LOCUS       NZ_BMUQ01000028        42370 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence28, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000028
VERSION     NZ_BMUQ01000028.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 130208)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4493
            Orig. end                         :: 46863
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000028.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..42370
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     cand_cluster    1..42370
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..42370
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:22370](+)"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..22370
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     gene            789..1676
                     /locus_tag="IE289_RS42980"
                     /old_locus_tag="GCM10010317_088310"
     CDS             789..1676
                     /NRPS_PKS="Domain: ACPS (144-210). E-value: 4.1e-08. Score:
                     25.0. Matches aSDomain:
                     nrpspksdomains_IE289_RS42980_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521819.1"
                     /locus_tag="IE289_RS42980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088310"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_229889484.1"
                     /transl_table=11
                     /translation="MTTRPAPPTTPALIPAPEPGPAPASGAGGGEPVKLWLCPNDGLPP
                     EVAGLLATHWLDAQEQKTASRFLFERDRRQYLLAHTLVRRALALEAGLAEAELVIWRSA
                     RGRPFLRPAAAGGPRGGSQLDFNLSHAGGYSLLGIVRRHRIGVDVERLEDRDERAITTI
                     VRTFAAPEREWVARAADGPARDRRALRVWTLKEAYSKARGLGLGLPFDAFAFTLDDERG
                     VRAFTPPADDTARPWRFVELEPVPDVLVAVAVPADEAQDPVLHLGYGFPWSRAALRSFP
                     LPRPVGGHPSALPA"
     aSDomain        1221..1418
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS42980_ACPS.1"
                     /evalue="4.10E-08"
                     /label="IE289_RS42980_ACPS.1"
                     /locus_tag="IE289_RS42980"
                     /protein_end="210"
                     /protein_start="144"
                     /score="25.0"
                     /tool="antismash"
                     /translation="IGVDVERLEDRDERAITTIVRTFAAPEREWVARAADGPARDRRAL
                     RVWTLKEAYSKARGLGLGLPF"
     gene            2031..3278
                     /locus_tag="IE289_RS42985"
                     /old_locus_tag="GCM10010317_088320"
     CDS             2031..3278
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029184.1"
                     /locus_tag="IE289_RS42985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088320"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_190173716.1"
                     /transl_table=11
                     /translation="MQLRYAFRLDPEPGQRVALARAFGCARVVYNDAVAARERARREGA
                     AFPSAGALSKTLITEAKQSPERQWLSEVSAVILQQALRDMERAYTNFFSSLKGSRPGAR
                     VGAPRFKPKRDARQAIRFTANARWKITEAGRLLLPKIGEVKVRWSRRLPSVPSSVTVIR
                     DAAGRFFASFVVATDPGADLARMPEADNLPSVGIDLGLTHFAVLSDGRVIDSPRFLRRA
                     EKKLKKVQRELSRKQKRSNNREKARLKVARAHAQVADARREFHHQLSTRLIRENQAVAV
                     EDLAVKALARTRLGKSVHDAGWAQFLAMLEYKAQRYARVFVKAGRFEPTSQVCSVCGVK
                     DGPKPLHVRTWTCTHCGTVHDRDHNAAKNVKQAAGLAVTACRAQVRPELVPAQREEAGS
                     HGIHTGTRAAQRHSTR"
     gene            3250..3513
                     /locus_tag="IE289_RS42990"
                     /old_locus_tag="GCM10010317_088330"
     CDS             3250..3513
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037627.5"
                     /locus_tag="IE289_RS42990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088330"
                     /product="hypothetical protein"
                     /protein_id="WP_190173717.1"
                     /transl_table=11
                     /translation="MPRSGTAPGEEGQNLPASAGRASQHHPLVGDLTLGFEAFTPIGDP
                     DQTLGLYTVEPGSPSENALCMLASWTADNTHIQPEKAAGHEH"
     gene            3800..5434
                     /locus_tag="IE289_RS42995"
                     /old_locus_tag="GCM10010317_088340"
     CDS             3800..5434
                     /NRPS_PKS="Domain: AMP-binding (15-428). E-value: 4.2e-48.
                     Score: 155.8. Matches aSDomain:
                     nrpspksdomains_IE289_RS42995_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007269018.1"
                     /locus_tag="IE289_RS42995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088340"
                     /product="fatty acid--CoA ligase family protein"
                     /protein_id="WP_190173718.1"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-52, bitscore:
                     171.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPILRYLESPLDDLLRRAAARDANAPALTVAGTGAGVTFAALDRE
                     ADRIAHYVRRAAGRAGAVVAAATTLDAVFPAVYYGTVRSGHPLALLDPLMGPAALYEVC
                     SAAGAEIAFVPAALAGLLAGLGDRLPLLHTVVLTDTPADAATDRPAGGAAGAGGGVPLA
                     RALASVPAGVPARTPAPGVDAVACLQFAPDGAGRLNGVRLTHRNLLAGAAQTALAHRLG
                     PSSVVLNHLPQYHAVHLNSAVHAGARQVLCPGPDPFGALEAAARAGATHFYAPPARLHR
                     LAGDTRLGGAGARTGARRLSALHVSGGALEPDRARRLRDALRVPVLQGYGLTEVCTLSH
                     HQPPGSRPGLGAVGVPLPGTECRVVLPGGTLPAPVWSTGEVQIRGPQLSPTAPAGPAGA
                     VPDADGWLSTGDTGYLDADGGLHLVDASGAVFACDDALVAPAVVERVIGQDPRVADCIV
                     ADWPDPARGALVWAGVVLRERPPGDDRGLLDVLDSVAEQANARLGPGEQIRRLEALDAV
                     PRRPGGRPARRELRRRLHALAAVEAAA"
     aSDomain        3845..5083
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS42995_AMP-binding.1"
                     /evalue="4.20E-48"
                     /label="IE289_RS42995_AMP-binding.1"
                     /locus_tag="IE289_RS42995"
                     /protein_end="428"
                     /protein_start="15"
                     /score="155.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RRAAARDANAPALTVAGTGAGVTFAALDREADRIAHYVRRAAGRA
                     GAVVAAATTLDAVFPAVYYGTVRSGHPLALLDPLMGPAALYEVCSAAGAEIAFVPAALA
                     GLLAGLGDRLPLLHTVVLTDTPADAATDRPAGGAAGAGGGVPLARALASVPAGVPARTP
                     APGVDAVACLQFAPDGAGRLNGVRLTHRNLLAGAAQTALAHRLGPSSVVLNHLPQYHAV
                     HLNSAVHAGARQVLCPGPDPFGALEAAARAGATHFYAPPARLHRLAGDTRLGGAGARTG
                     ARRLSALHVSGGALEPDRARRLRDALRVPVLQGYGLTEVCTLSHHQPPGSRPGLGAVGV
                     PLPGTECRVVLPGGTLPAPVWSTGEVQIRGPQLSPTAPAGPAGAVPDADGWLSTGDTGY
                     LDADGGLHLVDASG"
     gene            5644..6435
                     /locus_tag="IE289_RS43000"
                     /old_locus_tag="GCM10010317_088350"
     CDS             5644..6435
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521637.1"
                     /locus_tag="IE289_RS43000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088350"
                     /product="response regulator transcription factor"
                     /protein_id="WP_190173719.1"
                     /transl_table=11
                     /translation="MDERHATLRVLPAPAPGPDPGPGEAAGPVPAPRPGAPAAVRVHVI
                     GEDPLARRGITALLEGHPGIRVTGESEPGPPLLRALAARPPHVLVAHGALGGGQLAAPA
                     FGGGDLPLLTLGGPGHTDAAGRAAGGHLPATATAGQLASAVVLAAAGYTLVHGPTPPPP
                     GRRPAAGPPAPISPVSPDRLTDRECQVLDLLARGLSNGEIARALTLSEHTVKTHVQNLL
                     HKLRLRNRVHAAIYAFESGLRAPAASLRPAAVAADAPSGSG"
     gene            6915..7280
                     /locus_tag="IE289_RS43005"
                     /old_locus_tag="GCM10010317_088360"
     CDS             6915..7280
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572116.1"
                     /locus_tag="IE289_RS43005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088360"
                     /product="hypothetical protein"
                     /protein_id="WP_190173720.1"
                     /transl_table=11
                     /translation="MASQSSPVSLPSAAEVLRERYAGRLPASLDELSGPAQGRVELPLH
                     VAWSGLRAYDLDRPRQRMSLYRTVLAEGQRDDLITLLDRDLLVAQWPVLRTLVSRHIRL
                     VWEDAFPALARRTPTAA"
     gene            7277..7942
                     /locus_tag="IE289_RS43010"
                     /old_locus_tag="GCM10010317_088370"
     CDS             7277..7942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009998359.1"
                     /locus_tag="IE289_RS43010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088370"
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="WP_190173721.1"
                     /transl_table=11
                     /translation="MNLSELHRRLLADVLAIGTPYPLIITGGYAVQAHGLVDRLSQDLD
                     VATENPAPLTDIVHAVEHGLVQRGWAVTVVSVDPLSARLVAAVPATGEDCEVDILKENL
                     WAPPVETEYGLVLALPDVIGTKVRALADRGAVRDLIDVHAAAEHHTTNDLERLGERHGR
                     DEFRLQDLHDRLAGAEWYDDEEFAAYGLTEDETSRLRAWAQHWASDLNQRLGADDHEV"
     misc_feature    complement(8752..8767)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.87"
                     /tool="antismash"
     misc_feature    complement(8763..8775)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            8888..10114
                     /locus_tag="IE289_RS43015"
                     /old_locus_tag="GCM10010317_088390"
     CDS             8888..10114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568320.1"
                     /locus_tag="IE289_RS43015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088390"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_099918212.1"
                     /transl_table=11
                     /translation="MLRQPAFGHRLKKLRTAQGLSQTALAGEGMSTGYLSRLESGARQP
                     TDRAVGYLAGRLGLDVADFEEPVTGSLAHALTLASSTGSADAIGALRAALAAEGHESAV
                     LRWQALWLLARAARLQGDHAAERADLDRLVALGDEVGSAELRVRGLTRLARCLRSLGEI
                     TPALDAAVAAHRLALGEDLGVEDRAAALLALVSVQAEAGQVPEARVHADELAALVAGRT
                     DALWAEAMWTAAAVRVRQGDHTGAQAFLDAALERFSSQEDLVLWLRLRLAAGRLHLQTL
                     PPDPARAEACAAQAEAALAFVGTPALRQDLTALKADLAFATGRYDDARALLGDLAGDEP
                     RMTYRDRVRLEILRQQLLILGGDASGVEGLRTLAQQAQADANIDLAAEIWRTLADALAQ
                     SRPAPAEPA"
     gene            10421..10549
                     /locus_tag="IE289_RS52955"
                     /old_locus_tag="GCM10010317_088400"
     CDS             10421..10549
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS52955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_088400"
                     /product="hypothetical protein"
                     /protein_id="WP_257040037.1"
                     /transl_table=11
                     /translation="MVSKKKNPAGNEPELSPAFGSEITDGPDEDTEMSVLGSIALQ"
     gene            complement(10666..11139)
                     /locus_tag="IE289_RS43020"
                     /old_locus_tag="GCM10010317_088410"
     CDS             complement(10666..11139)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521815.1"
                     /locus_tag="IE289_RS43020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088410"
                     /product="DUF1772 domain-containing protein"
                     /protein_id="WP_097281949.1"
                     /transl_table=11
                     /translation="METLVQTLAVVATMANAVVYGTDVFSAIVQRPALAHVDDAVLTST
                     MGQIHRFGDRRMPVPGVFGLLATVATAVAAGFGGRVTAAVAAAVAAAALVVWLAVYNKV
                     SAPVNKELTDAALDCRTAPNARGLQRTWDSVINARVVLQAVALGAMCVALVAS"
     misc_feature    complement(11204..11224)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.62"
                     /tool="antismash"
     gene            11372..12583
                     /locus_tag="IE289_RS43025"
                     /old_locus_tag="GCM10010317_088420"
     CDS             11372..12583
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521814.1"
                     /locus_tag="IE289_RS43025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088420"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190173722.1"
                     /transl_table=11
                     /translation="MALGRARRVLIAGGGIGGLAAALALQRAGLEPVVFERAEALRDGG
                     AGLHIWTNGVLALDCLGVAGQVLRTAPAQQVAHFSTHRGEVLGAWPVGDFVERYGAPTI
                     AVERSVLHSVLREALHGSPVRTGAHVTGFEQDEDGVTVRFADGGSERGDLLIGADGIHG
                     TVRDALFGPARNRYSGYIAWRGRSPLQHPDIPPGTFNAMFGPGTRFTYYDVAPGLVHWM
                     SVANGPAGGRDAPGVREMLLRRHRGWGGPVADILAATPEEGIIRGDVEGRSPERRWGQG
                     RVTLLGDAAHPITFNIGQGACQALEDALVLAEHLEHADDPIAALRRYERERRARTAPLQ
                     RIAWRIGRMGAVQNPLLIRAREAFMRKNWNTKAFAAAEKGQVAYGTRWAPARRPAPAPA
                     ATVD"
     gene            complement(13065..13661)
                     /locus_tag="IE289_RS43030"
                     /old_locus_tag="GCM10010317_088440"
     CDS             complement(13065..13661)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035527.1"
                     /locus_tag="IE289_RS43030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088440"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_180292654.1"
                     /transl_table=11
                     /translation="MVRMSADERRRSVIRAAVSEFARGGYDGTSTEAIARRAGVSQPYL
                     FRLFAGKRALFLAAARCCLADTARLFTEATEGLAGEEALRAMANAYTRVIVKEPERLLM
                     QMQVYVAVAAGEADGDAAFGEAVRAEWRRLWDTVHRPLGADTGQTTTFMAYGMLVNVLV
                     CLGFPPEDPLWDGLYPAARAGARQPGALQRRPAPG"
     misc_feature    13888..13902
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.22"
                     /tool="antismash"
     gene            13922..14890
                     /gene="fabD"
                     /locus_tag="IE289_RS43035"
                     /old_locus_tag="GCM10010317_088460"
     CDS             13922..14890
                     /EC_number="2.3.1.39"
                     /GO_function="GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_AT (7-290). E-value: 6.5e-64. Score:
                     208.1. Matches aSDomain:
                     nrpspksdomains_IE289_RS43035_PKS_AT.1"
                     /codon_start=1
                     /gene="fabD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521812.1"
                     /locus_tag="IE289_RS43035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088460"
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_190173723.1"
                     /sec_met_domain="PKS_AT (E-value: 1.4e-63, bitscore: 208.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDNLFTMFPGQGSQRAGMAGHLLREHPRTAGRVLARAEEATGLP
                     LTALCSTAPEEELAPTEIAQPAIVATSLAVLEVLRDQAGFVPAVVAGHSLGEYPALVAA
                     GVLEAEAALRLVRRRGELMAGVSRQVGGAMTAVLGLAAARIEEICADCAPLGVVEIANY
                     NEPGQTVISGQRPAVEEAARRALAAGAERAVALKVSAPFHCSLMRAIEDEFAAELERVR
                     FSAPRLPVISSVTGTLVRDGGHARDLLRRQLAGPVRWVDVLGAAAAHAVDGCLEVGPGR
                     VLSGFANRTGVHSVVRSTHDARRISALLRELGQEPAPGAAA"
     misc_feature    13926..13941
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.63"
                     /tool="antismash"
     CDS_motif       13943..13993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS43035_0001"
                     /evalue="1.30E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="IE289_RS43035"
                     /protein_end="24"
                     /protein_start="7"
                     /score="20.6"
                     /tool="antismash"
                     /translation="MFPGQGSQRAGMAGHLL"
     aSDomain        13943..14791
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43035_PKS_AT.1"
                     /evalue="6.50E-64"
                     /label="IE289_RS43035_PKS_AT.1"
                     /locus_tag="IE289_RS43035"
                     /protein_end="290"
                     /protein_start="7"
                     /score="208.1"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFPGQGSQRAGMAGHLLREHPRTAGRVLARAEEATGLPLTALCST
                     APEEELAPTEIAQPAIVATSLAVLEVLRDQAGFVPAVVAGHSLGEYPALVAAGVLEAEA
                     ALRLVRRRGELMAGVSRQVGGAMTAVLGLAAARIEEICADCAPLGVVEIANYNEPGQTV
                     ISGQRPAVEEAARRALAAGAERAVALKVSAPFHCSLMRAIEDEFAAELERVRFSAPRLP
                     VISSVTGTLVRDGGHARDLLRRQLAGPVRWVDVLGAAAAHAVDGCLEVGPGRVLSGFAN
                     RT"
     CDS_motif       14171..14293
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS43035_0002"
                     /evalue="8.20E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="IE289_RS43035"
                     /protein_end="124"
                     /protein_start="83"
                     /score="56.5"
                     /tool="antismash"
                     /translation="GFVPAVVAGHSLGEYPALVAAGVLEAEAALRLVRRRGELMA"
     gene            15084..15506
                     /locus_tag="IE289_RS43040"
                     /old_locus_tag="GCM10010317_088470"
     CDS             15084..15506
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (14-69). E-value: 8.9e-11.
                     Score: 33.9. Matches aSDomain:
                     nrpspksdomains_IE289_RS43040_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521811.1"
                     /locus_tag="IE289_RS43040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088470"
                     /product="acyl carrier protein"
                     /protein_id="WP_225900738.1"
                     /sec_met_domain="PP-binding (E-value: 5.1e-10, bitscore:
                     32.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETLTPTSTDYFSAVQAAIADALGIDEAEAVPEATLLGQLGAES
                     IDLLDILFRIERATKVKITVADIAALLQGGIPDEEFGDENEVVNDTGLTHLEKVLPQFD
                     RSQLSEPLTAEGVLGLFTVQNLTDLLTERAAAQHAA"
     aSDomain        15126..15290
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43040_PP-binding.1"
                     /evalue="8.90E-11"
                     /label="IE289_RS43040_PP-binding.1"
                     /locus_tag="IE289_RS43040"
                     /protein_end="69"
                     /protein_start="14"
                     /score="33.9"
                     /tool="antismash"
                     /translation="AVQAAIADALGIDEAEAVPEATLLGQLGAESIDLLDILFRIERAT
                     KVKITVADIA"
     gene            15637..16404
                     /locus_tag="IE289_RS43045"
                     /old_locus_tag="GCM10010317_088480"
     CDS             15637..16404
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-167). E-value: 2.6e-22. Score:
                     71.5. Matches aSDomain:
                     nrpspksdomains_IE289_RS43045_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521810.1"
                     /locus_tag="IE289_RS43045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088480"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_075032275.1"
                     /sec_met_domain="adh_short (E-value: 1.7e-46, bitscore:
                     151.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.4e-34, bitscore:
                     113.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDRTALVTGASRGIGRAIALALAEQGAAVAVNYRSRQEDAAA
                     VVKEIETAGGRAAAVGADVADPQQAARLVQEATRLLGPLDILVNNAGTSDDGLIYDAPP
                     DAWLNVMKTNFGGAWHCTHAVLEQFMARGDATIVNISSAMGERGWIGQANYSASKGALN
                     SFTRCAAVELARFGIRVNAVLAGFTPTELVDGVLQRDGGKSIKRQIPLRRFATADQVAA
                     AAVFLAGPDSGYTTGELLCVDGGFSAQLGIGRP"
     aSDomain        15655..16137
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43045_PKS_KR.1"
                     /evalue="2.60E-22"
                     /label="IE289_RS43045_PKS_KR.1"
                     /locus_tag="IE289_RS43045"
                     /protein_end="167"
                     /protein_start="6"
                     /score="71.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGASRGIGRAIALALAEQGAAVAVNYRSRQEDAAAVVKEIE
                     TAGGRAAAVGADVADPQQAARLVQEATRLLGPLDILVNNAGTSDDGLIYDAPPDAWLNV
                     MKTNFGGAWHCTHAVLEQFMARGDATIVNISSAMGERGWIGQANYSASKGALNSFTR"
     CDS_motif       15661..15729
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS43045_0001"
                     /evalue="1.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE289_RS43045"
                     /protein_end="31"
                     /protein_start="8"
                     /score="21.3"
                     /tool="antismash"
                     /translation="LVTGASRGIGRAIALALAEQGAA"
     misc_feature    15664..15679
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     gene            16438..16890
                     /locus_tag="IE289_RS43050"
                     /old_locus_tag="GCM10010317_088490"
     CDS             16438..16890
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521809.1"
                     /locus_tag="IE289_RS43050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088490"
                     /product="3-hydroxylacyl-ACP dehydratase"
                     /protein_id="WP_075032274.1"
                     /transl_table=11
                     /translation="MRFHLIDRIETCAPREHITARKVTSAEETYWQDTGDGPALPFGLA
                     LEALCQSATWLIMLSTDHRLRAALLAVGEATAHRPVRPGEVLRMHATVESMTEEAALLD
                     GTVTVDGENVLEASGILCALIDAERLDDPAATRRMAHQLQGGGPVG"
     gene            16887..18164
                     /locus_tag="IE289_RS43055"
                     /old_locus_tag="GCM10010317_088500"
     CDS             16887..18164
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (157-419). E-value:
                     4.6e-45. Score: 146.2. Matches aSDomain:
                     nrpspksdomains_IE289_RS43055_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521808.1"
                     /locus_tag="IE289_RS43055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088500"
                     /product="beta-ketoacyl synthase"
                     /protein_id="WP_190173724.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-40, bitscore:
                     132.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 8.5e-112, bitscore: 366.9,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRVAITGVGAVTPLGNDAGTTWQGLAAGRSGVGPLTTFDAAGFP
                     VRIAAQVKDFDPAAAIPARIGRKHLSRVGLFGVAAAWEALRSARAEDLGEEVYDPGERG
                     VAMGASVGRPELQALLDVGHLRATTGRADAFLCHPPAVTLTDDQNVPLSAMARMMSATG
                     PMIGISTACSGSGHAIGEAYRAIQEGDARLMVAGGYDSLTTWLDLLGFSLLGALTDRHN
                     DDPEHASRPFDADRSGFVIGEGAAAVVLEDLDAARERGAPVLGEVLGYGSTLNAWRITD
                     SPPDGSGAVQAMEAAIGESGLGTAGIDYVVAHGTSTHGNDQSETVAIKKVFADDARRLV
                     VSAPKSMAGHLTSASLGLGVLAALGAIRHSLVPPTVNLERPDRGLDLDYVPHTARPMPV
                     AAALINAFAFGGSNTSLVVGAPREDT"
     aSDomain        17358..18143
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43055_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.60E-45"
                     /label="IE289_RS43055_PKS_KS.1"
                     /locus_tag="IE289_RS43055"
                     /protein_end="419"
                     /protein_start="157"
                     /score="146.2"
                     /tool="antismash"
                     /translation="MMSATGPMIGISTACSGSGHAIGEAYRAIQEGDARLMVAGGYDSL
                     TTWLDLLGFSLLGALTDRHNDDPEHASRPFDADRSGFVIGEGAAAVVLEDLDAARERGA
                     PVLGEVLGYGSTLNAWRITDSPPDGSGAVQAMEAAIGESGLGTAGIDYVVAHGTSTHGN
                     DQSETVAIKKVFADDARRLVVSAPKSMAGHLTSASLGLGVLAALGAIRHSLVPPTVNLE
                     RPDRGLDLDYVPHTARPMPVAAALINAFAFGGSNTSLVVG"
     gene            18161..18670
                     /locus_tag="IE289_RS43060"
                     /old_locus_tag="GCM10010317_088510"
     CDS             18161..18670
                     /EC_number="4.2.1.-"
                     /GO_function="GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521807.1"
                     /locus_tag="IE289_RS43060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088510"
                     /product="3-hydroxyacyl-ACP dehydratase FabZ family
                     protein"
                     /protein_id="WP_190173725.1"
                     /transl_table=11
                     /translation="MTTTVPTAGPTPNPVSGAGSTTVTTGPVAGAESAAAAVPGGGPGG
                     FDRLLEAVVGERAAAVRNVPATLTCFTDHFPRHPVLPGVLLLESMAALARTAAGPGTWR
                     LAAVRGVRFKHFVGPGDQVHLTVEVSAHGPHRTECRATARAGGRVVATARVLALVSDET
                     TREGTA"
     gene            18667..19956
                     /locus_tag="IE289_RS43065"
                     /old_locus_tag="GCM10010317_088520"
     CDS             18667..19956
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (77-399). E-value:
                     2e-36. Score: 117.7. Matches aSDomain:
                     nrpspksdomains_IE289_RS43065_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266150.1"
                     /locus_tag="IE289_RS43065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088520"
                     /product="beta-ketoacyl synthase"
                     /protein_id="WP_190173726.1"
                     /sec_met_domain="t2fas (E-value: 1.5e-90, bitscore: 296.9,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.1e-34, bitscore:
                     112.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQRRRVMVTGIGLMTAIGQSAAETWHSLLEGRCGIGPLRAYDP
                     APLRTGIGAEIPSFTPAQWASRRTLRMLCRGDQLALAGATLALQDAGLDDGSDLGHRAG
                     LFLGSNKEMPRMDELIAQLQAVRADDGTPDLHRLGQSASSVIAPLFFVEGLQPAAAFHI
                     SEKYGIRGANAYFAGTADSGAMAIGRGMRTVRRGEADLVLAGGYDDATGWWAMSKMDGL
                     GVLSTRTDLGTEAFRPFDRDRSGSVFGEGAALLVLEEREHALARGARCYAEITGFGAGN
                     DCVRPPSPQPRARGLARAIGRALADAARPFPDGSYIAAHGCATQQGDASETVALHDALG
                     TAAKSAQISSVKPQTGHLVGGAGALNAAVAALALDSGTVPATLNLHHPAAECDLDYVPL
                     TPRHTRPDSALALARGLEGQAVAVALGRTS"
     aSDomain        18898..19863
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43065_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.00E-36"
                     /label="IE289_RS43065_PKS_KS.1"
                     /locus_tag="IE289_RS43065"
                     /protein_end="399"
                     /protein_start="77"
                     /score="117.7"
                     /tool="antismash"
                     /translation="QLALAGATLALQDAGLDDGSDLGHRAGLFLGSNKEMPRMDELIAQ
                     LQAVRADDGTPDLHRLGQSASSVIAPLFFVEGLQPAAAFHISEKYGIRGANAYFAGTAD
                     SGAMAIGRGMRTVRRGEADLVLAGGYDDATGWWAMSKMDGLGVLSTRTDLGTEAFRPFD
                     RDRSGSVFGEGAALLVLEEREHALARGARCYAEITGFGAGNDCVRPPSPQPRARGLARA
                     IGRALADAARPFPDGSYIAAHGCATQQGDASETVALHDALGTAAKSAQISSVKPQTGHL
                     VGGAGALNAAVAALALDSGTVPATLNLHHPAAECDLDYVPL"
     gene            20001..22370
                     /locus_tag="IE289_RS43070"
                     /old_locus_tag="GCM10010317_088530"
     CDS             20001..22370
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (88-414). E-value:
                     1.1e-52. Score: 171.4. Matches aSDomain:
                     nrpspksdomains_IE289_RS43070_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (475-728). E-value:
                     4e-13. Score: 41.0. Matches aSDomain:
                     nrpspksdomains_IE289_RS43070_PKS_KS.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ketoacyl-synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521805.1"
                     /locus_tag="IE289_RS43070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088530"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_190173727.1"
                     /sec_met_domain="t2fas (E-value: 1.8e-103, bitscore: 339.4,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.4e-39, bitscore:
                     127.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="Ketoacyl-synt_2 (E-value: 2.2e-09,
                     bitscore: 30.3, seeds: 28, tool: rule-based-clusters)"
                     /sec_met_domain="APE_KS1 (E-value: 6.1e-23, bitscore: 74.2,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVHDRAVRPDTAARPRTVVVCGVGAVTAQGEGAAALWEGIRAG
                     HSAIGPVTGMPMDGYGTAIGGEVPPLSRPAYDYLAAFGGSEREPAVDFALTAAAEALQQ
                     AGLAGLPAERWGVAFGSCNGGLRSAEKLARRSREGTTLPDDALHYLLVPPQAIAEALSA
                     AFALKGPALSVNTACASGAHAIAHAAEAIAAGRADAMLAGGSDAFTETAFAGFTSLQSL
                     SAKPAAPYSKDRDGLSLGEGAGMLVLAEESVARAAGAPVLAEVLGYGLSADGYHATAPH
                     PEGEGAARAIRGALKAAGITPGDVGYINGHGTGTPKNDSAESNAVRAAFGEAAQKTALS
                     SSKSMIGHLLGAAGAVEAIVTVKALVEQIAPPTANFTGTDPKCGLDAVPDTGRELAMNA
                     ALSNNFAFAGANACVAFGWPSGRRFTVPAPPAAEKVVITGGAALTPAGEGLEALWEAWR
                     QGRRLGADEDGLRVARAVFDPAAHIGARDRRRMDRLSQLAVASCRAALAHAGLKADEHT
                     GVVLGTGLGPMRSIEDFLLPVLGGCPAHGSPAVFPNTVFNAAAGQVAMHVGAKGPTSTV
                     TTGHAAGASALTVAHDLLLQHRAEAVLCPAVEDLSPGVLAAYRQLPLFGDAGYTLAEAG
                     IALVLERESSARARGARILAEFAGHAAAGDAAGIGRWNAQGEGVERAMRAALAHAGLTP
                     GELTGIWANAAGLTRADTPEALATGRLAAEARCPVHTPKQTLGEPVGAGAQLAALLALT
                     AWTTPASGAAAGPVLINSSSLGGTHISLVLRPATEN"
     aSDomain        20265..21242
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43070_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.10E-52"
                     /label="IE289_RS43070_PKS_KS.1"
                     /locus_tag="IE289_RS43070"
                     /protein_end="414"
                     /protein_start="88"
                     /score="171.4"
                     /tool="antismash"
                     /translation="PAVDFALTAAAEALQQAGLAGLPAERWGVAFGSCNGGLRSAEKLA
                     RRSREGTTLPDDALHYLLVPPQAIAEALSAAFALKGPALSVNTACASGAHAIAHAAEAI
                     AAGRADAMLAGGSDAFTETAFAGFTSLQSLSAKPAAPYSKDRDGLSLGEGAGMLVLAEE
                     SVARAAGAPVLAEVLGYGLSADGYHATAPHPEGEGAARAIRGALKAAGITPGDVGYING
                     HGTGTPKNDSAESNAVRAAFGEAAQKTALSSSKSMIGHLLGAAGAVEAIVTVKALVEQI
                     APPTANFTGTDPKCGLDAVPDTGRELAMNAALSNNFAFAGANACV"
     CDS_motif       20505..20552
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS43070_0001"
                     /evalue="7.70E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE289_RS43070"
                     /protein_end="184"
                     /protein_start="168"
                     /score="12.1"
                     /tool="antismash"
                     /translation="GPALSVNTACASGAHA"
     aSDomain        21426..22184
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43070_PKS_KS.2"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.00E-13"
                     /label="IE289_RS43070_PKS_KS.2"
                     /locus_tag="IE289_RS43070"
                     /protein_end="728"
                     /protein_start="475"
                     /score="41.0"
                     /tool="antismash"
                     /translation="VFDPAAHIGARDRRRMDRLSQLAVASCRAALAHAGLKADEHTGVV
                     LGTGLGPMRSIEDFLLPVLGGCPAHGSPAVFPNTVFNAAAGQVAMHVGAKGPTSTVTTG
                     HAAGASALTVAHDLLLQHRAEAVLCPAVEDLSPGVLAAYRQLPLFGDAGYTLAEAGIAL
                     VLERESSARARGARILAEFAGHAAAGDAAGIGRWNAQGEGVERAMRAALAHAGLTPGEL
                     TGIWANAAGLTRADTPEALATGRLAAEARCP"
     CDS_motif       21711..21755
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS43070_0002"
                     /evalue="4.20E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="IE289_RS43070"
                     /protein_end="585"
                     /protein_start="570"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="GPTSTVTTGHAAGAS"
     gene            22373..23506
                     /locus_tag="IE289_RS52960"
                     /old_locus_tag="GCM10010317_088540"
     CDS             22373..23506
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521804.1"
                     /locus_tag="IE289_RS52960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088540"
                     /product="3-oxoacyl-ACP synthase III family protein"
                     /protein_id="WP_190173728.1"
                     /sec_met_domain="fabH (E-value: 3.1e-42, bitscore: 137.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHTSTAPPAEPRARHVSVLATGAHLPGEALDNDALARFCGPLPA
                     DVLDGIQVKRRHWMVDPATGTHTTSTSQMATAAARQALERAGVQADEIDLIVLSTASPD
                     YLLPVAATYVQQQLGLEDCAVIEVRAGCVGAVQAHDIARRLLADGTYTTALVIGAEAVS
                     PLLAPVFLGRDPERVRMRDRLTVYTFGDGAGALVLRAGEEGSAHGRRRPVFATRSLGGA
                     RKPGMLIVGGGTDAPLAEQQRRPRLMDIRLDIPGTAQFGPRVFVEGIHDLLTRSRLALA
                     DLDACVLPEGNAEYFASEYAAAGLSAADQAALSKTIVENLTDVGATGSAAVPLALDAGW
                     REGRIRPGDTVLLLAIEASRYLYAGLTLTWDAPFPGH"
     gene            23586..24452
                     /locus_tag="IE289_RS43080"
                     /old_locus_tag="GCM10010317_088550"
     CDS             23586..24452
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521803.1"
                     /locus_tag="IE289_RS43080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088550"
                     /product="ester cyclase"
                     /protein_id="WP_190173729.1"
                     /sec_met_domain="PF07366 (E-value: 5.6e-34, bitscore:
                     109.7, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIQETERTARSVEERNKKTIRRVFDAFVNQGDFSVVDEIYSPDM
                     IDHQPLPGAPEGLEGVRYTIAGLREGFPDLHVTIEDMSAHGDHVVIHNTWRGTHLGDFL
                     GAPPTGQAIEFTGVVVWRLLADGLIAERWGIGVESNMLAVLGLRRLAPAARNGARAAAR
                     RTVTSAGALLPLPPGAAGAWHALQAELAGARLRAYEASRRRAGILQESFALQPLGGQDV
                     LVHRIEARDPQGAARRLAASADPFDSWLRQEAAAVLGTDPWTHLAANATPAGHTWMPVT
                     SELTTAD"
     misc_feature    24517..24529
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.88"
                     /tool="antismash"
     gene            24590..25582
                     /locus_tag="IE289_RS43085"
                     /old_locus_tag="GCM10010317_088560"
     CDS             24590..25582
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521802.1"
                     /locus_tag="IE289_RS43085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088560"
                     /product="aldo/keto reductase"
                     /protein_id="WP_190173802.1"
                     /transl_table=11
                     /translation="MRQRKLGSQGLEVSEQGLGCMGMTFAYGPADDQEALRTAHRALEL
                     GVNLLDTADFYGPHSNEEFVARVIAGRRDSITVSSKVGNEVTADGTITGRLNGRPDYIR
                     TSIDATLRRLGTDRLDLYYLHRVDPAVPVEESTGALADLVTAGKVRHLGICEASAATIR
                     RAHAVHPLTAVQTEYSLSTRDVEANGVLAAVRELGIGFVGYSPLGRGLLTGAIRSLDAL
                     AEHDFRRVVPRFQQGNLERNLHVVERLQALAAAKQITAGQLALAWVLAQGDDVVAIPGT
                     KRVTYLEENLAASTVELSAADLAALDEIAPHGSTAGDRYPVGAMATLDG"
     gene            25633..26814
                     /locus_tag="IE289_RS43090"
                     /old_locus_tag="GCM10010317_088570"
     CDS             25633..26814
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991152.1"
                     /locus_tag="IE289_RS43090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088570"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_190173730.1"
                     /sec_met_domain="DAO (E-value: 8.9e-09, bitscore: 28.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANITIIGGGLAGLTAAISAAEQGARVTVHEAHSHTGGRARSAAG
                     PYVTNDGPHTFFDNGDAWHWLLQRGLAGRYVRLSFHEWTRMRFRHQGRLRMTLPSGYMK
                     MTWRHRGIEVPVDRSFQDWASERFAQQTVNEALGFLGPILFDGDPGRLSAAFVWERLLR
                     VGTPRFPLPSRYFIGGWGALIERMERVARARGVVIETGSRLSELPADGPVIVATSLASA
                     RSLLSDPGLEWPSGTAALLDMAVTHSKKDGNVSFDMDEGGFTSQYSDHDPSLAPKGQAL
                     FQGQMPLRPGESKADALARLEKLFDLTTPGWRTRLLWRREGVSRGRTGALDLPGLSWRD
                     RPAIDRGDGVYLAGDSVAAPGILAETSINSALRAARLAVHTRPAAHRSAALGR"
     gene            complement(26892..28082)
                     /locus_tag="IE289_RS43095"
                     /old_locus_tag="GCM10010317_088580"
     CDS             complement(26892..28082)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020477415.1"
                     /locus_tag="IE289_RS43095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088580"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_190173731.1"
                     /transl_table=11
                     /translation="MTTHVKRAFKYRFCPTDAQAAELSRTFGCVRKVYNMALAARTEAW
                     TRQERVNYNQTSAMLTAWKKTEELAYLNEVSSVPLQQALRHLQTAFANFFGKRAKYPRF
                     KSRKKSRKSAEYTNSAFRFRDGELQLAKMSEPLRIVWSRPLPEGVNPSTVTVSQDAAGR
                     WFVSMLCDDPGIRHLPATDAAVGIDAGLDHLLTLSTGEKITNPHHERRDRAALAKAQRR
                     LAKKQKGSANGVKARRKVARIHARIADRRRDSLHQITTRLVRENQTLVIEDLTVRNMVK
                     NRKLARVISDAAWREFRSMLEYKAQWYGREVIAVDRWFPSSKLCSACGTLQDKMPLNVR
                     TWTCNCGATHDRDVNAAKNLLAAGRAVAACGAGVRPQRSSPGGQSAMKQEVSRREP"
     misc_feature    28050..28061
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(28078..28095)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.33"
                     /tool="antismash"
     misc_feature    28237..28252
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.68"
                     /tool="antismash"
     gene            28238..28891
                     /locus_tag="IE289_RS43100"
                     /old_locus_tag="GCM10010317_088590"
     CDS             28238..28891
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521800.1"
                     /locus_tag="IE289_RS43100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088590"
                     /product="thermostable hemolysin"
                     /protein_id="WP_075032267.1"
                     /transl_table=11
                     /translation="MRITLSERGTPDWQTAADLARLVFAKQYQASISPDPDGFLAFFET
                     AADGQEEVLACAGLSFPEEESILLERYLDAPVEDVITRAVGAPVKRSQVLQIGSIASVR
                     AAAGAEIIKAIPLIMACLGRPYAVMTMTGRLAALMQRLGCVFHPLADASAERLPEGERA
                     AWGSYYDTRPVVGYAEAAEQSTLLLAAIGRYCFTSVDMRLLSNRPQQGVLTRAA"
     gene            28881..30506
                     /locus_tag="IE289_RS43105"
                     /old_locus_tag="GCM10010317_088600"
     CDS             28881..30506
                     /NRPS_PKS="Domain: AMP-binding (27-424). E-value: 6.3e-66.
                     Score: 214.6. Matches aSDomain:
                     nrpspksdomains_IE289_RS43105_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521799.1"
                     /locus_tag="IE289_RS43105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088600"
                     /product="AMP-binding protein"
                     /protein_id="WP_190173732.1"
                     /sec_met_domain="AMP-binding (E-value: 5.5e-67, bitscore:
                     219.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPDTPTRLSLAQGLLERAGSDAVMVRVLAADGSAPAAWSYRDLT
                     GAALTLAARLQEQAQALGRPARVGLLAENSPEWVAADLAALFAGAVEIPVPTAFTAQQA
                     ASLLQSADLCLTDSAGEAALARWRTSTPQPVLPDGCPAVALDLPALARAPRPAAPPQIP
                     AHDQIVKVIHTSGTTSAPKGVQIRRHGLDELLTSLRARTRPEIFERYLSIVPLSLLIEQ
                     VAGLYMPFLAGGSVSFLPPGTALVGTAADAAPRMLTLLRAARPTALVVPPTVAGLFLAL
                     CDQQPAESVTERHRRIFGHDGPVFIACGGAPVPPEILQRLDAYGLTVHEGYGLSENSSV
                     VSWNFPGAVRFGTVGRPLDHVRAELAEDGELLIRSTSLFAGYTREDPSSVVVDDQGRLH
                     TGDLAEIDADGYLRITGRKKNLVITAGGRNVAPEWVEARYRELGFVREAAVVADGLDQV
                     HGLFVIDAGLDPQAARREITDFGRHKLSGIERAAVVHLMSEDDPAYATCFTVTGRPRRD
                     VVRAHVLKQPRTPAPRGGETKEKA"
     aSDomain        28962..30152
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43105_AMP-binding.1"
                     /evalue="6.30E-66"
                     /label="IE289_RS43105_AMP-binding.1"
                     /locus_tag="IE289_RS43105"
                     /protein_end="424"
                     /protein_start="27"
                     /score="214.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="VLAADGSAPAAWSYRDLTGAALTLAARLQEQAQALGRPARVGLLA
                     ENSPEWVAADLAALFAGAVEIPVPTAFTAQQAASLLQSADLCLTDSAGEAALARWRTST
                     PQPVLPDGCPAVALDLPALARAPRPAAPPQIPAHDQIVKVIHTSGTTSAPKGVQIRRHG
                     LDELLTSLRARTRPEIFERYLSIVPLSLLIEQVAGLYMPFLAGGSVSFLPPGTALVGTA
                     ADAAPRMLTLLRAARPTALVVPPTVAGLFLALCDQQPAESVTERHRRIFGHDGPVFIAC
                     GGAPVPPEILQRLDAYGLTVHEGYGLSENSSVVSWNFPGAVRFGTVGRPLDHVRAELAE
                     DGELLIRSTSLFAGYTREDPSSVVVDDQGRLHTGDLAEIDADGYLRITGRKKNLVIT"
     CDS_motif       29391..29438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS43105_0001"
                     /evalue="8.60E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="IE289_RS43105"
                     /protein_end="186"
                     /protein_start="170"
                     /score="15.4"
                     /tool="antismash"
                     /translation="VIHTSGTTSAPKGVQI"
     gene            30835..31743
                     /locus_tag="IE289_RS43110"
                     /old_locus_tag="GCM10010317_088610"
     CDS             30835..31743
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (26-292). E-value: 1.3e-36. Score:
                     118.7. Matches aSDomain:
                     nrpspksdomains_IE289_RS43110_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521798.1"
                     /locus_tag="IE289_RS43110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088610"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_190173733.1"
                     /sec_met_domain="TauD (E-value: 2.8e-36, bitscore: 118.7,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAMKTTPYGTGSGLLVEPAGPGGLDGVDPKELRDLLSQAGFLL
                     LRGFGADMDAFTALVQHTSTSTTLDPARDFYSEVAQKVDAGFDEVGLHTENGNSPFRSH
                     LAWFFCEKAASSGSQTTVCDGYRVWDALSPQTRTAFAAQDIVYSRYVAEPQWRAMAHHL
                     LGRTKPADEIDVEELLALAGQLPGTEIVPQDDGGVRYSFTTPAAGTTVFGPRPSFANSI
                     LGPSFNYEKPTITFADGTALSPQLLAEVEEVTARLTENLDWQDGDAAVIDNTRVMHGRR
                     AITDPDRTIYNALSYIEAPAA"
     aSDomain        30913..31710
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS43110_TauD.1"
                     /evalue="1.30E-36"
                     /label="IE289_RS43110_TauD.1"
                     /locus_tag="IE289_RS43110"
                     /protein_end="292"
                     /protein_start="26"
                     /score="118.7"
                     /tool="antismash"
                     /translation="DGVDPKELRDLLSQAGFLLLRGFGADMDAFTALVQHTSTSTTLDP
                     ARDFYSEVAQKVDAGFDEVGLHTENGNSPFRSHLAWFFCEKAASSGSQTTVCDGYRVWD
                     ALSPQTRTAFAAQDIVYSRYVAEPQWRAMAHHLLGRTKPADEIDVEELLALAGQLPGTE
                     IVPQDDGGVRYSFTTPAAGTTVFGPRPSFANSILGPSFNYEKPTITFADGTALSPQLLA
                     EVEEVTARLTENLDWQDGDAAVIDNTRVMHGRRAITDPDRTIYN"
     gene            31849..33330
                     /locus_tag="IE289_RS43115"
                     /old_locus_tag="GCM10010317_088620"
     CDS             31849..33330
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521797.1"
                     /locus_tag="IE289_RS43115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088620"
                     /product="MFS transporter"
                     /protein_id="WP_190173734.1"
                     /transl_table=11
                     /translation="MTTDHTAAPRTTDTAPAAADPRRWRLLVFVALAQFMVLLDTTVVN
                     LALPAIQADLKAGATAVEWVLTAYILCFGGLMLLGGRTADRWGRRRTFLLGALLFTAAS
                     LLCGLAQGAGLLIAARALQGCGAAFLSPAAMSLVTTTFPKGRERTTALAVWAALAGLGG
                     TLGVIAGGLITDSLSWRWIFYINLPFGIVAVAGVLLLSRGRPETRIRGSRPDIAGAVTV
                     TAGLAALVYAIVNIQDHGAASTPYVLAPAAASLALLAAFVLIERRTPDPLMPLHLFATR
                     SLATAGLGRVLTSGVQASVLFLCSYYLQRTLGYSTLKSGFAFLPLGVVAILVTAPATRI
                     MHKAGPRPVYLAGAAGSVLGLLLLTQAPQNGTYLLHLLPALLILGASMQCCGIPVNVHG
                     VSDIPARQQGIASGVLVAAFQVGASLGVATVATSALTRTTHDLTHHTAPALAWLDGLHL
                     GFWIATGIGVLNLLTAYFGLPRHRRAPAPAGPRTA"
     gene            33367..33936
                     /locus_tag="IE289_RS43120"
                     /old_locus_tag="GCM10010317_088630"
     CDS             33367..33936
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521796.1"
                     /locus_tag="IE289_RS43120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088630"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_190173735.1"
                     /transl_table=11
                     /translation="MARPGDTLHLGKDKLTFLTTAAETDGAFVEVEVEYAPAVIKPPQH
                     YHPRQTEHMRLQSGRLHLQLDGVLHEYEQGADFYIPPGAVHSMWNPGPEPTRVIWRTTP
                     AYRTETVFETLWGLTNEGRLRPDGTPRLQMPLLALAFRDEYRVVTGRPYPLDTALCLLL
                     SPLSLACGYRPTYRPPQNTATLQPTA"
     gene            34043..34513
                     /locus_tag="IE289_RS43125"
                     /old_locus_tag="GCM10010317_088640"
     CDS             34043..34513
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521795.1"
                     /locus_tag="IE289_RS43125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088640"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_190173736.1"
                     /sec_met_domain="PF07366 (E-value: 6.2e-12, bitscore: 38.5,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATEAHEFTLPGADLPQPDAELRKKREAVVLQHTVAEIAWDIDGV
                     LATFPRGGVYRIQAFEEGPLIGEEAIKKGYFADLKAAFPDLEHELHHVHHTPTAVILEA
                     QARGRQEADWRGIPNRGKSIDAPVAVFFHFDGDVLIDETLYFDIATFQRQLA"
     gene            34755..36218
                     /locus_tag="IE289_RS43130"
                     /old_locus_tag="GCM10010317_088650"
     CDS             34755..36218
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383112.1"
                     /locus_tag="IE289_RS43130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088650"
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="WP_190173737.1"
                     /transl_table=11
                     /translation="MSTVNPPSPGGETRRVVFWAILTTSLASFMAGLDNLVIITALPTI
                     REKLGGSLTDLEWTVNAYTLSFAVLMMFGAALGDRFGRRKVFSLGLLLFTAASAAAALA
                     PGINELVAARAVQGVGAAIIMPLSVTLLTAAVPAEKRGAALGIWGAVNGLSIAAGPLVG
                     GAIVEHLSWQWIFWLNVPIGLALAPLSFRKLAESRIAHSRLDAVGTALASLGLFGIVLG
                     LIKGHGDGWTSPQVLGALIGGTAVMALFVVWENRTEHPMVPMRMFRNRAFTAINLAGAL
                     MSVGMFGAIFLMTQFLQNIQGYTAMQAGVRLLAWTAMPMVVAPIGGMVSDRIGGKPVVT
                     LGLAMMTAGMVYWAFVLKPDVSYAAQLPSLMICGAGMALFYAPLMNLTMGSVAEHEQGI
                     ASGVTAATREVGAALGVALLASIFSANGGYASPRNFVDGLVPAMWVGATAVALATFAML
                     LAPSRRRAAASAPVAQAAPAQESAPAPLH"
     gene            36313..36927
                     /locus_tag="IE289_RS43135"
                     /old_locus_tag="GCM10010317_088660"
     CDS             36313..36927
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521596.1"
                     /locus_tag="IE289_RS43135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088660"
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="WP_190173738.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.8e-48,
                     bitscore: 157.4, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIEEMKVRDAFRITPSQLPDNRGLFFEAWRLGGLTAASGQPFTV
                     RQVNFSVSRRNTLRGIHGTTLPPGQAKLVTCVRGAALDVVVDLRVGSPTFGMFDTTLQE
                     AGSGIGVYLADGLGHAFLALSDDTCMNYLCSQEYVPGTMVDIQALDPDIGIPWNTTGQL
                     IRSDKDTHAPSLSEAAARGLLPTYEQALASYHTAAPAGRRP"
     gene            complement(37139..38359)
                     /locus_tag="IE289_RS43140"
                     /old_locus_tag="GCM10010317_088670"
     CDS             complement(37139..38359)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054293.1"
                     /locus_tag="IE289_RS43140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088670"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_190173739.1"
                     /transl_table=11
                     /translation="MTTPMEADGAGHARYTYRLRVSSSARTALEAEWARCRWIWNECVA
                     KSKAVHLHHKTTGEKRTCGPAQLDKMLTGARERTPWLREGSSVPQQQLIRDFGKSRAKA
                     HKDIRERLPQRQRAGMPRWKKKREALPTLNYTRRGFRLKDDRLHLAGGIVLTVVWSRDL
                     PGEPSSVRVYQDSVGHWYASFVVPTEVQPLPETGRMLGVDWGVKETATTTSNAHDLPHA
                     QHGRKAQAGLTRYDRMMARRRPKKGQAASKGYREAKKWRAKTYAKIARQRQDTGRKWAK
                     KAVVDHDAIAVEDFRPKFLARSSMARKAADAAIGATKKALIEMGRKHGRDIRLVHPAHT
                     TMDCASCGARTKHALPLSERTYTCTACGVVSPRDKNSARVMLVRAGLNPAGAEGVRPPG
                     APLPEAA"
     gene            38377..38583
                     /locus_tag="IE289_RS53280"
                     /old_locus_tag="GCM10010317_088680"
     CDS             38377..38583
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009294498.1"
                     /locus_tag="IE289_RS53280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088680"
                     /product="Arc family DNA-binding protein"
                     /protein_id="WP_143604152.1"
                     /transl_table=11
                     /translation="MIRFSLRIPADLHEQVTARAAADRRSLNSEILHLLEVALTAPRPD
                     AGSPSGDPASPAPLRGKPDSSPA"
     gene            38611..39057
                     /locus_tag="IE289_RS43150"
                     /old_locus_tag="GCM10010317_088690"
     CDS             38611..39057
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265056.1"
                     /locus_tag="IE289_RS43150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088690"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_190173740.1"
                     /transl_table=11
                     /translation="MIECVRAVLVTPAGRLLLIRRTWPGATPYRVFPGGHVEPDDPGLR
                     AALVREIREETGAEPQITGLLHMLADAHQRQYFYLARIRSWSEADRTGPEFADPDRGEY
                     RLEEVPLSVQALDALSLEPEEIAALLRAAVTAGTELAALADPAR"
     gene            complement(39328..39945)
                     /locus_tag="IE289_RS43155"
                     /old_locus_tag="GCM10010317_088700"
     CDS             complement(39328..39945)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS43155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_088700"
                     /product="hypothetical protein"
                     /protein_id="WP_190173741.1"
                     /transl_table=11
                     /translation="MCVFDGVGFGFGVYLWVFDGVGVGFGVYLCVFDGVGFGFGEYLWV
                     FDGVGFGEYLWVFDGDGFGECLVVVVGDGLVVVVGDGLVVVVGVGAVVVVFDVSGADVE
                     GVAAGAAGCWDPVAAIAVPPAVPPDSRAAVRVPTAKVRPQWLRNVSFTMFSHLEQLPHW
                     SLSASTEVRSVPPDRRPEQTGSHFQQKWRVPVRGRTPRAGRS"
     gene            40179..41510
                     /locus_tag="IE289_RS43160"
                     /old_locus_tag="GCM10010317_088710"
     CDS             40179..41510
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IE289_RS43160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GCM10010317_088710"
                     /product="hypothetical protein"
                     /protein_id="WP_190173742.1"
                     /transl_table=11
                     /translation="MCAVVLAAAGAGAVALKTRHPAQAPGAVLTFRSVLNTFYLPRYTA
                     PGHAPWAPEYRIRLAAAAAPSRGSQGSARQVEADFDLSVFKGKADIWGENKGYGCARSG
                     FRVTCALPDIKYGEGADFLPFQVKPKPGTALGPAGSIVVTVHSADAPTIRHTTRVTVGS
                     PYLTTRNRKLTGVRPGGEVRLTPAFGNRGDTGVDGGITVVVVADGSTLLPRYGNCRYNK
                     AAAATEAQCDFPGPLPAGTAYETDHPVIAVTGQDTRSGSLHYSVWPTADIDGPSQLPGR
                     AVRGTGEVLRLRPVNGGAFTGSESRRSRGAAGAVDFETTRVDDVEAVGFTIRGRVGEEV
                     RTEVPYPRGYRGDTMWVTLPDGVSLVTRPPQDLQSEDSYCRKGPAKGGPVACGPGAEPY
                     AVVLLVRIDKRVEGARGSVTVPPGPAADPDQDNNTAPVTVEYIP"
     gene            complement(41538..42011)
                     /locus_tag="IE289_RS43165"
                     /old_locus_tag="GCM10010317_088720"
     CDS             complement(41538..42011)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982226.1"
                     /locus_tag="IE289_RS43165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_088720"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_190173743.1"
                     /transl_table=11
                     /translation="MDARLNLFGNPVAGKVLRHINSAGKAVSDAALPAATQELVKIRAS
                     QINGCGFCTDMHTKDAAHAGETPVRLNLVAAWREATVFTDAERAALELTEQGTRIADAA
                     GGVTDEAWANAAKHYDEDQLAALVSLIALINAYNRVNVLVRQPAGDYQPGQFG"
     misc_feature    complement(42293..42307)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 accgtgctgc cccgcagggc gctggtcagc gtgcccggac ccgcagcccc cgcagacccc
       61 acggacgccg cagcccccgc agaccccacg gacgccgtag acgccgtagg ccccgcagac
      121 gcaggggacg cggcagacgg cgcggacggc gtggaggaca cggacggcac ggacggcgtg
      181 gagggtgtgg gtgtggtgct ggtcgtggag gaggcgcctg ccgtcccccg cgtcccggcc
      241 cgcacgggcc cgccgccggg cacgcgtccc gcggaactgg tgctgctgtc cgccgcgacg
      301 cccgcgcacc tggcggccac cgccggccgc ctcgcggccc gcctgtccga cggcgacggc
      361 ggcggtggcc gggacggcgg cccggcggcc ccggatctcg ccgcggtcgc gcacgaactg
      421 cgcctggggc gggcggtgtt gcgctgccgt ctggcggtga ccgtccgcac ggtcgccgaa
      481 ctggccgacg cgctggccgg cttcgccgcg caccccggcc cgggcaggag cccggcgggc
      541 gtgcgcagcg ccgacctgcg caccgccgcg ggcccgccgc tgatcgaggg actcgaggag
      601 acccgcgcct atgtggccgc tctgtggcag ggcggccgcc tggagcagct gacacggctg
      661 tggctggccg gggtcgacgt ctgcgccgtc ctgcccgcgc atcccggccc ggccgccgtc
      721 gagctgcccg ccaccgtgct gcggccccgc ccgctggagc ccggccccgg cacggacgga
      781 gcaccgcagt gaccacccgc cccgcacccc cgaccacccc cgccctcatc cccgcccccg
      841 aacccgggcc cgcccccgct tctggtgcgg ggggcgggga gccggtcaag ctgtggctgt
      901 gtcccaacga cggcctgccg ccggaggtcg ccggcctgct cgccacgcac tggctggacg
      961 cgcaggagca gaagaccgcg agccgcttcc tgttcgaacg cgaccggcgc cagtaccttc
     1021 tggcccacac cctggtgcgg cgcgcgctgg cgctggaggc gggcctggcc gaggcggagc
     1081 tggtcatctg gcgttccgcg cggggacggc ccttcttgcg gcccgccgcc gcgggagggc
     1141 cgcgcggcgg gtcccagctg gacttcaacc tctcccacgc gggcggctac agcctgctgg
     1201 gcatcgtgcg ccggcaccgt atcggcgtgg acgtggaacg gctggaggac cgggacgagc
     1261 gggccatcac caccatcgtg cgcaccttcg ccgccccgga gcgggaatgg gtcgcgcgcg
     1321 ccgccgacgg gccggcccgc gaccggcgcg cgctgcgcgt gtggaccctc aaggaggcct
     1381 actccaaggc ccggggcctg ggtctcgggc tgcccttcga cgcgttcgcc ttcacgctgg
     1441 acgacgaacg cggcgtacgc gccttcaccc cgccggccga cgacacggcc cgcccgtggc
     1501 ggttcgtcga actggagccg gtgcccgatg tgctggtcgc cgtcgccgtc cccgccgacg
     1561 aggcccagga cccggtcctg cacctcggct acggcttccc ctggagccgc gcggcactgc
     1621 gcagcttccc gctgccccgc ccggtgggcg gacacccctc ggcactcccc gcgtaaccgg
     1681 ggcccgggcc gcgatcagcc cgggccggga gaacggctcc gagcaccggg tcctggcccg
     1741 acgggccgtc agtgacccgc ccggggtggc ctgctgcgtc tgctaccgga ctctttgcgc
     1801 agtgctccag ggttcagcct gggggtgaag cgcatcctgt ggctgcgacg cggagtgtcg
     1861 tggtgccggg tggggtgggc gcggagcgct cgcagggctg ccgggcggag ccggggagtg
     1921 cttcgtccgg gccggtgttg cccgtatggc agcagtgcgg aagtgttccg gcgaggctgg
     1981 gttcggctga tcgggtcggg ttgtcggtgg tgggtgttag cgtccggatc atgcagcttc
     2041 ggtatgcctt ccgcctcgac ccggagcccg gtcagcgcgt tgcgctggcg cgggcgttcg
     2101 ggtgcgcgcg ggtggtgtac aacgacgcgg tcgccgcccg ggagcgggcc cggcgggagg
     2161 gtgctgcgtt tccgagtgcg ggcgcgctgt cgaagacgct gatcaccgag gcgaagcaga
     2221 gccccgagcg gcagtggctg tccgaggtgt cggcagtaat cctgcagcag gcgctgcggg
     2281 acatggagcg cgcctacacc aacttcttct cctctctgaa aggatcccgc ccgggggcac
     2341 gggtgggggc gccgcgcttc aagccgaagc gggatgcccg ccaggcgatc cggttcaccg
     2401 cgaacgcccg atggaagatc accgaggcgg ggcggctgct cctgccgaag atcggcgagg
     2461 tgaaggtgcg ctggtcacgc aggctgccct cggtcccgtc gagcgtgacg gtgatccggg
     2521 acgcagcggg gcgattcttc gcctccttcg tcgtggcgac cgaccccggc gccgacctgg
     2581 cgcggatgcc cgaagccgac aatctgccca gcgtgggcat cgatctgggt ctcacacact
     2641 tcgcggtcct ctccgacggc cgtgtcatcg actccccgcg cttcctgcgc cgggcggaga
     2701 agaaactgaa gaaggtccag cgggagttgt cccgcaagca gaagaggtcg aacaaccggg
     2761 agaaggcccg tctgaaggtg gcccgtgcgc acgcgcaggt cgccgacgcc cgccgcgagt
     2821 tccaccacca gctctccacc cgcctgatcc gcgaaaacca agcggtcgcg gtggaggacc
     2881 tggcggtgaa agccctcgcg cgcacccggc tcggcaaatc cgtgcacgac gccggctggg
     2941 cgcagttcct cgcgatgctg gagtacaagg cacagcggta cgcccgcgtc tttgtgaagg
     3001 ccggccggtt cgagcccacc agccaggtgt gctcggtctg cggagtcaag gacgggccca
     3061 aacccctgca cgtgcgtacc tggacgtgca cgcactgcgg cacggtccat gaccgggacc
     3121 acaacgccgc caagaacgtc aaacaggccg ccggactggc ggtgacagcc tgtcgagcgc
     3181 aggtaagacc ggaactcgtt ccggcacaac gcgaagaagc aggaagccac ggaatccaca
     3241 ccggaactcg tgccgcgcag cggcacagca cccggtgagg aaggccagaa tctccctgct
     3301 tcagcaggga gagcaagtca acaccacccg ctcgtcgggg acctcaccct cggcttcgaa
     3361 gccttcacac ccatcggcga ccccgaccag acgctcggcc tgtacaccgt cgaacccgga
     3421 tcaccatcgg agaacgccct gtgcatgctc gcgagctgga ccgccgacaa cacgcacatc
     3481 cagcccgaaa aagccgccgg gcacgagcac tgacccggct ctcaccccgc ctgcggccgg
     3541 acgtgtcccg gcagaagcca ccgcggaaac caggcccccc cgttcgggac cgtcgtcctt
     3601 gccgggaaat ggcaggttgc gggcgcggac acccgcaccg cccgccccgc ccgcacgggc
     3661 tgcaggggct gaggccggtg cgggggcgcg ggggtgcgcc gatctccagc gggtttcgaa
     3721 ggggtctcga gcccggccgc cgaccgtggg gcatccggac atccgctgtt cgtgccgtct
     3781 gccgccggga ggtcgtgccg tgcccatcct caggtatctg gagagcccgc tggacgacct
     3841 gctgcggcgg gccgcggccc gtgacgcaaa cgccccggcc ctcaccgtgg ccgggacagg
     3901 ggccggggtg acgttcgcgg ccctggaccg ggaggcggac cgtatcgccc actacgtacg
     3961 gcgcgccgcg ggccgggccg gcgccgtcgt cgccgcggcc accaccctcg atgcggtctt
     4021 ccccgccgtg tactacggca ccgtccgcag cggccacccg ctcgccctgc tcgacccgct
     4081 gatggggccg gccgccctgt acgaggtgtg ctcggcggcc ggggccgaga tcgccttcgt
     4141 acccgccgcg ctggccgggc tgctcgccgg gctcggtgac cggctgcccc tgctgcacac
     4201 cgtcgtcctc acggacaccc cggcggacgc ggcaacggac cggccggcgg gcggggcagc
     4261 aggtgcgggc gggggtgtgc cgctggcgcg ggcgctggcg tcggtgcccg ccggtgtgcc
     4321 cgcgcggaca ccggcgccgg gggtggacgc ggtggcgtgc ctgcagttcg ccccggacgg
     4381 tgcgggccgg ctgaacgggg tgcggctgac gcaccgcaac ctcctcgcgg gcgccgccca
     4441 gaccgccctc gcccaccgcc tgggcccctc ctccgtcgtc ctcaaccacc tgccgcagta
     4501 ccacgccgtg cacctcaact cggccgtgca cgccggggcc cggcaggtgc tgtgccccgg
     4561 cccggatccc ttcggggcgc tggaagcagc cgcgcgggcc ggggccaccc acttctacgc
     4621 cccgcccgcc cggctgcacc gcctcgccgg cgacacccgg ctgggcggcg ccggtgcccg
     4681 gacgggcgcc cgccggctga gcgccctgca cgtcagcggc ggcgcgctgg agcccgaccg
     4741 cgcccgccgg ctgcgcgacg cgctgcgcgt gccggtcctg cagggctacg gcctcaccga
     4801 ggtgtgcacc ctctcccatc accagccgcc cggctcgcgg cccggtctgg gcgcggtcgg
     4861 ggtgccgctg ccgggcaccg agtgccgggt cgtcctgccg ggcggcacgc tgcccgcgcc
     4921 ggtgtggtcg accggcgagg tgcagatccg cgggccccag ctgagcccca ccgccccggc
     4981 cggcccggcc ggggcggtgc cggacgcgga cggctggctg tccaccggcg atacgggcta
     5041 tctcgacgcg gacggcggac tgcacctggt cgacgcgtcc ggggcggtgt tcgcctgcga
     5101 cgacgccctg gtcgccccgg ccgtggtgga acgggtcatc ggccaggacc cgcgggtggc
     5161 cgactgcatc gtcgcggact ggcccgaccc ggcacgcggc gccctggtct gggccggcgt
     5221 ggtcctgcgc gagaggcccc ccggcgacga ccgcggcctg ctcgatgtcc tcgactcggt
     5281 cgccgaacag gccaacgccc ggctcggccc cggcgagcag atccgccgcc tggaggccct
     5341 cgacgccgtc ccccgccggc cgggcggccg gcccgcccgc cgtgaactgc gccgccggct
     5401 gcacgccctg gccgccgtgg aggccgccgc gtgacccccc ggggggcgcg ggagtcagag
     5461 ggggtagcgg acgggtcgtg gcccgctgga gcgcaccgga cacggccgcg cccgccgcct
     5521 acggtgagca gggcgggaca tcccaggacc cggcaggaca tccaaggacc ggcaggacaa
     5581 cccaggaccg gcaggatatc cagggaccgg cgggacatcc cgggagacag ggaggagacc
     5641 gccatggacg agcggcacgc cacactccgc gtgctccccg caccggcccc cggccctgac
     5701 cccggccccg gtgaggcggc cggcccggtc ccggcccccc gcccgggcgc gccggccgcc
     5761 gtgcgcgtgc acgtgatcgg tgaggacccg ctcgcccgcc gcggcatcac cgctctcctc
     5821 gagggccacc ccggcatccg cgtcaccggc gagagcgaac cgggaccgcc gctgctgcgc
     5881 gcgctggccg cccggccccc gcacgtcctg gtcgcccacg gcgcgctggg cggcggacag
     5941 cttgccgcgc cggccttcgg cggcggggac ctgccgctgc tgaccctcgg cggcccgggc
     6001 cacaccgacg ccgcgggccg ggcggccggc ggccatctgc cggccaccgc caccgccggg
     6061 cagctggcct ccgcggtcgt cctggccgcc gccggataca ccctggtgca cggccccacc
     6121 ccgcccccgc ccggtcgccg gccggccgcc gggccgccgg cgcccatctc gccggtcagc
     6181 cccgaccggc tcaccgaccg cgagtgccag gtcctggacc tgctggcccg cggcctgtcc
     6241 aacggggaga tagcccgggc gctgaccctg tccgagcaca ccgtgaagac ccacgtgcag
     6301 aacctgctgc acaagctgcg gctgcgcaac cgggtccacg ccgcgatcta cgccttcgaa
     6361 tccggcctgc gcgccccggc cgcttccctg cgcccggccg ccgtcgcagc cgacgccccc
     6421 tccggctccg gctgaccgcc ccgcccaccg cagcagcgcc cgcctcccac gcgcgcccgt
     6481 ctcccgcccc gtacaccccg ccgggccggg gccagcaagc ccggccccca gagccttgtc
     6541 acggcggcgc agccgcaatc gcaggccacg ctgtttgggc aactggcacg cagcggcgcg
     6601 gcggaacgcc gttgagcggt agcggccgtg gagcaggctg ctgtgttcgt cgcctccggt
     6661 ccgtaggacg gctatgtggc cacatcgcct ggacgccgtc gttctcgagg acctgccccc
     6721 gggcgggctc gtcagagaac aggtcacccg aggacgggtg gcgtgtgctg gtcaccatcc
     6781 gccgcgctca cctggatacc gcgccggctt cccgctggag gcagcagccg tcatgatgca
     6841 catctgtccc agagggagcg gcagataccg cgtctgcgtg accgggggcg ggcagggcgg
     6901 ggataatcgg ccgcatggct tcacagtcct cacccgtctc cttgccgtcc gccgccgaag
     6961 ttctgcggga gcggtacgcg ggtcgcctgc ccgcctcgct cgacgagctt tccggacccg
     7021 cgcagggccg ggttgaactg ccgctgcacg tcgcctggtc cgggcttcgc gcctacgacc
     7081 tggaccggcc gcgccagcgc atgagcctgt accgcacggt ccttgccgag gggcagcgtg
     7141 acgacctgat caccctgctc gaccgggacc tgctggtcgc ccagtggccc gtgctgcgca
     7201 ccctggtcag caggcacatc cgcctggtgt gggaggacgc ttttcccgcg ctcgccaggc
     7261 ggacgccgac cgccgcgtga acctcagcga gctccaccgg cggctcttgg ccgatgtcct
     7321 cgcgatcggc acgccgtacc ccttgatcat cacgggtgga tacgcggtcc aggcccatgg
     7381 gctggtcgac cggctgagtc aggacctcga cgtcgccacc gagaatccgg cccccctgac
     7441 ggacatcgtc cacgctgtag agcacggtct ggtccaacgt ggctgggccg tcacggtagt
     7501 cagcgtggac ccgctctccg cacgtcttgt ggccgccgtc cccgcaaccg gcgaggactg
     7561 cgaagtggac atcctcaaag agaacctctg ggcaccgccc gtggaaacgg agtacggcct
     7621 ggtcctcgct cttcctgacg tcatcggcac caaggtccgc gccctggccg accggggcgc
     7681 ggtaagagat ctcatcgacg tgcacgccgc cgccgagcac cacaccacga acgacctcga
     7741 acggctcggc gagcggcacg gccgcgacga gttccgcctc caggacctcc acgaccgtct
     7801 cgccggcgcc gagtggtacg acgacgagga gttcgccgcc tacggactca ccgaggacga
     7861 gacctcacgt ctacgggcct gggcccagca ttgggcaagc gacctcaacc agcggctcgg
     7921 tgcagacgac cacgaggtct gatgctgcgg ctgctcgtgt gtgggccggt gcggctcgct
     7981 ttggtcccca tcagcggtgc gagccgggct gcggcccggt gggccggaac cagcccgatc
     8041 gcgcccatcg gctcacgcag cggctcggtc ggccggccgt gccgtcggta cctcttggac
     8101 gatggtcctg agcggatacg gcggcgtggc gcagccgaac cgcggccgcg caaggccact
     8161 acccccgctg cccggggctc acctcgttca cggcagccga atgccggccc cgccggccga
     8221 acgaggagcg aaatcaaggc gacttccgac acctccggca caggatcaac tattgcaacc
     8281 cgtagtcggc tgacggaact tgtgccagac cccccccagt atttacagac accctgccgc
     8341 gctgccgtcc tgatccgcag cacctgccgt cgggccggcg tcccgcacac cacccccggc
     8401 ccggcggcgg ggcacggggc acggggtagg ggggtgcaaa ggggcacggg gttacgtggg
     8461 ttacggggcg ggcggggcgc agcgtttggg ccagccgatg tcctcgtcgg acggtgcgtc
     8521 cggcgccggc ggggcggggt ggccggtgtc cgctgccggg gaggggccgc tgccgtgtcc
     8581 cgcggtggcc gtccacgccg cccggggtgg tgcgcacacc aatggcctca tcgtcgactc
     8641 ccgggcgttg acctgcacaa ggactccgcg cccggccggg tgcgccggcc gggtcctgcc
     8701 gagcgtgccc cgccgcgctg gaggaacgct ggaggagtcc acgagaggcg cgtgagagac
     8761 gcgtgagagc ggcacgagat tcccggcggg ggcctggcaa aggtttgccc gcgtgttgcc
     8821 cggcgcccta cgctcggggc ggctcccggc gaaactttct tgcccgctca ccccagggga
     8881 ttcggtcatg ctgcgacagc ccgcgttcgg acaccgcctg aaaaagctcc ggacggccca
     8941 ggggctgtcg cagacggcgc tggccggcga gggcatgtcc accggctatc tctcccgcct
     9001 ggaatcgggg gcgcgccagc ccaccgaccg ggccgtgggc tatctggcgg gccggctggg
     9061 cctggacgtc gccgacttcg aggagccggt caccggttcc ctggcgcacg cgctgacgct
     9121 ggcgtcctcc accggttccg cggacgccat cggggcgctg cgcgcggcgc tggccgccga
     9181 gggccacgag agcgcggtgc tgcgctggca ggcgctgtgg ctgctggccc gggccgcccg
     9241 gctgcagggc gaccacgccg ccgaacgcgc ggacctcgac cggctggtgg cgctcggcga
     9301 cgaggtggga tcggccgagc tgcgggtgcg cggcctgacc cggctggccc gctgcctgcg
     9361 ctcgctcggt gagatcaccc ccgccctgga cgcggccgtc gccgcccacc ggctcgccct
     9421 gggcgaggac ctgggcgtgg aggaccgggc cgccgcgctg ctggcgctgg tgtcggtgca
     9481 ggcggaggcc gggcaggtgc cggaggcgcg ggtgcacgcc gacgaactgg ccgcgctggt
     9541 cgccggccgc accgacgcgc tgtgggccga ggccatgtgg acggccgccg ccgtccgggt
     9601 gcgccagggc gaccacaccg gggcgcaggc ctttttggac gcggccctgg agcgtttcag
     9661 cagccaggag gacctggtgc tgtggctcag gctgcggctg gccgcgggcc ggctgcacct
     9721 gcagaccctg ccccccgacc ccgcgcgggc cgaggcgtgc gccgcccagg ccgaggccgc
     9781 cctcgccttc gtcggcacgc ccgccctgcg ccaggacctg accgcgctga aggccgatct
     9841 ggcgttcgcc accggccgct acgacgatgc ccgcgccctg ctgggcgacc tggccgggga
     9901 cgagccgagg atgacctacc gcgaccgggt gcggctggag atcctgcgcc agcagctgct
     9961 gatcctgggc ggcgacgcct ccggcgtgga ggggctgcgc accctggcgc agcaggccca
    10021 ggcggacgcc aacatcgacc tcgcggcgga gatctggcgg accctcgcgg acgccctcgc
    10081 ccagtcccgg cccgccccgg ccgaaccggc gtgacccgcc gcccgcgccc ggccagacca
    10141 ctgcgggagg aaagggacgg ggagggggaa ggggaagggg cggggcaggg aagggcgggg
    10201 aaggcggggg cgggggagtg ggggaattcg ggcgggcggg cggcgcgctg attcccgccg
    10261 gccgcggggg agtgcggtgc ggaatgcgta tgtcttttac cggatttctc gagggcgcct
    10321 cgcattccgg tggacgcggc gcaatgcgcc ttgacgcgcg gtgcggacct tcgtgaatct
    10381 cagtacggta ttggccgctc acgcccgaag ggacaccacc gtggtcagca agaagaagaa
    10441 tcccgcagga aacgagccgg agctcagccc cgcattcggc agtgagatca ccgacggccc
    10501 ggacgaggac accgagatgt ccgtcctggg cagcatcgcc ctgcagtagg ggccgccgcg
    10561 gacgggaagc gggaggcggg aggcgggaag ggggtggggc aggagacccg cgggtttccc
    10621 ttccccaccc ccttcccgtc tccgcggcgg ccgcctcccg cggtgtcagg acgccacgag
    10681 tgccacgcac atcgcgccca gcgccaccgc ctgcagcacg acccgggcgt tgatgacgct
    10741 gtcccaggtg cgctgcaggc cccgcgcgtt cggcgcggtg cggcagtcga gggccgcgtc
    10801 ggtcagctcc ttgttcaccg gcgcgctcac cttgttgtag acggccagcc acaccaccag
    10861 ggccgccgcc gcgacggccg ccgcgacggc cgccgtcacg cggccgccga acccggccgc
    10921 gacggccgtg gccaccgtgg cgagcaggcc gaagacgccc gggacgggca tccggcggtc
    10981 cccgaaacgg tggatctgcc ccatggtgct ggtcagcacc gcgtcgtcga cgtgcgcgag
    11041 ggccggccgc tggacgatcg cggagaagac gtcggtgccg tagaccaccg cgttggccat
    11101 cgtggccacc acggccaggg tctgtacgag ggtttccatc acaaccaccc ttgtccgtct
    11161 gccggttgcc acatggcctg ccgccacgtg gatttatcaa cgctagatgt cctgccgaca
    11221 ctatcaagtt cagtgcttcg aatgctagcg ttgacaactc cagtggtccg caggggattc
    11281 cgcaaggacg agggagcacc ccgggccgca gcggagtgcc gtcccctccc cgcggggaca
    11341 tccgcccgga cagccacgag gagacagacc catggccctt ggacgtgccc gtcgcgtact
    11401 catcgccggc ggagggatcg gcggcctggc cgcggccctc gcgctccagc gcgccggtct
    11461 tgagcccgtc gtcttcgaac gggccgaggc actgcgcgac ggcggcgcgg gcctgcacat
    11521 ctggaccaac ggcgtgctcg cgctggactg cctgggcgtg gccggacagg tcctgcgcac
    11581 ggccccggcc cagcaggtcg cgcacttcag cacccaccgc ggcgaggtgc tgggcgcctg
    11641 gccggtcggc gacttcgtcg agcgctacgg cgcacccacc atcgccgtcg agcgctccgt
    11701 cctgcacagt gtgctgcgcg aggccctgca cggctccccg gtgcgcaccg gggcccacgt
    11761 gaccggcttc gagcaggacg aggacggggt caccgtacgg ttcgcggacg gcggcagcga
    11821 acggggcgac ctgctgatcg gcgccgacgg catccacggc acggtccgcg acgccctctt
    11881 cggccccgcc cgcaaccgct acagcggcta catcgcctgg cgcggccgtt cccccctgca
    11941 gcacccggac atcccgccgg gcaccttcaa cgcgatgttc gggcccggca cccgcttcac
    12001 ctactacgac gtcgcacccg gcctggtcca ctggatgagc gtggccaacg ggcccgcggg
    12061 cggccgggac gcgcccggcg tgcgggagat gctgctgcgc cgccaccgcg gctggggcgg
    12121 cccggtggcc gacatcctcg ccgccacccc ggaggagggc atcatccgcg gcgacgtcga
    12181 gggccgcagc cccgaacgcc ggtggggcca gggccgcgtc accctgctcg gcgacgccgc
    12241 gcaccccatc accttcaaca tcggccaggg cgcctgccag gccctggagg acgccctggt
    12301 cctcgccgag cacctggagc acgccgacga ccccatcgcc gcgctgcgcc gctacgagcg
    12361 cgaacgccgc gcccgtaccg cgccgttgca gcgcatcgcc tggcggatcg ggcggatggg
    12421 cgcggtgcag aatccgctgc tgatccgggc gcgcgaggcg ttcatgcgca agaactggaa
    12481 cacgaaggcg ttcgccgccg cggagaaggg ccaggtcgcc tacggcaccc gctgggcccc
    12541 ggcccgccgc ccggcccccg ccccggccgc caccgtggac tgacgcccgc cctcgcggcc
    12601 ccggcccccg ccccaaaacc ccccgttcca ggcccggttg cgggccccgt ctccggctgt
    12661 cgcgcccgtg ggcccggggc cccgcggacg gaccaggccc acggcccctg aaccacggac
    12721 tgcggggcta cgggaccggg cccgggcccg tagcccggtc ccggaccgga gatccagccc
    12781 cggctgtcct gcccgcggcc cccggctcac gggccacgga cggtcccggg tcccgggtcc
    12841 cgggtcccgg gtcccggccc cgtacccgcc gcctcgggct cacgagccac ggctcacgag
    12901 ccacgggtca cgaggacgga ccgcgggcct gggtcctcgg ccctgggctt ggcgtcccgg
    12961 ccgcaccccg cggctccggc ccggattcgg cccctcgggt ttcggtccgg cccggtccag
    13021 cccggcgccg taccgtccca ccggtcccgc ccgcccggcg ggcgtcagcc gggcgccggc
    13081 cgccgctgca gggcgcccgg ctgccgtgcc ccggcccgcg ctgccggata cagcccgtcc
    13141 cagagcgggt cctcgggcgg aaaccccagg cagaccagga cgttgaccag catcccgtag
    13201 gccatgaacg tggtggtctg gccggtgtcc gcgccgagcg gccgatggac ggtgtcccac
    13261 agccgccgcc actcggcccg caccgcctcc ccgaacgccg cgtcaccgtc cgcctcgccc
    13321 gccgccaccg cgacgtacac ctgcatctgc atcagcagcc gctccggctc cttgacgatg
    13381 acgcgggtgt acgcgttggc catggcgcgc agcgcctcct cgcccgccag gccctcggtg
    13441 gcctcggtga acagccgggc ggtgtcggcc aggcagcacc gcgccgccgc gaggaagagc
    13501 gcccgcttgc ccgcgaagag ccggaagagg tacggctgcg acacccccgc acgccgggcg
    13561 atggcctcgg tggacgtgcc gtcgtacccg ccccgggcga attcgctcac ggccgcgcgg
    13621 atgacgctcc ggcgccgctc gtctgcactc atcctcacca tgccagcacg ttagttgctg
    13681 attgccgggc gccgtagtgc cggtccagac gcattcaagg aatgcgccag agccccgtgg
    13741 cagattcaca gaatcgagca ccgctcgccg accgctcgat gacctttctc cggctctgaa
    13801 aacagctctc ccggaccgct ctcccggacc gttcttccag gtcttcggac agctcttccg
    13861 gcagttcttc cggcagtttt tccgacggtt cttccgacaa ctcagtgagg caggaacggg
    13921 gatgatcgac aatctcttca cgatgtttcc cgggcagggc tcgcagcgcg cgggcatggc
    13981 cgggcatctg ctgcgtgaac acccccgcac cgccggacgc gtcctggccc gcgccgagga
    14041 ggcgaccggc ctgccgctga ccgcgctgtg cagcaccgcg ccggaggagg agctggcccc
    14101 gaccgagatc gcccagcccg ccatcgtcgc caccagcctc gcggtccttg aggtactgcg
    14161 cgatcaggcg ggtttcgtgc ccgccgtggt ggccgggcac agcctggggg agtaccccgc
    14221 gctggtggcc gccggggtgc tggaggccga ggcggcgctg cggctggtgc gccgccgggg
    14281 cgagctgatg gcgggggtct cccgacaggt cggcggcgcg atgacggccg tactgggcct
    14341 tgccgccgcc cggatcgagg agatctgcgc ggactgcgcc cccctgggcg tggtggagat
    14401 cgccaactac aacgagccgg gccagaccgt gatctccggg cagcgccccg cggtcgagga
    14461 ggccgcccgc cgggcgctgg ccgcgggcgc cgagcgggcg gtggcgctga aggtctcggc
    14521 gcccttccac tgctcgctga tgcgggcgat cgaggacgag ttcgccgccg aactggagcg
    14581 cgtgcgcttc agcgcgcccc ggctgcccgt gatcagctcg gtgaccggca ccctggtgcg
    14641 cgacggcggc cacgcccgcg atctgctgcg ccgtcagctg gccgggccgg tgcggtgggt
    14701 ggacgtgctg ggcgccgcgg ccgcgcacgc cgtggacggc tgcctggagg tcggccccgg
    14761 ccgggtgctc agcggcttcg ccaaccgcac cggcgtccac tccgtggtgc gcagcaccca
    14821 cgacgcgcgc cggatctccg cactgctgcg cgagctcggg caggagcccg cccctggcgc
    14881 cgccgcctga cccggcgcgc ggaccggccc ccggcccgca cccaccgccc gctccctccg
    14941 cctctctacc tccacctctt cccttctcct cctctttcct ctcctccttc tctttctcct
    15001 tctcttcttt tcctctcccg tccgtccggt gcgggccccc gggccggtac cggcggaacg
    15061 acccatccga aaggcagcca acggtgtccg aaaccctgac ccccacctcg accgactact
    15121 tctccgcggt ccaggccgcc atcgccgacg ccctgggcat cgacgaggcc gaggccgtgc
    15181 ccgaggcgac cctgctcggc cagctgggtg ccgagtcgat cgacctgctc gacatcctct
    15241 tccgtatcga gcgcgccacc aaggtgaaga tcaccgtggc cgacatcgcc gccctgctgc
    15301 agggcggcat ccccgacgag gagttcggcg acgagaacga ggtcgtcaac gacaccggcc
    15361 tcacccacct ggagaaggtc ctgccgcagt tcgaccgcag ccagctcagc gagccgctga
    15421 ccgccgaggg cgtgctgggc ctgttcaccg tgcagaacct caccgacctg ctgaccgagc
    15481 gggccgcggc ccagcacgcc gcctgaaccc cgacccctcc cctccggggg ccggtggcgg
    15541 tgcgggccaa cggcgtcccg cacccccgcc gcccctcccg cccgcgcggg ccccggccgg
    15601 ccaccgcccc ctcgtagcag aaacgggaag agacagatga agctgaagga ccgcaccgcc
    15661 ctggtcaccg gtgcctcacg cggcatcggc cgggccatcg ccctggccct ggccgaacag
    15721 ggggcggccg tcgccgtcaa ctaccgctcc cgccaggagg acgccgccgc ggtcgtcaag
    15781 gagatcgaga cggcgggcgg ccgggccgcg gccgtcggcg ccgacgtcgc cgacccgcag
    15841 caggccgccc gcctggtaca ggaggccacc cgcctcctgg gccccctcga catcctcgtc
    15901 aacaacgcgg gcaccagcga cgacggcctc atctacgacg cgccgccgga cgcctggctg
    15961 aacgtcatga agaccaactt cggcggcgcc tggcactgca cccacgccgt cctggaacag
    16021 ttcatggccc gcggcgacgc caccatcgtc aacatctcct ccgcgatggg cgaacgcggc
    16081 tggatcggcc aggccaacta ctcggcctcc aagggcgcgc tgaactcctt cacccgctgc
    16141 gccgccgtcg aactcgcccg cttcggcata cgggtcaacg cggtcctggc cgggttcacc
    16201 ccgaccgaac tcgtggacgg cgtgctgcag cgcgacggcg gcaagagcat caagcggcag
    16261 atcccgctgc gccggttcgc caccgccgat caggtcgccg cggccgcggt gttcctggcc
    16321 ggccccgact ccggctacac caccggcgaa ctgctctgcg tggacggcgg gttctccgcc
    16381 cagctgggca tcggccgccc gtaacggacg cgtgagggaa cggaagaaga gacgacgatg
    16441 cgattccatc tgatcgaccg gatcgagacc tgcgcgcccc gcgagcacat caccgcgcgc
    16501 aaggtcacct ccgccgagga gacctactgg caggacaccg gcgacggacc cgcgctgccc
    16561 ttcgggctgg ccctggaggc cctgtgccag tccgccacct ggctgatcat gctctccacc
    16621 gaccaccggc tgcgcgccgc gctgctggcg gtcggcgagg ccaccgcgca ccgcccggtg
    16681 cgccccggcg aggtgctgcg catgcacgcc accgtcgagt cgatgaccga ggaggccgcc
    16741 ctgctggacg gcaccgtcac cgtggacggc gagaacgtcc tcgaggcgag cggcatcctg
    16801 tgcgcgctca tcgacgccga acgcctcgac gacccggccg ccacccggcg catggcgcac
    16861 cagctgcagg gcggggggcc ggtgggatga cccgagtagc catcaccggc gtcggcgcgg
    16921 tcaccccgct gggcaacgac gccggcacca cctggcaggg cctggccgcc ggccgcagcg
    16981 gcgtcgggcc gctgaccacc ttcgacgcgg ccggcttccc ggtgcgtatc gccgcccagg
    17041 tcaaggactt cgacccggcc gcggcgatcc cggcccgcat cgggcgcaaa cacctctccc
    17101 gggtgggcct gttcggtgtc gcggccgcct gggaggcgct gcgctccgcg cgggccgagg
    17161 acctggggga ggaggtgtac gaccccggcg agcgcggggt ggcgatgggc gcgagtgtcg
    17221 gccgccccga gctgcaggcc ctcctggacg tcggccacct gcgcgccacc accggccgcg
    17281 cggacgcgtt cttgtgccac ccgccggccg tcaccctcac cgacgaccag aacgtgccgc
    17341 tcagcgcgat ggcccggatg atgtccgcga ccgggccgat gatcgggatc tccaccgcct
    17401 gctccggctc cgggcacgcc atcggggagg cctaccgcgc catccaggag ggcgatgccc
    17461 ggctgatggt cgccggcggc tacgactccc tgaccacctg gctcgacctg ctgggcttca
    17521 gcctgctggg cgcgctgacc gaccgtcaca acgacgatcc cgagcacgcc tcgcggccct
    17581 tcgacgccga ccgctccggc ttcgtgatcg gcgagggcgc cgccgccgtc gtcctcgagg
    17641 acctcgacgc cgcccgcgag cgcggcgcgc ccgttctggg cgaggtcctc ggctacggct
    17701 ctaccctcaa cgcctggcgc atcaccgact ccccgccgga cggctccggc gccgtccagg
    17761 ccatggaggc ggcgatcggc gaatccgggc tgggcaccgc cggcatcgac tacgtcgtcg
    17821 cgcacggcac cagtacccac ggcaacgacc agtccgagac ggtcgccatc aagaaggtct
    17881 tcgccgacga cgcccgccgt ctggtggtca gcgcccccaa gtcgatggcc ggccacctca
    17941 cctccgccag cctgggcctg ggcgtgctgg ccgcgctcgg cgcgatccgc cactccctgg
    18001 tcccgcccac cgtcaacctc gagcggcccg accgcggcct ggacctcgac tacgtgccgc
    18061 acaccgcccg cccgatgccg gtggcggcgg ccctgatcaa cgcgttcgcg ttcggcggca
    18121 gcaacaccag cctcgtcgtc ggcgccccgc gggaggacac atgaccacca ccgtccccac
    18181 cgcgggaccc acccccaacc ctgtttccgg cgcgggctcc acgacggtca cgaccggccc
    18241 cgttgccggc gcggaatccg cggccgccgc cgtgcccggc ggcgggccgg gcggcttcga
    18301 ccggctgctg gaggccgtcg tcggcgagcg ggcggcggcc gtgcgcaacg tgcccgccac
    18361 cctgacctgc ttcaccgacc acttcccgcg ccaccccgtc ctgcccggcg tgctgctgct
    18421 ggagagcatg gccgcgctcg cccgtaccgc cgcgggcccc ggcacctggc gcctggccgc
    18481 cgtgcgcggc gtgcgcttca agcacttcgt cggccccggc gaccaggtcc acctcaccgt
    18541 cgaggtgagc gctcacggcc cgcaccgcac cgagtgccgg gccaccgccc gggccggcgg
    18601 ccgggtggtc gccaccgccc gcgtcctggc cctggtcagc gacgagacga cccgggaggg
    18661 cacagcatga gcgagcagcg ccgccgcgtg atggtcaccg gcatcggcct gatgaccgcg
    18721 atcggccaga gcgccgccga gacctggcac agcctgctgg agggccgctg cggcatcgga
    18781 ccgctgcgcg cctacgaccc cgccccgctg cgcaccggca tcggcgccga gatcccctcc
    18841 ttcacccccg cccagtgggc ctcccgccgc accctgcgca tgctgtgccg cggcgaccag
    18901 ctcgccctgg ccggcgccac cctcgccctg caagatgcgg gcctggacga cgggagcgac
    18961 ctgggccacc gcgcgggcct gttcctgggc agcaacaagg aaatgccccg catggacgag
    19021 ctcatcgccc agctgcaggc cgtccgcgcc gacgacggca cccccgacct gcaccggctg
    19081 gggcagagcg cctcctcggt gatcgccccg ctgttcttcg tcgagggact gcagcccgcc
    19141 gccgccttcc acatctccga gaagtacggc atccgcggcg ccaacgccta cttcgccggc
    19201 accgccgact ccggcgcgat ggcgatcggc cggggcatgc gcaccgtacg ccgcggcgag
    19261 gccgacctcg tgctcgcggg cggctacgac gacgccaccg gctggtgggc gatgtccaag
    19321 atggacggcc tgggcgtcct gagcacccgc accgacctgg gcaccgaggc cttcaggccc
    19381 ttcgaccgcg accgctccgg ctcggtcttc ggcgagggcg ccgccctcct ggtcctggag
    19441 gaacgcgaac acgccctggc ccgcggcgcc cgctgctacg ccgagatcac cggcttcggc
    19501 gccggcaacg actgcgtccg cccgcccagc ccccagcccc gcgcccgcgg cctggcccgc
    19561 gccatcggcc gcgccctcgc cgatgccgca cggcccttcc ccgacggcag ctacatcgcc
    19621 gcgcacggct gcgccaccca gcagggcgac gccagcgaga ccgtcgccct gcacgacgcc
    19681 ctcggcacgg ccgccaagtc cgcccagatc agcagcgtca aaccgcagac cggacacctc
    19741 gtcggcggcg ccggcgcact gaacgcggcc gtcgccgccc tcgccctgga cagcggcacc
    19801 gtgcccgcca ccctcaacct gcaccacccc gccgccgagt gcgacctcga ctacgtcccc
    19861 ctcacccccc gccacacccg gcccgacagc gccctggccc tggcccgcgg cctggagggc
    19921 caggccgtcg ccgtcgccct gggacggacc tcatgaccga cacacccgca acacccgcca
    19981 tatccgaaag gagtgcggcc atgaccgacg tccacgaccg cgccgtacgg ccggacaccg
    20041 cggcccggcc ccggaccgtg gtggtctgcg gtgtcggcgc cgtgaccgcc cagggcgagg
    20101 gcgccgccgc gctgtgggag ggcatccggg ccgggcattc ggccatcggc ccggtcaccg
    20161 gcatgccgat ggacggctac ggcacggcca tcggcggcga agtgcccccg ctgtcccggc
    20221 ccgcctacga ctacctggcc gccttcggcg gcagcgagcg ggaaccggcc gtcgacttcg
    20281 ccctgaccgc cgccgccgaa gccctccagc aggcgggcct tgcgggactg cccgccgaac
    20341 gctggggggt ggcgttcggc tcctgcaacg gcggcctgcg cagcgccgag aaactcgccc
    20401 gccgcagccg cgagggcacc accctgcccg acgacgccct gcactacctg ctggtcccgc
    20461 cgcaggccat cgccgaggca ctcagcgccg ccttcgctct caaggggccg gccctgtccg
    20521 tcaacaccgc ctgcgcctcg ggcgcgcacg ccatcgcgca cgccgccgag gcgatcgccg
    20581 cgggccgcgc ggacgcgatg ctcgccggcg gcagcgacgc cttcaccgag accgcgttcg
    20641 ccggcttcac cagcctccag tcgctgtccg ccaaacccgc cgccccctac tccaaggacc
    20701 gcgacgggct gtccctgggc gagggcgcgg gcatgctggt gctggccgag gagtcggtgg
    20761 cccgcgccgc gggcgccccc gtcctggcgg aggtcctcgg ctacggcctg tccgccgacg
    20821 gctaccacgc caccgccccg caccccgagg gcgagggcgc cgcccgcgcc atccgcggcg
    20881 ccctgaaggc cgccggcatc accccggggg acgtcggcta catcaacggc cacggcaccg
    20941 gcacccccaa gaacgactcc gccgagtcca acgcggtgcg cgccgcgttc ggcgaggccg
    21001 cccagaaaac cgccctgagc agctccaagt cgatgatcgg ccacctgctg ggcgcggccg
    21061 gcgcggtcga ggccatcgtc accgtcaagg ccctggtcga acagatcgcc ccgccgaccg
    21121 ccaacttcac cggcaccgac cccaagtgcg gcctggacgc ggtccccgac accggccgcg
    21181 aactggccat gaacgccgcc ctgtccaaca acttcgcctt cgccggcgcg aatgcctgcg
    21241 tcgccttcgg ctggccctcc ggacggcgct tcaccgtccc cgccccgccc gccgccgaga
    21301 aggtcgtcat caccgggggc gccgccctca cccccgccgg cgaaggcctc gaggcgctgt
    21361 gggaggcctg gcggcagggg cggcggctgg gcgccgacga ggacggcctg cgcgtggccc
    21421 gcgccgtctt cgaccccgcc gcccacatcg gcgcccgcga ccggcgccgc atggaccgcc
    21481 tctcccagct cgccgtcgcc tcctgccgcg ccgccctcgc ccacgccggc ctgaaggccg
    21541 acgagcacac cggggtcgtc ctgggcaccg gactgggccc gatgcgcagc atcgaggact
    21601 tcctgctgcc ggtgctgggc ggctgccccg cccacggcag ccccgccgtc ttccccaaca
    21661 ccgtcttcaa cgccgccgcc ggccaggtcg ccatgcacgt cggcgccaag ggccccacct
    21721 ccaccgtcac caccggacat gccgccggcg cctccgccct gaccgtcgcc cacgacctgc
    21781 tgctgcagca ccgcgccgag gcggtgctgt gcccggcggt cgaggacctc tccccgggcg
    21841 tgctggccgc ctaccgccag ctgccgctgt tcggcgacgc cggctacacc ctggccgagg
    21901 ccggcatcgc cctcgtcctg gaacgcgaat ccagcgcccg cgcccgcggc gcccgcatcc
    21961 tggccgagtt cgccggccac gccgccgccg gcgacgcggc cggcatcggc cgctggaatg
    22021 cccagggcga gggcgtcgag cgcgccatgc gcgccgccct cgcccacgcc ggcctcaccc
    22081 ccggcgagct gaccggcatc tgggccaacg ccgccggcct cacccgcgcc gacacccccg
    22141 aggccctcgc caccggccgg ctggccgccg aggcccgctg cccggtgcac acccccaaac
    22201 agaccctggg cgaaccggtc ggcgcgggcg cccagctggc cgccctcctc gccctcaccg
    22261 cctggaccac cccggcaagc ggggcggcgg cggggccggt gctcatcaac agctcctcgc
    22321 tcggcggcac ccacatcagc ctcgtcctgc gtcccgcaac ggagaactga ccatgcccca
    22381 cacctccacc gccccgcccg ccgaaccccg cgcccgccat gtctcggtcc tggccaccgg
    22441 cgcccacctg ccgggcgagg ccctcgacaa cgacgccctg gcccgcttct gcggcccgct
    22501 gcccgccgac gtcctggacg gcatccaggt caagcgccgg cactggatgg tcgacccggc
    22561 caccggcacc cacaccacca gcacctcgca gatggccacc gccgccgccc gccaggccct
    22621 cgagcgggcc ggcgtccagg cggacgagat cgacctgatc gtcctgtcca ccgccagccc
    22681 cgactacctc ctgcccgtcg ccgccaccta cgtccagcag cagctcggcc tggaggactg
    22741 cgcggtcatc gaggtccgcg ccggctgcgt gggcgccgtc caggcccacg acatcgcccg
    22801 ccgcctgctc gccgacggca cctacaccac cgccctggtc atcggcgccg aggccgtctc
    22861 cccgctgctg gcccccgtct ttttgggccg cgaccccgaa cgcgtacgga tgcgcgaccg
    22921 gctgaccgtc tacaccttcg gcgacggcgc cggcgccctg gtgctgcgcg ccggcgagga
    22981 gggctccgcc cacggccgcc gccgccccgt cttcgccacc cgctccctgg gcggcgcccg
    23041 caaacccggc atgctcatcg tcggcggcgg caccgacgcc cccctcgccg aacagcagcg
    23101 ccgcccccgc ctgatggaca tccgcctcga catccccggc accgcccagt tcggcccccg
    23161 cgtcttcgtc gagggcatcc acgacctgct cacccgctcc cgcctggccc tggccgacct
    23221 cgacgcgtgc gtgctgcccg agggcaacgc cgagtacttc gccagcgagt acgccgccgc
    23281 cgggctgtcg gccgccgacc aggccgccct gagcaagacc atcgtggaga acctcaccga
    23341 cgtcggcgcc accggctccg ccgccgtccc cctcgccctc gacgccggct ggcgcgaggg
    23401 ccgcatccgc cccggcgaca cggtcctgct gctggccatc gaggccagcc gctacctgta
    23461 cgcgggcctc accctcacct gggacgcccc cttccccggc cactgaccgc cccgcgcccc
    23521 cgaccccgcc cctgtgacct gcgcccccgc acccgcggga cgccgagacc gaaggacgag
    23581 agaacgtgtc gatacaagag acggagcgca ccgcccgcag cgtggaggaa cgcaacaaga
    23641 agaccatccg ccgggtcttc gacgccttcg tcaaccaggg cgacttctcc gtcgtcgacg
    23701 agatctacag ccccgacatg atcgaccacc agccgctgcc cggcgccccc gaaggcctcg
    23761 aaggcgtccg ctacaccatc gccggcctgc gcgagggctt ccccgacctg cacgtgacca
    23821 tcgaggacat gagcgcccac ggcgaccacg tcgtcatcca caacacctgg cgcggcaccc
    23881 acctcggcga cttcctcggc gcgccgccca ccggacaggc catcgagttc accggcgtcg
    23941 tggtgtggcg gctgctggcc gacggcctga tcgccgaacg ctggggcatc ggcgtggagt
    24001 ccaacatgct ggccgtgctc ggcctgcgcc ggctcgcccc cgccgcccgc aacggcgccc
    24061 gcgccgcggc ccgccgcacc gtcacgagcg ccggcgccct gctgccgctg ccgcccggcg
    24121 ccgccggcgc ctggcacgcc cttcaggccg agctcgccgg agcacggctg cgcgcctacg
    24181 aggcctcccg gcgccgcgcg ggcatcctcc aggagtcctt cgccctccag cccctgggcg
    24241 gccaggacgt gctggtccac cggatcgagg cccgcgaccc gcagggcgcc gcccgccggc
    24301 tggcggcctc cgccgacccc ttcgactcct ggctgcgcca ggaagcggcc gcggtgctgg
    24361 gcaccgaccc gtggacccac ctggccgcca acgccacccc ggcgggccac acctggatgc
    24421 ccgtcaccag cgaactgacc accgccgact gaccaccggc cgaccgccgt ccgagcaccg
    24481 ggggaccggc accccaccac ttctctagca aagacaccga cactgtcact gctagacggt
    24541 cactgctaga cgacaaccgc cccgtgcacg gctcaggaag gaaccgatga tgcggcaacg
    24601 aaaactcggc agccaggggc tggaggtctc cgagcaggga ctcggctgca tgggcatgac
    24661 cttcgcctac gggcccgccg acgaccagga agccctgcgc accgcgcacc gcgccctgga
    24721 actgggcgtg aacctcctgg acaccgcgga cttctacggc ccgcacagca acgaggagtt
    24781 cgtcgcccgc gtcatcgccg gccgccgcga cagcatcacc gtctcctcca aggtcggcaa
    24841 cgaggtcacc gccgacggca ccatcaccgg ccgcctcaac ggccgccccg actacatccg
    24901 cacctccatc gacgccaccc tgcgccggct gggcaccgac cgcctcgacc tgtactacct
    24961 gcaccgcgtc gaccccgccg tccccgtcga ggaatccacc ggcgcactcg ccgacctcgt
    25021 caccgccggc aaggtccgcc acctcggcat ctgcgaggcg tccgccgcca ccatccgccg
    25081 cgcccacgcc gtgcacccgc tcaccgccgt acagaccgag tactccctgt ccacccgcga
    25141 cgtcgaggcc aacggcgtcc ttgcggccgt ccgcgagctg ggcatcggct tcgtcggcta
    25201 cagcccgctg ggccgcggcc tgctcaccgg agccatccgc agcctcgacg ccctcgccga
    25261 acacgacttc cgccgcgtcg tgccccgctt ccagcagggc aacctcgaga ggaacctgca
    25321 cgtcgtggag cggctgcagg cgctggccgc cgccaaacag atcaccgccg gacagctcgc
    25381 gctggcctgg gtgctcgccc agggcgacga cgtcgtcgcc atccccggca ccaaacgcgt
    25441 cacctacctg gaggagaacc tcgccgcctc caccgtcgag ctgagcgcgg ccgatctcgc
    25501 cgccctcgac gagatcgccc cccacggctc cacggcgggc gaccgctacc ccgtcggtgc
    25561 catggccacc ctcgacggct gacccccgac cccggcccgc gggccttcga aggcgaagtg
    25621 agtgcgataa ccatggcgaa catcacgatc atcggcggcg gactggccgg cctgaccgcg
    25681 gcgatctccg ccgccgaaca gggcgcccgc gtcaccgtcc acgaggccca ctcccacacc
    25741 ggcggccgcg cccgctcggc cgccggcccc tacgtcacca acgacgggcc gcacaccttc
    25801 ttcgacaacg gcgacgcctg gcactggctg ctgcagcgcg gactggccgg ccgctacgtg
    25861 cggctgtcct tccacgagtg gacccggatg cgcttccgcc accagggccg gctgcggatg
    25921 accctgccgt ccggctacat gaagatgacc tggcgccacc gcggcatcga ggtccccgtc
    25981 gaccgctcct tccaggactg ggccagcgaa cgcttcgccc agcagaccgt gaacgaggcc
    26041 ctcggcttcc tcggcccgat cctcttcgac ggcgaccccg gacgcctgtc ggcagccttc
    26101 gtgtgggagc ggctgctgcg cgtgggcacc ccccgcttcc cgctgcccag ccgctacttc
    26161 atcggcggct ggggcgcgct gatcgagcgc atggaacgcg tcgcccgcgc ccgcggcgtg
    26221 gtcatcgaga ccggctcacg gctgagcgaa ctgcccgccg acggaccggt gatcgtggcg
    26281 acctcgctgg cctccgcgcg cagcctgctc agcgaccccg gccttgaatg gcccagcggc
    26341 accgccgccc tgctggacat ggccgtcacc cactccaaga aggacggcaa cgtctccttc
    26401 gacatggacg agggcggctt cacctcccag tactccgacc acgacccctc cctcgccccg
    26461 aagggccagg ccctgttcca gggacagatg ccgctgcggc ccggcgagtc gaaggccgac
    26521 gccctggccc ggctggagaa actcttcgac ctgaccaccc ccggctggcg cacccgcctg
    26581 ctgtggcgcc gcgaaggcgt ctcccgcggc cgcaccggcg ccctggacct gcccggcctc
    26641 agctggcggg ataggcccgc catcgaccgc ggggacggcg tgtacctggc cggcgacagc
    26701 gtcgccgccc ccggcatcct cgccgagacc tccatcaaca gcgccctgcg ggccgcccga
    26761 ctcgccgtgc acacccgccc ggcggcacac cgctccgcgg cgctcgggcg ttgagtcccc
    26821 cttcgcgtcc caccccaccc ctgttaggga gcgcagcact tgacgctccc ctccctgacg
    26881 ggaggggatt cttacggctc gcgccgtgag acttcctgtt tcatcgccga ctgcccgccc
    26941 ggagaactcc gttgaggtct tacaccagct ccgcaggctg cgaccgcccg tccggcggcc
    27001 agaaggttct tcgcagcgtt cacgtcccgg tcgtgggtcg cgccgcagtt gcacgtccac
    27061 gtgcggacgt tcagcggcat cttgtcctgc aaggtgccac aggcggagca cagcttggac
    27121 gaggggaacc accggtccac ggcgatcacc tcgcgcccgt accactgggc cttgtactcc
    27181 agcatgctcc ggaactcacg ccatgccgcg tccgagatga cccgggccag tttccggttc
    27241 ttgaccatgt tgcggacggt caggtcctcg atcacgagcg tttggttctc acgcacgaga
    27301 cgagtggtga tctggtgcag gctgtcacga cgtcggtcag cgatccgggc atggatacgg
    27361 gcgaccttgc gccgggcctt gacgccgttc gccgaaccct tctgcttctt cgccagccgg
    27421 cgctgcgcct tcgccagcgc ggcccggtcg cggcgttcat ggtgggggtt ggtgatcttc
    27481 tccccggtcg agagggtcag gaggtgatcc agcccggcgt caataccgac cgccgcgtcc
    27541 gtggcaggca gatgtctgat gccggggtcg tcgcacagca tcgagacgaa ccagcgtccc
    27601 gccgcatcct gggacacggt caccgtggac gggttcacac cctcggggag cggcctggac
    27661 cacacgatgc gcagaggctc gctcatcttc gcgagctgca gctcaccgtc ccggaaacgg
    27721 aacgcgctgt tggtgtactc ggcggacttc ctggacttct tccgcgactt gaaacgcggg
    27781 tacttggccc gtttgccgaa gaagttggcg aacgccgtct gaaggtgccg cagcgcctgc
    27841 tggagcggca ccgaggagac ctcgttgagg taggccagtt cctcggtctt cttccacgcc
    27901 gtcagcattg ccgacgtctg gttgtagttg acccgctcct gacgcgtcca cgcctcggtg
    27961 cgggcggcga gcgccatgtt gtagaccttc cgcacgcacc cgaaggtgcg cgacagctcc
    28021 gccgcctgcg catccgtcgg acagaagcgg tacttgaacg cccgcttcac gtgagtggtc
    28081 acagctccca aactatcgca tcaacttatg accatttgtg ggaaattggc cgcgaacgac
    28141 gatccgccct tgcggcggat cacccgtccc tgccctgttc cgcaggagtc cgcttcccct
    28201 ccgccctgaa agacggagca tccacggagg aatcccgatg agaatcaccc tgtccgagcg
    28261 cggcaccccg gactggcaga ccgccgcgga ccttgcccgg ctggtgttcg ccaagcagta
    28321 ccaggcgagc atctcgcccg acccggacgg cttcctcgcc ttcttcgaga ccgccgccga
    28381 cggccaggag gaagtcctcg cctgcgcggg cctgtccttc cccgaggaag agagcatcct
    28441 gctcgagcgc tacctcgacg cccccgtcga agacgtcatc acccgggccg tgggcgcccc
    28501 cgtcaaacgc tcccaggtcc tgcagatcgg ctccatcgcc tcggtacggg ccgccgccgg
    28561 cgccgagatc atcaaggcga tcccgctgat catggcctgc ctgggccgcc cgtacgcggt
    28621 gatgaccatg accggccggc tcgccgccct catgcagcgc ctgggctgcg tcttccaccc
    28681 cctggccgac gccagcgcgg aacgcctgcc cgaaggcgaa cgggccgcgt ggggctccta
    28741 ctacgacacc cggcccgtcg tcggctacgc cgaggccgcc gagcagtcca ccctgctgct
    28801 ggccgccatc ggccgctact gcttcacctc ggtcgacatg cggctgctga gcaaccgccc
    28861 gcagcagggg gtgctcaccc gtgccgcctg acacccccac ccgtctttcc ctcgcccagg
    28921 ggctcctgga gcgggccggc agcgacgccg tcatggtccg cgtgctggca gccgacggct
    28981 cggcgcccgc cgcctggagc taccgcgacc tgaccggcgc cgccctcacc ctggccgccc
    29041 ggctccagga acaggcccag gcgctgggcc ggccggcacg ggtggggctg ctcgcggaga
    29101 actcgcccga atgggtcgcc gccgacctgg ccgccctgtt cgccggcgcc gtcgagatcc
    29161 ccgtcccgac cgccttcacc gcccagcagg ccgcctccct cctgcagagc gccgacctgt
    29221 gcctcaccga cagcgcaggc gaagccgccc tggcccgctg gcgcaccagc accccccagc
    29281 ccgtcctccc cgacggctgc cccgccgttg ccctcgacct gcccgccctt gcccgcgcac
    29341 cccgccccgc cgcgcccccg cagatccccg cacacgacca gatcgtcaag gtcatccaca
    29401 cctccggcac cacctccgcc cccaaaggcg tccagatccg ccgccacggc ctggacgaac
    29461 tcctcacctc cctgcgcgcc cgcacccgcc cggagatctt cgagcgctac ctgtccatcg
    29521 tcccgctcag cctcctcatc gagcaggtcg ccggcctcta catgcccttc ctggcgggcg
    29581 gttcggtgtc cttcctgccg ccgggcaccg ccctggtcgg caccgccgcc gacgccgccc
    29641 cccgcatgct caccctgctg cgcgcggccc gccccaccgc cctggtcgtg ccgcccaccg
    29701 tcgccggcct cttcctcgcc ctgtgcgacc agcagcccgc cgagagcgtc accgagcgcc
    29761 accggcggat cttcggacac gacgggccgg tcttcatcgc ctgcggcggc gcccccgtcc
    29821 ccccggagat cctccagcgc ctcgacgcct acggactgac cgtccacgag ggctacggac
    29881 tgagcgagaa ctcctccgtg gtgtcctgga acttccccgg cgccgtccgc ttcggcaccg
    29941 tcggccgccc cctggaccac gtgcgggccg aactcgccga ggacggcgaa ctcctcatcc
    30001 gcagcacctc cctgttcgcc ggctacaccc gcgaggaccc ctccagcgtc gtcgtcgacg
    30061 accagggccg cctgcacacc ggcgacctcg ccgagatcga cgccgacggc tatctgcgga
    30121 tcaccggacg caagaagaac ctcgtcatca ccgcgggcgg ccgcaacgtg gcccccgaat
    30181 gggtcgaggc ccgctaccgc gaactcggct tcgtccgcga ggccgccgtc gtcgccgacg
    30241 gcctcgacca ggtccacggc ctgttcgtca tcgacgccgg cctcgacccc caggccgccc
    30301 gccgcgagat caccgacttc ggccggcaca aactctccgg catcgaacgc gccgccgtcg
    30361 tccacctcat gtccgaggac gaccccgcct acgccacctg cttcaccgtc accggacgcc
    30421 cccgccgcga cgtcgtgcgc gcgcacgtcc tcaagcagcc ccgcaccccg gccccccgcg
    30481 gcggcgagac caaggagaag gcttgacatc tcccccagct gaagcagggg gattcttccc
    30541 tcgcgggttg agctttctgc ttctcagaca gcagctgccc cgaatcaacg gcgggggacg
    30601 ttggtacgcc cagcagtctt acgccagctc cacagacctg acatcccgcc agcccggcgg
    30661 taggcccggc cagcttggtt atcaccggcc gagcgtggca acgctactgc atccgcgggc
    30721 agttgctggt gaacgacgat ccgccctggc ggcgaatcgt cttcccttgc cctgctccgc
    30781 aggagtccgt ttcctcccca gcccgaaggc tggggtatcc acggaggaat ccagatgagc
    30841 acggctatga agaccacccc ctacggcacc ggcagcggcc tgctggtcga acccgcaggc
    30901 cccggcggcc tcgacggcgt cgaccccaag gaactgcgcg acctgctctc ccaggccggc
    30961 ttcctgctgc tgcgcggctt cggcgcggac atggacgcct tcaccgccct ggtgcagcac
    31021 acctccacct ccaccaccct cgaccccgcc cgcgacttct actccgaggt cgcccagaag
    31081 gtcgacgccg gcttcgacga ggtgggcctg cacaccgaga acggcaacag ccccttccgc
    31141 tcccacctcg cctggttctt ctgcgagaag gccgcctcct ccggctccca gaccaccgtc
    31201 tgcgacggct accgcgtctg ggacgccctc agcccccaga cccgtaccgc gttcgcggcc
    31261 caggacatcg tctacagccg ctacgtcgcc gagccgcagt ggcgggcgat ggcccaccac
    31321 ctgctgggcc gcaccaagcc cgccgacgag atcgacgtcg aagaactcct cgcgctggcc
    31381 ggccagttgc ccggcaccga gatcgtgccg caggacgacg gcggggtgcg ctactccttc
    31441 accacccccg cggccggcac caccgtgttc gggccgcgcc cctccttcgc caacagcatc
    31501 ctgggcccct ccttcaacta cgagaagccc accatcacct tcgccgacgg caccgccctg
    31561 tccccgcagc tgctggccga ggtcgaagag gtgaccgccc gcctcaccga gaacctcgac
    31621 tggcaggacg gcgacgccgc cgtcatcgac aacacccgcg tcatgcacgg ccggcgcgcc
    31681 atcaccgacc ccgaccgcac catctacaac gccctcagct acatcgaggc acccgccgcc
    31741 tgaccgggcc gcccctgccg cccccacccc gccggcgcaa gaagaagcag cagcaggagg
    31801 aggtaggggg caaggagggc gggaggcaga tccatccgag agggagccat gaccaccgac
    31861 cacaccgccg ccccccgcac gacggacacc gcacccgccg ccgcggatcc ccgccgctgg
    31921 cgcctgctcg tcttcgtcgc cctcgcccag ttcatggtgc tcctcgacac caccgtggtg
    31981 aacctcgccc tgcccgccat ccaggccgac ctcaaggccg gcgccaccgc cgtcgaatgg
    32041 gtgctgaccg cctacatcct gtgcttcggc ggcctcatgc tgctcggcgg ccgcaccgcc
    32101 gaccgctggg gcaggcgccg caccttcctg ctcggcgccc tgctgttcac cgccgcctcc
    32161 ctgctgtgcg gactcgccca gggcgccggc ctgctgatcg ccgcccgcgc cctgcagggc
    32221 tgcggcgccg ccttcctctc accggccgcg atgtccctgg tcaccaccac cttccccaag
    32281 ggccgcgaac gcaccaccgc gctcgccgtg tgggccgcgc tggccggcct cggcggcacc
    32341 ctcggcgtca tcgccggcgg cctgatcacc gacagcctca gctggcgctg gatcttctac
    32401 atcaacctgc ccttcgggat cgtcgccgtc gccggcgtcc tgctgctgtc ccggggccgc
    32461 cccgaaaccc gcatccgcgg ctcgcgcccc gacatcgccg gcgccgtcac cgtcaccgcg
    32521 ggcctggccg ccctcgtcta cgccatcgtc aacatccagg accacggcgc cgcctccacg
    32581 ccctacgtcc tggccccggc cgccgcctcc ctcgccctgc tggccgcgtt cgtcctgatc
    32641 gaacgccgca cccccgaccc gctgatgccg ctgcacctgt tcgccacccg ctccctggcc
    32701 accgcgggcc tgggccgcgt cctgaccagc ggcgtacagg cgtccgtgct cttcctgtgc
    32761 agctactacc tgcagcgcac cctgggctac tccaccctca agtccgggtt cgcgttcctg
    32821 ccgctgggcg tcgtcgccat cctcgtcacc gcccccgcca cccgcatcat gcacaaggcc
    32881 ggcccccgcc ccgtctacct cgccggcgcc gccggctccg tcctcggcct cctcctgctc
    32941 acccaggccc cgcagaacgg cacctacctg ctgcacctgc tgcccgccct gctcatcctc
    33001 ggcgcgtcca tgcagtgctg cggcatcccc gtcaacgtgc acggcgtctc cgacatcccc
    33061 gcccgccagc agggcatcgc ctccggcgtc ctggtcgccg ccttccaggt cggcgcctcc
    33121 ctcggggtcg ccaccgtcgc caccagcgcc ctgacccgca ccacccacga cctcacccac
    33181 cacaccgccc ccgccctggc ctggctggac ggcctccacc tcggcttctg gatcgccacc
    33241 ggcatcggcg tcctcaacct gctcaccgcc tacttcggac tgccccgcca ccgccgcgcc
    33301 cccgccccgg ccggcccccg caccgcctga ccacccccca accccccgac agacacggag
    33361 aggcccatgg cacgccccgg agacaccctc cacctcggca aggacaagct caccttcctg
    33421 accaccgccg ccgaaaccga cggcgccttc gtcgaagtcg aagtcgaata cgcccccgcc
    33481 gtcatcaaac cgccccagca ctaccacccc cgccagaccg aacacatgcg ccttcaaagc
    33541 ggccgcctcc acctccagct cgacggcgtc ctgcacgagt acgaacaagg cgccgacttc
    33601 tacatcccgc cgggcgccgt ccactccatg tggaaccccg gccccgaacc cacccgggtc
    33661 atctggcgca ccacccccgc ctaccggacc gaaaccgtct tcgagaccct ctggggcctg
    33721 accaacgaag gccggctgcg ccccgacggc accccccgcc tgcagatgcc gctgctcgcc
    33781 ctcgccttcc gcgacgagta ccgcgtcgtc accggccgcc cctaccccct cgacacggcc
    33841 ctgtgcctgc tgctctcccc gctctccctg gcctgcggct accgccccac ctaccgcccg
    33901 ccccagaaca ccgcgaccct ccagcccacc gcctgaacac accggcacag gcccggagtt
    33961 cgagccggac ccaagggcgc agcgagccgt gcgccctagc gtcggcccca accgaacacg
    34021 gccgatgcgt ggaggaatgg tcatggccac cgaagcacac gaattcaccc tgcccggcgc
    34081 ggatctcccg cagcccgacg ccgaactgcg caagaagcgc gaggcggtcg tcctgcagca
    34141 cacggtcgcc gagatcgcct gggacatcga cggcgtgctg gccaccttcc cgcgcggcgg
    34201 cgtctaccgc atccaggcct tcgaagaggg cccgctgatc ggcgaagaag ccatcaaaaa
    34261 gggctacttc gccgacctca aggccgcctt ccccgacctc gagcacgaac tgcaccacgt
    34321 gcaccacacg cccaccgccg tgatcctcga ggcacaggcc cgcggcaggc aggaggccga
    34381 ctggcgcggc atccccaacc gcggcaagtc catcgacgcc cccgtcgcgg tcttcttcca
    34441 cttcgacggc gacgtcctga tcgacgagac cctctacttc gacatcgcca ccttccagcg
    34501 ccagctcgcc tgaccctccc cccttctccg cgggcgcggc acggcggggc ccggacaccg
    34561 gccacaccgg tgtccgggcc ccgccgcgcc gcgcccgtgt gccgagcggg gctcgaggag
    34621 gacttgagtg cgcgtccgta gcgtcgacgg cgccgtaccg gcccgcgcgc gggcgcgggc
    34681 accagggcgc cgcgggccgg accggtcacg gcgatgagca tctcgcacga cccgcctcca
    34741 gaaaggatgc tcggatgagc accgtcaacc ccccatcccc gggcggtgaa accaggaggg
    34801 tggtcttctg ggccattctc accaccagcc tcgcctcgtt catggcggga ctggacaacc
    34861 tcgtcatcat caccgcgctg cccaccatcc gcgagaaact cggcggcagc ctcaccgacc
    34921 tggaatggac ggtcaacgcc tacaccctgt ccttcgcggt cctgatgatg ttcggcgccg
    34981 ccctcggcga ccgcttcggc cgccgcaagg tcttcagcct gggcctgctg ctgttcaccg
    35041 ccgcctccgc ggccgccgcc ctcgcgcccg gcatcaacga actcgtcgcc gcccgcgccg
    35101 tccagggcgt cggcgcggcc atcatcatgc cgctgtcggt gaccctgctg accgccgccg
    35161 tgcccgccga gaaacgcggc gcggccctgg gcatctgggg cgccgtcaac ggactgtcca
    35221 tcgccgccgg cccgctggtg ggcggcgcca tcgtcgagca cctgtcctgg cagtggatct
    35281 tctggctgaa cgtgccgatc ggcctggccc tggccccgct gtccttccgc aagctcgccg
    35341 aaagccgcat cgcccactcc cgcctggacg ccgtcggcac cgccctggcc agcctgggcc
    35401 tgttcggcat cgtgctgggc ctcatcaagg gccacggaga cggctggaca tccccccagg
    35461 tcctgggcgc actgatcggc ggcaccgccg tgatggccct gttcgtggtg tgggagaacc
    35521 gcaccgaaca cccgatggtg ccgatgcgca tgttccgcaa ccgcgccttc accgcgatca
    35581 acctggccgg cgccctcatg tcggtcggca tgttcggcgc gatcttcctg atgacccagt
    35641 tcctgcagaa catccagggc tacaccgcca tgcaggccgg cgtacggctg ctggcctgga
    35701 ccgccatgcc gatggtggtc gcccccatcg gcggcatggt ctccgaccgt atcggcggca
    35761 aacccgtggt caccctcggc ctcgccatga tgaccgccgg catggtctat tgggcgttcg
    35821 tcctcaagcc ggacgtctcc tacgccgccc agctgccctc cctgatgatc tgcggcgccg
    35881 gcatggccct gttctacgcc ccgctgatga acctcaccat gggctcggtc gccgaacacg
    35941 aacagggcat cgcctccggc gtcaccgccg ccacccgcga ggtcggcgcc gccctcggcg
    36001 tggccctgct cgcctccatc ttcagcgcca acggcggcta cgcctcaccg cgcaacttcg
    36061 tcgacggcct ggtgcccgcc atgtgggtgg gcgccaccgc ggtggccctt gccaccttcg
    36121 ccatgctgct ggccccctcc cgccggcgcg ccgccgcgag cgcccccgtc gcacaggccg
    36181 cccccgcgca ggagagtgca ccggcccccc tgcactgacc tggcaccggg gccggcgcca
    36241 ccccacgggt gacgccggcc ccggcgccgt cccacgaacc ggcaccccga cgccccgacg
    36301 aaccgaggac gcatggccat tgaggagatg aaggtccgcg acgccttccg gatcacaccg
    36361 tcgcaactgc cggacaaccg gggcctgttc ttcgaggcct ggcggctggg cggcctgacc
    36421 gcggcgagcg gccagccgtt caccgtccgg caggtcaact tctccgtctc ccggcgcaac
    36481 acactgcgcg gcatccacgg caccaccctg ccgccgggcc aggcgaaact ggtgacctgc
    36541 gtgcgcggcg ccgccctgga cgtggtcgtc gacctgcgcg tcggctcccc gacgttcggc
    36601 atgttcgaca ccaccctgca ggaagccggc tccggcatcg gcgtctacct cgccgacggc
    36661 ctcggccacg ccttcctcgc cctgagcgac gacacctgca tgaactacct gtgctcccag
    36721 gagtacgtgc ccggcaccat ggtcgacatc caggccctcg accccgacat cggcatcccc
    36781 tggaacacca ccggacaact catccgctcc gacaaggaca cccacgcccc cagcctctcc
    36841 gaggccgccg cccgcggcct gctgcccacc tacgaacagg ccctcgcctc ctaccacacc
    36901 gccgcccccg ccggccgccg cccgtaaccg ggccaccgcg tacgggagtc cgcagccctc
    36961 gcatccggcc cgggcccggc gtgctgcccg cccagcatcc cgggcaaccg gctgcgcggg
    37021 cccgcgcatg ctgattcgat ggcctgacgg gtgacgccgg cagcgggagg tgcgttgact
    37081 gctcccctcc ctgaagggag gggattcctt ccttcagggc tgagcgggga ttcctggctc
    37141 aggctgcctc tgggagcggc gctcccggtg gtcttacgcc ctcggcgcca gccgggttca
    37201 gacctgcccg gacgagcatc acgcgggcgg agttcttgtc tctgggggag acgactccgc
    37261 atgcggtgca ggtgtaggtc cgctcggaca acggcagtgc gtgcttggtt ctcgctccgc
    37321 acgatgcgca gtccatggtg gtgtgcgcgg gatgcacgag gcggatgtcc cgtccgtgct
    37381 tgcggcccat ctcgatcagg gccttcttcg tggcgccgat cgcggcgtcc gccgccttgc
    37441 gcgccatcga ggacctggcg aggaacttcg gcctgaagtc ctcgacggcg atggcgtcgt
    37501 ggtcgaccac ggccttcttc gcccacttgc ggccggtgtc ctgccgctgc cgggcgatct
    37561 tcgcgtaggt cttcgcccgc cacttcttcg cctcgcggta gcccttcgag gcggcctgcc
    37621 ccttcttcgg ccggcggcgg gccatcatcc ggtcgtaacg ggtcagccca gcctgcgcct
    37681 tacggccgtg ctgggcgtgc ggcaggtcgt gggcgttgga ggtggtggtc gcggtctcct
    37741 tcacgcccca gtccacgccg agcatccggc cggtctccgg cagcggctgc acctcggtgg
    37801 ggaccacgaa cgatgcgtac cagtgcccga cgctgtcttg gtacacgcgc accgaggaag
    37861 gttcgcccgg caggtcgcgc gaccacacca ccgtcagcac gatcccaccc gccaaatgca
    37921 ggcggtcgtc cttcagccgg aacccgcgcc gggtgtagtt cagcgtcggc aaggcctcgc
    37981 gcttcttctt ccaccgcggc ataccggccc gctgccgctg aggcaggcgt tcccggatgt
    38041 ccttgtgcgc cttcgcgcgg gacttgccga agtcccggat cagctgctgc tgaggaactg
    38101 agctgccctc gcgcagccac ggcgtacgct cccgcgcccc ggtcagcatc ttgtcgagct
    38161 gcgccgggcc acaggtccgc ttctctcccg tggtcttgtg gtgcaggtgg accgccttgg
    38221 acttggcgac gcactcgttc cagatccacc ggcaccgtgc ccactccgcc tccagcgcgg
    38281 tacgggcgct cgacgacacg cgaagccggt aggtgtaccg ggcgtgcccg gccccgtcgg
    38341 cttccatggg cgtcgtcatg atgccaccgt agcgtcatga ttcgcttctc actccggatc
    38401 ccggcagacc tgcacgaaca ggtgaccgcc cgcgccgctg cggaccggcg gtccctcaac
    38461 tccgagatcc tgcacctcct ggaggtcgcc ctcaccgctc cccggccgga cgccggatcg
    38521 cccagcggcg atccggcgtc ccctgccccg ctccgcggga aaccggattc ctccccggcc
    38581 tgaaggccag ggcatcctcc gggaatcccg gtgatcgagt gtgtccgggc ggtactggtc
    38641 acgcccgccg gccggctgct gctgatccgg cgcacctggc cgggcgccac gccctaccgg
    38701 gtctttcccg gcgggcacgt cgaaccggac gatccgggcc tgcgcgcggc cctggtccgt
    38761 gagatacgcg aagagaccgg cgccgagccg cagatcacgg gcctgctgca catgctggcc
    38821 gacgcgcacc agcgccagta cttctacctg gcccgcatcc ggtcatggtc cgaggcggac
    38881 cgcaccggtc cggagttcgc cgacccggac cgcggagagt accggctcga ggaagtcccg
    38941 ctgagcgtcc aggcgctcga cgccctcagc ctggagccgg aggagattgc cgcactgctg
    39001 cgcgccgcgg tgacggccgg gaccgagctg gccgccctgg cggatccggc acggtgagtc
    39061 cggcggccgg caccaggaac ccctccgcca ggagcctggc cgtcggcggc cgccgggtgt
    39121 gaaccggcct gccctgtccg caggttggag cgagcccggc gcagggccac acacgcttcc
    39181 tctcgcggcc tggcgggatc tccactcacc ccggaacggg agggcgcgga gaaatcaggt
    39241 tgatcagcat ccggccagtc gatcaggcgc ggaccccgca cgctgtggcg aaggccatcg
    39301 ttccgcaggc gggaggcgag gagggcgtca actcctgccc gcccggggag tgcggccgcg
    39361 cacgggcacc cgccacttct gttgaaagtg cgaaccggtt tgctccggtc gccgatcggg
    39421 gggcaccgac ctaacctcgg ttgaggccga cagtgaccaa tggggcagtt gttcaagatg
    39481 ggagaacatc gtgaatgaca cattccgcag ccactggggg cgcaccttcg ccgtaggaac
    39541 cctgacagcg gccctgctgt ccgggggaac agcgggcggt accgcgatag cggccaccgg
    39601 atcccagcat ccggccgcac ccgcggcgac accttcgaca tcggcgccgg aaacgtcgaa
    39661 gacgacgacc accgcgccga cgccgacgac aaccaccaag ccgtcgccca cgacgaccac
    39721 caagccgtcg cctacgacga ccaccaagca ttcgccgaaa ccgtcgccgt cgaagaccca
    39781 caaatattcg ccgaagccga ctccgtcgaa gacccacaag tactcgccga agccgaagcc
    39841 gactccgtcg aagacgcaca agtacacgcc gaagccgact ccgactccgt cgaagaccca
    39901 caagtacacg ccgaagccga agccgactcc gtcgaagacg cacaagtaca cgccgaagcc
    39961 gaagccgtcg aagacggcgc acccgaccat gaccgccaag ccgaccaaga cctcctagcc
    40021 ctgaccgccg gggcaagtga cacgcccgcg cccctgatgc gcgggcgtgt ctgccggagc
    40081 cttcgccctc ccccctcgca caaccatccg gcgtccggta cgtctgatgc ggtatgaggg
    40141 cgtggtggac gggcaggaag cggcggtatg cggccgtggt gtgtgcagtg gtactggcgg
    40201 cggccggggc aggcgccgtc gccctgaaaa cccgtcaccc ggcgcaggcg cccggggccg
    40261 tgctgacgtt ccggtccgtg ctgaacacgt tctacctgcc gcgctacacc gcgcccggcc
    40321 atgccccctg ggcccccgaa taccggatcc gcttggcggc ggccgcggcc ccgtccagag
    40381 ggagccaggg gtccgccagg caggtcgagg cggatttcga cctgtccgtc ttcaagggga
    40441 aggccgacat ctggggggag aacaagggct acggctgcgc ccggtcgggc tttcgcgtga
    40501 cctgcgcgct gccggacatc aagtacgggg agggagctga tttccttccc ttccaggtga
    40561 agccgaagcc cggtacggcc ttgggcccgg ccggatccat cgtggtgacc gtgcacagcg
    40621 ccgacgcgcc caccatccgg cacaccaccc gtgtgacggt cggctcgccg tatctgacca
    40681 cccggaacag gaaactgacg ggggtgcgcc ccgggggcga ggtgcggctg acacccgcct
    40741 tcggcaatcg gggggacacc ggtgtcgacg gtggcatcac cgtcgtggtg gtggcggacg
    40801 gcagcaccct gctgccccgg tacggcaact gccgctacaa caaggcggca gcggccaccg
    40861 aggcacaatg cgactttccc ggcccgctgc ctgcggggac ggcgtacgag acggaccatc
    40921 cggtcatcgc cgtgaccggc caggacacga ggagcggcag cctgcactac agcgtgtggc
    40981 ccaccgccga tatcgacggt ccgtcacaac ttcccgggcg ggctgtgcgc ggcaccggtg
    41041 aagtgctgcg gcttcggccg gtgaacggcg gcgcgttcac cgggagcgag tcgcgcagga
    41101 gccggggagc cgccggggca gtggacttcg agaccacgcg ggtcgacgac gtggaggccg
    41161 tcggtttcac catccggggc agggtgggcg aggaggtccg gaccgaggtg ccgtatccga
    41221 ggggctacag gggcgacacg atgtgggtga cgctccccga cggcgtcagc ctcgtcaccc
    41281 ggccaccgca agacctgcag agcgaggact cctactgccg aaagggcccg gcgaagggcg
    41341 gccccgtcgc ctgcgggccg ggggccgagc cctacgccgt cgtcctgctg gtgcgtatcg
    41401 acaagcgcgt cgaaggggcc cgcggcagcg tcacggtccc gcccggtccc gccgccgacc
    41461 cggaccagga caacaacaca gccccggtga ccgtggagta catcccgtga ccgtcccgtg
    41521 ccgcaacggg cgcccggtca tccgaactgg ccgggctggt agtcgccggc gggctgccgg
    41581 acgaggacgt tcacgcggtt gtaggcgttg atgagggcga tgagggagac cagcgcggcg
    41641 agttggtcct cgtcgtagtg cttggcggcg ttcgcccagg cctcgtccgt gaccccgccg
    41701 gccgcgtccg cgatgcgggt gccctgttcg gtcagctcca gggcggcgcg ttcggcgtcg
    41761 gtgaagaccg tggcctcgcg ccaggccgcg accaggttga ggcgcaccgg ggtctccccg
    41821 gcgtgcgcgg cgtccttggt gtgcatgtcg gtgcagaaac cgcagccgtt gatctggctg
    41881 gcgcggatct tcaccagttc ctgcgtcgcg gccggcagcg ccgcgtccga gaccgctttg
    41941 cctgccgagt tgatgtgcct caggaccttg cctgcgaccg ggttgccgaa gaggttcaag
    42001 cgggcgtcca tggtgagctc ctgtgccgtt ggcggtggtg acaccttcct gacggaccag
    42061 cccggcagga tgtgacagga acgcaaggaa ggcgtcttct ccgggcccgg tgccgccccc
    42121 gggagcgcgc tcaccggctc acagggcggc tttgtgcttc aggggttccc accaggcgcg
    42181 gtggtcgcgg taccaggcga aggtctcggc caggccctgg gcgaagtcct tgcgggggcg
    42241 gtagccgagc tcgcgggaga tcttcgtgca gtccaccgag tagcgcaggt cgtggccgag
    42301 ccggtcgggc acgtgctcga cgctgtccca ggtcgccccg gcgaggtcga tcagcagggt
    42361 ggtcagttcc
//
