LOCUS       NZ_BMUT01000007        21335 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces hiroshimensis strain JCM 4586 sequence07, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUT01000007
VERSION     NZ_BMUT01000007.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces hiroshimensis
  ORGANISM  Streptomyces hiroshimensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 412151)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 90X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650335.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:32:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,830
            CDSs (total)                      :: 6,745
            Genes (coding)                    :: 6,620
            CDSs (with protein)               :: 6,620
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 25 of 125
            Pseudo Genes (incomplete)         :: 107 of 125
            Pseudo Genes (internal stop)      :: 4 of 125
            Pseudo Genes (multiple problems)  :: 11 of 125
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 245476
            Orig. end                         :: 266811
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUT01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21335
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="triceptide"
                     /region_number="4"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..21335
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21335
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11335](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11335)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     gene            455..955
                     /locus_tag="IE241_RS18060"
                     /old_locus_tag="GCM10010324_37000"
     CDS             455..955
                     /EC_number="2.1.1.63"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013222.5"
                     /locus_tag="IE241_RS18060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37000"
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="WP_190022789.1"
                     /transl_table=11
                     /translation="MRSSTLPTPLGPFSLLTVEDGILAAGFTPDPSALLPELPAPWRGR
                     EPVPTEVPEPYASALAAYFAGRVEAIDALSVVQSGSGFRMAAWREMRRVRPGTTVSYQE
                     LAASAGRPGAARAAGAACADNLVPLIVPCHRIRRSDGTLGGYYYGLAVKRWLLDHEKGA
                     GSR"
     gene            952..2193
                     /locus_tag="IE241_RS18065"
                     /old_locus_tag="GCM10010324_37010"
     CDS             952..2193
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639820.1"
                     /locus_tag="IE241_RS18065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37010"
                     /product="MFS transporter"
                     /protein_id="WP_190022790.1"
                     /transl_table=11
                     /translation="MNAYWRVLRSGDFGRLWLGASVSLLGDGMTFLALAWLVLDEGGTG
                     RLGLLGVCFTAPVVVGGLLVGPLLDRFDKRTLLIADSVFRAACVASVPLAAAVGGVPVW
                     LPFLVAVVYGLLKMVPLAGFPAAIPQLVGDRDLDTANALESLSFSVATVVGPAVAGVLV
                     GAVGAPQVLLVDAASYLVFAALVATVRRPLSPPPRAGRQAPKASLKAVARDRVIVSTTV
                     AFMLFNIADGMLILVVGPWLAKNELHGGASVLGALTAAAAAGEFLGAAVAGGGRLGPAS
                     VRLIGLFQTGAALAFLAVLGSPLEAVVGAGFFAVGLLSAPMTVWAQSLRMRRIAPELHG
                     RAFAGLRTLMTGTAPLGAVIAAPLLAGGSLAAAAVTMACCAGLPGLYLLLSSGGTGSAP
                     AAAPEAVPERADTG"
     gene            complement(2109..3539)
                     /locus_tag="IE241_RS18070"
                     /old_locus_tag="GCM10010324_37020"
     CDS             complement(2109..3539)
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014803.5"
                     /locus_tag="IE241_RS18070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37020"
                     /product="alanine racemase"
                     /protein_id="WP_190022791.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.2e-33, bitscore:
                     110.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.8e-15,
                     bitscore: 51.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAPQPAPQPVPQPVPQPVPQSAPAVPWPAQQWSPGTGVRPALPP
                     SALPRPVVERLRRLAQEAGPEPLCAYVHDPAAAARRAALLRARLPDWAEVFYAVKANSF
                     PATLEALAPGTDGFDVSSEGEAGAARAASARALIATGPGKTDAMLTAAVRAGADFVSAE
                     STLELHRIAAAAHRAGRRVPVVLRVNAATGPLQGALCMDGHATQFGIGEDDLPEAAAVA
                     RSLPGLDLVGYHFHVVSNNLDADAHADHLRARLHWAVRAAREHGFALRVLDAGGGLGVA
                     PRGVAPFDLGRFAARLRAAPPPPGVRVVLEPGRWLVADSGYYAAQVTDVKEVAGSRFAV
                     LAGGINHFMLPALLEVALDAAVVDVGRWPYACPRPTLRDTTVSLAGPLCTPEDILARGI
                     HVGRLRAGDLVVFPLAGAYGWEFALRGFLGRRPPVHTVVSTAVSTAVSTPQPVSARSGT
                     ASGAAAGAEPVPPEDSSR"
     gene            complement(3539..4606)
                     /locus_tag="IE241_RS18075"
                     /old_locus_tag="GCM10010324_37030"
     CDS             complement(3539..4606)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) pgm_amidino"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995680.1"
                     /locus_tag="IE241_RS18075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37030"
                     /product="amidinotransferase"
                     /protein_id="WP_190022792.1"
                     /sec_met_domain="pgm_amidino (E-value: 8.3e-94, bitscore:
                     308.6, seeds: 95, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVVSSHNEWDPLEEVVVGRVDGAMTSSWEVLDRISVPPAAQEHL
                     GASAGTRMPQDAVEEAERGLEELIGILHDAHVTVRRPDPPDTSRPFATPAWAVANGISA
                     ANPRDLLLVVGDEIIEVPMADRNRYFETWPYRGLLAEYFERGARWTAAPKPRLLDAQYR
                     PGYEIPPPGEEMTYLVTEAEPVFDAADVMRCGRDLFMERSHVTNALGLEWLRRHLGPEY
                     RVHEVVSRYPRAMHIDTSLLPLAPGKVLVNPEFIDPEGLPSAFRSWDVLIPPEPVVTPV
                     MQRGLMSVWSSLNVLMLDPAHVVVERSQTPLIKAFEQWGFDPVPCSFEHYTAFGGAFHC
                     ATLDIRRTGPLETYF"
     gene            complement(4653..5681)
                     /locus_tag="IE241_RS18080"
                     /old_locus_tag="GCM10010324_37040"
     CDS             complement(4653..5681)
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065837.1"
                     /locus_tag="IE241_RS18080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37040"
                     /product="fatty acid desaturase"
                     /protein_id="WP_190022793.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 2.8e-16,
                     bitscore: 53.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTAPREGEQLGLDGSLDGSHDVALAPVRGTDTRRGLPASYFER
                     RPRRFIAKIAVAFAVIVVCWTALLEFRNPVTCVAAVLVLGVMYAYLVELQHECLHEHAF
                     HARWANRTWGFVCGVFMFSSYSHYKYEHLRHHAFLGTPRNQEFFNYRFHGLDSVHGFAL
                     AAFHPGRYADVLRNLGRGAARRPIPGVERPRAARAIQSEYALLLVLLAGAVAAGVLTRD
                     WFVVLAWFAPALLVSEAAHFLIEMPEHFGLNTQTDDNVLGNTRTIHASTFARWLTNYNN
                     LHTAHHYHQGVPMVNVPQLHAAMQEKILVTETSYWSFYRKVLKGEIAYQGGRASDENCM
                     TR"
     gene            complement(5724..6722)
                     /locus_tag="IE241_RS18085"
                     /old_locus_tag="GCM10010324_37050"
     CDS             complement(5724..6722)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS18085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_37050"
                     /product="hypothetical protein"
                     /protein_id="WP_190022794.1"
                     /transl_table=11
                     /translation="MTPAVTVTRSHDIARLDAGTGETRTRLAMTAASGESGTWRLSATT
                     APPGTGEEPDPGRHALAVHRALRGRAAPALGEDGLLVEAGRITTDVTCDGRRVAVSART
                     YLLVRDRDRVLHLQDGTDPPRSLPWAAAAGPGDVRPGDPVVLGPAALLALTAAAHEEDG
                     TAGAPGSGCSSPYPPHDFPLHGLVTATGRPHADLCRACELLAEPDRWLVPHGTFGTGTR
                     PPAVADRPPRKAFPPRALLLDSLTPCGRCADGRPDWLAAYCLVDGAEQARGRGLLRVRG
                     APDALLREAGAACAPARPALARDPIGRESYAQAPCVTTALTAGRLIVPAHP"
     gene            complement(6719..7966)
                     /locus_tag="IE241_RS18090"
                     /old_locus_tag="GCM10010324_37060"
     CDS             complement(6719..7966)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039907.4"
                     /locus_tag="IE241_RS18090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37060"
                     /product="metallopeptidase TldD-related protein"
                     /protein_id="WP_190022795.1"
                     /transl_table=11
                     /translation="MPADARAIRADAPAIPAEAPAGETVACERAVGGLVTAGPRGTSAH
                     RLSTRMGRHDRGPGRGTRIFSGDPPAPWRTGLPEPEPPDDHDEVLAALTALRDRFGGRA
                     DLQFSQVSSVRVVAGTAHGTTAPQARRVWSLTGGLLTPGGHEVPVGRSGRGPALPRLTD
                     PAWCESAARLLAAVDAARAAEPGECAAVLMPQAAGVLLHEAAGHFAEASPGGTPALAHR
                     LGCRVAGELITLDDDPLAEGGPAHYDTDDEGIVCLGRQRIVHEGRLVRQLHSLSSAAAE
                     AAMPTANSRAASVLHRPVPRMSNVVCRPGDAETGALVENAGHGLLVHRLADGIRTGATL
                     EARLVLGELIRSGRRTGEYVRGRLRERADVLTRVVETGAHAEFGDNALCGKDGQLLFDV
                     GMCAPALRLSRLRCTP"
     gene            complement(7956..10004)
                     /locus_tag="IE241_RS18095"
                     /old_locus_tag="GCM10010324_37070"
     CDS             complement(7956..10004)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="IE241_RS18095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37070"
                     /product="radical SAM protein"
                     /protein_id="WP_190022796.1"
                     /sec_met_domain="PF04055 (E-value: 4.2e-25, bitscore: 83.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKVALATSPHLNHGGMSLRTRPGDPPPMQNFVPVGLLSLKAAAD
                     AAGAPAAIEVVETNQLLLDGAVPNDDALYDGLARSVLAAGDSLVGLMTDADSLVHTVLL
                     GQALRRRSPDTRICLGGPAVTPISAEFLDRFPWADFIVRGEGEATFTELLETLHAGQDP
                     SGVRGLTHRKDGRAVVNAERPLFQDLAELPWPAYYAYDMSKGARLYLDVGRGCPFRCSF
                     CATAPFWERKFRMRPIDDIIRQLEYVRDAFGRTSVNFSHDIFTCDRPWAHKFCDAVIAR
                     DLGVTWGCSTRTDLIDAELLDKMGAAGCEEIYYGIESGSPKMQRWIKKNLDLERSLEVV
                     RATKAAGIRPVTGFIVGYPTETRETMSETLTRFFQFLEEGQGRSQLFTLVPLHQSPMYK
                     QYAPTLNRPAEYYDIPVTDRPMAQIQQYRREHKDMFCTDYRFACPEVGDALIDAAEELS
                     GHVVVLASLWPRLLPYYDSPMDWYERWVAWIEEYNAEHAPGTRFRHQSEARDLLVFAQE
                     ETVRLGIEDSPAASLVRYEMMRLAAADLPEPPPRPAAPSVGPESALRAGDFLSAEFPHD
                     LHRMLRGPAEEPAAEDGKGSANGSSYVVTRKSASDKIETIQLGRSARDLLERADGRRTA
                     RQLIAEVFPEEAGDPDTTLRRGLELVRSLAGMGLLLEAPVNGDTDAR"
     gene            complement(10001..11335)
                     /locus_tag="IE241_RS18100"
                     /old_locus_tag="GCM10010324_37080"
     CDS             complement(10001..11335)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="IE241_RS18100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37080"
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_190022797.1"
                     /sec_met_domain="PTHR43273 (E-value: 9.2e-40, bitscore:
                     131.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.6e-19, bitscore: 65.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.4e-09, bitscore: 30.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.8e-07, bitscore: 25.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.1e-08, bitscore:
                     27.4, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.7e-07, bitscore: 25.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQHVSSCTPEYARRLPPRTRPLIRYRREDFGWLAAFPDGSVAMY
                     DEGAEALLRAGEPPERCTDHLVERLSVETDFHFRAPAMVWLEITRSCNLRCPHCFVEGG
                     RARSSELPTELIMRLLDEWAAMGVFSLIVTGGEPTMHPDFCDIVQRAYDLGFVIGIATN
                     GTTLGERILSRIPQDDVIISMSIDGLHGQGKYRNEGEFAYVTRRLAELRDRGFNTSIMT
                     TTTHENVDDLPVIIGWAKENDVSLRSVPFIPMGRGALHHDLASSMHDVERTARFWIDEE
                     EWGREKDRTLGLCAGKVLDFLYTMVFATRRCMSGRGVCYVNSAGDVFPCSTCAGNKVLC
                     GGNVQLTPFAGIWESEDWLVRKITWDNYRDTCEGCPINDDKYFCTGRCPSQSSILNGTF
                     DGCGTSDFQRQSILRREELFRERIMAEPRVELRRGEHSTVPGERS"
     gene            complement(11483..11980)
                     /locus_tag="IE241_RS18105"
                     /old_locus_tag="GCM10010324_37090"
     CDS             complement(11483..11980)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024865.5"
                     /locus_tag="IE241_RS18105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37090"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_190022798.1"
                     /transl_table=11
                     /translation="MTIDFVPTVTAGAITREAVQQLLEEYRSAYDRCDQGYFDLFAPDA
                     TFFILSSPTRIDSREEFQRVFTLSAGPARRSQLLSPEIRILGDTALVSLHCRVALGEEQ
                     QYLRETLVVTRGARGELRIAHLHISPQDMPSVPDSPERAVEEISVIEERTATTASTVGT
                     PK"
     misc_feature    complement(11966..11981)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.88"
                     /tool="antismash"
     misc_feature    12140..12155
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    complement(12267..12281)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.33"
                     /tool="antismash"
     gene            12456..13004
                     /locus_tag="IE241_RS18110"
                     /old_locus_tag="GCM10010324_37100"
     CDS             12456..13004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556798.1"
                     /locus_tag="IE241_RS18110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37100"
                     /product="hypothetical protein"
                     /protein_id="WP_190022799.1"
                     /transl_table=11
                     /translation="MELMRYVDNLRQELLVAAEAGDAESREVAERLVAPLSSAVRLVLL
                     DALSAAADEITSDLAPGSVEVRLRGLDPSFVVTLPPADHGPGDAEGGFERPHAGAVPSL
                     PAAPPAPAGGEDGATSRINFRPPEHLKARIEEAAGREGLSVNAWLVRAVSAMLDFDEQA
                     RRPERRAPRGGQHYTGWVT"
     gene            13057..13902
                     /locus_tag="IE241_RS18115"
                     /old_locus_tag="GCM10010324_37110"
     CDS             13057..13902
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641565.1"
                     /locus_tag="IE241_RS18115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37110"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_190022800.1"
                     /transl_table=11
                     /translation="MPVFETPHPITVSVDLPVGDVRLRAGDRTDTVVEVRPSDPGSAAD
                     TKAAEDTRVEYAGGRLLVKGPKPRVFGRAGSVDVTIGLPSDSEVQGTGQMTAFHCSGRL
                     GECRIKTSTGGIHLQESGRLTATTSLGDVTADRVDGTAAITTGTGGVRAGALTGPAVIK
                     NSNGETWVGEASADLRVRSASGSIAVGTAHADLEAKTAHGDIRVGEVVRGSAVLATSSG
                     QIEIGIRPGTAARLDVRTKFGHVHNLLTASDGPGRSDERAEVYATTSVGDVTVRRAGGA
                     "
     gene            complement(13966..14955)
                     /locus_tag="IE241_RS18120"
                     /old_locus_tag="GCM10010324_37120"
     CDS             complement(13966..14955)
                     /NRPS_PKS="Domain: PKS_ER (15-273). E-value: 2.3e-11.
                     Score: 35.3. Matches aSDomain:
                     nrpspksdomains_IE241_RS18120_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955874.1"
                     /locus_tag="IE241_RS18120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37120"
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_190022801.1"
                     /sec_met_domain="ADH_N (E-value: 3.7e-35, bitscore: 114.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-17, bitscore:
                     58.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAVVEAPGRIRIATLADPAPGPHEVVIDVAACGLCGTDLHIVQ
                     GGCAASLPVVPGHEFAGEVVGTGSGVTRLRVGDRVAVDPSLYCQECRYCRMGRGNLCDR
                     RGAIGVTAAGGAAEYALAPAANCVRLPEHVDVRDAPLIEPLSCAVRGYDVLGSRLGADV
                     LIYGSGTMGLMMLELAKRTGAGSVDVVDVNPARLATARALGCTRTAASAQELEQARGWD
                     VVIDATGNAAAIQDGLGRVAKAGTFLQFGVSELAATATIEPYRIYHHEITITGSMAVLH
                     SYERAAELFAAGVLDPGVFISHRLPLERYPEAMDRFRAGEGCKIVVVP"
     aSDomain        complement(14137..14910)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE241_RS18120_PKS_ER.1"
                     /evalue="2.30E-11"
                     /label="IE241_RS18120_PKS_ER.1"
                     /locus_tag="IE241_RS18120"
                     /protein_end="273"
                     /protein_start="15"
                     /score="35.3"
                     /tool="antismash"
                     /translation="TLADPAPGPHEVVIDVAACGLCGTDLHIVQGGCAASLPVVPGHEF
                     AGEVVGTGSGVTRLRVGDRVAVDPSLYCQECRYCRMGRGNLCDRRGAIGVTAAGGAAEY
                     ALAPAANCVRLPEHVDVRDAPLIEPLSCAVRGYDVLGSRLGADVLIYGSGTMGLMMLEL
                     AKRTGAGSVDVVDVNPARLATARALGCTRTAASAQELEQARGWDVVIDATGNAAAIQDG
                     LGRVAKAGTFLQFGVSELAATATIEPYRIYHHEITI"
     gene            complement(14952..15824)
                     /locus_tag="IE241_RS18125"
                     /old_locus_tag="GCM10010324_37130"
     CDS             complement(14952..15824)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359189.1"
                     /locus_tag="IE241_RS18125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37130"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_190022802.1"
                     /transl_table=11
                     /translation="MTAADADAAALPPEARRARCRGLLPGLLAWLAGLVLFLPVAWMVL
                     TSLHSESDAATNPPSVAASLTLDGYRTFFGAGGGTSPWPALINSATAGVTSTVLVLTLA
                     LPAAYALSIRPVRKWTDALFFFLSTKMLPVVAGLLPVYLFARDTSLLDNIWLLVVLHTS
                     MNLPVAVWMLQSFLSDIPVSLVEAARLDGARLPAVLGRVVAPLAGPGIAATALICFIFS
                     WNELLFARALTAVTAQTAPVFLTGFITSQGLFLAQVCAASVVISLPVLAGGFAAQDKLV
                     QGLSLGAVK"
     gene            complement(15821..16795)
                     /locus_tag="IE241_RS18130"
                     /old_locus_tag="GCM10010324_37140"
     CDS             complement(15821..16795)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141210.1"
                     /locus_tag="IE241_RS18130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37140"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_190022803.1"
                     /transl_table=11
                     /translation="MTDPLTAAPAARAGAVPRTAGPRPKPPALRAWATRAPLLPALVFL
                     IAVTQLPFAATLVISLFDWNALRPGERRFTGLSNYTAVVHDAGLRDAVVTTMVLTASVV
                     VTSLVLGLLLALLLDRSFRGRGLVRTLLIAPFLLVPVAAALLWKHVLYNPEYGLLNGAL
                     TWAGRLFGVDSPPQPDWISSMPLPAVEAALVWQWTPFMMLILLAGLQSRSPETVQAARL
                     DGAGDWQVFRYVTLPHLRRYLELGTLLGAIHIVQNFDAVFTVTSGSLGTANLPYAIYRT
                     FYQAHEYGQASAAGVLVVTGSAVIATFALRVVSSLFRGGVSRG"
     gene            complement(16792..18150)
                     /locus_tag="IE241_RS18135"
                     /old_locus_tag="GCM10010324_37150"
     CDS             complement(16792..18150)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007828613.1"
                     /locus_tag="IE241_RS18135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37150"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_190022804.1"
                     /transl_table=11
                     /translation="MTHRTPRGPRALVAAAAASGLLAACAGAGGTAAFGGDALNVLMVN
                     NPQMAQLQKLTAAHFTKATGIKVNYTLLPENDVRDKTGQDFSHQTGQYDVATISNYEVP
                     FYAKNRWLLPLDAYAAQDTAFDQDDILKPVRDSLTADDGRLYAEPFYGESSFLMYRKDV
                     FAEKGLTMPARPTWEQVAGLAAKADGARPGMKGICLRGQPGWGEVIAPLTTVVNTFGGT
                     WFGEDWRAQLTAPEFVRATEFYVGLVRKHGEAGAAQAGYAECLNSLTQGRTAMWYDATA
                     AAGSLEAAGSPVKGRIGYAPAPVDRTKSSGWLYTWAWGVQKAARHPDKAWKFISWASGK
                     AYEALVGKEAGWAAAPAGKRASTYANEDYRKAAGAFAEVTREAIGSADPRSPGTQPRPA
                     PGIQFVGILEFSDLGTRVSQEISAAIAGRRSVGEALRKSQAMAAKIGEEYRNR"
     gene            complement(18220..18981)
                     /locus_tag="IE241_RS18140"
                     /old_locus_tag="GCM10010324_37160"
     CDS             complement(18220..18981)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712763.1"
                     /locus_tag="IE241_RS18140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37160"
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="WP_229899445.1"
                     /transl_table=11
                     /translation="MEAEERRRGMLELARRNGMVDVGKLAVDFGVSRETVRRDLRVLEE
                     HGLVRRTHGGAYPVESAGYETTLAFRTTMHVLEKQRIAAAAGEVVGDAETVFVDEGFTP
                     QLIAQALPRDRPLTVVTASLAAASSLASAELVTVLLLGGRVRGSTLATVSHWATRMLAG
                     FVIDLAFIGANGISREYGLTTPDPAVGEVKAQAVRVSRRRVFAGVHTKFGAGSFCRFAD
                     VSDFETIITDTALPLAEAHRYSLMGPQVIRV"
     misc_feature    19353..19369
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.79"
                     /tool="antismash"
     misc_feature    19515..19530
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.2"
                     /tool="antismash"
     gene            19609..20154
                     /locus_tag="IE241_RS18145"
                     /old_locus_tag="GCM10010324_37170"
     CDS             19609..20154
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175414.1"
                     /locus_tag="IE241_RS18145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37170"
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="WP_190022805.1"
                     /transl_table=11
                     /translation="MKIVRNRPGPLTGLDVFVGGPIQHAILPGGFTASLQDAISTAIAV
                     VEENGGNIFSAHVVEKFGAETDSFTPEQVSVRDYRWMRKCDVFVPVLPLLDDKTLHRTD
                     GTHVELGWATAMGRPVVLITRQPFAESASHLLKGLHRVGSVHAVDFDEFAGKPDLLIDA
                     IVSATGQQQKAVQAGIPA"
     gene            20173..21036
                     /locus_tag="IE241_RS18150"
                     /old_locus_tag="GCM10010324_37180"
     CDS             20173..21036
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515025.1"
                     /locus_tag="IE241_RS18150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_37180"
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="WP_229899446.1"
                     /transl_table=11
                     /translation="MSAVHVLGLRIRNAVIVGSGLLTDQERNIRRLLETGAGAVVTKTI
                     HPSPPRGLDERLVRLPVGMLNSTTYSKRTVDHWLMVLRSFAQDDLPVIASLHADTPREL
                     GALAAEVQATGCRALELGISCLNEGPGLTDDTPERVYAYAAATRSRTSLPFSVKLAIGE
                     GLEARVRAALAGGADAVTVSDTIPGAAVVPDTGELELGGTFGYSGPGIKPLVLAAVWRL
                     RKRGFDLPVLGCGGVASGRDVADYLSVGAQAVQVYTALHTDTYATLDRIVGEAAGLAQG
                     PLEAAT"
ORIGIN
        1 ccgtacgggc cctggccggt gcggtggccg ccgagaagct gtccctcgaa cgggacgccg
       61 accgggagga gacagcggcg cggctgcgcg agctgcccgg tgtgagcgaa tgggccgtgc
      121 agcgcatcgc gatgcacgcc ctgggcgacc ccgacgcgtt cgccccgcag gacccgcagg
      181 tccgggccgc ggcgaaggcg ctcggcctgg ccgggggccg cggagccggc cggctggcgg
      241 aacacgcccg ggcctggcag ccctggcgct cgtacgcggc actgcacctg cgggaggcgg
      301 cgccccctcg gtaacgcgcc cgataagggg cgcggggcgg tgttacatct gcggctccgc
      361 cgcgtgggcg cgaccggcca ccaacggccc gcagccgacc gactgtccac cgggcggagc
      421 ccggagcctg aggagaacga tgacagcgca aggcatgcgc agctcaactc tgcccacacc
      481 cctcggcccc ttcagcctgc tgaccgtcga ggacggaatc ctcgcagcgg ggttcacgcc
      541 ggacccgtcc gctctcctgc ccgagctccc cgctccgtgg cgcggccgcg agccggtgcc
      601 gacggaggtc cccgagccgt acgcgtccgc gctcgccgcc tacttcgcgg gccgggtcga
      661 ggcgatcgac gcgctgtccg tcgtgcagag cggcagcgga ttccggatgg cggcgtggcg
      721 ggagatgcgc cgggtccggc ccggtacgac ggtcagctac caggagctgg cagcgtccgc
      781 ggggaggccg ggcgcggcgc gggccgcggg cgccgcgtgt gcggacaacc tggtgccgct
      841 gatcgtcccc tgccaccgca tccgccgttc ggacggcacg ctcgggggct actactacgg
      901 cctcgcggtc aagcggtggc tgctcgatca cgagaagggt gcgggcagcc ggtgaacgcg
      961 tactggcggg tgctgaggtc gggggacttc gggcggctgt ggctgggcgc gtccgtgtcg
     1021 ctgctcggtg acgggatgac gttcctggcc ctggcgtggc tggtgctcga cgagggcggc
     1081 accggccggc tggggctgct gggggtctgc ttcacggccc cggtcgtcgt gggcggcctg
     1141 ctcgtggggc cgctgctcga ccggttcgac aagcggacgc tgctgatcgc ggacagtgtg
     1201 ttccgggccg cgtgcgtggc gtcggtcccc ctcgcggcgg ccgtcggcgg ggtgccggtg
     1261 tggctgccgt tcctggtggc ggtggtctac ggcctgctca agatggtgcc gctcgccggg
     1321 ttccccgccg cgatcccgca gctggtcggg gaccgcgacc tcgacaccgc gaacgccctc
     1381 gaatcgctga gtttcagcgt ggcgaccgtc gtcggcccgg ccgtggccgg cgtgctggtc
     1441 ggggcggtcg gcgctcccca ggtgctgctc gtcgacgcgg cgtcctacct ggtcttcgcg
     1501 gccctggtgg cgaccgtgcg ccggcccctg tcgcctcctc cgcgggcggg gcggcaggcg
     1561 ccgaaggcgt cgctgaaggc ggtcgcgcgc gaccgggtga tcgtctccac gacggtcgcc
     1621 ttcatgctct tcaacatcgc cgacgggatg ctgatcctgg tcgtcgggcc gtggctggcg
     1681 aagaacgaac tgcacggcgg ggcgtcggtc ctgggtgcgc tgaccgcggc cgcggcggcc
     1741 ggggagttcc tgggcgcggc ggtggccggc gggggccgcc tcgggcccgc ctcggtgcgc
     1801 ctgatcgggc tgttccagac gggggccgcg ctcgccttcc tcgccgtgct gggctcgccc
     1861 ctggaagcgg tggtcggggc gggcttcttc gcggtgggcc tgctgagcgc gcccatgacc
     1921 gtatgggcgc agtcgctgcg gatgcggcgc atcgcgccgg agctgcacgg gcgggccttc
     1981 gccgggctgc gcacgctgat gacgggaacg gcgccgctcg gggcggtgat cgccgccccg
     2041 ctgctggcgg gcggcagcct cgccgccgcg gccgtgacga tggcctgctg tgccgggctg
     2101 ccgggcctct acctgctgct gtcctccggg ggcaccggct ccgcgcccgc cgccgccccc
     2161 gaggcggttc cggagcgggc cgacaccggc tgaggtgtgc tcaccgctgt actcaccgcc
     2221 gtgctcacca ccgtgtgcac cggagggcgg cgcccgagga agccgcgcag ggcgaactcc
     2281 cagccgtagg cacccgccag cgggaagacc acgaggtccc cggcgcgcag ccggccgaca
     2341 tggatgccgc gggcgaggat gtcctcgggg gtgcacaggg gtccggccag ggagacggtg
     2401 gtgtcccgca gggtggggcg ggggcaggcg tacggccatc gcccgacgtc cacgacggcg
     2461 gcgtcgaggg cgacttccag cagtgcgggc agcatgaagt ggttgatgcc gcccgcgagg
     2521 acggcgaacc ggctgccggc cacctccttc acgtccgtca cctgggccgc gtagtagccg
     2581 ctgtccgcca cgagccagcg cccgggttcg aggaccaccc gtacgcccgg cgggggcggg
     2641 gcggcgcgca gccgggcggc gaacctgccg aggtcgaagg gtgccacgcc gcgcggcgcg
     2701 acgccgaggc cgccgcccgc gtcgagcacg cgcagggcga agccgtgctc gcgggcggcc
     2761 cggacggccc agtgcagccg cgcgcgtagg tgatcggcgt gggcgtcggc gtcgaggttg
     2821 ttggagacca cgtggaagtg gtagccgacg aggtcgaggc cgggcaagga gcgggcgacg
     2881 gcggccgcct ccggcaggtc gtcctcgccg atgccgaact gcgtggcgtg gccgtccatg
     2941 cacagcgcgc cctgcagcgg gcccgtggcc gcgttgacgc ggagcacgac cgggacgcgg
     3001 cggccggccc ggtgcgcggc ggcggcgatc cggtggagtt cgagggtgct ctcggcgctg
     3061 acgaagtccg cgcccgcccg gaccgcggcc gtcagcatgg cgtcggtctt gccgggcccg
     3121 gtggcgatca gggcccgggc ggaggctgcg cgggcggcac cggcctcacc ctcggaggag
     3181 acgtcgaatc cgtcggtccc gggggcgagc gcttcgagcg tggccgggaa ggagttggcc
     3241 ttcacggcgt agaagacctc cgcccagtcc gggagccggg cgcgcagcag cgccgccctg
     3301 cgggccgccg ctgccgggtc gtggacgtag gcgcacagcg gctccggccc ggcctcctgc
     3361 gcgagccggc gcagccgctc gacgaccggg cgaggcaggg ccgagggcgg cagggccggg
     3421 cggacgccgg tgccgggcga ccactgctgg gcgggccagg ggaccgccgg ggcggactgc
     3481 gggacgggct gagggacagg ctgagggacg ggctgcgggg cgggctgcgg ggcggccatc
     3541 agaagtacgt ctccaggggg ccggtgcgcc ggatgtccag cgtggcgcag tggaaggcgc
     3601 cgccgaaggc cgtgtagtgc tcgaacgagc aggggacggg gtcgaacccc cactgctcga
     3661 aggccttgat gagcggtgtc tgggaccgtt cgacgaccac gtgggcgggg tcgagcatga
     3721 gcacgttcag gctgctccac acgctcatca gcccccgctg catcaccggg gtgacgaccg
     3781 gctccggggg gatgagcacg tcccaggacc ggaaggcgga gggaagccct tccggatcga
     3841 tgaactcggg gttgaccagg accttcccgg gtgccagggg cagcagggag gtgtcgatgt
     3901 gcatggcccg cgggtagcgg gagacgacct cgtggacgcg gtactccggt ccgaggtggc
     3961 ggcgcagcca ctccaggccg agggcgttgg tgacgtggct gcgctccatg aacaggtccc
     4021 gtccgcagcg catgacgtcg gccgcgtcga agaccggttc ggcctcggtg accaggtacg
     4081 tcatctcctc gccgggcggc gggatctcgt agccggggcg gtactgcgcg tcgaggaggc
     4141 ggggcttggg cgcggcggtc cagcgggcgc cgcgctcgaa gtactcggcg agcaggccgc
     4201 ggtagggcca ggtctcgaag taccggttgc ggtcggccat cggcacttcg atgatctcgt
     4261 ccccgacgac gagcaggagg tcgcgcgggt tcgcggcgga gatgccgttg gcgacggccc
     4321 aggcgggggt cgcgaacggg cgggaggtgt cgggagggtc ggggcggcgc acggtgacgt
     4381 gggcgtcgtg gaggatcccg atgagctcct ccaggccgcg ctccgcttcc tccaccgcgt
     4441 cctggggcat ccgggtgccg gcggaggcgc cgaggtgctc ctgcgccgcg ggcggtacgg
     4501 agatgcggtc gagcacctcc cacgacgacg tcatcgcgcc gtcgaccctg ccgacgacga
     4561 cttcctccag ggggtcccat tcgttgtgcg aggagaccac gggcatgagg gggcttcctt
     4621 ccgtgcgggg cggcgggacg acgaggacgg ggctagcggg tcatgcagtt ctcgtcgctc
     4681 gcccggccgc cctggtaggc gatctccccc ttgaggacct tgcggtagaa gctccagtac
     4741 gaggtctcgg tgacgaggat cttctcctgc atggcggcgt gcagctgcgg cacgttcacc
     4801 atggggacgc cctggtggta gtggtgcgcg gtgtgcaggt tgttgtagtt ggtgagccag
     4861 cgggcgaatg ttgaggcgtg gatggtcctg gtgttgccga ggacgttgtc gtcggtctgg
     4921 gtgttcaggc cgaagtgctc gggcatctcg atcaggaagt gggccgcctc gctcaccagg
     4981 agcgcggggg cgaaccaggc caggacgacg aaccagtcgc gggtcagcac accggccgcg
     5041 accgcaccgg ccagcaggac gagcagcagg gcgtactcac tctggatcgc ccgtgcggcg
     5101 cgcggccgct cgacgccggg gatggggcgc cgggcggctc cgcggccgag gttgcgcagg
     5161 acgtcggcgt agcggccggg gtggaacgcc gcgagggcga agccgtgcac gctgtccagg
     5221 ccgtggaagc ggtagttgaa gaactcctgg ttgcgggggg tgccgaggaa ggcgtggtgc
     5281 cggagatgct cgtacttgta gtgcgagtac gagctgaaca tgaacacccc gcagacgaag
     5341 ccccaggtcc ggttcgccca ccgggcgtgg aaggcgtgct cgtggaggca ctcgtgctgg
     5401 agctccacca ggtaggcgta catcacgccg aggacgagga cggcggccac gcaggtgacg
     5461 gggttgcgga attccagcag ggccgtccag cagaccacga tcacggcgaa ggcgacggcg
     5521 atcttggcga tgaagcggcg cgggcggcgt tcgaagtacg acgccggcag gccgcgccgg
     5581 gtgtcggtgc cgcggaccgg cgccagggcc acgtcgtggg agccgtcgag ggagccgtcg
     5641 aggccgagct gttccccttc gcggggagcc gtgcgggaca tggctgttcc tccttctgcc
     5701 ggggggtggg ggcgctccgc gggttacgga tgcgcaggga cgatcagccg gccggccgtc
     5761 agcgccgtgg tcacacaggg ggcctgtgcg taggactcgc ggccgatcgg gtcgcgggcg
     5821 agtgccgggc gggccggggc gcaggcggcc ccggcctccc gcaggagtgc gtcgggcgcg
     5881 ccccgcaccc gcaggagccc cctcccccgg gcctgctccg caccgtccac caggcagtac
     5941 gccgcgagcc agtcgggacg gccgtcggcg cagcggccgc agggcgtgag ggagtcgagg
     6001 aggagggcgc gcggggggaa ggccttgcgg ggtgggcggt ccgctacggc cggggggcgg
     6061 gtgccggtgc cgaaggtgcc gtgcggcacc agccagcggt ccggttcggc cagcagctcg
     6121 cacgcccggc agaggtcggc gtgcgggcgc ccggtcgcgg tgacgagccc gtggaggggg
     6181 aagtcgtgcg gcggataggg cgaggagcac ccgctgccgg gcgcgccggc ggtgccgtcc
     6241 tcctcgtgtg cggcggcggt cagcgccagc agcgcggcgg ggccgaggac gacggggtcg
     6301 ccggggcgga cgtcgccggg accggcggcg gccgcccagg gcagggagcg gggcgggtcc
     6361 gtgccgtcct gcaggtggag cacgcggtcg cggtcgcgga cgaggaggta cgtacgcgcg
     6421 gatacggcca cgcggcggcc gtcgcacgtg acgtccgtcg tgatgcggcc ggcctccacg
     6481 agcaggccgt cctcgccgag ggcgggtgcg gcgcggccgc ggagggcgcg gtggacggcg
     6541 agggcgtggc gccccgggtc cggctcctcg ccggtgccag gcggcgcggt cgtcgccgac
     6601 agcctccatg tgccgctttc gccggacgcg gcggtcatgg ccagccgggt gcgcgtctcg
     6661 ccggtcccgg cgtcgaggcg cgcgatgtcg tggctgcggg tgacggtgac ggcgggggtc
     6721 atggtgtgca ccgcaggcgg gagagccgga gggcgggcgc gcacatgccg acgtcgaaga
     6781 gcagctggcc gtccttgccg cacagggcgt tgtcgccgaa ctcggcgtgc gcgcccgtct
     6841 ccacgacgcg ggtgaggacg tcggcgcgct cgcgcaggcg gccgcggacg tattcgcccg
     6901 tgcggcggcc ggagcggatc agctcgccga gcaccaggcg ggcttcgagg gtggcgccgg
     6961 tgcggatccc gtccgcgagc cggtggacga ggagcccgtg gccggcgttc tcgacgagcg
     7021 ctccggtctc ggcgtcgccg ggccggcaga ccacgttcga catgcggggc accggccggt
     7081 gcagcaccga tgcggcgcgg ctgttggcgg tgggcatggc cgcctcggcg gcggcgctgg
     7141 agaggctgtg cagctggcgt acgagcctgc cctcgtgcac gatccgctgc cggccgaggc
     7201 agacgatgcc ttcgtcgtcg gtgtcgtagt gggccggtcc gccctcggcg agcgggtcgt
     7261 cgtccagggt gatcagctca ccggccacgc ggcagccgag ccggtgggcg agggcgggcg
     7321 tgccgccggg ggacgcctcg gcgaagtggc ccgccgcctc gtgcagcagg acgcccgcgg
     7381 cctggggcat gagcaccgcc gcgcactccc ccggctccgc ggcccgggcc gcgtcgacgg
     7441 cggccagcag ccgggcggcc gactcgcacc acgccgggtc ggtgagccgg ggcagcgccg
     7501 ggccgcggcc gctgcgcccg acggggacct cgtgcccgcc gggcgtgagc aggccgccgg
     7561 tcagggacca gacgcggcgg gcctgggggg cggtggtgcc gtgcgccgtc cccgcgacga
     7621 cgcggaccga ggagacctgc gagaactgca ggtcggcgcg gcctccgaag cggtcgcgga
     7681 gggcggtgag ggcggccagg acctcgtcgt ggtcgtccgg cggctcgggc tcggggaggc
     7741 cggtgcgcca gggggcgggc gggtcgccgg agaagatccg cgtgccgcgg cccgggcccc
     7801 ggtcgtggcg gcccatgcgg gtggacaggc ggtgggccga cgtcccgcgg gggccggccg
     7861 tcaccaggcc gccgacggcg cgctcgcagg cgacggtctc ccccgccgga gcctcggccg
     7921 gtatcgccgg ggcgtcagcg cgtatcgccc gggcgtcagc gggcatcggt gtcgccgttg
     7981 accggtgcct ccagcagcag gcccatcccg gccagcgagc ggaccagctc caggccgcgg
     8041 cggagcgtgg tgtccgggtc tccggcctcc tcggggaaga cctcggcgat gagctggcgc
     8101 gcggtgcgcc ggccgtcggc gcgttccagc aggtcgcgtg cgctgcggcc gagctggatg
     8161 gtctcgatct tgtcgctcgc gctcttccgg gtgacgacgt aactgctgcc gttcgcggag
     8221 cccttgccgt cctcggccgc gggttcctcc gccgggccgc gcagcatccg gtgcaggtcg
     8281 tgcgggaact cggcgctgag gaagtccccg gcgcggaggg cggattcggg gccgacgctc
     8341 ggtgcggcgg ggcgcggggg cggctcgggc aggtcggccg cggccagccg catcatctcg
     8401 tagcgcacga gggacgcggc cggcgagtcc tcgatgccga gccggacggt ctcctcctgg
     8461 gcgaagacca gcaggtcgcg cgcctcgctc tggtgacgga agcgggtccc cggcgcgtgc
     8521 tcggcgttgt actcctcgat ccaggcgacc cagcgctcgt accagtccat gggcgagtcg
     8581 tagtacggca ggagccgcgg ccacagggac gcgagaacga cgacgtggcc cgagagctcc
     8641 tcggcggcgt cgatcagcgc gtcgcccact tccgggcagg cgaagcggta gtcggtgcag
     8701 aacatgtcct tgtgctcgcg ccggtactgc tggatctgtg ccatgggccg gtcggtgacg
     8761 gggatgtcgt agtactcggc gggccggttg agggtgggcg cgtactgctt gtacatgggc
     8821 gactggtgca gcggcacgag cgtgaagagc tggctgcggc cctggccctc ctccaggaac
     8881 tggaagaagc gggtgagggt ctcggacatg gtttcgcggg tctcggtcgg gtagccgacg
     8941 atgaagccgg tgacgggacg gatgcccgcg gccttcgtcg cccggacgac ctccagggac
     9001 cgttcgagat cgaggttctt cttgatccag cgctgcatct tcggcgagcc gctctcgatg
     9061 ccgtaataga tctcctcgca gcccgccgcg cccatcttgt ccaggagttc ggcgtcgatg
     9121 aggtcggtcc gggtgctgca gccccaggtg acgccgaggt cgcgggcgat cacggcgtcg
     9181 cagaacttgt gggcccaggg gcggtcgcag gtgaagatgt cgtgcgagaa gttcacgctg
     9241 gtgcggccga aggcgtcgcg gacgtactcc agctgccgga tgatgtcgtc gatcggccgc
     9301 atgcggaact tgcgctccca gaagggtgcg gtggcgcaga aggagcagcg gaaggggcag
     9361 ccgcggccga cgtccaggta caggcgggcg cccttggaca tgtcgtaggc gtagtaggcg
     9421 ggccagggca gctcggcgag gtcctggaac agcggccgtt cggcgttgac gacggcccgg
     9481 ccgtccttgc ggtgggtcag gccgcggacc cccgaggggt cctggccggc gtgcagggtc
     9541 tccaggagct cggtgaaggt cgcctcgccc tcgccccgca cgatgaagtc ggcccagggg
     9601 aagcggtcga ggaactcggc gctgatgggg gtgacggccg gcccgccgag gcagatccgg
     9661 gtgtccgggg agcgcctgcg cagggcctgc ccgaggagga cggtgtggac gagcgagtcc
     9721 gcgtcggtca tcaggccgac cagggagtcg ccggccgcga gcacggaccg ggcgaggccg
     9781 tcgtagaggg cgtcgtcgtt ggggacggcg ccgtcgagca gcagctgatt ggtctcgacg
     9841 acctcgatcg cggcgggcgc cccggccgcg tcggcggcgg ccttgaggga cagcaggccg
     9901 acggggacga agttctgcat gggcggcggg tcgccgggcc gggtccgcag ggacatcccg
     9961 ccgtggttga ggtgcgggct ggtggcgagc gcgaccttca tcatgagcgc tccccgggta
    10021 cggtgctgtg ttcgccgcgg cgcagttcga cgcgcggctc ggccatgatg cgttcgcgga
    10081 agagctcttc ccggcgcagg atgctctgcc gctggaagtc gctggtgccg cagccgtcga
    10141 aggtgccgtt gaggatgctg gactggctcg ggcagcgccc ggtgcagaag tacttgtcgt
    10201 cgttgatggg gcagccttcg caggtgtcgc ggtagttgtc ccaggtgatc tttctgacga
    10261 gccagtcctc gctctcccag atcccggcga acggcgtcag ctggacgttc ccgccgcaca
    10321 gcaccttgtt cccggcgcag gtgctgcacg ggaagacgtc cccggcggag ttcacgtagc
    10381 agacgccgcg cccgctcatg cagcggcgcg tcgcgaagac catggtgtag aggaagtcca
    10441 gcaccttgcc cgcgcacagg ccgagggtgc ggtccttctc gcggccccac tcctcctcgt
    10501 cgatccagaa ccgggcggtc cgctcgacgt cgtgcatcga gctcgcgagg tcgtggtgga
    10561 gggcgccgcg gcccatcggg atgaacggga cgctgcgcag gctgacgtcg ttctccttcg
    10621 cccagccgat gatgacgggg aggtcgtcga cgttctcgtg ggtcgtggtg gtcatgatgc
    10681 tggtgttgaa tccccggtcc cggagttcgg cgagccggcg cgtgacgtag gcgaattcgc
    10741 cctcgttgcg gtatttcccc tgtccgtgca ggccgtcgat gctcatgctg atgatgacgt
    10801 cgtcctgcgg tatgcgggag aggatgcgtt cgccgagcgt cgtgccgttc gtggcgatgc
    10861 cgatgacgaa tcccaggtcg tacgcgcgct gcacgatgtc gcagaaatcg gggtgcatgg
    10921 tgggttcgcc gccggtcacg atcagcgaga agacacccat ggccgcccat tcgtcgagca
    10981 gccgcatgat gagctcggtg ggcaattccg agctgcgcgc ccggccgccc tcgacgaagc
    11041 agtgcgggca gcggagattg caggagcggg tgatctccag ccacaccatg gcgggtgccc
    11101 ggaaatggaa atccgtctcc acggagagtc tttcgacgag gtggtccgtg caccgttcgg
    11161 gtggttcgcc cgcacgcagc agggcttcgg cgccctcgtc gtacatggcc accgaaccgt
    11221 ccgggaacgc ggccagccag ccgaagtcct cccggcggta gcgaatcagc ggccgggtcc
    11281 tcggtggcag ccgccgggcg tattcgggcg tacaggacga aacgtgctgc agcaacgtac
    11341 ccctccatcg tctccgtcgt cgtccgtctc cctcgcgcgg gacggacgct ccctcgcgcg
    11401 cggcacggac gtgaaccgcc gggaccctcg cccggtgagc acgagagccc cggcggtcgt
    11461 cgggtgctcc ggtcccccgc tgctacttgg gggtaccgac ggtgctggcc gtggtggccg
    11521 tgcgctcttc gatgacggag atctcctcga cggcgcgctc gggcgagtcg gggacggacg
    11581 gcatgtcctg gggcgagatg tgcaggtggg cgatgcgcag ctcaccacgc gccccgcggg
    11641 tcaccacgag ggtctcgcgc aggtactgct gctcctcgcc gagggccacc cggcagtgca
    11701 ggctgacgag ggccgtgtcg ccgaggatcc ggatctcggg cgagagcagc tggctgcgcc
    11761 gggccgggcc ggcggagagg gtgaacaccc gctggaattc ctcacggctg tcgatgcggg
    11821 tgggcgacga cagaatgaag aaggtggcgt cgggggcgaa caggtcgaag tacccctggt
    11881 cgcagcggtc atatgccgac cggtactcct cgaggagctg ctggacggct tccctggtga
    11941 tggcgcccgc ggtcaccgtg ggcacgaaat ctatggtcat tgagcgattc ccttgttttt
    12001 cggctgctcc ggctgcgtcg actgcatgag ggaccggaaa gggacgtcgt gcgggagcac
    12061 ccccagcgga ggctgaggga gggtacctgc ggagaatttc tcactctcgc ccttgcatca
    12121 gatcgcaagg ctcacccagt cgctcgcatg ttcgctggta cccgactatc accgagggtg
    12181 agtgggctgt caatacccgg gaactccccg ggaaaggcgc ccagttggga ggtttgatcg
    12241 cggcctcgat cagcggtttt cggcacggaa tccgatattc acgcggggcg tgaattcggg
    12301 aatcccgttc cgcatacagg accgcccgcc ccgggcgccc ggacggccgt ggcgcagatc
    12361 tggcgccacg ggctggacga ccggccgcga ccggccccgg cccgcaggcc ccgggcggtt
    12421 tgcgcatggc gccacggcgg tgcgaggatg acgccatgga actcatgcgg tatgtcgaca
    12481 atctgcgcca ggaactcctg gtcgcagccg aggcgggcga cgcggaatcg cgtgaggtcg
    12541 ccgagcgtct cgtcgcgccg ctctcctccg ccgtccggct cgtgctgctc gacgccctgt
    12601 ccgccgccgc ggacgagatc accagcgatc tggcgccggg ctcggtcgag gtccggctgc
    12661 gcgggctcga cccgagcttc gtcgtcacgc tccccccggc cgaccacggc cccggcgacg
    12721 ccgagggcgg cttcgagcgc ccgcacgccg gtgcggtgcc ctcgctgccc gccgcgccgc
    12781 cggcgcccgc gggcggggag gacggcgcga cgtcccgcat caacttccgg ccgcccgagc
    12841 acctgaaggc acggatcgag gaggccgccg ggcgcgaggg cctgtcggtc aacgcctggc
    12901 tggtccgggc ggtgtccgcg atgctcgact tcgacgagca ggcgcgtcgt cccgagcgcc
    12961 gcgcgccgcg cggcggccag cactacacgg gctgggtgac ctgaccccgg ccggtaccgg
    13021 agcacgacca cccttccgac cagcggggac gacaccatgc ctgttttcga gacgccgcac
    13081 cccatcaccg tctccgtcga cctccccgtc ggagacgtcc gcctccgggc gggcgaccgc
    13141 accgacaccg tggtcgaggt gcgcccgagc gatccgggca gcgcggcgga cacgaaggcc
    13201 gccgaggaca cccgcgtcga gtacgccggg ggccggctgc tcgtcaaagg gcccaagccg
    13261 cgcgtcttcg gccgggccgg atccgtcgac gtgacgatcg gcctgccgtc ggattcggag
    13321 gtccagggga cgggccagat gaccgccttc cactgcagcg ggcgtctggg cgagtgccgg
    13381 atcaagacgt cgacgggcgg catccacctc caggaatccg gccggctcac cgccaccacc
    13441 tcgctcggcg acgtcacggc ggaccgggtg gacggcaccg ccgcgatcac gaccgggacg
    13501 ggcggggtac gggccggcgc gctgaccggc ccggcggtga tcaagaactc caacggggag
    13561 acctgggtcg gcgaggcctc ggcggacctg cgggtgcgct cggccagcgg cagcatcgcc
    13621 gtcggcacgg cgcacgcgga cctggaggcc aagaccgccc acggggacat ccgcgtcggc
    13681 gaggtcgtgc gcggctcggc ggtgctcgcc acgtcgagcg gccagatcga gatcggcatc
    13741 cgccccggca cggccgcacg cctcgacgta cggacgaagt tcgggcacgt ccacaacctc
    13801 ctgacggcct ccgacgggcc cggacggtcg gatgagaggg ccgaggtgta cgcgaccacg
    13861 tcggtcggcg acgtgacggt ccgccgcgcc gggggcgcgt gacgcggacg gcgccgccgt
    13921 agcccgcgcc tccacgtcca aggcaccgcg tctaaggcac cgcgtctaag gcaccaccac
    13981 gatcttgcag ccctccccgg cccggaagcg gtccatcgcc tcggggtacc gctccagcgg
    14041 cagccggtgg ctgatgaaca ccccggggtc gaggaccccg gccgcgaaca gctcggcggc
    14101 ccgctcgtag ctgtggagta ccgccatgga tccggtgatg gtgatctcgt ggtggtagat
    14161 gcggtacggc tcgatggtgg ccgtggccgc gagctcgctg acgccgaact gcaggaacgt
    14221 gccggccttg gcgacccgcc ccaggccgtc ctggatggcg gcggcgttgc cggtggcgtc
    14281 gatgaccacg tcccagccgc gcgcctgctc cagttcctgc gccgaggcgg cggtccgcgt
    14341 acagcccagg gcgcgggccg tcgccagccg cgcggggttg acgtcgacga cgtccacgga
    14401 gccggccccc gtgcgcttgg ccagctccag catcatcagg cccatcgtcc ccgagccgta
    14461 gatcagcacg tcggcgccga gccggctgcc gagcacgtcg tagccgcgca ccgcgcagga
    14521 cagcggctcg atgagcggcg cgtcgcgcac gtcgacgtgc tcgggcaggc gcacgcagtt
    14581 ggccgccggg gcgagggcgt actcggcggc accgcccgcc gcggtgacgc cgatcgcgcc
    14641 ccggcggtcg cacaggttgc cccgccccat gcggcagtag cggcactcct ggcagtagag
    14701 cgaggggtcg acggccaccc ggtcgccgac ccgcagccgg gtcacgccgg aaccggtgcc
    14761 gacgacctcc cccgcgaact cgtgccccgg tacgaccggc aggctcgcgg cgcaccctcc
    14821 ctgcacgatg tgcaggtcgg tgccgcacag cccgcacgcg gccacgtcga tcacgacctc
    14881 gtgcgggccc ggggccgggt ccgcgagcgt ggcgatacgg atccggcccg gggcttcgac
    14941 gacggcggcc ttcatttgac ggctcctagg gagaggccct ggacgagctt gtcctgggcg
    15001 gcgaagccgc cggccaggac cggcagcgag atgacgaccg aggcggcgca gacctgtgcg
    15061 aggaagaggc cctggctggt gatgaacccg gtcaggaaga ccggcgcggt ctgcgcggtc
    15121 accgcggtca gggcccgggc gaagagcagc tcgttccagc tgaagatgaa gcagatcagt
    15181 gcagtggccg cgatccccgg gccggccagc ggggcgacca cccggccgag gaccgcgggc
    15241 agccgggcgc cgtcgagtcg ggcggcctcg acgagggaga cggggatgtc ggagaggaag
    15301 gactgcagca tccacacggc gaccggcagg ttcatcgacg tgtggaggac gacgagcagc
    15361 cagatgttgt cgagcagcga ggtgtccctg gcgaacaggt acacgggcag cagcccggcc
    15421 accaccggca gcatcttcgt ggagaggaag aagaacagcg cgtcggtcca cttgcgcacc
    15481 ggacggatgg acagcgcgta ggccgcgggc agcgcgaggg tcaggacgag caccgtcgac
    15541 gtcactccgg ccgtggccga gttgatcagc gcgggccagg ggctcgtccc tcccccggcc
    15601 ccgaagaacg tgcggtagcc gtcgagggtc agggaagcgg cgaccgacgg ggggttggtg
    15661 gcggcgtcgc tctccgagtg cagggaggtg agcaccatcc aggccaccgg caggaagagg
    15721 acgaggcctg ccagccaggc cagcagcccc ggcaggaggc cgcggcagcg ggcccggcgg
    15781 gcctccggcg gcagggcggc ggcgtcggca tcggcggcgg tcatcctcgg gacacccctc
    15841 cccggaacag ggacgagacc acgcgcaggg cgaatgtcgc gatcacggcc gagccggtca
    15901 cgacgagcac tccggcggcg gaggcctgcc cgtactcgtg ggcctggtag aaggtccggt
    15961 agatcgcgta cggcagattc gcggtgccca ggctcccgga ggtgacggtg aacaccgcgt
    16021 cgaagttctg cacgatgtgg atcgcgccca ggagcgtgcc cagttcgagg taccggcgca
    16081 ggtgaggcag cgtcacgtac cggaagacct gccagtcgcc ggcgccgtcc agccgggccg
    16141 cctgcaccgt ctccggggag cggctctgca gcccggccag caggatgagc atcatgaacg
    16201 gcgtccactg ccacaccagc gcggcctcca ccgcgggcag cggcatcgag gagatccagt
    16261 ccggctgggg cgggctgtcg acgccgaaga gccggccggc ccaggtgagg gcgccgttga
    16321 gcagcccgta ctcggggttg tagagcacgt gcttccacag cagggcggcc gcgacgggca
    16381 cgagcaggaa gggtgcgatc aggagggtgc gcaccagccc gcggccgcgg aacgagcggt
    16441 cgagcagcag ggcgagcagc agtccgagga cgagactggt gacgaccacg gaggcggtca
    16501 ggaccatggt cgtgacgacc gcgtcccgca gaccggcgtc gtgcacgacg gcggtgtagt
    16561 tcgacaggcc ggtgaagcgg cgctcgccgg gccggagggc attccagtcg aagagggaga
    16621 tgaccagggt ggccgcgaac ggcagctggg tgaccgcgat caggaacacc agcgccggca
    16681 gcagcggggc acgggtggcc caggcccgca gggccggggg cttcggccgg gggccggcgg
    16741 tgcggggcac ggctccggcg cgggctgcgg gcgccgccgt cagcggatcg gtcatcggtt
    16801 gcggtactcc tcgccgatct tggccgccat cgcctgggac ttccgcagcg cctccccgac
    16861 ggaccggcgc ccggcgatgg cggcgctgat ctcctgggag accctggtgc ccaggtcgga
    16921 gaattccagg atgccgacga actgaatgcc gggggccggg cgcggctggg tgcccgggct
    16981 gcgcggatcg gcgctgccga tggcctcgcg ggtgacctcg gcgaaggcgc ccgccgcctt
    17041 gcggtagtcc tcgttcgcat aggtcgaggc ccgcttgccg gccggcgcgg cggcccagcc
    17101 ggcctccttg cccaccagcg cctcgtacgc cttgcccgac gcccaggaga tgaacttcca
    17161 cgccttgtcc gggtgcctgg cggccttctg cactccccag gcccaggtgt agagccagcc
    17221 ggaggacttc gtcctgtcca ccggggccgg tgcgtagccg atcctgccct tcaccgggga
    17281 cccggcggcc tccagcgatc cggcggcggc cgtcgcgtcg taccacatgg cggtcctgcc
    17341 ctgggtgagg ctgttgaggc actcggcgta gccggcctgg gcggctccgg cctcaccgtg
    17401 cttgcgcacg aggccgacgt agaactccgt cgccctgacg aactccggcg cggtgagctg
    17461 cgcccgccag tcctcgccga accaggtgcc gccgaaggtg ttgacgacgg tggtcagcgg
    17521 ggcgatcacc tctccccagc cgggctggcc gcgcaggcag atgcccttca tgccgggccg
    17581 tgcgccgtcg gccttcgcgg cgaggcctgc gacctgctcc caggtggggc gggcgggcat
    17641 ggtcaggcct ttctccgcga agacgtcctt gcggtacatg aggaaggacg actcgccgta
    17701 gaagggctcg gcgtacagcc tgccgtcgtc cgccgtcagc gagtcccgga ccggcttgag
    17761 gatgtcgtcc tggtcgaagg cggtgtcctg tgccgcgtac gcgtccaggg ggagcagcca
    17821 gcggttcttc gcgtagaagg ggacttcgta attgctgatg gtggccacgt cgtactggcc
    17881 cgtctggtgg gagaagtcct ggcccgtctt gtcgcggacg tcgttctccg ggagcagcgt
    17941 gtagttcacc ttgatgccgg tggccttggt gaagtgcgcg gcggtcagct tctgcaactg
    18001 cgccatctgc gggttgttga ccatgagcac gttgagggcg tcgccgccga aggctgcggt
    18061 gccgccggcc ccggcgcatg cggcgagcag tccggacgct gcggcggccg cgacgagcgc
    18121 cctcgggccg cgtggggttc ggtgggtcat cgcagggctc ccggtctggg gtggaggcgt
    18181 ccggtcgggt tccaggggcg ccggtcggca gggggccggt catacgcgga tgacctgggg
    18241 gcccatgagc gagtagcggt gcgcctcggc caggggcagc gccgtgtccg tgatgatcgt
    18301 ttcgaagtcg gagacgtccg cgaaccggca gaagctgccg gccccgaact tggtgtgcac
    18361 accggcgaac acccggcgcc gcgagacccg tacggcctgg gccttgacct cgccgacggc
    18421 ggggtcgggc gtggtcagcc cgtactcccg ggagatgccg ttggcaccga tgaacgccag
    18481 gtcgatcacg aacccggcga gcatgcgggt ggcccagtgg ctcacggtcg ccagggtgct
    18541 gccgcgcacc ctcccgccga gcagcaggac ggtgacgagt tcggcggacg ccaggctgct
    18601 cgccgccgcg agggaggcgg tgaccaccgt caggggacgg tcgcggggca gtgcctgcgc
    18661 gatcagctga ggggtgaacc cctcgtcgac gaagaccgtc tcggcgtccc cgacgacctc
    18721 cccggcggcg gccgcgatcc gctgcttctc caggacgtgc atggtggtcc ggaaggccag
    18781 cgtggtctcg tagcccgcgc tctccacggg atacgcgccc ccgtgggtgc gccggaccag
    18841 cccgtgctcc tccaggaccc gcaggtcgcg gcggacggtc tctctcgaca caccgaagtc
    18901 gacggcgagt ttgccgacgt cgaccattcc gttgcgccgg gccagttcga gcatcccccg
    18961 tcttcgctct tcggcttcca aggtgcactc cctgccgcgt ggtggtggca ccgcgatgcc
    19021 cgtacgggcc tccgggtgcg tttctacaag tgcccgggtg gagtgggcat gcccggcgca
    19081 ggggagttcc tgcccggatc cgcccgccgg ggaacgcgaa gcgatgcggc gggacctggc
    19141 cttcgccggc cggccccggc gttcccgcgc ccggtcgcgg cggtgcgggc aaccgcttca
    19201 tgaccgtccc gctccttccg ctttcccgtc cggcggtcgg agagggggtg ggcggagcgc
    19261 cgggtccaac gacgacaagc gtggccggta ttcaaccggg ccgttccggc gcgccccggc
    19321 ctctcaggcg tccctggccg cccctttgcg ggttgtcatt tcttttcggc gcgtcgttcc
    19381 gggcacccct gaaccccggt acgggcattc gccgtgcccg ctcggtcatc gcccgtgcaa
    19441 agcgcctgcg ttcagggccg gttgatgatt cggccaaccg tcccggcgtt gattgacgct
    19501 gcttgagggc cggtgccacg ctttcttcat cgtcgatgac gcacaccggg aagatgtgaa
    19561 gaagcaagtg aagaagcgca tgcagaagca agtgaaggag caatcgcggt gaaaatcgta
    19621 aggaatcgtc ccggccccct caccggcctc gacgtattcg tcggcggacc gatccagcac
    19681 gccattctcc ccggcgggtt caccgcctcg ctgcaggatg cgatctcgac cgcgatcgcc
    19741 gtcgtcgaag agaacggcgg gaacatattc tccgcccacg tcgtggagaa gttcggtgcg
    19801 gagaccgatt ccttcacccc ggagcaggtg tcggtgcgcg attaccgctg gatgcggaag
    19861 tgcgacgtct tcgtccccgt tctccccctg ctggacgaca agacgctgca ccggacggac
    19921 ggcacgcacg tggaactcgg ctgggccacg gccatgggcc gccccgtcgt cctcatcacc
    19981 cggcagccct tcgccgaatc ggcgagccac cttctcaagg gcctgcaccg tgtgggctcc
    20041 gtacacgccg tcgacttcga cgaattcgcc gggaagccgg acctgctgat cgacgccatc
    20101 gtgtcggcca ccggacagca gcagaaagcc gtccaggccg gcatccccgc ctgacacctc
    20161 ccggaggacc gtgtgtccgc tgttcacgta ctgggcctga ggatcaggaa cgccgtgatc
    20221 gtcgggtccg ggctcctgac ggaccaggag cgcaacatcc gcaggctcct ggagaccggc
    20281 gcaggagccg tggtcaccaa gaccattcac cccagcccgc cgagggggct ggacgagcgg
    20341 ctcgtgcggc tgcccgtggg catgctcaac agcaccacgt actcgaagcg gacggtcgac
    20401 cactggctca tggtgctccg ctccttcgcc caggacgacc tgccggtcat cgcctcgctg
    20461 cacgccgaca ccccccgcga gctgggcgcg ctggccgccg aggtgcaggc cacggggtgc
    20521 cgggccctgg agctcggcat ctcgtgcctg aacgaggggc cggggctcac cgacgacact
    20581 ccggagcggg tgtacgccta cgccgccgcg acgcggagcc ggacctcgct gcccttctcg
    20641 gtgaaactgg ccatcggcga gggcctggag gcccgggtgc gtgcggcgct ggccggcggg
    20701 gccgacgccg tgaccgtgag cgacacgatc ccgggggcgg ccgtggtgcc ggacaccggc
    20761 gagctggagc tgggcggcac cttcggctat tccggccccg gcatcaagcc gctcgtcctc
    20821 gcggccgtct ggcgcctgcg caagcgcggc ttcgatctgc ccgtgctggg ctgcggaggc
    20881 gtcgcctcgg gccgcgacgt cgccgactac ctgagcgtcg gcgcccaggc cgtgcaggtc
    20941 tacacggcgc tgcacaccga cacgtacgcc accttggacc gcatcgtcgg cgaagccgcg
    21001 ggcctcgcac agggccccct ggaggcggcc acatgagcag cctgctcccg gacccctgct
    21061 cctcccccgc tcccgtctcc ggttccttcg ccgatctcac cagctcctgc gtcgaggagc
    21121 gggtggccgc ggcccgtacg ctggtctggc cgatcggggc caccgagcag cacggtccgc
    21181 acctcccgct ctgcgtggac accgtgctcg ccgaggagtt cgcccggcag ctcgcggccg
    21241 acctgggcgg gatcaccctg cccgtgcagt cggtcgccgc ccgctcgctg ccgcagagcg
    21301 gcggcgggct gtcctttccc ggcacggtgt acgtg
//
