LOCUS       NZ_BMUT01000001        32821 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces hiroshimensis strain JCM 4586 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUT01000001
VERSION     NZ_BMUT01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces hiroshimensis
  ORGANISM  Streptomyces hiroshimensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 1281729)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 90X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650335.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:32:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,830
            CDSs (total)                      :: 6,745
            Genes (coding)                    :: 6,620
            CDSs (with protein)               :: 6,620
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 25 of 125
            Pseudo Genes (incomplete)         :: 107 of 125
            Pseudo Genes (internal stop)      :: 4 of 125
            Pseudo Genes (multiple problems)  :: 11 of 125
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 41328
            Orig. end                         :: 74149
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUT01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32821
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..32821
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32821
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:18821](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..18821
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            1076..1786
                     /locus_tag="IE241_RS00170"
                     /old_locus_tag="GCM10010324_00330"
     CDS             1076..1786
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983915.1"
                     /locus_tag="IE241_RS00170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00330"
                     /product="class III extradiol dioxygenase subunit B-like
                     domain-containing protein"
                     /protein_id="WP_190019486.1"
                     /transl_table=11
                     /translation="MLVAAAVCPCPPLLVPEVAAGAAPELDGLRAACLDALGVLAAARP
                     DRLVVLGPAPQPGRGPHPQGARGSFRGLGVDVDVRLGQGPQAGERELPQSLAVAAWLLE
                     RTRWSDAPVEGLGVGETLEAGRCLEAGRELAGADGRTALLVMGDGSACRTLKAPGYLDE
                     RAADFDAEAARALGAADTTALAALDGGLARELKAAGRAPWQVLAGAGEGAGLKGQLLYD
                     EAPYGVGYFVVAWS"
     gene            complement(2027..2275)
                     /locus_tag="IE241_RS00175"
                     /old_locus_tag="GCM10010324_00340"
     CDS             complement(2027..2275)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642213.1"
                     /locus_tag="IE241_RS00175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00340"
                     /product="antitoxin"
                     /protein_id="WP_190019487.1"
                     /transl_table=11
                     /translation="MGLLDTIKAKLAPAKDKIGDLAQQHGDKIEQGLEKAAKVVDEKTK
                     GKYSSQIHTGTGKAKDAIDRLAEKEGGKGGGTGTPAP"
     misc_feature    2253..2266
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.39"
                     /tool="antismash"
     gene            complement(2307..2546)
                     /locus_tag="IE241_RS00180"
                     /old_locus_tag="GCM10010324_00350"
     CDS             complement(2307..2546)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481492.1"
                     /locus_tag="IE241_RS00180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00350"
                     /product="gliding motility protein"
                     /protein_id="WP_190019488.1"
                     /transl_table=11
                     /translation="MGVFSRFRRKSSEASTEEAATATLTAESADATETGAEATEPEESD
                     EAEAEAQAAEGVEIPKQQSAEKAVDSEAGEGARK"
     gene            2742..3680
                     /gene="miaA"
                     /locus_tag="IE241_RS00185"
                     /old_locus_tag="GCM10010324_00360"
     CDS             2742..3680
                     /EC_number="2.5.1.75"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="miaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IPPT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008404157.1"
                     /locus_tag="IE241_RS00185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00360"
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="WP_190019489.1"
                     /sec_met_domain="IPPT (E-value: 5.5e-85, bitscore: 280.9,
                     seeds: 863, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNAVPAPRVIAVVGPTAAGKSDLGVALARHLGGEVVNADSMQLY
                     RGMDIGTAKLTLEERQGVPHRLLDIWDVTEAASVAEYQRLARAEIDRLLAEGRTPVLVG
                     GSGLYIKGTIDALDFPGTDPAVRARLEEELAEQGPGALHARLAAADPAAARAILPGNGR
                     RIVRALEVIELTGRPFTANLPGEEPVYDALQIGVDVERPELDERITLRVDRMWEAGLVD
                     EVRSLERQGLREGRTASRALGYQQVLAFLAGECTEDEARAETVRATKRFARRQDSWFRK
                     DTRVHWLSGAADRRAELPGLALALLERAVTA"
     gene            3788..4267
                     /locus_tag="IE241_RS00190"
                     /old_locus_tag="GCM10010324_00370"
     CDS             3788..4267
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547385.1"
                     /locus_tag="IE241_RS00190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00370"
                     /product="hypothetical protein"
                     /protein_id="WP_190020367.1"
                     /transl_table=11
                     /translation="MEAGPRDRPQQPPRRGHLPAVAGEEPEALTPDGPEDTEGSVEAGT
                     AAPASFRELRPQRRLRIWQLAPIVVLAAVGSLMFAFPLAFEFGDGGPVVAMLGLLISCC
                     AAGWGVMAARRVGYTWPGMPAPGSGSRPDWRYVASYAVLVAVVVVLAVWRVARLR"
     gene            4342..5232
                     /gene="dapF"
                     /locus_tag="IE241_RS00195"
                     /old_locus_tag="GCM10010324_00380"
     CDS             4342..5232
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602694.1"
                     /locus_tag="IE241_RS00195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00380"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_190019490.1"
                     /transl_table=11
                     /translation="MSTAQIAFLKGHGTENDFVIIPDPDGRIELSPPAVALLCDRRAGI
                     GADGVLRVVRSAAHPEARAMAGEAEWFMDYRNSDGSIAEMCGNGVRVFARYLHHAGLVE
                     AGDLAVATRAGVRQAHIAKGGPDGAPGDVTVGMGRAVLPEGEVTVTVGGRSRPARNVNM
                     GNPHAVTFVDDLADAGNLFTAPGVAPADAYPDGTNVEFVADRGPQHVAMRVHERGSGET
                     RSCGTGACAVMVATARRDGLDPAVTGLPVTYTVDIPGGRLVISEAPDGTVEMTGPAVIV
                     AEGTFESSWLDVARA"
     misc_feature    5358..5373
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.88"
                     /tool="antismash"
     gene            5484..7610
                     /locus_tag="IE241_RS00200"
                     /old_locus_tag="GCM10010324_00390"
     CDS             5484..7610
                     /EC_number="2.7.6.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714594.1"
                     /locus_tag="IE241_RS00200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00390"
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="WP_190019491.1"
                     /transl_table=11
                     /translation="MSTDATHEGAPGRRRGRARLDLRRLGRAALGGSGARGRLPDAIDH
                     VAKVHRAHHPGADLDILRRAYLLAESSHRGQMRKSGEPYITHPLAVTLILAELGAETTT
                     LTASLLHDTVEDTEVTLDQVRGQFGEEVRFLVDGVTKLEKVDYGAAAEPETFRKMLVAT
                     GNDVRVMSIKLADRLHNMRTLGVMRPEKQARIAKVTRDVLIPLAERLGVQALKTELEDL
                     VFAILHPDEYARTRELVREHAAGLATLETTAERMRAVLREADIAADVLVKQRHFVSVHR
                     VRLKRGEVTGSDLGRLLVLVAEDADCYAVLGELHTCFTPFISEFKDFIATPKFNLYQSL
                     HTAVAGPGGEAAQILIRTHQMHKVAEAGVVALGNPYATPETPDATDGERVDPTRPGWLS
                     RLLEWQQATPDPDTFWTSLRDELALDREITVFRADGGTIGLPAGSSCVDAAYAQHGDGG
                     HSCIGARVNGRLATLSTVLRDGDTLQLLMSRDSASGPSPDWLEHARTPAARIAIERWLA
                     SHPAVEAAPPVPLAPGRPCPPPRATAPAARWPVAVTADGADLAAASVRLAGCCTPVPPD
                     EVTGFAVRGGAVTVHRAQCPAVHRMVASGREPVGVRWSSPEGGGARDYRVTLRAESFSR
                     PHLLADLTEAIAAEGAAVISAAVEPPHEQRVRHTYTLQLPDAAQLPELIRAMRRVPGVY
                     DVERAGRPVATAQL"
     gene            7789..9276
                     /locus_tag="IE241_RS00205"
                     /old_locus_tag="GCM10010324_00400"
     CDS             7789..9276
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432250.1"
                     /locus_tag="IE241_RS00205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00400"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_190019492.1"
                     /transl_table=11
                     /translation="MPHSSGKPASVPRRSVRRRAVLAAAVTALLVGAAAPPAANSQGIG
                     DRLFPDLGNPGYDVAAYDINFDYHGNGRPLDAVTTIAARATTGLDRLNLDFSNGTVRSV
                     TVNGLPAKFASAKEDLVVTPSVALPAEGLFTVVVRHTSDPRDGKEGGWIRTKDGLVMAN
                     QADAAHRVFPCNDHPSDKARFTFRVTAPRALTVVANGLPAGRAVRGTNATWAYRSEHPM
                     ATELAQVSIGRSAVVHRTGPHGLPVRDVVPTADRQRVEKWTSKTPEQIAWMEGKAGPFP
                     FENYGLLIADASTGFELETQTLSLFERSLFIRDDIPSWYLESIMVHELAHQWFGDSVSP
                     HSWSDLWLNEGHATWYEALYAEYKGGRTLDARMRAAYEHSDAWRADGGPPALPKAPEPG
                     KRTSIFRPVVYDGGALVLYALRQKIGTAAFDRLEREWTSAYRDADATTEDFTAVASQVS
                     GQDLKEFLQAWLYSPKTPPMPGHADWKAARTAPRKPA"
     gene            9413..10906
                     /gene="hflX"
                     /locus_tag="IE241_RS00210"
                     /old_locus_tag="GCM10010324_00410"
     CDS             9413..10906
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="hflX"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714592.1"
                     /locus_tag="IE241_RS00210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00410"
                     /product="GTPase HflX"
                     /protein_id="WP_190019493.1"
                     /transl_table=11
                     /translation="MTSSSSLPQDRQSLPESLRADALMEEDVAWSHEIDGKRDGEQYDR
                     SERAALRRVAGLSTELEDVTEVEYRQLRLERVVLVGVWTSGTVRDAENSLAELAALAET
                     AGALVLDGVVQRRDKPDPATYIGSGKAQELRDIVLESGADTVVCDGELSPGQLIQLEDV
                     VKVKVVDRTALILDIFAQHAKSREGKAQVSLAQMQYMLPRLRGWGQSLSRQMGGGGSGS
                     SGGGMATRGPGETKIETDRRRIREKMAKMRREIAEMKTGRDVKRQERRRNKVPSVAIAG
                     YTNAGKSSLLNRLTGAGVLVENALFATLDPTVRRAETPSGRVYTLADTVGFVRHLPHHL
                     VEAFRSTMEEVGDSDLILHVVDGSHPVPEEQLAAVREVIRDVGAVDVPEIVVINKADAA
                     DPLVLQRLLRIEKHSIAVSARSGEGIEELLALIDSELPRPAVEIEALVPYTHGSLIARA
                     HADGEVISEEHTPEGTLLKARVHEELAAELQRYVPAARG"
     gene            complement(11050..12240)
                     /locus_tag="IE241_RS00215"
                     /old_locus_tag="GCM10010324_00420"
     CDS             complement(11050..12240)
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105321.1"
                     /locus_tag="IE241_RS00215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00420"
                     /product="serine protease"
                     /protein_id="WP_190019494.1"
                     /transl_table=11
                     /translation="MPSIRRPALAAAALTAALALTATACGPTDDEAAGSDKPSATASQK
                     GDEGLELPKNLPSSLKDLEKWKNGAWKNWDKEQWLREARDFINPIIKGHWKPDTMKDAR
                     PSDKTLATQGAPGTAPGASGDQGVTDPEPRPVQAKSVTVPYHNNAAPVGKVFFDSPEGH
                     MVCSATVVKDPAHPGKSNMVWTAGHCVHAGKKGGWYRNIAFVPSYNDKGLPGAQVNSAP
                     VQDVAPYGVWWADWAQTSAQWITQGAETGGAGAPYDYSVLHVKPEAGSGKSLEETVGNA
                     LTVDFNAPQVKSIQSMGAWGYPAAPPFDGQKMYDCIDRPGRLSLDQNQPTMYRIGCTMT
                     GGSSGGGWFAKGPDGKVALVSNTSIGPANSTWLAGPRLGPEAKGIYDAISRKFANR"
     misc_feature    12338..12354
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.96"
                     /tool="antismash"
     gene            12495..13973
                     /locus_tag="IE241_RS00220"
                     /old_locus_tag="GCM10010324_00430"
     CDS             12495..13973
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (41-375). E-value: 9.6e-92.
                     Score: 299.5. Matches aSDomain:
                     nrpspksdomains_IE241_RS00220_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983928.1"
                     /locus_tag="IE241_RS00220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00430"
                     /product="diaminobutyrate--2-oxoglutarate transaminase
                     family protein"
                     /protein_id="WP_190019495.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.2e-89, bitscore:
                     294.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALTQLPPTEPSAAAYEGILRRQSARESAARTYARSLPIVPVRAR
                     GLTIEGADGRRYLDCLSGAGSLALGHNHPVVLEAIRSVLDSGAPLHVLDLATPVKDAFT
                     DELFATLPRELAESGRIQFCGPAGTDAVEAAFKLVRTATGRDGLLAFTGAYHGMTEGAL
                     AASGAAPSVRVTRLPYPQDYRCPFGVGGESGARLAARWTESLLDDPKSGVRRPAAMIVE
                     PVQGEGGVLPAPEGWLRRMRELTAARSIPLIADEVQTGVGRTGAFWAVEHSGIVPDVMV
                     LSKAIGGSLPLAVIVYRDDLDTWQPGDHAGTFRGNQLAMAAGAATLRHVRENGLAERAA
                     SLGARMLERLRRMAGEYECIGEIRGAGLMIGIEFVAPEGEAGPAPEGHDAGAPDAWHRP
                     GQEPGDNAATGPLPASPVRAAAVQRECLRRGLIVELGGRHSCVVRLLPPLTITDEQTEA
                     VLERLADAVAAVCRPGRRIPAPSTPKEAGAASPA"
     aSDomain        12618..13619
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE241_RS00220_Aminotran_3.1"
                     /evalue="9.60E-92"
                     /label="IE241_RS00220_Aminotran_3.1"
                     /locus_tag="IE241_RS00220"
                     /protein_end="375"
                     /protein_start="41"
                     /score="299.5"
                     /tool="antismash"
                     /translation="VRARGLTIEGADGRRYLDCLSGAGSLALGHNHPVVLEAIRSVLDS
                     GAPLHVLDLATPVKDAFTDELFATLPRELAESGRIQFCGPAGTDAVEAAFKLVRTATGR
                     DGLLAFTGAYHGMTEGALAASGAAPSVRVTRLPYPQDYRCPFGVGGESGARLAARWTES
                     LLDDPKSGVRRPAAMIVEPVQGEGGVLPAPEGWLRRMRELTAARSIPLIADEVQTGVGR
                     TGAFWAVEHSGIVPDVMVLSKAIGGSLPLAVIVYRDDLDTWQPGDHAGTFRGNQLAMAA
                     GAATLRHVRENGLAERAASLGARMLERLRRMAGEYECIGEIRGAGLMIGIEFV"
     gene            14001..15962
                     /locus_tag="IE241_RS00225"
                     /old_locus_tag="GCM10010324_00440"
     CDS             14001..15962
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889956.1"
                     /locus_tag="IE241_RS00225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00440"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_190019496.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.9e-68, bitscore:
                     226.1, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNASTGTGASTAGQDSDPAPERQAVVSAVPRQGGGPCGGIPDTGP
                     PCAPDPLEHPDPAVAADAAAVENLLRCWVRETGVPRPGGPELHLPLAASGTALRVPVAY
                     WSAAGWHRFGPPALADGPGDAPAVDAVTLAALLGREAAHRAARAGCTGTGETAELVGRV
                     ADSARRTAAFLADRRARPADPDAGELFLYAEQSLLLGHPLHPTPKSREGLSDAESHAYS
                     PELRGAFPLHWMAVHRSLLAMDSAWTERGRPVDAPTLAARLAGPELRLPEDTAALPLHP
                     WQAHDVRSRPGVRRLLDAGLLHDLGPLGAPWYATSSVRTVHRPGAPAMLKLSLGLRITN
                     SRRENLRKELHRGVEVHRLLRSGLAEQWRAACPGGLGFDVVRDPAWLAVDTPEGAPLTG
                     LDAVIRHNPFGPGDDAVCLAGLVSPRPWPAAVPQKHPGGPGGRPALRSRLAHIVARLAH
                     RTGRPAGAVSAEWFLRYLEAVVRPVLWLDGEAGVALEAHQQNTLVLLDREGWPAGGRYR
                     DNQGYYFRASRRDALDRRLPGIGAESDTFVSDEVTDERFTYYLGINNVLGLIGAFGAQR
                     LADEQILLAALRRFLQDAASGPAAGRSTLPARLLEAPTLRCKANMLTRLQGLDELVGPV
                     DTQSVYVTIANPLVTSAR"
     gene            16071..16895
                     /locus_tag="IE241_RS00230"
                     /old_locus_tag="GCM10010324_00450"
     CDS             16071..16895
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641006.1"
                     /locus_tag="IE241_RS00230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00450"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190019497.1"
                     /transl_table=11
                     /translation="MPPTDPSEGPGTGPGPDHPGSRTTGLAGPGVADAAPAGAGPPTDN
                     ETTLELQLSEEFIELIDHGAPEPAAITAGRGPAGAIGPGSDLLDSLADWGPADTGAGTF
                     QLVPVRVERDLRLITRWMNDPAVAAFWKLGGPESVTEAHLRAQTGGDGRSIPCLGVLDG
                     VPMSYWEVYRADLDSLARHYPARPHDTGIHLLIGKVADRGRGVGTRLLRTVADLVLDHR
                     PSCARVVAEPDLRNTPCVSAFLSAGFRLTAEIDLPDKRAALVVRDRALRTLL"
     gene            17109..18821
                     /locus_tag="IE241_RS00235"
                     /old_locus_tag="GCM10010324_00460"
     CDS             17109..18821
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092902.1"
                     /locus_tag="IE241_RS00235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00460"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_229898760.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.6e-71, bitscore:
                     236.1, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAKMLGELSYEGVLTPEPDDAAEAPATAYRLSLTDDVTYRFRAR
                     RSAYGHWTVDPDSVTPSQDPLRFLALAHDTVLGLSGDTTGHLARELLATLSADTRLRAS
                     ALSAAHLADLDYAALEGHQTGHPWLIANKGRLGFSASDTDRWAPEARTPRRLPWIAAHR
                     SLAHYRAVPALATPDLLYAEELAPGTRAAFARTVADHGRDPADYLWLPVHPWQWDETVA
                     PLFAPCLADGSIIPLPTDNDLRLPQQSVRTFLNTSRPHARTVKLPLSILNTLVWRGLPT
                     ERTLAAPAVTAWVHSLRDSDDFLRDETRVILLGETASVTVEHPLYDRVPGVPYQYKELL
                     GCIWREPLGPALAPGERARTLAALLHTDPAGRSFTAELVHRSGLAPADWLSRLFAALLP
                     PLLRFLYRYGTVFSPHGENAIVVFDENDVPTRLAVKDFVDDINISAVPLPEHASMPDDV
                     RAVLLTEPPGFLTQFIHSGLFVGVFRYLAPLCEEQLGVPEAAFWSLVRTEIMRHHERFP
                     RMKDRYETFDLLTPRIERLCLNRNRLHLDGYRDRPERPHAAVHGTVPNPLHIP"
     misc_feature    17208..17210
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18865..20844
                     /locus_tag="IE241_RS00240"
                     /old_locus_tag="GCM10010324_00470"
     CDS             18865..20844
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004945335.1"
                     /locus_tag="IE241_RS00240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00470"
                     /product="ATP-dependent DNA helicase"
                     /protein_id="WP_190019498.1"
                     /transl_table=11
                     /translation="MTASSSPSLTDLLHAAVTAVGGTERPGQVTMAEAVAEAVDGDSHL
                     LVQAGTGTGKSLGYLVPALAHGERVVVATATLALQRQLVERDLPRTVDALQPLLRRRPQ
                     FAMLKGRSNYLCLHRLHEGVPQDEEEGLFDPFEAAAPSSKLGKDLLRLRDWADETETGD
                     RDDLTPGVSDRAWSQVSVTSRECLGASKCAYGAECFAEAARERAKLADVVVTNHALLAI
                     DAIEGAPVLPGHEVLIVDEAHELVSRVTGVATGELTPGQVNRAVRRAAKLVDEKAADAL
                     QTAAESFERLMELALPGRLEEIPEDLGYALMALRDAARTVISAIGNTRDKSVQDEDAVR
                     KQALASVENIHAVAERITEGSEYDVVWYERHDRFGASLRVAPLSVSGLLREKLFSERSV
                     VLTSATLKLGGDFNGVAASLGLAPEGTGGAESPEWKGVDVGSPFDYPKQGILYVARHLS
                     QPGREGSRTDMLDELAELVQAAGGRTLGLFSSMRAAQAAAEELRGRLDVPILLQGEETL
                     GELIRNFAADARTCLFGTLSLWQGVDVPGPSCQLVVMDRVPFPRPDDPLMSARQKAVEE
                     AGGNGFMAVAATHAALLMAQGAGRLVRASGDRGVVAVLDPRLATARYGGFLRSSLPDFW
                     YTTDRNQVRRSLAAIDEAAKAEGR"
     gene            complement(20971..21756)
                     /gene="lexA"
                     /locus_tag="IE241_RS00245"
                     /old_locus_tag="GCM10010324_00480"
     CDS             complement(20971..21756)
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965791.1"
                     /locus_tag="IE241_RS00245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00480"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_190019499.1"
                     /transl_table=11
                     /translation="MTTTADSATITAQDRSQNRLDQAHPMNDAAMSTEGQKPARALPGR
                     PPGIRADSSGLTDRQRRVIEVIRDSVQRRGYPPSMREIGQAVGLSSTSSVAHQLMALER
                     KGFLRRDPHRPRAYEVRGSDQPSSQPTDTTGKPAASYVPLVGRIAAGGPILAEESVEDV
                     FPLPRQLVGDGELFVLKVVGDSMVEAAICDGDWVTVRRQPVAENGDIVAAMLDGEATVK
                     RFKREDGHVWLLPHNAAYQPIPGDEATILGKVVAVLRRV"
     misc_feature    complement(21819..21834)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.09"
                     /tool="antismash"
     misc_feature    21820..21833
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.93"
                     /tool="antismash"
     misc_feature    complement(21820..21833)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.77"
                     /tool="antismash"
     misc_feature    21884..21898
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.74"
                     /tool="antismash"
     misc_feature    complement(22134..22148)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.32"
                     /tool="antismash"
     misc_feature    complement(22166..22180)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.09"
                     /tool="antismash"
     gene            22316..22828
                     /gene="nrdR"
                     /locus_tag="IE241_RS00250"
                     /old_locus_tag="GCM10010324_00490"
     CDS             22316..22828
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538251.1"
                     /locus_tag="IE241_RS00250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00490"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_190019500.1"
                     /transl_table=11
                     /translation="MHCPFCRHPDSRVVDSRTTDDGCSIRRRRQCPDCSRRFTTVETAS
                     LMVIKRSGVTEPFSRTKVISGVRKACQGRPVTEDALAQLGQRVEEAVRATGSAELSTHD
                     VGLAILGPLRDLDLVAYLRFASVYQAFDSLEDFEAAVAELREQRSAATAGDCDGDPQVP
                     APTTAAE"
     gene            22942..25815
                     /locus_tag="IE241_RS00255"
                     /old_locus_tag="GCM10010324_00500"
     CDS             22942..25815
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092898.1"
                     /locus_tag="IE241_RS00255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00500"
                     /product="vitamin B12-dependent ribonucleotide reductase"
                     /protein_id="WP_190019501.1"
                     /transl_table=11
                     /translation="MTETTSGPARGSRSKGNKGGKGLRIERIHTTPGVHPYDEVVWERR
                     DVVMTNWRDGSINFEQRGVEFPDFWSVNAVNIVTSKYFRGATGSPERESSLRQLIDRVV
                     LTYRKAGEQHGYFASPADAEIFEHELTYALLHQVFSFNSPVWFNVGTKQPQQVSACFIL
                     SVDDSMESILDWYKEEGMIFKGGSGAGLNLSRIRSSKELLSSGGNASGPVSFMRGADAS
                     AGTIKSGGATRRAAKMVVLDVDHPDVEAFIETKVKEEEKVRALRDAGFDMDLGGDDITS
                     VQYQNANNSVRVNDEFMKAVETGSKFGLRARMTGEVIEEIDAKGLFRKMAEAAWACADP
                     GIQYDDTINHWHTSPESGRITASNPCSEYMHLDNSSCNLASLNLMKFLRADDAGNQSFD
                     AERFAKVVELVITAMDISICFADFPTEKIGETTRAFRQLGIGYANLGALLMATGHAYDS
                     DGGRALAGAITSLMTGTSYKRSAELAAVVGPYDGYARNADAHKRVMQQHADANGVARRM
                     DDLDTPVWAAATEAWQDVIRLGEKNGFRNAQASVLAPTGTIGLMMDCDTTGVEPDLALV
                     KFKKLVGGGSMQIVNNTVPKALKRLGYQPEQVEAIVAHIAEHGNVIDAPGLKAEHYEVF
                     DCAMGERAISAMGHVRMMAAAQPFLSGAISKTVNLPESATVEEVEEVYFEGWKLGLKAL
                     AIYRDNCKVGQPLSAKKKEEAKAPEAAAPAAAEKVVEYRPVRKRLPKGRPGITTSFTVG
                     GAEGYMTANSYPDDGLGEVFLKMSKQGSTLAGMMDAFSIAVSVGLQYGVPLETYVSKFT
                     NMRFEPAGMTDDPDVRMAQSIVDYIFRRLALDFLPFETRSALGIHSAEERQRHLDTGSY
                     EPTDEDVDVEGLAQSAPRQTEAPKPSQPAAAAAVPAPKQAHNSTELVEMQLGLNADAPL
                     CFSCGTKMRRAGSCYLCEGCGSTSGCS"
     gene            complement(25889..26311)
                     /locus_tag="IE241_RS00260"
                     /old_locus_tag="GCM10010324_00510"
     CDS             complement(25889..26311)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643934.1"
                     /locus_tag="IE241_RS00260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00510"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_190019502.1"
                     /transl_table=11
                     /translation="MTQRPPLPPFDESSARAKVQAAEDAWNSRDPERVALAYTEDCVWR
                     NRHEFITGREEIRAFLRHKWEKERDYRLRKELWSWSGNRISVCFRYEWHDADGQWWRSY
                     GNEQWEFAPDGLMQRREASINDVPITADQREFTPEA"
     misc_feature    complement(26343..26356)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.15"
                     /tool="antismash"
     misc_feature    complement(26377..26390)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.6"
                     /tool="antismash"
     gene            26413..26997
                     /locus_tag="IE241_RS00265"
                     /old_locus_tag="GCM10010324_00520"
     CDS             26413..26997
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604228.1"
                     /locus_tag="IE241_RS00265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00520"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190019503.1"
                     /transl_table=11
                     /translation="MDIAEADGRLLDAAESLFYEHGVQAVGMDRIRAASGVSLKRLYQR
                     FPSKEVLVEAYLRRRDGRWRGALAAYVAARPSVAERPLAVFDWLEEWFGEPDFRGCAFI
                     NAYGELGSGSAGVAGAVRDHKAEVLRYLTGLVRAAGVADPGPVAEQLAVLVDGAITTAA
                     VTGAADSARRAREAAAVLLEAAGAAGAAGAA"
     misc_feature    complement(27041..27058)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            27067..27900
                     /locus_tag="IE241_RS00270"
                     /old_locus_tag="GCM10010324_00530"
     CDS             27067..27900
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641000.1"
                     /locus_tag="IE241_RS00270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00530"
                     /product="arylamine N-acetyltransferase"
                     /protein_id="WP_190019504.1"
                     /transl_table=11
                     /translation="MTGALMWGGGDLDLGAYLTRIGVGATARPDLATLRAVHRGHVAAF
                     PFENLEILLGRPVLLDVKALQDKMVAQRRGGYCYEQNLLLAAALERIGFAFTGIGARIR
                     MGSDKLRPVTHMALKVETDGEQWLCDVGFGGEGLLEPLPFRDGVEEQQGGWTFGIERER
                     EDVRVLRSLHPEGWFDLYAFGPEERFPVDYAVMNHYISTHPHSPFVSRVVVQQTEPRIR
                     RSLVGSMLVTAHSDGSEEQREVPVAELVELLAREFRIELGEADAVTLARVQSSGT"
     gene            27935..28540
                     /locus_tag="IE241_RS00275"
                     /old_locus_tag="GCM10010324_00540"
     CDS             27935..28540
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1258: Antibiotic biosynthesis monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385166.1"
                     /locus_tag="IE241_RS00275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00540"
                     /product="YdbC family protein"
                     /protein_id="WP_190019505.1"
                     /transl_table=11
                     /translation="MLVKWTRCTVVDRRGFERGQRKWAGLLGEPGFRGQGGGWSRGRPH
                     VVHLFGFWESRAFYDSFMARSHDRLAAAQAGTFKNAQVRLFEHRFDVKVGFQPQFADAD
                     VVRIAHCRVREDRVEHFTLMQEKVWNPAMAGSPGMLRGVFGEAPGQEFLVLSVWNSEAE
                     HGKYRAERVERLALRAQIEADVAAIGGDIVALEPSWTV"
     gene            complement(28638..29297)
                     /locus_tag="IE241_RS00280"
                     /old_locus_tag="GCM10010324_00550"
     CDS             complement(28638..29297)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092893.1"
                     /locus_tag="IE241_RS00280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00550"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_229898649.1"
                     /transl_table=11
                     /translation="MSPTPPSSPSPSPATSPPPSAPGTVRPGGRTARTRAAVRDAVLAG
                     LVEYGYPGLTVEYVAEQSGVHKTTLYRRWGGVEGLVADALDLAGEDGWTPPDTGTLRGD
                     LHALAQEIVDTFGDPAAAAAPAAFIAAAFQSERAAEALRGFYCERFARCAPLTERAVAR
                     GEVPAATDHDSLARAVSAPLFFRLFITREPLDAADADQAADVALAAARAGVFTPPA"
     gene            29406..31055
                     /gene="abc-f"
                     /locus_tag="IE241_RS00285"
                     /old_locus_tag="GCM10010324_00560"
     CDS             29406..31055
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="abc-f"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127225.1"
                     /locus_tag="IE241_RS00285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00560"
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="WP_190019507.1"
                     /transl_table=11
                     /translation="MPRADADGGSRVPTQLSLRGVSMSRGDRPLLDDVTFSVRPGERIG
                     IVGENGAGKSTLLRLLAGLEAPDAGAVVAGAEGGVARLGQTPELPPDRTVGDAVDLALA
                     DLRAMERRLRELEAALGEAGPEALAEYGELLTAFEARGGYEADARVDKALHALGLAHIG
                     RERLLGSLSGGEQARLGLACLIAAAPEVMLLDEPTNHLDGAALVWLEDTLRAHPGTVLA
                     VSHDRVFLERVATAVVELDADRRSLVRYGGGYAGFIEEQAAARRRWEQAYEDWSAETAA
                     LEGTAATVARRVAPGRAAKDGNKMAYDRDKGRVQASVSSRVRNAQERLRRLRENPVPRP
                     PEPLRFDARPAAGTAEGTLVALEDVRVGERLAIARMEVRAGERLLVHGANGAGKSTLLR
                     LLAGVTEPDAGTVTRRGSTGYLAQEIPVTRPAERLLAAFARGLAGAEEEHRALLLSYGL
                     FRERDLHVPVGALSAGQRRRLGLARLLARPADLLLLDEPTNHLALGLVEQLEEALAAWS
                     GALVVVTHDRLLRQRFEGRQCEIRAGRALIAG"
     gene            31093..31752
                     /locus_tag="IE241_RS00290"
                     /old_locus_tag="GCM10010324_00570"
     CDS             31093..31752
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973214.1"
                     /locus_tag="IE241_RS00290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00570"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_190019508.1"
                     /transl_table=11
                     /translation="MPRPRRIVLIRHGESVGNVDDTVYEREPDHALSLTERGRKQARDA
                     GAPLRELFGDERVSAYVSPYRRTHQTFHALGLDPGLVRVREEPRLREQDWGNWQDLVDV
                     RRQKAYRDAYGHFFYRFAQGESGADVYDRVGAFLESLWRSFEDPDHPPNVLLVTHGLTM
                     RLFCMRWFHWTVAEFECLSNPGNAETRALLLGPDGRYHLDRPFERWCTPEPYGFTG"
     gene            31764..32663
                     /locus_tag="IE241_RS00295"
                     /old_locus_tag="GCM10010324_00580"
     CDS             31764..32663
                     /EC_number="3.2.2.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004982580.1"
                     /locus_tag="IE241_RS00295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010324_00580"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_190019509.1"
                     /transl_table=11
                     /translation="MTADRFHRALASLRGLALGDALGSQFFVPGNYPSLKRRELPPSPW
                     QWTDDTEMACSVLAVLAGHGRIDQDALARSFAEHHDFDRGYGPAVGRMLRLVREGGDWR
                     ELASALFNGQGSWGNGAAMRIAPLGAWYADDPEQATHQAEISAYTTHQHREAVAGTMAV
                     AAAAALAAAPAGLPAPDALLEGVVALVPRSAVQAGLRRARDMLDYGDPSTVAAVLGCGR
                     RTSAHDTVPFALWSAARNLTSYEAAFWTTAQVGGDVDTNCAIVGGVVAAGERGAPPADW
                     LRRTEDLPDWLPSGVGRR"
ORIGIN
        1 catcgtcccg gcgctgcgcg gcaaggagaa ggaccgccgc acgggcgaca tcctcgccga
       61 gatcgaggcg ctcgtcgccg agggcgtcag cgagatcacc ctgctcggcc agaacgtcaa
      121 cgcctacggc tccgacatcg gcgaccgcga ggcgttctcc aagctgctgc gcgcctgcgg
      181 caggatcgag ggcctggagc gggtccgctt cacctcgccg cacccgcgcg acttcaccga
      241 cgacgtgatc gccgccatgg ccgagacgcc gaacgtgatg caccagctgc acatgccgct
      301 gcagtccggc tcggacaccg tcctgaaggc gatgcgccgc tcgtaccgcc aggagcgctt
      361 cctggggatc atcgagaagg tgcgcgccgc catgccggac gccgccatct ccaccgacat
      421 catcgtgggc ttccccggcg agaccgagga ggacttcgag cagaccatgc acgtggtccg
      481 cgaggcgcgc ttcgcgaacg ccttcacgtt ccagtactcc aagcgccccg gcacccccgc
      541 ggccaccatg gagggccaga tccccaagga ggtcgtccag gcgcgctacg agcgtctcgt
      601 cgccctccag gaggagatct cctgggacga gaacaagaag caggtcggcc gcaccctgga
      661 ggtcatggtc gccgagggcg agggccgcaa ggacgacgcc acgcaccgtc tctccggccg
      721 cgcgcccgac aaccgcctcg tgcacttcac caagcccgac gagccggtcc gcccgggcga
      781 cgtcgtgacc gtcgagatca cctacgcggc cccgcaccac ctgctcgccg agggcccctc
      841 caaggccgtg cgccgtacgc gcgcgggcga tgcgtgggag aagcgcaccg ccgctgccgc
      901 cgccaagccg gccggcgtga tgctgggcat cccggtcatc ggcgcccccg ccccgagccc
      961 cgcccccgct gccgcgggct gcggcggctg cggcgactga cgcaccgtct gcggcccggg
     1021 ggagcgcccc gggccgcgac tgcgcggcgc gtccgtcggg cgtatcgttc ccgccatgct
     1081 cgtcgccgct gccgtatgcc cctgtccgcc gctgctcgtc ccggaggtcg ccgccggggc
     1141 cgcacccgag ctggacggcc tgcgcgccgc gtgcctggac gcgctgggcg tgctggccgc
     1201 cgcgcggccc gaccggctgg tcgtcctggg cccggccccg cagccgggcc gcggaccgca
     1261 cccgcagggc gccaggggat cgttccgcgg actcggcgtg gacgtcgacg tgcgcctggg
     1321 gcagggcccg caggcagggg aacgggagct gccgcagtcc ctggcggtgg ccgcctggct
     1381 gctggagcgt acgcgctggt ccgacgcgcc cgtcgagggt ctgggcgtcg gggagacgct
     1441 ggaggccggg cggtgcctgg aggccggccg cgagctggcc ggagccgacg gacggaccgc
     1501 cctgctggtg atgggcgacg gcagcgcctg ccggacgctc aaggcgccgg gctatctcga
     1561 cgagcgggcg gcggacttcg acgcggaggc ggcccgggcg ctgggcgccg cggacactac
     1621 ggcactcgcc gcgctcgacg gcgggctcgc ccgggaactc aaggccgcgg gacgcgcccc
     1681 gtggcaggtg cttgcagggg ccggcgaggg cgccgggctc aaggggcagc tgctgtacga
     1741 cgaggcgccc tacggggtgg gctacttcgt cgtggcctgg tcgtagtccc gacacctctc
     1801 agacgccctc cggcggctcc tgaaggcctt gcacgggtcc ggggcgcctg ggggactttc
     1861 cgcggccgaa cggccgcgag agggccgcgc agccccctgc aggacatcgg cggccccgtc
     1921 gtccccggcg aagtgaaacc tcccggaacg cagcgacggg gcgcggagcc gatgctccgc
     1981 gccccgtcgc cgacgagggt gcaggccggg acctcccggc agccgctcag ggggcagggg
     2041 tgccggtgcc gccgcccttg ccgccttcct tctcggcgag ccggtcgatg gcgtccttgg
     2101 ccttgccggt gcccgtgtgg atctggctgc tgtacttgcc cttggtcttc tcgtcgacca
     2161 ccttggcggc cttctcgagc ccctgctcga tcttgtcccc gtgctgctgc gcgagatcgc
     2221 cgatcttgtc cttcgcaggg gcgagcttgg ccttgatcgt gtccaacagg cccatggcgc
     2281 cttccctcgt ctttctggtt caagagctac ttacgggcgc cctcaccggc ctcgctgtcg
     2341 acggccttct ccgccgactg ctgcttgggg atctcgaccc cctcggcagc ctgagcctcg
     2401 gcttcggcct cgtcggactc ctccggctcg gtcgcctcgg cccccgtctc ggtggcgtcg
     2461 gccgattccg ccgtcagagt ggcagtcgcc gcctcttcgg ttgacgcctc ggacgacttg
     2521 cggcgaaacc ttgaaaacac gcccatatct actccattac cttactggtg tgagcgaagt
     2581 cccgcgccgc ccggagcgcg ccgttgcacc gcaaccgggc accggcccgt gaaccggctc
     2641 tcggaacctc gcaacaggca acgaccccgg cagcgccgcg tcacgtcgct cgttcgtggg
     2701 gtgcgggtgg ggtttgcgag actgatccag tgagaaaccc ggtgaaaaac gcagttcccg
     2761 ccccgcgggt catcgccgtc gtgggcccca cggcggccgg caagtccgat ctcggcgtcg
     2821 ccctcgcccg gcacctgggc ggcgaggtcg tcaacgccga ctccatgcag ctgtaccggg
     2881 gcatggacat cggcacggcc aagctgaccc tggaggagcg gcagggcgtg ccgcaccgcc
     2941 tcctcgacat ctgggacgtg accgaggccg cgagcgtcgc cgagtaccag cggctggccc
     3001 gcgcggagat cgaccggctc ctcgccgagg gccgcacccc cgtgcttgtc ggcggctccg
     3061 ggctctacat caagggcacc atcgacgccc tggacttccc cggcaccgac ccggccgtcc
     3121 gcgcccgcct ggaggaggag ctcgccgagc agggccccgg cgccctgcac gcccgcctcg
     3181 ccgcggccga cccggccgcc gcccgcgcca tcctgcccgg caacggccgc cgcatcgtgc
     3241 gcgccctgga ggtcatcgag ctgacaggcc ggcccttcac cgccaacctg ccgggcgagg
     3301 agcccgtcta cgacgccctg cagatcggcg tcgacgtcga gcggcccgag ctggacgagc
     3361 ggatcacgct gcgcgtcgac cgcatgtggg aggccgggct cgtcgacgag gtgcgctccc
     3421 tggagcgcca ggggctgcgc gagggccgta ccgcctcgcg cgccctcggc taccagcagg
     3481 tgctcgcctt cctggcgggg gagtgcaccg aggacgaggc gcgcgccgag accgtacggg
     3541 ccaccaagcg gttcgcgcgg cgccaggact cgtggttccg caaggacacc cgtgtccact
     3601 ggctgagcgg ggcggccgac cgcagggcgg aactccccgg gctcgcgctg gcgttgctcg
     3661 aacgggcggt cacagcctga tcacgtgatg gcatcgggac gctacgcgcg ccattccggt
     3721 ctgcgcgggc gtgccatcat cgagcttcga tcgagccgtg aagtccgggt tgggagggcg
     3781 cgtggcgatg gaggccggcc ctcgtgacag accgcaacag ccaccgcgca gggggcacct
     3841 tccggcggta gccggggaag agccggaggc tttgaccccg gacggccccg aggacaccga
     3901 ggggagcgtc gaggccggca ccgccgcgcc cgcgtcgttc cgggagctgc gcccgcagcg
     3961 caggctgcgc atctggcagc tggccccgat cgtcgtgctc gcggccgtcg gctcgctcat
     4021 gttcgccttc cccctcgcct tcgagttcgg cgacggcggg cccgtcgtcg ccatgctcgg
     4081 cctgctcatc agctgctgtg ccgcgggctg gggggtgatg gccgcccgcc gggtcggcta
     4141 cacctggccc ggcatgccgg cccccggctc cgggagccgc ccggactggc gctacgtcgc
     4201 ctcgtacgcg gtcctcgtcg ccgtggtggt cgtgctcgcc gtctggcgcg tggcgcgcct
     4261 gcgctgagcc ggtccgtggc cgtggacagc gccccggggc ctcggcgggg agactgcgac
     4321 cggcccccgt accatcgaac cgtgagcacc gcacagatcg ccttcctcaa gggtcacggc
     4381 accgagaacg acttcgtgat catcccggac cccgacggcc gcatcgagct gtccccgccc
     4441 gccgtcgccc tgctgtgcga ccgccgcgcg ggcatcggtg ccgacggagt gctccgcgtc
     4501 gtacgctccg cagcccaccc cgaggcgcgt gcgatggccg gcgaggcgga gtggttcatg
     4561 gactaccgca acagcgacgg cagcatcgcc gagatgtgcg gcaacggcgt ccgcgtcttc
     4621 gcccgctacc tccaccacgc ggggctcgtc gaggcgggcg acctcgccgt cgccacccgt
     4681 gcgggcgtcc ggcaggcaca catcgccaag ggcggccccg acggggcgcc cggcgacgtc
     4741 accgtcggca tggggcgggc cgtgctcccc gagggcgagg tgaccgtcac cgtcggcggc
     4801 cgcagccgcc ccgcgcgcaa cgtgaacatg ggcaaccccc acgccgtcac tttcgtcgac
     4861 gacctcgccg acgcggggaa cctgttcacc gcccccggcg tcgcccccgc ggacgcgtac
     4921 cccgacggca ccaacgtcga attcgtggcc gaccgcggac cgcagcacgt ggccatgcgc
     4981 gtccacgagc gcggctccgg cgagacccgc tcctgcggca cgggcgcgtg cgcggtgatg
     5041 gtcgccaccg cgcgcaggga cggcctggac ccggccgtca ccggcctgcc tgtcacgtac
     5101 accgtggaca tccccggcgg gcgcctggtg atcagcgagg ctccggacgg cacggtcgag
     5161 atgaccggcc ctgccgtgat cgtcgcggaa ggcaccttcg agtcgtcctg gctggacgtg
     5221 gcgcgcgcct gagggcgctc cccgcatctc acgtcacggg gttccgcgag gctgaaggcg
     5281 ctcccccccc gggggcgccc tggggcgcac tacctctttt ccggtccgtt cgccgaactc
     5341 ccggcggcgt ggctcgctcg aatgggtgat ccgtttcact ctgggcgaga gcgggtgagc
     5401 agcgcgtgat gggctcggta gcatcaagca ccggtacgga ggcgcgcagc cgaccgccgg
     5461 tcgacgctgc cggaggtgcc cccatgagca cagacgccac gcacgaaggt gctcccggcc
     5521 gcagacgcgg ccgcgcccgc ctcgacctga gacggctggg gcgcgcggcg ctcggcggct
     5581 cgggcgcgcg cggcaggctg ccggatgcca tcgaccacgt cgccaaggtg caccgcgccc
     5641 accatccggg cgcggatctc gacatcctgc ggcgggccta tctcctcgcg gagtcctccc
     5701 accgcggcca gatgcgcaag agcggcgagc cgtacatcac ccatccgctc gccgtcaccc
     5761 tgatcctggc ggaactgggc gccgagacga ccaccttgac cgcctccctc ctccacgaca
     5821 cggtcgagga caccgaggtg accctggatc aggtccgcgg gcagttcggc gaggaggtcc
     5881 gcttcctggt cgacggcgtc accaagctgg agaaggtcga ctacggcgcc gccgccgagc
     5941 cggagacctt ccgcaagatg ctcgtcgcca ccggcaacga cgtccgggtg atgtccatca
     6001 agctcgccga ccgcctgcac aacatgcgca cgctcggcgt gatgcggccc gagaagcagg
     6061 cccgcatcgc caaggtcacc cgggacgtgc tgatcccgct cgccgagcgg ctgggcgtgc
     6121 aggcgctcaa gaccgagctg gaggaccttg tcttcgcgat cctccacccc gacgagtacg
     6181 cccgcacccg cgagctcgtc cgcgagcacg ccgccggcct cgcgaccctg gagacgaccg
     6241 cggagcggat gcgggccgtt ctgcgcgagg ccgacatcgc cgccgacgtc ctcgtcaagc
     6301 agcgccattt cgtctccgtg caccgggtgc gcctcaagcg gggcgaggtg accggctcgg
     6361 acctcggcag actgctcgtc ctcgtcgcgg aggacgcgga ctgctacgcg gtcctcggcg
     6421 agctgcacac ctgcttcacg ccgttcatct cggagttcaa ggacttcatc gccaccccga
     6481 agttcaacct ctaccagtcg ctgcacacgg ccgtcgcggg ccccggaggg gaggccgccc
     6541 agatcctcat ccggacccac cagatgcaca aggtcgccga ggccggtgtc gtcgccctgg
     6601 gcaatccgta cgccacgccc gagacgcccg acgccaccga cggggagcgc gtcgacccca
     6661 cccggccggg ctggctctcc cggctgctgg agtggcagca ggccacgccc gaccccgaca
     6721 ccttctggac ctccctccgc gacgagctgg ccctggaccg tgagatcacc gtcttccgcg
     6781 ccgacggcgg cacgatcggc ctgcccgccg ggtcgagctg tgtggacgcg gcctacgcac
     6841 agcacgggga cggcggccac agctgcatcg gggcccgcgt caacggccgc ctcgccaccc
     6901 tcagcacggt cctgcgcgac ggcgacaccc tgcagctgct gatgtcgcgg gacagcgctt
     6961 ccggcccctc cccggactgg ctggagcacg cccgcacccc cgccgcgcgg atcgccatcg
     7021 agcggtggct ggccagccat cccgcggtgg aggccgcccc gcccgtcccg ctcgccccgg
     7081 gccgcccctg cccgccgccc cgggccaccg ctccggccgc gcggtggccc gtcgccgtca
     7141 cggccgacgg agcggacctc gcggccgcga gcgtacggct tgcgggctgc tgtactcccg
     7201 tcccgcccga tgaggtgacc ggcttcgccg tgcgcggggg cgcggtgacg gtgcaccggg
     7261 cacagtgccc tgcagtgcac cgcatggtcg cctccgggcg ggagcccgta ggggtgcggt
     7321 ggagcagccc ggagggcggt ggtgcccgcg actaccgcgt caccctgcgc gccgagtcgt
     7381 tcagcaggcc gcacctcctg gccgacctga cggaggccat cgcggccgag ggggcggcgg
     7441 tcatctcggc ggccgtcgag ccgccccacg agcagcgcgt gcgccacacc tacaccctcc
     7501 agctgccgga cgccgcccag ctgccggagt tgatccgcgc catgcggcgg gtgccggggg
     7561 tctatgacgt cgagcgggcc ggccggccgg tggccactgc gcagctctag ccggggcagg
     7621 cggggaggcc gccgggcggg cgtgcctgcc ccggcagggc ggaggggagc cccgtcgcag
     7681 ccgtcccccg gacgagcacc tctcgtacag ctttccggcg cgctcgtacg ggtggggcgg
     7741 cgccgtgccg ccaccgcgcg gggcctgcgc gctggtagcg atggacgtat gccgcactca
     7801 tccgggaaac ccgcctcggt cccccggcgg tccgtgcgcc gccgtgccgt tctcgccgcc
     7861 gccgtcacgg ccctgctcgt cggcgccgcg gccccacccg ccgcgaactc ccagggcatc
     7921 ggcgaccggc tcttcccgga tctcggcaac cccggctacg acgtggccgc ttacgacatc
     7981 aactttgact accacggcaa cggccggccg ctcgacgccg tcaccaccat cgccgcacgg
     8041 gccaccaccg ggctggaccg cctcaacctc gacttcagca acggcacggt ccgctccgtg
     8101 acggtcaacg gcctgcccgc caagttcgcc tccgccaagg aggacctggt cgtcacgccg
     8161 tccgtcgccc tgccggccga gggcctgttc accgtcgtcg tccggcacac cagcgacccg
     8221 cgcgacggca aggaaggcgg ctggatccgt acgaaggacg ggctggtcat ggccaaccag
     8281 gccgatgccg cgcaccgtgt cttcccgtgc aacgaccacc cctcggacaa ggcccgcttc
     8341 accttccgcg tcaccgcgcc cagggccctg accgtcgtcg ccaacgggct tccggcgggc
     8401 cgtgcggtcc gcgggaccaa cgccacctgg gcgtaccgca gcgagcaccc catggccacg
     8461 gagctggccc aggtctccat cggccgctcc gccgtagtgc accgcacggg gccgcacggc
     8521 ctgcccgtac gggacgtcgt ccccaccgcc gaccggcagc gcgtggagaa gtggacgtcg
     8581 aagacgcccg agcagatcgc gtggatggag gggaaggccg ggccgtttcc gttcgagaac
     8641 tacgggctgc tgatcgccga cgcgtcgacc ggtttcgagc tggagacgca gacgctctcg
     8701 ctcttcgagc gcagcctgtt catccgggac gacatcccct cctggtacct cgagtccatc
     8761 atggtccacg agctcgcaca ccagtggttc ggcgacagcg tcagcccgca cagctggtcc
     8821 gacctctggc tcaacgaggg gcacgccacc tggtacgaag cgctgtacgc cgagtacaag
     8881 ggcggccgga cgctcgacgc ccggatgcgt gccgcgtacg agcactccga cgcctggcgc
     8941 gccgacggcg gcccgcccgc cctgcccaag gcgcccgagc ccggcaagcg gaccagcatc
     9001 ttcaggcccg tcgtctacga cggcggcgcg ctggtgctct acgcgctgcg ccagaagatc
     9061 ggcacggcgg cgttcgaccg gctggagcgc gagtggacca gtgcctaccg cgacgccgac
     9121 gccaccacgg aggacttcac cgccgtcgcc tcccaggtat ccggccagga cctgaaggag
     9181 ttcctgcagg cctggctcta cagcccgaag accccgccca tgcccggtca cgccgactgg
     9241 aaggccgccc ggacggcgcc ccggaaaccc gcgtgacgct ccgccgacca catgggacca
     9301 tcgacgggtc ggcgaggccg ccggcccggg aatctccggg gccgcccgcg cgttgtcgac
     9361 ggtgcggcca ctgcattcgc ggccgccacc tcccaacgat gcaaaggatc aaatgacctc
     9421 ctcttcttcc cttccccagg accggcagag cctcccggag agccttcggg ccgacgccct
     9481 gatggaagag gacgtcgcct ggagccacga gatcgacggg aagcgcgacg gcgagcagta
     9541 cgaccgctcc gagcgagcgg ccctgcggcg cgtggccggc ctctccaccg agctggagga
     9601 cgtcaccgag gtcgagtacc ggcagctgcg cctggagcgc gtggtgctgg tcggcgtctg
     9661 gacgtccggc acggtcaggg acgcggagaa ctccctcgcg gagctcgccg cgctcgccga
     9721 gaccgccggt gccctggtgc tcgacggcgt cgtccagcgc cgcgacaagc cggaccccgc
     9781 cacgtacatc ggctcgggca aggcccagga gctgcgggac atcgtcctgg agtccggcgc
     9841 cgacaccgtc gtctgcgacg gtgagctcag ccccggccag ctcatccagc tggaggacgt
     9901 cgtcaaggtc aaggtggtcg accgcaccgc cctgatcctc gacatcttcg cccagcacgc
     9961 caagtcccgc gagggcaagg cgcaggtctc cctcgcacag atgcagtaca tgctgccgcg
    10021 cctgcgcggc tggggccagt cgctgtcccg gcagatgggt ggtggcggct ccggttcgtc
    10081 cggcggcggc atggccaccc gtggccccgg tgagaccaag atcgagacgg accgccggcg
    10141 gatccgcgag aagatggcga agatgcgccg ggagatcgcg gagatgaaga ccggccgcga
    10201 cgtcaagcgc caggagcgcc ggcggaacaa ggtcccgtcg gtcgccatcg ccggctacac
    10261 caacgccggc aagtcctccc tgctcaaccg gctcaccgga gccggcgtcc tggtggagaa
    10321 cgccctgttc gccaccctgg acccgaccgt gcgccgggcg gagacgccca gcgggcgggt
    10381 ctacaccctc gccgacaccg tcggattcgt ccggcacctg ccgcaccacc tcgtcgaggc
    10441 gttccgctcc accatggagg aggtcggcga ctccgatctc atcctgcacg tggtcgacgg
    10501 ctcgcacccg gtgccggagg agcagctggc cgccgtgcgc gaggtcatcc gcgacgtcgg
    10561 cgcggtcgac gtgcccgaga tcgtcgtgat caacaaggcg gatgcggccg acccgctggt
    10621 cctgcagcgg ctgctgcgga tcgagaagca ctcgatcgcc gtgtcggcgc gcagcggaga
    10681 gggcatcgag gagctcctcg ccctgatcga cagcgagctg ccgcgccccg ccgtggagat
    10741 cgaggccctc gtgccgtaca cccacggctc gctgatcgcg cgggcgcacg ccgacggcga
    10801 ggtcatctcc gaggagcaca ccccggaagg cacgctgctc aaggcgcggg tgcacgagga
    10861 gctcgccgcc gagctccagc ggtacgtgcc cgcggcccgc ggctgacggc cgtacgcggg
    10921 taaagaggta cgagcgccgc ggttatatgc ggaaggcccg ctccccggaa tccggggagc
    10981 gggccttccg catgctgtgg tgtgcgatgc cgcgcggctg ccgcgcctgc ggctaccgct
    11041 gcggtgacat caccggttgg cgaacttccg gctgatggcg tcgtagatgc ccttggcctc
    11101 ggggcccagg cgcgggccgg ccagccaggt gctgttggcc gggccgatcg aggtgttcga
    11161 gaccagcgcc accttgccgt cggggccctt ggcgaaccag ccgccaccgg acgaaccacc
    11221 ggtcatcgtg cagccgatgc ggtacatcgt cggctggttc tggtcgaggc tcagccggcc
    11281 cggcctgtcg atgcagtcgt acatcttctg cccgtcgaag ggcggcgccg ccgggtagcc
    11341 ccaagcgccc atggactgga tggacttcac ctgaggggcg ttgaagtcga ccgtgagggc
    11401 gttgccgacg gtctcctcca gggacttgcc ggagccggcc tcgggcttca cgtgcagcac
    11461 ggagtagtcg tacggggcac ccgcgccacc ggtctcggca ccctgcgtga tccactgcgc
    11521 ggaggtctgc gcccagtccg cccaccacac gccgtacgga gcgacgtcct gcaccggcgc
    11581 gctgttgacc tgggcgcccg gcaggccctt gtcgttgtag gacggcacga aggcgatgtt
    11641 gcggtaccag ccgcccttct tgccggcgtg cacgcagtgg cccgcggtcc acaccatgtt
    11701 ggacttgccg gggtgcgccg ggtccttgac gaccgtggcc gagcagacca tgtggccctc
    11761 ggggctgtcg aagaagacct tgccgaccgg ggccgcgttg ttgtggtacg gcacggtgac
    11821 ggacttggcc tggaccggcc gcggctcggg gtcggtcacg ccctggtcac cggaggcgcc
    11881 cggcgccgtg cccggcgcac cctgcgtggc gagcgtcttg tcgctggggc gggcgtcctt
    11941 catcgtgtcg ggcttccagt ggcccttgat gatcgggttg atgaagtcgc gggcctcgcg
    12001 gagccactgc tccttgtccc agttcttcca ggcgccgttc ttccacttct ccaggtcctt
    12061 cagggaactg ggaaggttct tgggcagctc gaggccctcg tcgcccttct gcgaggcggt
    12121 tgcgctgggc ttgtcgctcc ccgcggcctc gtcgtcggtc gggccgcacg cggtggcggt
    12181 cagcgccagc gcggccgtca gagcggccgc ggccagcgca ggcctgcgga tggatggcat
    12241 ggagtgggtc cccctgatcg ttctgttcgg acgtgtccgc aatgtcgcgg ccacgctgtg
    12301 gagttgtcat gcaccgcccc agcgggggag gcagggcccc actatgccgg tgcgtgggga
    12361 gacgggaacg ggcgggtcca tggttccgct gtgaaggatc ttgacggtga gccgtgatcc
    12421 gccgcgcgcg gcgtcgttgg tacgtacggg ggagtgccga tcagcgttta gcagcagcag
    12481 gaggagccag agccgtggcc ttgacccagc taccgcctac ggagccgtcg gccgcagcgt
    12541 acgaaggcat cctccggcgg cagtcggccc gcgaatcggc cgcccgtacg tatgcccggt
    12601 cgctgcccat cgtgccggtg cgcgcccggg ggctgacgat cgagggtgcg gacggccggc
    12661 ggtatctcga ctgcctctcc ggggccggct cgctcgcgct ggggcacaat cacccggtcg
    12721 tgctggaggc catccgctcc gtccttgact ccggcgcgcc cctgcacgtg ctcgatctgg
    12781 ccaccccggt caaggacgcc ttcacggacg agctgttcgc cacgctgccc cgggagctgg
    12841 cggagtcggg ccgcatccag ttctgcggcc ccgccggcac cgacgccgtg gaggccgcct
    12901 tcaagctcgt gcgcaccgcg accggccgcg acggcctgct cgccttcacg ggggcctatc
    12961 acgggatgac ggagggggcg ctcgccgcct cgggcgcggc gccgagcgtg cgggtgacca
    13021 ggctgcccta tccgcaggac taccgctgcc cgttcggcgt cggcggggag agcggggcgc
    13081 ggctcgccgc ccgctggacc gagagcctcc tggacgatcc caagagcggg gtgcgccggc
    13141 cggccgcgat gatcgtcgaa cccgtgcagg gcgaaggcgg cgtgctgccc gcgcccgaag
    13201 gctggctgcg ccggatgcgc gagctcactg ccgcacgctc catcccgctc atcgccgacg
    13261 aggtgcagac gggagtgggc cgcaccgggg ccttctgggc ggtcgagcac agcgggatcg
    13321 tgccggacgt gatggtcctg tccaaggcca tcggcggcag cctcccgctc gccgtcatcg
    13381 tctaccggga cgacctcgac acctggcagc cgggcgacca cgccggcacg ttccggggca
    13441 atcagctcgc gatggccgca ggagcggcga cgctgcgcca cgtcagggag aacggcctcg
    13501 ccgagcgcgc cgcatcgctg ggcgcgcgca tgctggagcg gctgcggcgg atggcggggg
    13561 agtacgagtg catcggcgag atccgcgggg ccgggctcat gatcggcatc gaattcgtcg
    13621 ccccggaggg ggaggccggt ccggctcccg aggggcacga cgccggtgcc ccggacgcgt
    13681 ggcaccgtcc ggggcaggag ccgggtgaca acgctgccac cggcccgctg cccgcttccc
    13741 ccgtgcgggc cgcggccgtc cagcgcgagt gtctgcgccg gggcctgatc gtcgaactgg
    13801 gcggccgtca ctcctgcgtc gtccgcctcc tgccgccgct gaccatcacc gacgagcaga
    13861 ccgaggcggt cctggagcgg ctcgccgacg ccgtcgccgc ggtctgccgg cccggtcgcc
    13921 gcatccccgc cccgagcaca ccgaaggagg caggcgccgc atccccggcc tgacgccgcg
    13981 acgtgcacgc cgtacaccgc atgaacgcat ccaccgggac cggtgcttcc acggccggcc
    14041 aggacagcga tccggccccc gagcggcagg ccgtggtctc cgccgtcccc cgccagggcg
    14101 gcggcccgtg cggcgggatc ccggacacgg gccctccctg cgcgcccgac cctctggaac
    14161 atcccgaccc cgccgtcgcg gccgacgccg ccgccgtgga gaacctcctg cgctgctggg
    14221 tccgcgagac cggcgtcccg cggcccggcg gccccgaact gcacctgccg ctcgccgcga
    14281 gcgggacagc cctgcgcgtc cccgtggcct actggtccgc cgccggatgg catcgcttcg
    14341 gcccgccggc cctggcggac gggcccggtg acgcccctgc cgtggacgcc gtcaccctcg
    14401 cggcgctcct cggccgcgaa gccgcccacc gtgccgcccg cgcaggatgc accggcacgg
    14461 gcgagacggc ggaactcgtc ggcagggtgg cggactccgc gcgccgtacg gcagccttcc
    14521 tcgccgaccg gcgggcccgc cccgccgacc cggacgcggg cgagctcttc ctctacgccg
    14581 agcagtccct gctcctcggc caccccctcc accccacacc caagagccgc gaaggcctct
    14641 ccgacgccga gtcgcacgcc tactccccgg agctgcgcgg ggccttcccg ctgcactgga
    14701 tggccgtcca ccgctccctg ctcgccatgg actcggcgtg gaccgaacgg gggcggcccg
    14761 tcgacgcccc caccctcgcc gcccggctcg ccggcccgga gctgcgcctg cccgaggaca
    14821 ccgcggcgct gccgctgcac ccctggcagg cccatgacgt ccgcagccgc cccggcgtcc
    14881 gccggctcct ggacgccggc ctgctgcacg acctcggccc cctcggcgcg ccctggtacg
    14941 ccacctcctc cgtacggacc gtccaccggc ccggcgcccc cgcgatgctg aagctctccc
    15001 tcgggctgcg catcaccaac tcccgccggg agaacctccg caaggagctg caccgcggcg
    15061 tcgaagtgca ccgcctgctg cgcagcggcc tcgccgagca gtggcgcgcg gcctgcccgg
    15121 gcgggctcgg cttcgacgtc gtccgcgacc cagcctggct cgccgtggac acccccgagg
    15181 gcgccccgct gaccggcctc gacgccgtca tccgccacaa ccccttcggc cccggtgacg
    15241 acgccgtctg cctcgccggg ctcgtatcgc cccggccctg gcccgccgct gtgccccaga
    15301 agcaccccgg cgggcccggc gggcgtccgg ccctgcgctc gcgtctggca cacatcgtgg
    15361 cccgcctcgc gcaccgcacc ggccgccccg cgggcgccgt ctccgcggag tggttcctgc
    15421 gctatctgga ggcggtcgtg cgccccgtgc tctggctgga cggcgaggcg ggggtcgccc
    15481 tggaggccca ccagcagaac acgctcgtcc tcctggaccg cgagggctgg cccgcgggcg
    15541 gccgctaccg cgacaaccag ggctactact tccgcgcctc ccgccgggac gccctcgacc
    15601 ggcggctgcc cggaatcggc gcggagagcg acaccttcgt gtccgacgag gtcaccgacg
    15661 aaaggttcac ctactacctc ggcatcaaca acgtcctcgg cctgatcggg gcgttcggcg
    15721 cgcagcgcct cgccgacgaa cagatcctgc tggccgcact gcggcgcttc ctccaggacg
    15781 ccgcgtccgg cccggccgcc ggccgctcga ccctgcccgc ccgccttctc gaagcgccga
    15841 ccctgcgctg caaggccaac atgctgacca ggctgcaggg gctcgacgag ctcgtcggcc
    15901 cggtcgacac ccagtccgtc tacgtcacca tcgccaaccc cctggtcacg tcggcccgat
    15961 gaccggcgcg agccccggcc ccgggcgaac ggggcccttg aggacacggg cccccgcggg
    16021 cccacgggat cccggacacc gaggggatcc tccgagagga gagcgtctcc gtgccgccca
    16081 ccgaccccag cgaaggcccg ggcaccggcc cgggccccga ccaccccggc tcccggacca
    16141 ccggccttgc gggcccgggc gtcgctgacg ccgcccccgc cggcgccggc ccgccgaccg
    16201 acaacgagac caccctcgaa ctgcagctgt ccgaagagtt catcgaactc atcgaccacg
    16261 gcgccccgga gccggccgcg atcaccgcgg gccgcgggcc cgccggggcc atcggcccgg
    16321 gctccgacct cctcgactcc ctcgccgact gggggcccgc cgacaccggt gcgggcacct
    16381 tccagctcgt gccggtccgt gtcgagcgcg atctgcggct catcacgcgc tggatgaacg
    16441 acccggccgt cgcggcgttc tggaagctgg gcgggcccga gagcgtgacc gaggcccacc
    16501 tgcgcgccca gaccggcggc gacggccgca gcatcccctg cctcggggtg ctcgacggcg
    16561 tgccgatgag ctactgggag gtctaccgcg ccgacctcga ctccctcgca cgccactacc
    16621 cggcccggcc gcacgacacc gggatccacc tgctgatcgg caaggtcgcc gaccggggcc
    16681 gcggtgtcgg cacccgcctg ctgcggaccg tcgccgacct tgtcctggac caccggccgt
    16741 cctgcgcgcg cgtcgtcgcc gaacccgacc tgcgtaacac cccgtgcgtc tccgcgttcc
    16801 tgagcgcagg cttccggctg acggcggaaa tcgaccttcc ggacaagcgc gcggccctgg
    16861 tcgtccgtga ccgcgccctg cgcaccctcc tctaagaccg catctgccgg taggaccgca
    16921 tctaccggcc cgctgcattc cccacccatc ggcctactca aggagccccc ttgtctcctt
    16981 cgccccggtc cgaacaattc gacggccgct cccgcccctc ggacacctcc gcccgtcccg
    17041 cccgtcccgc ccgccccgcg cgcgcgggcc gccccggcgg tccggagtgg tccctcgcgg
    17101 gcgcccgtct gctcgccaag atgctcggcg aactcagcta cgagggcgtg ctgacccccg
    17161 agcccgacga cgcggccgag gcacccgcca ccgcctaccg gctgtcctta acggatgacg
    17221 tgacctaccg cttccgcgcc cgccggagcg cgtacggcca ctggacggtc gacccggact
    17281 ccgtcacccc ctcccaggac cccctccgct tcctcgccct cgcccacgac accgtcctcg
    17341 gcctctccgg cgacaccacc ggccacctgg ccagggaact cctcgccacc ctctccgccg
    17401 acacccgcct ccgggcgagc gccctcagcg ctgcgcacct cgccgacctc gactacgccg
    17461 cactggaagg ccaccagacc ggccacccct ggctgatcgc caacaagggc cggctcggct
    17521 tctccgcctc cgacaccgac cggtgggccc cggaggcccg caccccgcgc cgcctgccct
    17581 ggatcgccgc gcaccgcagc ctcgcgcact accgggccgt ccccgcactg gccacccccg
    17641 acctcctcta cgccgaagag ctcgcccccg gcacccgcgc cgccttcgcc cgcaccgtcg
    17701 ccgaccacgg ccgcgacccc gccgactacc tctggctccc cgtccacccc tggcagtggg
    17761 acgagaccgt ggcccccctc ttcgcgccct gcctcgccga cggatccatc atccccctgc
    17821 ccactgacaa cgacctccgg ctgccccagc agtccgtccg caccttcctc aacaccagca
    17881 ggccgcacgc ccggaccgtg aagctcccgc tctcgatcct caacacgctc gtctggcgcg
    17941 gcctgccgac cgagcgcacc ctcgccgctc ccgcggtcac cgcctgggtc cactccctcc
    18001 gcgactccga cgacttcctc cgggacgaga cccgggtgat cctcctcggc gagaccgcct
    18061 ccgtgaccgt cgagcacccc ctctacgacc gcgtgcccgg cgtcccctac cagtacaagg
    18121 agctgctcgg ctgcatctgg cgcgagcccc tcggccccgc cctcgccccc ggggagcgcg
    18181 cccgcaccct cgcggccctg ctgcacaccg accccgccgg ccgctccttc accgccgagc
    18241 tcgtccaccg ctccggcctg gccccggccg actggctgag ccgcctcttc gccgcgctgc
    18301 tcccgccgct cctgcgcttc ctctaccgct acggcaccgt cttctccccg cacggcgaga
    18361 acgccatcgt cgtcttcgac gagaacgacg tgcccacccg gctcgccgtg aaggacttcg
    18421 tcgacgacat caacatcagc gccgttcccc tgcccgagca cgcctcgatg cccgacgacg
    18481 tgagggccgt gctgctcacc gaaccgcccg ggttcctcac ccagttcatc cactcagggc
    18541 tcttcgtggg ggtcttccgc tatctcgcgc cgctgtgcga ggaacagctc ggagtgccgg
    18601 aggccgcctt ctggtcgctc gtgcggacgg agatcatgcg gcaccacgag cgctttccgc
    18661 ggatgaagga ccgctacgag accttcgacc tgctcacccc gcggatcgag cggctctgtc
    18721 tcaaccgcaa ccggctgcat ctcgacggct accgcgaccg cccggaacgc ccgcacgcgg
    18781 ccgtccacgg caccgtgccc aatccgctgc acattccgtg acggcgccgc cgatgtcagt
    18841 accgcccctt agggtggaac agctatgact gcctcctcct cgccctccct caccgacctg
    18901 ctgcacgccg ccgtcaccgc tgtcggcggc accgagcggc ccggtcaggt caccatggcc
    18961 gaagccgtcg ccgaagccgt cgacggcgac tcccacctgc tcgtacaggc gggcaccggc
    19021 accggtaagt ccctcggcta tctggtgccg gccctggccc acggcgagcg cgtggtggtg
    19081 gccaccgcga cgctggcgct ccagcgccag ctcgtggagc gcgatcttcc gcgaacggtg
    19141 gatgccctgc agccgctgct gcgccgccgc ccgcagttcg ccatgctcaa gggccggtcg
    19201 aattacctgt gcctgcaccg gctgcacgag ggagtgccgc aggacgagga ggaggggctc
    19261 ttcgacccct tcgaggccgc ggctccctcc agcaagctcg gcaaggacct gctgcgcctg
    19321 cgcgactggg ccgacgagac ggagacgggc gaccgcgacg atctcacccc cggtgtctcc
    19381 gaccgggcct ggtcccaggt gtcggtcacg tcccgggagt gcctgggcgc ctcgaagtgc
    19441 gcgtacggtg ccgagtgctt cgcggaggcc gcccgggagc gggccaagct cgccgacgtg
    19501 gtggtcacca accacgccct gctggccatc gacgccatcg agggcgcccc ggtgctcccc
    19561 ggccatgagg tcctcatcgt cgatgaggcc catgagctgg tctcccgggt caccggcgtc
    19621 gccaccggcg agctcacccc cggccaggtc aaccgcgcgg tgcggcgcgc ggccaagctc
    19681 gtcgacgaga aggccgccga tgccctgcag accgcggccg agagcttcga gcgcctgatg
    19741 gagctggccc tcccgggccg gctggaggag atccccgagg atctcgggta cgccctgatg
    19801 gcactgcgcg acgccgcccg gacggtcatc tcggccatcg gcaacacccg cgacaagtct
    19861 gtccaggacg aggacgccgt ccgcaagcag gccctggcct ccgtggagaa catccacgcg
    19921 gtcgccgagc gcatcacgga gggctccgag tacgacgtcg tctggtacga gcgccacgac
    19981 cgcttcgggg cttccctgcg cgtcgcgccg ctctccgtct ccgggctgct gcgcgagaag
    20041 ctcttcagcg agcggtccgt ggtgctcacc tcggccacgc tcaagctcgg cggtgacttc
    20101 aacggcgtgg ccgcctccct gggcctggcc cccgagggca ccggcggcgc ggagagcccg
    20161 gagtggaagg gcgtcgacgt cggctcgccg ttcgattatc ccaagcaggg catcctctac
    20221 gtcgcccggc atctgtccca gcccggccgc gagggcagcc gtacggacat gctcgacgag
    20281 ctggccgagc tggtgcaggc cgccggcggc cggacgctcg ggctgttctc ctcgatgcgg
    20341 gccgcccagg ccgcggccga ggagctgcgc ggccggctcg acgtgccgat cctgctgcag
    20401 ggcgaggaga cgctcggcga gctgatccgg aatttcgccg ccgacgcccg tacgtgcctg
    20461 ttcggcaccc tgtccctgtg gcagggggtc gatgtgccgg ggccgagctg ccagctggtg
    20521 gtgatggacc gggtgccctt cccgcggccg gacgatccgc tgatgagcgc ccggcagaag
    20581 gccgtggagg aagcgggcgg caacggcttc atggccgtgg cggcgacgca tgcggcgctg
    20641 ctgatggccc agggcgccgg ccggctcgtc cgggcctcgg gggaccgcgg cgtcgtcgcc
    20701 gtgctggacc cccggctggc cacggcccgc tatggcggct tcctgaggtc gtccctgccg
    20761 gacttctggt acaccacgga ccgtaaccag gtgcgccgct ccctggcggc gatcgacgag
    20821 gcggcgaagg cggagggccg ctaggcccgg gccgggccta gcggcccggc ctgcgaagga
    20881 aagagcccgg acaagagtcg cggacaaaag gaaaagagcc ccggaaccgg cgcaggtggt
    20941 tccggggccc ggccttgcgg ccctgtgccc tcacacgcgg cgcagcaccg ccacgacctt
    21001 gccgaggatg gtggcctcgt cgccggggat gggctggtag gcggcgttgt gcggcagcag
    21061 ccacacatgg ccgtcctcgc gcttgaagcg cttgaccgtg gcctcgccgt cgagcatggc
    21121 ggccacgatg tcgccgttct ccgcgacggg ctggcggcgg accgtcaccc agtcgccgtc
    21181 gcagatggcg gcctcgacca tggagtcgcc gacgaccttc aggacgaaca gctcgccgtc
    21241 accgaccagt tggcggggga gcgggaagac gtcctcgacg gactcctcgg cgaggatggg
    21301 gccacccgcg gcgatccggc cgacgagcgg cacataggag gcggcgggct ttccggtggt
    21361 gtccgtgggc tgcgagctgg gctggtcgga accgcgtacc tcgtaggccc gggggcggtg
    21421 cggatccctg cgcaggaagc ccttgcgctc cagggccatg agctggtgcg ccacggacga
    21481 ggtgctcgac agcccgaccg cctggccgat ctcccgcatg gagggtgggt agccccggcg
    21541 ctggacggaa tccctgatca cttcgatgac ccgccgttgg cggtcggtga gacccgagct
    21601 gtcggcccgg atccctggag gtcgtcccgg gagggcccga gcgggcttct gcccctcggt
    21661 gctcatggct gcgtcattca tcgggtgtgc ctggtcgagt cggttctggg agcggtcctg
    21721 ggcggtgatt gtggcgctgt ctgcggtggt ggtcacgtcg gcccctctcg aaatgttctc
    21781 cctagctgga caacggtagt tgctttcgaa aggttgcgcc aaacacacgt tcgagtgaaa
    21841 tatcgaagtt tgcctgacgt gatcagcgct gagggtgtac ggctgaagat caattcgacc
    21901 tattacggta cccttcggtg cgaagcgcac cgagcgggtc cccggcccgt aagggccttg
    21961 cgcaggcccc gtgcgggccc cgccgacccg gcccgggcgg gccggcgcga cggttccgcg
    22021 gtggccccag tgtgtcatca aagcccccgt gcccctgtgg gcggggcggc tcgcgtaggg
    22081 tcgtgaccgg tcctcgcggc cgcgacacgc gtccggcgcg gctcaccgca cggcaccaga
    22141 tctagtggtt tgattggcgg cggccgccca caggttgtgg tcgaggggtg tcgccggtca
    22201 tttgaggccg ccgtcatcgc ctatgctggg gtctgcttcg caaggccccc gttcgagggt
    22261 ccgccgaggc tgaagatcgt gcacagtcct acgagggtga ggagggtgga gagccatgca
    22321 ctgccccttc tgcaggcacc ccgacagtcg cgtcgtcgac agccggacca ccgatgacgg
    22381 ctgctcgatc cgccggcggc gacagtgccc cgactgctcc cgtcgtttca cgaccgtgga
    22441 gaccgcgtca ctgatggtga tcaagcggag cggggtcacc gagcccttca gccgcaccaa
    22501 ggtcatctcg ggagtgcgca aggcgtgcca gggccgcccg gtcaccgagg acgccctggc
    22561 ccagctcggt cagcgggtcg aggaggcggt gcgtgccacg ggcagcgccg agctctccac
    22621 ccatgacgtg ggcctggcca tactcggccc cctccgggat ctcgacctgg tcgcgtatct
    22681 gcggttcgcg tccgtgtacc aggcgttcga ctccctcgag gacttcgagg ccgccgtcgc
    22741 ggagctccgc gagcagcggt ccgccgcgac cgccggcgac tgcgacgggg acccgcaggt
    22801 tcccgcgccc accacggccg ccgagtagcc gcggccatca cagacctgcc cggcgcgccg
    22861 cgcgcccggg cgaagaacag acatagcgcc ccacggaaga attgggcgca ttagggcgtt
    22921 ttgcccgtag agggaggcgg catgaccgag acgacgagcg gcccggcacg aggttcccgc
    22981 tccaagggga acaagggcgg caagggtctg cgtatcgagc gcatccacac cacccccggt
    23041 gtgcacccgt acgacgaggt cgtctgggag cgccgtgacg tcgtcatgac caactggcgc
    23101 gacggctcga tcaacttcga gcagcgcggc gtggagttcc ccgacttctg gtcggtgaac
    23161 gcggtcaaca tcgtcacgag caagtacttc cgtggcgcca cgggttcgcc cgagcgcgag
    23221 tccagcctcc gccagctcat cgaccgggtc gtgctgacct accgcaaggc gggcgagcag
    23281 cacggctact tcgcctcccc ggcggacgcc gagatcttcg agcacgagct gacctacgcc
    23341 ctgctgcacc aggtcttcag cttcaactcc ccggtctggt tcaacgtcgg caccaagcag
    23401 ccccagcagg tctccgcctg cttcatcctc tccgtcgacg actccatgga gtcgatcctc
    23461 gactggtaca aggaagaggg gatgatcttc aagggcggct ccggcgccgg cctgaacctc
    23521 tcccgcatcc gctcctccaa ggagctgctc tcctccggcg gcaacgcctc cggcccggtc
    23581 tccttcatgc gcggcgccga cgcctccgca ggaacgatca agtcgggcgg cgccacgcgc
    23641 cgtgcggcca agatggtcgt cctcgacgtc gaccaccccg acgtcgaggc cttcatcgag
    23701 accaaggtga aggaggagga gaaggtccgc gccctgcgcg acgccggctt cgacatggac
    23761 ctgggcggcg atgacatcac ctccgtccag taccagaacg ccaacaactc cgtccgcgtc
    23821 aacgacgagt tcatgaaggc cgtcgagacc ggctcgaagt tcgggctgcg cgcccggatg
    23881 accggtgagg tcatcgagga gatcgacgcc aagggcctct tccgcaagat ggccgaggcc
    23941 gcgtgggcct gcgccgaccc gggcatccag tacgacgaca cgatcaacca ctggcacacc
    24001 tcgccggagt cgggccggat caccgcgtcc aacccgtgca gcgagtacat gcacctggac
    24061 aactcctcgt gcaacctcgc ctccctgaac ctcatgaagt tcctccgcgc cgacgacgcc
    24121 ggcaaccagt cgttcgacgc cgagcgcttc gccaaggtcg tcgagctcgt catcacggcg
    24181 atggacatct ccatctgctt cgccgacttc ccgaccgaga agatcggcga gaccacccgc
    24241 gccttccgcc agctgggcat cggctacgcc aacctcggcg ccctgctgat ggccaccggc
    24301 cacgcgtacg acagcgacgg cggccgcgcc ctcgccggtg ccatcacctc cctgatgacc
    24361 ggcacctcct acaagcgctc cgccgagctg gccgcggtcg tcggcccgta cgacggctac
    24421 gcccgcaacg ccgacgccca caagcgcgtc atgcagcagc acgccgatgc caacggtgtc
    24481 gcccggcgca tggacgacct ggacaccccg gtgtgggccg cggcgaccga ggcctggcag
    24541 gacgtcatcc gcctcggtga gaagaacggc ttccgcaacg cccaggcgtc cgtgctggcg
    24601 cccaccggca ccatcggcct gatgatggac tgcgacacca cgggcgtcga gccggacctg
    24661 gccctggtca agttcaagaa gctcgtcggc ggcggctcga tgcagatcgt gaacaacacg
    24721 gtgccgaagg cgctcaagcg cctgggctac cagccggagc aggtcgaggc gatcgtcgcc
    24781 cacatcgccg agcacggcaa cgtcatcgac gcccccggtc tgaaggccga gcactacgag
    24841 gtcttcgact gcgccatggg cgagcgcgcg atctccgcca tgggccacgt gcgcatgatg
    24901 gccgccgcgc agccgttcct gtcgggcgcg atctccaaga cggtgaacct gccggagtcg
    24961 gccactgtcg aggaggtcga ggaggtctac ttcgagggct ggaagctcgg cctgaaggcc
    25021 ctcgcgatct accgcgacaa ctgcaaggtc ggccagccgc tctccgccaa gaagaaggag
    25081 gaggccaagg cccccgaggc cgccgccccc gccgccgcgg agaaggtcgt tgagtaccgc
    25141 ccggtccgca agcgcctccc caagggccgc ccgggcatca ccacctcctt cacggtgggc
    25201 ggcgccgagg gctacatgac cgccaactcc tacccggacg acggtctcgg tgaggtcttc
    25261 ctgaagatgt ccaagcaggg ttcgaccctc gcgggcatga tggacgcctt ctcgatcgcc
    25321 gtctcggtcg gcctgcagta cggcgtgccg ctggagacgt acgtctcgaa gttcaccaac
    25381 atgcgcttcg agccggccgg catgaccgac gacccggacg tgcggatggc gcagtcgatc
    25441 gtcgactaca tcttccgtcg cctggcgctg gacttcctgc ccttcgagac ccgctcggcg
    25501 ctcggcatcc actccgccga ggagcgccag cgtcacctcg acaccggttc gtacgagccg
    25561 accgacgagg acgtcgacgt ggagggcctc gcccagtccg cgccgcgcca gaccgaggcc
    25621 ccgaagccgt cccagccggc tgccgccgcc gcggtcccgg cgccgaagca ggcccacaac
    25681 tccaccgagc tggtggagat gcagctcggc ctgaacgcgg acgcgccgct gtgcttctcc
    25741 tgcggcacga agatgcgccg tgcgggcagc tgctacctct gcgagggctg cggctcgacc
    25801 agcggctgca gctgacgcgg agcccgctcc gcgctgaata gcgaatgaag gcggtggccg
    25861 gaggaatttc ctccggccac cgccttcgtc atgcctccgg ggtgaattcc ctctggtccg
    25921 cggtgatcgg cacgtcgttg atgctggcct cgcggcgctg catcaggccg tccggagcga
    25981 attcccactg ctcgttcccg tagctgcgcc accactgccc gtcggcgtcg tgccactcgt
    26041 accggaagca gaccgagatc cggttgccgg accacgacca gagctccttg cgcagccggt
    26101 aatcccgttc cttctcccat ttgtggcgga ggaaggcccg gatctcttcg cggccggtga
    26161 tgaattcgtg ccggttccgc cagacgcagt cctcggtgta ggcgagggcg acccgttcgg
    26221 ggtcgcggct gttccaggcg tcctcggcgg cctggacctt ggcccgggcg gaggattcgt
    26281 cgaagggtgg caggggcggg cgctgagtca tggcatgcct tccggacgca cgggaagaat
    26341 ggagaacgtt cgttctccgc ttccgctgta ccctagagaa cgatcgttct ccgcgccagc
    26401 ccgggagggg caatggacat cgccgaagcc gacggccgac tgctcgacgc agcggagtcc
    26461 ctgttctacg agcacggtgt gcaggccgtg gggatggacc ggatccgcgc agcgtccggc
    26521 gtctcgctca agcgcctcta ccagcgcttc ccgtccaagg aggtcctggt cgaggcctat
    26581 ctgcggcgcc gcgacggccg ctggcgcggc gccctggccg cctacgtcgc cgcgcgcccc
    26641 tcggtggcgg aacggcccct cgcggtgttc gactggctgg aggaatggtt cggcgaaccg
    26701 gatttccgcg ggtgcgcgtt catcaacgct tatggcgaat tgggctcggg atccgcgggc
    26761 gtggccgggg ctgtacggga tcacaaggcc gaggtgctcc gatatctgac cggcctcgta
    26821 cgcgctgccg gcgtcgcgga ccccgggccg gtggccgagc agctcgccgt cctggtcgac
    26881 ggtgcgatca ccacggcggc ggtcaccgga gcggcggact ctgcacgcag ggcccgggaa
    26941 gccgccgcgg tattgctgga ggctgcgggc gctgcgggcg ctgcgggcgc tgcgtgacgg
    27001 aggccgaagg cggtccgtgc cgagggtgaa tactgtcggg tgtccggtcg aggggagaga
    27061 gcggtaatga cgggtgcgct catgtggggc ggcggggatc tggacctggg cgcctatctg
    27121 acgcgaatcg gagtcggggc gacggcccgg ccggacctcg cgacgctcag ggcggtgcac
    27181 cgcggccacg tggccgcctt ccccttcgag aacctggaaa tcctgctcgg gcgaccggtt
    27241 ctgctggacg tcaaggccct tcaggacaag atggtcgcgc agcgccgcgg aggctactgc
    27301 tacgagcaga atctgctgct cgccgccgcc ctggagcgca tcggattcgc tttcacgggt
    27361 atcggcgcgc ggatcaggat gggcagcgac aagctgcgcc cggtcactca tatggcgctc
    27421 aaggtcgaga ccgacggcga acagtggctg tgcgacgtcg gattcggcgg ggaggggctg
    27481 ctggagcccc tccccttccg cgacggcgtg gaggagcaac agggcggctg gacgttcggc
    27541 atcgagcggg agagggagga cgtacgggtc ctgcgctcgc tccaccccga gggctggttc
    27601 gacctgtacg ccttcggtcc ggaggagcgt ttcccggtcg actatgcggt gatgaaccac
    27661 tacatctcca cgcacccgca ctcgcccttc gtctcgcgcg tggtggtaca gcagacggag
    27721 ccccgcatac ggcggagtct ggtgggctcc atgctcgtca ccgcccactc cgacggctcc
    27781 gaggagcaac gggaggtgcc cgtggcggag ttggtggagc tgctcgcgcg tgagttccgg
    27841 atcgagctcg gcgaggccga cgccgtgacc ctcgcacggg tgcagtcctc cggtacgtga
    27901 ctgcgggccg ctgcccgggc cgtacgatgg cgcggtgctg gtcaagtgga ctcgctgcac
    27961 cgtggtcgac cgccgcggct tcgaacgcgg acaacgaaaa tgggcgggcc tgctcggcga
    28021 gcccgggttc cgggggcagg gcggaggctg gagcagaggg cgtccgcatg tggtgcacct
    28081 gttcggcttc tgggagagcc gggcgttcta cgactccttc atggcgcgct cccacgacag
    28141 gctcgcggcg gcccaggccg ggaccttcaa gaacgcccaa gtgcggcttt tcgagcaccg
    28201 attcgatgtg aaggtcggct tccagccgca gttcgcggat gcggatgtgg tgcggatcgc
    28261 ccactgccgg gtccgcgagg accgcgtgga gcacttcacc ctgatgcagg agaaggtgtg
    28321 gaacccggcc atggccgggt cgccggggat gctgcgcggc gtcttcgggg aggcgcccgg
    28381 ccaggagttc ctggtgctgt ccgtgtggaa ctccgaggcc gagcacggga agtaccgcgc
    28441 ggagcgggtc gagcggctcg ccctgagggc gcagatcgag gccgacgtgg cggcgatcgg
    28501 cggcgacatc gtcgcgttgg agccttcctg gacggtgtga cggccgggcc gggccgggcc
    28561 gagtcgggtc gagtcgggtc gagtcgggtc gagtcgggcc gagtcggtgc cggctgagcg
    28621 tcatgctcgc ccgggcgtca ggccggtggt gtgaagacgc cggcgcgggc tgcggcgaga
    28681 gcgacgtccg cagcctggtc ggcgtcggcg gcgtccaggg gctcccgggt gatgaacagc
    28741 cggaagaaca gcggggccga tacggcccgg gcgagggagt cgtggtcggt tgcggccggc
    28801 acctcgccgc gggccacggc ccgttcggtc aggggcgcgc agcgtgcgaa gcgctcgcag
    28861 tagaagccgc gcagggcctc cgccgcccgt tccgactgga acgcggcggc gatgaaggcg
    28921 gccggagccg ctgcggcggc cgggtcaccg aaggtgtcga cgatctcctg cgccagggcg
    28981 tgcagatcgc ctctgagggt gcccgtgtcg ggcggcgtcc acccgtcctc tcccgccagg
    29041 tccagcgcgt cggcgacgag cccttcgacg ccgccccagc ggcggtagag cgtcgtcttg
    29101 tggacgccgg actgctcggc cacgtactcc acggtgagcc ccggatagcc gtactcgacc
    29161 agcccggcga ggacggcgtc gcgtacggcc gcgcgggtgc gggcggtgcg gccgccgggt
    29221 cgcaccgtgc ccggcgcgga ggggggcggg gacgtggcgg gggagggcga cggcgaggag
    29281 ggaggcgtcg gagacaactg caactccagt tgcgttagct ggtggggtcg tgccatgctg
    29341 agcgtaacgc aactcgggtc gtgtttggtg tggcgcggtc gggggcgtgt tcccgggggc
    29401 ctcgcatgcc ccgagccgat gccgacggag gttcgcgcgt gcccactcag ctttctttgc
    29461 gcggtgtgtc catgtcccgg ggcgaccgcc cgctcctgga cgacgtcacg ttctcggtgc
    29521 ggccgggtga gcggatcggc atcgtcggcg agaacggtgc cgggaagtcc acgctgctca
    29581 ggctcctcgc cggcctcgag gcgcccgacg ccggtgcggt cgtcgccggt gcggagggcg
    29641 gcgtggcccg cctggggcag actcccgagc tgcctccgga ccgcacggtg ggcgacgccg
    29701 tcgacctggc tctggccgac ctccgcgcca tggagcgcag gctccgggag ctggaggccg
    29761 ctctggggga ggccgggccc gaagccctgg ccgagtacgg cgagctcctc accgcattcg
    29821 aggcgcgcgg cggctacgag gccgacgcca gggtggacaa ggcgctgcac gccctgggcc
    29881 ttgcccacat cggacgggag cggctgctgg gcagcctctc cggaggggaa caggcgcgcc
    29941 tcgggctcgc ctgcctcatc gcggcagccc ccgaggtcat gcttctggac gagcccacca
    30001 accatctgga cggcgcggcg ctggtctggc tcgaggacac cctgcgggcc caccccggca
    30061 ccgtcctcgc cgtctcccac gaccgcgtgt tcctcgaacg cgtcgccacc gccgtggtgg
    30121 agctcgacgc cgaccgcagg tccctcgtcc gctacggcgg ggggtacgcg gggttcatcg
    30181 aggagcaggc cgccgcccgc cgccgctggg agcaggcgta cgaggactgg tcggccgaga
    30241 cggcggcgct cgagggcacc gctgcgaccg tcgcccggcg cgtggccccc ggccgggccg
    30301 ccaaggacgg caacaagatg gcctacgacc gcgacaaggg ccgcgtccag gcctcggtct
    30361 ccagccgggt gcgcaacgcc caggagaggc tgcgccggct ccgggagaat ccggtgcccc
    30421 gcccgccgga gcccctgcgc ttcgacgccc gcccggcggc gggtacggcc gaaggcaccc
    30481 tcgtggccct ggaggacgta cgggtcgggg agcggctcgc gatcgcccgg atggaggtcc
    30541 gcgcgggtga gcggctgctg gtgcacgggg ccaacggtgc ggggaagagc accctgctcc
    30601 gtctgctcgc gggggtcacc gagccggacg ccggtaccgt cacccggcgg gggagcaccg
    30661 gctatctcgc ccaggagatc cccgtcaccc ggcccgcgga acggctgctc gccgccttcg
    30721 cccgcggcct ggccggcgcc gaggaggagc acagggccct gctgctgtcc tacgggctct
    30781 tccgggagcg tgacctccac gtgcccgtcg gcgccctctc ggcggggcag cgccgccgcc
    30841 tggggctcgc ccgcctcctc gcccggcccg ccgacctcct cctgctggac gagccgacga
    30901 accacctcgc cctaggcctg gtcgaacagc tggaagaggc ccttgccgcc tggtccggcg
    30961 ccctggtcgt ggtcacccac gaccggctcc tgcggcagcg cttcgagggc cggcagtgcg
    31021 agatacgggc cggccgggcg ctgatcgcgg ggtagcgagg cggccggtcg gtgctcgatc
    31081 tagggtggcg gcatgccacg gccccgacgc atcgttctca tccggcacgg agagtcggtg
    31141 ggcaatgtcg acgacacggt ctacgaacgg gagcccgacc acgccctcag tctgacggag
    31201 agaggccgca agcaggccag ggacgcaggg gctcccctcc gcgagctctt cggcgacgag
    31261 cgggtctcgg cctacgtctc gccctaccgg cgcacccacc agaccttcca cgccctgggg
    31321 ctggaccccg gcctcgtccg cgtccgcgag gaaccccggc tgcgcgagca ggactggggc
    31381 aactggcagg acctcgtcga cgtgcgccgg cagaaggcct accgggacgc ctacggccac
    31441 ttcttctacc gcttcgccca gggcgagtcc ggcgcggacg tctacgaccg tgtgggcgcc
    31501 ttcctggaga gtctgtggcg cagcttcgag gaccccgacc acccgcccaa cgtcctgctg
    31561 gtcacccacg gcctgaccat gcggctcttc tgcatgcggt ggttccactg gacggtcgcc
    31621 gagttcgagt gcctgtcgaa cccgggcaac gccgagaccc gtgccctgct cctcgggccc
    31681 gacggccggt accacctcga tcggcccttc gagcgctggt gcacccctga accgtacggc
    31741 ttcaccggtt agagttcgct ccgatgaccg ctgacagatt ccaccgcgca ctggcgagcc
    31801 tgcgcgggct ggccctcggc gacgccctcg gctcccagtt cttcgtcccg ggcaactacc
    31861 cgtcactcaa gcggcgcgag ctgcctccct ccccgtggca gtggaccgac gacaccgaga
    31921 tggcctgctc cgtgctggcc gtcctcgccg ggcacgggcg catcgaccag gacgcgctcg
    31981 cccgctcctt cgcggagcac cacgacttcg accggggata cggcccggcc gtgggccgca
    32041 tgctgcgcct ggtccgggag ggtggcgact ggcgcgagct ggcctcggcc ctcttcaacg
    32101 gacaggggtc ctggggcaac ggcgcggcga tgcgcatcgc cccgctcggc gcctggtacg
    32161 cggacgaccc ggaacaggcc acgcaccagg ccgagatctc cgcgtacacc acccaccagc
    32221 accgcgaggc ggtcgccggg acgatggccg tggccgccgc cgcggcgctg gccgccgctc
    32281 cggccggcct cccggccccc gacgccctcc tggagggagt cgtcgccctc gtgccgcgca
    32341 gcgccgtgca ggccgggctg cggcgcgcgc gggacatgct cgactacggc gacccgagca
    32401 cggtcgccgc cgtcctcggg tgcggccgcc gcaccagcgc gcacgacacc gtgccgttcg
    32461 ccctgtggtc cgcggcgcgc aacctcacgt cctacgaggc cgccttctgg accaccgcgc
    32521 aggtgggcgg cgacgtggac accaactgcg ccatcgtcgg cggagtggtc gccgcgggcg
    32581 agcggggcgc gccgcccgcc gactggctcc ggcgcaccga ggacctgccg gactggctcc
    32641 cgtccggcgt gggccggcgg taggagaaca ggccgcaaga accggaatgg aaccggccgt
    32701 aagaaagggg agggggcggg gctactcggg ccacccgtag gggcgtacgc ttgctggcgc
    32761 catgccgtac gaaccgccta cccacaccgt cgagcgctcc ctgcgcgcaa cgaccggagc
    32821 c
//
