LOCUS       NZ_BMUQ01000020        11362 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence20, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000020
VERSION     NZ_BMUQ01000020.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 215667)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 184062
            Orig. end                         :: 195424
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11362
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11362
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11362
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6362](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6362
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(492..505)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.17"
                     /tool="antismash"
     gene            525..1406
                     /locus_tag="IE289_RS38170"
                     /old_locus_tag="GCM10010317_078640"
     CDS             525..1406
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983654.1"
                     /locus_tag="IE289_RS38170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078640"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_190173040.1"
                     /transl_table=11
                     /translation="MIIPVRRFVATCALGALGVVLAACGTPGTPHAARPGHPASASGST
                     DAQPSRPPTLAPGSSGITPVFTNGPRTQDKTVALTFDADMTADEGPRAAAGEHFDNPEL
                     IATLRAFKVPATLFMTGRWADEYPKEARAIGQDPLFEVANHSYSHYAFTDNCYGLPTVP
                     QERMRAEVEEAYAAFKRAGVPHAMPYFRFPGGCYDQQALRTLSAVGVTAVQWDVVSGDA
                     FATDADAVARQVLEGVKPGSVVVMHCTRSAAPVTEQALRTIVPELRKKGFRFVKVSEMI
                     GSATQGERHGTT"
     gene            1438..1626
                     /locus_tag="IE289_RS38175"
                     /old_locus_tag="GCM10010317_078650"
     CDS             1438..1626
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049036.1"
                     /locus_tag="IE289_RS38175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078650"
                     /product="hypothetical protein"
                     /protein_id="WP_190173041.1"
                     /transl_table=11
                     /translation="MSDDYCATPAAPTPAPDPTDAGPPFAECVLCRKPTEYPESHKGIT
                     LCPVCEWQEAQRTACSG"
     gene            1694..2449
                     /locus_tag="IE289_RS38180"
                     /old_locus_tag="GCM10010317_078660"
     CDS             1694..2449
                     /GO_function="GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983656.1"
                     /locus_tag="IE289_RS38180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078660"
                     /product="peptidyl-tRNA hydrolase"
                     /protein_id="WP_373306542.1"
                     /transl_table=11
                     /translation="MSSDPTVADAPGRPDVPGSAEDSPFRSERTARDEAPQFVLPLVVR
                     IEKAAPPARTDALETAARAVLMILSDERALGDGEWAQAVRDWQDARIRKVVRRARGAEW
                     RRAEALPGITVTGKSAEVRVFPPVPLDGWPKDLVKLQVSGTDLDDPEPPVDADPTAPVL
                     WLNPDLDMSAGKTMAQAGHGAQLAWWALSDEQRAAWRDAGFPLAVRTADPARWSGLTTS
                     GLPLVRDAGFTEIAPGSCTVVADHPALRS"
     gene            2506..3150
                     /locus_tag="IE289_RS38185"
                     /old_locus_tag="GCM10010317_078670"
     CDS             2506..3150
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852511.1"
                     /locus_tag="IE289_RS38185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078670"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_190173043.1"
                     /transl_table=11
                     /translation="MAGTRLDGRVERGNRTRQLVLRRTVDIASVEGLEALSVGRLATEL
                     QLSKSGVFALFGSKQELQLATVREAARIYVEQVIRPASETPAGVARTWRLCELWLDYSQ
                     GRVFPGGCFFYEVIAEFDARSGPVHDAVAEAQRDWAAHVEHTITEARDLDELRSDTDAA
                     QLSFELIALMETANAVSVLRDETDVYRRARVAILSRLRAAATDPSLVPEPS"
     gene            3267..3905
                     /locus_tag="IE289_RS38190"
                     /old_locus_tag="GCM10010317_078680"
     CDS             3267..3905
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073957.1"
                     /locus_tag="IE289_RS38190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078680"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_190173044.1"
                     /transl_table=11
                     /translation="MTSTGVDIVELDRIAVYESLRLVGLARGTDWERDTPCAGWTLRRL
                     VAHMAAQHHGFAAAARGAGHETAYWREPEDMSDPERTYRGAATAVLAAFTEPGVTEGEF
                     VLPEIRDGDGFPGGMALGFHFVDYVVHAWDVAATLGVGLELPDHVLGAALAVARLVPTD
                     PAGREPGFAFAPPVDVPMGADPLDEALRLLGRTPEKWPLSADGPDSQLI"
     misc_feature    4025..4038
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            4025..4813
                     /locus_tag="IE289_RS38195"
                     /old_locus_tag="GCM10010317_078690"
     CDS             4025..4813
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983657.1"
                     /locus_tag="IE289_RS38195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078690"
                     /product="DUF4142 domain-containing protein"
                     /protein_id="WP_180292832.1"
                     /transl_table=11
                     /translation="MRRINGSAFVIAALAATVGALAFPVWSYADRAGTGQANLAAGTVN
                     TQWGPLSAADRDLIVRVRLAGLWELPAGQQALERAPNKAIKEVGDHLIVGHTDLDKRVR
                     VIAAQLNVELPNQPNAQQQGWLQEMTAATGAEYERKFVNLLRAAHGKIFPAIGAVRNST
                     RNTLVRQLASDANQTVLDHITILEKTGSVDFDAIANDTAALSTASPTGPPAPAAGVTAP
                     SAPPVQPGDGVVVTSSPSPAPPGQVNTARPEPSDPDNVLR"
     gene            5001..6362
                     /locus_tag="IE289_RS38200"
                     /old_locus_tag="GCM10010317_078700"
     CDS             5001..6362
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009317893.1"
                     /locus_tag="IE289_RS38200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078700"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_190173045.1"
                     /sec_met_domain="DUF692 (E-value: 8.9e-98, bitscore: 320.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPRRLGTGIGWRPEIAEAVERMPGIDWVEAVAENLCSGHLPES
                     LLRLRERGVTVVPHGVSLGLGGADRPEESRLAALAERAEALGSPLVTEHIAFVRAGGAL
                     TASPSLEAGHLLPVPRTRDALDVLCENVRIAQEALPVPLAVENIAALISWPGEEMTEGQ
                     FLYDLVDRTGVRLLIDVANLHTNHVNRAEDPSKALDELPVEAIAYVHVAGGFERDGVWH
                     DSHAHPVPRQVLDILADLASRVAPPGVLLERDENFPDPGELERELGAIRVTLTKARARV
                     VTPSETPAGPHSGEAAAPASGTPGAAGSHAAGVAVGARQRLALGQAALLSALVAGTPVP
                     EGFDRGRLGVQARALAAKRADVVAKVAVELPEILGDAYRPVFLAYAQGHPMSGGYRRDA
                     LDFAEYMLLAGHPEDAETRRRLRAWWLERSGPTPPSPRPTARLARATRRVLLRR"
     misc_feature    complement(6581..6597)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.02"
                     /tool="antismash"
     misc_feature    6626..6642
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            6645..7400
                     /locus_tag="IE289_RS38205"
                     /old_locus_tag="GCM10010317_078710"
     CDS             6645..7400
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983659.1"
                     /locus_tag="IE289_RS38205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078710"
                     /product="DUF4142 domain-containing protein"
                     /protein_id="WP_099920187.1"
                     /transl_table=11
                     /translation="MRSINRTGLVSGTGLIIAALTATLAALIFPIWSYADRAGTGLDTL
                     NAQSVSTQFGPLSALDREFITKVRLAGLWELPAGQQAEERGTTQAVKTAGAHLVEGHTF
                     LDARVRNVAARLGLELPNQPNAQQRGWLATLDAAHGTDYDQKFANILRRAHGKVFSVVA
                     QVRANTRNSLVRDLADDANTTVLDHIKVLEATGYVDFDALAQDAATASPPPLTASPAPP
                     GPTASPDSPVPVTPTGTYPLPPAASRPKS"
     misc_feature    7433..7448
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            7522..8310
                     /locus_tag="IE289_RS38210"
                     /old_locus_tag="GCM10010317_078720"
     CDS             7522..8310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063321.1"
                     /locus_tag="IE289_RS38210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078720"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_067375490.1"
                     /transl_table=11
                     /translation="MFWVLLLLLAWAAAGISCTRLCLAAVRAAAVDADAARGHHLTLYE
                     AAFLSGGPARVADLTLVSMARQRRLLLAHTGWATVVDPRGRDEMERSVIGAIGPQGQSR
                     IAPVRASTAAADSVRRLADRLVAAGLAVPDGARTTVASAIRQVQAAAAAVLALGAVAVL
                     MPSQSRASENDVPIAVWFSLPLILTVSCLAIARIEVHPYTRWASPAGQRLLGTLARHPD
                     ATGDDRTYLTSVAVRGVRAVGEPELRAAFAHRDRSPERQR"
     gene            8431..10089
                     /locus_tag="IE289_RS38215"
                     /old_locus_tag="GCM10010317_078730"
     CDS             8431..10089
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (113-483). E-value:
                     3.9e-18. Score: 57.9. Matches aSDomain:
                     nrpspksdomains_IE289_RS38215_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564416.1"
                     /locus_tag="IE289_RS38215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078730"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_190173046.1"
                     /sec_met_domain="PF00561 (E-value: 5.2e-24, bitscore: 79.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAVLYGTTGSLLLSGLVAAPAGGAAAWPNPAAALEARGTVVAA
                     ARAARAGIHWGACPKGDDFPVKMRCGTVTVPLDYAQPDGKKIKLTVSRAGATGKDLRNS
                     KHKVPRQGSLVYNPGGPGASGMYFPLIGFLPEWKRIASAYDLVGYAPRGVDRSAPLSCK
                     DPKHFLKGPAQSPTNPSETYKKERIAKAQAYARGCLKRSGQGIRHYTSLNNARDLDVLR
                     AALGERKLTFMGASYGTYFGALYATLFPSHVRRMVFDSAVNPAPRQIWYRNNLDQSAAF
                     EARWADFRAWVARHDKEYALGTTPEAVLHNYEKARARLAAAPAGGKVGPRQLQGAFLEA
                     GYFDDYWPQRALALSAYLKGDPKPLIQQAGPHPEASAEAENGNAVYTAVECNDAAWPTD
                     WRTWDRDNTRLARVAPFETWDNAWMNLPCAYWPVPRQKPLDVRTLPGALAPVLILAAER
                     DAATPYEGAVELQRRLSGSVLVTENGAGTHGIAGGPNQCVNGYLDAYLLEGRLPKRRAA
                     CAPHAEPEPAAPGGDKTTRHDAQDREDAKKTRQAP"
     aSDomain        8770..9879
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS38215_Abhydrolase_1.1"
                     /evalue="3.90E-18"
                     /label="IE289_RS38215_Abhydrolase_1.1"
                     /locus_tag="IE289_RS38215"
                     /protein_end="483"
                     /protein_start="113"
                     /score="57.9"
                     /tool="antismash"
                     /translation="LVYNPGGPGASGMYFPLIGFLPEWKRIASAYDLVGYAPRGVDRSA
                     PLSCKDPKHFLKGPAQSPTNPSETYKKERIAKAQAYARGCLKRSGQGIRHYTSLNNARD
                     LDVLRAALGERKLTFMGASYGTYFGALYATLFPSHVRRMVFDSAVNPAPRQIWYRNNLD
                     QSAAFEARWADFRAWVARHDKEYALGTTPEAVLHNYEKARARLAAAPAGGKVGPRQLQG
                     AFLEAGYFDDYWPQRALALSAYLKGDPKPLIQQAGPHPEASAEAENGNAVYTAVECNDA
                     AWPTDWRTWDRDNTRLARVAPFETWDNAWMNLPCAYWPVPRQKPLDVRTLPGALAPVLI
                     LAAERDAATPYEGAVELQRRLSGSVLVTEN"
     gene            complement(10090..10821)
                     /gene="hemQ"
                     /locus_tag="IE289_RS38220"
                     /old_locus_tag="GCM10010317_078740"
     CDS             complement(10090..10821)
                     /EC_number="1.3.98.5"
                     /codon_start=1
                     /gene="hemQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564417.1"
                     /locus_tag="IE289_RS38220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078740"
                     /product="hydrogen peroxide-dependent heme synthase"
                     /protein_id="WP_054233999.1"
                     /transl_table=11
                     /translation="MSDDAPTTESGRVPNKGKLAKDLNEVIRYTLWSVFKLKDVLPEDR
                     AGFADEVQELFDQLAAKDVTVRGTYDVSGLRADADLMIWWHAETSDQLQEAYNLFRRTR
                     LGRALEPVWSNMALHRPAEFNRSHIPAFLADETPRNYVSVYPFVRSYDWYLLPDEDRRR
                     MLADHGKMARGYPDVRANTVASFSLGDYEWMLAFEADELYRIVDLMRHLRASEARMHVR
                     EEVPFYTGRRKSVAELVAGLA"
     misc_feature    complement(10861..10876)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.09"
                     /tool="antismash"
ORIGIN
        1 gcggaccaga gcctgacgac gccgctcttc gccgatgccg tcctaggacc ggaggcccac
       61 cagacgatcg gcgggttcgt gtcctcggcc ttgtcccagt ccgtgacctc cacccgtcgc
      121 agttcgtcgg agggacagag cgggatcttg acgacgatcg tctccccttc ggccctggcc
      181 ccggccaccg tcgtgtccgc cggatccgac ggccccagga agcatccgct cgccagcagg
      241 gcgatcacgg tgaagaggag aaccggtgga gcaacgcgtc gccggttcgg caccggtacc
      301 caccccgtct cgcgtcggtc ctgccgttcg gatcggtcgc gacaggggtt cgatcccgca
      361 cgcggacacg ggaaaaggga accggcgtac gcgaccgacg cacgagacgg cgtgagaggc
      421 ggcgtgcgtc tcgccgggtc cagccgggtg acttccgcgc ccccaccgac gggcacgtgc
      481 ggacaatggg cgaatagtaa gtattgccca catatcttca tcgggtgatc attccagtac
      541 gacgattcgt cgcgacctgc gccctcggcg cactcggggt cgtgctcgcc gcctgcggga
      601 ccccaggaac cccgcacgcc gcccgcccag ggcaccccgc gtcggcctcc ggcagcacag
      661 acgcccagcc ctcgcgaccc cccacactcg cccccggctc cagcggtatc acccccgtct
      721 tcaccaacgg tccgcgcacg caggacaaga ccgtcgcgct gaccttcgac gcggacatga
      781 ccgccgacga gggtccacgc gccgcggccg gggagcactt cgacaacccc gaactgatcg
      841 ccacgctgcg cgcgttcaag gtgccggcga ccctgttcat gaccggacgc tgggccgacg
      901 agtaccccaa ggaggccagg gccatcgggc aggacccgct gttcgaggtc gccaaccact
      961 cgtacagcca ctacgccttc accgacaact gctacggcct gcccaccgtg ccccaggagc
     1021 ggatgcgggc cgaggtggag gaggcctacg ccgccttcaa gagggcgggc gtgccccacg
     1081 cgatgcccta cttccggttc cccggcgggt gctacgacca gcaggccctg cgcacgctga
     1141 gcgccgtggg cgtgaccgcc gtgcagtggg acgtcgtcag cggggacgcc ttcgcgaccg
     1201 acgccgacgc cgtggcccgg caggtgctgg agggtgtgaa gcccggatcc gtcgtcgtca
     1261 tgcactgcac gcgcagcgcg gctccggtga ccgaacaggc cctgcggacg atcgtccccg
     1321 agctacggaa gaagggtttc cgcttcgtga aggtctccga gatgatcggc tcggcgacgc
     1381 agggcgagcg gcacggcacc acgtaggcgt gctccggtcc cggcctacgc tggggccatg
     1441 agcgacgact actgcgccac cccggcggcc cccaccccgg caccggaccc gaccgacgcc
     1501 gggccgccgt tcgccgagtg cgtgctgtgc cggaagccga ccgagtaccc ggagtcgcac
     1561 aaggggatca cgctgtgccc cgtctgcgag tggcaggagg cacagcggac cgcctgttcc
     1621 gggtgacggt gacgatgacg gtggcatgac cgctcgccga agaaccgatc ttccgcctgg
     1681 cacactggag ggcgtgagca gcgacccgac cgtagccgac gcacccggcc gacccgacgt
     1741 acccggctcg gccgaggaca gccccttccg atccgagcgc accgcgcgcg acgaggcccc
     1801 gcagttcgtg ctgccgctgg tcgtgcgcat cgagaaggcc gctcccccgg cacgcacgga
     1861 cgcgctggag accgcggccc gcgccgtgct gatgatcctc agcgatgagc gggccctcgg
     1921 ggacggcgag tgggcgcagg cggtgcgcga ctggcaggac gcccggatcc gcaaggtcgt
     1981 acgaagggcg cgcggcgccg agtggcgacg ggccgaggct ctgcccggca tcacggtgac
     2041 cgggaagtcc gccgaggtgc gcgtcttccc gccggtcccc ctggacggct ggccgaagga
     2101 cctggtcaag ctccaggtct ccggcaccga cctcgacgac ccggagccgc cggtggacgc
     2161 ggacccgacg gcgccggtgc tgtggctcaa tcccgatctc gacatgtcgg ccggcaagac
     2221 gatggcgcag gccgggcatg gcgcgcagct ggcctggtgg gcactgtcgg acgagcagcg
     2281 ggcggcctgg cgtgacgccg gtttccccct cgccgtccgc accgccgacc cggcccgctg
     2341 gagtggactc accacctccg ggctgccgtt ggtgcgcgac gccgggttca cggagatcgc
     2401 gccggggtcg tgcacggtgg tggccgacca tccggcgctg cgctcctgac cgaccccgac
     2461 cgatcccgac cgaccctgag tgacctacgg acccgaggag gcgcgatggc cgggacccgg
     2521 ctggacggca gggtcgaacg cggcaaccgc acacggcagt tggtgctccg ccgcacggtc
     2581 gacatcgcct cggtcgaagg actggaagca ctgtccgtgg gccgtctcgc caccgagctc
     2641 cagctcagca agagcggggt cttcgcgctc ttcggctcca agcaggaact gcagctggcc
     2701 accgtgcggg aagcggcgcg catctacgtc gagcaggtga tccggcccgc gtccgagacc
     2761 cccgccggtg tcgcccggac ctggcggctg tgcgaactct ggctggacta ctcccagggc
     2821 cgggtcttcc ccggcggctg tttcttctac gaggtcatcg ccgagttcga cgcccggtcg
     2881 gggcccgtgc acgacgccgt cgcggaggcc cagcgggact gggcggccca tgtggagcac
     2941 accatcaccg aggcccggga cctggatgag ctgcgctccg acacggatgc cgcgcaactc
     3001 tccttcgagc tcatcgcgtt gatggagacg gcgaacgcgg tgtcggtgct gcgcgacgag
     3061 acggacgtct atcgcagggc ccgcgtcgcc atcctttccc ggctgcgcgc ggcggcgacc
     3121 gacccgtccc tcgtgcccga gccctcctga cctgccgagc tctcccgacc cgccgagctc
     3181 tcccgatctg ccgagccttc gacgcgggaa ccgtcacagc ggaaaacaag tagcacgatc
     3241 gttcgctcgg ttttatgctc ggccgtatga catcgaccgg agtggacatc gtcgagctcg
     3301 accggatcgc cgtgtacgag tcgctgcggc tcgtcgggct ggcgcggggc acggactggg
     3361 agcgggacac accgtgcgcg gggtggacgc tgcggcggct ggtggcacac atggccgcgc
     3421 agcaccacgg gttcgcggcc gccgcccggg gagcggggca cgagacggcg tactggcggg
     3481 agccggagga catgagcgac ccggagcgga cctaccgggg agcggcgacg gcggtgctgg
     3541 ccgctttcac cgaaccgggc gtgacagagg gggagttcgt gctgccggag atcagggacg
     3601 gggacgggtt ccccggcggg atggccctgg gcttccactt cgtcgactac gtggtgcacg
     3661 cgtgggacgt cgccgccacg ctcggcgtcg gactcgaact gccggaccac gtcctcgggg
     3721 cggccctggc cgtcgcccgc ctcgtaccga cggatccggc cggtcgcgag ccggggttcg
     3781 cgttcgcgcc gccggtcgac gtgcccatgg gcgcggatcc gctggacgag gcactgcggc
     3841 tgctcggacg tacaccggag aagtggccgc tgtcggccga cggcccggat tcacagctga
     3901 tttgacctga atcgagggtt cgctttagcc gcgcttgaac attcccggcg ccccgcacgt
     3961 atctcacgtc gctggccaag tacaggtttc caacgaccag ttggtttccc ccgggaggct
     4021 cattttgcgg cgtatcaatg gttctgcctt cgtcatcgcg gcgctcgccg ccacggtcgg
     4081 cgcgctcgcg ttccctgtgt ggtcgtacgc cgaccgcgcc ggcacggggc aggcgaacct
     4141 ggcggcgggg acggtgaaca cacagtgggg gcccctgtcc gccgccgacc gcgatctgat
     4201 cgtgcgcgtg cggctggccg gactctggga gctgccggcg ggacagcagg cgctcgagcg
     4261 ggcccccaac aaggcgatca aggaggtggg cgaccacctg atcgtcggcc acaccgacct
     4321 cgacaagcgg gtgcgggtca tcgcggccca gctcaatgtc gagctgccga accagccgaa
     4381 cgcgcagcag cagggctggc tgcaggagat gaccgcggcg acgggcgcgg aatacgaacg
     4441 gaagttcgtg aacctgctgc gggccgcgca cggcaagatc ttcccggcga tcggcgcggt
     4501 ccgtaactcc acccgcaaca cgctggtccg gcagctggcc tcggacgcca accagaccgt
     4561 gctcgaccac atcaccatcc tggagaagac cgggagcgtc gacttcgacg ccatcgccaa
     4621 cgacacggcg gccctgtcga ccgcgagccc gaccggcccc ccggcgccgg ccgccggcgt
     4681 cacggcgccc tccgcgccgc cggtgcagcc gggcgacggc gtcgtcgtca cgtcgagtcc
     4741 gtcgcccgcg ccgccggggc aggtcaacac cgcccggccg gagccctcgg atccggacaa
     4801 cgtgctgcgg tagccggtgc ggccgtcggc gcctcggggc gccgtcggaa cctcaaatgt
     4861 tgctctgaac gtccggcgac ttgggttcgg ccccggttcc cggggccatg actccgtcac
     4921 gccggaacac gggtccgtcg tgagcagaca gcggccaggg tcgcagcagc cggggttcga
     4981 gcggtgacgg aggaggcgac atgacacagc cgaggcggct ggggacgggc atcgggtggc
     5041 ggccggagat cgccgaggcc gtggagcgca tgcccggcat cgactgggtc gaggccgtgg
     5101 cggagaacct gtgctccggg catcttcccg agtcgctgct gcggctgcgc gagcggggcg
     5161 tcacagtggt gccgcacggg gtctcgctcg gcctcggcgg cgcggaccgg cccgaggagt
     5221 cccggctcgc cgccctcgcg gagcgggccg aggcgctggg ctcgccactc gtcacggagc
     5281 acatcgcgtt cgtacgggcc gggggcgcgc tcaccgcgtc gccctcgctg gaggccgggc
     5341 acctgctgcc ggtcccccgc acccgggacg ccctcgacgt gctgtgcgag aacgtccgca
     5401 tcgcgcagga ggcccttccc gtcccgctcg cggtcgagaa catcgccgcg ctgatctcct
     5461 ggcccgggga ggagatgacc gaggggcagt tcctgtacga cctggtggac cgcaccggcg
     5521 tacgcctcct catcgacgtg gccaacctcc acacgaacca cgtcaaccgg gccgaggacc
     5581 cttcgaaggc cctcgacgaa ctccccgtcg aggccatcgc ctacgtccac gtcgccggcg
     5641 gcttcgagcg ggacggcgtc tggcacgaca gccacgccca ccccgtcccc cggcaggtcc
     5701 tcgacatcct ggccgacctc gcctcccgcg tggccccacc gggggtcctc ctggagcgcg
     5761 acgagaactt cccggacccg ggcgaactgg agagggagct cggggcgatc agagtcaccc
     5821 tgacgaaggc gcgggcacgg gtcgtgacgc cgtccgaaac cccggcaggc ccgcactccg
     5881 gtgaggccgc cgcccctgcg agcggcaccc ccggggcagc cgggagccac gcggccggcg
     5941 tggccgtggg tgcgcggcag cggctggcgc tcgggcaggc cgcgctgttg tccgcgctcg
     6001 tcgcgggtac ccccgtgccc gaggggttcg accgggggcg gctgggtgtg caggcgcggg
     6061 cgctcgcggc caagcgggcg gacgtcgtcg cgaaggtggc ggtggagctg ccggagatcc
     6121 tcggggacgc gtaccggccg gtgttcctcg cgtacgcgca agggcatccg atgagcggtg
     6181 ggtaccggcg cgacgcgttg gacttcgccg agtacatgct gctcgcgggg caccccgagg
     6241 acgcggagac gcggcggcgg ctgcgtgcgt ggtggctgga gcggtccggc ccgaccccgc
     6301 cgtcgccgcg gcccacggcc cggctggccc gcgcgacccg acgggtactg ctgcgccgct
     6361 gaccccgccc gcgtcacagg agccgacacg cactcctacg cgcgccgtag tgcctcgccc
     6421 cggcagagtg tgccggggtt aacaccggac cccgtccgac cggatccgac gtccgttttc
     6481 cagggtttcc tgacggtctg gactccggtc gaaccacccc attcagcgcc ttcctcccac
     6541 ccggcaaccc ctactcctcg tacggcagtt ggcgtagtgc ccgaagtaat atgccaaccc
     6601 gcacccgtag cgcactagcg tgcggtgccg caacaggagg caccatgcga tccatcaacc
     6661 gcaccggatt ggtcagtggg acaggactca tcatcgcggc cctcaccgcg accctcgccg
     6721 ccctgatctt tccgatctgg tcgtacgcgg accgcgccgg caccggcctg gacaccctga
     6781 acgcccagtc cgtgtcgacg cagttcggtc cgctgtccgc actggaccgg gagttcatca
     6841 ccaaggtccg gctcgccggg ctgtgggagc tgcccgccgg ccagcaggcc gaggagcgcg
     6901 gcaccaccca ggccgtgaag acggcgggcg cgcacctcgt cgagggccac acgttcctcg
     6961 acgcgcgcgt ccgtaacgtc gccgcacggc tcggactcga actcccgaac cagcccaacg
     7021 cccaacagcg cggctggctg gccacgctcg acgccgcgca cggtacggac tacgaccaga
     7081 agttcgcgaa catcctgcgc agggcgcacg gcaaggtctt ctccgtcgtc gcccaggtcc
     7141 gcgcgaacac ccgcaactcc ctcgtacggg acctcgccga cgacgcgaac accaccgtgc
     7201 tcgaccacat caaggtcctc gaagccaccg ggtacgtgga cttcgacgcc ctcgcccagg
     7261 acgccgcgac cgcgagcccg cccccgctga cggcttcccc ggccccgccg ggtcccaccg
     7321 cgtccccgga cagccccgtc cccgtcaccc cgaccggaac ctatccactg cccccggccg
     7381 cgtcccgccc caagagctag catcgcggcg cccctcgggg agcgcctcgg cgggcaccgg
     7441 aacgtcacag agccacaacg ctccgtccat atcgtgggca taccgtggcg ccgacctgga
     7501 ctcctcgcgt agaaacacgc catgttctgg gtccttctcc tgctcctggc ctgggccgcg
     7561 gccggtatct cctgcactcg gctgtgcctg gccgccgtgc gcgcggcggc ggtcgacgcc
     7621 gacgcggcgc gcggacacca cctcacgctg tacgaggcgg cgttcctgtc cggcggcccc
     7681 gcccgggtcg ccgatctgac cctggtgtcg atggcccgtc agcggcggct gctgctcgcg
     7741 cacacgggct gggcgaccgt cgtggacccg cgcggtcgcg acgagatgga gcgctcggtg
     7801 ataggggcga taggtccgca ggggcagtcc cggatagcgc ccgtacgggc gagcacggcc
     7861 gccgcggact ccgtacgccg cctcgccgac cgtctcgtcg ccgcgggcct cgccgtgccc
     7921 gacggcgccc gcaccaccgt cgcgagcgcc atccgccagg tccaggccgc cgccgcggcc
     7981 gtcctcgcgc tcggcgccgt cgccgtgctg atgccctccc agtcccgggc gagcgagaac
     8041 gacgtgccga tcgccgtgtg gttctcgctg ccgctcatcc tcaccgtgag ctgcctcgcc
     8101 atcgcccgca tcgaggtcca cccgtacacg cgctgggcct ccccggccgg acagcggctg
     8161 ctcggcaccc tcgcccggca ccccgacgcc accggcgacg accgtacgta cctcacctcg
     8221 gtcgccgtac gcggcgtccg cgccgtcggc gagccggagc tgcgcgcggc cttcgcgcac
     8281 cgcgaccgaa gccccgagcg gcagcgctga gggcgcccga gggggcgcat aggggtcatt
     8341 ggggccgaca ccggcaccag gtgctttact tcatcaactg acgaaccaaa catccctttt
     8401 gtcgctgccg tgcgccgaag gggatacgcg atgagagctg ccgtcctgta cggaaccacc
     8461 gggtccttgc ttctgagcgg cctcgtcgcc gcccccgcgg gcggtgcggc ggcctggccg
     8521 aaccccgcgg ccgccctcga ggcgcgcggc accgtcgtcg ccgccgcccg tgccgcgagg
     8581 gccggcatcc actggggcgc ctgccccaag ggggacgact tcccggtcaa gatgcgctgc
     8641 ggcacggtca ccgtgccgct ggactacgcg caacccgacg gcaagaagat caaactgacc
     8701 gtcagccgcg ccggcgccac cggcaaggac ctgcgcaact ccaagcacaa ggtgccgcgt
     8761 cagggctccc tcgtctacaa cccgggcggc ccgggcgcgt ccggcatgta cttcccgctg
     8821 atcggcttcc tccccgagtg gaaacgcatc gcgtccgcgt acgacctcgt gggctacgcc
     8881 ccgcgcggcg tggaccgctc ggccccgttg tcctgcaagg acccgaagca cttcctgaag
     8941 gggcccgcgc agtcgccgac gaacccctcg gagacgtaca agaaggagcg catcgcgaag
     9001 gcacaggcgt acgcccgcgg ctgcctcaag cgctccgggc agggcatccg gcactacacc
     9061 tcgctcaaca acgcccggga cctcgatgtg ctgcgcgccg cgctgggcga gcggaaactg
     9121 acgttcatgg gggcgtcgta cggcacgtac ttcggcgccc tgtacgcgac gctcttcccc
     9181 tcgcacgtac gccggatggt gttcgactcg gcggtgaacc ccgccccccg gcagatctgg
     9241 taccggaaca acctcgacca gtcggccgcg ttcgaggccc gttgggcgga cttccgcgcg
     9301 tgggtcgcca ggcacgacaa ggagtacgcg ctcggcacca cgcccgaagc ggtgctgcac
     9361 aactacgaga aggcgcgggc acggctcgcc gcggcgcccg cgggcggcaa ggtggggccg
     9421 cgtcagttgc agggcgcgtt cctggaggcg gggtacttcg acgactactg gccgcagcgc
     9481 gccctggcgc tgtccgccta tctgaagggc gacccgaagc cgctgatcca gcaggccggg
     9541 ccgcatccgg aggcgtcggc cgaggcggag aacggcaacg cggtgtacac ggccgtggag
     9601 tgcaacgacg cggcctggcc gacggactgg cgtacctggg accgggacaa cacgcggctc
     9661 gcgcgcgtgg caccgttcga gacctgggac aacgcgtgga tgaacctgcc gtgcgcctac
     9721 tggccggtgc cgcggcagaa gcccctcgat gtgcggacgc tgcccggggc gctggcgccg
     9781 gtcctgatcc tggcggccga gcgggacgcg gcgacgccct acgagggggc ggtggagctc
     9841 cagcggcggc tgtccggctc ggtcctggtg accgagaacg gcgccgggac acacgggatc
     9901 gcgggcgggc ccaaccagtg cgtcaacggc tacctggacg cgtatctgct ggagggccgg
     9961 ctcccgaagc ggcgcgcggc gtgcgcgccg cacgcggagc cggagccggc ggcgccgggc
    10021 ggtgacaaga ccacccggca cgacgcacag gaccgtgagg acgcgaagaa gacccgccag
    10081 gctccctgat caggcgagcc cggcgaccag ctcggccacg gacttacggc ggccggtgta
    10141 gaacgggacc tcctcgcgga cgtgcatgcg ggcctcggag gcgcgcaggt ggcgcatgag
    10201 gtcgacgatg cggtacagct cgtcggcctc gaacgcgagc atccactcgt agtcgccgag
    10261 ggagaacgag gcgaccgtgt tggcgcgcac gtccgggtag ccgcgggcca tcttgccgtg
    10321 gtcggcgagc atgcggcggc ggtcctcgtc gggcagcagg taccagtcgt aggagcgcac
    10381 gaaggggtag acgctcacat agttgcgcgg cgtctcgtcg gcgaggaacg ccgggatgtg
    10441 cgagcggttg aactcggcgg ggcggtgcag cgccatgttc gaccagaccg gctccagggc
    10501 tcggcccagc ctggtgcggc ggaagaggtt gtacgcctcc tggagctggt cgctggtctc
    10561 ggcgtgccac cagatcatca ggtcggcgtc ggcgcgcagc cccgacacgt cgtacgtacc
    10621 gcggacggtg acgtccttcg cggcgagctg gtcgaagagc tcctggacct cgtcggcgaa
    10681 gccggcgcgg tcctcgggca gcacgtcctt cagcttgaac acggaccaca gggtgtagcg
    10741 gatgacctcg ttgaggtcct tggccagctt gcccttgttc gggaccctgc cggactcggt
    10801 ggtgggggcg tcgtcactca tgaggctatt ctcccgctcc gccgtgcagg ctctgcaccg
    10861 ggttcgccct cagcgcctcc agtccggcgc ggtcgccgcc gagctggtcc acggcggcgt
    10921 acgcgctcgc gacgcacgcg gggatgccga ccccgtcgta cgccgcgccg cagacggcga
    10981 gccccgggag cttggccacg tgctcgcgga cgcgggctac gcgcgtgtgg tgcccgaccg
    11041 ggtactgcgg cagtccggcg tcccaccggg tcacccgggt cgccacgggc tcggcggcca
    11101 ggccggtggc ctcgcgcagg tcgtaccggg agacgtccac gaggtcggcg tcgtcgcggc
    11161 ccagcacctc cgtctcgccg taccgcccga cggaggtgcg caggacgagc aggtcggggt
    11221 tctcctcggc gatccagccc cacttctggg aggcgaaggt ggatgccttg atggtgtggc
    11281 cgtccaccgg cggcaccagg aaaccgctcc cttcggggag ggtgacgtcc gcgcgccggt
    11341 aggccagcgt caccagcgcc at
//
