LOCUS       NZ_BMUQ01000040        54214 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence40, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000040
VERSION     NZ_BMUQ01000040.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 54214)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 54214
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..54214
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /candidate_cluster_numbers="5"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            <1..4146
                     /locus_tag="IE289_RS48295"
     CDS             <1..4146
                     /NRPS_PKS="Domain: AMP-binding (136-537). E-value: 9.4e-98.
                     Score: 319.4. Matches aSDomain:
                     nrpspksdomains_IE289_RS48295_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (635-864). E-value: 3.7e-98. Score:
                     320.4. Matches aSDomain:
                     nrpspksdomains_IE289_RS48295_nMT.1"
                     /NRPS_PKS="Domain: PCP (1053-1119). E-value: 2.5e-25.
                     Score: 80.5. Matches aSDomain:
                     nrpspksdomains_IE289_RS48295_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1143-1361). E-value:
                     2.4e-37. Score: 121.5. Matches aSDomain:
                     nrpspksdomains_IE289_RS48295_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="IE289_RS48295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_190174501.1"
                     /sec_met_domain="AMP-binding (E-value: 9.2e-105, bitscore:
                     341.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-16, bitscore:
                     51.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 3.4e-34, bitscore:
                     110.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="PTRTTAHHPLFQISLAFQNNIYPTFALGDIKIDFEPISTGTAKFE
                     LLFNISELPRDGDHPLGYVGYVEYATDVFDRETIEQLITRFKTVLRTVVATPDTPLRAI
                     DVLLPDERHQLLGSSDPATEDAAIPEGSIPVLFEQQAARTPDAIAISSGGEDITYDELN
                     VRANQIAHELLAHGVHLESVVAVALPRSPELIAAILGILKAGAAYLPIDPAYPSLRNGS
                     ILADGQPALILTSSAVDTPDVLPVEGIPRLYVADIVGGERTNPSHDRLCPAHLAYVMFT
                     SGSAGRPKGVAVSHRSVLNDAWHGWPEGPGDRILVQSSIAFDASVYEIWPALLRGRTLV
                     PLPADRESPAQRLRFIAANEIDTLWATAGLFDLMSSEELDELSGLRTLRYLATGGDKVP
                     TAAVDRVLRANSAIRVINIYGPTETTVNATTHVVCAATRQRFDDPVVPIGVPIRNARVY
                     VLSAELDPVATGVVGELWIAGAGLARGYSGRPGPTAERFVPDPYGPAGSRMFRTGDLAR
                     WTREGVLVFVGRVDDQTKISGFRVEPGEIEAVLLAHPQVAQAAVVARDITGQGVKQLVA
                     YVVRNQVASADRQESREIELVDQWRDTYDDLYRGEHHAGDPADAGFGDDFRGWNSSYTE
                     TPIPLAEMREWRDATVARIRSLRPSKVLEIGVGTGLLLARLAPECETYYGTDFSESVID
                     GLRQHLAEVPADWADRVELVVQPADQVDLLPERDFDTIVLNSVVQYFPSVQYLVDVIEK
                     AMGLLAPGGALFIGDIRNKALLREFATTVQISRLGHQDAADLDEAEHGRIRSTIATAIA
                     METELVLHPDFFAALGDKLPAIGAVDVQVKRGWYDNELSQYRYDVTVRKAPVRAQSLAA
                     VPRLRWSEVGGLQELEQHLRTRRPETVRIVGVPHQALATAVRATGLLHAEHNAPAADGE
                     LREELYTLGERLGYSTAVTWSQVAGHLDVVLAAPGGGNTVRTDVYVPGFAQAGPLTVYG
                     NVPVADQAVDLRAFVSSQLPAYMVPSSVIFLDSLPLTANGKLKREALPAPEITGSSSRR
                     ARNAHEEVLTGLFSEVLGVPDVGIDDGFFELGGHSLLATRLLSRIRTVLRIDVPIRTVF
                     ECPTVADLAPRLLGMAPDGRDETYAPLMTIRSGGAERPLFCLHPVSGVGWFYLSLARYI
                     DDRPIYALQAPGLDPTGPDLMPTSMAQLVQTYLARIRSVQPHGPYNLLGWSFGGFAAHA
                     IAAELRARGEEVELLAMMDCYPDTAVEAGNLDGQEIREGFDQFLRHRYSDADSLDVDAI
                     SDLVTGISVEHIAMLTGYLPPEFDGAAVFFKAGAVTVDGEDSSRLDPAGAWRGHIHGPM
                     TVHVVPTSHQDMDRPESMQVVGNVLKQTFRNRTAGGDA"
     source          1..54214
                     /culture_collection="JCM:4551"
                     /db_xref="taxon:68239"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces mirabilis"
                     /strain="JCM 4551"
                     /submitter_seqid="sequence40"
                     /type_material="type strain of Streptomyces mirabilis"
     cand_cluster    1..54214
                     /SMILES="NC(CO)C(=O)NC(C)C(=O)NC(CS)C(=O)NC(C(C)C)C(=O)NC(C
                     C1=CNc2c1cccc2)C(=O)NC(C(C)C)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /protoclusters="4"
                     /tool="antismash"
     cand_cluster    1..33612
                     /SMILES="NC(CS)C(=O)NC(C(C)C)C(=O)NC(CC1=CNc2c1cccc2)C(=O)N
                     C(C(C)C)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33612
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[11842:13612](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(11843..13612)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..24146
                     /SMILES="NC(C(C)C)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..24146
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:4146](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      <1..4146
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     misc_feature    46..62
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.17"
                     /tool="antismash"
     misc_feature    157..159
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        412..1614
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48295_AMP-binding.1"
                     /evalue="9.40E-98"
                     /label="IE289_RS48295_AMP-binding.1"
                     /locus_tag="IE289_RS48295"
                     /protein_end="537"
                     /protein_start="136"
                     /score="319.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEQQAARTPDAIAISSGGEDITYDELNVRANQIAHELLAHGVHLE
                     SVVAVALPRSPELIAAILGILKAGAAYLPIDPAYPSLRNGSILADGQPALILTSSAVDT
                     PDVLPVEGIPRLYVADIVGGERTNPSHDRLCPAHLAYVMFTSGSAGRPKGVAVSHRSVL
                     NDAWHGWPEGPGDRILVQSSIAFDASVYEIWPALLRGRTLVPLPADRESPAQRLRFIAA
                     NEIDTLWATAGLFDLMSSEELDELSGLRTLRYLATGGDKVPTAAVDRVLRANSAIRVIN
                     IYGPTETTVNATTHVVCAATRQRFDDPVVPIGVPIRNARVYVLSAELDPVATGVVGELW
                     IAGAGLARGYSGRPGPTAERFVPDPYGPAGSRMFRTGDLARWTREGVLVFVGRVDDQTK
                     IS"
     aSModule        412..4086
                     /complete
                     /domains="nrpspksdomains_IE289_RS48295_AMP-binding.1"
                     /domains="nrpspksdomains_IE289_RS48295_nMT.1"
                     /domains="nrpspksdomains_IE289_RS48295_PCP.1"
                     /domains="nrpspksdomains_IE289_RS48295_Thioesterase.1"
                     /final_module
                     /locus_tags="IE289_RS48295"
                     /monomer_pairings="X -> NMe-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       598..639
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48295"
                     /protein_end="212"
                     /protein_start="198"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LGILKAGAAYLPID"
     CDS_motif       829..888
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0002"
                     /evalue="3.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="IE289_RS48295"
                     /protein_end="295"
                     /protein_start="275"
                     /score="28.7"
                     /tool="antismash"
                     /translation="AYVMFTSGSAGRPKGVAVSH"
     CDS_motif       1411..1494
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0003"
                     /evalue="1.10E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="IE289_RS48295"
                     /protein_end="497"
                     /protein_start="469"
                     /score="46.5"
                     /tool="antismash"
                     /translation="GVVGELWIAGAGLARGYSGRPGPTAERF"
     CDS_motif       1579..1644
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0004"
                     /evalue="9.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE289_RS48295"
                     /protein_end="547"
                     /protein_start="525"
                     /score="33.8"
                     /tool="antismash"
                     /translation="FVGRVDDQTKISGFRVEPGEIE"
     aSDomain        1909..2595
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48295_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="3.70E-98"
                     /label="IE289_RS48295_nMT.1"
                     /locus_tag="IE289_RS48295"
                     /protein_end="864"
                     /protein_start="635"
                     /score="320.4"
                     /tool="antismash"
                     /translation="TPIPLAEMREWRDATVARIRSLRPSKVLEIGVGTGLLLARLAPEC
                     ETYYGTDFSESVIDGLRQHLAEVPADWADRVELVVQPADQVDLLPERDFDTIVLNSVVQ
                     YFPSVQYLVDVIEKAMGLLAPGGALFIGDIRNKALLREFATTVQISRLGHQDAADLDEA
                     EHGRIRSTIATAIAMETELVLHPDFFAALGDKLPAIGAVDVQVKRGWYDNELSQYRYDV
                     TVRKAPV"
     CDS_motif       2506..2553
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0005"
                     /evalue="2.70E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="IE289_RS48295"
                     /protein_end="850"
                     /protein_start="834"
                     /score="-1.8"
                     /tool="antismash"
                     /translation="GAVDVQVKRGWYDNEL"
     CDS_motif       2881..2904
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0006"
                     /evalue="9.90E+01"
                     /label="NRPS-beforete1"
                     /locus_tag="IE289_RS48295"
                     /protein_end="967"
                     /protein_start="959"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="VLAAPGGG"
     aSDomain        3163..3360
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48295_PCP.1"
                     /evalue="2.50E-25"
                     /label="IE289_RS48295_PCP.1"
                     /locus_tag="IE289_RS48295"
                     /protein_end="1119"
                     /protein_start="1053"
                     /score="80.5"
                     /tool="antismash"
                     /translation="EEVLTGLFSEVLGVPDVGIDDGFFELGGHSLLATRLLSRIRTVLR
                     IDVPIRTVFECPTVADLAPRL"
     aSDomain        3433..4086
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48295_Thioesterase.1"
                     /evalue="2.40E-37"
                     /label="IE289_RS48295_Thioesterase.1"
                     /locus_tag="IE289_RS48295"
                     /protein_end="1361"
                     /protein_start="1143"
                     /score="121.5"
                     /tool="antismash"
                     /translation="RPLFCLHPVSGVGWFYLSLARYIDDRPIYALQAPGLDPTGPDLMP
                     TSMAQLVQTYLARIRSVQPHGPYNLLGWSFGGFAAHAIAAELRARGEEVELLAMMDCYP
                     DTAVEAGNLDGQEIREGFDQFLRHRYSDADSLDVDAISDLVTGISVEHIAMLTGYLPPE
                     FDGAAVFFKAGAVTVDGEDSSRLDPAGAWRGHIHGPMTVHVVPTSHQDMDRPESM"
     CDS_motif       3436..3465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0007"
                     /evalue="5.90E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="IE289_RS48295"
                     /protein_end="1154"
                     /protein_start="1144"
                     /score="9.7"
                     /tool="antismash"
                     /translation="PLFCLHPVSG"
     CDS_motif       3619..3693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0008"
                     /evalue="1.90E-13"
                     /label="NRPS-te1"
                     /locus_tag="IE289_RS48295"
                     /protein_end="1230"
                     /protein_start="1205"
                     /score="42.6"
                     /tool="antismash"
                     /translation="QPHGPYNLLGWSFGGFAAHAIAAEL"
     CDS_motif       3943..3966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48295_0009"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48295"
                     /protein_end="1321"
                     /protein_start="1313"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="FKAGAVTV"
     gene            4143..4889
                     /locus_tag="IE289_RS48300"
                     /old_locus_tag="GCM10010317_099320"
     CDS             4143..4889
                     /NRPS_PKS="Domain: Thioesterase (23-181). E-value: 2.9e-17.
                     Score: 55.8. Matches aSDomain:
                     nrpspksdomains_IE289_RS48300_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.5"
                     /locus_tag="IE289_RS48300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099320"
                     /product="thioesterase II family protein"
                     /protein_id="WP_229889616.1"
                     /sec_met_domain="Thioesterase (E-value: 1e-17, bitscore:
                     56.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGKEQNHNRWFATVPPDDCDHLLLCFPYSGCGASMYRLWPNRIG
                     DTAVVPLQLPGRETRMGEAHYGTYENLAEQMTAELGPVLDRDFSVFGHCGAALAAFEFA
                     RRMASGDTRSPTTCFVSSQVAPDDGPYGRFLDMSEDELRVVVVNLLGLVTPTKRLVDFF
                     VKVLVDDLAANKVYRPDRSTTDSFEIRAIGWSADVEIPHGLMAGWARWGRCTSLVLDGD
                     HQAFVKAPGHLLDALQAGVEADTRAL"
     aSDomain        4212..4685
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48300_Thioesterase.1"
                     /evalue="2.90E-17"
                     /label="IE289_RS48300_Thioesterase.1"
                     /locus_tag="IE289_RS48300"
                     /protein_end="181"
                     /protein_start="23"
                     /score="55.8"
                     /tool="antismash"
                     /translation="LLCFPYSGCGASMYRLWPNRIGDTAVVPLQLPGRETRMGEAHYGT
                     YENLAEQMTAELGPVLDRDFSVFGHCGAALAAFEFARRMASGDTRSPTTCFVSSQVAPD
                     DGPYGRFLDMSEDELRVVVVNLLGLVTPTKRLVDFFVKVLVDDLAANKVYRPDR"
     gene            4891..5640
                     /locus_tag="IE289_RS48305"
                     /old_locus_tag="GCM10010317_099330"
     CDS             4891..5640
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS48305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_099330"
                     /product="hypothetical protein"
                     /protein_id="WP_229889617.1"
                     /transl_table=11
                     /translation="MADRTVRIPARYNGPPGTANGGYACGTFAKPAADHQRPPVAVALL
                     VAPRLDHALEFRPGSRRSQIWDGDRLIATTTTASAEFPAVEAVSLQAAADASGRYRGRV
                     GHPFPTCFVCGVDREPADGFPVAPGEVPGAPGIVACPWTPTAAASDRPELVWSVLDCPG
                     GWTTDPVWEPMVLTRMTAVLRRPPRPLAPHVVVARRWRRQGRTASVGTALYDDRGELVA
                     KATAMWTAVGVQEPADGREQGDLDEDE"
     cand_cluster    5174..46934
                     /SMILES="NC(CO)C(=O)NC(C)C(=O)NC(CS)C(=O)NC(C(C)C)C(=O)NC(C
                     C1=CNc2c1cccc2)C(=O)NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="4"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    5174..46934
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[25173:26934](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      25174..26934
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="3"
     gene            5633..6862
                     /locus_tag="IE289_RS48310"
                     /old_locus_tag="GCM10010317_099340"
     CDS             5633..6862
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670468.1"
                     /locus_tag="IE289_RS48310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099340"
                     /product="cytochrome P450"
                     /protein_id="WP_190174502.1"
                     /sec_met_domain="p450 (E-value: 5.4e-21, bitscore: 65.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSERTAPAASTDLDSLDLMDPRLYGSGDPHTIWTALRERAPLHLQ
                     SLPDGRRFWSVTKYHDVREVLRDHTRFTSSRGTLLSVLGSRDPAGGKMMAASDPPVHTM
                     LHEPIAKLLSRRALEPFVPEVRRVAHRLLERLADGPRDLAELAAGFPMAFTGTLMGIPE
                     QDWARLTVLTTAAIAPEDPDFRLGNGLNTLATAHHELFSYFSRRTRRTTREDGLIGALL
                     GLEVGGRRLRHDELVYNCYSLLLGANVTTPHAVTQTVLAFIENPAEYRRLVDDPRLVPG
                     AVEEGLRWSSPASHFLRHATQDTTLRGRQVREGDAVVTWLGSANRDEEVFSEPFRFHVT
                     RSPNPHVAFGFGPHHCVGAALARMALNALFAEIAGSVERFDLAGPVEHLASNFAAGIKH
                     MPVVTKLRTT"
     gene            complement(6903..8096)
                     /gene="kynU"
                     /locus_tag="IE289_RS48315"
                     /old_locus_tag="GCM10010317_099350"
     CDS             complement(6903..8096)
                     /EC_number="3.7.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0030429 - kynureninase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006569 - tryptophan catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (80-362). E-value: 1.6e-22.
                     Score: 71.8. Matches aSDomain:
                     nrpspksdomains_IE289_RS48315_Aminotran_5.1"
                     /codon_start=1
                     /gene="kynU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132218.1"
                     /locus_tag="IE289_RS48315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099350"
                     /product="kynureninase"
                     /protein_id="WP_190174503.1"
                     /sec_met_domain="Aminotran_5 (E-value: 7.6e-19, bitscore:
                     58.8, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTPSRETAERLDRTDPLAAVRTRYSLPEGVVYLDGNSLGALSVG
                     VPAAVQTAVVENWGRHLINVWTDDGWWDAPLRVGDRVGRLLGARAGQTVVGDSTSVHLF
                     NVLTAAARLRPDRRLLLVEEGGFPTNHYLATSVARILGLEVRRVPMPDMASTLRRLGER
                     VAVATAGAVDFRTGELWDVRAVTDAAHDVGALVVWDLCHAVGALPLTLDADGVDFAVGC
                     SYKFLSGGPGAPGFVYAASRHHGDIDQPLCGWHGHAEPFAMVLDYEPTTGIGRLRVGSP
                     NILSMLALDAALDVFDDVEMAAVREKNVALGNFFIEAVDAHLAGRGFELVTPRRGDQRG
                     SQVTLCHPEAERIMRALNKHGIIGDARPPELLRFGFNSLYISYTDIFAVVEALRSCT"
     aSDomain        complement(7011..7856)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48315_Aminotran_5.1"
                     /evalue="1.60E-22"
                     /label="IE289_RS48315_Aminotran_5.1"
                     /locus_tag="IE289_RS48315"
                     /protein_end="362"
                     /protein_start="80"
                     /score="71.8"
                     /tool="antismash"
                     /translation="RVGRLLGARAGQTVVGDSTSVHLFNVLTAAARLRPDRRLLLVEEG
                     GFPTNHYLATSVARILGLEVRRVPMPDMASTLRRLGERVAVATAGAVDFRTGELWDVRA
                     VTDAAHDVGALVVWDLCHAVGALPLTLDADGVDFAVGCSYKFLSGGPGAPGFVYAASRH
                     HGDIDQPLCGWHGHAEPFAMVLDYEPTTGIGRLRVGSPNILSMLALDAALDVFDDVEMA
                     AVREKNVALGNFFIEAVDAHLAGRGFELVTPRRGDQRGSQVTLCHPEAERIMRALNKHG
                     I"
     gene            complement(8170..9762)
                     /locus_tag="IE289_RS48320"
                     /old_locus_tag="GCM10010317_099360"
     CDS             complement(8170..9762)
                     /EC_number="1.14.19.-"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     flavin-dependent trp 6 7 halogenase"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000029: Halogenation (68% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640522.1"
                     /locus_tag="IE289_RS48320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099360"
                     /product="tryptophan halogenase family protein"
                     /protein_id="WP_190174504.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.4e-168,
                     bitscore: 552.3, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNLIKKILVLGGGTAGWMTASYLGKALGSTVRITVLEAPAIPK
                     IGVGEATIPNLQRVFFDYLGLTEEEWMPECNASYKMGIRFINWRTPGTGTARPRPYGQY
                     GDQFDHLFGLLPNHDNLPLSHYWTYQKLNGMTDEPFDRACYPQPALFDRKLSPRFPDGR
                     RVASYAWHFDADLVADFLRRFATARQGATHIEDKFIAAETDQRGHLVAVTTESGRRLEA
                     DLFIDCSGFRSLLINQVMKEPFLDMSDHLLNDRAVATRLEHDDEEHGVEPYTSAIAMSS
                     GWAWKIPMLGRFGTGYVYSSRFTSQEEATREFCQMWGISPDTHPMNHVRFRVGRNRRAW
                     VKNCVGIGLSSCFLEPLESTGIYFTYAALYQLVKHFPDKRFDPMLTKSFNSEIEAMFDD
                     TRDFIQGHFSFAPRDDTPFWRACKELELAPEFVRKVEMYKAGLGVDLPVTDESTYYGNF
                     EAEFRNFWSNANYYCVFAGLGMMPEHDPTPLDYRPESVKSAEAVFAQVQRRRDELLDTL
                     PPMHTYLRRLHGK"
     gene            complement(9759..10688)
                     /locus_tag="IE289_RS48325"
                     /old_locus_tag="GCM10010317_099370"
     CDS             complement(9759..10688)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384935.1"
                     /locus_tag="IE289_RS48325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099370"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_190174505.1"
                     /transl_table=11
                     /translation="MSFLVYGRYNQTELDRQYSPSSCVDDLSAFLTSYTTRSARTRTEL
                     PVNAGIPYGSLPCESLDFFPARGPQAPLLVFVHGGYWRELGKDDSSFPARRLVPAGIAF
                     AAIGYGLAPRYRLDEIVDQVRRAVWWLVEHAGDLGVDSERIVLAGSSAGAHLALMALLD
                     GWMPEGTRPADVIAGAVLLSGVYDLEPIRLTYVNEPLGLDAEAAARLSPIRRLPDRLPP
                     LVVARGGAETAEFARQHRELVEAATPRSAAVRDLVIPHRNHFDITFDLDDPASDLGAAV
                     LRQLGLPGRASSRTAGDSVRSHRDIGRT"
     cand_cluster    10334..54214
                     /SMILES="NC(CO)C(=O)NC(C)C(=O)NC(CS)C(=O)NC(C(C)C)C(=O)NC(C
                     C1=CNc2c1cccc2)C(=O)NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="5"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="4"
                     /tool="antismash"
     protocluster    10334..54214
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[30333:47612](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="4"
                     /tool="antismash"
     proto_core      complement(30334..47612)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="4"
     gene            complement(10720..11625)
                     /locus_tag="IE289_RS48330"
                     /old_locus_tag="GCM10010317_099380"
     CDS             complement(10720..11625)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172812.1"
                     /locus_tag="IE289_RS48330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099380"
                     /product="tryptophan 2,3-dioxygenase"
                     /protein_id="WP_190174506.1"
                     /transl_table=11
                     /translation="MELERTAPLSYTPLTEEERRRRAESTGGEPMLDFDVTNGSESTAY
                     IGYHHVDVLLGLQHPRTSEPAELSFYITGQIQELLFKLLFTEVNRIRDLLFADDLDEAL
                     RYLRRAGHVQRVLTTTWEPVSTITPAEFAAFRDELGSASGIQSYMYRQLEFALGNKAPR
                     MVEPYRPVGWVYEQVMAALRAPSLYDAALGVLRRRGLGVPAHCVERDFAEPYQPHAAVE
                     QAWARVYRSHREHPDVHALAEALCDLNHQHAQWRYTHLLTVERILGHKPGTGGTSGVSW
                     LHKVAEHRFFPELLGARTAI"
     misc_feature    11704..11715
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(11761..11776)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.52"
                     /tool="antismash"
     gene            complement(11843..13612)
                     /locus_tag="IE289_RS48335"
                     /old_locus_tag="GCM10010317_099390"
     CDS             complement(11843..13612)
                     /NRPS_PKS="Domain: AMP-binding (11-409). E-value: 8.2e-98.
                     Score: 319.6. Matches aSDomain:
                     nrpspksdomains_IE289_RS48335_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (518-583). E-value: 1.6e-21.
                     Score: 68.4. Matches aSDomain:
                     nrpspksdomains_IE289_RS48335_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="IE289_RS48335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099390"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_190174507.1"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-102, bitscore:
                     333.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-21, bitscore:
                     67.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTAASVVEVFEQQAAKRPEAIAVRGAGGELTYAELDRRANQLA
                     HELRARGVDVEVPVALLMRRSTDLIVTLVAVLKAGGVYLALDHRLPAERRATVLLDARP
                     ALVITDEGEPSATDGGPPWCPLPELSACASRRPTTRPVTRTSPESTAYIAYTSGSAGKP
                     KGVMVPHRAIERLVVGAGYLPIGPDDVFLQLAPIAFDASTLEIWGPLLNGGKLVVAPEE
                     QLPLGALADLVRGEGVTILWLTAGLFHHLVASGLVARLRGLRFLLAGGDVLSVESVNAA
                     MAELAGTTLINGYGPTENTTFTCCAPLAEPVTAPRVPIGPAIDGTSVYVLDDAVGTAPD
                     GQAGRIHAAGAGLARGYLNDPALTAQRFVANPFSRVPGDRMYRTGDLGSRGEDGALDFH
                     GREDRQVKIRGFRIEPGDVEHALRVHPDVADAAIVATSSGDERSLVGFYVADEPLVSEH
                     LRKHMETLVPPYMIPAVLVWLEALPLTVNGKVDRDALTAYAPPGRGDLSSDYRGPGNPL
                     EQWLAEMWGDLTQTSPVGVDDDFFELGGHSLMAVRIIVEISDRTGVEIDPQDFYACPTI
                     SELAGLIAAGAPE"
     aSDomain        complement(11864..12058)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48335_PP-binding.1"
                     /evalue="1.60E-21"
                     /label="IE289_RS48335_PP-binding.1"
                     /locus_tag="IE289_RS48335"
                     /protein_end="583"
                     /protein_start="518"
                     /score="68.4"
                     /tool="antismash"
                     /translation="QWLAEMWGDLTQTSPVGVDDDFFELGGHSLMAVRIIVEISDRTGV
                     EIDPQDFYACPTISELAGLI"
     aSModule        complement(11864..13579)
                     /complete
                     /domains="nrpspksdomains_IE289_RS48335_AMP-binding.1"
                     /domains="nrpspksdomains_IE289_RS48335_PP-binding.1"
                     /locus_tags="IE289_RS48335"
                     /monomer_pairings="Val -> Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(12356..12421)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48335_0005"
                     /evalue="2.90E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE289_RS48335"
                     /protein_end="419"
                     /protein_start="397"
                     /score="35.3"
                     /tool="antismash"
                     /translation="FHGREDRQVKIRGFRIEPGDVE"
     aSDomain        complement(12386..13579)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48335_AMP-binding.1"
                     /evalue="8.20E-98"
                     /label="IE289_RS48335_AMP-binding.1"
                     /locus_tag="IE289_RS48335"
                     /protein_end="409"
                     /protein_start="11"
                     /score="319.6"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEQQAAKRPEAIAVRGAGGELTYAELDRRANQLAHELRARGVDVE
                     VPVALLMRRSTDLIVTLVAVLKAGGVYLALDHRLPAERRATVLLDARPALVITDEGEPS
                     ATDGGPPWCPLPELSACASRRPTTRPVTRTSPESTAYIAYTSGSAGKPKGVMVPHRAIE
                     RLVVGAGYLPIGPDDVFLQLAPIAFDASTLEIWGPLLNGGKLVVAPEEQLPLGALADLV
                     RGEGVTILWLTAGLFHHLVASGLVARLRGLRFLLAGGDVLSVESVNAAMAELAGTTLIN
                     GYGPTENTTFTCCAPLAEPVTAPRVPIGPAIDGTSVYVLDDAVGTAPDGQAGRIHAAGA
                     GLARGYLNDPALTAQRFVANPFSRVPGDRMYRTGDLGSRGEDGALDFHGREDRQVKIR"
     CDS_motif       complement(12509..12598)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48335_0004"
                     /evalue="2.70E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="IE289_RS48335"
                     /protein_end="368"
                     /protein_start="338"
                     /score="45.3"
                     /tool="antismash"
                     /translation="PDGQAGRIHAAGAGLARGYLNDPALTAQRF"
     CDS_motif       complement(13058..13081)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48335_0003"
                     /evalue="7.70E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48335"
                     /protein_end="185"
                     /protein_start="177"
                     /score="1.0"
                     /tool="antismash"
                     /translation="VGAGYLPI"
     CDS_motif       complement(13103..13162)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48335_0002"
                     /evalue="2.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="IE289_RS48335"
                     /protein_end="170"
                     /protein_start="150"
                     /score="29.4"
                     /tool="antismash"
                     /translation="AYIAYTSGSAGKPKGVMVPH"
     CDS_motif       complement(13352..13390)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48335_0001"
                     /evalue="1.40E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48335"
                     /protein_end="87"
                     /protein_start="74"
                     /score="12.2"
                     /tool="antismash"
                     /translation="AVLKAGGVYLALD"
     gene            complement(13740..15125)
                     /locus_tag="IE289_RS48340"
                     /old_locus_tag="GCM10010317_099400"
     CDS             complement(13740..15125)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020549841.1"
                     /locus_tag="IE289_RS48340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099400"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_190174508.1"
                     /transl_table=11
                     /translation="MSADVETLAAEVRGPVLLPGSRGYDEERTGFQTGFRHRPAVVVGA
                     TRPEDVRAAVRFAAERRLPVAVQSTGHGIVTALDGEGVLITTRRMKAVVVDAEGGTVRA
                     QAGVLWGEVIERAAPYGLAPVNGSAPHIGVVGYLLGGGVGLLGRRTGYASDYVRAIDIV
                     TADGALRHVTAGSDTDLFWALRGGGGNFGAVTAIETALVPVTRLYGGGLHFAADHPVDL
                     LHAYRAWTLTLPEELTSSIGLMTFPPLPSVPEPLRGRYVAHVRIAFTGSAEEGERLVAP
                     LRALGPRLIDTVREMPYTEVGTIYQDPHVPHAYFGGNVLLSELDPTALRTVVEVAGPDA
                     TVPCIVDIRHLGGAFGRRPTDPGVVGGRDAAYMLRVMTGGTAAPSTAARPVHQRVYDAL
                     KQWTVGRSLNSVYNDGAPVRQEQVRELFAAEDFERLRRVKTLHDPHNLFRFNHNIRPTA
                     ATD"
     gene            complement(15191..16573)
                     /locus_tag="IE289_RS48345"
                     /old_locus_tag="GCM10010317_099410"
     CDS             complement(15191..16573)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS48345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_099410"
                     /product="DoxX family protein"
                     /protein_id="WP_190174509.1"
                     /transl_table=11
                     /translation="MKVRVGKWLRTVASSPAGRAARRVVPSAGASPAPPPWTGAARAAY
                     RFGFAYAGLYCLTSPQVYLALRGGGMGRLQEAADSWAKLWEVRPVRNWMSVRVLGRELG
                     DRFDGGDDPHTWAGQLCWLAGAAAATPVWSVLDRNRTDYAALDKWVRLAARFCLAGQMF
                     SYGAAKAVPLQFQLPPSKLVEPLGDLSPMGLLWAQTGSSKPYQMLLGCAEIAGGLLLIV
                     PRTASLGALVSAAEMAQVLLLNMTFDVPVKVHSFHLLLLSLLLLAPHTPRLAEALLTER
                     PVPAAAPADLFRSRRANRIATALQAGAGLWLLGAQLRNDWSFWKNHGGGREKPELYGVW
                     DVTDFSIDGERHPPMTTDGQRWRRVVVDSVDAVAIQHMDDSLDPCMAAIDMNARSVALT
                     KMADPKWQVTFTFERPADDRLILEGDADGYHLRLHLRRRDLGTFPLVGRGFHWVQDNSY
                     LR"
     gene            complement(16614..17327)
                     /locus_tag="IE289_RS48350"
                     /old_locus_tag="GCM10010317_099420"
     CDS             complement(16614..17327)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="IE289_RS48350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099420"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_190174510.1"
                     /transl_table=11
                     /translation="MTEPVAAPDGPAPMTEVFDAVYRGESPFGKRPPWDIGAPQPAYVA
                     LEEAGLIGGAVLDAGCGTGEDALHLAGKGYAVTGLDLSPTAISLARDKAGARGLDAVFE
                     VADALDLKGWEGRFDTVIDSGLAHTFEGDTLRSYAAALHRACRPGAVAHILSISDRGSA
                     EMQARLAEAIEEIPAPLPDNDEPPGLKRSADHLRHGFADGWTVESIDETHIRGIIPTTS
                     ELLDVHAWLGRFRRS"
     gene            complement(17405..18223)
                     /locus_tag="IE289_RS48355"
                     /old_locus_tag="GCM10010317_099430"
     CDS             complement(17405..18223)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.5"
                     /locus_tag="IE289_RS48355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099430"
                     /product="ABC transporter permease"
                     /protein_id="WP_190174511.1"
                     /transl_table=11
                     /translation="MTSTTLTRESGTSYTQSRNTLGWWLSDVWQMTLRNVRHVLRSPDL
                     VMFSLVQPVMFILLFTYVFGGAMDVGGERYAQFLLPGVLVQMALYGSAAGTTIGVAAEM
                     REGLMDRFRSMPMSRTAVLIGRTLSEIFRNVGVACVTVGVGVLVGFRFHNGLLPALAGL
                     LLLLLFGYAVSWFAAYLGLSVRNAEAAQAVGGVWIFPFTLISSAFVPTDTMPGWLQAYA
                     AHSPMTAAVNALRALFTGGPATSYVLQTVAWSVGLIAVFAPLAVRKYGSR"
     gene            complement(18220..19203)
                     /locus_tag="IE289_RS48360"
                     /old_locus_tag="GCM10010317_099440"
     CDS             complement(18220..19203)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014144558.1"
                     /locus_tag="IE289_RS48360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099440"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_190174512.1"
                     /transl_table=11
                     /translation="MPAAIRTAGLCKRFGSLTALDHLDLTVSEGTVHGLLGPNGAGKTT
                     TVRVLATLIRPDEGAAEVFGVDVRDDPGRIRSVIGLTGQYAAVDELLTGRENLHMIGRL
                     FRLSKSDCRARASELLERFGLDDAADRQPRTYSGGMRRRLDVAASLMARPRLIFLDEPT
                     TGLDPRSRMEVWRLVRELVAEGTTVLLTTQYLEEADQLADSLSVIDRGRVIAGGTPDEL
                     KAQVGQDRVGITLLDGEGMEQTVRLLRERLGADPVADPQKMVVHAPLPDGGTLPDLLHL
                     LRESGIAIGDVALRRPTLDDVFLAVTGRSADHGVDQRNIGKETGRT"
     gene            complement(19266..20204)
                     /locus_tag="IE289_RS48365"
                     /old_locus_tag="GCM10010317_099450"
     CDS             complement(19266..20204)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019604.5"
                     /locus_tag="IE289_RS48365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099450"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_190174513.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.3e-13, bitscore:
                     41.0, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 2.4e-09, bitscore: 28.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSHADHTTVIVGAGPAGLTAALSLARYRHPVTVVDSPRAPRNSA
                     SAGVHGHVGMDGVTPGEFRARAWRELSRYATVERLEADAESVTPAPGGGFRVAVGGGET
                     VEARTVLLATGVVDVHPADVDGFAECWGRSVIHCPFCLGEENAGGRWATVADNAELAGL
                     SAVAFLAWSEDTIAICQESMPGLETARATARSSGGEVVTGTVRRLHHRQGALYAVELDD
                     GRVLERETLVWTPRQRQQPVVRRTAEELKLTVDDAGFIGVDASQCTSVPGLYAAGDLTS
                     RWKQSVTVSAAAGAAAADAIHMSALLGAVRR"
     gene            complement(20503..22881)
                     /locus_tag="IE289_RS48370"
                     /old_locus_tag="GCM10010317_099460"
     CDS             complement(20503..22881)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891653.1"
                     /locus_tag="IE289_RS48370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099460"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_190174514.1"
                     /transl_table=11
                     /translation="MTAGKETDTQPPGLCAADGHDLIRVHGARENNLKNVHVEIPKRRL
                     TVFTGVSGSGKSSLVFDTIAAESQRLINETYSAFIQGFMPTLARPEVDVLDGLTTAILV
                     DQQPMGSSLRSTVGTATDAGTLLRILFSRLAKPHIGSQKAFAFNVASADASGVLVVNGK
                     KIEKGFSVVGGMCLRCEGMGTVSDIDPAQLLDDSKSLADGAVTVPGWKPDGWVVQSFTE
                     SGFLDPHKAIRDYTEQERYDFLHRDPVKVKVKGVNTTYEGLLARVRKSFLSKDKETLQP
                     HIRAFVERAVAFSVCPECHGTRLSETARSAKIDGLSIADACAMQISDLAAWARGLTDPS
                     VTTLLTVLGQTLDSFVQIGLGYLSLDRSSGTLSGGEAQRVKMVRHLGSALTDVTYVFDE
                     PTVGLHPHDIQRMNDLLLRLRDKGNTVLVVEHKPETIVIADHVVDLGPHAGTKGGEVVF
                     EGTVEGLRASGTVTGRHLDDRASLKPSVRERSGVLEVRGANAHNLRDVDVDIPLGVLTV
                     LTGVAGSGKSSLIHGSVAGRDGVVTVDQSPIKGSRRSNPATYTGMLEPIRKTFAKVNGV
                     KPALFSPNSEGACPTCKGAGVIYTDLAIMAGVATTCEECEGKRFQASVLQYRLGGRDIS
                     EVFAMPVAEAAEFFRSGEARTPAAYAVLDRLAEVGLGYLSLGQPLTTLSGGERQRLKLA
                     GHMAGTGSVYILDEPTSGLHLADVEQLLALLDRLVDAGKTVIVVEHHQAVMAHADWIID
                     LGPGAGHDGGKIVFEGTPAELVADRPTLTGEHLAQYVGA"
     misc_feature    23020..23036
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.12"
                     /tool="antismash"
     misc_feature    complement(23020..23036)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.54"
                     /tool="antismash"
     gene            23040..23813
                     /locus_tag="IE289_RS48375"
                     /old_locus_tag="GCM10010317_099470"
     CDS             23040..23813
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510240.1"
                     /locus_tag="IE289_RS48375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099470"
                     /product="TioE family transcriptional regulator"
                     /protein_id="WP_190174515.1"
                     /transl_table=11
                     /translation="MKHLRPFDLAREHGISTQAVRNYERDGFIPLAQRTPSGYRTYTET
                     HAAALRAYLALVQAYGYATGGEIMRSLNTGDLDAALTAVDRGHAQLLRDRSTLDAVGRA
                     VEHLTSAPGLAEHTSAGSEPLSIGELARRLGVTAATLRNWEAVGILTPAREPVTGHRSF
                     DATDVRDAELTHLLRRGGYPLEHIRTVVRQIRTAGGTEALSAALDDWRRRLTARGVSML
                     GAAAQLGGYMAHSGVPAGPPATTEPAPAPGPPPTV"
     misc_feature    complement(23877..23890)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.12"
                     /tool="antismash"
     gene            23900..25084
                     /locus_tag="IE289_RS48380"
                     /old_locus_tag="GCM10010317_099480"
     CDS             23900..25084
                     /GO_function="GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009338840.1"
                     /locus_tag="IE289_RS48380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099480"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_308435138.1"
                     /transl_table=11
                     /translation="MSKDFHDLPVASCAVLALGEPTHREPAFGWVRNELFARLAEIGFR
                     SIALETDRVAALRVDDFVKGGDGDLDEVAREGFSHDFGNLETNRCLVAWMRDHNASRPP
                     EERLSFHGFDVPTETTSAPSPRRCLEFARDYLRLDLDLAGLLGADEQWSRAEAVMDPAM
                     SVGATPEAERLWSLADDMLTLLHSNAAERIAQTSRAEWLRARAHLTAGLGLLRYHRQAA
                     QRLENNDRLSRLFATRDALMAQNLLDIRSIEGRRGASLVFAHNVHLQRTPSTWSLGDLS
                     VNWPGAGTVVAPLLGEQYVFIVGSLGRSEAVGLGDPEPGTYESRLQDRVTDWAMAPTGK
                     VAAARTRTDTTPQQGYFPLDRATLDTADAVLHVSDGAAVSRDLLRVPAGAGSGY"
     gene            25174..26934
                     /locus_tag="IE289_RS48385"
                     /old_locus_tag="GCM10010317_099490"
     CDS             25174..26934
                     /NRPS_PKS="Domain: AMP-binding (7-403). E-value: 3.9e-98.
                     Score: 320.7. Matches aSDomain:
                     nrpspksdomains_IE289_RS48385_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (516-582). E-value: 5.1e-23. Score:
                     73.1. Matches aSDomain: nrpspksdomains_IE289_RS48385_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962805.1"
                     /locus_tag="IE289_RS48385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099490"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_190174517.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-105, bitscore:
                     344.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-17, bitscore:
                     54.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTVPALFESTVARRGGEPALIDGESTLGYAELNTRINRLARRLI
                     AHGVGPDSLVAVAMPKSSELIVAIMAVLKAGGAYLPLDPGYPAERLRFMLADARPVLLL
                     RSSSVAPLGAGPEELVLDDPAFRAACAALPGHDVAQHERRAVLRPEHLMYVIYTSGSTG
                     TPKGVAVPHSGVRDMAATQAAVLRAGPGDRVLQWASISFDAAFWDVSLALLSGAALVMV
                     SADDLLPGQPLWNTLFKYGITHAVLPPVALSETDAEDILLGGTVMSTGDSCTPTLVRKW
                     SRARRMFNGYGPTEVTVGATIGGPVRDAGDVGIGMPWIGNEVHVLDESLRPVPPGTEGE
                     LYIAGSGLARGYLNRFGATAVKFVADPFGPPGSRMYRTGDRGRRGPDGELFFAGRADGQ
                     VKLRGFRVELGEIETRLAAHPAVDVAVAVVRGELAEAHVVGYVTTTAPVEPDDLRAHVA
                     ESLPAHMVPARVTVLERFPTLANGKIDRGALPQPDAGAEGFPDGGRAPDAAEADGCAAV
                     VCAIVRDILGVPEARLSDNFFQLGGHSVQATRLAARIRERFEVALSIRTVLEAATIGEL
                     AAAVESRLSG"
     aSDomain        25195..26382
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48385_AMP-binding.1"
                     /evalue="3.90E-98"
                     /label="IE289_RS48385_AMP-binding.1"
                     /locus_tag="IE289_RS48385"
                     /protein_end="403"
                     /protein_start="7"
                     /score="320.7"
                     /specificity="substrate consensus: Trp"
                     /tool="antismash"
                     /translation="FESTVARRGGEPALIDGESTLGYAELNTRINRLARRLIAHGVGPD
                     SLVAVAMPKSSELIVAIMAVLKAGGAYLPLDPGYPAERLRFMLADARPVLLLRSSSVAP
                     LGAGPEELVLDDPAFRAACAALPGHDVAQHERRAVLRPEHLMYVIYTSGSTGTPKGVAV
                     PHSGVRDMAATQAAVLRAGPGDRVLQWASISFDAAFWDVSLALLSGAALVMVSADDLLP
                     GQPLWNTLFKYGITHAVLPPVALSETDAEDILLGGTVMSTGDSCTPTLVRKWSRARRMF
                     NGYGPTEVTVGATIGGPVRDAGDVGIGMPWIGNEVHVLDESLRPVPPGTEGELYIAGSG
                     LARGYLNRFGATAVKFVADPFGPPGSRMYRTGDRGRRGPDGELFFAGRADGQVKLR"
     aSModule        25195..26919
                     /complete
                     /domains="nrpspksdomains_IE289_RS48385_AMP-binding.1"
                     /domains="nrpspksdomains_IE289_RS48385_PCP.1"
                     /locus_tags="IE289_RS48385"
                     /monomer_pairings="Trp -> Trp"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       25381..25422
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48385_0001"
                     /evalue="5.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48385"
                     /protein_end="83"
                     /protein_start="69"
                     /score="19.4"
                     /tool="antismash"
                     /translation="MAVLKAGGAYLPLD"
     CDS_motif       25552..25575
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48385_0002"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48385"
                     /protein_end="134"
                     /protein_start="126"
                     /score="-3.4"
                     /tool="antismash"
                     /translation="RAACAALP"
     CDS_motif       25630..25689
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48385_0003"
                     /evalue="2.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE289_RS48385"
                     /protein_end="172"
                     /protein_start="152"
                     /score="32.2"
                     /tool="antismash"
                     /translation="MYVIYTSGSTGTPKGVAVPH"
     CDS_motif       25810..25839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48385_0004"
                     /evalue="4.40E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48385"
                     /protein_end="222"
                     /protein_start="212"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="LLSGAALVMV"
     CDS_motif       26173..26262
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48385_0005"
                     /evalue="7.20E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="IE289_RS48385"
                     /protein_end="363"
                     /protein_start="333"
                     /score="43.9"
                     /tool="antismash"
                     /translation="PPGTEGELYIAGSGLARGYLNRFGATAVKF"
     CDS_motif       26347..26412
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48385_0006"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE289_RS48385"
                     /protein_end="413"
                     /protein_start="391"
                     /score="36.7"
                     /tool="antismash"
                     /translation="FAGRADGQVKLRGFRVELGEIE"
     aSDomain        26722..26919
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48385_PCP.1"
                     /evalue="5.10E-23"
                     /label="IE289_RS48385_PCP.1"
                     /locus_tag="IE289_RS48385"
                     /protein_end="582"
                     /protein_start="516"
                     /score="73.1"
                     /tool="antismash"
                     /translation="VVCAIVRDILGVPEARLSDNFFQLGGHSVQATRLAARIRERFEVA
                     LSIRTVLEAATIGELAAAVES"
     gene            complement(26941..28128)
                     /locus_tag="IE289_RS48390"
                     /old_locus_tag="GCM10010317_099500"
     CDS             complement(26941..28128)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962803.1"
                     /locus_tag="IE289_RS48390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099500"
                     /product="cytochrome P450"
                     /protein_id="WP_190174518.1"
                     /sec_met_domain="p450 (E-value: 4.4e-20, bitscore: 62.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIPTELDLTDATAFVRHDAYEFWRDVRKSRPVYWHQGDPGFWVV
                     ARHADVLSCYADVRSLSSARGTVLDVLLSGGDSAGGKMLAVTDRPRHRELRNLMLRAFS
                     PRVLGAVEQKIWERTSRLIKTVTGQGEFDFAAEVAEHIPMNTICDLLSIPEADREKLLR
                     WNKLALSSHDAESDRLDSLEARNEIIGYFMDLARHRRGDPGDDVISMIATAEVGDRPLT
                     LEEVALNCYSLVLGGDESSRVSAICAVKTFAEHPAQWRALREGSAAIDTAVEEVLRWAT
                     PAMHFARTATRDMEIGGRRVRAGDIVTLWNTSANNDEEVFDQPRRFDPARSPNKHLSFG
                     HGPHFCVGAFLGRTELRALLSALTESVNEIEVCGKPTPIYSNFLNGYGSLPVAFR"
     gene            28316..29011
                     /locus_tag="IE289_RS48395"
                     /old_locus_tag="GCM10010317_099510"
     CDS             28316..29011
                     /GO_function="GO:0004833 - tryptophan 2,3-dioxygenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0019441 - tryptophan catabolic process to
                     kynurenine [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521686.1"
                     /locus_tag="IE289_RS48395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099510"
                     /product="tryptophan 2,3-dioxygenase family protein"
                     /protein_id="WP_229889618.1"
                     /transl_table=11
                     /translation="MSSLTYADYLRMESLLSLQEPRTPHTAGRAVVLAEQFFIITHQSC
                     ELWLKQLGADLDAAAEALLPPCDTHDLELGLEFLLRSGELIRVLQQQLLVLEKLPLRYF
                     AEFRSYLDTASGAQSAQFRRLTTLLGNSHHQGSLYEAFAAAVEYHGQTVDDVCRRGVES
                     GVLHRLAEALVDLGNGYWHWKVAHLALVSKMVGEQGGTGGSSGVDFLARRVTRPFPELR
                     RLRGKVHHP"
     gene            complement(29382..29786)
                     /locus_tag="IE289_RS48400"
                     /old_locus_tag="GCM10010317_099520"
     CDS             complement(29382..29786)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012698.5"
                     /locus_tag="IE289_RS48400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099520"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_079144904.1"
                     /transl_table=11
                     /translation="MEAGARPPVCNDPFEDWVRAPISREDLDARVKALQNRLDDRQIPT
                     LDSAGTLSYGPHSITISNVQTELMELLIEHFGEVVYRHELTQRLAERVQRPTRNSLDLH
                     IMRLRRRLLPTDLVIRTAWGRGYALETEAG"
     misc_feature    complement(29448..29450)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(30075..30287)
                     /locus_tag="IE289_RS48405"
                     /old_locus_tag="GCM10010317_099530"
     CDS             complement(30075..30287)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009: mbtH-like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964796.1"
                     /locus_tag="IE289_RS48405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099530"
                     /product="MbtH family protein"
                     /protein_id="WP_069926457.1"
                     /transl_table=11
                     /translation="MSTNPFDDENGQFHVLVNDEDQHSLWPAFAEVPAGWRSVFGPAAR
                     AESVAYVEEHWTDMRPRSLREAMNG"
     gene            complement(30334..39738)
                     /locus_tag="IE289_RS48410"
                     /old_locus_tag="GCM10010317_099540"
     CDS             complement(30334..39738)
                     /NRPS_PKS="Domain: Condensation_LCL (1-301). E-value:
                     4e-102. Score: 333.2. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (477-880). E-value: 2e-97.
                     Score: 318.3. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (968-1187). E-value: 1.9e-88. Score:
                     288.3. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_nMT.1"
                     /NRPS_PKS="Domain: PCP (1382-1449). E-value: 2.9e-28.
                     Score: 89.9. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1464-1765). E-value:
                     1.3e-113. Score: 370.9. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1935-2318). E-value:
                     6.8e-98. Score: 319.8. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_AMP-binding.2"
                     /NRPS_PKS="Domain: nMT (2408-2626). E-value: 4.8e-97.
                     Score: 316.7. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_nMT.2"
                     /NRPS_PKS="Domain: PCP (2813-2882). E-value: 3.3e-27.
                     Score: 86.5. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2904-3128). E-value:
                     4.8e-39. Score: 127.0. Matches aSDomain:
                     nrpspksdomains_IE289_RS48410_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1209: polyketide synthase associated protein papA3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="IE289_RS48410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099540"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_190174519.1"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-106, bitscore:
                     346.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-19, bitscore:
                     60.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.4e-69, bitscore:
                     224.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.2e-32, bitscore:
                     104.9, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.9e-09, bitscore: 27.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPLSYAQRRMWFINRFEGPSSTYNIPLLLRCHGPLDTVALRAAF
                     RDVMIRHEVLRTVFAETDGQPYQRVLDSDEIELPWQDWGRVAPERIPGVVASVSGSWID
                     LSTDVPLRGCVLQSGDEEFLVVLVIHHIAGDGGSLAPLARDVSTAYRARVTGTAPDWSE
                     LPVQYSDYALWQHEMLGDEKDPDSVVAVQSAYWREELAGVSKPLPLPLDRPRPEVASFR
                     GGSVPVGLPAELRAGVEKLAQTHGVTTSIVLQAALVTLLHRLGGGKDVTVGSPIAGRTE
                     EALNELVGFFVNTWTLRVQVTADQPFEWVLEQVRKKALAAYDHQDVPFERLVELLRPER
                     STAHHPLFQVVLAWQNNTPPHLDLPGLTVTMEPLPTGSAKFDLFFNLAPDESTGSVVGE
                     IEYATDLFDRSTVEEIAARFVAVVEEVVADPRTPVGAAGEAGPGRSGGTLDAAERRKIL
                     VEWNDTARPVHCPGPVHLLFEEQAARRPDATALRWAGGTMTYGELNRWANRVAWDLKER
                     GVGPETVVGVGVPRGPVMIAAVLGVLKAGGAYLPLEPALPADRVAGMLADAGCSLVLST
                     PDTERWALPDGVRLVELTDARSPGPDHDPEPAAGPDNTAYIIFTSGSTGKPKGVAVTHR
                     PVHNLLDWCYRTFAFGPDDVALCVTSLGFDLSVFDVFGLLGCGGGVYIADAVQQRDPQL
                     LLDVLLTEPITFWDSVPTTLNQVASLLTEDGGYEGTDDLRLVFLSGDYTPLSLPDEVRR
                     VFTGAEIVSLGGATEATVWSNYFRVREIDPAWRSIPYGRPIDNARYYVLDENMEPCPVG
                     VEGDLYIGGDCLCVGYVNRPELTAERFVRDPFSAREGDRLYRTGDRASFFPDGNICFLG
                     RADNQVKLRGFRVEPGEIEHTLVRHPAVRQAIVTAREDRPGDLRLVAYVVPDTGALRPD
                     GDADEQVGEWQEVYDQAYSHDNGHGFGEDFTGWNSSFTGEPIPLDEMRDWRDAAVERVL
                     CWSPERVLELGVGTGLLLAHIAGRVEEYWATDFSQAVIDRLSDQVTRAGLADRVRLRRQ
                     AADDLTGLPRGTFDTVVLNSVVQYFPDERYLARVLDGAWELLAPGGRIVLGDIRRASSL
                     RTLQTGVQRTKHPDAAPAVLRTTVDQAVLLEKELVVDPESFLRWADRAGATGADIRAKN
                     GIHHNELTRHRYEVVLHKPGAAPADAPRRLDVVPTLTWEGDLGRLADRLRDRSEPAVRI
                     TGIPNARLTEEAAAARALGLDDSAAPELPPLDPAEIRAWAARHGWDAVPTWSADAVDLL
                     DVIVLRDGPAAGTTLTGTYLPATDGRTPANDPAAAAAVTALLPALRGHLRETLPEYMVP
                     AAIVPIAAVPLTDNGKPDRRALPVPDYVVGGGRAPSTPEEESLCALFAAVLGLDQVGVD
                     DNFFTVGGHSLLATRLVSRIRAEHGVEIPIRVVFQSPTVAELAAHLNTLSNVRPPLRPQ
                     ARPERLPLSYAQQRLWFIHRFEGPSATYNVTLALRMRGELDAAALRRAVHDVVVRHESL
                     RTVFGEADGQPYQRILEPAVVEVPWEEREITEAELPGALRAAARRPFDLAAEIPIRSWL
                     LRTGEREAVFLIGAHHIAADGWSALPLAQDLTTAYEARRAGRAPEWEPLPVQYADYTLW
                     QRELLGDTDTPGSLYRRQLDYWTTQLAGLPETVSPPADRPRPAAASYAGDLVPLALDPQ
                     LTDGVRRLARETGATVSMVLQAALAALLTRLGAGTDVSIGSPIAGRTDEALNRLVGFFV
                     NTWVLRADTSGDPSFAELVGRVRESSLAAYDHQDIPFEHLVEKLNPVRSPAHHPLFQVC
                     LALQNNARPEFHLAGLTVTEEPFSPGTSRFDLFISVTEQDEDGAPARIEGFAEYATELF
                     DAGTVSTLLDRWLHFLRQVVAAPETPIGSVGVLAEHERAALSGWGGGGRDARFDAGTLP
                     ERFAATAAATPDATALVSADGTLAWTYAELDRWANRLAHHFRARGARPDSRVALVLERS
                     PLLVAAVLGVLKTGAAYVPVDPNYPPERIDYLLADLAPAVTVYEDLAEEDLDGLPDSPP
                     ETEGVGEYAVAYVMYTSGSTGRPKGVEVTHRNVVDLALDGCFGTGAHHRVLLHSPHTFD
                     ASTYEMWVPLLGGGTAVVARAGRPDTAELARVITEREVTGLWLTAGLFAVMAEQHAECF
                     GAVQEVWAGGDVLSPTAVRAVLDACPGVTVVNGYGPTETTTFASRHRVASAAECTDPLP
                     IGSPMDGSRLLVLDDRLLPVPPGVVGELYIGGDGVARGYAGRPGLTATRFVPDPSGQSG
                     ARMYRTGDLVRWNTAGCLQYISRSDEQIKLRGFRVEPGELETVLREEDGVANAVVTVRQ
                     DRLGERRMVAYVVPDGSVSTGRDAAEQVGEWREIYDTMYGGTEVDTEESEDFTGWNSSY
                     TSRPIPLPEMRAWREAVLRRVRSLRPRRVLEIGVGSGLLLGPLAPEAEEYWGTDFSAPV
                     VERLRARTGADPVLSDKVTLRCQPADDAEGLPTGYFDTVILNSVVQYFPDADYLTRVLD
                     LAMDRLAPGGRVVIGDVRNYRTLRTFAAAVHRCRQPDDGPAAVQAAVERAVLGEKELVV
                     DPGFFTRWAETRPDAVAADIRLKQGTHHNELTRHRYEVVLHKAPARPLHLGDLPEEVWG
                     AEVRELADLETALARQGGRLRLTRIPNTRLAGEAAEWGAPAEVGGTLDPADLEAWGARR
                     GLAVYCTWSAQAGDCFEAIVMPDVDAVCCDGLYRPAGASSARLANVPAVSRRVSRLPSL
                     LRERLAGRLPEFMMPADIVVLDRLPLTENGKVDRAALPEPDPVGGEHRAPRTPREEELA
                     ALFAEVLGMDRIGIDDDFFACGGHSLRLTRLVWRIHEKLGVDVPIRTVFQYPTVAALAA
                     QLSADTEADFEDPFAVLLPIRTEGHRPPLWWLHPGGGLSWPYLGFARHVEPSWPLYGIQ
                     ARGFDGTTPPAGSIEEMVEDYLGQVLQVQPSGPYHLLGWSFGGTLAHAMAAELQRRGHE
                     VALLALLDAAPSSHFADLEALDEAMVRRYLANYMGHLAGMEEYPSLVTTASSIFIGQME
                     QMRRFTSPRYRGDVVFFNALLDPETHDKRELDEELDVLWQEHVDGRVQRIDIACAHNEM
                     YWPRNAAEISRAINRYLRAAQ"
     aSDomain        complement(30355..31026)
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_Thioesterase.1"
                     /evalue="4.80E-39"
                     /label="IE289_RS48410_Thioesterase.1"
                     /locus_tag="IE289_RS48410"
                     /protein_end="3128"
                     /protein_start="2904"
                     /score="127.0"
                     /tool="antismash"
                     /translation="PLWWLHPGGGLSWPYLGFARHVEPSWPLYGIQARGFDGTTPPAGS
                     IEEMVEDYLGQVLQVQPSGPYHLLGWSFGGTLAHAMAAELQRRGHEVALLALLDAAPSS
                     HFADLEALDEAMVRRYLANYMGHLAGMEEYPSLVTTASSIFIGQMEQMRRFTSPRYRGD
                     VVFFNALLDPETHDKRELDEELDVLWQEHVDGRVQRIDIACAHNEMYWPRNAAEISRAI
                     NR"
     aSModule        complement(30355..35346)
                     /complete
                     /domains="nrpspksdomains_IE289_RS48410_Condensation_LCL.2"
                     /domains="nrpspksdomains_IE289_RS48410_AMP-binding.2"
                     /domains="nrpspksdomains_IE289_RS48410_nMT.2"
                     /domains="nrpspksdomains_IE289_RS48410_PCP.2"
                     /domains="nrpspksdomains_IE289_RS48410_Thioesterase.1"
                     /final_module
                     /locus_tags="IE289_RS48410"
                     /monomer_pairings="Val -> NMe-Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(30772..30846)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0021"
                     /evalue="5.70E-15"
                     /label="NRPS-te1"
                     /locus_tag="IE289_RS48410"
                     /protein_end="2989"
                     /protein_start="2964"
                     /score="47.5"
                     /tool="antismash"
                     /translation="QPSGPYHLLGWSFGGTLAHAMAAEL"
     aSDomain        complement(31093..31299)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_PCP.2"
                     /evalue="3.30E-27"
                     /label="IE289_RS48410_PCP.2"
                     /locus_tag="IE289_RS48410"
                     /protein_end="2882"
                     /protein_start="2813"
                     /score="86.5"
                     /tool="antismash"
                     /translation="EEELAALFAEVLGMDRIGIDDDFFACGGHSLRLTRLVWRIHEKLG
                     VDVPIRTVFQYPTVAALAAQLSAD"
     aSDomain        complement(31861..32514)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_nMT.2"
                     /domain_subtypes="nMT"
                     /evalue="4.80E-97"
                     /label="IE289_RS48410_nMT.2"
                     /locus_tag="IE289_RS48410"
                     /protein_end="2626"
                     /protein_start="2408"
                     /score="316.7"
                     /tool="antismash"
                     /translation="PIPLPEMRAWREAVLRRVRSLRPRRVLEIGVGSGLLLGPLAPEAE
                     EYWGTDFSAPVVERLRARTGADPVLSDKVTLRCQPADDAEGLPTGYFDTVILNSVVQYF
                     PDADYLTRVLDLAMDRLAPGGRVVIGDVRNYRTLRTFAAAVHRCRQPDDGPAAVQAAVE
                     RAVLGEKELVVDPGFFTRWAETRPDAVAADIRLKQGTHHNELTRHRYEVVLHKAP"
     CDS_motif       complement(32755..32820)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0020"
                     /evalue="5.50E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="IE289_RS48410"
                     /protein_end="2328"
                     /protein_start="2306"
                     /score="28.3"
                     /tool="antismash"
                     /translation="YISRSDEQIKLRGFRVEPGELE"
     aSDomain        complement(32785..33933)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_AMP-binding.2"
                     /evalue="6.80E-98"
                     /label="IE289_RS48410_AMP-binding.2"
                     /locus_tag="IE289_RS48410"
                     /protein_end="2318"
                     /protein_start="1935"
                     /score="319.8"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FAATAAATPDATALVSADGTLAWTYAELDRWANRLAHHFRARGAR
                     PDSRVALVLERSPLLVAAVLGVLKTGAAYVPVDPNYPPERIDYLLADLAPAVTVYEDLA
                     EEDLDGLPDSPPETEGVGEYAVAYVMYTSGSTGRPKGVEVTHRNVVDLALDGCFGTGAH
                     HRVLLHSPHTFDASTYEMWVPLLGGGTAVVARAGRPDTAELARVITEREVTGLWLTAGL
                     FAVMAEQHAECFGAVQEVWAGGDVLSPTAVRAVLDACPGVTVVNGYGPTETTTFASRHR
                     VASAAECTDPLPIGSPMDGSRLLVLDDRLLPVPPGVVGELYIGGDGVARGYAGRPGLTA
                     TRFVPDPSGQSGARMYRTGDLVRWNTAGCLQYISRSDEQIKLR"
     CDS_motif       complement(32905..32994)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0019"
                     /evalue="3.70E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="IE289_RS48410"
                     /protein_end="2278"
                     /protein_start="2248"
                     /score="51.2"
                     /tool="antismash"
                     /translation="PPGVVGELYIGGDGVARGYAGRPGLTATRF"
     CDS_motif       complement(33496..33555)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0018"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="IE289_RS48410"
                     /protein_end="2081"
                     /protein_start="2061"
                     /score="29.9"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGRPKGVEVTH"
     CDS_motif       complement(33700..33741)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0017"
                     /evalue="8.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48410"
                     /protein_end="2013"
                     /protein_start="1999"
                     /score="15.8"
                     /tool="antismash"
                     /translation="LGVLKTGAAYVPVD"
     CDS_motif       complement(34285..34404)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0016"
                     /evalue="6.80E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1818"
                     /protein_start="1778"
                     /score="66.7"
                     /tool="antismash"
                     /translation="RESSLAAYDHQDIPFEHLVEKLNPVRSPAHHPLFQVCLAL"
     aSDomain        complement(34444..35346)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.30E-113"
                     /label="IE289_RS48410_Condensation_LCL.2"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1765"
                     /protein_start="1464"
                     /score="370.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAADG"
                     /tool="antismash"
                     /translation="ERLPLSYAQQRLWFIHRFEGPSATYNVTLALRMRGELDAAALRRA
                     VHDVVVRHESLRTVFGEADGQPYQRILEPAVVEVPWEEREITEAELPGALRAAARRPFD
                     LAAEIPIRSWLLRTGEREAVFLIGAHHIAADGWSALPLAQDLTTAYEARRAGRAPEWEP
                     LPVQYADYTLWQRELLGDTDTPGSLYRRQLDYWTTQLAGLPETVSPPADRPRPAAASYA
                     GDLVPLALDPQLTDGVRRLARETGATVSMVLQAALAALLTRLGAGTDVSIGSPIAGRTD
                     EALNRLVGFFVNTWVLRADT"
     CDS_motif       complement(34453..34542)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0015"
                     /evalue="1.50E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1762"
                     /protein_start="1732"
                     /score="43.0"
                     /tool="antismash"
                     /translation="DVSIGSPIAGRTDEALNRLVGFFVNTWVLR"
     CDS_motif       complement(34810..34848)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0014"
                     /evalue="3.90E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1643"
                     /protein_start="1630"
                     /score="16.2"
                     /tool="antismash"
                     /translation="QYADYTLWQRELL"
     CDS_motif       complement(34897..34959)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0013"
                     /evalue="9.00E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1614"
                     /protein_start="1593"
                     /score="27.9"
                     /tool="antismash"
                     /translation="HHIAADGWSALPLAQDLTTAY"
     CDS_motif       complement(35167..35280)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0012"
                     /evalue="4.20E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1524"
                     /protein_start="1486"
                     /score="54.5"
                     /tool="antismash"
                     /translation="ATYNVTLALRMRGELDAAALRRAVHDVVVRHESLRTVF"
     CDS_motif       complement(35299..35331)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0011"
                     /evalue="9.00E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1480"
                     /protein_start="1469"
                     /score="8.8"
                     /tool="antismash"
                     /translation="SYAQQRLWFIH"
     aSDomain        complement(35392..35592)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_PCP.1"
                     /evalue="2.90E-28"
                     /label="IE289_RS48410_PCP.1"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1449"
                     /protein_start="1382"
                     /score="89.9"
                     /tool="antismash"
                     /translation="EESLCALFAAVLGLDQVGVDDNFFTVGGHSLLATRLVSRIRAEHG
                     VEIPIRVVFQSPTVAELAAHLN"
     aSModule        complement(35392..39735)
                     /complete
                     /domains="nrpspksdomains_IE289_RS48410_Condensation_LCL.1"
                     /domains="nrpspksdomains_IE289_RS48410_AMP-binding.1"
                     /domains="nrpspksdomains_IE289_RS48410_nMT.1"
                     /domains="nrpspksdomains_IE289_RS48410_PCP.1"
                     /locus_tags="IE289_RS48410"
                     /monomer_pairings="Cys -> NMe-Cys"
                     /tool="antismash"
                     /type="nrps"
     misc_feature    complement(36094..36096)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(36178..36834)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="1.90E-88"
                     /label="IE289_RS48410_nMT.1"
                     /locus_tag="IE289_RS48410"
                     /protein_end="1187"
                     /protein_start="968"
                     /score="288.3"
                     /tool="antismash"
                     /translation="GEPIPLDEMRDWRDAAVERVLCWSPERVLELGVGTGLLLAHIAGR
                     VEEYWATDFSQAVIDRLSDQVTRAGLADRVRLRRQAADDLTGLPRGTFDTVVLNSVVQY
                     FPDERYLARVLDGAWELLAPGGRIVLGDIRRASSLRTLQTGVQRTKHPDAAPAVLRTTV
                     DQAVLLEKELVVDPESFLRWADRAGATGADIRAKNGIHHNELTRHRYEVVLHKPGA"
     CDS_motif       complement(37069..37134)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0010"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE289_RS48410"
                     /protein_end="890"
                     /protein_start="868"
                     /score="36.7"
                     /tool="antismash"
                     /translation="FLGRADNQVKLRGFRVEPGEIE"
     aSDomain        complement(37099..38307)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_AMP-binding.1"
                     /evalue="2.00E-97"
                     /label="IE289_RS48410_AMP-binding.1"
                     /locus_tag="IE289_RS48410"
                     /protein_end="880"
                     /protein_start="477"
                     /score="318.3"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FEEQAARRPDATALRWAGGTMTYGELNRWANRVAWDLKERGVGPE
                     TVVGVGVPRGPVMIAAVLGVLKAGGAYLPLEPALPADRVAGMLADAGCSLVLSTPDTER
                     WALPDGVRLVELTDARSPGPDHDPEPAAGPDNTAYIIFTSGSTGKPKGVAVTHRPVHNL
                     LDWCYRTFAFGPDDVALCVTSLGFDLSVFDVFGLLGCGGGVYIADAVQQRDPQLLLDVL
                     LTEPITFWDSVPTTLNQVASLLTEDGGYEGTDDLRLVFLSGDYTPLSLPDEVRRVFTGA
                     EIVSLGGATEATVWSNYFRVREIDPAWRSIPYGRPIDNARYYVLDENMEPCPVGVEGDL
                     YIGGDCLCVGYVNRPELTAERFVRDPFSAREGDRLYRTGDRASFFPDGNICFLGRADNQ
                     VKLR"
     CDS_motif       complement(37222..37311)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0009"
                     /evalue="9.40E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="IE289_RS48410"
                     /protein_end="839"
                     /protein_start="809"
                     /score="43.5"
                     /tool="antismash"
                     /translation="PVGVEGDLYIGGDCLCVGYVNRPELTAERF"
     CDS_motif       complement(37837..37896)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0008"
                     /evalue="2.90E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE289_RS48410"
                     /protein_end="634"
                     /protein_start="614"
                     /score="32.0"
                     /tool="antismash"
                     /translation="AYIIFTSGSTGKPKGVAVTH"
     CDS_motif       complement(38083..38121)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0007"
                     /evalue="2.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48410"
                     /protein_end="552"
                     /protein_start="539"
                     /score="14.6"
                     /tool="antismash"
                     /translation="LGVLKAGGAYLPL"
     CDS_motif       complement(38677..38796)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0006"
                     /evalue="1.00E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IE289_RS48410"
                     /protein_end="354"
                     /protein_start="314"
                     /score="72.6"
                     /tool="antismash"
                     /translation="RKKALAAYDHQDVPFERLVELLRPERSTAHHPLFQVVLAW"
     aSDomain        complement(38836..39735)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48410_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.00E-102"
                     /label="IE289_RS48410_Condensation_LCL.1"
                     /locus_tag="IE289_RS48410"
                     /protein_end="301"
                     /protein_start="1"
                     /score="333.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAGDG"
                     /tool="antismash"
                     /translation="TPLSYAQRRMWFINRFEGPSSTYNIPLLLRCHGPLDTVALRAAFR
                     DVMIRHEVLRTVFAETDGQPYQRVLDSDEIELPWQDWGRVAPERIPGVVASVSGSWIDL
                     STDVPLRGCVLQSGDEEFLVVLVIHHIAGDGGSLAPLARDVSTAYRARVTGTAPDWSEL
                     PVQYSDYALWQHEMLGDEKDPDSVVAVQSAYWREELAGVSKPLPLPLDRPRPEVASFRG
                     GSVPVGLPAELRAGVEKLAQTHGVTTSIVLQAALVTLLHRLGGGKDVTVGSPIAGRTEE
                     ALNELVGFFVNTWTLRVQV"
     CDS_motif       complement(38845..38934)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0005"
                     /evalue="7.60E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="IE289_RS48410"
                     /protein_end="298"
                     /protein_start="268"
                     /score="40.8"
                     /tool="antismash"
                     /translation="DVTVGSPIAGRTEEALNELVGFFVNTWTLR"
     CDS_motif       complement(39202..39240)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0004"
                     /evalue="3.50E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="IE289_RS48410"
                     /protein_end="179"
                     /protein_start="166"
                     /score="16.3"
                     /tool="antismash"
                     /translation="QYSDYALWQHEML"
     CDS_motif       complement(39289..39354)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0003"
                     /evalue="3.40E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="IE289_RS48410"
                     /protein_end="150"
                     /protein_start="128"
                     /score="22.9"
                     /tool="antismash"
                     /translation="IHHIAGDGGSLAPLARDVSTAY"
     CDS_motif       complement(39559..39672)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0002"
                     /evalue="3.20E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="IE289_RS48410"
                     /protein_end="60"
                     /protein_start="22"
                     /score="51.7"
                     /tool="antismash"
                     /translation="TYNIPLLLRCHGPLDTVALRAAFRDVMIRHEVLRTVFA"
     CDS_motif       complement(39697..39726)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48410_0001"
                     /evalue="1.30E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="IE289_RS48410"
                     /protein_end="14"
                     /protein_start="4"
                     /score="8.4"
                     /tool="antismash"
                     /translation="SYAQRRMWFI"
     gene            complement(39747..47612)
                     /locus_tag="IE289_RS48415"
                     /old_locus_tag="GCM10010317_099550"
     CDS             complement(39747..47612)
                     /NRPS_PKS="Domain: Condensation_Starter (28-335). E-value:
                     1.9e-55. Score: 180.3. Matches aSDomain:
                     nrpspksdomains_IE289_RS48415_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (497-890). E-value:
                     8.5e-118. Score: 385.4. Matches aSDomain:
                     nrpspksdomains_IE289_RS48415_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1011-1079). E-value: 6.1e-22.
                     Score: 69.6. Matches aSDomain:
                     nrpspksdomains_IE289_RS48415_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1096-1401). E-value:
                     8.8e-113. Score: 369.5. Matches aSDomain:
                     nrpspksdomains_IE289_RS48415_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1414-1581). E-value: 3.4e-29.
                     Score: 93.6. Matches aSDomain:
                     nrpspksdomains_IE289_RS48415_TIGR01720.1"
                     /NRPS_PKS="Domain: Cglyc (1588-1885). E-value: 2.3e-107.
                     Score: 350.6. Matches aSDomain:
                     nrpspksdomains_IE289_RS48415_Cglyc.1"
                     /NRPS_PKS="Domain: AMP-binding (2050-2431). E-value:
                     9.3e-107. Score: 349.1. Matches aSDomain:
                     nrpspksdomains_IE289_RS48415_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2538-2603). E-value: 1.5e-28.
                     Score: 90.8. Matches aSDomain:
                     nrpspksdomains_IE289_RS48415_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /locus_tag="IE289_RS48415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099550"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_308435139.1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-124, bitscore:
                     406.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.4e-64, bitscore:
                     209.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-19, bitscore:
                     61.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRDKYRHGEAIDRETTFAGGIWMGCTGVTSAQEAMWLAQEFTPD
                     VPNNVATLWDIDGDLDTALLAAALGAAVAEADALKVNFRRDDHGLRPVARDLGAWEPFR
                     LDVGDAADPADAARAVVADLVRRPFDLTEDALLRIGSIRLGPGRHLLVLVFHHILTDAF
                     GVLTLLSRRIAEIYRALRAGSALPEGAPNPPGDAAAKDAVYRESQRFADAERFWRDYLA
                     EDLPAARLPAGVRPGTDAPTGGPGYWDGLTAPQGMATRTATVPAVELAAWEHASAAAGT
                     SVPDLIASAATAFLGHMCGLSEQLLTITVNHRVGALRRSLGLLSNRVPLRSRVDPAADF
                     VELAEALGRERRRVLRHARHDISLIKRATGHAGDARSPFGAVVNVLPSVEALDLAGATA
                     HFAGGTFGVIDEVMVCVYTDGRADSDLYVRFDAPRAEYDDQDIAGLAERFVTFLRRALA
                     DPHAPVGTVSALHPAERRALLTEYAGPTVTPPPTTLTELLDRQARATPDAVAVTFEDTR
                     VTYRELAERSGRLARLLTERGAGPERFVAVAVPRSLELVVALVAVLRAGAAYVPVDPDY
                     PAARVEFMLADAGPALLLTVKDTADRLPRTDVPVVMVDDAPLTEEPVRSAPHRVDHPAY
                     MIYTSGSTGRPKGAVVTHAAIVNRLLWMQDRFRLDGSDRVLQKTSASFDVSVWEFFWPL
                     ITGATLVVARPDGHRDPDYLAEVIRRAGVTTAHFVPSMLAEFVTEETAAACTGLRRVVC
                     SGEALPAELAARFHRTFGVPLHNLYGPTEAAVDVTAWQYRPGARTIPIGTPIWNTALYV
                     LDSRLRPLPPGVFGDLYIAGAGLARGYHDRRALTAERFVACPFGEPGRRMYRTGDLARW
                     NTDGELEFAGRADHQVKIRGFRVEPQEIEDTLTDHPGVLRAAVVARPGRAADGAAQLVA
                     YVVPATSGGNGGTGTEWDLHAGLDIAELRGFVAARLPAHLVPAAFVALDRMPLTANGKL
                     DRAGLPEPEVTGRAHRPPRTGDESLLAAAFAEVLGLSHIGVDDDFFTLGGDSIRAIQVV
                     GRARAGGLALTPRTVFECRTVAALAQAATRDTAPVALAELEGGGVGLLPLPPMARLYAE
                     RGPGLDRLAQWLVLELPAAVDLPGLTAAVRAVLDRHDVLRSRLTDDGLLVQPPGTPDAG
                     GFVDRVDCPGDWGGEEWQTLLRAKAAEAVRHIDARAGRMLRLVWFPGAAGGPGRLLVVA
                     HHLVVDGMSWRVLLPDLAAAWRQVQEGRPPALPRVGTSLRRWLHALADEAARPGRVAEV
                     PLWRDLLEAPVAPVGSRPLDPGRDLTSTTDTVRVELPADLTDAILTSVPAAYRSGADDV
                     LLTALVLALARERRGLTDGTTVVRLEGHGRQEELVPGADLSRTAGWFTTVTPVRIDVSG
                     IDVDAAITGGAAAGDALKRVKEQRRALPDQGIGYTLLRYLNDDTAALLSPYPADDIGFN
                     FLGRFTFERPEPAPGEDPTRGSGWTPAPECAELVAAPAADMPAPSALELNALVTGTGDD
                     ARLTALFTFATGVLTTDEVRALSGTWCAALRGLRSLVASGGRGLTPSDVPLVTVGQEEL
                     DGWQRRFGRVSDVWPLTPLQDGLLYHTMLAQSASEAYQTQFVFRLEGAVDPARLRAAGQ
                     ALLDRHPNLRVAFRPSATGEPVQVVVDDVPLPWRHLDLTGEADAATRLEEILAEERDAR
                     FRPESPPLLRLTLVTLGPQHAELALTAHHVLLDGWSVPLVERELMQLYGADGVDTAPAR
                     PHGYRDFLSWLSRQDTARSARAWAEELAGVAEPTLLAPTTPGARPAGSGSEQIDVPLTG
                     EDTTMLARRAAEWGLTPNTLVQGAWAMVLAQLTGREDVLFGATVAGRPSGLPGADTMIG
                     LFINTVPVRVRCTPADPVPEVLGRLQDAQARLLDHHHLGLADIQRATGLNALFDTLVVF
                     ESFPVDRSGRSAAGASAQPVVSGIRPYAPPHYPLTVIAAADPLLRISFQYRRNAFERTA
                     VEALADRLVRVLRQIAAGPRTTVGALDVLSDAEREQVLHGWNDTTVPPPERTVPELIAA
                     RAAATPDTVCVEFRGHRLTFRELDERAGRLAHWLAGQGVGPESRVVVLLPRSADLVVAL
                     LAVWKAGGTYVPVDPEYPAARVRAVVEDSAPVLVLDEERLAGVDLSDRSPHPAHGPRVP
                     AGADHAAYVIYTSGSTGTPKGVVVRHGALAILLTGMQDRFSFTPDDRLLACATVAFDIA
                     ALELFLPLLAGGRVVLAGKDDITQPTALLDLVERSGVTVMQATPALWQSLVTHAPACLT
                     GLRVISTGEALPLALAETLCRHAAEVTNLYGPTETTVYATAARLLPGHCGMPPSVGGPV
                     AGTRILVLDRTLRPVPPGAAGDLWIAGEGLARGYHDRPGMTAERFVACPFGPPGERMYR
                     SGDLARWTVTGEVEYLGRSDHQIKLRGFRIEPAEIEHTLTRHPAVRRAVVIDREDRPGD
                     RRLVAYVVPETGTEPPTTELLREAVGERLPAYMIPAAFVTLTELPLTPNGKLDRSALPR
                     PEFGGDEYRAPRSPREQTLCALFAEVLGAERIGLDDDFFVLGGHSLMATRLVARVRAEM
                     GVEIPMRVLFTAPTVAELTDRWNEMSASTRMPLRRMTER"
     aSDomain        complement(39804..39998)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48415_PCP.2"
                     /evalue="1.50E-28"
                     /label="IE289_RS48415_PCP.2"
                     /locus_tag="IE289_RS48415"
                     /protein_end="2603"
                     /protein_start="2538"
                     /score="90.8"
                     /tool="antismash"
                     /translation="EQTLCALFAEVLGAERIGLDDDFFVLGGHSLMATRLVARVRAEMG
                     VEIPMRVLFTAPTVAELTDR"
     aSModule        complement(39804..42848)
                     /complete
                     /domains="nrpspksdomains_IE289_RS48415_Cglyc.1"
                     /domains="nrpspksdomains_IE289_RS48415_AMP-binding.2"
                     /domains="nrpspksdomains_IE289_RS48415_PCP.2"
                     /locus_tags="IE289_RS48415"
                     /monomer_pairings="Ala -> Ala"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(40290..40355)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0023"
                     /evalue="4.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE289_RS48415"
                     /protein_end="2441"
                     /protein_start="2419"
                     /score="34.7"
                     /tool="antismash"
                     /translation="YLGRSDHQIKLRGFRIEPAEIE"
     aSDomain        complement(40320..41462)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48415_AMP-binding.2"
                     /evalue="9.30E-107"
                     /label="IE289_RS48415_AMP-binding.2"
                     /locus_tag="IE289_RS48415"
                     /protein_end="2431"
                     /protein_start="2050"
                     /score="349.1"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="ARAAATPDTVCVEFRGHRLTFRELDERAGRLAHWLAGQGVGPESR
                     VVVLLPRSADLVVALLAVWKAGGTYVPVDPEYPAARVRAVVEDSAPVLVLDEERLAGVD
                     LSDRSPHPAHGPRVPAGADHAAYVIYTSGSTGTPKGVVVRHGALAILLTGMQDRFSFTP
                     DDRLLACATVAFDIAALELFLPLLAGGRVVLAGKDDITQPTALLDLVERSGVTVMQATP
                     ALWQSLVTHAPACLTGLRVISTGEALPLALAETLCRHAAEVTNLYGPTETTVYATAARL
                     LPGHCGMPPSVGGPVAGTRILVLDRTLRPVPPGAAGDLWIAGEGLARGYHDRPGMTAER
                     FVACPFGPPGERMYRSGDLARWTVTGEVEYLGRSDHQIKLR"
     CDS_motif       complement(40440..40529)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0022"
                     /evalue="7.00E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="IE289_RS48415"
                     /protein_end="2391"
                     /protein_start="2361"
                     /score="47.1"
                     /tool="antismash"
                     /translation="PPGAAGDLWIAGEGLARGYHDRPGMTAERF"
     CDS_motif       complement(40641..40664)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0021"
                     /evalue="1.10E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="IE289_RS48415"
                     /protein_end="2324"
                     /protein_start="2316"
                     /score="5.8"
                     /tool="antismash"
                     /translation="YGPTETTV"
     CDS_motif       complement(41028..41087)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0020"
                     /evalue="2.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="IE289_RS48415"
                     /protein_end="2195"
                     /protein_start="2175"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVVVRH"
     CDS_motif       complement(41241..41282)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0019"
                     /evalue="4.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48415"
                     /protein_end="2124"
                     /protein_start="2110"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LAVWKAGGTYVPVD"
     CDS_motif       complement(41802..41915)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0018"
                     /evalue="5.10E-18"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1937"
                     /protein_start="1899"
                     /score="57.5"
                     /tool="antismash"
                     /translation="QDAQARLLDHHHLGLADIQRATGLNALFDTLVVFESFP"
     aSDomain        complement(41958..42848)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48415_Cglyc.1"
                     /domain_subtypes="Cglyc"
                     /evalue="2.30E-107"
                     /label="IE289_RS48415_Cglyc.1"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1885"
                     /protein_start="1588"
                     /score="350.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHVLLDG"
                     /tool="antismash"
                     /translation="VSDVWPLTPLQDGLLYHTMLAQSASEAYQTQFVFRLEGAVDPARL
                     RAAGQALLDRHPNLRVAFRPSATGEPVQVVVDDVPLPWRHLDLTGEADAATRLEEILAE
                     ERDARFRPESPPLLRLTLVTLGPQHAELALTAHHVLLDGWSVPLVERELMQLYGADGVD
                     TAPARPHGYRDFLSWLSRQDTARSARAWAEELAGVAEPTLLAPTTPGARPAGSGSEQID
                     VPLTGEDTTMLARRAAEWGLTPNTLVQGAWAMVLAQLTGREDVLFGATVAGRPSGLPGA
                     DTMIGLFINTVPVRVR"
     CDS_motif       complement(41964..42059)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0017"
                     /evalue="2.50E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1883"
                     /protein_start="1851"
                     /score="58.5"
                     /tool="antismash"
                     /translation="DVLFGATVAGRPSGLPGADTMIGLFINTVPVR"
     CDS_motif       complement(42378..42440)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0016"
                     /evalue="3.30E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1745"
                     /protein_start="1724"
                     /score="32.4"
                     /tool="antismash"
                     /translation="HHVLLDGWSVPLVERELMQLY"
     CDS_motif       complement(42657..42770)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0015"
                     /evalue="5.30E-17"
                     /label="C2_DCL_024-062"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1652"
                     /protein_start="1614"
                     /score="54.1"
                     /tool="antismash"
                     /translation="AYQTQFVFRLEGAVDPARLRAAGQALLDRHPNLRVAFR"
     CDS_motif       complement(42798..42833)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0014"
                     /evalue="1.10E-03"
                     /label="C1_dual_004-017"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1605"
                     /protein_start="1593"
                     /score="12.0"
                     /tool="antismash"
                     /translation="PLTPLQDGLLYH"
     aSDomain        complement(42870..43370)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48415_TIGR01720.1"
                     /evalue="3.40E-29"
                     /label="IE289_RS48415_TIGR01720.1"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1581"
                     /protein_start="1414"
                     /score="93.6"
                     /tool="antismash"
                     /translation="AGDALKRVKEQRRALPDQGIGYTLLRYLNDDTAALLSPYPADDIG
                     FNFLGRFTFERPEPAPGEDPTRGSGWTPAPECAELVAAPAADMPAPSALELNALVTGTG
                     DDARLTALFTFATGVLTTDEVRALSGTWCAALRGLRSLVASGGRGLTPSDVPLVTVGQE
                     ELDG"
     aSModule        complement(42870..47528)
                     /complete
                     /domains="nrpspksdomains_IE289_RS48415_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_IE289_RS48415_AMP-binding.1"
                     /domains="nrpspksdomains_IE289_RS48415_PCP.1"
                     /domains="nrpspksdomains_IE289_RS48415_Epimerization.1"
                     /domains="nrpspksdomains_IE289_RS48415_TIGR01720.1"
                     /locus_tags="IE289_RS48415"
                     /monomer_pairings="Ser -> D-Ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(43287..43349)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0013"
                     /evalue="4.00E-10"
                     /label="NRPS-E6"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1442"
                     /protein_start="1421"
                     /score="31.8"
                     /tool="antismash"
                     /translation="VKEQRRALPDQGIGYTLLRYL"
     aSDomain        complement(43410..44324)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48415_Epimerization.1"
                     /evalue="8.80E-113"
                     /label="IE289_RS48415_Epimerization.1"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1401"
                     /protein_start="1096"
                     /score="369.5"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="PLPPMARLYAERGPGLDRLAQWLVLELPAAVDLPGLTAAVRAVLD
                     RHDVLRSRLTDDGLLVQPPGTPDAGGFVDRVDCPGDWGGEEWQTLLRAKAAEAVRHIDA
                     RAGRMLRLVWFPGAAGGPGRLLVVAHHLVVDGMSWRVLLPDLAAAWRQVQEGRPPALPR
                     VGTSLRRWLHALADEAARPGRVAEVPLWRDLLEAPVAPVGSRPLDPGRDLTSTTDTVRV
                     ELPADLTDAILTSVPAAYRSGADDVLLTALVLALARERRGLTDGTTVVRLEGHGRQEEL
                     VPGADLSRTAGWFTTVTPVRIDVS"
     CDS_motif       complement(43419..43469)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0012"
                     /evalue="5.00E-07"
                     /label="NRPS-E5"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1398"
                     /protein_start="1381"
                     /score="22.0"
                     /tool="antismash"
                     /translation="DLSRTAGWFTTVTPVRI"
     CDS_motif       complement(43887..43952)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0011"
                     /evalue="8.00E-11"
                     /label="NRPS-E2"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1242"
                     /protein_start="1220"
                     /score="34.1"
                     /tool="antismash"
                     /translation="LLVVAHHLVVDGMSWRVLLPDL"
     CDS_motif       complement(44166..44255)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0010"
                     /evalue="1.90E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1149"
                     /protein_start="1119"
                     /score="23.3"
                     /tool="antismash"
                     /translation="VLELPAAVDLPGLTAAVRAVLDRHDVLRSR"
     aSDomain        complement(44376..44579)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48415_PCP.1"
                     /evalue="6.10E-22"
                     /label="IE289_RS48415_PCP.1"
                     /locus_tag="IE289_RS48415"
                     /protein_end="1079"
                     /protein_start="1011"
                     /score="69.6"
                     /tool="antismash"
                     /translation="ESLLAAAFAEVLGLSHIGVDDDFFTLGGDSIRAIQVVGRARAGGL
                     ALTPRTVFECRTVAALAQAATRD"
     CDS_motif       complement(44913..44978)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0009"
                     /evalue="2.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="IE289_RS48415"
                     /protein_end="900"
                     /protein_start="878"
                     /score="35.5"
                     /tool="antismash"
                     /translation="FAGRADHQVKIRGFRVEPQEIE"
     aSDomain        complement(44943..46121)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48415_AMP-binding.1"
                     /evalue="8.50E-118"
                     /label="IE289_RS48415_AMP-binding.1"
                     /locus_tag="IE289_RS48415"
                     /protein_end="890"
                     /protein_start="497"
                     /score="385.4"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="LDRQARATPDAVAVTFEDTRVTYRELAERSGRLARLLTERGAGPE
                     RFVAVAVPRSLELVVALVAVLRAGAAYVPVDPDYPAARVEFMLADAGPALLLTVKDTAD
                     RLPRTDVPVVMVDDAPLTEEPVRSAPHRVDHPAYMIYTSGSTGRPKGAVVTHAAIVNRL
                     LWMQDRFRLDGSDRVLQKTSASFDVSVWEFFWPLITGATLVVARPDGHRDPDYLAEVIR
                     RAGVTTAHFVPSMLAEFVTEETAAACTGLRRVVCSGEALPAELAARFHRTFGVPLHNLY
                     GPTEAAVDVTAWQYRPGARTIPIGTPIWNTALYVLDSRLRPLPPGVFGDLYIAGAGLAR
                     GYHDRRALTAERFVACPFGEPGRRMYRTGDLARWNTDGELEFAGRADHQVKIR"
     CDS_motif       complement(45063..45152)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0008"
                     /evalue="3.20E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="IE289_RS48415"
                     /protein_end="850"
                     /protein_start="820"
                     /score="45.0"
                     /tool="antismash"
                     /translation="PPGVFGDLYIAGAGLARGYHDRRALTAERF"
     CDS_motif       complement(45258..45281)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0007"
                     /evalue="5.00E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="IE289_RS48415"
                     /protein_end="785"
                     /protein_start="777"
                     /score="4.0"
                     /tool="antismash"
                     /translation="YGPTEAAV"
     CDS_motif       complement(45654..45713)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0006"
                     /evalue="2.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="IE289_RS48415"
                     /protein_end="653"
                     /protein_start="633"
                     /score="29.0"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGRPKGAVVTH"
     CDS_motif       complement(45894..45932)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0005"
                     /evalue="1.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="IE289_RS48415"
                     /protein_end="573"
                     /protein_start="560"
                     /score="15.3"
                     /tool="antismash"
                     /translation="AVLRAGAAYVPVD"
     CDS_motif       complement(46458..46568)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0004"
                     /evalue="8.40E-11"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="IE289_RS48415"
                     /protein_end="385"
                     /protein_start="348"
                     /score="34.4"
                     /tool="antismash"
                     /translation="RERRRVLRHARHDISLIKRATGHAGDARSPFGAVVNV"
     aSDomain        complement(46608..47528)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48415_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.90E-55"
                     /label="IE289_RS48415_Condensation_Starter.1"
                     /locus_tag="IE289_RS48415"
                     /protein_end="335"
                     /protein_start="28"
                     /score="180.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILTDA"
                     /tool="antismash"
                     /translation="VTSAQEAMWLAQEFTPDVPNNVATLWDIDGDLDTALLAAALGAAV
                     AEADALKVNFRRDDHGLRPVARDLGAWEPFRLDVGDAADPADAARAVVADLVRRPFDLT
                     EDALLRIGSIRLGPGRHLLVLVFHHILTDAFGVLTLLSRRIAEIYRALRAGSALPEGAP
                     NPPGDAAAKDAVYRESQRFADAERFWRDYLAEDLPAARLPAGVRPGTDAPTGGPGYWDG
                     LTAPQGMATRTATVPAVELAAWEHASAAAGTSVPDLIASAATAFLGHMCGLSEQLLTIT
                     VNHRVGALRRSLGLLSNRVPLRSRVD"
     CDS_motif       complement(46620..46667)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0003"
                     /evalue="1.20E-02"
                     /label="C5_starter_265-294"
                     /locus_tag="IE289_RS48415"
                     /protein_end="331"
                     /protein_start="315"
                     /score="8.3"
                     /tool="antismash"
                     /translation="ALRRSLGLLSNRVPLR"
     CDS_motif       complement(47082..47150)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0002"
                     /evalue="3.80E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="IE289_RS48415"
                     /protein_end="177"
                     /protein_start="154"
                     /score="26.2"
                     /tool="antismash"
                     /translation="FHHILTDAFGVLTLLSRRIAEIY"
     CDS_motif       complement(47364..47471)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48415_0001"
                     /evalue="6.60E-11"
                     /label="C2_starter_024-063"
                     /locus_tag="IE289_RS48415"
                     /protein_end="83"
                     /protein_start="47"
                     /score="34.8"
                     /tool="antismash"
                     /translation="NNVATLWDIDGDLDTALLAAALGAAVAEADALKVNF"
     gene            complement(47804..48142)
                     /locus_tag="IE289_RS48420"
                     /old_locus_tag="GCM10010317_099560"
     CDS             complement(47804..48142)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962800.1"
                     /locus_tag="IE289_RS48420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099560"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_190174521.1"
                     /transl_table=11
                     /translation="MFVILFKSRLSEQAGEDYYAAEERMQERVRAIAGSDPVEVKHYTG
                     EDGERLAVMMWRDGETLDKWRCDPEHQVAQRLGRKHWYSAYELTVAEVVRTSAHDNESP
                     AAAAEGPR"
     gene            complement(48133..49509)
                     /locus_tag="IE289_RS48425"
                     /old_locus_tag="GCM10010317_099570"
     CDS             complement(48133..49509)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962801.1"
                     /locus_tag="IE289_RS48425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099570"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_190174522.1"
                     /sec_met_domain="DAO (E-value: 3.7e-09, bitscore: 27.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGNGTDRTDGNPETVIVGAGLVGVVTALYLAPRFGPVTLLEKRA
                     DPRRNSGGQRRSLVVMLSARGWRALSDLGVADAVRRICVPLHGRCGHLPDGRTRMTPYS
                     RDGQPIWAVERRRLHHILLDAAEATPGVRLRFGQRVGSVDLDEPAVVVEDRHGSHRLTC
                     RRVLGCDGAHSAARAALEARGTRAEVRTLDLAYQEIDVPAGRLDPTITHYWPSGKAMFA
                     AHPLPSGKLSGSLFMRLDGPAPSYAAARGGQDLYETFAAHFPELTGIIPDIAEQLATKA
                     VSTLTAVRCDRWVWRDTFALLGDSCHAMAPFMGHGMNCGFEDARVLVDCLDASADWAAG
                     LAAYEKSRTEDADAISRLSYRHYFTMAGPPREETAAEVLRGRLTVLFPDRFVPLYERCA
                     FTEESYASVLRDDQRLDRLVADLLARYGTELVSAPDDRLRACIPSPNPTTATPEDSVCS
                     "
     gene            complement(49576..50610)
                     /locus_tag="IE289_RS48430"
                     /old_locus_tag="GCM10010317_099580"
     CDS             complement(49576..50610)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354999.1"
                     /locus_tag="IE289_RS48430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099580"
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="WP_190174523.1"
                     /transl_table=11
                     /translation="MTTIAVIPGDGIGPEVIEPALDVLDALRLGTRTDVLDHVNAETYL
                     RTGTALTGADLDRIRSSQAALLGAVGDPRLSDTAYVRTVLTTLRLELDLYVNYRPARLL
                     HDRLSPLRDPARRAIDCVIVRENTEGLYSGIGGGTRTGTPQEIAIDVDLSTHQGVSRVL
                     EFAFSVARRSVCLVDKANAVRNGGQLWQRCWSEAVARHPHVETSHLYVDTAALRLATDP
                     TAFDVVVTNNSYGDILSDLTAALAGGLGVAASANLNPVTGQGLFEPVHGSAPDIAGTRT
                     ANPFGAILSVALLVEHLGRTEEADAVRRAVAAAVAAGRVTPDLGGSLSTKEAGTAVLTE
                     LRRP"
     gene            complement(50618..51364)
                     /locus_tag="IE289_RS48435"
                     /old_locus_tag="GCM10010317_099590"
     CDS             complement(50618..51364)
                     /NRPS_PKS="Domain: Thioesterase (21-238). E-value: 4.1e-44.
                     Score: 143.6. Matches aSDomain:
                     nrpspksdomains_IE289_RS48435_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.5"
                     /locus_tag="IE289_RS48435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099590"
                     /product="thioesterase II family protein"
                     /protein_id="WP_069930380.1"
                     /sec_met_domain="Thioesterase (E-value: 9.2e-44, bitscore:
                     141.3, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.1e-10, bitscore:
                     31.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRIRERGWVRSMIAGDPAGVRVVCFPHSGGSGVAFGEWSAAVPP
                     GVSLMAVQYPGRGDRFGEPPVDDVAAMAGCVAAELLRLPPGDHVLFGHSLGALVAYETA
                     LLLRDAGEEPRALCVSAALPPGSMTNRGVHLAPDDEFWSTLCALGGIEPAVAENAELRD
                     LLLPVIRSDLRAHATYRPRPGTRPLSCPVRSYHGAGDPLVEQDQLAGWASVTSGGFSGT
                     VRPGGHFHVTTDVAELVADVLSQGPK"
     aSDomain        complement(50651..51301)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48435_Thioesterase.1"
                     /evalue="4.10E-44"
                     /label="IE289_RS48435_Thioesterase.1"
                     /locus_tag="IE289_RS48435"
                     /protein_end="238"
                     /protein_start="21"
                     /score="143.6"
                     /tool="antismash"
                     /translation="RVVCFPHSGGSGVAFGEWSAAVPPGVSLMAVQYPGRGDRFGEPPV
                     DDVAAMAGCVAAELLRLPPGDHVLFGHSLGALVAYETALLLRDAGEEPRALCVSAALPP
                     GSMTNRGVHLAPDDEFWSTLCALGGIEPAVAENAELRDLLLPVIRSDLRAHATYRPRPG
                     TRPLSCPVRSYHGAGDPLVEQDQLAGWASVTSGGFSGTVRPGGHFHVTTDVAEL"
     CDS_motif       complement(51044..51115)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48435_0001"
                     /evalue="4.30E-07"
                     /label="NRPS-te1"
                     /locus_tag="IE289_RS48435"
                     /protein_end="107"
                     /protein_start="83"
                     /score="22.4"
                     /tool="antismash"
                     /translation="PPGDHVLFGHSLGALVAYETALLL"
     gene            51727..53322
                     /locus_tag="IE289_RS48440"
                     /old_locus_tag="GCM10010317_099600"
     CDS             51727..53322
                     /NRPS_PKS="Domain: AMP-binding (32-432). E-value: 2.9e-91.
                     Score: 298.0. Matches aSDomain:
                     nrpspksdomains_IE289_RS48440_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019548770.1"
                     /locus_tag="IE289_RS48440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_099600"
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase"
                     /protein_id="WP_190174524.1"
                     /sec_met_domain="AMP-binding (E-value: 5.6e-98, bitscore:
                     319.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDGFVHWPEQLAADLRRTGVWLGRPIGDLLHESCERNADRVAVV
                     CGERRMTYAELSRRADRLAGGLIGLGIRPLDRVVVHLPNIPEFVVLVFALLRAGAIPVL
                     ALPGHRRAEIAHLCAHSGAVAYVVKDEFGGFDFRTIAREIPSVPHVIVSGDAQEFVSLE
                     SLESLDAQDVALPRVDASDPALFLLSGGTTGLPKLIPRTHDDYEYVMRASAEAMRVGPE
                     VVYLAVNPVAHQAALACPGVFGSLLMGGKAVLTSSVRPDDVFSLIRREAVTVTTVVPSV
                     LRLWADSGRPPGELSRLLIQVGSAPLDPALARRAAQELGCRIQRWYGISEGLLTHTRLD
                     DPEEVAVNTDGRPMSPGDEVRIVDESGNPVPDGEAGEMQVRGPYTIRGYYRAPEENARS
                     FTPDGFFRTGDLVRRRPDGNIMIVGRIKDVINRAGEKVSAEEVERQLRTHPAVQDAAVI
                     GVADTVLGERTYAFVVLNEADVRPSAMKEFLRGRGLATYKIPDRLIPMPQLPRTPMGKV
                     DKKALRARIAASQR"
     aSDomain        51823..53022
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS48440_AMP-binding.1"
                     /evalue="2.90E-91"
                     /label="IE289_RS48440_AMP-binding.1"
                     /locus_tag="IE289_RS48440"
                     /protein_end="432"
                     /protein_start="32"
                     /score="298.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ESCERNADRVAVVCGERRMTYAELSRRADRLAGGLIGLGIRPLDR
                     VVVHLPNIPEFVVLVFALLRAGAIPVLALPGHRRAEIAHLCAHSGAVAYVVKDEFGGFD
                     FRTIAREIPSVPHVIVSGDAQEFVSLESLESLDAQDVALPRVDASDPALFLLSGGTTGL
                     PKLIPRTHDDYEYVMRASAEAMRVGPEVVYLAVNPVAHQAALACPGVFGSLLMGGKAVL
                     TSSVRPDDVFSLIRREAVTVTTVVPSVLRLWADSGRPPGELSRLLIQVGSAPLDPALAR
                     RAAQELGCRIQRWYGISEGLLTHTRLDDPEEVAVNTDGRPMSPGDEVRIVDESGNPVPD
                     GEAGEMQVRGPYTIRGYYRAPEENARSFTPDGFFRTGDLVRRRPDGNIMIVGRIKDVIN
                     R"
     CDS_motif       52837..52926
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS48440_0001"
                     /evalue="1.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="IE289_RS48440"
                     /protein_end="400"
                     /protein_start="370"
                     /score="20.3"
                     /tool="antismash"
                     /translation="PDGEAGEMQVRGPYTIRGYYRAPEENARSF"
     misc_feature    complement(53513..53526)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.08"
                     /tool="antismash"
     gene            53585..53779
                     /locus_tag="IE289_RS48445"
                     /old_locus_tag="GCM10010317_099610"
     CDS             53585..53779
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS48445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_099610"
                     /product="hypothetical protein"
                     /protein_id="WP_190174528.1"
                     /transl_table=11
                     /translation="MRHTCVRRARILNDSRRTRANGTLYQHKDSRWEAAGYVFAPPAAV
                     AGKDSVPRAFPSGETTATT"
     misc_feature    complement(53872..53887)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.33"
                     /tool="antismash"
ORIGIN
        1 cccacccgca ccaccgccca ccaccccctc ttccaaatct ccctcgcctt ccaaaacaac
       61 atctatccga ccttcgccct aggcgacata aagatcgact tcgagccgat atcgaccggc
      121 acagccaagt tcgaactgct cttcaacatc tcggaattac cccgcgacgg agaccatcct
      181 ctcggctatg tcgggtacgt cgaatacgcc accgacgtgt tcgaccggga gaccatcgag
      241 cagctgatca cccggttcaa aacagttctg cgcacagtgg tcgcaacccc ggacacaccc
      301 cttcgcgcca tcgacgtact ccttcccgac gagcgccacc aactcctcgg gtcgtcggac
      361 ccggccaccg aggacgccgc gattccggag ggctccatcc ccgtcctgtt cgaacagcag
      421 gccgcgcgga ctccggacgc gatcgcgatc tccagcggcg gcgaggacat cacgtatgac
      481 gagctcaatg tgcgcgccaa ccagatcgcg cacgagctgc tcgcgcacgg cgtacacctc
      541 gaatcagtgg tcgcggtcgc actcccccgc tcgccggaac tgatcgccgc catcctcggg
      601 atcctgaaag ccggcgccgc ctacctgccc atcgaccccg cctatcccag cctgcgcaac
      661 ggttccatcc tggccgacgg gcagccggct ctgatcctga cgagcagcgc cgtcgacacg
      721 cccgatgtgc tgcccgtcga aggaatcccc aggctgtacg tggcggacat cgtcggcggc
      781 gagcgcacga acccgtccca tgaccgactg tgcccggccc atctggcgta cgtcatgttc
      841 acgtccggat cggccggacg ccccaaggga gtcgcggtct cccatcgcag tgtcctgaac
      901 gatgcctggc acggctggcc ggagggaccc ggcgaccgga ttctcgtcca gtcgtcgatc
      961 gccttcgacg cgtcggtgta cgagatctgg ccggcgctcc tgcgcggcag gaccctcgtc
     1021 ccgctgccgg ctgacaggga gtcaccggcg caacgcctcc ggttcatcgc ggcgaacgag
     1081 atcgacacgc tgtgggccac cgccggcctg ttcgatctca tgtcgtcgga ggagctggac
     1141 gagctgtcgg gcctgcggac gctgcgctac ctggcgaccg gcggcgacaa ggtgccgacc
     1201 gcggcggtcg accgggttct gcgggcgaac agcgccatcc gggtcatcaa catctacggc
     1261 ccgaccgaga ccacggtgaa tgcgacgact catgtggtct gtgccgccac ccgtcagcgg
     1321 ttcgacgatc cggtggtccc catcggcgtc ccgatccgca atgcccgggt ctacgttctg
     1381 agcgctgagc tggatcccgt cgccaccggt gtcgtcggtg agctgtggat cgccggcgcg
     1441 ggcctggctc gtgggtattc cggccggccc gggccgaccg cggaacgttt tgtgccggac
     1501 ccctacggtc cggcgggttc gcggatgttc cgcaccggcg acctcgcgcg ctggacgcgc
     1561 gagggcgtgc tggtgttcgt gggccgggtc gacgaccaga cgaagatcag cgggttccgg
     1621 gtcgagcccg gtgagatcga ggcggtcctg ctggcgcacc cccaggtggc gcaggccgcg
     1681 gtcgtcgctc gcgacatcac cgggcagggc gtcaagcaac tggtcgccta tgtcgtccgg
     1741 aaccaggtgg catccgccga ccggcaggag agccgggaga tcgagctggt ggaccaatgg
     1801 cgggacacgt atgacgatct gtatcgcgga gaacaccacg ccggtgaccc tgccgacgcc
     1861 ggcttcggtg acgacttccg cgggtggaac agcagctaca ccgagacgcc gattccgttg
     1921 gccgagatgc gggagtggcg cgacgcgacc gtcgcgagga tccggtccct gcggccgtcc
     1981 aaggtgctgg agatcggagt gggcaccggg ctcctcctgg ctcgcctggc cccggaatgc
     2041 gaaacgtact acggcacgga cttctccgag tcggtgatcg acgggctccg gcagcacctc
     2101 gccgaggtgc cggcggactg ggcggaccgg gtcgaactgg tcgtccagcc ggccgatcaa
     2161 gtggatctgc tgccggagcg cgatttcgac accatcgtgc tgaactccgt cgtccagtac
     2221 ttcccgagcg tgcagtacct ggtggacgtc atcgagaagg cgatgggact gctggcgccc
     2281 ggcggcgcgc tgttcatcgg cgacatccgg aacaaggcac tgctgcggga attcgccacc
     2341 acggttcaga tcagccgact cggtcaccag gacgcagccg acctcgacga agccgagcac
     2401 ggcagaatcc gcagcaccat cgccacggcg atcgccatgg agaccgagct cgtcctgcat
     2461 ccggacttct tcgcggcact gggggacaaa ctgcccgcga tcggcgcggt cgacgtgcag
     2521 gtcaaacgtg gttggtacga caacgaactg agtcagtacc ggtacgacgt gacggtgcgc
     2581 aaggcgccgg ttcgggcaca atccctcgct gccgtccccc gtctgcggtg gagcgaagtg
     2641 ggcggcctcc aagagctgga acagcacctc cggacgcggc ggcccgagac cgtccggatc
     2701 gtcggtgtgc ctcaccaggc gctggcgacc gccgtgcgcg ccaccggcct tctccacgcc
     2761 gagcacaacg cgccggcggc cgacggcgag ctgcgcgaag agctctacac gctcggggag
     2821 cggctggggt actcgacggc ggtgacgtgg tcgcaggtcg caggacacct ggacgtcgta
     2881 cttgcggcac ccggtggtgg caacaccgtc cgcaccgatg tgtacgtgcc cggtttcgca
     2941 caggccggac cgctgacggt gtacggcaac gttccggtcg ccgaccaggc ggtggacctc
     3001 cgtgccttcg tgagcagcca gttgcccgcg tacatggtcc cctcgtcagt gatcttcctc
     3061 gacagtctgc cgctgaccgc caacggaaag ctgaaaaggg aggcgctgcc ggcgccggag
     3121 atcaccggca gctcgtcgcg gcgggcacgg aacgcgcacg aggaagtgct caccggcctc
     3181 ttctccgagg tgctgggcgt acccgacgtc gggatcgacg acggcttctt cgaactgggc
     3241 ggccactcgc tgctcgccac gaggctgctg tcccgcatcc gcaccgttct ccggatcgac
     3301 gtcccgatcc ggacggtgtt cgagtgcccc acggtggccg acctggcgcc gcgactgctc
     3361 ggcatggccc cggacggccg cgacgagacc tacgcaccgc tcatgaccat ccgctccggc
     3421 ggcgccgaac ggcccctttt ctgcctgcac ccggtgagcg gcgtcggctg gttctatctc
     3481 agcctggccc gctacatcga cgaccggccg atctacgcgc tacaggcgcc cggtctcgat
     3541 cccaccggcc ccgacctcat gccgacgtcg atggcccagc tcgtccagac ctatctggcc
     3601 aggatccggt cggtccagcc gcacgggccg tacaacctgc tcggctggtc gttcggcggc
     3661 ttcgccgcgc acgccatcgc cgccgagctc cgggcccgcg gcgaggaggt cgagctgctg
     3721 gcgatgatgg actgctatcc ggacaccgcc gtcgaagcgg ggaacctcga cggtcaggag
     3781 atccgcgagg ggttcgacca gttcctgcgc cacaggtact ccgatgccga ttcgctcgat
     3841 gtggacgcga tctccgacct cgtgacgggg atcagcgtgg agcacatcgc gatgctgacc
     3901 ggatacctgc cgccggaatt cgacggggcc gcggtcttct tcaaggcggg cgcggtcacg
     3961 gtggacggcg aggactcctc gcggctcgat cccgcaggcg cgtggcgggg ccacatccac
     4021 ggccccatga cggtccacgt cgttccgacc agccatcagg acatggacag gccggaatcc
     4081 atgcaggtgg tcggcaacgt actgaaacag actttccgca accggaccgc cggaggggac
     4141 gcgtgatcgg gaaagaacag aaccacaacc gctggttcgc cactgtgccg ccggacgact
     4201 gcgaccatct gctgctgtgc tttccctatt ccggctgcgg cgcctccatg taccgcctgt
     4261 ggcccaaccg catcggggac acggccgtgg taccgctgca actgccgggc cgggaaacgc
     4321 ggatgggcga agcccactac ggaacgtacg agaacctggc cgagcagatg accgccgagc
     4381 tgggcccggt cctggaccgc gacttcagtg tgttcgggca ttgcggggcg gcgctcgcgg
     4441 ccttcgaatt cgcgcggcga atggcgtccg gcgacaccag gtcaccgacc acctgtttcg
     4501 tgtcctcaca agtggcgccg gacgacgggc cgtacggccg gttcctcgac atgagcgagg
     4561 acgagctcag ggtcgtggtc gtgaacctgc tgggactggt tacgccgacg aagcgcttgg
     4621 tcgacttctt cgtcaaagtg ctggtggacg acctggcggc gaacaaggtc taccgtccgg
     4681 accggtccac gacggattcc ttcgagatcc gggcgatcgg ctggtccgcc gacgtggaga
     4741 tcccgcacgg gctgatggcc gggtgggcac ggtggggacg ctgcacctcg ctcgtgctgg
     4801 acggcgatca ccaggcgttc gtgaaggcgc ccggccacct tctcgacgct ctccaagccg
     4861 gtgtcgaagc cgacacgcgg gcgctgtgac atggcggacc ggacagtgcg catacccgcc
     4921 aggtacaacg gcccgcccgg cacggcgaac ggcggctatg cctgcggcac gttcgcgaag
     4981 ccggccgcgg accaccaacg cccaccggtc gccgtggcgc tgcttgtggc gccacggctc
     5041 gaccacgccc tggagttccg tcccggatca cggcgctccc agatctggga cggcgaccgg
     5101 ctgatcgcga ccacgaccac cgcctcggcg gagttccccg ccgtggaagc ggtgtcgctc
     5161 caggcggcgg ccgatgcgag cggacgttac cgggggcgtg tgggtcatcc gtttccgacc
     5221 tgcttcgtct gtggagtgga ccgtgaaccg gcggacggct tcccggtggc gccgggcgag
     5281 gtccccggtg cgcccggcat cgtggcgtgt ccctggacgc cgacggcggc ggcgtccgat
     5341 cggcccgagc tggtatggag tgtcctggac tgccccggcg ggtggaccac ggacccggtc
     5401 tgggagccga tggtgctcac ccgcatgacc gcggtcctgc gcaggccgcc ccgcccgctg
     5461 gcaccccatg tggtggtcgc gcgccgatgg cgtcggcaag gccgcaccgc gtcggtcggc
     5521 accgccttgt acgacgaccg tggcgagctg gtggccaagg cgacggccat gtggaccgct
     5581 gtcggcgtcc aggaaccggc tgatggccga gagcagggag acctcgatga ggatgagtga
     5641 gcgaaccgcg ccggcggctt ccacggatct ggactcgctg gatctcatgg atccgcgcct
     5701 gtacggctcc ggtgacccgc acacgatctg gaccgcgctg cgtgagcgcg ccccgttgca
     5761 cctccagtcg ttgccggacg gccgccgatt ctggtcggtc accaaatacc atgacgtccg
     5821 cgaagtgctg cgggaccaca ccaggttcac ctcgagccgg gggaccttgc tgtcggtcct
     5881 cggcagtcgc gacccggccg gcggcaagat gatggcggcc agcgacccgc cggtgcacac
     5941 gatgctgcac gagccgatcg ccaagctcct gtccaggagg gcgctggagc cgttcgtccc
     6001 ggaagtgagg cgggtggccc accgcctgct cgagcgactg gccgacggcc cccgggatct
     6061 ggccgaactc gcggcgggtt tcccgatggc gttcaccggc acgttgatgg gcattccgga
     6121 gcaggactgg gcgcggctga ccgtgctcac caccgcggcc atcgcaccgg aagaccccga
     6181 cttccggctg gggaacgggc tcaacacctt ggcgacggcg catcacgagc tgttctcgta
     6241 cttctcccgc cggactcgcc gcactacccg ggaagacggc ctgatcggcg cgctgctcgg
     6301 cctggaggtg ggcgggcgca gactgcgcca cgacgagctg gtctacaact gctacagcct
     6361 gctgctgggc gccaacgtca ccacaccgca cgccgtcacg caaacggtgc tggcgttcat
     6421 cgagaaccct gcggagtacc gcagactggt cgacgatccg cgattggtgc ccggcgcggt
     6481 ggaggagggc ctgcgctggt cctcgccggc cagtcacttc ctgcgccacg cgacccagga
     6541 cacgacgttg cgcggccgac aggtgcgtga gggcgacgcg gtggtgactt ggctgggttc
     6601 ggcgaaccgg gacgaggagg tcttctccga gcccttccgg ttccacgtga cccgatcacc
     6661 gaacccccac gtcgcgttcg gtttcgggcc gcaccactgc gtcggggccg ccttggcgcg
     6721 gatggcgctg aacgcgctgt tcgccgagat cgccggctcg gtggagcgat tcgacctcgc
     6781 cggcccggtg gagcatctgg cgtccaactt cgcggccggc atcaagcaca tgccggtggt
     6841 cacgaagttg cgcaccacct agtgtcgcgt gaacaaagtc ctcggacgac gcatcatgcg
     6901 catcacgtgc acgaacgcag tgcctctacg actgcgaaga tgtcggtgta ggagatgtag
     6961 aggctgttga acccgaaccg cagcagctcc ggaggacgcg cgtcgccgat gatcccgtgc
     7021 ttgttcaagg cccgcatgat ccgctccgcc tccggatggc acagcgtcac ctggcttccg
     7081 cgctgatcgc cacggcgcgg cgtgaccagt tcgaatccgc gcccggccag gtgggcgtcg
     7141 accgcctcga tgaagaaatt cccgagcgcc acgttcttct cgcggaccgc tgccatctcc
     7201 acgtcgtcga agacgtcgag tgccgcgtcc agtgccagca tggacaagat gttcggagag
     7261 ccgacccgca gccgtccgat tccggtcgtg ggctcgtagt cgagcaccat cgcgaacggt
     7321 tcggcgtgtc cgtgccagcc gcacagtggc tgatcgatgt caccgtgatg gcggctggcg
     7381 gcgtagacga accccggggc gccggggccg cccgacagga atttgtagga gcaccccacc
     7441 gcgaagtcca cgccgtccgc gtcgagggtc agtgggaggg cgccgacggc gtgacagagg
     7501 tcccagacga cgagcgcgcc gacgtcgtgc gccgcgtccg tgaccgcgcg gacgtcccag
     7561 agttcgccgg tgcggaagtc gacggccccc gctgtggcga ccgcgaccct ctcacccagc
     7621 cggcggaggg tggatgccat gtcgggcatg ggtacccggc ggacctccag cccgagaatg
     7681 cgggcgaccg aagtggccag gtagtggttc gtggggaaac cgccttcttc gaccaggagc
     7741 agtcggcgat ccggacgcaa ccgggccgcg gccgtcagca cgttgaacag atgtaccgag
     7801 gtcgaatcac ccacgacggt ctggccggcc cgcgcaccga gcaggcgccc gacgcggtcg
     7861 ccgacccgca gcggcgcgtc ccaccagccg tcatcggtcc atacgttgat gaggtgccgg
     7921 ccccagttct cgacgacggc cgtctggacc gccgccggca cgcccacgga cagggcgccg
     7981 agggaattgc cgtccaggta caccacgccc tccggcaacg aatacctcgt acgcaccgcg
     8041 gccaggggat cggtccggtc gagtcgttcg gcggtttccc ggctgggggt gggcatggct
     8101 gtctccatcc aagtatccgt gacgggtctc ccggtgtccg ggcacagtcc cggcgtcgcc
     8161 aggaagcggt cacttcccgt ggagccgacg caggtacgtg tgcatcgggg gcagggtgtc
     8221 gagcagctcg tcccgtcgcc gttggacctg cgcgaacacc gcttcggcgg atttgacgga
     8281 ctccggtcgg tagtcgagcg gcgtggggtc gtgttccggc atcatgccga ggccggcgaa
     8341 cacgcagtag tagttggcgt tgctccagaa gttccggaac tcggcctcga agtttccgta
     8401 gtaggtgctc tcgtcggtca ccggtaggtc caccccgagg ccggccttgt acatctcgac
     8461 cttgcggacg aactccggcg ccagctccag ctccttgcac gcccgccaga acggcgtgtc
     8521 gtcgcgcggc gcgaagctga aatggccctg gatgaagtct ctcgtgtcgt cgaacatcgc
     8581 ctcgatctcg ctgttgaagc ttttcgtcag catcggatcg aagcgcttgt ccgggaagtg
     8641 tttcaccagc tggtagagag cggcgtaggt gaagtagatc ccggtggact ccagcggttc
     8701 cagaaagcac gacgaaagac cgattcccac acagttcttc acccatgccc gccgattccg
     8761 gccgacccgg aaccggacgt ggttcatcgg atgcgtgtcc ggggagatgc cccacatctg
     8821 gcagaactcc cgggtggcct cctcctgcga ggtgaaccgg ctggagtaca cgtacccggt
     8881 gccgaaacgg ccgagcatcg gtatcttcca cgcccagccg gagctcatcg ctatcgcgga
     8941 ggtgtacggc tcgacgccgt gctcttcgtc gtcatgctcc agcctggtcg ccaccgcccg
     9001 gtcgttgagc aggtggtcgc tcatgtccag gaacggctcc ttcatcacct ggttgatcag
     9061 gaggctgcgg aaaccggagc agtcgatgaa cagatccgcc tccagccttc gccctgattc
     9121 ggtggtgacg gcgacgaggt ggccgcgctg atcggtctca gccgcgatga acttgtcctc
     9181 gatgtgcgtc gccccctgcc tggcggtggc gaacctgcgc aggaagtccg cgacgaggtc
     9241 ggcgtcgaaa tgccaggcgt aactagccac gcggcggccg tcggggaagc ggggggacag
     9301 cttccggtcg aacagcgccg gctgcgggta gcaggcgcgg tcgaacggct catcggtcat
     9361 tccgttgagc ttctggtacg tccagtagtg cgacagcggc aggttgtcgt ggttgggaag
     9421 caggccgaag aggtggtcga actgatcccc gtactgcccg tagggccgtg ggcgggccgt
     9481 accggtgccc ggagtgcgcc agttgatgaa tctgatgccc atcttgtaac tggcgttgca
     9541 ctccggcatc cactcctctt cggtcaggcc gaggtagtcg aagaacaccc gctggagatt
     9601 ggggatcgtg gcctcgccga cgccgatctt cgggatggcc ggcgcttcca gcacggtgat
     9661 ccggacggtc gagccgagcg ctttgccgag gtaggaagcg gtcatccagc ctgccgtgcc
     9721 gcctccgagc acgagtatct tcttgatcag gttgtcgctc atgtgcgtcc aatgtctcgg
     9781 tgggatcgaa cggagtcgcc tgccgttctg ctggatgccc gtccgggcag ccccagctga
     9841 cggagcaccg cggcgcccag gtcactggcg ggatcgtcga ggtcgaaggt gatgtcgaag
     9901 tggttccggt gcgggatcac cagatcgcgg acggcggccg aacgaggcgt ggcggcctcg
     9961 acgagctcgc ggtgctgacg cgcgaactcg gcggtctcgg cgccgccgcg cgccacgacc
    10021 agcggcggca gccggtccgg gaggcggcgg atcgggctga gccgggccgc cgcctcggcg
    10081 tcgagcccca gcggttcgtt gacgtaggtg aggcggatcg gctcgaggtc gtacacgccg
    10141 ctgagcagga ccgctccagc gatcacgtcc gccggacggg tgccctcggg catccagccg
    10201 tcgagcagcg ccatcagcgc cagatgagcg ccggcgctgc ttccggcgag cacgatccgc
    10261 tcgctgtcga ccccgaggtc cccggcgtgc tccacgagcc accagacggc gcgtcgtacc
    10321 tgatcgacga tctcgtcgag ccggtaccgc ggagccagcc cgtagccgat ggccgcgaac
    10381 gcgatgcccg ccggcacgag ccggcgcgcc ggaaaggagg agtcgtcctt gccgagttcc
    10441 cgccagtagc cgccgtgcac gaacaccagt agcggcgcct gtgggccgcg cgccggaaag
    10501 aagtcgaggc tttcgcaggg cagtgagccg tacgggatgc cggcgttgac cggcagctcg
    10561 gtcctcgttc gcgcgctccg cgtcgtgtac gaggtgagaa aggcagacag gtcgtccaca
    10621 caggagctcg gagaatactg acgatcaagc tcggtctggt tgtaccggcc gtaaacgagg
    10681 aaactcaatg atcgtcccca tatcaccggg agataggcat cagatggcgg tgcgggcgcc
    10741 caacagctcc gggaagaatc ggtgttcggc caccttgtgc agccagctga cgccggaggt
    10801 tccgccggtg cctggcttgt ggccgagtat gcgttccacg gtcagcagat gggtgtagcg
    10861 ccattgcgcg tgctgatggt tgaggtcaca cagtgcttcg gccagggcgt gaacgtccgg
    10921 atgctcgcgg tgcgaccggt agacccgcgc ccaggcctgt tcaaccgcgg cgtgcggctg
    10981 gtacggctcg gcgaagtccc gttcgacgca gtgggccggg acgcccaggc cgcggcgacg
    11041 gagcacaccg agcgccgcgt cgtacaggct cggtgcccgc agcgcggcca tgacctgctc
    11101 gtacacccag cccaccggcc ggtacggttc taccatccgg ggagccttgt tgccgagcgc
    11161 gaactcgagt tgccggtaca tgtaggactg tatgcccgac gccgaaccca gctcgtcgcg
    11221 gaaggccgcg aactccgccg gcgtgatggt gctcaccggc tcccacgtcg tcgtgagtac
    11281 ccgctggacg tgcccggcgc gtcgtagata ccgaagggcc tcgtcgaggt cgtccgcgaa
    11341 caacaggtct cgtatccggt tgacctcggt gaacagcagt ttgaagagca gttcctggat
    11401 ctggccggtg atgtagaacg acagctcggc gggttcgctg gtgcgcgggt gctggagacc
    11461 gagcaggacg tccacgtggt ggtacccgat gtaggccgtg ctctcggagc cgttcgtgac
    11521 atcgaaatcg agcatcggct cgccgccggt gctctccgcc cgccgccgtc gttcttcctc
    11581 ggtcagcggg gtgtaggaga gcggggccgt acgctccagc tccattgcga catcaactcc
    11641 catcaggtgg cacccggcag tgccggagct cgaagggccg gcgagaggga caaagccgca
    11701 gcaggaaccg aacgcggacg gcattcgagg tccatggccg gagcatcgca cgctgacgcg
    11761 gatactgatc agcaatcttt cggttctcat tcatgggcgg attcatgggc gaactgccgg
    11821 tcttccccac tcctcttgcc gcctattcgg gggcgccggc ggctatcagc ccggcaagct
    11881 cggagatcgt cggacaagcg tagaaatcct gcgggtcgat ctcgacgccc gtgcggtcgc
    11941 tgatctccac gatgatccgg acggccatca gcgaatgacc gccgagctcg aagaagtcgt
    12001 cgtcgacgcc gacgggggac gtctgggtga gatcgcccca catctcggcg agccactgtt
    12061 ccaggggatt gccggggcca cggtagtccg agctcaggtc cccccggccc ggcggcgcgt
    12121 acgcggtcag cgcgtcccgg tcgaccttgc cgttgaccgt caggggcagg gcttcgagcc
    12181 acaccaggac agccgggatc atgtacgggg ggacaagggt ttccatgtgc ttgcgcaggt
    12241 gctcggagac cagcggttcg tcggcgacgt agaacccgac gagggagcgc tcgtctcccg
    12301 acgacgtggc gacgatcgcg gcgtccgcca cgtccgggtg cacgcgcagg gcgtgttcca
    12361 cgtcgcccgg ttcgatccgg aagccgcgga tcttgacctg ccggtcctcc cgtccatgga
    12421 agtcgagcgc accgtcctcg ccgcgagatc cgagatcccc ggtgcggtac atgcgatccc
    12481 ccggtacccg ggagaacggg ttcgccacga accgctgagc ggtcagcgcc ggatcgttga
    12541 gatagccgcg cgccagaccg gcgccggcgg cgtggatgcg gcccgcctgc ccgtccggcg
    12601 ctgtcccgac ggcgtcgtcg agcacgtaga ccgaggtgcc gtcgatcgcc ggtccgatcg
    12661 gcacccgcgg cgccgtgacc ggttcggcca gaggtgcgca gcaggtgaac gtggtgttct
    12721 cggtggggcc gtagccgttg atcagcgtcg tgccggcgag ttccgccatg gcggcgttga
    12781 ccgactccac cgacagcacg tcgccgccgg caagcaggaa cctgaggcca cgcagccgtg
    12841 ccacgagccc tgacgcgacc aggtggtgga acaacccggc ggtcagccac aggatcgtga
    12901 cgccctcgcc gcgcaccagg tcggcgagtg ctcccagggg gagttgttct tccggcgcga
    12961 ccaccagctt gccgccgttg agcaggggcc cccagatctc cagggtcgag gcgtcgaagg
    13021 cgatgggggc cagttgcagg aagacgtcgt cgggcccgat cggcagataa ccggccccga
    13081 caaccagccg ttcgatcgcc cggtgcggca ccatgacgcc cttcggcttc ccggccgatc
    13141 cggaggtgta cgcgatgtag gccgtgctct ccggtgaagt acgggtcacc gggcgcgtcg
    13201 tcggccgtcg cgaagcgcac gccgacagtt ccggcagcgg acaccacggc ggacccccgt
    13261 ccgtggcgga cggctccccc tcgtcggtga tgaccagcgc cggacgggcg tcgagcagaa
    13321 ccgtcgcccg gcgctccgcc ggcaggcggt ggtccagcgc cagatacact ccgcccgcct
    13381 tgagaacggc caccagggtg acgatcagat cggtcgagcg gcgcatcagc agcgccactg
    13441 ggacctcgac gtccacccct cgggcgcgca gttcgtgagc cagctgattc gcccggcggt
    13501 ccagctcggc gtaggtgagc tcgccgccgg cgccgcggac cgcgatcgcc tccggacgct
    13561 tcgccgcctg ctgctcgaag acctcgacga cagatgccgc tgtgccggac atccagaatc
    13621 cctttctcgt gcgacgtact ccgcgagacg ctcgccggtg cgggcggtga ggaagttggc
    13681 gggctccttc ttggtgacgc ccgcacccgg ccggccggag accaggagag cgcgaaagct
    13741 cagtcagtcg ctgctgtcgg tcgaatgttg tggttgaacc ggaacaggtt gtgcggatcg
    13801 tgcagcgtct ttacgcgtcg cagccgctcg aagtcctcgg ccgcgaagag ttcccgcacc
    13861 tgctcctggc ggaccggggc gccgtcgttg tagacggagt tgaggctgcg gccgacggtc
    13921 cactgcttca gggcgtcgta gacgcgctgg tggaccggcc gggctgcggt ggacggcgcg
    13981 gccgtgccgc cggtcatcac tcgcagcatg tacgcggcgt cacggccccc gaccacgccc
    14041 ggatcggtgg gccggcggcc gaaggccccg ccgaggtgac ggatgtcgac gatgcagggg
    14101 acggtcgcat cgggtccggc cacctccacg acggtccgca gggccgtggg atcgagttcg
    14161 ctcagcagga cgttcccgcc gaagtaggca tgcgggacgt gcgggtcctg gtagatggtg
    14221 ccgacctccg tgtacggcat ctcccggacg gtgtcgatca gacgcgggcc gagggcgcgc
    14281 aggggcgcca cgagccgttc gccctcctcg gcggagcccg tgaaggcgat ccggacgtgt
    14341 gcgacgtagc gtccgcgcag cggctcgggg acggacggca acggtgggaa ggtcatgagg
    14401 ccgatcgagg aggtgagttc ctcgggcagc gtgagggtcc acgcgcggta ggcgtgcagc
    14461 aggtcgacgg ggtggtccgc ggcgaagtgg aggccgccgc cgtagagcct ggtcaccggc
    14521 acgagggcgg tctcgatggc ggtgacggcg ccgaagttgc cgccgccacc gcgcagcgcc
    14581 cagaacaggt cggtgtcgga tccggccgtg acgtggcgca gcgcgccgtc ggcggtgacg
    14641 atgtcgatgg cgcggacgta gtcgctggcg taaccggtcc ggcggccgag caggccgaca
    14701 ccgccgccga ggaggtagcc gacgacgccg atgtgcggag ctgagccgtt gacaggggcc
    14761 agaccgtacg gggcggcccg ctcgatgacc tctccccaca gcacgccggc ctgggctctg
    14821 acggttccgc cctccgcgtc caccacgacg gccttcatcc ggcgggtggt gatgagtacg
    14881 ccctcaccgt ccagggccgt gacgatgccg tgtccggtgg actgcacggc gacgggcagc
    14941 ctccgctcgg cggcgaagcg gaccgcggcg cgcacgtcct cggggcgggt ggcgccgacg
    15001 acgacggcgg gccggtgccg gaagccggtc tggaaaccgg tccgttcctc gtcgtaccct
    15061 cggctgccgg gcagcaggac gggtcctcgc acctccgcgg ccagcgtctc cacgtccgcg
    15121 ctcatccgtt gttctcctcc cgtggacggc gggccgccgt cccgtgtgtg ccgctcggtc
    15181 gactggtccg ctaccgcagg tacgagttgt cctgcaccca gtggaagcca cggccgacca
    15241 gcgggaaggt gccgagatcg cggcggcgca gatgcaggcg gaggtggtag ccgtcggcgt
    15301 cgccctccag gatcaggcgg tcgtcggccg ggcgctcgaa ggtgaacgtc acttgccact
    15361 tggggtcggc catcttggtc agcgcgaccg aacgggcgtt catgtcgatc gccgccatgc
    15421 aggggtcgag cgagtcgtcc atgtgctgga tggccacggc gtcgacggag tccacgacga
    15481 ctcggcgcca gcgctggccg tcggtcgtca tgggcgggtg ccgctcgccg tcgatggaga
    15541 agtcggtgac gtcccagacg ccgtacaact cgggcttttc ccgtccgccc ccgtggttct
    15601 tccagaacga ccagtcgttg cgcagctgtg cgccgagcag ccagagcccc gccccggcct
    15661 gcagtgcggt ggcgatccgg ttcgcccggc gggagcggaa gaggtccgcg ggggcggccg
    15721 cggggaccgg gcgctccgtg agcagggctt cggccaggcg aggcgtgtgc ggggccagca
    15781 gaagcaagct gagcaggagg aggtggaagg agtggacctt gacggggacg tcgaaggtca
    15841 tgttgaggag aagcacctgg gccatctccg cggccgacac cagcgcgccc agcgacgccg
    15901 tgcgcggaac gatgagcagc agcccgcccg cgatctccgc acagccgagc agcatctggt
    15961 acggcttcga ggaccccgtc tgcgcccaca gcaggcccat cgggctgagg tcgccgagcg
    16021 gctcgacgag cttggacggc ggcagctgga actggagcgg gacggccttg gccgcgccgt
    16081 aagagaacat ctgccccgcg aggcagaaac gggcggccag gcggacccac ttgtccagcg
    16141 ccgcgtagtc cgtccggttc cggtccagca cggaccagac cggggtggcc gcggcggcgc
    16201 ccgcgagcca gcagagctgc cccgcccagg tgtgcgggtc gtcgccgccg tcgaagcggt
    16261 cacccagctc cctgccgagg acccggacgg acatccagtt ccgcaccggg cgtacctccc
    16321 agagcttcgc ccaggagtcg gccgcttcct ggagacgccc cattccgccc ccgcgcaggg
    16381 ccagatagac ctgaggggag gtcaggcagt acaggccggc gtaggcgaaa ccgaaccggt
    16441 aggcggcgcg ggcggccccg gtccagggag gcggggccgg ggaggcgccg gccgacggga
    16501 ccacccgtcg ggccgcccgg ccggccggtg aggacgcgac ggtccgcagc cacttgccta
    16561 ctcgcacctt catcgttcat caccttcgca agggccgtct tcggtggtcg cggtcagcta
    16621 cggcggaagc gtccgagcca ggcgtgcacg tcgaggagtt cggacgtggt cgggatgatg
    16681 ccccgtatgt gggtctcgtc gatcgactcc accgtccagc cgtcggcgaa gccgtggcgc
    16741 aagtggtcgg cggagcgctt gaggccaggc ggctcgtcgt tgtccggaag cggcgccggt
    16801 atctcctcga tggcctcggc gagccgcgcc tgcatctccg cggacccccg gtcgctgatc
    16861 gagaggatgt gcgccaccgc ccccgggcgg caggcccggt gcagggccgc cgcgtaggaa
    16921 cgcagagtgt cgccctcgaa ggtgtgggcg aggccggagt cgatcacggt gtcgaagcgc
    16981 ccttcccagc ccttgaggtc gagggcgtcg gcgacttcga agacggcgtc gagtccgcgt
    17041 gccccggcct tgtcccgggc gagggagatc gccgtcgggg acaggtccag ccctgtcacc
    17101 gcgtacccct tgcccgccag gtggagggcg tcctcaccgg tgccgcagcc cgcgtcgagg
    17161 accgcgccgc cgatgagtcc cgcttcctca agggcgacgt aggcgggctg gggcgccccg
    17221 atgtcccacg gcgggcgttt gccgaaaggg ctctccccgc ggtaaacggc gtcgaacacc
    17281 tcggtcatcg gggcgggtcc gtcgggtgcg gcgacaggtt cagtcatggc tgccatgatt
    17341 gcgtcgcccc ccggtgcgtc ctcggtctct tgcggacttc tgtcagggag gcaccgcccg
    17401 ccggtcagcg cgagccgtac ttgcggaccg cgagcggggc gaacaccgcg atcaggccga
    17461 ccgaccaggc cacggtctgg aggacgtagc tcgtcgccgg gcccccggtg aacagtgcgc
    17521 gcagggcgtt cacggccgcc gtcatggggc tgtgggcagc gtacgcctgg agccagcccg
    17581 gcatcgtgtc ggtcggtacg aacgccgagg agatcagtgt gaacgggaag atccacacgc
    17641 cgccgaccgc ctgggcggct tccgcgttgc gcaccgacag cccgaggtag gcggcgaacc
    17701 acgacaccgc gtagccgaac agcagcaaca gcagcaggcc ggccagcgcg ggcaggaggc
    17761 cgttgtggaa ccggaagccg accagcacgc cgactcccac ggtcacacag gccacgccga
    17821 cgttgcggaa gatctccgac agcgtgcgtc cgatgagcac ggcggtacgg ctcatcggca
    17881 tcgagcggaa gcggtccatg aggccctcgc gcatctcggc ggcgaccccg atggtcgtgc
    17941 cggcggcgga gccgtagagc gccatctgga cgaggacgcc gggcagcagg aactgggcgt
    18001 agcgttcgcc gccgacgtcc atggcgccgc cgaagacgta cgtgaacagc aggatgaaca
    18061 tcaccggctg gaccagcgag aacatcacca gatcggggct gcgcagcacg tgccgcacgt
    18121 tgcgcagggt catctgccac acgtcggaga gccaccaccc gagggtgttc cgcgactgcg
    18181 tgtacgacgt gccgctctcc cgtgtcaggg tggtggaggt catgtgcgcc cggtttcctt
    18241 cccgatgttt cgctggtcga cgccgtgatc ggcggaccgg ccggtcacgg cgagaaaaac
    18301 gtcgtcgaga gtgggtcggc ggagcgccac gtcaccgatc gcgatccccg actccctgag
    18361 caggtggagc aggtcgggca gggtgccgcc gtcgggcagc ggggcgtgga ccaccatctt
    18421 ctgcgggtcg gcgaccgggt cggcgcccag ccgctcccgc aggagccgca ccgtctgttc
    18481 catgccttcg ccgtccaaca gcgtgatgcc gacccggtcc tgacccacct gagccttcag
    18541 ctcgtccggg gtgccgccgg cgatgaccct gccccggtcg atgaccgaca gggagtcggc
    18601 cagttggtcc gcctcctcca ggtactgcgt ggtgagcagt acggtcgtgc cctccgcgac
    18661 cagttcgcgc acgagccgcc acacctccat gcggctgcgc ggatcgaggc cggtggtcgg
    18721 ctcgtcgagg aagatgagcc tgggccgcgc catgaggctg gcggcgacgt cgagccggcg
    18781 ccgcattccg ccggagtagg tcctgggctg ccggtcggcc gcgtcgtcca ggccgaagcg
    18841 ttccagcagt tcgctcgcgc gggcccggca gtcggacttc gacagccgga acagcctgcc
    18901 gatcatgtgc aggttctcgc gcccggtgag cagttcgtcg acggcggcgt actggccggt
    18961 gaggccgatg accgaccgga tccgcccggg gtcgtcacgc acgtccacgc cgaacacctc
    19021 ggccgctccc tcgtccggtc tgatgagggt ggccaggacc cggacggtgg tggtcttgcc
    19081 ggcgccgttg gggccgagca ggccgtgcac cgtgccctcg gacaccgtga ggtcgaggtg
    19141 gtcgagtgcg gtgagcgagc cgaaacgctt gcacagtccg gccgttctga tcgctgctgg
    19201 catctgccgt ggttcctttc cggatccgac gcaaccctga attgagtggt ggcggggcaa
    19261 ccggttcagc ggcgcacagc gccgagcaac gccgacatgt ggatggcgtc ggcggccgcg
    19321 gcgcccgccg cggccgacac ggtgaccgac tgcttccagc ggctggtcag gtccccggcc
    19381 gcgtacaggc ccggaacgct ggtgcactgg gaggcgtcga cgccgatgaa gccggcgtcg
    19441 tcgaccgtca gcttcagctc ttcggcggtc cgcctgacta cgggttgctg ccgctgtcgt
    19501 ggcgtccaga ccagtgtctc ccgctccagg acccggccgt cgtccaactc gacggcgtac
    19561 aaagcccctt ggcggtgatg caggcggcgg accgttcccg tgacgacctc gcccccgctg
    19621 ctccgcgccg tcgcgcgagc ggtctccagg ccgggcatgg actcctggca gatcgcgatg
    19681 gtgtcctcgc tccaggcgag gaaggccacg gccgacagtc ccgcgagttc cgcgttgtcg
    19741 gcgacggtcg cccagcgccc gccggcgttc tcctcgccga ggcagaacgg acagtggatc
    19801 acgctgcggc cccagcactc cgcgaaaccg tccacgtcgg ccgggtggac gtccacgaca
    19861 ccggtggcga gcagaacggt tcgggcctcg acggtctcac cgccgccgac ggcgacccgg
    19921 aagcctccgc ccggagcggg ggtcacgctt tcggcgtcgg cctccagccg ctcgacggtc
    19981 gcgtaccggg agagttcccg ccaggcgcgc gcccggaact cgccgggcgt gacgccgtcc
    20041 attccgacat ggccgtgaac acccgccgac gcgctgttgc gcggtgcccg agggctgtcc
    20101 acgacggtca ccgggtgccg gtatctggcc aggctgagcg ccgcggtgag cccggcgggg
    20161 ccggctccca cgatcacggt ggtgtggtcg gcgtgcgagg acatcggtct gatcccttcc
    20221 gtcgggcggc gtgagcgggg tccgtccacc gtgggtgcgg tccggcaggc gcgcggtggg
    20281 gaacgccgga acgggctgtc agcgggcgga ggccgtcggc ccgcattgtg gtcgccgccg
    20341 cggtgcggga gaggtacggg cgaaagaggt gagccagaca gtcgtgcgcg tacggcggtg
    20401 cgagcgacgt cgactttcgg cccggcgcag gccggccacg gtcaacgccc ccgccgcccc
    20461 cgccccctgt caccaggcgg ggggcgggcg ggccgcgtcg tgtcaggcgc cgacgtactg
    20521 tgcgaggtgc tcgcccgtga gggtggggcg gtcggcgacg agctcggcgg gcgtgccctc
    20581 gaagacgatc ttgccgccgt cgtggccggc gccggggccg aggtcgatga tccagtcggc
    20641 gtgcgccatg accgcctggt ggtgctccac gacgatgacc gtcttgccgg cgtccaccaa
    20701 ccggtcgagc agggcgagca gttgctcgac gtcggccagg tgcaggccgc tggtcggctc
    20761 gtcgaggatg tagacgctgc ccgttccggc catgtgaccg gcgagcttca gccgttgccg
    20821 ctctccgccg gagagggtgg tgagcggctg gccgaggctg aggtagccca ggccgacctc
    20881 ggcgagccgg tcgaggacgg catacgcggc cggcgtccgt gcctcaccgc tgcggaagaa
    20941 ctcggcggcc tcggccaccg gcatcgcgaa cacctcgctg atgtcccgac cgccgagccg
    21001 gtactggagc accgaggcct ggaaccgctt gccctcgcac tcctcgcagg tggtggcgac
    21061 gccggccatg atcgccaggt cggtgtagat gacaccggcg cccttgcaag tcgggcaggc
    21121 gccctcggaa ttggggctga acagtgcggg cttgaccccg ttgaccttgg cgaacgtctt
    21181 gcggatcggt tcgagcatgc cggtgtaggt ggccgggttg ctgcgccggg agcccttgat
    21241 gggcgactgg tccaccgtga cgacgccgtc gcggcccgct accgagccgt ggatcaggga
    21301 actcttgccg gagcccgcga cgccggtgag cacggtgagc acgccgagcg ggatgtccac
    21361 gtcgacgtcg cgcaggttgt gggcgttcgc gccgcgcacc tccagcacac cggaccgctc
    21421 gcgcacggac ggcttcagcg aggcccggtc gtccaggtgc cgtccggtga cggtgccgct
    21481 ggcccgcagt ccctcgacgg tgccctcgaa gacgacttcg ccgcccttgg tgccggcgtg
    21541 cggtcccagg tcgacgacgt ggtcggcgat cacgatcgtc tccggcttgt gctccacgac
    21601 cagcacggtg ttgcccttgt cgcgcagtcg cagcagcagg tcgttcatcc gctggatgtc
    21661 gtgcgggtgc aggccgacgg tgggctcgtc gaagacgtag gtgacgtcgg tgagcgcgga
    21721 gcccaggtgg cggaccatct tgacgcgctg ggcctcaccg cccgagagcg tgcccgatga
    21781 ccggtcgagc gagaggtagc ccaggccgat ctggacgaac gagtcgaggg tctggccgag
    21841 cacggtgagc agtgtcgtga ccgacgggtc ggtcagaccg cgggcccagg ccgcgaggtc
    21901 gctgatctgc atggcgcagg cgtcggcgat gctgaggccg tcgatcttcg cggaccgggc
    21961 ggtctcgctg agcctggtgc cgtggcactc ggggcagacg gagaacgcca ccgcccgttc
    22021 cacgaaggca cggatgtgcg gctggagcgt ctccttgtcc ttggacagga acgacttgcg
    22081 cacccgcgcg aggaggccct cgtaggtggt gttgacgccc ttcaccttga ccttgaccgg
    22141 gtcccggtgc aggaagtcgt acctctcctg ctcggtgtag tcgcggatcg ccttgtgcgg
    22201 gtcgaggaag cccgactcgg tgaacgactg caccacccag ccgtcgggct tccagccggg
    22261 gaccgtgacc gcgccgtccg cgagcgactt ggagtcgtcg aggagctggg cgggatcgat
    22321 gtccgagacg gtgcccatgc cctcgcagcg caggcacatg ccgccgacga cgctgaagcc
    22381 cttctcgatc ttcttgccgt tcaccacgag gacacccgag gcgtcggccg aggcgacgtt
    22441 gaaggcgaac gccttctgcg acccgatgtg cggcttggcg agccggctga agaggatgcg
    22501 cagcagtgtg cccgcgtcgg tggcggtgcc gaccgtggag cggagactgc tgcccatcgg
    22561 ctgctggtcg acgaggatcg cggtggtcag cccgtcgagc acatcgacct cgggccgcgc
    22621 cagggtgggc atgaagccct ggatgaaggc gctgtacgtc tcgttgatca gccgctgcga
    22681 ctccgcggcg atcgtgtcga acaccaacga gctcttgccc gagccggaga ccccggtgaa
    22741 cacggtcagc cgccgtttgg ggatctccac atgcacgttc ttgaggttgt tctcacgagc
    22801 cccgtgcaca cggatcagat cgtggccgtc ggcggcacac agcccaggag gctgggtgtc
    22861 cgtctccttg ccagcggtca tgttgtccct cccgtttgtc ggacgcggca tgccttcgtc
    22921 aggtgacgtg gtgacgagtt cctgaacgtc ccggttcatg ggactcaagc gtatacctgc
    22981 aaagtcggtt gaggcttttg gaggagctac gcggattcct tgggataaag tctcaaaccg
    23041 tgaagcacct gcgtccgttc gacctggccc gtgagcacgg catctccacc caggcggtcc
    23101 gcaactacga gcgggacggg ttcatcccgc tcgcccagcg caccccgtcc ggctaccgca
    23161 cctacaccga gacccacgcg gcggccctgc gcgcctatct ggcgctcgtc caggcgtacg
    23221 ggtacgccac gggcggagag atcatgcggt cgctcaacac cggcgacctc gacgccgcgc
    23281 tgacggccgt cgaccgcggc cacgcccaac tgctccgcga ccgaagcacg ctggacgcgg
    23341 tgggacgggc ggtggagcac ctcacctccg cccccggcct cgccgagcac acgtccgccg
    23401 gcagcgagcc gctgagcatc ggcgaactcg cgcgccgtct gggggtgacc gcggcgaccc
    23461 tgcggaactg ggaagcggtg ggcatcctga ccccggcgcg cgagccggtc accggccacc
    23521 gctcgttcga cgccacggac gtacgcgacg ccgagctgac ccatctcctg cggcgcgggg
    23581 gctacccgct ggagcacatc cgcacggtgg tccggcagat ccgcacggcc ggcggcaccg
    23641 aggcgctgtc cgccgccctc gacgactggc ggcgacggct cacagcacgc ggcgtatcca
    23701 tgctcggcgc ggcggcccag ctcggcgggt acatggccca ttcgggcgtc ccagccggac
    23761 cgccggccac cacggaaccg gctcccgcgc cggggccccc gccgacggtt tgagacctcg
    23821 cggcccgatg ggtccgaccg ctgcaccggc ggcatcgcag taagcctcaa cgggtctttc
    23881 aatgattcga ttgacagaca tgagcaagga ctttcacgac cttcccgtgg cctcgtgcgc
    23941 tgtgctggcg ctcggcgaac ccacccaccg ggagcccgcc ttcgggtggg tgcgcaacga
    24001 gctgttcgcc cgactggccg aaatcggctt ccgctcgatc gccctggaga ccgaccgcgt
    24061 ggccgcgctg cgcgtcgacg acttcgtcaa gggcggcgac ggggatctcg acgaggtggc
    24121 gcgggagggc ttctcccacg acttcgggaa cctggagacc aaccggtgcc tcgtcgcctg
    24181 gatgcgcgac cacaacgcga gccggccgcc ggaggagcgg ctgagctttc acggcttcga
    24241 cgtccctacg gagacgacga gtgcccccag cccgcggcgc tgtctcgaat tcgcccggga
    24301 ctatctgcgg cttgacctcg acctcgccgg gctgctgggc gcggacgagc agtggagccg
    24361 tgcggaggcg gtgatggacc cggccatgtc ggtcggcgcc acgcccgagg ccgagcggct
    24421 gtggtccctc gccgacgaca tgctcaccct gctccactcc aacgccgccg agcggatcgc
    24481 gcagacctcg cgcgcggagt ggctccgggc cagggcacac ctcaccgccg gcctcggtct
    24541 gctgcgctac caccggcagg cggcccagcg cctggagaac aacgaccggc tgtcccggct
    24601 gttcgccacc cgggacgcgc tcatggcaca gaacctcctc gacatccgca gcatcgaggg
    24661 ccgccggggc gcgtcgctgg tcttcgccca caatgtgcac ctccagcgga ccccaagcac
    24721 ctggagcctg ggagacctgt ccgtcaactg gcccggggcc ggcaccgtcg tggcaccgct
    24781 gctgggcgag cagtacgtct tcatcgtcgg cagcctgggg cgcagcgagg ccgtcgggct
    24841 gggcgatccc gagccgggca cctacgagag ccgcctacag gaccgcgtca ccgattgggc
    24901 catggccccc accggcaagg tcgccgccgc ccggacccgg acggacacca ccccgcagca
    24961 gggctacttc ccgctcgacc gggccacgct ggacaccgcc gacgcggtcc tgcacgtcag
    25021 cgacggcgcc gccgtcagcc gggacctcct gcgcgtaccc gccggtgctg ggagcgggta
    25081 ctgacagaga cgggaaggat tcgccgggct ccccggtcgc cggagattag attcgccgtc
    25141 gatcagggag ccccccgaag gagctgaccg cgcttgaaca cggttccggc actgttcgag
    25201 tcaaccgtcg ccagacgggg cggagaaccc gccctcatcg acggggagag caccctcggt
    25261 tacgcggagc tgaacacccg gatcaaccgg ctcgcccgca ggctcatcgc gcacggtgtc
    25321 ggccccgact cgctcgtcgc ggtcgcgatg ccgaagtcga gcgagctgat cgtggcgatc
    25381 atggcggtgc tcaaggccgg cggcgcctac ctcccgctcg atccgggcta tccggcagaa
    25441 cgcctgcggt tcatgctggc cgacgcgcgg ccggtgctgc tgctgcggtc ctcctcggtg
    25501 gcgcccctcg gcgcgggtcc ggaggaactc gtccttgacg acccggcgtt ccgcgccgcg
    25561 tgcgcggctc tgccggggca cgacgtcgcc cagcatgagc gccgtgccgt actgcgcccc
    25621 gagcacctga tgtacgtcat ctacacctcg gggtcgaccg gaacgcccaa gggtgtcgcc
    25681 gtgccgcaca gcggtgtgcg cgacatggcc gccacccagg cggccgtcct gcgcgcgggc
    25741 ccgggcgacc gcgtgctcca gtgggcgtcc atcagtttcg acgccgcctt ctgggacgtg
    25801 tccctggcgc tgctgtccgg ggcggcactc gtgatggtgt ccgccgacga cctgctgccg
    25861 ggccaaccgc tgtggaacac cttgttcaag tacggcatca cgcacgcggt actgcccccg
    25921 gtggcgctca gcgagaccga cgccgaggac attctgctcg gcgggaccgt catgtccacg
    25981 ggagacagct gtacgccgac gctggtgcgc aagtggtcgc gggcacggcg gatgttcaac
    26041 ggttacggcc cgaccgaggt gaccgtcggg gcgacgatcg gcgggccggt gcgcgacgcc
    26101 ggtgacgtcg ggatcggcat gccgtggatc ggcaacgagg tgcacgtgct cgacgagagc
    26161 ctgcgcccgg tgccgcccgg cacggagggc gagctgtaca tcgcgggcag cggactggcg
    26221 cgcggctatc tcaaccggtt cggggcgacc gcggtgaagt tcgtggccga cccgttcggg
    26281 ccgcccggca gccggatgta ccgcacgggc gaccggggcc gcagggggcc ggacggcgag
    26341 ctgttcttcg cgggccgcgc ggacggccag gtgaagctgc gcggtttccg cgtcgaactc
    26401 ggtgagatcg aaacccggct cgccgcccat ccggcggtgg acgtcgccgt cgccgtggtg
    26461 cggggtgagc tggccgaggc gcatgtcgtc ggctacgtca ccaccacggc gccggtcgag
    26521 ccggatgacc tgcgcgccca tgtcgccgag tcgctgcccg cgcacatggt gcccgcacgg
    26581 gtcacggtgc tggagcggtt ccccacgctg gccaacggca agatcgaccg gggggccctg
    26641 ccgcagccgg acgcgggggc agaggggttc ccggacggcg gccgggcgcc ggacgccgcc
    26701 gaggcggatg gctgcgcggc cgtggtctgc gcgatcgtgc gggacatcct cggggtcccg
    26761 gaggcgaggc tctccgacaa cttcttccag ctcggcgggc actcggttca ggcgaccagg
    26821 ctggccgccc ggatccggga gcggttcgag gtcgcgctgt cgatccggac cgtgctggag
    26881 gcggcgacga tcggcgagct ggccgcggcc gtcgagagcc ggttgtccgg ctgacggccg
    26941 tcagcggaag gcgaccggca ggctgccgta gccgttcagg aagttggagt agatcggtgt
    27001 gggcttgccg cacacctcga tctcgttgac cgactcggtg agcgcgctca gcagtgcgcg
    27061 cagttccgtc cggccgagga acgcgccgac gcagaagtgc gggccgtggc cgaaggagag
    27121 gtgcttgttg ggcgagcggg ccgggtcgaa ccggcgcggc tggtcgaaca cctcctcgtc
    27181 gttgttggcg gaggtgttcc acagcgtcac gatgtcgccc gcgcgcaccc gccggccgcc
    27241 tatctccatg tcccgggtcg cggtgcgggc gaagtgcatg gccggcgtgg cccagcgcag
    27301 tacttcctcg accgccgtgt cgatcgcggc cgacccttcg cgcagcgccc gccactgggc
    27361 ggggtgctcg gcgaacgtct tcaccgcgca gatcgcggac acgcgggagg actcgtcgcc
    27421 gccgagcacg aggctgtagc agttgagagc gacctcctcc agcgtcagcg ggcggtctcc
    27481 cacctccgcc gtcgcgatca tgctgatgac gtcgtcgccg gggtcgccgc ggcggtgccg
    27541 ggcgaggtcc atgaagtaac cgatgatctc gttccgggcc tccagggagt ccagcctgtc
    27601 ggactcggcg tcgtgcgagg agagggccag cttgttccag cgcagcagct tctcgcggtc
    27661 cgcctccgga atggagagca aatcgcagat cgtgttcatc ggaatgtgct cggcgacctc
    27721 cgccgcgaag tcgaactcgc cctgcccggt gacggtcttg atgagccgtg acgtccgttc
    27781 ccatatcttc tgttcgaccg cgccgaggac gcgcggggag aaggcgcgca gcatcaggtt
    27841 gcgcagttcg cggtggcggg gtcggtcggt gaccgcgagc atcttgccgc ctgccgagtc
    27901 accgccgctc agaaggacgt ccagcacggt cccgcgagcg gaactcaggg atcgtacgtc
    27961 ggcgtagcag gacagcacgt cggcgtggcg ggcgacgacc cagaagccgg ggtccccctg
    28021 gtgccagtac acgggccggg acttccgcac gtcgcgccag aactcgtatg cgtcgtgccg
    28081 tacgaaggcg gtcgcgtcgg tcaggtccag ctcggtcggg atggtcatgc cggaagcgtg
    28141 ccaacggcgg cgccgacgcc gggtatttct tgctcaggta tttctccttg aatgagagac
    28201 gaaagattgc tgatcagctg gttcgtttcc gtgtcacgct caggcatatg ggtcgttggc
    28261 cgcgccggac tgtccggcgc ggccggcaga tcacctttga cgaggaggcg gcgtcttgag
    28321 cagtctgacg tatgcggact atctccgaat ggagagtctg ctttcgctcc aggagccgcg
    28381 gaccccacac acggccggcc gtgcggtcgt cctggccgag cagttcttca tcatcaccca
    28441 ccagtcctgc gagctgtggc tgaagcagct cggggctgat ctggacgccg ctgccgaggc
    28501 gctcctgccg ccctgtgaca cgcacgatct ggagctcggg ctcgaattcc tgctgcggtc
    28561 cggcgagttg atacgggtgc tccagcagca gcttctggtg ctggagaaac tgccactgcg
    28621 ttacttcgcc gagttccggt cctatctgga cacggcgagc ggcgcgcagt ccgcgcagtt
    28681 ccggcggctg accacgctgc tgggcaacag ccaccaccag ggcagtctct acgaggcgtt
    28741 cgcggcggcg gtcgagtacc acgggcagac cgtggacgac gtctgccgac gtggcgtgga
    28801 gtccggcgtg ctgcaccgcc tcgcggaagc gctggtggac ctggggaacg ggtactggca
    28861 ctggaaagtg gcacacctgg cactggtgtc caagatggtc ggggagcagg gcggaaccgg
    28921 cgggtcgagc ggtgtcgact tcctcgcccg ccgagtcacc cggcccttcc ccgaacttcg
    28981 ccggctgcgc gggaaggtgc accacccata gccttcggcc gccggccagg gcgtgtccac
    29041 agcgccgagg cagtctgccc ggctttcgcg ggccgcggtc agcgatgtcg gaacgggccg
    29101 cacccccgtc ggttccgcct cgtcctgaac cgcccccggc atcgtgccgg gggcggttcg
    29161 cgggcggggc atgtcgtcct gggcgtcggg gtggacgacg gccggctcct cggggcgggt
    29221 tcgcgggtgc cgcccgcgcc gacggtgatc acgtcggtgc cttcgcccat cgccacggac
    29281 tggggtggca cgatgcggaa cgggccacgt gccgtcccgt gcgatcaccc cgcgtcatga
    29341 gcgtgatcat tgaggctcaa gacccgcttt cgccgcaccg cctagccggc ctcggtctcc
    29401 agcgcataac cgcgccccca ggccgtgcgg atgaccaggt cggtcggtaa gagacggcgg
    29461 cgaagccgca tgatgtggag gtcgagcgaa ttcctcgtcg gcctctgcac gcgttccgcc
    29521 agccgttgag tgagttcatg ccggtacacc acctccccga agtgctcgat gagcagctcc
    29581 atcaattcgg tctggacatt cgagatggtg atcgagtgcg gtccgtagct gagcgttccg
    29641 gcggagtcga gggttggtat ctgccggtcg tcgagccggt tctggagagc tttgacccgg
    29701 gcgtcgagat cctcccggga gatgggcgct cggacccagt cttcgaacgg atcgttgcag
    29761 actggcggac gggcacccgc ctccactacg aggagacggg gtacgccgtc cctcttacat
    29821 cggttccgaa ggtctatttg tgccggccat cggacgaaca tgacatcgct ggttgtgcac
    29881 cccacagcac gcgcctcccc gtcgacgcaa agagatggtc actgtcatcg ccggccgacg
    29941 acgttcttgt gtcggccgag cacgcgtaga gggccggagg ccgtggtggt ctggttcggt
    30001 ctccacggcc tcgacccgca gaggcgccgc gcttcctcag gtcagcattc gcgacggcgc
    30061 ctcaccgcac ggcctcagcc gttcatcgcc tcccggagac tgcgcggccg catgtcggtc
    30121 cagtgctcct ccacgtaggc gacgctctcc gctcttgcgg cggggccgaa gacgctgcgc
    30181 cacccggcgg gcacctcggc gaatgccggc cagagggagt gctggtcctc gtcgttgacc
    30241 agcacgtgga actggccgtt ctcgtcgtcg aacggattgg tgctcacctg tgtcctccag
    30301 aactcgttcc accagttggg gcttcgaaca ggatcactgc gctgcccgca gataccggtt
    30361 gatggcgcgg ctgatctcag ccgcgttccg cggccagtac atctcgttgt gagcgcaggc
    30421 gatgtcgatg cgctgcacac gaccgtcgac gtgctcctgc cagagcacgt ccagttcctc
    30481 gtccagttcc cgcttgtcgt gggtctccgg gtcgagaagt gcgttgaaga agacgacgtc
    30541 accgcggtac cgcggtgagg tgaaccgccg catctgctcc atctgtccga tgaagatcga
    30601 ggaggcggtg gtgaccagcg acgggtactc ctccatcccc gccaggtgtc ccatgtagtt
    30661 ggcgaggtag cggcggacca tggcctcgtc cagcgcttcc aggtcggcga agtggctgga
    30721 gggcgcggcg tccagcagcg ccaggagtgc cacctcgtgt ccgcggcgct ggagttcggc
    30781 cgccatggcg tgcgcgaggg tgccaccgaa ggaccagccc agcaggtggt aggggccgct
    30841 cggctggacc tggagcacct gcccgagata gtcctcgacc atctcctcga tggagccggc
    30901 cggcggggtg gtgccgtcga agccgcgtgc ctggatgccg tacagcggcc aggacggctc
    30961 gacgtggcgg gcgaatccca ggtagggcca gctcaacccg ccacccgggt gcagccacca
    31021 cagcgggggc cggtgcccct cggtgcggat cggcagcagg acggcgaacg ggtcctcgaa
    31081 gtcggcctcg gtgtcggcgg acagctgtgc cgccagtgcg gctacggtcg ggtactggaa
    31141 taccgtgcgg atcgggacgt ccacacccag cttctcgtgg atccgccaga cgaggcgcgt
    31201 cagccgcagg gagtggccgc cacaggcgaa gaagtcgtcg tcgatgccga tccggtccat
    31261 gcccagcacc tcggcgaaga gcgcggcgag ttcctcctcg cgcggggtgc gcggggcccg
    31321 gtgttcgccg ccgaccgggt ccggctcggg aagcgcggca cggtccacct tgccgttctc
    31381 ggtgagcggc agccggtcga ggacgacgat gtcggcgggc atcatgaact ccgggagccg
    31441 gcctgcgagc cgctcgcgca gcagggaagg cagccgggag acgcggcggg agaccgcggg
    31501 cacgttcgcc agccgggccg agctggcgcc ggcgggccgg tagaggccgt cgcagcagac
    31561 ggcgtcgacg tcgggcatga cgatcgcttc gaagcagtca cccgcctgtg ccgaccaggt
    31621 gcagtacacc gcgagcccgc gccgggcgcc ccatgcctcc aggtcggcgg ggtcgagtgt
    31681 gccgcccact tcggcggggg cgccccactc ggcggcctcg ccggccaggc gggtgttggg
    31741 gatacgggtc aggcgcagcc ggccgccctg gcgggccagc gcggtctcca ggtcggccag
    31801 ttcgcggacc tccgctcccc agacctcctc aggcaggtca ccgaggtgca atggcctcgc
    31861 gggcgccttg tgcagcacga cctcgtagcg gtggcgagtc agctcgttgt ggtgggtgcc
    31921 ctgcttgagg cggatgtcgg cggcaacggc gtccggccgg gtctcggccc agcgggtgaa
    31981 gaagcccggg tcgacgacga gttccttctc gccgagcacc gcgcgctcga cggcggcctg
    32041 tacggcggcc gggccgtcgt cgggctgccg gcagcggtgg accgcggcgg cgaacgtgcg
    32101 cagggtgcgg taattgcgga cgtcgccgat cacgacacgt ccgccgggtg cgagccggtc
    32161 catcgcgagg tcgagcaccc gggtgaggta gtcggcgtcc gggaagtact gcacgaccga
    32221 gttgaggatc accgtgtcga agtacccggt gggcaggccc tcggcgtcgt cggcgggctg
    32281 gcagcgcagg gtcaccttgt ccgacagcac cgggtcggcg ccggtccggg cgcgcagccg
    32341 ttcgacgacg ggggccgaga agtcggtgcc ccagtactcc tcggcctccg gtgcgagcgg
    32401 gccgagcagc aggccggagc cgacaccgat ctccagcacc cggcgcgggc gcagggaccg
    32461 tacccgtcgc agcacggcct cgcgccaggc ccgcatctcg gggagcggga tggggcggct
    32521 cgtgtaggag ctgttccagc cggtgaagtc ctcggactcc tcggtgtcga cctccgtccc
    32581 gccgtacatg gtgtcgtaga tctcgcgcca ctcgccgacc tgttcggcgg cgtcgcggcc
    32641 cgtggacacg gagccgtcgg gcaccacgta ggcgaccatg cggcgttcac cgagccggtc
    32701 ctgacgcacg gtgaccaccg cgttcgccac gccgtcctct tcgcgcagga ccgtttccag
    32761 ctcaccaggc tcgacgcgga agccgcgcag cttgatctgc tcgtcgctgc ggctgatgta
    32821 ctgaaggcag ccggcggtgt tccagcgcac caggtcgccg gtgcggtaca tccgcgcccc
    32881 ggactgtccg gacgggtcgg gcacgaaccg ggtggcggtc aggcccggcc ggcccgcgta
    32941 accgcgcgcc acgccgtcgc cgccgatgta cagctcgccc accacgccgg gcggcaccgg
    33001 cagcagccgg tcgtccagga cgaggagccg gctgccgtcc atcgggctgc cgatgggcag
    33061 cgggtcggtg cactccgccg cagaggccac ccggtgccgg gaggcgaacg tggtggtctc
    33121 ggtcgggccg tagccgttga ccacggtgac gccgggacag gcgtcgagca ccgcgcggac
    33181 ggcggtcggc gagaggacgt cgccgcccgc ccacacctcc tggacggcgc cgaagcactc
    33241 ggcgtgctgt tcggccatca cggcgaacag tccggcggtc agccacagcc ccgtcacctc
    33301 ccgctcggtg atcacccggg cgagttccgc ggtgtccggc cggccggcgc gagccaccac
    33361 ggccgtgccg ccgccgagca gcggcaccca catctcgtac gtcgacgcgt cgaaggtgtg
    33421 cggcgagtgg aggaggacgc ggtggtgggc gccggtgccg aagcagccgt cgagcgcgag
    33481 gtcgacgacg ttccggtggg tcacctccac gcccttgggt cggccggtgg aacccgaggt
    33541 gtacatcacg taggcgacag cgtactcgcc gacgccctcc gtctcgggcg gcgagtcggg
    33601 cagcccgtcg agatcctcct cggcgaggtc ctcgtacacg gtgacggccg gggcgaggtc
    33661 cgcgagcagg tagtcgatgc gctcgggcgg gtagttgggg tcgaccggca cgtaggcggc
    33721 gccggtcttg aggacgccga ggacggcggc gaccagcagc ggcgagcgtt ccagcacgag
    33781 cgcgacgcgg ctgtccgggc gggcgccgcg ggcccggaag tggtgggcga ggcggttggc
    33841 ccagcggtcc agttcggcgt aggtccaagc gagcgtgccg tccgcggaga ccagcgcggt
    33901 cgcgtccggg gtcgccgcgg ccgtggcggc gaaccgctcg ggaagggtgc cggcgtcgaa
    33961 ccgggcgtcc cggcctccgc cgccccagcc gctgagcgcg gcgcgctcgt gctcggccag
    34021 gacgccgacg gatccgatgg gcgtctccgg cgcggcgacc acctggcgca ggaagtgcag
    34081 ccagcggtcg agcagcgtgc tgaccgtccc ggcgtcgaac agctcggtgg cgtactccgc
    34141 gaagccctcg atacgggccg gcgcgccgtc ctcgtcctgt tcggtgacgc tgatgaacag
    34201 gtcgaagcgg gaggtgcccg gggagaacgg ctcctcggtc acggtcaggc ccgccaggtg
    34261 gaactccggc cgcgcgttgt tctggagcgc caggcacacc tggaacagcg ggtggtgggc
    34321 gggcgagcgg accgggttga gcttctcgac caggtgctcg aaggggatgt cctggtggtc
    34381 gtaggcggcg aggctgctct cgcggacccg gccgacgagc tcggcgaagg aggggtcgcc
    34441 cgaggtgtcc gcgcgcaaca cccacgtgtt gacgaagaag ccgaccaacc ggttgagcgc
    34501 ctcgtcggtg cgtccggcga tgggcgagcc gatcgacacg tccgtgcccg cgccgagcct
    34561 ggtgagcagc gcggcaaggg ccgcctggag caccatcgac accgtggcac cggtctcccg
    34621 ggccagcctg cgcacgccgt cggtgagctg cgggtcgagt gcgagcggca ccaggtcgcc
    34681 ggcgtacgac gccgcggcgg gccggggccg gtcggcgggc ggcgagacgg tctcgggcag
    34741 gccggccagc tgggtggtcc agtagtccag ctgccgccgg tagaggctgc ccggggtgtc
    34801 ggtgtcgccc agcagttccc gctgccagag ggtgtagtcg gcgtactgca cgggaagcgg
    34861 ttcccactcg ggcgcccggc ctgcgcggcg ggcctcgtac gcggtggtga ggtcctgggc
    34921 cagcgggagg gcggaccagc cgtcggcggc gatgtggtgt gcgccgatca ggaacaccgc
    34981 ctcgcgctcg ccggtccgca gcagccagga gcggatgggg atctcggccg ccaggtcgaa
    35041 cgggcggcgc gccgccgccc gcagggcgcc gggcagctcg gcctcggtga tctcgcgctc
    35101 ctcccacggg acctcgacca cggccggttc caggatgcgc tggtacggct gtccgtccgc
    35161 ctcgccgaag acggtgcgca gcgattcgtg ccgcacgacg acgtcgtgca cggcgcggcg
    35221 cagggccgcc gcgtcgagtt cgccgcgcat gcgcagagcc agcgtgacgt tgtaggtcgc
    35281 cgagggtccc tcgaagcggt ggatgaacca cagccgctgc tgggcgtacg acagcggcag
    35341 ccgttcgggc cgggcctggg gacggagcgg cgggcggacg ttgctcaggg tgttcaggtg
    35401 ggccgccagt tcggcgacgg tgggcgactg gaagacgacc cggatgggga tctccacacc
    35461 gtgctcggca cggatacggc tgaccagccg ggtggccagg agcgagtggc cgccgacggt
    35521 gaagaagttg tcgtccacgc cgacctggtc gagtccgagt accgcggcga acagcgcgca
    35581 cagcgactcc tcctccgggg tggagggagc ccggccgccg ccgaccacgt agtcgggcac
    35641 gggcagggcg cgccggtcgg gcttgccgtt gtcggtcagc ggcacggcgg cgatgggcac
    35701 gatggcggcc gggaccatgt actcgggcaa ggtctcccgc agatggccgc gcagggcggg
    35761 cagcagcgcc gtgacggcgg cggcggccgc ggggtcgttc gccggggtgc gtccgtcggt
    35821 ggccggcagg tacgtgccgg tgagggtggt gccggcggcc gggccgtcgc gcagcacgat
    35881 cacgtcgagc aggtcgaccg cgtcggccga ccaggtcggc accgcgtccc agccgtgccg
    35941 ggcggcccag gcgcggatct cggcggggtc gagcgggggc agttcgggcg ccgcggagtc
    36001 gtcgaggccg agggcgcggg ccgccgcggc ctcctcggtg aggcgggcgt tcgggattcc
    36061 ggtgatccgc accgccggct cggaccggtc acgtaaccgg tcggcgagcc ggccgaggtc
    36121 gccctcccag gtcagggtgg ggacgacgtc gagccgtcgc ggggcgtccg ccggtgccgc
    36181 gcccggcttg tgcagcacga cctcgtagcg gtgccgggtc agctcgttgt ggtggatgcc
    36241 gttcttggcg cggatgtcgg caccggtcgc cccggcccgg tctgcccagc gcaggaacga
    36301 ctcggggtcg accaccagtt ccttctccag caggacggcc tggtcgaccg tggtgcgcag
    36361 tacagccggt gccgcatcgg ggtgcttcgt ccgctggacg cccgtctgga gcgtgcgcag
    36421 ggaggacgcc cgccggatgt cgccgaggac gatccggccg cccggcgcga gcagttccca
    36481 ggcgccgtcc aggacccggg cgaggtagcg ctcgtcgggg aagtactgca cgaccgagtt
    36541 gagcaccacg gtgtcgaatg tgccccgggg cagtccggtg aggtcgtcgg cggcctggcg
    36601 gcgcagccgg acccggtcgg ccaggccggc ccgggtcacc tggtcgctga gccggtcgat
    36661 cacggcctgg gagaagtcgg tggcccagta ctcctccacc cggccggcga tgtgcgcgag
    36721 caggagtccg gtgccgacgc cgagttcgag gacgcgctcg ggcgaccagc acaggacgcg
    36781 ttccacggcg gcatcgcgcc agtcccgcat ctcgtcgagc gggatcggct cgccggtgaa
    36841 ggagctgttc cagccggtga agtcctcacc gaatccgtgt ccgttgtcgt gggagtaggc
    36901 ctggtcgtag acctcctgcc actcccccac ctgttcgtcg gcgtcgccgt cgggccgcag
    36961 ggcgccggtg tccgggacga cgtaggcgac cagccgcagg tcaccgggcc ggtcctcgcg
    37021 ggcggtgacg atggcctggc ggacggccgg gtgccggacc agggtgtgtt cgatctcgcc
    37081 gggctcgacg cggaatccgc gcagcttgac ctggttgtcg gcgcggccga ggaagcagat
    37141 gttgccgtcc gggaagaaac tggcgcggtc gccggtgcgg tacagcctgt cgccctcacg
    37201 cgcgctgaac gggtcgcgga cgaaacgttc cgcggtcagc tcgggccggt tgacgtaccc
    37261 gacgcagagg cagtccccgc cgatgtacag gtcgccctcg acgccgacgg ggcacggctc
    37321 catgttctcg tcgagcacgt agtagcgggc gttgtcgatg ggacggccgt acggaatgct
    37381 gcgccaggcc gggtcgatct cccggacccg gaagtagttg gaccacaccg tcgcctcggt
    37441 ggcaccgccg aggctgacga tctccgcgcc ggtgaacacc cggcggacct cgtcgggcag
    37501 cgacagcggg gtgtagtcgc cggagaggaa caccaggcgc aggtcgtcgg tgccctcgta
    37561 cccgccgtcc tccgtgagca aggaggcgac ctgattgagg gtggtgggca ccgagtccca
    37621 gaaggtgatc ggttccgtga gcaggacgtc caggagcagc tgggggtcgc gctgctggac
    37681 agcgtccgcg atgtagacgc cgccgccgca gccgagcagg ccgaagacgt cgaagacgga
    37741 gaggtcgaag ccgagcgacg tgacgcacag ggcgacgtcg tcggggccga acgcgaaagt
    37801 gcggtagcac cagtcgagca ggttgtgcac cgggcggtgg gtgaccgcga cgcccttcgg
    37861 cttcccggtg ctgccggagg tgaagatgat gtacgccgtg ttgtccgggc ccgcggccgg
    37921 ttccggatcg tggtcggggc cgggcgaccg ggcgtcggtg agctcgacga ggcggacgcc
    37981 gtccggcagg gcccagcgtt cggtgtccgg cgtggacagc acgagggagc acccggcgtc
    38041 ggcgagcatg ccggccacgc ggtcggcggg cagcgccggt tcgagcggca gataggcgcc
    38101 gcccgccttg agcacgccca ggacggcggc gatcatgacc gggccgcggg ggacgccgac
    38161 gccgacgacg gtctccgggc cgacgccgcg ttccttgagg tcccaggcga cgcggttcgc
    38221 ccaccggttc agctcgccgt acgtcatggt gccgccggcc cagcgcaggg cggtggcgtc
    38281 cgggcggcgt gcggcctgct cctcgaagag caggtggacc ggtcccggac agtggaccgg
    38341 gcgggcggtg tcgttccact cgacgaggat cttccggcgt tcggcggcgt cgagagtgcc
    38401 accggaccga ccgggcccgg cctcgcccgc tgcgccgacg ggggtcctcg ggtcggccac
    38461 gacctcctcg acgacggcca cgaaccgtgc cgcgatctcc tccaccgtgg agcggtcgaa
    38521 gaggtcggtg gcgtactcga tctcaccgac gacggagccg gtggactcgt ccggcgccag
    38581 gttgaagaac aggtcgaact tcgcgctgcc ggtgggcagc ggttccatcg tcacggtgag
    38641 acccggcagg tccaagtgcg gtggggtgtt gttctgccac gccagcacga cctggaacag
    38701 ggggtgatgc gcggtcgacc gttccggccg caacagctct acgagccgct cgaacggcac
    38761 gtcctgatga tcataggcgg caagcgcctt cttccgtacc tgttccagca cccactcgaa
    38821 aggctggtcc gccgtcacct gcacgcgcag cgtccaggta ttgacgaaga accccacgag
    38881 ttcattcagt gcctcctccg tacggcccgc gatcggcgag ccgacggtca catccttgcc
    38941 tcctcccagc cgatgcagca acgtcaccaa ggcggcctgg agcacgatcg acgtcgtgac
    39001 gccatgggtt tgcgccaact tttcgacccc ggcgcgcagt tcggcgggca acccgaccgg
    39061 aaccgatccg ccccggaaac tcgccacctc gggacggggc cggtccaggg gcaggggaag
    39121 aggcttggac acaccagcca gttcctcgcg ccaataggcg ctctgcaccg cgacaacgct
    39181 gtccggatcc ttttcgtcgc ccagcatttc gtgctgccac agcgcgtagt ccgagtactg
    39241 cacgggcagt tcggaccagt ccggtgccgt gccggtcacc cgggcccggt aggccgtcga
    39301 cacgtcacgt gccagcgggg ccagcgagcc gccgtcgcca gcgatgtggt ggatcaccag
    39361 gacgaccagg aattcctcgt cgccgctctg gaggacgcag ccgcgcagcg gcacgtccgt
    39421 cgacaggtcg atccagctgc cgctcaccga cgccaccacg ccgggtatcc gctcgggggc
    39481 cacccggccc cagtcctgcc agggcagttc gatctcgtca gagtcgagaa cacgctggta
    39541 cggctggccg tcggtctccg cgaagacggt acgcaggacc tcgtggcgga tcatcacgtc
    39601 acggaaagcc gcccgcagcg cgaccgtgtc gagcgggccg tggcaacgca ggagcagcgg
    39661 gatgttgtag gtggaggaag ggccttcgaa gcggttgatg aaccacattc gccgctgcgc
    39721 gtacgacagg ggggtcatgg tgtttcctac ctttcggtca ttctccgcag cggcattcgt
    39781 gtggaggccg acatctcgtt ccagcggtcg gtcagttcgg cgacggtcgg ggcggtgaac
    39841 agaacgcgca ttgggatttc cacgcccatt tcggcgcgta cccgggccac cagtcgggtg
    39901 gccatcagtg aatggccgcc caggacgaag aagtcgtcgt cgagaccgat ccgctcggcg
    39961 cccaggacct cggcgaacag cgcgcacagc gtctgttccc ggggcgagcg cggagcccgg
    40021 tactcgtccc cgccgaactc cgggcggggc agggcggaac ggtcgagttt gccgttgggc
    40081 gtcagcggca gttccgtgag cgtcacgaac gcggccggga tcatataggc cggcagccgc
    40141 tctccgaccg cctcccgcag gagttccgtg gtgggcggct cggtgccggt ctccgggacc
    40201 acgtacgcca ccagccggcg gtcgcccggc cggtcctcac ggtcgatgac gaccgcccgg
    40261 cggaccgcgg ggtggcgggt cagggtgtgc tcgatctcgg cgggctcgat ccggaagccg
    40321 cgcagtttga tctggtggtc ggagcggccg aggtactcca cctcacccgt gaccgtccag
    40381 cgggcgagat ccccgctgcg gtacatccgc tcgcccggtg gcccgaacgg gcaggccacg
    40441 aaccgctccg cggtcatgcc cggcctgtcg tggtagccgc gggccaggcc ctcgccggcg
    40501 atccagaggt caccggcagc gccgggcggc accgggcgca gtgtgcggtc cagtacgagg
    40561 atccgggtgc cggcgaccgg gccgccgacc gagggaggca tgccgcagtg gccggggagc
    40621 agacgggcgg cggtggcgta gacggtggtc tcggtcgggc cgtagaggtt ggtgacctcg
    40681 gcggcgtgcc ggcacagggt ttcggcgagc gccaggggca gggcctcgcc ggtggagatc
    40741 acccgcagcc cggtcagaca ggccggcgcg tgggtgacca ggctctgcca gagcgcgggg
    40801 gtggcctgca tgacggtgac gccggaccgt tcgacgaggt cgagcagtgc cgtcggctgg
    40861 gtgatgtcgt ccttgccggc cagtaccacc cgcccgccgg cgagcagggg caggaagagt
    40921 tccagcgcgg cgatgtcgaa cgcgacggtg gcgcaggcca gcagccggtc gtccggcgtg
    40981 aaggagaatc gatcctgcat accggtcagc aggatcgcca gcgcaccgtg ccggaccacc
    41041 acgcccttgg gtgtgccagt ggagccggag gtgtagatga cgtaggcggc gtggtcggcg
    41101 ccggccggaa cgcgcgggcc gtgggcaggg tggggggacc ggtcggacag gtccaccccg
    41161 gccagccgtt cctcgtcgag gaccagcacc ggtgcgctgt cctcgaccac ggcccgcacc
    41221 cgggcggccg gatactccgg atccaccggc acatacgtgc cgccggcctt ccacacggcc
    41281 agcagggcca ccaccaggtc ggccgaacgg ggcagcagca ccacgacccg ggactccggg
    41341 cccacaccct gcccggccag ccagtgcgcc agccggccgg cccgttcgtc cagctcccgg
    41401 aaggtcagcc ggtgcccgcg gaactcgacg cagaccgtgt ccggcgtcgc cgccgcccgc
    41461 gccgcgatca gctcggggac ggtccgctcg gggggcggga ccgtggtgtc gttccagccg
    41521 tgcagcacct gttcacgttc ggcgtcggac agcacgtcga gcgcgccgac ggtggtccgc
    41581 ggaccggcgg cgatctgccg cagcacccgc accagccggt cggcgagcgc ctccacggcg
    41641 gtccgctcga atgcgttgcg ccggtactgg aaggagatcc gcaacagcgg gtcggccgcc
    41701 gcgatcacgg tcagcgggta gtgcggcggg gcgtacgggc ggataccgct caccaccggt
    41761 tgcgccgacg cgcccgccgc cgagcggccg gaccggtcga cggggaacga ctcgaacacc
    41821 accagcgtgt cgaacagcgc gttcagcccg gtcgctcgct ggatgtcggc gagccccaga
    41881 tggtgatggt ccaacagcct cgcctgggcg tcctggagcc ggccgagcac ctccgggacc
    41941 gggtcggccg gcgtgcatcg cacccgcacg ggcaccgtgt tgatgaacag gccgatcatg
    42001 gtgtccgcgc ccggcagccc ggagggccgg cccgcgaccg tggcgccgaa cagcacgtcc
    42061 tcgcggccgg tgagctgcgc gagcaccatg gcccaggcgc cctgcaccag ggtgttgggg
    42121 gtgaggcccc actccgcggc ccggcgcgcc agcatggtgg tgtcctcgcc ggtgagcggc
    42181 acgtcgatct gctcgctgcc gctgccggcc ggccgggccc cgggcgtcgt gggcgccagc
    42241 agggtcggct cggccacacc ggcgagttcc tcggcccacg cgcgggcgga gcgtgccgtg
    42301 tcctgccgtg acagccagct caggaagtcc cggtagccgt gcgggcgcgc cggcgcggtg
    42361 tcgacgccgt cggccccgta cagctgcatc agctcgcgct cgacgagcgg caccgaccag
    42421 ccgtcgagca gcacgtggtg ggcggtgagg gccagttcgg cgtgttgggg gccgagcgtg
    42481 acgagggtca ggcgcagcag cggcgggctc tccgggcgga agcgggcgtc ccgctcctcg
    42541 gcgaggatct cctccagccg ggtggcggcg tcggcctcgc cggtgaggtc gaggtgccgc
    42601 cagggcagcg ggacgtcgtc cacgacgacc tgcacgggct caccggtggc gctcggccgg
    42661 aacgcgaccc gcaggttcgg gtgccggtcg agcagggcct ggcccgcggc ccgcaggcgc
    42721 gccgggtcca ccgcgccttc gagccggaac acgaactgcg tctggtacgc ctcggatgcg
    42781 ctctgcgcga gcatcgtgtg atacagcagc ccgtcctgca acggcgtgag cggccatacg
    42841 tcgctgacgc gcccgaagcg ccgttgccag ccgtccagtt cctcctggcc gacggtgacc
    42901 agcgggacgt cggacggggt cagtccccgc ccgccggacg cgaccaggct ccgcaggccg
    42961 cgcagtgcgg cgcaccaggt gccggacagg gcgcggacct cgtcggtggt cagcactccg
    43021 gtggcgaagg tgaacagggc ggtgaggcgc gcgtcgtcgc cggtgccggt caccagggcg
    43081 ttcagttcga gcgcgctggg cgccggcatg tccgcggcgg gtgcggcgac caactcggcg
    43141 cattcgggcg ccggggtcca tccggagccg cgggtggggt cctcgccggg cgccggctcc
    43201 gggcgttcga aggtgaaacg gcccaggaag ttgaatccga tgtcgtccgc cggatacggg
    43261 ctcagcagcg ccgcggtgtc gtcgttgagg tagcgcagca gggtgtagcc gatgccctgg
    43321 tcgggtaggg cccgccgctg ctccttcacc cgcttgaggg cgtcaccggc ggcggctcct
    43381 ccggtgatcg cggcgtcgac gtcgatcccc gagacgtcga tgcgtacggg ggtgaccgtg
    43441 gtaaaccagc cggccgtgcg ggacaggtcc gcgcccggca ccagctcctc ctgccggccg
    43501 tgcccttcca gccgtacgac cgtcgtgccg tcggtgagac cccgccgttc ccgggccagc
    43561 gcgaggacga gggcggtgag caggacgtcg tccgcgccgc tgcggtaggc cgcggggacg
    43621 gaggtcagta tcgcgtccgt gaggtcggcc gggagctcca cccggacggt gtccgtggtg
    43681 gaggtgaggt ctcgcccggg gtcaagcggc cgggagccca cgggtgcgac gggtgcctcg
    43741 agcaggtcgc gccacaacgg cacctccgcc acccgtccgg ggcgggccgc ctcgtcggcc
    43801 agggcgtgca gccatcggcg cagggaggtg cccacccgcg gcaacgcggg gggccggcct
    43861 tcctggacct ggcgccaggc cgcggccagg tcgggcagca gcacgcgcca ggacatgccg
    43921 tccacgacca ggtggtgggc cacgaccagc agccgtccgg gcccgcccgc ggcccccggg
    43981 aaccagacca gccggagcat ccgcccggcc cgggcgtcga tgtgccgtac ggcctcggcg
    44041 gcctttgcgc gcagcagggt ctgccactcc tcgccgcccc agtccccggg gcagtcgacc
    44101 cggtcgacga atccgccggc gtccggagtg ccgggtggct gcaccagcag gccgtcgtcc
    44161 gtcagccgtg agcgcaggac gtcgtgccgg tcgaggacgg cgcgcacggc cgcggtgagg
    44221 ccggggaggt cgacggctgc gggcagttcc agtaccagcc actgggcgag gcggtccagg
    44281 ccggggcctc gctcggcgta cagccgggcc atggggggca gcggcagcag accgacgccc
    44341 ccgccctcga gctcggcgag ggctaccggt gcggtgtcgc gggtcgcggc ctgcgcgagc
    44401 gcggcgacgg tgcggcactc gaacacggtg cgcggggtga gcgcgagacc gccggcgcgg
    44461 gctcggccca ccacctggat cgcccggatg ctgtcgccgc ccagagtgaa gaagtcgtcg
    44521 tcgaccccga tgtggctcag gccgagcacc tcggcgaacg cggcggccag gaggctctcg
    44581 tcaccggtcc ggggcggccg gtgggcacgg ccggtgacct ccggctcggg cagcccggcc
    44641 cggtccagct tgccgttcgc ggtcaacggc atccggtcca gcgcgacgaa ggcggcgggc
    44701 accaggtggg cgggcagccg ggccgcgacg aagccccgca gctcggcgat gtccaggccg
    44761 gcgtgcaggt cccattcggt gccggttccg ccgttgccgc cggaggtggc cgggacgacg
    44821 taggcgacga gctgcgcggc tccgtccgcg gctcggccgg gccgggcgac gacggccgcc
    44881 ctgagcactc ccgggtggtc ggtcagcgtg tcctctatct cctgcggctc gacccggaag
    44941 ccgcggatct tcacctggtg gtcggcgcgg ccggcgaact ccagttcgcc gtcggtgttc
    45001 cagcgcgcca ggtcgccggt ccggtacatg cgccgcccgg gttccccgaa cgggcaggcc
    45061 acgaagcgct cggcggtcag ggcccgacgg tcgtggtagc cccgggcgag tccggcgccc
    45121 gcgatgtaga ggtcgccgaa gacgccgggc ggcagcggtc gcagccggct gtcgaggacg
    45181 tagagcgcgg tgttccagat cggggtgccg atcggtatcg tccgcgcccc gggccggtac
    45241 tgccacgcgg tgacgtcgac ggctgcctcg gtcggcccgt acaggttgtg cagcggcacg
    45301 ccgaaggtcc ggtggaaccg cgcggccagc tcggccggca gcgcctctcc gctgcacacg
    45361 acgcggcgca gaccggtgca cgcggcagcc gtctcctcgg tgacgaactc ggccagcatc
    45421 gacgggacga agtgcgcggt cgtgacgccg gcccgccgga tcacctcggc cagatagtcc
    45481 gggtcgcgat gcccgtccgg ccgggcgacc accagggtgg cgccggtgat cagcggccag
    45541 aagaactccc agacggacac gtcgaacgag gcggacgtct tctgcaggac ccggtcggaa
    45601 ccgtcgagcc ggaagcgatc ctgcatccag agcagccggt tgacgatcgc cgcgtgcgtg
    45661 acgacggcgc ccttgggccg tccggtcgat cccgacgtgt agatcatgta tgcggggtgg
    45721 tcgacccggt gcggggcgga cctgacgggc tcttcggtga gcggggcgtc gtcgaccatg
    45781 accacgggga cgtccgtccg gggcagccgg tccgcggtgt ccttgaccgt cagcagcagc
    45841 gcgggcccgg cgtcggcgag catgaactcg acccgcgcgg ccgggtagtc agggtcgacg
    45901 gggacgtagg cggcgcccgc cctgagcacc gcgaccaggg cgacgaccag ttccagggag
    45961 cggggcacgg cgaccgcgac gaaccgctcg ggcccggcgc cgcgctcggt cagcaggcgg
    46021 gccagccggc cagaccgctc ggccagttcc cggtaggtca cccgggtgtc ctcgaaggtc
    46081 accgcgacgg cgtccggggt ggcgcgggcc tgtcggtcca gcagttcggt cagggtcgtc
    46141 ggcggtgggg tcaccgtggg tccggcgtac tcggtgagca gcgcgcggcg ttcggcgggg
    46201 tgcagcgcgg agacggtccc gaccggggcg tgcgggtcgg cgagggccct gcgcaggaac
    46261 gtcacgaacc gctcggcgag cccggcgatg tcctggtcgt cgtactccgc gcgcggcgcg
    46321 tcgaagcgga cgtacaggtc gctgtcggcc cttccgtcgg tgtagacgca gaccatcacc
    46381 tcgtcgatca cgccgaaggt gccaccggcg aagtgggctg tggcgcccgc caggtcgagt
    46441 gcttcgacgg aggggagcac gttgacgacg gcgccgaacg ggctgcgcgc gtcgccggcg
    46501 tggccggtgg cccgtttgat cagggatatg tcgtgccggg cgtggcgcag gacacggcgc
    46561 cgctcccggc cgagcgcctc agccagttcc acgaagtcgg ccgcggggtc cacccgcgag
    46621 cgcagcggca cccggttgga gaggaggccg agcgagcggc gcagtgcgcc gacgcggtga
    46681 ttgacggtga tggtcagcag ctgctcggac agaccgcaca tgtgccccag gaacgcggtg
    46741 gcggccgagg cgatcaggtc gggcaccgag gtacccgccg cggcggaggc gtgttcccag
    46801 gcggcgagtt cgacggccgg gaccgtcgcg gtgcgggtgg ccatcccctg cggtgcggtg
    46861 aggccgtccc agtagccggg cccgccggtg ggggcgtcgg tgcccggacg gacaccggcg
    46921 ggcagacggg cggcgggcag gtcttcggcg aggtagtcgc gccagaaccg ctcggcgtcg
    46981 gcgaaccgct gcgactcccg gtagacggcg tccttcgccg cggcgtcccc cggcgggttc
    47041 ggggcgccct ccggcaacgc ggagccggcg cgcagcgcgc ggtagatctc ggcgatccgc
    47101 cgggacagca gggtgagaac gccgaacgcg tcggtgagga tgtggtggaa gacgagcacg
    47161 agcaggtggc ggccggggcc cagccggatc gagccgatcc gcagcagcgc gtcctcggtc
    47221 aggtcgaagg gccggcgcac gagatcggcg acgacggcgc gggccgcgtc ggcggggtcg
    47281 gcggcgtcgc cgacatcgag gcggaacggc tcccacgccc cgaggtcccg ggcgaccggc
    47341 cgcagcccgt ggtcgtcgcg gcggaagttc accttcagcg cgtcggcttc cgccaccgcc
    47401 gcccccaggg ccgcggcgag cagggcggtg tccaggtcac cgtcgatgtc ccagagagtc
    47461 gccacgttgt tcggtacgtc cggagtgaat tcctgcgcga gccacatggc ttcctgcgcg
    47521 gatgtgacgc cggtacaacc catccagatg cccccagcaa aagtggtttc ccggtcaatg
    47581 gcctcgccgt gccgatactt gtcgcggccc atgcgctcga acaactggca tgaaagatgt
    47641 tcgccagaga tcgaaaagga ataggccaac acccgaaaca actccgccaa accgccccgg
    47701 ccaacgtccg tccggcccgc ttcaaactgc cctcggacat ctttcggtca cgggtccgcg
    47761 cgttccacgc gttccacgcg ttccaacggc cgtagtccgc ctgctagcgc ggcccctccg
    47821 ccgctgcggc cgggctttcg ttgtcgtgcg cgctggtccg gaccacctcg gcgacggtca
    47881 gctcgtaggc ggagtaccag tgtttcctgc ccagtcgctg cgccacctgg tgctcggggt
    47941 cgcagcgcca cttgtccagc gtctccccgt cccgccacat catgacggcg agacgttcgc
    48001 cgtcctcccc ggtgtagtgc ttgacctcca ccgggtcgga cccggcaatg gcgcggaccc
    48061 gctcctgcat ccgctcctcg gcggcgtagt agtcctcgcc ggcctgctcg gacaggcgcg
    48121 acttgaacag gatcacgaac atacggagtc ctccggggtg gcggtggtcg ggttggggga
    48181 agggatgcag gcgcgcagtc ggtcgtcggg cgccgagacc agctcggtgc cgtaccgggc
    48241 caacagatcc gccacgagcc ggtccagacg ctggtcgtca cgcagtacgg aggcgtagct
    48301 ctcctcggtg aaggcgcacc gctcgtacag cggaacgaac cggtcgggga acagcaccgt
    48361 cagccgcccg cgcagcacct ccgcagcggt ctcctcgcgc ggtgggccgg ccatcgtgaa
    48421 gtagtgccgg taggagagcc gggagatcgc gtcggcgtcc tcggtccgcg acttctcgta
    48481 ggctgccagg cccgccgccc agtccgcgga ggcgtcgagg cagtcgacga ggacccgggc
    48541 gtcctcgaaa ccgcagttca tgccgtgccc catgaagggc gccatcgcat gacaggaatc
    48601 accgagcagc gcgaaggtgt ctcgccagac ccatcggtcg cagcggacgg ccgtgagggt
    48661 cgagacggcc ttggtggcga gctgttccgc gatgtcgggg atgatcccgg tcagctcggg
    48721 gaagtgggcg gcgaacgtct cgtacaggtc ctggccgccg cgggccgccg cgtaggacgg
    48781 ggcggggccg tcgaggcgca tgaacaagga gcccgagagc ttccccgacg gcagggggtg
    48841 cgcggcgaac atcgccttcc cggagggcca gtagtgcgtg atggtcgggt ccagccggcc
    48901 ggccggtacg tcgatctcct ggtaggccag gtccagcgtg cgcacctcgg cccgggtgcc
    48961 gcgcgcctcc agggcggccc gggcggcgga gtgcgcgccg tcgcagccga ggacccggcg
    49021 gcacgtcagc cggtgcgagc cgtgccggtc ctccaccacc accgcgggtt cgtccaggtc
    49081 caccgagccc acgcgctgcc cgaagcggag gcgcacaccg ggggtcgcct cggctgcgtc
    49141 cagcaggatg tggtgcagcc gccggcgctc caccgcccag atgggttgtc cgtcccggct
    49201 gtagggggtc atgcgcgtcc ggccgtcggg caggtgcccg cagcgtccgt gcagggggac
    49261 gcatatgcgg cgcacggcgt ccgcgacgcc caggtccgac agggcgcgcc agccgcgcgc
    49321 ggacagcatc acgaccagtg accggcgttg tccaccggag ttccgcctgg ggtccgcccg
    49381 tttctccagc agggtgaccg gtccgaagcg gggcgccagg tagagagccg tgaccacgcc
    49441 caccagaccg gcccccacga tgacggtctc cgggttcccg tccgtgcggt ccgtgccgtt
    49501 cccgttcata ccgtccttgc ccctcgtccg ttgctccgcc ggcggttgtc gggtcgtgtc
    49561 cgcgtccgca cctcgctatg gccgccgcag ttccgtcagg accgcggtgc cggcctcttt
    49621 cgtactcagg gacccgccga gatcgggggt gacgcggccc gctgcgacgg ccgcggcgac
    49681 cgcccggcgg accgcgtccg cctcctcggt ccggcccagg tgctcgacca gcagggccac
    49741 ggagaggatc gcgccgaacg ggttggcggt gcgggtaccc gcgatgtccg gggcgctgcc
    49801 gtgcacgggc tcgaagagcc cttgtccggt cacggggttg aggttcgccg acgccgccac
    49861 gccgaggccg ccggccagcg cggccgtgag gtcgctcagg atgtcgccgt aggagttgtt
    49921 ggtgacgacg acgtcgaagg cggtcgggtc ggtggccagt cgcagggcgg cggtgtccac
    49981 gtagaggtgg gacgtctcga cgtgcgggtg ccgtgcgacc gcctcgctcc agcaccgctg
    50041 ccacagctgt ccgccgttgc ggacggcgtt ggccttgtcg acgaggcaca ccgacctgcg
    50101 cgccacggag aacgcgaact ccagcacccg tgagacgcct tggtgggtac tgaggtccac
    50161 gtcgatggcg atctcctggg gggtcccggt gcgcgtaccg ccgccgatgc cgctgtagag
    50221 cccctcggtg ttctccctga cgatcacgca gtcgatcgcc cggcgggccg ggtcgcgcag
    50281 cggactgagc ctgtcgtgca ggagcctggc gggccggtag ttgacgtaga ggtcgagttc
    50341 gaggcgcagg gtggtgagga ccgtacgcac gtacgcggtg tcgctgagcc gggggtcccc
    50401 gaccgcgccg aggagcgccg cctggctgga cctgatccgg tcgaggtcgg ctccggtcag
    50461 cgcggttccg gtgcgcaggt aggtctcggc gttgacgtgg tccaggacgt ccgtacgcgt
    50521 cccgaggcgg agggcgtcga ggacgtccag cgccggctcg atcacctcgg gaccgatgcc
    50581 gtcaccgggg atcacggcga tggtggtcaa ggccgcctca cttcgggccc tggctcagca
    50641 cgtccgcgac gagttccgcg acgtcggtcg tcacgtggaa gtgcccgccc ggccgcacgg
    50701 tccccgaaaa gccgccggag gtgacgctcg cccaccccgc cagctggtcc tgctccacca
    50761 gcgggtcgcc cgcgccgtgg tagctgcgca cgggacagga cagcggacgg gtgccggggc
    50821 ggggccggta ggtcgcgtgg gcccgcaggt ccgagcggat gacgggcagg aggaggtcgc
    50881 gcagctcggc gttctcggcg accgcgggct cgatgccgcc cagcgcgcac agggtcgacc
    50941 agaactcgtc gtcgggcgcc aggtggacac ccctgttggt catggatccg ggcggcagtg
    51001 cggcggacac gcagagcgcc cggggttcct caccggcgtc ccgcagcagc agggcggtct
    51061 cgtaggcgac cagcgccccg agactgtgcc cgaacagcac gtggtcgccc ggcggcaacc
    51121 gcagcagctc cgccgccacg cagccggcca tcgcggccac gtcgtccacg ggcggctctc
    51181 cgaagcggtc gccgcggcct gggtactgga cggccatcag cgacacaccg ggcggcaccg
    51241 cggcggacca ctcgccgaag gcgactcccg atccccccga gtgcgggaag cacaccaccc
    51301 ggacgccggc agggtcaccg gcgatcatcg accgcaccca gccgcgttcc cgtatccggc
    51361 tcatccactc cgcctttctg gccggccgtc gttccgtccg caccatgttt tccactcgcc
    51421 gccgattcgc ggggccctcg acagatgtcg gcaagagatc ggggcgcggt ggaacgcggc
    51481 gccgacgatg ccaagggaca caaggaccgc gggcacgccg ccgcatggca ccgggctcac
    51541 ctcgcacgcg gacgcagcgc accaccacac cggacaccgc ccgccaccgt gagaaggcac
    51601 gcgccctcca ccccgcgtcg ccgccgtccc gcggcccgga cggacggagc gcacccgcgg
    51661 ctccacccgg accttcgcgc cccctcgatc cacgcttcga ccgacccgcc gaaagggaac
    51721 gcgatcatgc ttgacggttt tgtgcactgg cccgaacagc tcgcggcgga cctgcgccgc
    51781 acaggggtct ggctcggccg gccgatcggt gacttgttgc acgagtcgtg cgaacggaac
    51841 gccgatcgcg tggccgtggt gtgcggcgaa cgccggatga cctacgcgga gctgtcccgg
    51901 cgggcggacc ggttggcggg cggcctgatc ggactgggca tcaggcccct ggatcgggtg
    51961 gtggtgcacc tccccaacat cccggagttc gtcgtcctgg tcttcgcgct gctgcgggcc
    52021 ggagcgatcc cggtgctggc gctgcccggt caccgcaggg ccgagatcgc gcatctgtgc
    52081 gctcactccg gggctgttgc ctatgtggtg aaggacgagt tcggcgggtt cgacttccgt
    52141 acgatcgccc gggagatccc gtcggtcccg cacgtgatcg tcagcggcga cgcccaggag
    52201 ttcgtttcgc tggagtcgct ggagtcgctg gacgcccagg acgtcgcgct gcccagggtg
    52261 gacgcgtccg accccgcgct gttcctgctc tccgggggca ccaccggact gccgaagctg
    52321 attccccgga cccacgacga ctacgagtac gtcatgcggg ccagcgcgga ggcgatgcgg
    52381 gtgggtccgg aggtggtgta cctcgccgtc aacccggtcg cgcaccaggc ggccctcgcc
    52441 tgtccgggcg tgttcggcag tctcctgatg ggagggaagg cggtactcac gtcgagcgtg
    52501 cggcccgacg acgtcttctc gctgatccgc cgcgaggcgg tcaccgtgac cacggtcgtg
    52561 ccctcggtgc tgcggctgtg ggccgattcc ggacgaccgc ccggcgaact gtcccgcctg
    52621 ctgatccagg tgggcagtgc cccgctcgac ccggccctgg cgcgccgcgc ggcccaggag
    52681 ctgggctgcc ggatccagcg atggtacggc atcagcgagg ggctgctgac ccacacccgg
    52741 ctcgacgacc cggaggaggt ggccgtgaac acggacggcc gcccgatgtc accgggcgac
    52801 gaggtccgga tcgtcgacga gtccgggaac ccggtgcccg acggggaggc cggcgagatg
    52861 caggtgcgcg gtccgtacac gatccgcggg tactaccggg ctcccgagga gaacgcccgg
    52921 tcgttcacac cggacggttt cttccgcacc ggcgacctcg tccggcgcag gccggacggc
    52981 aacatcatga tcgtcggcag gatcaaggac gtcatcaacc gggccggcga gaaggtctcc
    53041 gcggaggagg tggagcggca actgcgcacc caccccgccg tgcaggacgc ggccgtgatc
    53101 ggcgtggcgg acaccgtgct cggcgagcgg acgtacgcct tcgtcgtcct caacgaggcg
    53161 gacgtccgcc cgtccgccat gaaggagttc ctcagaggcc gcggcctggc cacctacaag
    53221 atccccgacc ggctgattcc gatgccgcag cttccgcgca caccgatggg gaaggtcgac
    53281 aagaaggcac tgcgcgcacg gatcgccgcg tcacaacgct gacggtgccg gggtgcggga
    53341 cggattccgc gtccgctccg cgcctgcctc ggtggacttc gaagaacagg tcgagcatcc
    53401 ccggcccgcc acgcctcggc ggttcaggac aaccagcagg tcagtcgtcc ttcttcaccg
    53461 gctccaggat cgccacgcac tccacgtgcg acgtcatcgg gaaggtgtgc agtttgaccc
    53521 cttccaggaa acatgcaggt cagaggcggt ttcgaggcgg aacccgaacc cctcggagag
    53581 cctggtgcgt catacgtgcg tcagacgcgc acggatcctg aacgattccc gccgcacccg
    53641 cgccaacggc accctctacc agcacaagga cagccgctgg gaagccgccg gatacgtctt
    53701 cgccccgccg gccgccgtgg ccggaaagga ctcggtgccc agggccttcc ccagcgggga
    53761 gaccacggcg acaacatgaa cctcgccgtg cgtgtccacg cccaggacga cctcgcccgg
    53821 aacgggagaa tccgtgctgg aggaggtgct gcgctgtctg atcgtcttgg tggttcgcct
    53881 cccgcgtggt gacgtctggg tggatgggca ccgggctgct cgggcggtct gaaccgtgat
    53941 ggcgcctgat cgtcggcaag gcccctgact tgttgaatcg agcccagacg cgcggtctgc
    54001 agccgtagcg tccagggtgc cggtcggcac gggtccgtat gtcccttgcc gccgcctggc
    54061 tggctcttcc atagcgtgcc gccgccggcc ggcacccacg cggtgtggct cgacagaagc
    54121 atgaacgtgt gtgactgcca cttcaagtca gggtgcccac cgcatacttc gtctcttcga
    54181 gcacagaccg ggatgcgcgt gatcaccatt ggga
//
