LOCUS       NZ_BMUT01000011        20927 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces hiroshimensis strain JCM 4586 sequence11, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUT01000011
VERSION     NZ_BMUT01000011.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces hiroshimensis
  ORGANISM  Streptomyces hiroshimensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 332845)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 90X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650335.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:32:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,830
            CDSs (total)                      :: 6,745
            Genes (coding)                    :: 6,620
            CDSs (with protein)               :: 6,620
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 25 of 125
            Pseudo Genes (incomplete)         :: 107 of 125
            Pseudo Genes (internal stop)      :: 4 of 125
            Pseudo Genes (multiple problems)  :: 11 of 125
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 61730
            Orig. end                         :: 82657
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUT01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20927
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20927
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20927
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10927](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10927)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    738..755
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 24.4"
                     /tool="antismash"
     gene            900..1298
                     /locus_tag="IE241_RS23945"
                     /old_locus_tag="GCM10010324_48910"
     CDS             900..1298
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139770.1"
                     /locus_tag="IE241_RS23945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_48910"
                     /product="VOC family protein"
                     /protein_id="WP_190023887.1"
                     /transl_table=11
                     /translation="MLHHLELWVPDLQRAEKSFGWLLGALGYTPHQHWEHGRSWRLGAF
                     YLVVEQSPALAAAAHERCRPGMNHVAFPVESRAAVDALVEAAPEHGWRLMFPGEHPFAG
                     GPAHYAAYLENEDGFEAELVAVAAGETS"
     gene            1387..1923
                     /locus_tag="IE241_RS23950"
                     /old_locus_tag="GCM10010324_48920"
     CDS             1387..1923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514479.1"
                     /locus_tag="IE241_RS23950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_48920"
                     /product="hypothetical protein"
                     /protein_id="WP_190023888.1"
                     /transl_table=11
                     /translation="MLKMNALPDVPRWAVLAAHAVPLVTLPSGLWRIALVAGLPVAEYE
                     GHLGLGEALYVLSLTVVSESLALLTLGLVRSWGEVVPRWIPLLGGRRVRPLAAVVPALL
                     GATALAGLAVWFLCAPYVNPQQGIWQGTPAQDALLAACYVPLLAWPPLLTAVTIAYYRR
                     RTGRSRVTDGAFARV"
     misc_feature    complement(1945..1954)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     misc_feature    1971..1985
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.6"
                     /tool="antismash"
     gene            2055..3782
                     /locus_tag="IE241_RS23955"
                     /old_locus_tag="GCM10010324_48930"
     CDS             2055..3782
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944278.1"
                     /locus_tag="IE241_RS23955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_48930"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_190023889.1"
                     /transl_table=11
                     /translation="MNLDSTAGVVEAARGGDEAAQDQLVAACLPLVYNIVGRALNGHAD
                     VDDVVQETMIRMVGGLPALRDPEGFRSWLVAITMNQIRSHWRKELKDRKDAPSGGLQEV
                     GEAAAPEPDFVEWSIIRLGLQGQRRQAAQATRWLDGDDQVVMALWWQEAAGELSRAEVA
                     AALGRSPQYTAVRVQRTKAQLETARVVVRALATDPRCPELTDVLGDWDGAPGPLWRKRI
                     ARHARGCAECGGHWSALVPAEGLLAGLGLVPVGAALLARVAGAGPGGPMTACAATATAP
                     VTAPGSGATGAPAPVADPAPPGEPATGGGPADLGRLARRAVVAAGVVAVVVGGTLGGPH
                     LFNAAPEGARPQAPGGTVEIVPVTAGGPTPTGPERSGATAVARSDNDGRAPVRASAPAS
                     PPAPAAAATPAATPSALKSPAKPAAGTPATPAAPSAAPAGDTATPRRTPPGDPGADPAE
                     EVVRIVNTERAKAGCGPVRYSAELVAVARRHTDESASRTPAAQWSAFARRIAVPGHHWS
                     SYGVNASAGQSSASAVVSVWMNDPGHRRTILNCAYTELGVGVSFAYDGPRWVQVFAAR"
     gene            3918..5909
                     /locus_tag="IE241_RS23960"
                     /old_locus_tag="GCM10010324_48940"
     CDS             3918..5909
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891101.1"
                     /locus_tag="IE241_RS23960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_48940"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_229899718.1"
                     /transl_table=11
                     /translation="MILGAAAVAAAAGIAFGVMSTGSATSTPGSQPEAANVPAAQPVHK
                     KTPAPLTSTPPADKQRGLVYDGLKPAPKGDRCVGVYSVSRAGLCTHGPDAPPKGVDITK
                     DTPPVAAKAAAPSSLTGDGGQAPSASEALGGAPSVVDARTGGVATAAAAPGPGTPATPQ
                     AGSGSKVVCEGDGSTGNRVQVLYVHAPGRDRFGQYAASFKQWAAETDVIYNASAKETGG
                     ERHVRYVTEADCTVSVLNAELSAGDLQEFGAMNNALAAKGFNRRDRKYMVFADAQVYCG
                     IGTFNGDERPGQDNLSNFGPSYGRTDSGCWGGSTPAHELGHNLGAVNNSAPHTSKAAHC
                     VDEWDIMCYSDAPYYPKMQVLCPERTGDQRLDCGHDDYFHTSPKPGSYLATHWNIANNR
                     FLMAGGGTTNPDPGPTPTRTPDPTRPPSAGPDAQVSQITPNSAVVSWPKASSATGYDLL
                     IDGKKTADVKDTVVRLTGLTPDTAYKVAVAARGADGKASAPGRAASFRTLSADGGSPVR
                     PGTAYVMVNGLTGQAADLWGGSAADGTVAIAYQRHGYANQQWSFENAGGGTLRVKSAQS
                     GKCLELGSGGRAVAGQYVAQQPCRDTAAQKWRLNAAGGGSYVLQPEGSSLVLGISNRWY
                     YGGRLLELQQKNDQGYQNWTLSKAAASS"
     gene            6027..6671
                     /locus_tag="IE241_RS23965"
                     /old_locus_tag="GCM10010324_48950"
     CDS             6027..6671
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS23965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_48950"
                     /product="hypothetical protein"
                     /protein_id="WP_190023890.1"
                     /transl_table=11
                     /translation="MKLRPTMKLRPTTLAPALGCAALLVLGTPGVAAAHGDTIHFAVGG
                     EQQGGHVRTVATWENDHDPVDEPVAGTLTATGPDGRTAGPWQLVAAEGEKGAYTTRESL
                     PQGTWKVVVHCGFPDLGHGEGTVTVAAVAAPGPERSAPAGRSAARQEATEATEAVETTE
                     GASSETRGSSSGTALVVGACAAVAVATAAGVLLLRTRRLRARRPGKPAVTR"
     gene            complement(6744..7889)
                     /locus_tag="IE241_RS23970"
                     /old_locus_tag="GCM10010324_48960"
     CDS             complement(6744..7889)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009948507.1"
                     /locus_tag="IE241_RS23970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_48960"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_190023891.1"
                     /transl_table=11
                     /translation="MDEALLRSLTPSVLGILVRRGADFAAAEDAVQEALVEAVRVWPTD
                     IPRDPKGWLVTVAWRRFLDAARANAARRRREDRVEEEPAPGPAPAVDDTLQLYFLCAHP
                     SLTPASAVALTLRAVGGLTTRQIARAYLVPEATMAQRISRAKRTVSGVRFDRPGDVATV
                     LRVLYLVFNEGYSGDVDLAAEAIRLTRQLAARIDHPEAAGLLALMLLHHARRAARTASD
                     GSLVPLAEQDRGRWDTALIAEGVGILQAALARDRLGEFQAQAAIAALHADAPTAEETDW
                     VQIVEWYDELARLTDSPIVRLNRAVAVGEADGPRAGLEALAALDASLPRHTAVAAYLHE
                     RDGDLATAARLYAEAAHKAPDLAERDHLTRQAARLNARRRR"
     gene            complement(7882..8304)
                     /locus_tag="IE241_RS23975"
                     /old_locus_tag="GCM10010324_48970"
     CDS             complement(7882..8304)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174162.1"
                     /locus_tag="IE241_RS23975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_48970"
                     /product="YciI family protein"
                     /protein_id="WP_190023892.1"
                     /transl_table=11
                     /translation="MAKYLLLKHYRGAPAPVNDVPMDQWTPEEISAHVQYMNDFAARLE
                     KTGEFVDGQALAPEGAWVRYDGEGRPPVTDGPFAETKDLIAGWMVIDVDSYERAVELAG
                     ELSAAPGAGGKPIHEWLEVRPFLGAPPTVPECAFHG"
     gene            complement(8450..9451)
                     /locus_tag="IE241_RS23980"
                     /old_locus_tag="GCM10010324_48980"
     CDS             complement(8450..9451)
                     /NRPS_PKS="Domain: Abhydrolase_1 (31-316). E-value: 1e-30.
                     Score: 99.1. Matches aSDomain:
                     nrpspksdomains_IE241_RS23980_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574863.1"
                     /locus_tag="IE241_RS23980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_48980"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_190023893.1"
                     /sec_met_domain="PF00561 (E-value: 2.3e-25, bitscore: 83.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.4e-19, bitscore:
                     65.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSVEHRFVEVNGVTLHIAEQGRGQEQGQGPLVVLLHGFPECWY
                     SWRHQFGPLAAAGYRVVAVDQRGYGRSDRPEDVGAYSVLHLAGDVIALIHALGEESAVV
                     VGHDWGAPVAWTTALLRPDVVRGVAGLSVPPAPRGPVPPLPALRSLFGDGFYQLYFQEP
                     GVADAELAQDPAATFRRILFSASGDCPATDPPRPWVIPAGGTLLDAMAGPKELPGWFTE
                     EDVAVFVREFSGHGDRAFTGGLNWYRNIDRNWELLAPFHDLRIVVPALYVGGDRDPVRA
                     FPGMDRLLASLEETVPGLRRSVTLPGCGHWTQQERPEEVNAELLGFLSSLGS"
     aSDomain        complement(8504..9358)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE241_RS23980_Abhydrolase_1.1"
                     /evalue="1.00E-30"
                     /label="IE241_RS23980_Abhydrolase_1.1"
                     /locus_tag="IE241_RS23980"
                     /protein_end="316"
                     /protein_start="31"
                     /score="99.1"
                     /tool="antismash"
                     /translation="PLVVLLHGFPECWYSWRHQFGPLAAAGYRVVAVDQRGYGRSDRPE
                     DVGAYSVLHLAGDVIALIHALGEESAVVVGHDWGAPVAWTTALLRPDVVRGVAGLSVPP
                     APRGPVPPLPALRSLFGDGFYQLYFQEPGVADAELAQDPAATFRRILFSASGDCPATDP
                     PRPWVIPAGGTLLDAMAGPKELPGWFTEEDVAVFVREFSGHGDRAFTGGLNWYRNIDRN
                     WELLAPFHDLRIVVPALYVGGDRDPVRAFPGMDRLLASLEETVPGLRRSVTLPGCGHWT
                     QQER"
     gene            complement(9545..9847)
                     /locus_tag="IE241_RS23985"
                     /old_locus_tag="GCM10010324_48990"
     CDS             complement(9545..9847)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004953812.1"
                     /locus_tag="IE241_RS23985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_48990"
                     /product="hypothetical protein"
                     /protein_id="WP_058041490.1"
                     /transl_table=11
                     /translation="MDEEEDRRLRAIAPEISHTTIGLMRTIVGLEPAERVPEEALKVAD
                     RVLAKHGTDGLRVLVMSLSGWMAVGIENVAHLKGQTNEAIIDDIELTCLEANPDG"
     gene            complement(10001..10927)
                     /locus_tag="IE241_RS23990"
                     /old_locus_tag="GCM10010324_49000"
     CDS             complement(10001..10927)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092344.1"
                     /locus_tag="IE241_RS23990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49000"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_190023894.1"
                     /sec_met_domain="phytoene_synt (E-value: 9.9e-27, bitscore:
                     88.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.6e-09,
                     bitscore: 30.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTWDKALDAAGVHDRQLRDDYTRQRALVARYRRHAYVAVRLLL
                     PGAAVPHVIAMTAFMHHTDNVLDGGSTLAERASAYTVWEKDVREALATGRADHPVIRPV
                     LHTVAARPGLAAAVEAFLGAAVTDLDFTGFATEGDYQDYVDAYSLPAFMLVADLLDPGT
                     DPGAFRAACRSYIDGSQRLDFVNDLAEDLEGGRLAIPRETLEQHGVSRSDLESARDTPA
                     VRALLAGQLRRARHDLLAARRLAGLTAPAGRPFVRAMVELEVLTADAAAAKGCGLLRGS
                     ARPSAGAALRVLLGEYGRARAARRRGL"
     gene            11067..11462
                     /locus_tag="IE241_RS23995"
                     /old_locus_tag="GCM10010324_49010"
     CDS             11067..11462
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018889537.1"
                     /locus_tag="IE241_RS23995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49010"
                     /product="hypothetical protein"
                     /protein_id="WP_190023895.1"
                     /transl_table=11
                     /translation="MTPWLLTDIERAVRSSWGADTCTPEYRSQWTPDNPARDQCGVTAM
                     VLNDLLGGELIRGEVRVEGVQTDFHWWNRLGEGVEIDLTREQFTPEEIVTGGLVIPRPP
                     EIKRLREEYELLRGRVLEKLLRGAAAH"
     gene            11570..12391
                     /locus_tag="IE241_RS24000"
                     /old_locus_tag="GCM10010324_49020"
     CDS             11570..12391
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (61-177). E-value: 2.7e-25. Score:
                     80.3. Matches aSDomain: nrpspksdomains_IE241_RS24000_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539582.1"
                     /locus_tag="IE241_RS24000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49020"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_229899720.1"
                     /transl_table=11
                     /translation="MNDEATRSYYDSGDVDAFYDAVWGGEDIHTGIYTRLGEPIADASR
                     RTVERVADRLDGSLGPGSAVIDLGSGYGGTARRLAERFGCRVVALNLSAAQNERHRAVN
                     AERGLAGRVEVVTGSFHDIPFPDGHFDAVCSLEAFCHSTDRPKVLSEAVRVLKPGGALA
                     FTDIMASEGTPAEVLHPAVSRLGVDALATVSFYREHLAGLGLSDIGFDDHTGQLVNHYV
                     RLTEETAARAEELRGRISAAYLGHLQENLPVWVDAARRGRLQWGVLHGRRP"
     aSDomain        11753..12100
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE241_RS24000_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.70E-25"
                     /label="IE241_RS24000_oMT.1"
                     /locus_tag="IE241_RS24000"
                     /protein_end="177"
                     /protein_start="61"
                     /score="80.3"
                     /tool="antismash"
                     /translation="GSAVIDLGSGYGGTARRLAERFGCRVVALNLSAAQNERHRAVNAE
                     RGLAGRVEVVTGSFHDIPFPDGHFDAVCSLEAFCHSTDRPKVLSEAVRVLKPGGALAFT
                     DIMASEGTPAEV"
     gene            12493..13302
                     /locus_tag="IE241_RS24005"
                     /old_locus_tag="GCM10010324_49030"
     CDS             12493..13302
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662062.1"
                     /locus_tag="IE241_RS24005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49030"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_190023896.1"
                     /transl_table=11
                     /translation="MFYCAFKAVVLVPLLRWLFRPRVEGLGRVPQHGAAIVAGNHQSFT
                     DQFLMGVTLRRRISFLAKQEYFTGRGLKGRLAAAFFRGLGAIPVDRSGRGAGQAAVEEG
                     VKVLGRGELLGIFPEGTRSHDGRLYKGKVGVAEMAIRSGAPVVPCAMIGTFEAQPAGRR
                     LPRLVPVTVRFGEPLDFSRYAGMADQRHVLRAVTDEIMYAILKLSEQEYVDVYAVDARA
                     RLSAHGSGEVRAEVLGSTRFAPGPDRPLGEHGAPAGHAAPEEGRTAA"
     gene            complement(13452..13982)
                     /locus_tag="IE241_RS24010"
                     /old_locus_tag="GCM10010324_49040"
     CDS             complement(13452..13982)
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /GO_function="GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138581.1"
                     /locus_tag="IE241_RS24010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49040"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_190023897.1"
                     /transl_table=11
                     /translation="MKIESEIESEIEPETAGQVPETVRGPRTPEIRSGAQRKRDVLERL
                     GRELDIWVASAGADGVPYLVPLCFLWDGEAIWMATRPANPTGRNLREGGRARLALGHTR
                     DVVLIDGDVETHSAQEVPAAAADAFAGRLGWDPRKEGDAYVYFKVLPRAVQAWHEEPEL
                     RGRHLMRDGKWLV"
     gene            14076..14795
                     /locus_tag="IE241_RS24015"
                     /old_locus_tag="GCM10010324_49050"
     CDS             14076..14795
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072643.1"
                     /locus_tag="IE241_RS24015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49050"
                     /product="hypothetical protein"
                     /protein_id="WP_190023898.1"
                     /transl_table=11
                     /translation="MNDDVRNIVLGLVASGISAAAGWFVRTLLWRRRLRRKQTFFGLPA
                     GSECLLVVNQDPSASGWGVARQDAFALLEISALIKECGAHADIVAHDAARQGIGVRTEF
                     CVGGPVSNRRTEAHLRALLPGVEVNATHGGPDGGALTIGGETYRVDKGTAEYVLLARLT
                     GPGGSRPVFLASGQRSVANQAAIRYLARHHRQLAHRHGLDGTFCLLLKVVNSDAYGPDM
                     VELVADVTEATRRGTPS"
     gene            15124..16725
                     /locus_tag="IE241_RS24020"
                     /old_locus_tag="GCM10010324_49060"
     CDS             15124..16725
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983330.1"
                     /locus_tag="IE241_RS24020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49060"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_190023899.1"
                     /transl_table=11
                     /translation="MITVRGADVRAGARLLLSGVSFHIAPGDRIGLVGRNGAGKTTLMR
                     TLAGELRPAAGDITVTGSLGYLPQDAQAADPATVLTDRILSARGLDRAVRALRAAEDAM
                     ARAGGATAQERAMAAYAHAEADFQARGGYAAEAEAARVAAGVGLPARSMGEPLGALSGG
                     QRRRAELARILFAGHGTLLLDEPTNHLDADATAWLRTFLTGHQGGLVLISHDTGLLADT
                     VNRVFHLDAHRTIIDVHNTGWSAYLARRGADERRRTRERANAERKAAALRNQADRMRAN
                     VATAVAAKNMARRADRMLAALEPARRTERTARIRLPEPAPCGRTPLGAVSLAKSYGGRS
                     VLGGVDLAVDRGSRLAVLGLNGAGKTTLLKILAGRETPDGGRVVHGHGLRLGYFAQEHE
                     TLDPALTVRQNLAAAAPHLSDGEARHVLGAFLFGGDDADKPAGVLSGGERTRLALAGLV
                     HSGANVLLLDEPTNNLDPASRDEVLAAVGSYPGALVMVTHDEGAVEALRPDRVLLLPDG
                     TEDLWDEGYLGLVSSA"
     gene            complement(16802..17578)
                     /locus_tag="IE241_RS24025"
                     /old_locus_tag="GCM10010324_49070"
     CDS             complement(16802..17578)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980225.1"
                     /locus_tag="IE241_RS24025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49070"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_190023900.1"
                     /transl_table=11
                     /translation="MSRSDTSRSFDDLVAEAEAAPVAGWDFSWLEGRATEERPSWGYQR
                     TMSERLARADAALDIQTGGGEVLAGARKLPRTMVATESWPPNVAKATKLLHPLGAVVVA
                     DADEPPLPFADEAFDLVTSRHPATVWWEEIARVLRPGGTYLAQHVGPASAFELVEYFLG
                     PQPEEVRRKRHPDDERREAEAAGLGVVDLRAESLRMEFFDVGAVIYFLRKVIWMVPGFT
                     VGRYRDRLRELHERITAEGPFIAHSARFLIEARKPV"
     misc_feature    complement(17729..17744)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.89"
                     /tool="antismash"
     misc_feature    17730..17743
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.73"
                     /tool="antismash"
     gene            17796..18737
                     /locus_tag="IE241_RS24030"
                     /old_locus_tag="GCM10010324_49090"
     CDS             17796..18737
                     /EC_number="3.5.1.28"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472202.1"
                     /locus_tag="IE241_RS24030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49090"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_190023901.1"
                     /transl_table=11
                     /translation="MAWYPGATKMELQPESDDQPAIRPTQFILHSVGAPWTSRRIYAFW
                     HESTNLESHFGLGYGGDLAQYIGTQTRADANYRANLRPDGSGAVSIETASNLEHTDPWT
                     DRQVDRLVEVGVWLHQYHGLPLRVCRSWDEPGYGYHRLFPQWSTGGTACPGDARVGQFH
                     DAVFPAIVARASGRPADPPQPGGAPRTLGEYSDAQTALVPGAWTTLSVGGEALISGAKA
                     YTATVFLTVTVPAGSTLQGRFYHQRADGSRWNGPIVERIATVGASFVDFTHQGSVSEGE
                     TVRFEACYDPPAPGVRDPGTVATSRARGLYWT"
     misc_feature    18171..18173
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18792..19706)
                     /locus_tag="IE241_RS24035"
                     /old_locus_tag="GCM10010324_49100"
     CDS             complement(18792..19706)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963241.1"
                     /locus_tag="IE241_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_49100"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190023902.1"
                     /transl_table=11
                     /translation="MPADSSAAPSAGPSVRPSAHTSDSPGPGLLDRLEGYYDSVPRSTA
                     RAEDFGPLTLFVREGEGWPYYARPSRGPAGSGPVSAADLLRVRARQRELGLPESFEWVA
                     ETTPALRAAAEEAGLTVHEHPLMVLEPGTAPADPVLPEGLAVRLLAPDDPALPSAVALG
                     PLAFSQPGTAVGPTGTEELEAAERLAARDGTADRLAARIRAGLTVLAAAVRGDTALCSG
                     MHQPVGAVTELVGIGTLPAVRRQGLGLAVTAALVADARARGAETVFLSAGDDDVARIYA
                     RAGFRRAGTALIAEPAGPGAPQA"
     misc_feature    complement(19792..19809)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.75"
                     /tool="antismash"
     misc_feature    complement(19888..19897)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(20641..20656)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.17"
                     /tool="antismash"
     misc_feature    20754..20767
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
ORIGIN
        1 ccttctgctc ctccgagccg gacgcgggct cggacgtctc ggccatgcgc acccgcgccg
       61 tctacgacga ggccaaggac gaatgggtcc tcaacgggac gaagacgtgg gcgacgaacg
      121 gcggcatcgc gaacgtccac gtcgtcgtcg cggtcgtcga cccggagctg ggcgcgcgcg
      181 gccacgcctc cttcatcgtg ccgccgggca ccccggggct ctcccagggg cagaagttca
      241 agaagcacgg catccgcgcc tcgcacaccg ccgaggtcgt cctcgacggc gtccgcctgc
      301 ccggccactg cctcctcggc ggcaaggaca agctggacga gcgcctggcc cgcgcccgcg
      361 agcgcgtgcg caccggcggc gcccgtacgc acaacgccgc catggccacc ttcgaggcct
      421 cccggcccac ggtcggcgcc caggccgtcg gcatcgcccg cgccgcgtac gaggtcgcgc
      481 tcgactacgc ccagacgcgc gtccagttcg gccgccccgt catcgacaac cagggtgtcg
      541 ccttccagct cgccgacatg cgcacccgca tcgacgccgc ccggctgctg gtgtggcgcg
      601 cgtcctggat ggccacggcg ggcaagccct tcaccgctgc ggagggctcg atgtccaagc
      661 tcttcgcggg cgagacggcg aaggccgtca cggcccaggc catgcagatc ctcggcggga
      721 acggctatac acgcgagtat ccggtggagc ggatgcaccg ggatgcggcg atctatacga
      781 tcttcgaggg cacgagcgag atccagcggc tggtgatcgc ccgtacgatc tccgacgtgc
      841 cgatccggtg agcccggggc cggccggacc gaccacctga cgacccgggg gcctgcggcg
      901 tgctccatca cctcgaactg tgggtccccg acctgcagcg cgccgagaag agcttcggct
      961 ggctcctcgg cgccctgggc tacacgcccc accagcactg ggagcacggc cgcagctggc
     1021 ggctcggcgc cttctacctc gtcgtcgagc agtcgcccgc gctcgcggcc gccgcccacg
     1081 agcggtgcag gccgggcatg aaccacgtgg ccttccccgt ggagagccgc gcggccgtcg
     1141 acgcgctcgt ggaggcggcc ccggaacacg gctggcggct gatgttcccc ggcgagcacc
     1201 cgttcgcagg gggacccgcc cactacgccg cctacctgga gaacgaagac ggcttcgaag
     1261 ccgaactcgt cgccgtggcg gcgggggaga cctcctgacg gacggccccg ccctccgccg
     1321 tgcggcggag gaggtccgtc ccgcgggcgg acgcggcgca gaggccccgg caccagcatg
     1381 gatcccatgc tgaagatgaa cgccctgccg gacgtgcccc gatgggccgt cctcgcggct
     1441 cacgccgtgc ccctggtcac cctgccctcg gggctgtggc ggatcgcact cgtcgccggg
     1501 ctcccggtcg ccgagtacga gggccacttg ggcctcggcg aggccctcta cgtcctctcg
     1561 ctcaccgtcg tctccgagtc cctcgccctg ctgaccctcg gactcgtacg gtcctggggc
     1621 gaagtcgtgc cgcggtggat cccgttgctg ggcggccgcc gggtgcgccc gctcgcggcg
     1681 gtggtcccgg cgctgctggg tgcgacggca ctggccggcc tcgccgtctg gttcctctgt
     1741 gccccctacg tgaacccgca gcagggcatc tggcagggga ccccggcaca ggacgcgctc
     1801 ctcgccgcct gctacgtgcc tctgctggcc tggcctccgc tcctgacggc cgtgaccatc
     1861 gcctactacc ggcgccggac gggccggagc agggtcacgg acggggcctt tgcccgggtg
     1921 tgagcacccg tcatacccgc cccggcaaaa aagattccgc cgaaccgcag ttttttctgt
     1981 tatccgccgc acgccctcag gtctcccatg cgtaagaccg ccgatgcggt ggagcggaaa
     2041 gaggtgggcg gaacgtgaac ttggacagca cggccggtgt ggtcgaggcg gcgcgcggcg
     2101 gggacgaggc cgcgcaggac cagctggtcg ccgcctgcct gccgctggtc tacaacatcg
     2161 tcggccgcgc cctgaacggg cacgcggacg tcgacgacgt cgtgcaggag accatgatcc
     2221 ggatggtcgg cggcctgccc gcgctgcggg accccgaagg gttccgctcg tggctcgtcg
     2281 cgatcaccat gaaccagata cgcagccact ggcgcaagga gctcaaggac cgcaaggacg
     2341 cgccgtccgg cggcctgcag gaggtcggcg aagccgccgc ccccgagccc gacttcgtcg
     2401 agtggtcgat catccgcctc ggcctgcagg gacagcgcag acaggccgcg caggccacgc
     2461 gctggctcga cggcgacgac caggtcgtca tggccctgtg gtggcaggag gccgcgggcg
     2521 agctgagccg cgccgaggtc gccgcggccc tcggccgctc gccgcagtac accgccgtcc
     2581 gggtccagcg caccaaggcc cagctggaga cggcccgcgt cgtcgtccgg gcgctcgcca
     2641 cggacccgcg ctgcccggag ctcacggacg tcctgggcga ctgggacggc gcgccgggcc
     2701 cgctgtggcg caagcgcatc gcccggcacg cgcggggctg tgcggagtgc ggcggccact
     2761 ggtccgcgct ggtgcccgcg gaagggctgc tcgccggcct cgggctcgtc ccggtcgggg
     2821 ccgccctgct cgcccgggtg gccggggcgg ggccgggcgg gcccatgacg gcctgtgccg
     2881 ccaccgcgac cgctcccgtg accgctcccg gcagcggcgc taccggggcc ccggcgcccg
     2941 tggcggatcc cgccccgccc ggggagccgg cgacgggcgg cggccccgcc gacctcgggc
     3001 gcctggcgcg ccgggccgtc gtcgccgccg gtgtcgtggc cgtcgtcgtg ggcggcaccc
     3061 tgggcggccc gcacctcttc aacgccgcgc cggagggcgc ccggccgcag gcgcccggcg
     3121 gcacggtcga gatcgtcccg gtcaccgcgg gcggccccac gccgaccggt cctgaacgct
     3181 ccggcgccac ggccgtcgcc cggtccgaca acgacggccg cgctcccgtg cgcgcctccg
     3241 cccccgcctc gccgccggcc ccggcagccg ccgcgactcc cgccgcgacg ccctccgcgc
     3301 tcaagagccc ggccaagccc gcggccggga cacccgccac cccggccgcc ccgagcgcgg
     3361 cccccgcggg agacaccgcc acgccccggc ggacgccgcc gggcgacccg ggtgcggacc
     3421 ccgccgagga ggtcgtccgc atcgtcaaca ccgaacgcgc caaggccgga tgcggccccg
     3481 tgcgctacag cgccgaactc gtcgccgtcg cccgtcgcca caccgacgag agcgcgtcgc
     3541 gcacccccgc cgcccagtgg tccgccttcg cccgccggat cgccgtcccc ggccaccact
     3601 ggagctcgta cggggtgaac gcctccgccg ggcagagcag cgcctccgcc gtcgtgtccg
     3661 tgtggatgaa cgaccccgga caccgccgga ccatcctcaa ctgcgcctac acggagctgg
     3721 gcgtcggcgt ctccttcgcc tacgacggcc cgcgctgggt gcaggtcttc gcggcgcgct
     3781 gagcgcggcc acccttcgag ccacccccct cgccgggcgg gccagcgccg cgcccggccg
     3841 ttccgtaacc cccaccgatg ggaactccct tgccacgcaa acacagtcac cgccgccgca
     3901 gcagaaccgg tcgccgcgtg atactcgggg cggccgcggt cgccgcggcc gccggaatcg
     3961 ccttcggcgt catgagcacc ggttccgcga cgtccacccc gggctcgcag ccggaggcgg
     4021 cgaacgtgcc cgccgcgcag ccggtgcaca agaagacgcc cgcccccctc acctcgacgc
     4081 ccccggccga caagcagcgc ggcctcgtct acgacggcct caagcccgcc cccaagggcg
     4141 accgctgcgt cggcgtctac agcgtctcgc gggccggcct gtgcacccac ggccccgacg
     4201 ccccgcccaa gggcgtcgac atcaccaagg acaccccgcc cgtggcggcg aaggcggccg
     4261 ctccctcctc cctgaccggt gacggcggcc aggccccctc ggcctccgag gccctcggcg
     4321 gagcaccgtc cgtggtcgac gcccgcacgg gcggcgtggc cacggccgcc gccgccccgg
     4381 gccccggcac gcccgcgacc ccgcaggccg gctccggctc caaggtcgtc tgcgagggcg
     4441 acgggtcgac cggcaaccgc gtccaggtgc tgtacgtcca cgcgcccggc cgcgaccggt
     4501 tcgggcagta cgccgcctcc ttcaagcagt gggcggccga gaccgacgtc atctacaacg
     4561 cgagcgccaa ggagaccggc ggcgagcggc acgtccgcta cgtcaccgag gccgactgca
     4621 ccgtctccgt cctgaacgcc gagctctccg cgggcgacct gcaggagttc ggggccatga
     4681 acaacgccct ggccgccaag ggcttcaacc gccgcgaccg caagtacatg gtcttcgccg
     4741 acgcccaggt ctactgcggc atcggcacct tcaacggcga cgagcggccc ggccaggaca
     4801 acctcagcaa cttcggcccc tcctacggcc gtacggactc cggctgctgg ggcggcagca
     4861 cccccgccca cgaactgggc cacaacctcg gcgcggtcaa caacagcgcc ccgcacacca
     4921 gcaaggccgc gcactgcgtc gacgagtggg acatcatgtg ctactcggac gccccgtact
     4981 accccaagat gcaggtcctg tgccccgagc gcacggggga ccagcggctg gactgcggtc
     5041 acgacgacta cttccacacc tcccccaagc cgggcagcta cctggccacc cactggaaca
     5101 tcgcgaacaa ccgcttcctg atggccggcg gcggcaccac gaaccccgac cccggcccca
     5161 cgccgacccg tacgcccgac ccgacgcggc cgccgtccgc cgggcccgac gcccaggtca
     5221 gccagatcac cccgaactcc gccgtcgtca gctggccgaa ggcgtcctcg gccaccggct
     5281 acgacctgct gatcgacggg aagaagacgg ccgacgtcaa ggacaccgtc gtccgcctca
     5341 ccggactcac ccccgacacc gcctacaagg tcgccgtcgc cgcccgcggc gccgacggca
     5401 aggcctccgc gccgggccgg gccgcgtcct tccgcaccct ctccgccgac ggcggctcgc
     5461 cggtccggcc gggcaccgcg tacgtgatgg tcaacggcct caccggccag gccgccgacc
     5521 tgtggggcgg ctccgcggcg gacggcaccg tcgccatcgc ctaccagcgc cacggctacg
     5581 ccaaccagca gtggtccttc gagaacgcgg gcggcggcac gctgcgcgtg aagtcggccc
     5641 agagcggcaa gtgcctcgaa ctgggcagcg ggggacgggc cgtggccggc cagtacgtcg
     5701 cccagcagcc ctgccgtgac accgccgcgc agaagtggcg gctgaacgcc gccggcggcg
     5761 ggtcgtacgt cctgcagccc gagggctcgt ccctggtgct gggcatcagc aaccgctggt
     5821 actacggcgg ccggctgctc gaactccagc agaagaacga ccagggctac cagaactgga
     5881 ccctgtcgaa ggccgccgcc tcctcctgac ggccgccctc cgaccgggcc ggcgaccgct
     5941 gcttcacccc ctgccttccc ccaccggcgg tcgccggccc ggccccttct gccctgctcc
     6001 tcccaccctc ttgaggaacc gtcacgatga agctgcgccc cacgatgaag ctgcgcccca
     6061 ccaccctcgc accggcgctc ggatgcgccg ccctgctcgt cctgggtacg cccggagtgg
     6121 ccgccgcaca cggcgacacc atccacttcg ccgtgggcgg agagcagcag ggcggccacg
     6181 tacggaccgt ggcgacctgg gagaacgacc acgaccccgt ggacgagccg gtcgcgggca
     6241 ccctgacggc caccggcccg gacggacgca ccgccggtcc gtggcagctc gtggccgccg
     6301 agggcgagaa gggggcctac accacccgcg agtccctgcc gcagggcacc tggaaggtcg
     6361 tcgtccactg cggcttcccg gacctcggcc acggggaggg gacggtcacg gtcgcggccg
     6421 tggccgcacc cgggccggag cggtcggcgc ctgcaggccg gtcggccgcc cggcaggaag
     6481 cgacggaagc gacggaagcg gtggaaacga cggaaggtgc gtcctcggag acccgggggt
     6541 cctcctccgg tacggccctc gtcgtgggtg cctgcgcggc cgtcgccgtg gcgacggccg
     6601 ccggggtgct cctgctgcgg acgcgccggt tgcgtgcccg ccgaccgggg aagcccgccg
     6661 tcaccaggtg agcagcggcc tcacggggtg aggaccagcc ggatcgggtc gcccgtcccg
     6721 gtgagggtcg cctacttgac ccgtcagcgg cgtcggcggg cgttgagccg ggcggcctgg
     6781 cgtgtcaggt ggtcgcgctc ggcgaggtcg ggtgccttgt gggccgcctc ggcgtacagc
     6841 cgtgccgccg tcgccaggtc gccgtcgcgc tcgtggaggt acgccgccac cgcggtgtgg
     6901 cggggcaggg aggcgtccag cgccgcgagc gcctccaggc cggcgcgcgg tccgtcggcc
     6961 tccccgacgg cgaccgcgcg gttgagccgg acgatggggc tgtcggtcag gcgcgcgagc
     7021 tcgtcgtacc actcgacgat ctgcacccag tcggtctctt cggcggtggg cgcgtcggcg
     7081 tggagtgccg cgatggcggc ctgggcctgg aactcgccca gccggtcgcg ggcgagggcc
     7141 gcctggagga tcccgacgcc ctcggcgatc agcgcggtgt cccaccggcc gcggtcctgc
     7201 tcggcgagcg gcaccaggct gccgtcggat gcggtgcggg cggcacgccg ggcgtggtgg
     7261 agcagcatga gggcgagcag cccggccgcc tcggggtggt cgatgcgggc cgcgagctgc
     7321 cgggtgagcc ggatggcctc ggcggcgagg tcgacgtcgc cggagtagcc ctcgttgaag
     7381 acgaggtaga ggacgcgcag cacggtggcg acgtcgccgg gccggtcgaa gcgcacgccg
     7441 gagaccgtgc gcttggcccg gctgatccgc tgcgccatgg tcgcctcggg caccaggtag
     7501 gcccgggcga tctggcgggt ggtcagcccg ccgacggcgc gcagcgtgag cgcgaccgcc
     7561 gacgccgggg tcagcgacgg gtgggcgcac aggaagtaga gctggagcgt gtcgtccacc
     7621 gcgggcgcgg gcccgggcgc cggctcctcc tcgacgcggt cctcacgccg gcggcgggcg
     7681 gcgttcgccc gggccgcgtc gaggaaccgg cgccaggcca cggtgaccag ccagcccttg
     7741 gggtccctcg gtatgtccgt cggccagacg cgaaccgcct cgaccagcgc ctcctgcacg
     7801 gcgtcctcgg ccgccgcgaa gtcggctccg cggcggacga ggatcccgag cacgctcggc
     7861 gtgaggctgc ggagcagggc ctcatccatg gaaggcgcac tccgggacgg tgggcggcgc
     7921 gcccaggaac gggcgcacct ccagccactc gtgaatcggc ttcccacccg ccccgggggc
     7981 ggccgacagc tccccggcca gctcgacggc acgctcgtag ctgtcgacgt cgatgaccat
     8041 ccagccggcg atcaggtcct tggtctcggc gaacggtccg tcggtgaccg gagggcgccc
     8101 ctcaccgtcg tagcggaccc acgctccctc gggggcgagc gcctgaccgt cgacgaactc
     8161 gcctgtcttc tccagccggg ccgcgaagtc gttcatgtac tgcacatgcg ccgagatctc
     8221 ctccggggtc cactggtcca tcggcacgtc gttgaccgga gccggggcgc cgcggtagtg
     8281 cttcaacagc aggtacttgg ccatcgtgat tctcctcggt gctcgtgcga cccaattgtg
     8341 gtcgcgttca ccccgggggc ggagccggac gcgggttctc gacatcgtcg tccgattttt
     8401 ttggctcttg tggatgagcc cccgcggacc ccttcgccct gcatgaaggc tacgagccca
     8461 gggacgacag gaaccccagg agctcggcgt tgacttcctc agggcgctcc tgctgcgtcc
     8521 agtgaccgca gcccggcagg gtcacgctgc ggcgcagccc cggcaccgtc tcctccaggg
     8581 acgccaggag ccggtccatg ccggggaagg cccggacggg gtcgcggtcg ccgcccacgt
     8641 acagcgcggg gacgacgatg cggaggtcgt ggaagggggc caggagctcc cagttccggt
     8701 cgatgttgcg gtaccagttc aggccgccgg tgaaggcgcg gtcgccgtgc ccggagaact
     8761 cgcggacgaa gacggccacg tcctcctcgg tgaaccagcc cggcagttcc ttcggccccg
     8821 ccatcgcgtc caggagcgtc ccgccggccg ggatcaccca cgggcgcggc gggtcggtcg
     8881 ccgggcagtc gcccgaggcg ctgaacagga tccggcggaa cgtcgccgcc gggtcctgcg
     8941 ccaactcggc gtcggcgacg cccggttcct ggaagtagag ctggtagaag ccgtcgccga
     9001 acagggagcg cagcgcaggc agaggcggca ccgggccgcg cggcgccggc ggcacgctca
     9061 ggcccgccac gccgcggacg acgtcgggcc gcagcagcgc cgtggtccag gcgaccggcg
     9121 cgccccagtc gtgcccgacg accaccgcgc tctcctcgcc gagggcgtgg atcagggcga
     9181 tcacgtcacc ggcgaggtgg agcacgctgt acgcgccgac gtcctccggc cggtcgctgc
     9241 gcccgtaccc gcgctggtcc actgccacga cccggtaccc ggctgcggcc agcggcccga
     9301 actggtgccg ccaggagtac cagcactccg ggaagccgtg cagcaggacg accagcggcc
     9361 cctgcccctg ctcctgcccc cgcccctgct cggcgatgtg cagggttact ccgttgacct
     9421 cgacgaagcg gtgctcgacc gagctggtca tggtgtcctc ccggggggcg tcacgccgac
     9481 gtactccaca gtaggcgtca acttccccgc agcgaaggag acgtcgacca ctcggtcggc
     9541 cgcttcagcc gtcggggttg gcctccagac aggtcagctc gatgtcgtcg atgatggcct
     9601 cgttcgtctg gcccttcagg tgcgcgacgt tctcgatgcc gaccgccatc caccccgaca
     9661 ggctcatgac gagcacccgc agcccgtccg taccgtgctt ggcgagcacc cggtccgcca
     9721 ccttgagcgc ctcctccggc acccgttccg ccggttcgag gccgacgatg gtgcgcatca
     9781 gcccgatggt ggtgtgcgag atctccggcg cgatcgcccg cagcctccgg tcctcttcct
     9841 cgtccacgtg tcctcgattc gtccgtcaga cggtcacgtg caagcaccct aggcggccgt
     9901 gcgcgggcac cgcagcccga acaccaacgg gtgatcgctg ctacgggtga atcgcggtca
     9961 agaagctccc aagtcacccc cgaggatgct cgaagcgccc tcagaggccg cgccgccgag
    10021 cggcccgtgc acggccgtac tccccgagga gcacccgcag ggccgcaccg gccgaagggc
    10081 gcgccgaccc ccgcaacagg ccgcagccct tcgccgccgc ggcgtccgcg gtgagcactt
    10141 ccagctccac catcgcgcgc acgaacggac ggccggccgg tgcggtgagg ccggccaggc
    10201 ggcgcgcggc cagcaggtca tggcgcgcgc ggcgcagctg accggccagg agcgcccgca
    10261 cggccggagt gtcgcgtgcc gattccaggt cgctacggga gacgccgtgc tgctccaggg
    10321 tctcccgggg aatggccagg cgcccgccct ccaggtcctc ggcgaggtcg ttgacgaagt
    10381 ccaggcgctg gctgccgtcg atgtacgaac ggcaggccgc acggaacgcg cccgggtcgg
    10441 tgcccgggtc gagcaggtcg gcgacgagca tgaacgccgg cagcgagtag gcgtcgacgt
    10501 agtcctggta gtcgccttcc gtcgcgaacc cggtgaaatc cagatcggtc actgcggccc
    10561 ccaggaaggc ctcgaccgct gcggcgagcc cggggcgggc ggcgaccgtg tggagcaccg
    10621 gccggatcac cggatggtcc gcgcgcccgg tggccagggc ctcgcgtacg tccttctccc
    10681 acacggtgta ggcggaggcg cgctcggcca gggtgctgcc gccgtcgagc acgttgtccg
    10741 tgtggtgcat gaaggcggtc atggcgatga catgcgggac ggccgcaccg ggcagcagca
    10801 gccggacggc cacgtaggcg tggcgccggt agcgcgcgac gagggcgcgc tgccgggtgt
    10861 agtcgtcgcg cagttgccgg tcatggacgc cggcggcgtc cagcgccttg tcccacgtgc
    10921 tcgtcatgga tcccttttcc cgtccgctgg ttccggccgc tgcgggccac ggaggactgt
    10981 acgtcgtacg tcgtacgtct cgcggacggg gaccgggagg gtgctgccgc ggtgcgttgt
    11041 cagtggtcgc tgtcaggatg cagggcatga caccgtggct tctcaccgac atcgagcgtg
    11101 ccgtccgcag cagttggggc gccgacacgt gcacccctga gtaccggtcg cagtggacac
    11161 cggacaatcc ggcgcgcgat cagtgcggcg tcaccgcgat ggtcctcaac gacctgctgg
    11221 gcggcgagct catccggggg gaggtccgtg tcgaaggcgt acagaccgac ttccactggt
    11281 ggaaccggct cggggagggt gtggagatcg acctgacccg cgagcagttc acccccgaag
    11341 agatcgtcac gggcggcctg gtcataccgc ggccccccga gatcaagcgc ctccgcgagg
    11401 agtacgagct tctgcgcgga cgcgttctgg agaagctgct gcggggcgcg gctgcgcact
    11461 aggcgcgcgg gggcgggcgc tgcccgatca tggcttgttc gtccctgtgt tcgccgtcgc
    11521 acagcagtga ggctgatctt gaccgatcct gcgggcgaga ggagcactcg tgaacgacga
    11581 agcgacgcgc agctactacg actccggcga tgtcgacgcc ttctacgacg cggtctgggg
    11641 cggggaggac atccacaccg gcatctacac ccggctcggc gaacccatcg ccgacgcctc
    11701 ccgccgcacc gtcgagcggg tcgcggaccg gctcgacggc agcctcgggc ccggcagcgc
    11761 cgtcatcgac ctcggttccg gatacggggg gaccgcccgc aggctcgccg agcgcttcgg
    11821 ctgccgcgtc gtcgccctga acctcagcgc cgcccagaac gagcggcacc gcgcggtcaa
    11881 cgccgagcgc ggcctggccg gccgcgtcga ggtcgtcacc ggctccttcc acgacatacc
    11941 gttccccgac ggccacttcg acgcggtgtg ctccctggag gccttctgcc acagcactga
    12001 ccggccgaag gtgctgagcg aggcggtccg ggtgctcaag cccgggggcg cgctggcctt
    12061 caccgacatc atggcctccg aaggcacgcc cgcggaggtg ctccacccgg ccgtctcccg
    12121 gctcggcgtg gacgccctgg ccaccgtgtc cttctaccgc gagcacctcg ccggcctcgg
    12181 cctgtccgat atcggattcg acgaccacac cggtcaactg gtcaaccatt atgtccggct
    12241 gaccgaggag acggcggcgc gcgcggagga gctccgcggg cgcatcagcg ccgcctacct
    12301 cggccacctg caggagaacc tgcccgtatg ggtcgacgcc gcacgccgag gacggctgca
    12361 gtggggcgtc ctgcacgggc gccgtccgta atcaatcagc cacgctctgg ctcaatcggc
    12421 cttctccccc tgatccatac ccgcgagtag cgtgcccggg cgcggggggc tctctgggag
    12481 aagggcgttt gcatgttcta ttgcgcgttc aaggccgtgg tgctcgtgcc gctgctgcgg
    12541 tggctcttcc ggccgagggt ggaggggctg ggccgggtcc cgcagcacgg cgcggcgatc
    12601 gtcgcgggga accaccagtc gttcaccgac cagttcctga tgggcgtgac cctcaggcgc
    12661 cggatcagct tcctcgccaa gcaggagtac ttcaccggcc gcggcctcaa gggcaggctc
    12721 gccgccgcct tcttccgcgg gctcggcgcg atacccgtcg accgctccgg ccgcggcgcg
    12781 ggccaggccg ccgtcgagga gggcgtgaag gtgctcggcc gcggcgaact cctcggcatc
    12841 ttccccgagg gcacgcgctc gcacgacggc cggctgtaca agggcaaggt cggggtcgcg
    12901 gagatggcga tccggtccgg cgcgcccgtc gtcccgtgcg cgatgatcgg cacgttcgag
    12961 gcccagcccg cggggcggcg gctgccgcgc ctggtgcccg tcaccgtccg cttcggcgaa
    13021 cccctggact tctcccgcta cgcgggcatg gcggaccagc ggcacgtgct ccgcgcggtc
    13081 accgacgaga tcatgtacgc gatcctgaag ctgtcggagc aggagtacgt cgacgtgtac
    13141 gccgtcgatg ccagggcccg gctgagcgcc cacggctccg gcgaggtccg cgccgaggtc
    13201 ctggggagca cacggttcgc gccgggcccg gaccgcccgc tcggcgaaca cggagctccg
    13261 gccgggcacg cggctccgga agaagggcgc accgcggcgt agcgggagcg cgaggaggac
    13321 ggagggggca cccgtgggga cgggcgcacc gggcggccgg cggcagctcc gccggaccgc
    13381 ccggcagtgc cctccggcac acactcgccc gtcgcccgga cgaaccaccc gccgcccccg
    13441 tcgcccgtcg ctcagaccag ccacttcccg tcacgcatca agtgacggcc acggagctcg
    13501 ggctcctcgt gccacgcctg cacggcacgc ggcagcacct tgaagtagac gtacgcgtca
    13561 ccctccttgc gggggtccca gcccaagcgc ccggcgaacg cgtcggccgc cgcggccggc
    13621 acctcctgcg cgctgtgggt ctccacgtcg ccgtcgatga ggacgacgtc gcgcgtgtgc
    13681 ccgagggcga gccgggcccg gccgccctcc cgcaggttgc ggcccgtcgg gttggccggc
    13741 cgggtagcca tccagatcgc ctccccgtcc cacaggaagc acaacggcac caggtacggc
    13801 actccgtcgg cgccggccga ggcgacccag atgtccagct cccggcccag ccgctccagg
    13861 acgtcccgct tgcgctgcgc tccactgcgg atctccgggg tccgcgggcc ccggaccgtt
    13921 tccgggacct gtccggccgt ctccggttcg atctccgatt cgatctccga ttcgatcttc
    13981 atgcccggac gctacaggcg cgggctcccg tgcgcctcgg gccgcggccg tagggccgtc
    14041 gaccgacccc gcccgggccc gtaggctgcc cgctcatgaa cgacgacgtg cgcaacatcg
    14101 tgctgggcct ggtcgccagc gggatcagcg ctgccgcggg ctggttcgtc cggacgctcc
    14161 tgtggcggcg ccgactccgg cgcaagcaaa ccttcttcgg cctgccggcg ggctccgagt
    14221 gcctgctcgt ggtcaaccag gacccgagcg cgagcggctg gggcgtcgcg cggcaggacg
    14281 ccttcgcgct gctggagata tccgcgctga tcaaggagtg cggggcgcac gcggacatcg
    14341 tggcgcacga cgccgcccgc caggggatcg gcgtgcgcac cgagttctgc gtcggcgggc
    14401 ccgtgtcgaa ccggcgcacc gaggcccacc tgcgcgcgct gctgcccggc gtcgaggtga
    14461 acgccacgca cgggggcccc gacgggggtg cactcaccat cggcggcgag acataccggg
    14521 tcgacaaggg cacggccgag tacgtcctgc tcgcccggct gaccgggccg ggcggcagcc
    14581 ggccggtctt cctcgcctcc ggccagcgca gcgtcgccaa ccaggcggcc ataaggtatc
    14641 tggcccggca ccacaggcag ctcgcccacc gccacgggct cgacggcacc ttctgcctcc
    14701 tgctgaaggt cgtgaactcg gacgcgtacg gaccggacat ggtggaactg gtcgccgacg
    14761 tcaccgaggc gactcgtcgg ggaacacctt cgtgaccacc ttgccgtcgg ccgccagata
    14821 gccgtagagc atcccctctc cagcgaccgt acggccgcct cgaccgcggc cacgctgccg
    14881 ccgccgtccc gcaggacctt ccggccggcg cggagggcgc cggccagcgg cggcgcggac
    14941 ggttgcgaca gcgagggaag cgccaccgcg acggcgtcat ccggatgcca cgccgaaatc
    15001 cggatgcgca cgccgcactc gcgcggctac cctcgcccgc atgtctacgc cccgcatttc
    15061 ctagctcaag gacccgattc cacgccaccc gtgtgtcctt gagcttttcc ggagcgtaat
    15121 tacatgatca ccgttcgcgg tgccgacgtc cgtgccggcg cccgtctcct gctgtccggc
    15181 gtctccttcc acatcgcccc cggcgaccgc atcggcctgg tcggccgcaa cggcgcgggc
    15241 aagacgaccc tgatgaggac cctggccggc gaactccggc ccgccgccgg agacatcacc
    15301 gtcaccggct ccctcggcta cctcccgcag gatgcgcaag ccgccgaccc ggccaccgtc
    15361 ctcaccgacc ggatcctctc cgcccgcggc ctggaccggg ccgtccgtgc cctgcgggcc
    15421 gccgaagacg ccatggcccg ggccggcgga gcgaccgccc aggaacgggc catggccgcg
    15481 tacgcccacg cggaggccga cttccaggcc cgcggcgggt acgcggccga ggccgaggcc
    15541 gcccgagtcg cggccggcgt ggggctgccc gcccgcagca tgggcgaacc gctgggcgcc
    15601 ctgtccggcg ggcagcggcg gcgggccgag ctggcccgca tcctcttcgc cggccacggc
    15661 accctgctgc tcgacgagcc gaccaaccac ctggacgccg acgcgaccgc ctggctgcgt
    15721 accttcctga cgggccatca aggcgggctg gtgctcatca gccacgacac cggcctgctg
    15781 gccgacaccg tcaaccgcgt cttccacctc gacgcgcacc gcaccatcat cgacgtccac
    15841 aacaccggct ggagcgcgta cctggcccgg cgcggggccg acgaacggcg ccgcacccgg
    15901 gagcgggcga acgccgagcg caaggcggcc gcgctgcgca accaggcgga ccggatgcgg
    15961 gcgaacgtcg ccaccgccgt cgcggcgaag aacatggccc gccgcgccga caggatgctc
    16021 gccgccctcg aaccggcccg ccggacggag cggaccgcca ggatccggct gcccgaaccc
    16081 gccccctgcg ggcgcacgcc cctcggagcc gtcagcctcg ccaagtccta cggcggccgg
    16141 agcgtcctcg gcggcgtcga cctcgccgtc gaccgcggca gccgcctcgc cgtcctcggc
    16201 ctcaacggcg ccggcaaaac caccctgctg aagatcctcg ccgggcgcga gacacccgat
    16261 ggcggccgcg tcgtccacgg ccacggcctg cgcctcggct acttcgccca ggagcacgag
    16321 accctcgacc ccgcgctgac ggtgcggcag aacctggccg cggccgctcc ccacctgagc
    16381 gacggggagg cccggcacgt cctcggagcg ttcctgttcg gcggtgacga cgccgacaag
    16441 ccggccggag tgctctccgg aggcgagcgg accaggctgg ccctggccgg cctggtgcac
    16501 tccggtgcca atgtgctgct gctggacgag ccgaccaaca acctcgaccc ggcctcgcgc
    16561 gacgaggtcc tcgcggcggt cggctcctac cccggcgctc tggtgatggt cacgcatgac
    16621 gagggtgccg tggaggcgct gcgcccggac cgggtcctcc tgctgccgga cggcacggag
    16681 gacctctggg acgagggcta cctggggctg gtgtcctcgg cctgaggccc cggcctgagg
    16741 ccccggcctg aggctccggt cggtggggct gatcggtgcg gctgaccggt ggggcacggc
    16801 gtcagacggg cttgcgggcc tcgatgagga agcgcgccga gtgggcgatg aaaggacctt
    16861 ccgccgtgat gcgttcgtgc agttcgcgca gccggtcgcg gtaccggccg acggtgaagc
    16921 cgggaaccat ccagatcacc ttccgcagga agtagatcac cgcgccgacg tcgaagaact
    16981 ccatccgcag ggactcggcg cgcaggtcga cgacgccgag ccccgccgcc tccgcctccc
    17041 gtcgctcgtc gtcggggtgc cgcttgcgcc gtacctcctc cggctgcggg cccaggaagt
    17101 actccaccag ctcgaaggcg ctggccgggc ccacgtgctg cgcgaggtac gtgccgcccg
    17161 gccgcagcac gcgggcgatc tcctcccacc acaccgtcgc ggggtgacgg ctggtcacga
    17221 ggtcgaacgc ctcgtcggcg aagggcagcg gaggctcgtc ggcatcggcg accacgaccg
    17281 ctccgagggg gtgcagcagc ttcgtcgcct tggcgacatt gggcggccag gactccgtgg
    17341 ccaccatcgt gcggggcagc ttccgcgcgc cggcgaggac ctccccgccg cccgtctgga
    17401 tgtcgagggc cgcgtctgcg cgggccaggc gttcgctcat ggtgcgctga tagccccagg
    17461 agggacgttc ctcggtggcc cggccctcca gccaggagaa gtcccagccg gccacggggg
    17521 cggcctcggc ctcggccacc aggtcgtcaa agcttcgtga cgtatcactt cgtgacatat
    17581 cagaagtaat accgcaacag ggactcggag gctcggggga gggaggcggg ggaggggtgc
    17641 caggggatgg ggctcaaggg ctcggtggcg gccttcacca ccggagggac tcattcccgg
    17701 tggggcgcgg catgggaacg ggcataccgc gaacagacgt gcgtgtcgcc gtgcggtgcg
    17761 gcgcgtaccc caccccccag ccccgaggag tcgtgatggc ctggtacccg ggcgccacga
    17821 agatggagct ccagccggag tcggacgacc agccggcgat ccggcccacc cagttcatcc
    17881 tgcacagcgt cggcgcgccg tggacctcgc gccgcatcta tgcattctgg cacgaaagca
    17941 ccaatctcga gtcgcatttc ggcctcggtt acggaggcga cctcgcgcag tacatcggca
    18001 cccagacccg cgccgacgcc aactaccggg ccaacctgcg cccggacggc agcggggcgg
    18061 tgagtatcga gaccgcctcc aacctggaac acaccgaccc gtggaccgac cggcaggtcg
    18121 acagactcgt cgaggtcgga gtgtggctgc accagtacca cggcctgccg ttacgggtct
    18181 gccgctcctg ggacgaaccc ggctacggat accaccggct gttcccgcag tggtccacgg
    18241 gcggcacggc ctgtccgggc gacgcgcgcg tggggcagtt ccacgacgcg gtcttccccg
    18301 ccatcgtggc ccgggcctcc ggcaggcccg ccgatccgcc gcagccgggc ggggctccgc
    18361 ggacgctcgg cgagtacagc gacgcgcaga ccgccctcgt ccccggcgcg tggacgaccc
    18421 tctcggtggg cggcgaggcc ttgatcagcg gcgcgaaggc gtacacggcg acggtcttcc
    18481 tgaccgtgac cgtcccggcg ggcagtacgc tccagggccg cttctatcac cagcgggcgg
    18541 acggctcccg ctggaacggc ccgatcgtcg agcgcatcgc gacggtgggc gcgtccttcg
    18601 tggacttcac ccaccagggg tccgtctccg aaggggagac cgtccgcttc gaggcgtgct
    18661 acgacccgcc ggcaccgggc gtacgcgacc cgggcacggt ggcgacgtcg cgggcgcgcg
    18721 ggttgtactg gacctgacct gacctgacct gacctgacct gacccgacct ggcacaggag
    18781 atccggccgg gtcaggcctg cggcgctccc ggcccggccg gctccgcgat cagcgccgtg
    18841 cccgcgcggc ggaagccggc ccgggcgtag atccgggcca cgtcgtcgtc gccggcggac
    18901 aggaagacgg tctccgcgcc ccgtgcccgc gcatcggcga ccagggccgc ggtgaccgcg
    18961 aggcccagac cctgccggcg cacggcgggc agcgtcccga tgccgaccag ctcggtgacc
    19021 gcgccgaccg gctggtgcat gcccgaacac agggccgtgt cgccgcggac ggccgcggcg
    19081 agcaccgtca ggcccgcacg gatgcgtgcc gccagacggt ccgccgtgcc gtcccgcgcg
    19141 gcgagccgct ccgccgcctc cagttcctcg gtgcccgtgg gccccaccgc ggtgccgggc
    19201 tgggagaagg cgagcgggcc gagggccacc gcgctcggca gggcggggtc gtccggggcg
    19261 agcagccgga cggcaaggcc ctcgggcagc acgggatcgg ccggggcggt gcccggttcg
    19321 agcaccatca gggggtgctc gtgcaccgtc agccccgcct cctcggcggc cgcccgcagc
    19381 gcgggcgtcg tctcggccac ccactcgaag ctctccggaa ggccgagttc gcgctggcgg
    19441 gcccggaccc ggagcaggtc ggcagcgctc accggtccgg agccggccgg gccccgggag
    19501 gggcgggcgt agtacggcca gccctcgccc tcgcggacga agagggtgag cgggccgaag
    19561 tcctcggccc gggcggtgct gcgcggcacg ctgtcgtaat agccctccag gcggtcgagc
    19621 agcccggggc cgggggaatc ggaggtgtgc gcggaagggc ggacggaagg gccggcggaa
    19681 ggggcggcgg aagagtcggc aggcatcacg acaggcatcc aacacgcgcc gtacgccccg
    19741 ccgccacccc atttcaccgc accccgatca cgtacaccct gtagtcgatg gttaacgccc
    19801 cgctatcctg ggcccggtgt cgaggagacc agatcatgtc accggggccg caagcgcccg
    19861 cctgtcgcgc cgccgtctgc tgggctgggc cgccttcggc gccgcttccc ttacgggggc
    19921 gaccacgatc acggctgcgg ccgggccccg ggtgtccgcc gccgccgacc cggtcggcag
    19981 cggtgcgttc gtaccggccg tggtggtcgg caccggctac ggggccgcgg tcaccgccct
    20041 gcggctgggg gaggccggcg tcggcacgct gatgctggag atggggcagc tgtggaaccg
    20101 tcccgggccg gacggcaagg tcttctgcgg gatgcccgac cccgaccgcc gctccacctg
    20161 gttcaagaac cgcaccgagg cgcccatcgc ctccttcctc tggctcgacg tcgtcaaccg
    20221 caccatcgag ccttacgcgg gcgtgctcga ccgcgtgaac ttcggtcaga tgggggtgta
    20281 cgtggggcgc ggggtgggcg gcggctcgct cgtcaacggc ggtatcgccg cgacgcccag
    20341 gcgctcctac ttcgaggagg tgcttccgca ggtcgacgcc ggcgagatgt acggccgtca
    20401 cttcccgcgc gccctcgcga tgctcagggc gaacgaggtc gccgcggact ggttcgagca
    20461 gacggagtgg taccgcttcg cccgcgtcgc gcgcgaggcg gccgcgaagg cggggatgag
    20521 gacgaggttc gtccccaacg tctacgactt cgcctacatg cggcgcgagg cggcgggcga
    20581 ggtggcgaag tccgcgctgg ccgccgaggt catgtacggc aacaaccacg gcaagcagag
    20641 cctggacaag acctatctcg ccgccgccct cggcaccggc aaggtcaccg tcgagaccct
    20701 gcaccgcgtc acggcggtcc gccgcgagga ggacggcacg tacgtcctga gcgtggaccg
    20761 gatcgatgcg gaggggcggc ggctcgcgcg caaggagatc ggctgccggt acctcttcct
    20821 cggcgccgga agcctcggct ccacggagct gctggtccgg gcccgcgaca ccggcaccct
    20881 gccggacctc ggtgcggagg tcggcgcggg ctgggggccg aacggca
//
