LOCUS       NZ_BMUT01000001        21373 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces hiroshimensis strain JCM 4586 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUT01000001
VERSION     NZ_BMUT01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces hiroshimensis
  ORGANISM  Streptomyces hiroshimensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1281729)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 90X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650335.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:32:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,830
            CDSs (total)                      :: 6,745
            Genes (coding)                    :: 6,620
            CDSs (with protein)               :: 6,620
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 25 of 125
            Pseudo Genes (incomplete)         :: 107 of 125
            Pseudo Genes (internal stop)      :: 4 of 125
            Pseudo Genes (multiple problems)  :: 11 of 125
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 575341
            Orig. end                         :: 596714
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUT01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21373
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="triceptide"
                     /region_number="3"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..21373
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21373
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11373](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11373)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     gene            complement(925..1437)
                     /locus_tag="IE241_RS02270"
                     /old_locus_tag="GCM10010324_04670"
     CDS             complement(925..1437)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055699.1"
                     /locus_tag="IE241_RS02270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04670"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_190019847.1"
                     /transl_table=11
                     /translation="MPDKEPDQKPGQESDQESGTADADTGQPSGKDQERAAADLAATVS
                     QLMRRLRVASPQGALTPSQRAVLGRLDTAGPATTAELARAELVRPQSMRVIVARLEELG
                     LVTRSPHPTDGRQVLFSLTEHGDEAIASVRHSKHAWLADAMAHRLTPEEQRALADATLL
                     LKRLVEE"
     misc_feature    1443..1461
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.89"
                     /tool="antismash"
     misc_feature    1571..1586
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.61"
                     /tool="antismash"
     gene            1630..2472
                     /locus_tag="IE241_RS02275"
                     /old_locus_tag="GCM10010324_04680"
     CDS             1630..2472
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578982.1"
                     /locus_tag="IE241_RS02275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04680"
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="WP_190019848.1"
                     /transl_table=11
                     /translation="MANVVRAALVQATWTGDTESMLAKHEEHARAAAAQGAQVIGFQEV
                     FNAPYFCQVQESEHYRWAEPVPDGPTVRRMQELARETGMVIVVPVFETEGPGFYYNTAA
                     VIDADGRYLGKYRKHHIPQVKGFWEKYYFAPGNLGWPVFDTAVGKVGVYICYDRHFPEG
                     WRQLGLNGAQLVYNPSATSRGLSGYLWKLEQPAAAVANEYFIAAINRVGREEYGDNDFY
                     GTSYFVDPRGQFVGDVASDTKEELLVRDLDFGLIEDVRQQWAFYRDRRPDAYDGLVRP"
     gene            2469..3809
                     /locus_tag="IE241_RS02280"
                     /old_locus_tag="GCM10010324_04690"
     CDS             2469..3809
                     /NRPS_PKS="Domain: Aminotran_3 (37-375). E-value: 2.1e-74.
                     Score: 242.5. Matches aSDomain:
                     nrpspksdomains_IE241_RS02280_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537503.1"
                     /locus_tag="IE241_RS02280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04690"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_190019849.1"
                     /sec_met_domain="Aminotran_3 (E-value: 8.7e-83, bitscore:
                     274.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSAPGPGGSPATHLHARHRAVMPEWLSLYYREPLELTHGEGRHV
                     WDARGRRYLDFFGGILTTMTAHALPEVTKAVSEQAGRILHTSTLYLDRHMVELAERIAA
                     LSGIPDARVFFTTSGTEANDAALLLATSYRRSNQILAMRNSYHGRSFSAVGITGNSSWS
                     PTSLSPLQTLYVHGGVRTSGPYAHLSDADFTAACVADLTDMLGQTHGRVAALIAEPVQG
                     VGGFTSPPDGLYAAFREVLAERGILWITDEVQTGWGRTGDHFWGWQAHAEHGPPDLLTF
                     AKGIGNGMSVGGVVARAEVMNCLDANSISTFGGSPVTMAAGLANLTHLLEHDLQGNARR
                     VGGLLIERLRAVTAGFPAVREVRGRGLMIGIELVEHDGSPSPEAASLVLELAREEGLLI
                     GKGGREANVLRIAPPLSLTITEAEEGAAALETVLRQVQFTIAGKERP"
     aSDomain        2580..3593
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE241_RS02280_Aminotran_3.1"
                     /evalue="2.10E-74"
                     /label="IE241_RS02280_Aminotran_3.1"
                     /locus_tag="IE241_RS02280"
                     /protein_end="375"
                     /protein_start="37"
                     /score="242.5"
                     /tool="antismash"
                     /translation="THGEGRHVWDARGRRYLDFFGGILTTMTAHALPEVTKAVSEQAGR
                     ILHTSTLYLDRHMVELAERIAALSGIPDARVFFTTSGTEANDAALLLATSYRRSNQILA
                     MRNSYHGRSFSAVGITGNSSWSPTSLSPLQTLYVHGGVRTSGPYAHLSDADFTAACVAD
                     LTDMLGQTHGRVAALIAEPVQGVGGFTSPPDGLYAAFREVLAERGILWITDEVQTGWGR
                     TGDHFWGWQAHAEHGPPDLLTFAKGIGNGMSVGGVVARAEVMNCLDANSISTFGGSPVT
                     MAAGLANLTHLLEHDLQGNARRVGGLLIERLRAVTAGFPAVREVRGRGLMIGIELVE"
     gene            3806..5206
                     /gene="hydA"
                     /locus_tag="IE241_RS02285"
                     /old_locus_tag="GCM10010324_04700"
     CDS             3806..5206
                     /EC_number="3.5.2.2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hydA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714217.1"
                     /locus_tag="IE241_RS02285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04700"
                     /product="dihydropyrimidinase"
                     /protein_id="WP_190019850.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1e-22, bitscore:
                     76.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTAIRGGLVITAAEETSADVLVEDGKVAALAASGSAFAQGWHA
                     DRTLDATGKYVIPGGVDAHTHLDLPFGGTASSDDFETGTRAAAWGGTTTIVDFAVQSRG
                     QALREGLDRWHAKAAGRCAVDYAFHMILSDVNESSLKEMDLLIAEGVTSFKLFMAYPGV
                     FYSDDGQILRAMQRAAGNGGLIMMHAENGIAIDVLVEQALAAGRTDPRYHGEVRKALLE
                     AEATHRAIQLARVAGSPLYVVHVSAEEAVAELAQARDKGLPVFGETCPQYLFLSTDNLA
                     EPGFEGAKYVCSTPLRPREHQAVLWRGLRTDDLQVVSTDHCPFCFSGQKELGRGDFSKI
                     PNGLPGIENRMDLLHQAVVDGHITRRRWIEIACAAPARMFGLAPHKGTITPGGDADIVI
                     YDPHAEQTLSAATHHMNVDYSAYEGKRVTGQVETVLSRGETVIEQRKFTGRAGHGRYVP
                     RATCQYLT"
     gene            5248..6246
                     /locus_tag="IE241_RS02290"
                     /old_locus_tag="GCM10010324_04710"
     CDS             5248..6246
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847702.1"
                     /locus_tag="IE241_RS02290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04710"
                     /product="TIGR03842 family LLM class F420-dependent
                     oxidoreductase"
                     /protein_id="WP_190019851.1"
                     /transl_table=11
                     /translation="MDFGLVLQTDPPATAVVDLMRRAERSGFRYGWTFDSSVLWQEPFV
                     IYSRILEHTERLVVGPMVTNPSTRTPEVTASTFATLNDMYGNRTVCGIGRGDSAMRVAG
                     RKPNTLASLRESIRVIRDLAEGREADVGGTALKIPWIRDGRLPVWMAAYGPKALALAGQ
                     EADGFILQLADPFLTEWMIKHVREAAAEAGRDPAAVSICVAAPAYVGDDLAHAREQCRW
                     FGGMVGNHVADLVERYGEHSGLVPEALTAYIKQRHGYDYSHHGRAGNPSTDFVPDEIVD
                     RFCLLGPVEAHRERLEHLRELGVDQFAVYAMHDAKEATIDAYGEHLIPALS"
     gene            complement(6333..>6854)
                     /locus_tag="IE241_RS02295"
                     /old_locus_tag="GCM10010324_04720"
                     /pseudo=""
     CDS             complement(6333..>6854)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675961.1"
                     /locus_tag="IE241_RS02295"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04720"
                     /product="biotin/lipoate A/B protein ligase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="FIEPGNTITYSLCVPDALVQGLSFADSYAYLDDWVLGALEGMGVK
                     AWYQPLNDIATESGKIAGAAQKRLVGSAGAVLHHVTMAYDIDADKMLDVLRIGKEKLSD
                     KGTKSAKKRVDPLRRQTGLPRAGVIEKMIESFRGRYGLTAGSVTPEEMARAEELAATKF
                     SSAEWTARVP"
     gene            complement(6896..7231)
                     /locus_tag="IE241_RS02300"
                     /old_locus_tag="GCM10010324_04730"
     CDS             complement(6896..7231)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS02300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_04730"
                     /product="hypothetical protein"
                     /protein_id="WP_190019852.1"
                     /transl_table=11
                     /translation="MELGEYRRVGDRPPPTPIERPDNATRFLANTLANVAAWRAAEAAQ
                     TPCEGAASELAARFTPQEFEHVVRLLADDGTPASMALLQALSNEDEERIGDVSAGEWVS
                     RPAPSLR"
     misc_feature    complement(7148..7150)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7272..8327)
                     /locus_tag="IE241_RS02305"
                     /old_locus_tag="GCM10010324_04740"
     CDS             complement(7272..8327)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675961.1"
                     /locus_tag="IE241_RS02305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04740"
                     /product="biotin/lipoate A/B protein ligase family protein"
                     /protein_id="WP_190019853.1"
                     /transl_table=11
                     /translation="MHGEYKVPGGKLVVVDVEVRDGALRDVRVAGDFFLEPDEALFDIN
                     RALEGANADLPAQELAARIDAALPEGTVMFGLTSEAVGVAVRRALANATDWHDYDWQLI
                     HEGPQSPALHMALDEVLTAEVAAGRRPPTLRVWEWESPAVIIGSFQSLRNEVDMESAAR
                     HGMTVVRRISGGGAMFVEPQSTITYSLYVPDSLVQGLSFADSYAYLDDWVLAALGDMGI
                     KAWYQPLNDIATESGKIAGAAQKRMVGENGAVLHHVTMAYDIDADTMLEVLRIGREKLS
                     DKGTKSAKKRVDPLRRQTGLPRTEVIDRMVASFRDRYGCSVGEVTEQELSRAQELAQSK
                     FSSQEWTARVP"
     gene            complement(8483..9217)
                     /locus_tag="IE241_RS02310"
                     /old_locus_tag="GCM10010324_04750"
     CDS             complement(8483..9217)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS02310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_04750"
                     /product="hypothetical protein"
                     /protein_id="WP_190019854.1"
                     /transl_table=11
                     /translation="MAVSLAFGQCGSLRERCEIGSVRLSHDEAEYDDGAVVPAGDWRPL
                     NMREAQWFEAEPGTPDGTLIELVREPLPVIRAEEVSDIHATAADLYPFADRCPADFLGC
                     VTNPGDARTTTEDPATGRRLGLHVDNWDRLPYGARGDGRRRLCLNLGPGVRYFLLGDRD
                     IEEIYRLVHPDPEHHYPHTDDVRRYVTQGRPLQCLRIRLDPGDGYLAPTELLPHDGSTL
                     GGKQPSTAAFWLGRWPAGTGTL"
     gene            complement(9245..9931)
                     /locus_tag="IE241_RS02315"
                     /old_locus_tag="GCM10010324_04760"
     CDS             complement(9245..9931)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024986.5"
                     /locus_tag="IE241_RS02315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04760"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_190019855.1"
                     /transl_table=11
                     /translation="MESRKVRRVSVTLPALDEPGLYLSNVQSLESGRGRVAEFQYADMD
                     LRELDLVGTHLLDGRIQRVRTQRARFHEVRADSVQFSDCDLSSLKWSDGKLSRVTFSNC
                     KLMGALLEDVALDNVLFENCKFDYATLDRVRATGPVIFSKCTLRETTVRACDLGSVAIE
                     ACDLRLAEFEGGKYRDCDLRGNDLSTLRGTAALKKVLIDRAQVAQLADALAAELEVTYG
                     EDLDDE"
     gene            complement(10001..10195)
                     /gene="amcA"
                     /locus_tag="IE241_RS02320"
                     /old_locus_tag="GCM10010324_04770"
     CDS             complement(10001..10195)
                     /codon_start=1
                     /gene="amcA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041721.1"
                     /locus_tag="IE241_RS02320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04770"
                     /product="multiple cyclophane-containing RiPP AmcA"
                     /protein_id="WP_190020479.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLLEQLTATDAPVVRELIAAFGRPQGGPIHAKFDNRPTWDNWAK
                     EPPVTFNNQPTWDNWNKKK"
     misc_feature    complement(10187..10189)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10192..11373)
                     /gene="amcB"
                     /locus_tag="IE241_RS02325"
                     /old_locus_tag="GCM10010324_04780"
     CDS             complement(10192..11373)
                     /codon_start=1
                     /gene="amcB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041718.1"
                     /locus_tag="IE241_RS02325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04780"
                     /product="cyclophane-forming radical SAM peptide maturase
                     AmcB"
                     /protein_id="WP_308433607.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.3e-50, bitscore:
                     168.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-14, bitscore: 51.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPRKRRGSMTQRCGSRPHRRYGRWFARKPQTVVVQPTSFCNMGC
                     FYCYLRDKGLKNDMLPATAAAVAESLAGLASIGHPLGLVWHGGEPLTLGTEKFSALLAP
                     FETLRQDGRMHHYVQTNATLVTPAWCDLLEEFEFRVGVSIDGPAALNTQRVDLRGRPAF
                     ERIMRGVGLLRERGIPFSVIAVVGREGIGHPEELLDFVATLGCHSVGFNIEETEGVNTE
                     RRPPTRDQAEEFWRRVLAWSRSHRGPVIRELERISEYLSLARSGQKDDWDNRLLDPIPT
                     VTWNGDVVLLSPELADTSDSAYADFLAGNVREKTIAHMLREAPHLRYVREFLTGLERCQ
                     AECEFFDFCRGAQAGNRYFENGSLATTETNYCRVSRQALVMALSTTAKKEQIA"
     misc_feature    complement(10501..10503)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11605..11856)
                     /locus_tag="IE241_RS02330"
                     /old_locus_tag="GCM10010324_04800"
     CDS             complement(11605..11856)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS02330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_04800"
                     /product="hypothetical protein"
                     /protein_id="WP_190019857.1"
                     /transl_table=11
                     /translation="MSMKAERPDLSVAYRYLVTTPHASGPGHDYVAPADAPGPSCRTCR
                     LLDADLAKAIRSGDVAAETRSARHRVAHWSSMHRTVQW"
     gene            complement(11853..12137)
                     /locus_tag="IE241_RS02335"
                     /old_locus_tag="GCM10010324_04810"
     CDS             complement(11853..12137)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE241_RS02335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010324_04810"
                     /product="hypothetical protein"
                     /protein_id="WP_190019858.1"
                     /transl_table=11
                     /translation="MSTTAHVKTREIVKDARGLRAIWRYVLHRIVVHSDTITYGAQCLA
                     CEWTVQRSDDAAMHQACMRHTGRQPDHTAFWTYCRAMAYVQPATQGERR"
     gene            complement(12851..13696)
                     /locus_tag="IE241_RS02340"
                     /old_locus_tag="GCM10010324_04830"
     CDS             complement(12851..13696)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845068.1"
                     /locus_tag="IE241_RS02340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04830"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_190019859.1"
                     /transl_table=11
                     /translation="MPISPSSSAQAAREAIAGRLRDIRKDAGLTGHELATRAGWHASKS
                     SRIENARTPPSDEDVRTWCRVCGADDQADDLIAANRSADSMYVQWKRLQRTGSRRLQES
                     RVPLYESTQQFRVYCSNVIPGLLQTEAYATALFALISRAQGTPDDSAEAAAARVARSKV
                     IHKGEHRFALLVEESVLRYRIGDAETMAGQLGYLLTVMSLPSVSLGVIPFAASRSMWTL
                     ETFMIFDQEQVQVELLTAAVNIRAPGEVEQYAQAFTDLGELAVYGRQARALITSAIDAL
                     "
     gene            complement(13720..14247)
                     /locus_tag="IE241_RS02345"
                     /old_locus_tag="GCM10010324_04840"
     CDS             complement(13720..14247)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061116.1"
                     /locus_tag="IE241_RS02345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04840"
                     /product="DUF6879 family protein"
                     /protein_id="WP_190019860.1"
                     /transl_table=11
                     /translation="MRQNDVPSFSELLTSARHSAIHLEMRDVYAVEQENGEFEAWKAGH
                     RLDVEDRDSWWRPWLDLVQETVQRGVVMRRARIVSEPVTDYIRFEHSSTFTNVAAGELV
                     RWLPRRQTFDLALPGVDFWLIDERIVRFNHFSGDGVDTEPQVSEDPDVIKLCATAFEAV
                     WDRGIPHEQYQI"
     gene            complement(14177..14461)
                     /locus_tag="IE241_RS33960"
                     /old_locus_tag="GCM10010324_04850"
     CDS             complement(14177..14461)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999349.1"
                     /locus_tag="IE241_RS33960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04850"
                     /product="hypothetical protein"
                     /protein_id="WP_229898690.1"
                     /transl_table=11
                     /translation="MALEFIGIDPSTNDGNCPAAWVDKANADLLFQGWKPDEETEEECR
                     ANSPRPDHEAVVRVPVRMVPIIRKACDEAERRAQLLGAADQREALGDSP"
     misc_feature    14455..14467
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.66"
                     /tool="antismash"
     gene            complement(14638..14904)
                     /locus_tag="IE241_RS02350"
                     /old_locus_tag="GCM10010324_04860"
     CDS             complement(14638..14904)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019888713.1"
                     /locus_tag="IE241_RS02350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04860"
                     /product="hypothetical protein"
                     /protein_id="WP_190019861.1"
                     /transl_table=11
                     /translation="MTGPAPADAAAVALELERLRGTMEAGFARVDGALALLVQRSDQSD
                     RQLADHDKRLDALERNRWPLASLAAVISLVTLALTIWQATPAH"
     gene            complement(14901..15152)
                     /locus_tag="IE241_RS02355"
                     /old_locus_tag="GCM10010324_04870"
     CDS             complement(14901..15152)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019888714.1"
                     /locus_tag="IE241_RS02355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04870"
                     /product="hypothetical protein"
                     /protein_id="WP_190019862.1"
                     /transl_table=11
                     /translation="MTDATRRTIRTTVQTTITLAALLPVIIDASGILSTLPWAAGALAV
                     AAGLTRIMAIPGVQSLMPAWLRTHPRATLPTDDREGSA"
     gene            complement(15250..17241)
                     /locus_tag="IE241_RS34755"
                     /old_locus_tag="GCM10010324_04880"
     CDS             complement(15250..17241)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017102.5"
                     /locus_tag="IE241_RS34755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04880"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_308433608.1"
                     /transl_table=11
                     /translation="MAEYFYPFDSGAGTTVTSTQWSHMTSMWQTDGVRAPRTGEPDPLG
                     ATTTGQDMTITLAPGHATVQGHHYHADAPQNIVVSPNTGTTPRTDRITVRLDRTAQRIA
                     IAYLTGTPATKPLPPTLAQGQDGIVDVPLVRITVAPQTGAIRPADVIDERVFTLTQAVY
                     ANAGARLAALETPVPGKLAYLQDEQRLELRTESAWVPLSPGPWNPLPLPHDVKAHGGNP
                     SWRIVNGTVELCGSVERKDGRDFNVADSWLLATLPPAAQPHYMRSFICATSRNDNTHNS
                     IRVDVTSNSDPYPGQLQAMVLSPVRWIYLDSIRFAVDTTPPPPRNGGWDEISKAAYEAA
                     AKAVQEASRYAQEAARKAAEEAANSGKPPPDQNDEDKDSMPVARHLINIARREVGYHEG
                     RNSDGHWNNQEKYAPAVPGLEWAQGQAWCHTFVSWCFQQAGAKSLAPVTASCSAGVEWF
                     KQRDQWSDYPVIGGVVYYGDGGGEHVGICIAYTDDEITTVEGNTNDTGASEGDGVYLRT
                     RPRKSDRIYGYGIPTYPEGTVLADPLRQGQKGVVFFAHQADEHDIPAGRTTAGSGGAAV
                     TGGGFEPFPGEAWFKSGPTSPIITAMGRRLVAEGCGAYQQGPGPDWSDADRESFRRWQR
                     KLGNSPEFCDGWPGPRQWDALKVPRVSK"
     gene            complement(17258..18499)
                     /locus_tag="IE241_RS02365"
                     /old_locus_tag="GCM10010324_04890"
     CDS             complement(17258..18499)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025945.5"
                     /locus_tag="IE241_RS02365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04890"
                     /product="hypothetical protein"
                     /protein_id="WP_308433628.1"
                     /transl_table=11
                     /translation="MIPLRRYRVDVRDAALRRVGQVDAYTSLDVIVRHLDVGTWSLTLP
                     ATHPQARLLTTGQGVIIWPETTAGGGTGEAAAEPLLSGPVTKIRHDWSSSTGTGGTLTF
                     SGTCDNAPLGDRLAFPDPSRAPDNGNGRYSVDYWVRQGPAADIVRELVAANLGGRALPG
                     RRVAGLDTTPPPGTPAATGPAATARLRFDTVLSAVQTLATGAGLSVRIVQPDPTTARLA
                     LAIAPVRDLSREVRLSPQFGNLSAYSYELTAPKATRAVVAAQGQGADRFFWQWTTPDAE
                     RDWHRTAETFVDQRDTPVPARLDASDPQYTALAEAAARALEQSGQQAELSLSPIDTPQM
                     TYGRHYQVGDTVTVTTAGGVDLAYPVREVHVSDSAETTTVQATVGTANATKTPALYGQV
                     RRLWQAVHQLNTRH"
     gene            complement(18496..19566)
                     /locus_tag="IE241_RS02370"
                     /old_locus_tag="GCM10010324_04900"
     CDS             complement(18496..19566)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF046370.1"
                     /locus_tag="IE241_RS02370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_04900"
                     /product="phage tail domain-containing protein"
                     /protein_id="WP_190019864.1"
                     /transl_table=11
                     /translation="MRALAELNSPSAVVADSGAWTDRDATDGTSAPDQPPAVTLTTADG
                     TEFLLTASLAQVGACIAILPGPTGMDAPPWQASVSEYAGLDGGQVVKTRAATRRINLPL
                     LLWAPTRPELLALRRRLITAVMAGPGTLRVAEADGSARTIGVQYLGGLEGDESSDNAGL
                     TYTRYGLQLVAPDPYWAGPLRTAAFRVHGGTPHFLSRLPATASGPAGDDTTEAAFFPLR
                     IGASVIGEDGVPISVTSDTEAWPVWRITGPLGHQDAGQPAVPLRLSNTTTGKSLALNYA
                     VAAGEVVVIDTRPGIKAVYREAPGGGQGENLWPHVTGGAALWPLVPGTNTVAVTAAGAD
                     DRSAVTLTYQSRHYGA"
     misc_feature    19764..19778
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.15"
                     /tool="antismash"
     misc_feature    21102..21122
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(21289..21303)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.71"
                     /tool="antismash"
     misc_feature    21292..21305
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.51"
                     /tool="antismash"
     misc_feature    complement(21306..21321)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.37"
                     /tool="antismash"
ORIGIN
        1 cggcggccgt ggtgagcggg gcgcgcaggc ccttcgtccg ggcgccgagc agcgagcaga
       61 cggccgccgc gagggacatc ggcagcatga ccagaccggc ctggaaggag gtgcagcccc
      121 gggcctcctc cagccattgg gcgtatccgt acagggcgca gtagatcgtc aggtaggcga
      181 gcccgtggcg gaggtaggtg cgcaggaggg cgtggcgcgt cggggagtcg ccggacgggc
      241 agccggcggg ctgctgcggc tgtacgggcc cctgctgcac ggagccccgc acaggttctg
      301 cagggccggt gcggtcgtgc ggcagccacg gcagggccac ggccagcgcc agcagggcga
      361 gcggcacgtt gaccgcgaag atgccccgcc agcctgtggt cgcggtgagg agcccgccga
      421 gggtggggcc gagggccgcg ctgcccaggg cggcgagcga gaggcggccc atcacggggc
      481 ggggtgcggg gcggccggtg cgcagggact cggcgcgcag catcgccatc gcggcggggt
      541 aggcggccga ggtgccgagg ccgagcagca cacgggcggc gatcagccag ccgaaggcgg
      601 gcgccagcgt gccgagcagg ccgcccgcgc agacgatggc gaggcccgcg aggaagacgc
      661 ggcgggggcc gagggagtcg gcgaggcggc ccatgacggg ctggccgacg gcgctggtga
      721 ggtagaggga ggacaggagc cagcccgtgc cggaggggcc ggtgccgaag tcgcggccta
      781 cggccaccag accggtggcg atcatggtgc tgttgagggg gttgaggacg gcaccgagga
      841 gcagcggcgt catcaggcgc gcgccgaagc cctcgtccgg ggcggcgccg gggccgcggg
      901 cgcgcagggg cgcccttaag gccttcactc ctccaccagg cgcttgagca ggagggtggc
      961 gtcggcgagg gcccgctgtt cctccggggt gagccggtgg gccatggcgt cggcgagcca
     1021 ggcgtgcttg gagtgccgta cggaggcgat ggcctcgtca ccgtgctccg tgagggagaa
     1081 caggacctgc cgcccgtccg tgggatgcgg ggagcgggtc accaggccca gctcctccag
     1141 cctggcgacg atgacgcgca tggactgcgg tcggacgagc tccgcgcggg ccagctcggc
     1201 ggtggtggcg ggccctgcgg tgtccagacg gccgaggacg gcgcgctgcg agggggtgag
     1261 cgcgccctgc ggggacgcca cgcgcaggcg gcgcatgagc tgggagaccg tcgcggccag
     1321 atcggcggcg gcgcgttcct gatccttgcc ggacggctgg ccggtatccg cgtcggccgt
     1381 gccggattcc tggtcggatt cctggccggg tttctggtcg ggttccttgt cgggcatgcg
     1441 tccaccgtaa atatcgacag gcaaacttgc aagtttttct gtgttcttat gcgcaagccg
     1501 agttatccac aggacgatcg acggtcttgc cgcgcggcgt gccgcgtcct acggtcgcaa
     1561 ccacacgtgg atctacacgt gtcagcctgg ccggtcggcc cggctgacgc ccccgtgaag
     1621 gagcagctca tggccaatgt cgtccgcgcc gctctggtcc aggccacctg gaccggcgac
     1681 accgaatcca tgctcgccaa gcacgaggag cacgcccgcg cggccgccgc ccagggcgcg
     1741 caggtgatcg gcttccaaga ggtcttcaac gccccctact tctgccaggt gcaggagagc
     1801 gagcactacc gctgggccga gcccgtcccc gacgggccca cggtccgccg gatgcaggag
     1861 ctggcccgcg agacgggcat ggtgatcgtc gtgcccgtct tcgagaccga aggccccggt
     1921 ttctactaca acaccgccgc cgtcatcgac gccgacggcc gttacctcgg caagtaccgc
     1981 aagcaccaca tcccccaggt caagggcttc tgggagaagt actacttcgc cccgggcaac
     2041 ctcggctggc ccgtcttcga cacggccgtc ggcaaggtcg gcgtctacat ctgctacgac
     2101 cgccacttcc ccgagggctg gcgccagctc ggcctcaacg gcgcccagct cgtctacaac
     2161 ccctcggcca cctcccgcgg cctctccggc tacctctgga agctggagca gcccgccgcg
     2221 gccgtcgcca acgagtactt catcgccgcc atcaaccgcg tcggccgcga ggagtacggc
     2281 gacaacgact tctacggcac ctcctacttc gtcgaccccc gggggcagtt cgtcggagac
     2341 gtggcgagcg acaccaagga ggaactcctc gtccgcgacc tggacttcgg cctcatcgag
     2401 gacgtccggc agcagtgggc cttctaccgc gaccgcaggc ccgacgccta cgacgggctg
     2461 gtccggccat gacctccgcg cccgggccgg gcggctcccc ggccacccac ctgcacgccc
     2521 ggcaccgcgc ggtgatgccc gagtggctct ccctctacta ccgcgagccc ctggagctca
     2581 cccacggcga gggccgccac gtctgggacg cccgcggccg ccgctatctc gacttcttcg
     2641 gcggcatcct caccacgatg accgcccacg ccctgcccga ggtcaccaag gccgtgtccg
     2701 agcaggccgg gcgcatcctg cacacctcca ccctctacct cgaccggcac atggtcgagc
     2761 tcgccgagcg catcgccgcc ctctccggca tccccgacgc ccgcgtcttc ttcaccacct
     2821 ccggcaccga ggccaacgac gccgccctcc tgctggccac ctcctaccgc cgctccaacc
     2881 agatcctggc gatgcgcaac agctaccacg ggcgctcctt ctccgccgtg ggcatcaccg
     2941 gcaactcctc ctggtcgccc accagcctct cgccgctcca gacgctctac gtccacggcg
     3001 gagtgcgcac ctccggcccc tacgcccacc tgtccgacgc cgacttcacc gccgcctgcg
     3061 tcgccgacct cacggacatg ctcggccaga cccacggccg ggtggccgcc ctgatcgccg
     3121 aaccggtcca gggcgtcggg ggattcacct ccccgcccga cggcctctac gccgccttcc
     3181 gcgaggtcct cgccgagcgc ggcatcctct ggatcaccga cgaggtgcag acaggctggg
     3241 gccgcaccgg cgaccacttc tggggctggc aggcccacgc cgagcacggc ccgcccgacc
     3301 tcctcacctt cgccaagggc atcggcaacg gcatgtccgt cggcggcgtc gtcgcccgcg
     3361 ccgaggtcat gaactgcctc gacgccaact ccatctccac cttcggcggc agccccgtca
     3421 ccatggccgc cggcctcgcc aacctcaccc acctcctgga acacgacctc cagggcaacg
     3481 cccgccgggt cggcggcctg ctcatcgagc ggctccgcgc cgtcaccgca ggcttccccg
     3541 ccgtccgtga ggtgcgcggc cgcggcctga tgatcggcat cgagctggtc gagcacgacg
     3601 gatcgccctc gccggaagcg gcatccctcg tcctcgaact ggccagggag gaaggcctcc
     3661 tgatcggcaa gggcggccgc gaggccaacg tcctgcgcat cgcgccgccg ctgtccctca
     3721 ccatcaccga ggcggaggag ggcgcagccg cccttgaaac ggtgctgcgc caagtgcagt
     3781 tcaccatcgc cggaaaggaa cggccatgac cacgacggcc atccgtggcg gcctcgtcat
     3841 caccgccgcc gaagagacca gcgccgacgt gctcgtcgag gacggcaagg tcgcggccct
     3901 cgccgcgtcc ggcagcgcct tcgcccaagg ctggcacgcc gaccgcaccc tggacgccac
     3961 ggggaagtac gtcatccccg gcggcgtcga cgcccacacg cacctcgacc tgcccttcgg
     4021 cggcaccgcc tcctccgacg acttcgagac cggcacccgg gccgccgcct ggggcggcac
     4081 caccaccatc gtcgacttcg ccgtccagag ccgcggccag gccctgcgcg agggcctcga
     4141 ccgctggcac gccaaggccg ccggccgctg cgccgtcgac tacgccttcc acatgatcct
     4201 ctccgacgtg aacgagagct ccctgaagga gatggacctc ctcatcgccg aaggggtcac
     4261 ctccttcaag ctcttcatgg cctaccccgg cgtcttctac agcgacgacg ggcagatcct
     4321 gcgcgccatg cagcgcgccg ccggcaacgg cgggctgatc atgatgcacg ccgagaacgg
     4381 catcgccatc gacgtcctcg tcgaacaggc cctcgccgcc gggcgcaccg acccccgcta
     4441 ccacggcgag gtccgcaagg cgctgctgga ggccgaggcc acccacaggg ccattcagct
     4501 cgcccgcgtc gccggcagcc ccctgtacgt cgtgcacgtg tcggccgagg aggccgtcgc
     4561 cgagctcgcc caggcgcgcg acaagggact gcccgtcttc ggcgagacct gcccgcagta
     4621 cctcttcctg tccactgaca acctcgccga gcccggcttc gaaggcgcga agtacgtctg
     4681 ctccaccccg ctgcgccccc gcgagcacca ggccgtcctc tggcgcggcc tgcgcaccga
     4741 cgacctccag gtcgtctcga ccgaccactg cccgttctgc ttctccggcc agaaggagct
     4801 cggccgcggc gacttctcga agatccccaa cggcctgccc ggcatcgaga accgcatgga
     4861 cctcctccac caggccgtgg tcgacggcca catcacccgc cgccgctgga tcgagatcgc
     4921 ctgcgccgcc cccgctcgga tgttcggcct cgccccccac aagggcacca tcacccccgg
     4981 cggcgacgcc gacatcgtca tctacgaccc gcacgccgag cagaccctct cggccgccac
     5041 ccaccacatg aacgtcgact actccgccta cgagggcaag cgcgtcaccg gacaggtcga
     5101 gaccgtcctc tcccgcggcg aaaccgtcat cgagcagcgg aagttcaccg gacgcgccgg
     5161 ccacggccgc tacgtccccc gcgccacctg ccagtacctg acgtaagacg ccacgacgca
     5221 ccacgtatga cgttaaggag cacctccgtg gacttcggcc tcgtcctgca gaccgacccg
     5281 cccgccaccg ccgtcgtcga cctgatgcgc cgcgccgagc gctcaggctt ccgctacggc
     5341 tggacgttcg actcctccgt gctgtggcag gagccgttcg tcatctacag ccgcatcctg
     5401 gagcacaccg agcggctcgt cgtggggccg atggtcacca acccctccac ccgcaccccc
     5461 gaggtcaccg cctccacctt cgccaccctc aacgacatgt acggcaaccg cacggtgtgc
     5521 ggcatcggcc gcggggactc cgcgatgcgg gtggccggcc gcaagcccaa caccctcgcc
     5581 tccctgcggg agtccatccg cgtcatccgc gacctcgccg agggccgcga ggccgacgtc
     5641 ggcggcacgg cgctgaagat cccctggatc cgggacggca ggctgcccgt gtggatggcc
     5701 gcctacggcc cgaaggccct cgccctcgcc ggccaggagg ccgacggctt catcctgcag
     5761 ctcgccgacc ccttcctcac cgaatggatg atcaagcacg tgcgggaggc cgccgccgag
     5821 gccggccggg acccggccgc cgtcagcatc tgcgtcgccg cccccgccta cgtcggcgac
     5881 gacctcgccc acgcccgcga gcagtgccgc tggttcggcg gcatggtcgg caaccacgtg
     5941 gccgacctgg tcgagcgcta cggcgagcac tccggcctgg tgcccgaggc cctcaccgcc
     6001 tacatcaagc agcgccacgg ctacgactac agccaccacg gccgggcggg aaacccctcc
     6061 acggacttcg tgcccgacga gatcgtggac cgcttctgcc tcctgggccc cgtggaggcc
     6121 caccgcgaac ggctggagca cctgcgcgag ctcggagtgg accagttcgc ggtctacgcc
     6181 atgcacgacg cgaaggaggc gacgatcgac gcgtacggcg agcacctgat ccccgcgctg
     6241 agctgagcgg agcggagccg gggcgggccc ggccgccgga ccccggcgca cgtgcccgcc
     6301 cgccgcccac cgctcgtcgg ccaccgcccg ccctacggca cgcgcgccgt ccactccgcg
     6361 gaggagaact tcgtcgcggc cagttcctcc gcccgcgcca tctcctcggg ggtgaccgag
     6421 cccgccgtga gcccgtagcg gccccggaag gactcgatca tcttctcgat gacgccggcg
     6481 cgcggcagcc cggtctggcg gcgcaggggg tcgacgcgct tcttcgcgct cttcgtgccc
     6541 ttgtccgaca gcttctcctt gccgatgcgc agcacgtcca gcatcttgtc cgcgtcgatg
     6601 tcgtacgcca tcgtcacgtg gtgcagcacc gcgcccgcgc tgcccaccag ccgcttctgc
     6661 gccgcgcccg cgatcttccc cgactcggtg gcgatgtcgt tgagcggctg gtaccaggcc
     6721 ttgaccccca tgccctccag cgcgcccagc acccagtcgt ccaggtaggc gtagctgtcg
     6781 gcgaaggaca ggccctgcac cagggcgtcc ggcacgcaca gcgagtaagt gatggtgttg
     6841 cccggctcga tgaaggtcgt agcgacagta cactacgacg atcatcgagc ccggttcagc
     6901 ggaggctcgg cgcgggccta gacacccact cacctgcgga aacgtcgccg atccgctctt
     6961 cgtcctcgtt gctgagggcc tggaggaggg ccatcgaggc aggggtcccg tcgtccgcga
     7021 ggagccgcac cacgtgctcg aactcctgcg gagtgaacct cgccgccagt tccgaggcgg
     7081 ctccctcgca tggcgtctgt gcggcctcgg cggctcgcca agccgctacg ttcgcgagcg
     7141 tattcgctaa gaagcgagtc gcgttgtccg gacgctcgat cggcgtgggg ggagggcgat
     7201 cccccacgcg tcggtactca cccaattcca tgatcgagac cctaatggcc aagatcggga
     7261 ttggctgtga tctatggaac gcgggcggtc cactcctggg agctgaactt ggactgcgcc
     7321 agttcttgcg cacggctcag ctcctgctcg gtcacctcgc caaccgagca gccgtagcgg
     7381 tcgcggaagg aggcgaccat gcggtcaatg acctcggtcc gaggaagacc tgtctgccgg
     7441 cggagcgggt cgacgcgctt cttggcgctc ttggttccct tgtcggacag cttttcccgg
     7501 ccgatgcgca gaacctcaag cattgtgtcc gcgtcgatgt cgtaggccat ggtcacgtgg
     7561 tgcaggaccg cgccgttctc gccgaccatt cgcttttgcg cggccccggc gatcttcccg
     7621 gactcggtgg cgatgtcgtt gaggggctgg taccaggctt tgatgcccat gtccccaagg
     7681 gcggcgagca cccagtcatc gaggtaggca tagctgtccg cgaaggacag cccttgcacg
     7741 agggagtccg gtacatagag cgagtaggtg atcgtacttt ggggttctac gaacatagcc
     7801 ccgccgccgc tgatgcgccg gacgaccgtc atgccatgac gcgcggcgga ttccatatcc
     7861 acttcgttgc gcaacgactg gaaactaccg atgatcacgg ccggcgattc ccattcccac
     7921 acgcgcagcg tcggcggccg ccgcccggcc gcgacctcgg cggtcagcac ctcgtccagc
     7981 gccatgtgca gcgcggggga ctgggggccc tcgtggatga gctgccagtc gtagtcgtgc
     8041 cagtcggtgg cattggccag ggcgcggcgg acggcgacgc cgacagcctc ggaggtcaga
     8101 ccgaacatga cggtgccctc gggcagcgcc gcgtcgatac gggcggcgag ctcttgcgcc
     8161 ggcaggtcgg cgttggcccc ctccagcgcg cgattgatgt cgaacagcgc ctcgtcgggc
     8221 tccaggaaga agtcacccgc gacccggacg tcacggaggg ccccgtcgcg cacctcgacg
     8281 tccacgacga ccagcttgcc gcccggaacc ttgtactcgc cgtgcaccgt gcaccttcca
     8341 gaaacgtgcc tctgagccgt tctcagcggc ggatacagcc accgtacgtg ttgggccgag
     8401 gtgcccttgg ccggagcgtc ccggacgtgg ccacgatccg cggcaatggc cgacctaccg
     8461 cctgaagcgc cagaggagcc ggtcagagcg tgccggtgcc cgctggccac cggcccagcc
     8521 agaaggcagc agtggagggc tgttttccgc ccagggtgga gccgtcgtgg ggcagcagct
     8581 cggtgggggc taggtagccg tccccgggat ccaggcggat gcgcaggcat tgcagcggcc
     8641 gcccctgggt gacatagcgc ctcacgtcgt ccgtgtgcgg gtagtggtgt tccgggtcgg
     8701 gatgaacgag tcggtagatc tcttcgatgt cccggtcacc gaggaggaag tagcggacgc
     8761 cgggtcctag gttcaggcag agcctgcgtc ggccgtcgcc ccgggccccg taggggagac
     8821 ggtcccagtt gtcgacgtgg aggccgaggc gtcgcccggt ggcggggtct tcagtcgtgg
     8881 tgcgcgcgtc tccaggattc gtgacgcagc ccaggaaatc ggccggacag cggtccgcga
     8941 acggatagag gtcggcggcg gtcgcgtgga tgtccgatac ctcttccgcc cgaatgaccg
     9001 gcaggggctc gcgcaccaat tcgatcagcg tgccgtcggg ggtgccgggc tcggcctcga
     9061 accattgggc ttccctcatg ttcagcggcc gccagtcacc ggccggcacg actgccccat
     9121 cgtcgtattc cgcttcatcg tggctcaacc ggacggaacc gatctcacac cgctcacgga
     9181 ggcttccgca ctggccgaac gccaagctca ctgccatcgt cgtccctctc gtcctaggca
     9241 ggggtcattc gtcgtcgagg tcttcgccgt aggtgacctc cagctcggcg gccagcgcat
     9301 cggccagttg ggcgacctgg gcccggtcaa taaggacctt cttgagcgcg gccgttccgc
     9361 gtagcgtgct caggtcattg cctcgaaggt cgcagtcgcg gtacttgccg ccctcgaact
     9421 cggcgagccg caagtcacac gcttcgatgg ccactgagcc gaggtcacag gcccggacgg
     9481 ttgtctcccg gagggtgcac ttcgagaaga tcaccgggcc ggtggcgcgg actcggtcga
     9541 gggtggcgta gtcgaacttg cagttttcga agaggacgtt gtccagggcc acgtcctcca
     9601 ggagtgcccc catcagcttg cagttgctga acgtaacgcg ggacagcttg ccgtccgacc
     9661 atttcagaga ggagaggtcg cagtccgaga actgcaccga gtcggcccgc acctcgtgga
     9721 accgggcacg ctgggtcctc acccgctgga tgcggccgtc cagcaggtgt gtgccgacga
     9781 ggtcgagttc acggaggtcc atgtcggcgt actggaactc tgcgactcgg ccccggccgc
     9841 tttcgagtga ctggacgttc gacaggtaca ggcccggctc atccagggcg ggcagggtca
     9901 cgctcacacg gcgtaccttg cgcgattcca tgcgctcttc cttcacggtg tcagccggtg
     9961 gcacgcccgc gtccgcgcag gcgtgccagg ggggagccgt ctacttcttc ttgttccagt
    10021 tgtcccaggt cggctggttg ttgaaggtca ccggaggctc cttcgcccag ttgtcccagg
    10081 tgggtcggtt gtcgaacttg gcgtggatcg gtccaccctg cgggcggccg aacgcggcga
    10141 tcagctcacg caccacgggc gcgtcggtgg cagtgagctg ctccagtaag gtcatgcgat
    10201 ctgctccttc ttcgcggtgg tggacagggc cattaccagg gcctgccggg aaacacggca
    10261 gtagttcgtc tctgtggtgg ccaggctccc gttctcgaag tagcggttgc cggcctgggc
    10321 accccggcag aagtcgaaga actcgcattc ggcctggcag cgctccaggc cggtcaggaa
    10381 ctcgcggacg tagcgcaggt ggggggcttc cctcagcatg tgcgcgatgg ttttctcccg
    10441 tacgttcccg gcaaggaagt cggcgtaagc ggagtcgctg gtgtcggcca gttccggcga
    10501 taacaacacg acgtcgccgt tccaggtcac ggtggggatg gggtcaagga gacggttgtc
    10561 ccagtcatcc ttctgcccgc tccgggcaag gctgaggtac tcggagatcc gctccagctc
    10621 gcgtatcacc gggccgcggt gactgcgtga ccacgccagg acccgccgcc agaactcctc
    10681 ggcctgatcg cgggtgggcg gccggcgctc ggtattgacg ccctcggtct cctcgatgtt
    10741 gaagcccact gagtggcagc ccagcgtggc aacgaagtcc agcagctctt ccgggtggcc
    10801 gatgccctcc cgccccacca ccgcgatcac cgagaacggg ataccgcgct cccgcagaag
    10861 accaacgccc cgcatgatcc gttcgaaggc aggccggccc cggaggtcta cgcgctgggt
    10921 attcagggca gccgggccgt cgatgctcac gccaacccgg aactcgaact cttccagcag
    10981 gtcgcaccaa gcgggtgtga ccagggtggc gttggtctgg acgtagtggt gcatccggcc
    11041 gtcctggcgc agggtctcga agggggcgag cagagcggag aacttctccg tccccagggt
    11101 cagaggctcc ccgccgtgcc agaccagacc caacgggtga ccgatgctgg cgaggccggc
    11161 aagggactca gccacggctg cggccgtagc gggcaacatg tcgttcttca agcccttgtc
    11221 tcgcaggtag cagtagaagc accccatgtt gcagaaactc gtgggctgga ccacgacggt
    11281 ctgtggcttc cgcgcgaacc accggccgta ccggcggtgc ggccgactac cgcagcgttg
    11341 tgtcatagaa cccctcctct tccgcggcct catcgtcgcc ctggactgcc ggccgtctcc
    11401 gtcaggaacc cgagtccgtt cttcttcagg aagccgtggc agcgttgacg gcccgcacga
    11461 ccggggtggg gggccacggt ggcttgcgga cgaccgtcac gccgtgctcg tcgcaccggt
    11521 acacacccgc gcgaagcggt tcgatgctgt gcccgccacg cgggcacagc atggcgtcag
    11581 gaccgccccg gggtcggtac cgggtcacca ctggaccgtc cggtgcatgc tcgaccagtg
    11641 ggccacccgg tgccgagcgg accgtgtctc agccgccacg tcaccgctcc tgatggcctt
    11701 ggccaggtcg gcatccagca agcggcaggt gcggcaggac ggccccggcg cgtcggccgg
    11761 ggcaacgtag tcgtggcccg gcccggaggc gtggggagtg gtgaccagat atcggtaggc
    11821 cacagagagg tccgggcgct ctgccttcat gctcaccgcc gctccccctg ggtggcgggc
    11881 tgcacgtaag ccatggcccg gcagtaggtc cagaacgcgg tgtggtcggg ttggcggccg
    11941 gtgtggcgca tgcatgcctg gtgcatggcc gcgtcgtcac tccgctggac ggtccattcg
    12001 caggcgagac actgggcgcc gtaggtgatg gtgtcggagt gcacgacgat gcggtgcagg
    12061 acgtatcgcc agatggcccg caagccacgg gcgtccttga cgatctcgcg ggttttcaca
    12121 tgggcggtgg tgctcacggt gcacccgctt cccgccgagc agggcggacg ggctggcatg
    12181 gctgccgggg cgtgggcact ttgacgaccc cgcccttccc gaccacgaac gcccggtgcg
    12241 agttcgggcc gccgtcggcc gcgctgtaat gcgcgggatg cggtctcacc gtcggtcggt
    12301 tgggatcact caccgtatgc tcttcgcgct ccgcttcggg agggggtaag tgatctgccg
    12361 ggccacttcg agtggggcgt tcatggtctt gggcggatgg tccttgaaga tcagaacccg
    12421 gccgtgctcc ggctggcgca tgtccatcac gcgtcgccac gccccactga ggagaaccca
    12481 atccccctct ttgactccgt ccggtggaac acggaccttc ttcattccct agggaaccgg
    12541 aatctcctcc gtcaccggtc gcctcctcct cgcatctctc gatctcgtcc agggcagcgc
    12601 gccactcgaa cccgcccccg ggcgggagga gccagacaca accggacggc gaatcgctgg
    12661 agaaacggac ggggtcaccg atcccgtgaa cgatcccaac ccgaccccgc cccgtatcga
    12721 gaacacacac gcccaaggcg acccagtcgg gcagtacagg ggggctgttc ggcagcgtcg
    12781 tcatgcgctt gaacgtagga ggacgaggcg ctcaacctca acgatcttct acagaattgc
    12841 acgcgggtta ctagagggcg tcaatcgcac tggtgatcag ggcacgagcc tgccgaccgt
    12901 acacggctag ctcgcccagg tccgtgaacg cctgtgcgta ctgctcgacc tcaccgggcg
    12961 cccggatgtt gacggcggcc gtcaacagct ctacctgcac ctgctcctgg tcgaagatca
    13021 tgaacgtctc aagcgtccac atactgcgcg atgccgcgaa agggatcacg ccaagggaca
    13081 cggatgggag cgacatgacc gtaagaaggt agccgagttg gcccgccatc gtctccgcgt
    13141 ccccgatccg gtagcggaga acggactcct ccacgaggag cgcgaaacgg tgctcaccct
    13201 tgtggatcac cttggaccgt gcgactcggg cggcggcagc ttcggccgag tcgtcggggg
    13261 tgccctgcgc cctgctgatg agcgcgaaca gggccgtggc gtaggcttcg gtctggagta
    13321 gcccggggat gacgttggag cagtagacgc gaaactgttg ggtgctctca tacagcggaa
    13381 cgcgcgactc ttgcagtcgc cgactaccgg ttcgctgaag cctcttccac tgcacataca
    13441 tggagtcggc ggagcggttc gccgcgatga gatcgtctgc ttgatcgtcc gcaccgcaaa
    13501 cccggcacca tgtcctgacg tcctcgtccg atggcggcgt tctggcgttc tcaatgcgtg
    13561 acgacttgga ggcgtgccag ccagcacgcg tagccagctc atgccccgta agccccgcgt
    13621 ccttcctgat atcgcgtagg cggccggcga tggcttcgcg tgccgcctgg gcactggaag
    13681 aaggcgagat gggcatgggc tggctatcgg acgggcgggt cagatctggt actgctcgtg
    13741 cgggatcccg cggtcccaga cggcttcgaa cgcggtagcg cacagcttga tgacgtccgg
    13801 gtcttcggag acctgcggtt cagtgtctac gccgtcgccg ctgaagtggt tgaacctcac
    13861 gatccgttcg tcgatcaacc agaagtcgac tccggggagg gcgaggtcga acgtctgacg
    13921 tcgaggcagc caccgcacca actcaccagc cgcgacgttg gtgaacgtag agctgtgctc
    13981 gaagcggatg tagtcggtca ccggttcgga aacaatccgg gcccgacgca tgactacgcc
    14041 tcgctggacg gtctcttgga ccaggtccag ccaggggcgc caccatgagt cacggtcctc
    14101 gacgtccaga cggtgtccgg ccttccaagc ctcgaactct ccgttctcct gttcgaccgc
    14161 gtacacgtcg cgcatctcaa ggtgaatcgc cgagtgcctc gcgctggtca gcagctccga
    14221 gaagctgggc acgtcgttct gcctcatcac acgccttcct gatgatcggc accatgcgaa
    14281 ccggtacccg gactacggcc tcatggtcag ggcgggggct gttcgcccgg cactcctctt
    14341 cggtctcttc gtccggcttc cacccctgga acaggaggtc ggcgttcgcc ttgtccaccc
    14401 atgcagcggg acagttaccg tcgttggtgc tgggatcgat gccaatgaac tctagtgcca
    14461 ctgtgacctc cataccgagg gcgttgcact gtcgtgcacg acaatcgtca atctatgcaa
    14521 ggcgtgtcaa ggcggctgca ccttcacgcc agttgccttc gcgggttgca cagttgagcg
    14581 gccatgaacg ccgaaacgcc cccacgccgg cggggtggcc ggggcggggg cgtggtctca
    14641 gtgggccggt gtggcttgcc agatcgtaag agccagcgtg accaggctga taaccgctgc
    14701 cagactggcg aggggccagc gattgcgttc aagggcgtcg agtcgcttgt cgtgatcggc
    14761 tagctgtcgg tcgctctggt cgctgcgctg gacgaggagg gccaaggcgc cgtcgacgcg
    14821 ggcgaatccc gcctccatgg ttcctcggag gcgctcgagt tccaacgcga cggccgccgc
    14881 gtcggccggg gcgggaccgg tcacgcactg ccctcgcggt cgtcggtggg cagagtggcg
    14941 cgcgggtggg tgcgaagcca ggccggcatc agggactgca cgccgggaat ggccatgatc
    15001 cgggtcaggc cggcggcgac agcgagcgcg ccggccgccc acgggagagt ggagaggatg
    15061 ccggacgcgt cgatgatcac aggcaggagg gcggcgaggg tgatcgtggt ctgaacggtt
    15121 gtacggatgg tgcgccgggt ggcgtcggtc aagtgggcgc ctttcatcgg gctccggtcc
    15181 tgggcgctcg agtgcgcctt ggcacggagg gacaggatca ggtttgggag ggggtggcgg
    15241 tgccggcggt tacttgctga ctcgcggaac cttcagtgcg tcccactgcc ggggcccggg
    15301 ccagccgtcg cagaattcgg gcgagttgcc gagcttgcgc tgccaacggc ggaacgactc
    15361 gcggtcggcg tcgctccagt cggggccggg gccctgctgg taggcgccgc agccttcggc
    15421 caccagacgg cggcccatgg cggtgatgat cggcgaggtg gggccgctct tgaaccatgc
    15481 ctcgcccggg aacggctcga agccgccccc ggtgacggcg gccccgccgc tgccagccgt
    15541 ggtccggccg gcggggatgt cgtgttcgtc ggcctggtgg gcgaagaaga ccacgccctt
    15601 ctgcccctgg cggagggggt cggccaggac ggtgccttcg gggtaggtgg ggatgccgta
    15661 cccgtatatt cggtcgctct tacgggggcg ggttcgcaga tagaccccgt cgccctcgga
    15721 ggcacccgtg tcgttggtgt tgccttcaac ggtcgtgatc tcgtcgtccg tgtaggcgat
    15781 gcagatgccg acatgttcgc caccgccgtc gccgtagtag acgacgccgc cgatcacggg
    15841 gtagtcgctc cactggtccc gctgcttgaa ccattcgacg ccggcggagc aggaggcggt
    15901 gacgggagcg aggctcttcg cccctgcctg ctggaagcac cagctcacga aggtgtggca
    15961 ccacgcctgg ccctgcgccc attcgaggcc ggggaccgcg ggtgcgtact tttcctggtt
    16021 gttccagtgg ccgtctgagt tgcggccttc gtggtagccg acttcccggc gggcgatgtt
    16081 gatcaggtgg cgtgcgacgg gcatggagtc cttgtcttcg tcgttctggt cgggcggggg
    16141 tttgccgctg ttggcggcct cctcggccgc cttgcgtgcg gcttcctggg cgtaccgcga
    16201 tgcctcctgc acggccttgg cggctgcttc gtaggcggcc ttggagatct cgtcccagcc
    16261 gccgttgcgc gggggcggcg gggtggtgtc gacggcgaaa cgaatgctgt cgaggtagat
    16321 ccacctcacg ggtgacagca ccatcgcttg gagctggccc gggtacgggt cgctgttcga
    16381 cgtgacgtcc acacggatgg agttgtgggt gttgtcgttg cgggaggtgg cacagatgaa
    16441 cgagcgcatg tagtgcggtt gggcggccgg cggcaaggtg gccagcagcc agctgtcggc
    16501 gacgttgaag tcccggccgt ccttgcgctc caccgagccg cacagctcca ccgtgccgtt
    16561 cacgatgcgc cagctcggat tgccgccgtg ggccttcacg tcgtggggca gcggcaacgg
    16621 gttccacggg cccggggaca gcggaaccca cgccgactcg gtgcgcagtt cgaggcgctg
    16681 ttcgtcctgg aggtaggcga gcttgccggg taccggcgtc tcgagtgccg ctaggcgggc
    16741 ccccgcgttc gcgtacaccg cctgcgtcag ggtgaacacg cgctcgtcga tgacgtcggc
    16801 cggccggatg gcgccggtct gcggggcgac ggtgatgcgc acgaggggga cgtccacgat
    16861 gccgtcttgt ccctgggcga gggtgggcgg caggggcttg gtggccggtg tgccggtcag
    16921 gtaggcgatg gcgatgcgtt gggcggtgcg gtccaggcgc acggtgatgc ggtcggtccg
    16981 tggggtggtg cccgtgttcg ggctgaccac gatgttctgt ggggcgtcgg cgtggtagtg
    17041 gtggccttgg acggtggcgt ggccgggggc gagggtgatg gtcatgtcct gcccggtggt
    17101 ggtggcgccg agcgggtcgg gctcgccggt gcggggggcg cggacgccgt cggtctgcca
    17161 catcgaggtc atgtgggacc actgggtgga ggtgaccgtg gtgccggccc cggagtcgaa
    17221 gggatagaag tactcggcca agccggggcc tccggggtca gtgtcgggtg ttgagttgat
    17281 gaacggcctg ccacaggcgc cggacctgcc cgtacagggc gggggtcttg gtggcgttcg
    17341 cggtgcccac ggtggcctgc accgttgttg tctcggcgct gtcgctcacg tgtacttcgc
    17401 gcaccgggta ggccagatcc acgccgccgg cggtggtgac ggtgacggtg tcgccgacct
    17461 ggtagtgacg gccgtaggtc atctgtgggg tgtcgatcgg cgacagcgac agctcggcct
    17521 gttgcccgct ttgctccagc gcgcgggcgg cggcctcggc gagtgccgtg tactgcgggt
    17581 cgctcgcgtc gaggcgggcg gggacggggg tatcgcgctg gtccacgaag gtctcggccg
    17641 tgcggtgcca gtcccgttcg gcgtcggggg tggtccactg ccagaagaag cggtccgccc
    17701 cttggccttg cgcggccacg acggctcggg tggccttcgg cgcggtcagc tcgtaggagt
    17761 aggcggagag gttgccgaac tgcggggaga gccggacctc tcgggagagg tcgcggacag
    17821 gtgcgatggc cagcgcgagg cgcgcggtgg tggggtcggg ctggacgatg cggaccgaca
    17881 ggccggcgcc cgtggcgagc gtctggacgg cggacaggac ggtgtcgaag cgcagccgcg
    17941 ccgtggcggc cggaccggtt gccgcgggcg tgccgggcgg tggcgtggtg tcgagtccgg
    18001 cgacgcgccg gcccggcaag gcccggccgc cgagattggc ggcgaccagc tcgcggacga
    18061 tgtcggcggc cgggccctgc cggacccagt agtccacgct gtagcggccg ttaccgttgt
    18121 cgggcgcgcg ggaggggtcg gggaaggcga ggcggtcacc gagtggggcg ttgtcgcagg
    18181 tgccgctgaa ggtgagggtg ccaccggtgc cggtgctgga cgaccagtca tgccggatct
    18241 tggtaacggg cccgctcagc agcggctccg ccgcagcctc cccggtgccc ccgccggccg
    18301 ttgtctccgg ccagatgatc acgccttgcc cggtggtcag cagccgcgcc tgggggtggg
    18361 tggccggcag ggtcaggctc caggtgccga cgtcgaggtg acggacgatg acgtccaagc
    18421 tggtgtaggc atcgacctgc ccgacgcgcc ggagggcggc gtcgcggaca tcgacgcggt
    18481 agcgccgcag gggaatcagg ctccgtagtg tcgggactgg taggtcaagg tcaccgcgga
    18541 ccggtcatca gcgccggcgg ccgtcaccgc gacggtgttc gtcccgggga ccagcggcca
    18601 cagggccgcg ccgccggtga cgtggggcca caggttctcg ccctgccccc cgccgggcgc
    18661 ctcgcggtag acggccttga tgccggggcg ggtgtcgatg acgacgactt caccggcggc
    18721 caccgcgtag ttcagggcca gggacttgcc cgtggtggtg ttggacaacc gcagcggcac
    18781 ggcgggttgc ccggcgtcct ggtgccccag ggggccggtg atccgccaga ccggccacgc
    18841 ctcggtgtcg gacgtgacgc tgatgggcac cccgtcctcc ccgatcacgc tcgctccgat
    18901 ccgcaagggg aagaacgccg cctcggtcgt gtcgtcgcct gcggggccgg aggcggtggc
    18961 ggggagacgt gagaggaagt gcggggtgcc gccgtgcacc cggaaggcgg ccgtgcgcag
    19021 gggcccggcc cagtagggat cgggggcgac gagctgaagg ccgtaccggg tgtaggtcag
    19081 cccggcgttg tcgctgctct cgtcgccttc caggccgccg aggtactgca cgccgatggt
    19141 gcgggcggac ccgtcggcct cggccacgcg cagcgtcccc ggcccggcca tgacggcggt
    19201 gatcagccgt cgtcgcaggg ccagcagttc gggccgtgtc ggcgcccaca gcagaagcgg
    19261 caggttgatc cggcgcgtgg cggccctggt cttgacgacc tggccgccgt ccaggccggc
    19321 gtactcggag acgctggcct gccagggcgg ggcgtccatc ccggtggggc cgggaaggat
    19381 ggcgatgcac gcgcccacct gcgcgaggct ggccgtcagc aggaactctg tcccgtccgc
    19441 ggtggtcagg gtgaccgctg gcggttgatc cggtgcggac gtgccgtcgg tcgcgtccct
    19501 gtcggtccag gcgccggaat cggcgacgac ggccgacggg gaattcagct ccgcaagcgc
    19561 acgcacagcc ccaccccctc tttgttccgg atggctccgc gccacgaagg gggcggtggg
    19621 ttaggcgtac aaggcgtcag cgaagcgaag ggcgctgacg atctgctgtt ccgtgggaat
    19681 gccgggaacg gcatgcaggt ggactaccgg gccgcttccg ccgctaccac ccttcggggg
    19741 cgccgcgttg aggccctggg agttggcaat catgtcccac tgcgtcggcg tgaataccgg
    19801 ctccggcgtg cccagaccgt tgtagacgag ggacaagccc gggggcagat atccacccga
    19861 gtcgtaaccg cccggtctgt tgagagcggc cagtgaaccg tacctgtgca cggcatagtt
    19921 gaggccggag tagatgttgg ccagcgggtt tgttgaggtt ccgtagagga acggccccac
    19981 gttccggagc ggaccggcat aggcgtcaaa ggtcgggcca atgacctgca tgaggccgac
    20041 acttggtgtg ccgtcctgcc aattaacgtc ccaggtattg acgatgttcg ggttgccgcc
    20101 ggactcgtca ttcattcgcc gaagaacggt gtccagccac gaggcgggtt gcccgagcat
    20161 ggaaagggcc tggagaacct gcggcgtcca ccgagtgacg ccactgccgc cgacgtcacc
    20221 actgctgcca ccggccgaga agtagccgcc gacaaagtca acgacggtgt ccttcagacc
    20281 ctttaccggt gcagtgaaaa cgtgccggat catctgcgac cacttggcgg ggttcatgtc
    20341 gtcgaggtcg ccgaggaccg acgccaagag cttgtccatg gccttgccgg ggtgggccat
    20401 gatgtcggcc gcaccctgga ccccgcgcca cgcggacttg gccgtgtcgc tggtccagtc
    20461 ccagaccttg tcggccgcgc ccttgcccca ctcggccgcg gtgccgatga tcccgccctt
    20521 ggcgagcatc tgcgcgccgg cagcctggag cagacccagg gcccgaggcc ggtatttcgg
    20581 atcggtcggg atgacgtact caggccaccg gggattgccc tcacccacga tcgccgtggg
    20641 ctggttgaat acgcccggcc ggacaggcag cgcgccgccg gaagcgagta gcggaagctt
    20701 gtccatcttc agcttgtcgc cgatgtccgg aatccagccg gtgagcttgt tccagatgtc
    20761 gagtacgccc ttgttccaca cggtgccgat cacgaagttg accggcccct tcgtggcctc
    20821 gcggattccg gaccacgcgg tggcgattcc gtccttcgca tgggaaaagg ccgtggcgat
    20881 cagcccgatg ccgaccttca gggcgtcaaa ggcgggccgg atcgcgtgat cccagcccca
    20941 gacaatgacg tcgcccatag cctgccacgt cggcttgatg acgctgtagt agagccagga
    21001 gacggccggt ccgagcgcgt gcttgaggaa ccagacgaag gcatcgacgg ccggccggat
    21061 cacctcgttc caggccaacg cgatggcggc gccgatgagt tcgaacgtcg gcttgacgat
    21121 gacctggaaa agccagacga tcgccgggcc gaggacgtcc ttgaggaaaa tccagaagag
    21181 ccgcagggcg ggctggacga cgtcgcccca cacggtcgcg atgacgcggc cgatgaactg
    21241 gaacatcggc cagatgatcg cctgggcgaa gtcaacgaca accggcccaa gtgtttgaac
    21301 aataaacgac cagaaggcca aaaaaagggg tttcagggcg ccgttccaga cggcgccggc
    21361 cacaagggct atc
//
