacggcg gtgagggtgg aggacgggct ggggtggagc
    12841 agcatgccgc tgaggacgag gcccacgaga ccggcccaga tgggcaggtg cagacggccg
    12901 gcgctgccga gggcctcctg gaggctgcag cggcccgtga tccacagcag gccgtagtag
    12961 tcggcgacga gtacggcgcc gaagccgagg acgaggccgg tgaggtggac gaagagggcg
    13021 gcggtgtgaa gcgtcgcgtc ggccgtcagg tggaaggaga tccacacgca gccggcccag
    13081 accgcgcaca gcatcagcgc ggcaccggcc accgtccacc aggagtcgta caggccgagc
    13141 ggccgtgcgt gacgtgcgcc ggaggtgagg gtgcgggtcg gttcaggcgg gcggacgacg
    13201 gacaggggcg tctcggacgg aagagcagac acgcaattct ccatggcctc gaatgtgtcc
    13261 ggcttgttgc cggaatgaga ccttcttttc tgaatggcag aaatcgatca atgccatcgg
    13321 cgtcccggct ccgtcgactt cttcgacgtg gtgccgggga aagccgggct cggcactcga
    13381 caaacctgaa cactctcgtg gagaaatcgc aagctttgca ggtcacgggc ggaatccgcg
    13441 cctattgatc catatccgtt ccggcctgat tgcaggtaat tcgatcgcgg aatggtgatc
    13501 gctattcttc ggaatgtggg acacggcaca tttcctgagc gcgtgagcgc atggctgcgg
    13561 agtgtgtgag cgcatatgta cggagggctg cgggcccgcc ctcgcggaca ggcccgcagc
    13621 ccccgtggaa tcagcccctc agcggccctt cacatgtgaa gtccgccgat cccgcggggc
    13681 ggtccgacca gaggtcgacc ttgccgaagg agcagttcat gtcggcgaag ttgttggtgc
    13741 ccttcttcgt gcggtcgagg atgaagtagt cgaccgtccc ggacatgtcc ttgaagacca
    13801 ggtcgggact gcccgggctg ttcaggttgg cggtgatgcg gccggtgcag gtgaagcggg
    13861 ggcgttccgg ggcctcattg gtgcggcatt cgggcgtgat gccggtggtg gccttgaagg
    13921 aggcgcggac cgtggcgggg tggcccgcgt ccagcccgcc gacgggccgg aacgacgtgc
    13981 tcggcacgta caggttcttg accttggcga tctgctggtc gaggaaggtg tcgtacgcgc
    14041 gctgcaggcc gccgtcccgg ccgagccggt cccgccaggc gtcgaatccc gcgacgtcgt
    14101 tgtcgcggag gtggccgtac atctccctga gcagcgaggg gtgttcgctc cacaggaact
    14161 cgaagaacgt gccggcgtac gagtagaagc ggaatccgtc ccggtcgtac tccgcgtgca
    14221 gcagctcgta cacgctcatg cgcggcttgg tgccgcccgc cgtgtcgttg atgatgctct
    14281 ggaccaggga cttgcggacc ctgatgccct cgccccgggt ggcgccgtcg aagaactcgg
    14341 ccgtgccctc gtccatcgcc gtggtgcggt cgccctggta ccaggggccc tcgccgaaga
    14401 gcccggggac ggcccagcgg ccgttgaggt agtgcgtgta ctcgtgccgg aacagctcct
    14461 ccagcgtgag cgtggagtcc tgggggacgc gccgctcgta cgtgtagaag gtggcgccgt
    14521 tctcgatgta gatcccgccg ttgttggtgc ccatgcccgt cagcagcggg tggtagacct
    14581 cgtagtcggc gcgcgaggcg tacagcacga tgttgagcgt ggtgttggtg tcgcccgcca
    14641 gcggctgctc ggtgcccagc acccggtgga actgcgcctt gacctgcttg ctcgcgtagt
    14701 agaggcggtc gacggtggcg cggggcaggg ccgtgcggac cttgatgccg ccgttgtcgt
    14761 acgtgtaggt ggacgggaag atgcggcgct cgatgtcggc cttgcacacc ccgtactgct
    14821 tgcaggcgtc gaacgcgatc agccaggtga cgaccttggc ccagggctcg ctgccctcgc
    14881 cgaagttgcc ggtggtggtg gccagcaatc cgccgagggc ggaggtgatc tcgctcctga
    14941 gcgcgtcgat ctggcccatc cgcccgtact ccccgacggc gtcgcgcacc acccaggcgt
    15001 tggacgtgcc cttgaggtgg gtgtagccgg cgaaggcctt gaaggccgcg cggtaggagg
    15061 tgtcggcggc gacggcggcg tggaaggcgg cgtcgtggtt gcccgggtag acgcccaggt
    15121 agttgaggga gagcgcggcg agcgcggcgc cggcccagga ggtgtccttg gcggtgccgg
    15181 ggtgctcggc gtccatggtg gcgaggacgc gcttgatgag cggcagctgg tgctggcgca
    15241 ggcccggggc gctggcggcg tagagggcct cgcgcagggt ctcggcgttg gtgcgggtga
    15301 cgtcgaaggt gtgcgcggcg gtgccgaagg cggacacggc ccggcgcatg gcctccacgg
    15361 tcggtgcgtc ggtgacgtcg atctcggtgc gcgagaagtc gtggtacgcg acggcgtgga
    15421 ggtaggtgaa catctccagc aggtggctgc cgttcttgcc gtcgtgcgcc gcggccaggc
    15481 cctcgatccg gcgggagacc gcctggacgt gcgccctcga catgaccggg gccagccgct
    15541 ggtcccaggt ccacagggtc gtgcgcagac agccgtcggc ggtgacggcc tggtcggcga
    15601 ggaagtcggc gagctgctcg ggagcgaggc gcgtgatgcc gtcgagcgtg cacggaacgg
    15661 cggtgccgcc gagggtggcg cggggcgctg cggccgtggg cttcggcttg gccgtgagag
    15721 cgccggggac gcggccgtcc gtgaggccgc cgggggcggt gggagaagca ctggccggct
    15781 tgggcgcgtt ggccagccgg gtgacctcgt cgaaggggtt gggcgtgggg gtgtcctgcc
    15841 gcacgcccgc cgcgggggcc gcggcggagg gcctgggcgc gggcgagggg gagtccgcgt
    15901 gaacgggctg gacggcggtg gcgcagagcg ccgtggctat ggcggtggtg agcagggatg
    15961 cgcgcagcga tctgcgcagc gatctggagt gggacaccga tgactcctgt gtgggaggtg
    16021 tgggttgagg cgcgcacgtg aagggagcgg gtgcgcgcga caacagggaa aagtgcggag
    16081 acagtggcgc agggggtgat tcaactgccg tctgacaggc ggcgcgtggg ggactgctgc
    16141 tgcgccatgt catgcgtaac gtagtaatgt gaaatggtac tgacaacccc tcagacgcta
    16201 cgggttgtcc gcggccgcga agtggcaggc cacctcacgc gcctcgccgg gcgcggcgac
    16261 ccgcagcagc ggcgcctccg tccggcagat ctcctgcgct ttggggcagc gcgggtggaa
    16321 cgtgcaaccg gacgggggag ccgccgggct cggagggtcg ccgagcaaag tgatccgctc
    16381 gcgcgcccgc tcggcgaccg ggtccggcag cggcaccgcc gagagcaggg cctgcgtgta
    16441 cggatgggcc ggggccgcgt acacccgctc cttgtcgccc acttcgacga tccgccccag
    16501 atacatcacg gccacccggt tgcacacccg cttcaccacc gacaggtcgt gggcgatgaa
    16561 gaggtaggcg agcccgagtt cacgctgcag ccgctccatc agattgacga tctgggcctg
    16621 cacggagacg tccagggccg agaccggttc gtcggcgacg atcagacggg ggcctgtggc
    16681 cagcgcgcgg gcgatgccga tgcgctgtgc ctgaccgccg gagaactcgt gcggatagcg
    16741 gtcgatgtgc tcggggatga gcccggtcat ctccatcagc tccgccgccc gcttgcgcgc
    16801 gccggccgcc gccatgccct gcaccagcag ggggtcggcg atgatgcggg ccacggtctg
    16861 gcgcgggttg agggaggagt gcgggtcctg gaagaccatc tgcaggtcct tgcgcagcgg
    16921 tttgagctcg cgccgcccga gccggctgat gtcacggccg tcgtaggtga tcgacccggt
    16981 ggtcggttcc aggagccgta cgatcatgcg gccggtggtg gacttgccgc agccggactc
    17041 gcccaccaga cccagggtct tgcccgccgc cagatcgaag gagacgccgt cgacggcccg
    17101 gacgggcgcc gagcggcctc cccgccggcc cgggaaggtc atcgtcacgt cccgtacgga
    17161 gagcaggggg acggagggag gggggacgga gggcaggggc gcggtgccgg cggtcatcgg
    17221 gtgcctccct gtacgcgggc agcggtgtgc agggacaggt ggcaggagac caggtgccct
    17281 tgggagggcc ggagctctgg acggacgccg gcgcagtgcg cgcgttccgc aggtgtcgcg
    17341 gccgcggcgc gcgggcagcg cggcgagaac gcgcagcccg gggccgggtc cagcagcgag
    17401 ggagggctgc cggggatggc ccgcaggggc gcgtcgtcgc tgtcgtcgag gcggggcagc
    17461 gaatcgagca gaccgcgggt gtaggggtgg ccggggtcgg cgaacagggt gtcgaccggg
    17521 gcctgttcgg ccgcccgccc gccgtacatc acgagcacct cccgggccac gcgcgcgacg
    17581 acgcccagat cgtgcgtgat catgacgacg gcgagtccgc gctgctcctg caggcgggcg
    17641 atcagctcca ggatctgcgc ctggacggtg acgtcgaggg cggtggtcgg ctcgtccgcg
    17701 atgagcaggt cgggctcgca ggcgagggcc atggcgatca tcacgcgctg gcgcatgccg
    17761 ccggagaact ggtgcgggta ctcacctgcc cgccgcgcgg gctcggggat gccgacctcc
    17821 gcgagcatct ccacggcccg cttgcgggcc gccgcccggc gggagccgaa gtggacccgg
    17881 tggtgctcgg cgatctgctc gccgaccgtg tagtaggggt ggaggctgga gagcgggtcc
    17941 tggaagatca tcgccatgcg gcggccgcgc agccggttga gctcgcgctc gggcaggccg
    18001 ttcagctccc ggccgacgag ggcgatggag ccggtgaccc gggcaccggt gtgcagcccc
    18061 atcacggcca aggacgtgac ggacttgccg gagccggact cgccgacgat gccgagcgtc
    18121 tgcccgcggc gcaccgcgaa gctcagggag tccacggccc gtacgtcccc gtgccgggtg
    18181 gggaaggtga cggtcaggtc cgtgacggac agcaggggct gttcctccga ggcggccggg
    18241 ccggctgggg cggctgggtc ggtcgggacg gcttgggcgg ccatcagtac ctcactcgcg
    18301 ggtcgacgac ggcgtagagc aggtcgacgg ccaggttggc gacgacgatg aaggcggccg
    18361 ccaggagcgt gacgccgagg atgaccggct ggtcgccggt ggacagcgcg ccgtagaaga
    18421 gccgcccgat ccccggcagc ccgaagatcg actcggtgat gacggcgccc gcgagcagcc
    18481 cgcccaggtc catgccgaag agggtgagga tcggcgtcat gcccgcgcgc agcccgtgtt
    18541 tgacgacgac ggtgcgccgc ggcagaccct tggcgcgggc ggtgcggatg tacggctccg
    18601 ccatcgtctc gatcatcgag ctgcggctct ggcgggcgta catggcggcg tagagcacgg
    18661 ccagcgccag ccagggcagg agcaggttgg acgcccagtg cagggggtcg tcgccgagcg
    18721 gtacgtactg cgggtagggc agcagcccgg ccgtgcggat cagcccgtag atgagcatca
    18781 tcgaggtgaa gtagaccggc agcgaggccg cggcgacggc gccgaccatc agggcgcggt
    18841 cggtgaggct gtccttgcgc agggccgcgg tgacgccggc gctcaggccg agcgccagcc
    18901 acagcacggc cgcgcccagc gccagggagg ccgagaccgg caggcggtcc atcagcaggt
    18961 cccagacggc ctcggagttc tcgtaggagt agccgaggca ggggaaggcg cagtgcagcg
    19021 cgtattggcc gctgcccatg gtgcggccgg tgaagatgcc ggtgacgaag tccgcgaact
    19081 gccgccacag cggccggtcc aggcccatgt gggcgcggat cgcctccagg cggtcggtgc
    19141 tgcaggactt gccgcaggcg gcggccgcgg ggtcggaggg caggacgtag aagacggtga
    19201 aggtgacggc ggcgatggcg acgagcacgc cggcgacggc gagcagccgg cgcccgaggt
    19261 agagggtcat gtgcggccgc tcctcgggtc gaggacgtcg cgcagcgcgt cgccgaggag
    19321 ggtgaaggcg agcacggtga ggaacaggca ggtgctcggg atgacgaagt acatgggatc
    19381 cgtgtcgtag aaggcgacgc tctcggcgat catctggccc caggaggggg tgggcgggcg
    19441 gacgccgacg cccaggtagc tcagggccgc ctcggtggcg atcatgccgg ggacgatgag
    19501 ggtggtgtag gcgatgacgg gcccggcgac gccggggagg atgtcgcggg tgaggatgcg
    19561 ccagggcccg gagccgccga cgcgggccgc gtcgacgtac tcgcggtgtc tgagcgagag
    19621 ggtctggccg cgtacgacgc gggcgacgcc gggccagccg aacaggccga tgacggcggt
    19681 catcagcagg atgcggttga cgtccttggc caccgacatc atcgcgatca tgaagatgag
    19741 ggaggggaag gacatggtga ggtccatgag gcgggagagc acggcgtcgg tgcggccgcc
    19801 gaagtagccc gccgtgatgc cggccgccgt cccggcgagg acgacgatcg cggtggcggt
    19861 gagggcgatc agcagcgaca cctgggcgcc gtgcacgacc cgggcgaaca ggtcgcggcc
    19921 ggtgacgggt tcgacgccga gccagtggtc ggcggagata ccgcccagcg ggccgagggg
    19981 acggccgccg aggtaggggt cgacggccgt cttgtcgaac tcctcgggcg accagccggc
    20041 gagcgagctc agcagcgggg cgcccgccgc catgagcagg aagagcgcga cgacggcgag
    20101 ggagaccttg acggcggtgc ggcggcgcag ttcggcgcgg gccagctgcc aggggccgct
    20161 gcccgcgggg acggccgccg gggcggggga ggaggcgggc gtgggcgtgg tggtcatggg
    20221 gtgacggccc tcagtcccgg ctcttggcgg ggtccttgag gccgaccgtg gcgtagtcga
    20281 tctggccgcc gaaggaggtg tgcccgtacg cgcccgcgat gttggtgccc aggaccagcg
    20341 gccaccgccg gacgagcacc gggacggtcg gcgcctgggc gaggatccgc ccgtccagct
    20401 gctgccaggc ctcggcggcc gccttggtgt ccgtcatcgc gccgatctcg tccatccgct
    20461 tcatcgtcgc gtcgtcgcgg aagagggagt ggttgccgga gtttcccttc tccttgatga
    20521 agcggccgtc gaagacgaag ggcaggaagg tggagccgga ggggtagtcg gggcaccagc
    20581 cggtgtagac catgtcggtg cggttctcgg tgtcgccgat ggtggcgtag aaggccgacg
    20641 ggtccacggt ctcgatggtg accttgatgc cggcccggcc cagtgactgc tggacggcct
    20701 cggcccggcc cttgtcgccg gccgatgcgg tgatcttcgt ggagatgccg tcgggcttgc
    20761 ccgcctcctt cagcagctgc ctggccttgt ccgcgtcgcc cgtgacgggg atcttcaggg
    20821 tgtcgggctg cttgccgccg aagagggacg ccggcatgta cgcggtcgac aggtcgttga
    20881 aggccgggcc gccggaggcg gtgaggacgg cgtcccggtc gagggcgtac tgcacggccc
    20941 ggcggacctt ggggtcgtcg aagggcgccc gcccggtgtg catctggacc atgtcggtgc
    21001 agttggtgga ctcggcgagc agccgctccc gcacccgggc gtcgggcagg accttggctg
    21061 cgctctcggg acgcagggcg ccccaggaga cggcggaggc gtcggcgccc tgactggcta
    21121 tcagccggtc gtcgatctgg ttggccttga ggcccatcag gacgaccagt ttgtccgggt
    21181 acgccttgcg gacctcgtcc gtacccgggt cccagtggtc gttgcggacg aggacgagct
    21241 tcttgccgcg cgcgtaggag tcgactttgt acgggccgga ggagaacggc cggttgtcgt
    21301 actgcgggcc cttgtcctgc gcctgcggta cgggggcgaa ggtcggcatg acggtggcgt
    21361 tggggaactc ggcgaagggc ttgcgcagtt cgaagacgat ggtgcggtcg tccggcgtct
    21421 tgacggagtc gaggtgcctg ccctgggcgg ggccccggta gccctcggcg ccggcgaggt
    21481 agcgggcggc gtagtcggcg ccgccgggca ggtcggggga gaaggaccgc tcgacgttgt
    21541 acttgacgtc ctgcgcggtg acgggcgagc cgtcctcgta cttcaccccc tgtttgaggt
    21601 ggaacgtcca cgtcctggcg tcggcggacg gcgtgcccag gtcggtggcc aggtcgggga
    21661 ccagcccgcc gccctgggtc ccgggcgtgg ccttgtacgt caccagggtg cggtagagca
    21721 gccgggtccc gaagtccatg tcgttcatga cccagttgcg ggcggggtcg aggtgggtga
    21781 agtcctggtt ggacagcacc gtcagcgtgc cgcccttctg cggagtgccg ccgatcgccg
    21841 tgccctcgtg ggcggcggcg gggttcttgc cgtccttgcc gccggccgac tgcttcccgc
    21901 cggagcaacc ggccgttccc agggcgaagg aggccgccag cacggcggcc agggcagtac
    21961 acgtgcgctt gttcatcagt ggtcactccg tgaacagtcg aacagccgga cggctgaaat
    22021 gtgacccgta acatagtaat gtgaaattgc actgacaagg cgtcagtcac tccgttaccc
    22081 acctgtgtcc gaggaggagt cccgtgcagg aacccgcagt tgccgcgatc cgtacggtca
    22141 gtcatgacct gccggtttca gccgagttcg aggcgttcat ggcggaaggc tgggcggcga
    22201 cgccgctgcc cgccgacatc cggctgcccg tggcggacct cgccgcagcg cgccgcgcga
    22261 agctgtcggc gcgctttccc ggcgagcggt tgatcgtgcc cgcgggcgag ttcaaggtcc
    22321 gctccaacga ctgcgactac cgcttccgcc cgcacagcgc ctacgcctgg ctgaccgggc
    22381 tcaccggcga ggagcaggcc ggtcacgtgc tggtcctgga gcccgacggc ccgcaccggc
    22441 acgaggcggt gctgtacgtg cggccgcgct cgccgcgcgc cggcgaggag ttctaccgcg
    22501 accgccgcta cggcgagttc tgggtcggcc gccgccccga cctcgccgag gccgagcgcc
    22561 tgaccggcat ccgctgcgtg caccgcgagg actacgaccg gctgccgccg ggccgcgacg
    22621 cctccggcga cgccgagctg gccgccgcct tgagcgagct gcgtctggtc aaggacgcct
    22681 gggaggtcgc gcagctgcag ctggccgtgg accacaccgc cgccgggttc gaggacgtcg
    22741 tacgggcgct gccccgcgcc ctcgcccacc cgcgcggcga gcgctggatc gagggcgtct
    22801 tcggcctgcg cgcccgcgcg gagggcaacg gcccgggcta cgagaccatc gcggcctccg
    22861 gcgcgcacgc atgcgtcctg cactggatac gcaacgacgg ccggctcgac ccccgcgaac
    22921 tcctcctcct ggacgcggga gtcgagaccg acaccctcta cacctccgac atcacccgca
    22981 ccctgccgct gtccggacgc ttctcgcccg tccagcggca ggtctacgaa ctcgtcctcg
    23041 ccgcccagga cgcgggcatg gcggccctca agccgggggc gagcttccgc gacttccacc
    23101 gggccgggat gcgggtcatc gccgaggggc tcgccgagtg gggcgtgctc aagagcgccg
    23161 agggcgactt ccaccgccgg tacaccctgt gcagcagcgg ccacatgctc ggcctggacg
    23221 tccacgactg cgcccaggcg cgggcggacg cctacctcga cggcgtcctg gaggaggggc
    23281 aggtgctcac cgtcgagccc gggctctacc tccagcccga cgacgagacg ctgccggccg
    23341 aactgcgcgg catcggcgtg cggatcgagg acgacctggt catcaccgcc gacggggccc
    23401 ggctgatgtc gcacgcgctg ccccgtacgc ccgacgcggt cgaggcgtgg atgggtgagc
    23461 ttctcggggg ataggccgcg aaataggcgg gggcgtcaac catcaggtac ggaccggctc
    23521 ttggcagcgc gcagtgcaat gtgaaatatt actgacgtgc tcatgagcaa ctcctcctcg
    23581 gacgtcatcg tcgtcggagc gggtgtcgtc ggcgccgcct gcgcctacta cgccgcccgc
    23641 accggcctct ccgtcaccgt ggtcgaccgc ggccccgtcg ccggcgggac cacgggagcc
    23701 ggcgagggaa acctcctggt ctccgacaag gaacccggcc cggagctcga actggccctg
    23761 ctctccacgc ggttgtggca cgagctggcc cgggagctcc cggccgggat cgaatacgag
    23821 gccaagggcg gcctcgtcgt cgcctccgac gcccatgcca tggccgcgct gcggaagttc
    23881 gccgccgccc aggccgaggc cggcgtcacg accgaggaga tcccggccga ccggctgcac
    23941 gaggcggagc cgcacctggc ccccggcctc gggggcggct tccgctatcc gcaggacgcc
    24001 caggtgcagc ccgccctcgc cgcagcccac ctgctgcggg cctccggcgc ccgggtgcgc
    24061 accggcgagg aggtggcggc cgtcctcacc ggcgcgaacg gcgaggtgcg gggcgtccgt
    24121 acgacggccg gcgagctgca cgcccccttc gtcgtcaacg ccgcggggac ctggggcggc
    24181 gaggtggccc ggctcgccgg cggccggctg cccgtcctgc cccgccgggg cttcgtgctc
    24241 gtcaccgaac cgctgccgcg cgtggtgcgg cacaaggtct acgcggccga ctacgtcgcc
    24301 gacgtggcca gcggctcggc ggcgctgcag acctccgcgg tggtcgaggg caccccggcg
    24361 ggcccggtcc tgatcggcgc cagccgcgag cgggtcggct tcgaccgtac cttgtcggtg
    24421 gaggtgctcc ggcgcctcgc tgcccaggcc acggccctgt tcccggtgct ggcaggagtg
    24481 cgggccatgc gcacgtacgc ggggttccgc ccgtatctgc ccgaccacct gcccgccatc
    24541 ggccccgatc cccgcgtccc cgggctgctg cacgcctgcg gccacgaagg cgcggggatc
    24601 gggctcgccc ccgccaccgg cctggccgtc gcccggcagc tgacgggcgg cgaacccccg
    24661 ctcgacctcg gacccttcca ccccggccgc ttcgccgcgg ccgcctgaac cccgggccgc
    24721 ctgaaccccc gccccgcgtc cgcccgttgt cccgaaccgt cccgagagga ggcccgcacg
    24781 tggcccgtac ccccgccgac ctggtcaggg cggagcccga cccgcccttc gagatcacct
    24841 tcgacggccg tacggtcacc gccctgcccg gccagtccgt ggccgccgcc ctgtgggcgg
    24901 cgggcatcct cgcctggcgc accaccaggc acggcggccg cccgcgcggg gccttctgcg
    24961 gcatcgggca gtgctacgac tgcctcgcca ccgtcaacgg cgaacccaac cgccgggcct
    25021 gtctggtgcc cgcccggccc ggggacgcga tcaccaccca ggagggacac ggccatgccg
    25081 ggctcgccgt ctgaaccgta cgacctcgtg gtgatcggcg caggccccgc cggcctcgcc
    25141 ggagccgtga ccgccgcccg gctcggcctg tccgtcgccg tcgtcgacgc cgccgcacag
    25201 accggcggcc agtacttccg ccaccccgcc ccgggcctgg gcgccgcgcg cccgcaggcc
    25261 ctgcaccacg actggcccgc gttcgccgag ctgcgcgggc gcttcgaggc gagcggggcc
    25321 gcgcacttgg ccggacatca tgtgtgggcc gtcacgcggc aggacgaaga aatgtggagc
    25381 gtgcacgcgc tcgtcggcga agacagtggc gcagtcggct ccggcaccgg cagcgccgag
    25441 gtttcgggat cccccagtgg cggcggcacc ggcagtgacg gcgaaggccg cacccatgag
    25501 ggcttcagcg ccgagcgcga gcgccccgta cgcctgcaag cccgcgccgt cctgttcgcc
    25561 accggcgccg gcgagcgcca cctgcccttc ccgggctgga cgctgcccgg cgtcgtcggg
    25621 gccggcggcg cccaggccat gctgaagtcc gggctcgtcc tgcccgggca acgggtcgtc
    25681 gtcgcgggca gcggtccgct cctgctcgcc gtcgcctcgt cgctcgccgc ggccggcgcc
    25741 cacgtgcccg aggtggccga ggcatccggc tacctcggct acgcccgccg gccgcgcgcc
    25801 ctcgcggcca accctcacaa gctcctcgaa gccgccgtcc acggcacggc gctcctgcgc
    25861 caccgcatac cgctgcgcac ccgcagcgcg gtcaccgcag tgcacggcac cgaccgcgtc
    25921 gaggccgtca cggtctcccg gctcgatcgc gactggcggg cgctccccgg cacgggacgc
    25981 cgcatcgcct gcgacgccct ggccgtgggc cacgggctcg caccgcagac cgagctggcc
    26041 accggcctgg gctgtgcgac ccgccgcacg cccgacggca cgcacgccct cgtcctcgac
    26101 ggcctccagg agacctcggt gcccggcctg tgggccgcgg gcgagaccgg cgggaccgga
    26161 ggctggcagc tcgcccggac cgagggcgag ctggcgggca tcgcggtggc cgcccggctg
    26221 cgcgcgctcc ccgccctcac ccgcagccgc cgcgtccggg acctggcccg gcgccgcgac
    26281 cgcatgcgcg ccttcgccga ggccatggtc gccgcccacg cccccggccc cggctggacc
    26341 gcatggctcg acgacgacac cgacgtctgc cgctgcgagg aggtgaccgc cggcagcatc
    26401 cgcgacgccg tcaccgcact cggcgcccgg gacgcccgga ccgtcaagct cctcacccgg
    26461 gcgggcatgg gctggtgcca gggccggatg tgcggcgcgg cggtggcctg cctggcggcg
    26521 tccggtacgg cgcaggggac cgtaccgccg tccgccgacc gcaggccgct cgccgtgccc
    26581 gtacctctcg gggccctggc cgccctgccc gaagaacccg gacacgcctg aaccaccgcc
    26641 cgacccgcac aacgcgcatg tcccacgtca cagagccata gaagggttac cgctatgacc
    26701 gcctcctcct ggacccccga ccgcccctgg cgcggcatca tggtcgccac cgccctcccg
    26761 ctgcgcgcgg acctctccgt cgactacgac gcctacgccg aacacgtccg cacgctcatc
    26821 gagagcggtt gcgacggagt cgtccccaac ggctccctcg gcgaatacca gaccctcacg
    26881 ccggaggagc gcgcccgcgt ggtgcgcacc gcagtcgagg cggcgggcga cggggcgcgg
    26941 gtgatgcccg gcgtcgccgc gtacggcagc gccgaggcgc gccggtgggc cgagcaggcc
    27001 gccgaggcgg gctgcggctc cgtcctgctg ctgccgccga acgcctaccg cgccgacgag
    27061 gaggccgtcc gcgcccacta cacggaggtc gccgcggccg ggataccggt cgtcgcctac
    27121 aacaacccca tcgacaccaa ggtcgacctg acccccgccc tgctggccag gctgcatgcc
    27181 gagggaagca tcgtggccgt caaggagttc accggcgacg tccggcgcgc ctacgagatc
    27241 gccgaactcg cccccgaact cgacctgctg atcggcgcgg acgacgtcct cctcgaactc
    27301 gccgccgccg gagccgtcgg ctggatcgcc ggatacccca acgccttccc caccacctgc
    27361 gccgcgctct accacgccgc cgtcgcaggg gacctgcaga cggcactgcc cctctaccgc
    27421 tcgctgcacc cgctcctgcg ctgggattcg aagaccgagt tcgtccaggc catcaagctc
    27481 tccatggaca tcaccggaca gcacggcggc cccacccgcc cgccgcgctc cccgctcacg
    27541 ggcgagaccg aggccgcggt gcgcgccgcc acggagaagg ccgtcgccga cggacaccac
    27601 tgacctccgc cggcttccgg gccttcctcc gatccttctc tcccgctgat tcctgctgat
    27661 tcccgctgcc gacaggaaag gacatccgtg cgtacccgtc atgtcttcca tgccgtcgac
    27721 tcgcacaccg agggcatgcc cacgcgcgtc atcaccggtg gcgtcggcgt gatacccggc
    27781 gccacgatgg ccgagcgccg gctccacttc atcgagcaca tggaccacct gcgcacgctc
    27841 ctgatgtacg agccgcgcgg ccacgcctcg atgagcggcg cgatcctcca gcctcccacc
    27901 cggcccgacg ccgactacgg agtcctctac atcgaggtct cgggggtgct gccgatgtgc
    27961 gggcacggca ccatcggggt agcgaccgtg ctcgtcgaga ccggcatggt gccggtcagc
    28021 gaaccggtga ccactgtgcg cctcgacacc ccgtccggtc tgatcaccgt cgacgtccag
    28081 gtcgaggacg gtgcggccaa ggccgtcaca ctcatcaacg tgccctcttt ctccgtcggt
    28141 ctcgaccgca aggccgacgt ccccggctac gggacggtca cctacgacct cgccttcggc
    28201 ggcaacttct acgccttcgt cgaactcgac tccctgggac tgcccttcga ccgggcccgc
    28261 aaggacgacc tcctcgccgc cgggctcgcc gtcatggaga cggtcaacgc ctcgccggac
    28321 cggcccgtcc accccgaaca ccccgagatc aacggcctca agcacgtcta cctcgccgcg
    28381 cccggctcgg acgcccggca ctccgtgcat gccatggcca tccaccccgg ctggttcgac
    28441 cgttccccct gcggtacggg cacctccgcc cggatggcac agctgcacgc ccgaggcgcg
    28501 ctcccgctcg accgcgactt cgtcaacgag tccttcatcg gcacgcggtt caccggccgc
    28561 ctggtggggg agacgcaggt cggcggcgtg ccggcggtcg tgcccgccat caccgggcgc
    28621 gcctggatca ccggcaccgc ccagtacttc ctcgacccgg acgacccctt ccccggaggt
    28681 ttcctcctgt gaccgccgcc ccgacctcct tcgcctcgca caacccggcc gacccgtccg
    28741 acaccgtcac cgaggtgccc gcgcccggtg cctccgccgc cgccgaggcc gtcgagcagg
    28801 cccgtgccgc ccagcccggc tggctgcagg ccggcgccgc cgcccggtcc tccgcgctct
    28861 ccgccgtggc cgcggcggtc gaggccgcgt ccggcgaact cgccgccctc gctgtacgcg
    28921 aggtgggcaa gcccctcgcc gaggcgcggg ccgaggtggc ccgcacggcc gcgatctggc
    28981 gctactacgc ccaggccccc tacgagccca ccggcgccgt ccacgagacg gccggcggtc
    29041 ccggcctgct gctgacccgg cgccgcccgc acggcgtcgc cggcctgatc acgccctgga
    29101 acttcccctt cgccatcccg tcctggaagg ccgcgcccgc gctcgcggcc ggcaacaccg
    29161 tcgtcctcaa gcccgcaccc gaggccaccg cgtgcgccct gcgcctggcc gagctcgtcc
    29221 ggcaggccgt gcccgccgag gtgttcacgg tcgtgcccgg cggcgcgacc gagggcggcg
    29281 ccgtcctcgc gaccgccgac gccgtctcct tcaccggctc caccgccgtc ggcagcgcgg
    29341 tcacccgcgc cgccaccgcc cggggcatcc cggtccaggc cgagacgggc gggctcaacg
    29401 cggcgatcgt cctgcccgat gccgacatcg agcgggccgc cgcccacatc gccgcggccc
    29461 tcgccggata cgccgggcag aagtgcaccg cgaccagccg ggtgatcgcc gtcggcacgg
    29521 ccctcgaccc cctgcgcgag gccctcgccg cagccctgcg cgccctgccc gtcggcgacc
    29581 cggccgatgc ggccaccgtg tgcggccccc tcatctcggc ccgggcccgg gaccgattcg
    29641 accaggccct gtccggcgcc tccgtcctcg ccgcgggcgc cgctccggaa ggccccggct
    29701 ggtacgcggc gcccaccgtc gtcgaaaagg tgccggccgg acaccggctg ctcaccgagg
    29761 aggtcttcgg ccctgtcgcc gccctgctgc ccgcggacga cctggcgcac gccgtaagga
    29821 tcagcaactc cgtaccgtac ggcctggtca cgtcggtcca caccggcggg ctcgaagcgg
    29881 cgctgcacgg tctcgaccac ctcgacacgg gcatgatccg cgtcaacgcc ccttccacgg
    29941 gcgtcgactt ccacctgccg ttcggcggca ccaaggcctc cggccacggc ccgcgcgagc
    30001 agggtcgcgc ggcgctggac ttctacacct ccggccggac ctacaccctg gctccctgag
    30061 aacgatgtga cattgtacgc tcgttgatcc gtccaggtac ggaccagccg gggagcgcgg
    30121 ctgcgcacgt accgcggacg cggctgccgg acctcggccg ccgcaccggc gacgaaggga
    30181 acgggacacc atgggccacc tcaagcagcg cactctcatc accgccaccg agcggctgcg
    30241 cgaccaggtc gcccatgccc tgcgggccgc gctcatctcc ggcgaactcc gccccggcga
    30301 ggtctactcc gcgccgcagc tcgcggagga cttcggcatc tccgcgaccc cggtgcgcga
    30361 ggccatgctc gacctcgccc gcgagggcct ggtcgagccg gtccgcaaca agggattccg
    30421 ggtcaccgag gtcaacgagc gcgacctgga ccagtacacc gagatccgca cgctcatcga
    30481 ggtccccacc acgggccgcg tcacgcgcac cgcagcccgc gaggacctcg aagccctccg
    30541 cccggtcgcc gaggagatcg tgcgcgccgc ccgcgaccac gacctcatcg gctacctgga
    30601 ggccgaccgg cagttccacc tcaccctgct ggccctctcc ggcaacgaac gcctcgtcga
    30661 gaccgtcggc gacctgcgca agcgctcgcg cctgtacggg ctgaccgcgc tcgaccagcg
    30721 cggcgagctc atcccctcag ccgaggagca cctcgaaatc ctcgacctga tgctcgcggg
    30781 tgacgccgag ggcgccgagc agtgcatggc acgacacctc ggccacgtgc gctccctgtg
    30841 ggcgaggggc agcgacaagg actcatgacc acgcgccgga ggccggcgcg agaaggaggg
    30901 cggacatgcg cacttcaccc ctgatcgcgg cggtcctcgc cggctgcctg gcggtccccg
    30961 cgacggcgtg ggcgtccccc gcccggcccc cgtccgcgcg cggctgtgcg ctcaagggca
    31021 cgaccggctg gacggacgag ggccatgaca ccgatcccgt ccgcttccgg cgcgccaccg
    31081 gcacacaccg cgtcctgacc ctgttcgccg acttccccga cgcgcaggcc accggcccca
    31141 ccgccccgta cgccgctcac ctcgcccccg ccgccgactg gttacgcacg gcctcctacg
    31201 gccgggcgcg gctggagatc acgccgctgc accgctggat ccggatgccc gcgccctcca
    31261 cttcctacgg cttccagcgc ggcctcacct tcgaggccca cgagcgctac ctgcgcgacg
    31321 cggtcacggc cgccgacccg tacgcggact tctcccgcta cgacatggtc tacgtcgtcc
    31381 ccgtgagaga ggcggccgcg atctccttct ccccgaccta cctcttcgac cccacaacgc
    31441 ccggcgtcac ggccgacggc acccgcatcc gatgggccgt caccttcggg caggacatgt
    31501 ggcgctgggg ccacaaggtc gccgcccacg agaccggcca cgtcttcggc ctgcccgacc
    31561 tctacgcctt cacgggcgag acccaccgcc acgtcggcgg ctgggacctc atgggcaaca
    31621 tcgccggcac c
//
