LOCUS       NZ_BMUQ01000020        22340 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence20, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000020
VERSION     NZ_BMUQ01000020.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 215667)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 129803
            Orig. end                         :: 152143
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22340
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22340
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22340
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12340](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12340)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(153..704)
                     /locus_tag="IE289_RS37920"
                     /old_locus_tag="GCM10010317_078120"
     CDS             complement(153..704)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675706.1"
                     /locus_tag="IE289_RS37920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078120"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_054236796.1"
                     /transl_table=11
                     /translation="MTSSFEFHTYPARLSDAERDRALKALSDGVALGRLSHDTFVRRME
                     LALAARRSDELAVLIADLPTEGRWSKLVFGTVEAISGFTVRLRRAWQAERLPKLLLPHP
                     GNNYPLRIGRDPASGLRLNHETVSRVHAELSRQGGLWVLRDLGSTNGTTVNGRRVISAA
                     VVKEGDQISFGRMSFRLSSS"
     misc_feature    826..841
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.8"
                     /tool="antismash"
     misc_feature    900..917
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            974..2719
                     /gene="treZ"
                     /locus_tag="IE289_RS37925"
                     /old_locus_tag="GCM10010317_078130"
     CDS             974..2719
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133692.1"
                     /locus_tag="IE289_RS37925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078130"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_190173015.1"
                     /sec_met_domain="Alpha-amylase (E-value: 1.3e-12, bitscore:
                     42.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFEVWAPEADRMTLHCAGATRALERDPERAGWWTGDADAQDGTR
                     YGFAVDDGPVLPDPRSRRQPDGPDGLSAVVDQARYAWRTEWAGRPLPGAVLYELHVGTY
                     TPEGTLDAAAGRLEHLAELGVTHVELMPLCPFPGRHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDRAHELGLGVVLDVVHNHLGPSGNHLPAFGPYFTDTHQTPWGSAVNLDAPGSDEVR
                     AYLVDSALAWLRDFRLDGLRLDAVHALRDTRAMHFLEELSTAVDALADDLGRPLFLIAE
                     SDLNDPRLVTARAEGGLGLHAQWNDDFHHALHTALTGEGQAYYADFARSPFAALAKTLT
                     SGFFHDGTYSSFRGRRHGRPLERTRVSAHRLLGYSQTHDQIGNRAQGDRLSASLSPGML
                     ACAAALTLTGPFTPMLFMGEEWAAGTPWQFFTDHTDPELAQAVRRGRRREFAAHGWAEE
                     DVPDPQDPATRDRSCLDWSEPEKALHARVLAWYRDLIALRRRQPDLADPDLAAVKVAYD
                     DQARWLALRRGDVRVAVNLGEEAAAIPLGLRHARVLAAWEPVEAPDANGVLSVPGESCV
                     VLTQA"
     gene            complement(2747..3676)
                     /locus_tag="IE289_RS37930"
                     /old_locus_tag="GCM10010317_078140"
     CDS             complement(2747..3676)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071453.1"
                     /locus_tag="IE289_RS37930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078140"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_190173016.1"
                     /sec_met_domain="APH (E-value: 3e-22, bitscore: 73.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRRLVRSLLADSEAAGAGPDVRPVTEGGEHSTWW
                     VGTRHVLRLAPDRETAVRRRRELRLRDLVRPLVGVTVPTSVAHGDWAGGLPYTLDTRLP
                     GRSGEAQDVSAVGEADLAGLLTGLREVPVRQAEALGVPRAAPRSLEELRTAAERAAEGL
                     AAADEFDPGRLAQLTQPAAGQLAAQTAAAVLVHHDLKGEHLVVSADGRVRGVLGWAEAV
                     LGDPAEDIAGLAIAVGAPAAVRAATLADYGARPCLRGLWLSRCDTVIRLAERLRGRGEG
                     PLPLLRTQLGRAWEPILLERVTELPGDG"
     gene            complement(3744..4883)
                     /locus_tag="IE289_RS37935"
                     /old_locus_tag="GCM10010317_078150"
     CDS             complement(3744..4883)
                     /EC_number="3.4.11.9"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983601.1"
                     /locus_tag="IE289_RS37935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078150"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_099920150.1"
                     /transl_table=11
                     /translation="MTGTPARFTAGEPAPFTAGDYEARMRRAAEAAADAGLDGVLIAPG
                     PDLVWLTGYRPVETERLTLLVLRAGQDPVLVVPTLEAPDAAAAAPMLTLRDWTDGKDPY
                     EAAASLVGSDGRFGVSDNSWALHLLGLQRRLPDTRYVALTEALPMLRAVKDAAEVARLA
                     EAGAAADAAYEEIRKVPFAGRREADVAADLAELLRHFGHSQVDFTIVASGPNGANPHHE
                     AGERVIERGDMVVLDFGGLKHGYGSDTSRTVHVGEPDLEERRVHDVVRAAQEAGVAAVR
                     PGAACQDVDRAARAVITEAGYGEFFIHRTGHGIGVTTHEPPYMIEGEELPLVPGMCFSV
                     EPGIYLPGRFGVRIEDIVTVTEEGGWRLNTTSREMAIVD"
     gene            5077..5829
                     /locus_tag="IE289_RS37940"
                     /old_locus_tag="GCM10010317_078160"
     CDS             5077..5829
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308343.1"
                     /locus_tag="IE289_RS37940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078160"
                     /product="phosphodiesterase"
                     /protein_id="WP_190173017.1"
                     /sec_met_domain="Metallophos_2 (E-value: 5.6e-10, bitscore:
                     33.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLAHISDLHLDGTRRATERAERVRDRLWELPGRVDALLVTGDI
                     ADHGTEAEYEEAARLLRLRDGEPPFPVLTCPGNHDSRAAYRKALFGQPASEGPVNSVHV
                     FDDAAVLMCDSSIPGQDEGELDEETYAWIETTLDELDGAVPALLAFHHPPVALHHPLPD
                     AYQLRRPASLATLLERRPEVVGLITGHAHTPAATAFAGRPLVVGPGVTWTLRLPWEGEG
                     AADRDAPPGFAFHVLADDGRLTSHFRTA"
     gene            complement(5844..6482)
                     /locus_tag="IE289_RS37945"
                     /old_locus_tag="GCM10010317_078170"
     CDS             complement(5844..6482)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431961.1"
                     /locus_tag="IE289_RS37945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078170"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_190173018.1"
                     /transl_table=11
                     /translation="MEQAALRPKPMPGQDPGGDRSSTGTTKRPHAARRRGRRLMSLLFG
                     LLVATVLVLSGVGIGTVGATVIGMSRLADFQKRAGAAQGPSGRPSGPGQASGAPQAGGT
                     KSAPGGGSPVTSTAPEPAPGKAALGIEAVDAPDGGGALVVGVHIPGPGHTAGLVRGDTL
                     IAFGGARLGSAADLARAVSAADPGTTVTLGVRHANGNHQQLSTVPGIVT"
     misc_feature    6567..6579
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.88"
                     /tool="antismash"
     gene            complement(6576..7442)
                     /locus_tag="IE289_RS37950"
                     /old_locus_tag="GCM10010317_078180"
     CDS             complement(6576..7442)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996929.1"
                     /locus_tag="IE289_RS37950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078180"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_190173019.1"
                     /transl_table=11
                     /translation="MDPHLLRTYVTVARVASFSEAARELGYTQSAVSQHIAALEQDLGA
                     PLLTRRPVAPTAAGERLLEHAGPLLLRLDAARADVVRMVGAPEHGLTLAATPTALGSRT
                     LAALPAAGVTLRVLAREEIPAAVAQGGAELGLVDGLTAPNDPLRHPDVAPLTTYGVGEE
                     PVCVLLPETHPLARRDGLRLADLVDARWLDAPDAGMPLAHLRRANGSGGFRPALRYEGT
                     DARTLAALAAAGHGLTLLPRAAATGVPGAVAVPLVAPRLVHRTELVHSGSPRGAAAAVV
                     DTLLERV"
     gene            7560..8351
                     /locus_tag="IE289_RS37955"
                     /old_locus_tag="GCM10010317_078190"
     CDS             7560..8351
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071449.1"
                     /locus_tag="IE289_RS37955"
                     /note="Members of this family of hydrolases with an active
                     site Cys residue belong to MEROPS family C26.; Members of
                     this family of hydrolases with an active site Cys residue
                     belong to MEROPS family C26.; Members of this family of
                     hydrolases with an active site Cys residue belong to MEROPS
                     family C26.; Members of this family of hydrolases with an
                     active site Cys residue belong to MEROPS family C26;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078190"
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="WP_099920154.1"
                     /transl_table=11
                     /translation="MTNIAAQTARLALVGDRSPNVLAHTRVPLLLDALATRDRLVLDAY
                     WVPTEDAEDPAAVRGFDAVWVLPGSPYRSEAGTLTAIRTAREEGIPFLGTCGGFQHALL
                     EFARDVCGLTRVAHAEQDPDADDLLIEPLACSLLGHEAAVTIEPGSLAHSVMGAERTVE
                     RYFCAYGPTRHLDTLRAHGLRFSGHDEDGNVRIVELPGHPFFLGTLFQPEQYGDGSRPH
                     PIVRALARAAVAHAAVGELRELGAVGGADEVGAVGGRRQPV"
     gene            8395..10041
                     /locus_tag="IE289_RS37960"
                     /old_locus_tag="GCM10010317_078200"
     CDS             8395..10041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657046.1"
                     /locus_tag="IE289_RS37960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078200"
                     /product="hypothetical protein"
                     /protein_id="WP_190173020.1"
                     /transl_table=11
                     /translation="MSDHALRLLREQPHLAELAAFPFNFDLARADHGEAVRLASGGPLE
                     AVAGDDTGGTYFVCGDGSVLYADSEGSAGIIGNSVDEALEVLVGLPGWHDYLGLAPADG
                     EEKIRAAVAETEEEIREYHGIDDERTELRAGLGLPERSPVELIGLLHAALLRTEPDFLL
                     LNAEEGGAHDLLDRHPRPPLWEAVLARGRTDLTLLREGSAWDEVAGDRARRALALRAAQ
                     FDRREGDLPLLRHLLRHEAEASMTDELRLAAVLVGLHGHAEDLPLLYEVRETGFDTWCG
                     LGGMPEPGADPAELRSWARGLDDSLFGTDPADEPLFTWTGLAHEQGLVALARAALIRRL
                     DDIDFRAYRDAQDSKAIERRDASQLSPLVHEFEELGDTFQALRAQRMYVPLQTRAWDRV
                     SALLRLARLEREEGRFGAAIRTLTSLRDTLAEPDGGAGIGDSGSDNSLGHWQRTNLGAY
                     IVEEHYAVARTAATDTALADEVRAVTVAAGELLARLSGTARANVERHLAGTTDTHTDTY
                     TDTHTDIHTDTGANPDADLSAEPTPPQPSAG"
     gene            complement(10001..12340)
                     /gene="cyc2"
                     /locus_tag="IE289_RS37965"
                     /old_locus_tag="GCM10010317_078210"
     CDS             complement(10001..12340)
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535575.1"
                     /locus_tag="IE289_RS37965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078210"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_229889391.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-82, bitscore: 272.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPYPARLNPHLDEARAHTVEWARGMGMLEGSGIW
                     EQSDLDAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLETFKRTQDRDGGKAY
                     LDRLPLFMPLDLSTPVPEPENPVEAGLADLWARTVPSMSADWRGRFAVSTEHLLNESMW
                     ELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPASVAATRPLRVLMETFSD
                     GVHLRNDLFSYQREVEEEGELSNGILVLETFFGCTTQEAAETVNDILTSRLHQFEHTAL
                     TEVPALAAEKGLTPDQAAAVAAYTQGLQDWQSGGHEWHLRSSRYMNEGVVEGSRPLGSA
                     RFGISAVDVGALLSAAGAQRLRRYTHVPYQKVGPSLLPDFYMPFEPALSPHLDGARDRL
                     TGWMYEKGMLQEGVWDEDKLDAYDLPLCAAGIHPDATAETLDLGSQWLAWGTYGDDYYP
                     LVFGHRRDLAAAKTTTERLSACMPIDGEPTPVPANAMEHGLLDLWERTAAKMTPDERRK
                     LRGDVDKMTESWVWELSNQLQHRIPDPVDYLEMRRATFGSDLTLNLCRLGHGPKVPPEV
                     YRSGPVRSLENAAIDYAMLINDVFSYQKEIEYEGEVHNAILVVQNFFGCDYPTGLGIIH
                     DLMTQRMQQFQHVAAHELPVLYEDFKLSPEVRGIMDGYVVQLENWLSGILKWHQDCHRY
                     GAEDLARRAHGFLPDRAPAVPFPGTGAGTVPVPALSPQDMAETESPPDLTPRTAAGATP
                     SFTLPKGVGAAAEFSLPKAEAASAPH"
     gene            complement(12493..13659)
                     /locus_tag="IE289_RS37970"
                     /old_locus_tag="GCM10010317_078220"
     CDS             complement(12493..13659)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071439.1"
                     /locus_tag="IE289_RS37970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078220"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_099920155.1"
                     /transl_table=11
                     /translation="MSEPADAPVILSDEPGSFPWSVLAERHPALVRKVRDAFPYGPEQH
                     RALDALLKNATEGVIEPLGERAADREQWERWGGAEYFGRSWFDVPFLWSESYFYRQLLE
                     AVGYFTPGAWKGIDPFRPFKLAELDTPEADEELAALDPLTERPVEEREEALLHGSLWGN
                     RADLGFRLAAADGESDVVAQLVANDGESLRSLFAGGTLCLVADNSGRELIPDLLLIDHL
                     LHHRRVGRALLHVKPYPYYVSDATTADVVDALRHLTGAKGAAAESGHRLWAAMGDGRLT
                     VRAHPFSCAPLPYADMPDDLRREFAEADVTLVKGDLNYRRLVGDRRYPATTPFAEPTAY
                     FPGPVAALRTLKSDVIVGLDARTEAALDAAEGGRWRTSGTHALIQVRA"
     gene            complement(13737..15476)
                     /locus_tag="IE289_RS37975"
                     /old_locus_tag="GCM10010317_078230"
     CDS             complement(13737..15476)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999855.1"
                     /locus_tag="IE289_RS37975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078230"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_373306540.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.1e-53, bitscore:
                     174.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTVAAAQPSTATATGKAAVTPAAQAAAQAVAAPAERLIVGYKS
                     GAAEATSNSAASADAETKGKEAGENLDFTRRLGTGAALVGLGDRLGTKDVADVIAQYRA
                     DPQVAYAVPDRLNTPQADPNDTEYTKQWDLYEAKAGMNVPGAWSTSTGSGVTVAVIDTG
                     YVAHSDVAANIVAGYDFISDTAVSVDGDGRDSNPADPGDHYAANECGSGIPASDSSWHG
                     THVAGTIATVTNNNKGIAGIAYGAKISPLRVLGKCGGYDSDIIDAITWASGGTVSGVPA
                     NANVAKVINMSLGGSGACTSATQSAITAAVNRGTTVVVAAGNDNDNAAGYSPASCNNVI
                     TVAATGRSGSRASYSNYGSIVDISAPGGDMSTATANGIYSTLNSGTTTPSSESYAYYQG
                     TSMATPHIVGLVALMKSANPSLTPAQVETAIKNNARALPGTCSGGCGAGLADATKTVQA
                     VSGATTGTTFSNTTALSIPDNGSAVESSIAVGGRTGNAPSALQVGVDITHTYRGDLVID
                     LVAPDGSTYRLKSSSSSDSADNVNTTYTVDASSETANGTWKLRVQDVAASDTGKLNSWK
                     LTL"
     gene            15944..16888
                     /locus_tag="IE289_RS37980"
                     /old_locus_tag="GCM10010317_078250"
     CDS             15944..16888
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675694.1"
                     /locus_tag="IE289_RS37980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078250"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_190173022.1"
                     /transl_table=11
                     /translation="MTAHRTATAAAVAVAAPLLLLTWAAGPAQAHGAPTDPVSRVVACS
                     PEGGSNTGTAACRAAIAANGAPFTAWDNLRVAGVGGRDRQVIPDGQLCSGGLPAYKGLN
                     LARADWPSTRMTPGATFTLSYSSTIPHTGTFKLYLSKPGYDPTKPLKWSDLPTKPFATA
                     TDPALVNGAYRIKATLPSDRTGRQMLYTIWQNTSTSDTYYSCSDVVFPAASGGGAAAPT
                     TSSPARTTPTANRTAQRSQEPTATTATPADRSPSPAPETTAATTEVTAPDHLTPAADSS
                     SGGSNTLPLVAGAGGAVAFLLTAGVAITLRRRR"
     gene            complement(16907..17557)
                     /locus_tag="IE289_RS37985"
                     /old_locus_tag="GCM10010317_078260"
     CDS             complement(16907..17557)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657057.1"
                     /locus_tag="IE289_RS37985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078260"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_099920158.1"
                     /transl_table=11
                     /translation="MRTRSLLALLGTAAALSVSAIAPASADDTPVLTAGGAAVATGDVL
                     TASLASGTAATLYSSATGTSGVSCAASTFTASVTDNPTAPSAATESLSAHTFGSCTSNV
                     IGVLGVTSVTVNNLPYTTTVASDGTVTVTPAAGSTIQTTVVLRTLLGSINCVYQAPSLT
                     GTASNTDNSITFTNQAFAKSSGSSLCFSSGYFTAKYAPVSDTTQSGSPAVTVN"
     misc_feature    17867..17882
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            18221..18877
                     /locus_tag="IE289_RS37990"
                     /old_locus_tag="GCM10010317_078280"
     CDS             18221..18877
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996942.1"
                     /locus_tag="IE289_RS37990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078280"
                     /product="DUF6230 family protein"
                     /protein_id="WP_054236784.1"
                     /transl_table=11
                     /translation="MASSSDATASTDSTPENESGSGRRGRVRLRRAAVMAVPATAVAAG
                     LMILTAQGALGVQFAISGMPFTVTATELNGTGFEQFGNLDNMADGSPNAGDTGGQVLVI
                     TSAIKNATLTKLCQSVDLGGTNLVITAGGGTDKVQATNLTTDSTELSGDAAFNNIEIGN
                     DASTLDKAGVQGNKGVFSQQADTVHIGNLRQTNYATTAAVFKLPGLKLRFSDSGC"
     gene            18877..19296
                     /locus_tag="IE289_RS37995"
                     /old_locus_tag="GCM10010317_078290"
     CDS             18877..19296
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007502455.1"
                     /locus_tag="IE289_RS37995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078290"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_190173023.1"
                     /transl_table=11
                     /translation="MPAVRDLRSDFRRWRADRPFWGGLLLTLGGAEILLTEKASLKVVM
                     HIGMQGMAGYLLPTVMILCGLLILFNPTQRLFYSLLGILLSLGTWLTSNLGGFFIGLLL
                     GATGSCLAFGWLPHQEPRKRRLLRRRRRQQMATEA"
     misc_feature    complement(19473..19486)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.49"
                     /tool="antismash"
     gene            19524..20786
                     /locus_tag="IE289_RS38000"
                     /old_locus_tag="GCM10010317_078300"
     CDS             19524..20786
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999861.1"
                     /locus_tag="IE289_RS38000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078300"
                     /product="cytochrome P450"
                     /protein_id="WP_099920160.1"
                     /sec_met_domain="p450 (E-value: 7.7e-11, bitscore: 35.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTPSPLTGSPSPLVVDATGRDIHAEAARIRARGPATRVALPGGV
                     EAWAVSSPELLKRLLLDPRVSKDPRRHWPAWINGEISPEWPLFTWVAVQNMFTAYGGDH
                     RRLRTLVSTAFTARRTAALQPRIEEITSGLLDRIAEAGEHGEVVDLREEFCYPIPIQVI
                     SELFGLPEDKRADLRDLVDSIFHTSAQPEEVTGNYARLYAVLGELVAEKRESPGDDLTS
                     GLIASRDEGDGRLSEQELLDTLVLMVSAGHETTVNLIDNAVHALLTHPEQLAHLRAGRA
                     TWDDLIEETLRVEAPVASLPLRYAVEDLDLAELGGPDGTVIGRGEAILAAYAAAGRDPE
                     RHGKDADLFDVTRADKEHLAFGHGVHRCLGAPLGRLEARIALPALFDRFPDLRLAAPAS
                     DLEPVDSFISNGHRTLPARIL"
     gene            complement(20797..22095)
                     /locus_tag="IE289_RS38005"
                     /old_locus_tag="GCM10010317_078310"
     CDS             complement(20797..22095)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656080.1"
                     /locus_tag="IE289_RS38005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_078310"
                     /product="cytochrome P450"
                     /protein_id="WP_190173065.1"
                     /transl_table=11
                     /translation="MYGPGFAADPAAVYRRLRTAGPTAPVELAPGVRATLVTSYDAALH
                     VLRSPETFSKDPRRWRDLADGTVPPDSPVVPMMMYRPNALFTDGEQHERLRGAITDSLA
                     LVDPNTLRGYVERSADTLIDRFAPLGTADLLGEYAQVLPLLVFNHLFGCPAEYGVRLVE
                     GMSGIFDGVDAEKADELLTSTLVDLVALKRGKPGQDMTSWLMAHPADLTDEEMIHTLVV
                     LMGAGTEPQQNLIANSLRLLLSDERFAGDLSGGSLPVEDALDEVLWTDPPIANYAVHYP
                     LHDVVYEGAVLRASDPLVVSLAAANTDPALTVDQRAGNRAHLAWSAGPHNCPAQSPARL
                     IATAAVEKLLDRLPDVELGLPVGELSWRPGPFHRALTALPVRFPPTTTVQRPEGERQSY
                     ASPLPALVTEPPAPEPDRPRSGWTRLLSWWRGE"
ORIGIN
        1 caaatgtggt gccgtcgatt cacctgatgt acatggtgta cgcacagtca gtcacggctg
       61 tggaggtacg tcaacaccgt cgaacgtaag ggaatttaag gaaatcgctg agtgaaaccg
      121 aggccaaggc tcatgcgggt gcgggttgtc gctcaggagg aagagaggcg gaaggacatg
      181 cgtccgaagc tgatctggtc accctctttg acgacggcgg cgctgatcac ccgccgtccg
      241 ttgacggtcg tcccgttggt cgagccgagg tcgcgcagca cccacaggcc gccctggcgg
      301 ctcagttcgg cgtgtacgcg ggagaccgtc tcgtgattga gccgcagtcc gctcgcgggg
      361 tcgcggccga tccgcagggg gtagttgttg cccgggtggg gcagcagcag tttggggagc
      421 cgctcggcct gccaggccct gcgcagtcgt acggtgaagc cggagatcgc ctcgacggtg
      481 ccgaacacca gtttcgacca gcgtccctcg gtgggcaggt cggcgatgag cacggcgagc
      541 tcgtcggagc ggcgggcggc gagcgccagt tccatccggc ggacgaacgt gtcgtgcgag
      601 aggcgcccga gggcgacgcc gtcactgagc gccttcagcg cccggtcgcg ctccgcgtcc
      661 gacagccgcg cggggtacgt gtggaactcg aaagacgacg tcacggaggt gattgtcggt
      721 cagtaggagc ggggtgtcca gaagacccgg aaaaggccgc tgccgccgac aggtgggttc
      781 cacgcgtcca tcacgtggca aacacgcggc aaaagggtgg attcgaaagc gaattgatct
      841 cgtgtgaagc accatggacg tgctacgtca cgacatgttg cgtcactcac gtcgcgctct
      901 gtcacgaaga gcggacaacg gacaccaggc aatgggcaac gggcaacgga gagcggacaa
      961 gggggaaccg tctgtgcggt tcgaggtgtg ggcaccggag gccgaccgga tgacgctcca
     1021 ctgcgcgggc gccacacgcg cgctggagcg cgatccggag cgcgccggat ggtggacggg
     1081 cgacgcggac gcgcaggacg gcacgcggta cgggttcgcg gtggacgacg gccccgtgct
     1141 gcccgatcct cgttcgcggc ggcagccgga cggcccggac ggactgagcg cggtggtcga
     1201 ccaggcccgg tacgcgtggc gcaccgagtg ggcggggcgc ccactgccgg gcgcggtcct
     1261 ctacgagctg cacgtgggga cgtacacccc cgaaggaacg ctcgacgcgg ccgccgggcg
     1321 gctggagcac ctcgcggaac tgggcgtcac ccacgtcgag ttgatgccac tgtgtccgtt
     1381 ccccgggcgg cacggctggg ggtacgaggg ggtctccctg tgggccgtgc acgagccgta
     1441 cgggggcccg gaggcactga agcgttttgt cgaccgggcg cacgaactcg gcctgggtgt
     1501 ggtcctcgac gtcgtgcaca accacctcgg cccgtccggg aaccacctcc ccgcgttcgg
     1561 gccgtacttc acggacaccc atcagacgcc ctggggctcc gcggtgaacc tggacgcacc
     1621 gggttcggac gaggtgcgcg cgtatctcgt cgacagcgcc ctggcctggc tgcgggactt
     1681 ccggctggac gggctgcgcc tggacgcggt acacgcgttg cgggacaccc gcgcgatgca
     1741 cttcctggag gagttgtcga cggccgtgga cgccctcgcc gacgacctgg gccggccgct
     1801 gttcctgatc gcggagtcgg atctgaacga cccgcggctc gtcaccgcgc gcgcggaggg
     1861 cggtcttggg ctgcacgcgc agtggaacga cgacttccac cacgcgttgc acaccgcgct
     1921 gaccggtgag gggcaggcct actacgccga cttcgcgcgg tccccgttcg cggcgctcgc
     1981 gaagacgctg acgtccggct tcttccacga cggtacgtac tcgagcttcc gcggccgccg
     2041 ccacggccgc cccctggagc gtacgcgcgt ctcggcgcac cggctgctcg gctactccca
     2101 gacccacgac cagatcggca accgtgccca gggggaccgg ctgtcggcgt ccctctcccc
     2161 cggcatgctg gcctgcgcgg ccgcgctgac gctcaccggg cccttcaccc cgatgctgtt
     2221 catgggcgag gagtgggcgg cgggcacccc gtggcagttc ttcaccgacc acaccgatcc
     2281 cgagctcgct caggccgtac ggcggggcag gcggcgggag ttcgcggccc acggctgggc
     2341 cgaggaggac gtccccgacc cgcaggaccc ggcgacccgc gaccgctcct gcctggactg
     2401 gtcggaaccc gaaaaggcac tccacgcgcg tgtgctggcc tggtaccgcg acctgatcgc
     2461 cctgcgccgg cgtcagcccg acctcgcgga ccccgatctc gccgccgtca aggtcgccta
     2521 cgacgaccag gcccgctggc tggccctgcg gcgcggggac gtacgggtgg cggtgaacct
     2581 cggcgaggag gccgccgcga tcccgctggg gctgcgccac gcgcgtgtgc tggccgcctg
     2641 ggaaccggtc gaggcgccgg acgcgaacgg ggtgttgagc gtgcccggcg agtcgtgtgt
     2701 ggtgctgacg caggcgtgag cgcctggcgg cttcgcgcgc ccgggctcag ccgtcgcccg
     2761 gcagttccgt gacccgttcg aggaggatcg gctcccaggc gcgccccagt tgggtccgca
     2821 acagcgggag cgggccttcg ccgcggcccc gcaggcgctc ggcgaggcgg atcaccgtgt
     2881 cgcagcggga cagccacagg ccgcgcagac aggggcgggc tccgtagtcg gcgagggtgg
     2941 cggcgcgtac ggcggcgggg gcgccgacgg cgatcgcgag cccggcgatg tcctcggcgg
     3001 ggtccccaag gaccgcttcg gcccagccga ggacgccgcg cacccgcccg tcggcgctca
     3061 ccaccaggtg ttcgcccttg aggtcgtggt ggacgaggac ggcggccgcg gtctgcgcgg
     3121 ccagctggcc ggcggcgggc tgggtgagct gggcgaggcg tccggggtcg aactcgtcgg
     3181 cggcggcgag cccctcggcg gcccgctccg cggccgtccg cagctcttcc agggagcggg
     3241 gcgcggcccg tggcaccccg agcgcctcgg cctgccgtac gggcacctcg cgcagccccg
     3301 tgagcagtcc cgcgaggtcc gcctccccga ccgcggagac gtcctgagcc tcgcccgagc
     3361 ggccgggaag ccgggtgtcc agggtgtagg gcaggccgcc cgcccagtcg ccgtgcgcga
     3421 cgctggtcgg caccgtgacc ccgacgagcg ggcggaccag gtcgcgcagc cgcagctcgc
     3481 ggcgccggcg cacggcggtc tcacggtccg gggcgagccg cagcacatga cgggtgccga
     3541 cccaccaggt ggagtgctca ccgccctcgg tgacgggccg gacgtcgggt cccgcgcccg
     3601 ccgcctcgct gtcggcgagc agcgaacgga ccagtcggcg gacggtgtcc gcggtcggtg
     3661 tcggtgcctg ggtcatggtc gcgccgttgc cgtcgggggc cttggactgc cgggaggccc
     3721 tggggagtac tcctggtgac cggtcagtcg acgatcgcca tctcgcggga cgtggtgttg
     3781 aggcgccatc cgccctcctc ggtcaccgtc acgatgtcct cgatgcgcac cccgaagcgg
     3841 ccgggcagat agatgccggg ctccacggag aagcacatcc cgggcacgag gggcagttcc
     3901 tcgccctcga tcatgtacgg cggttcgtgg gtggtgacgc cgatgccgtg cccggtgcgg
     3961 tggatgaaga actcgccgta tcccgcctcg gtgatgacgg cgcgggccgc ccggtcgacg
     4021 tcctggcagg cggcccccgg ccggaccgcg gcgacgcccg cctcctgggc cgcgcgcacg
     4081 acgtcgtgca cccggcgctc ctcgaggtcc ggctcgccga cgtggaccgt gcgggaggtg
     4141 tcggagccgt agccgtgctt gagaccgccg aagtcgagga cgaccatgtc gccgcgctcg
     4201 atgacgcgct cgcccgcctc gtggtgcggg ttggcgccgt tcgggcccga ggcgacgatg
     4261 gtgaagtcga cctgggagtg cccgaaatgc cgcagaagct cggcgaggtc ggcggcgacg
     4321 tccgcctccc tgcgccccgc gaagggcacc ttccggatct cctcgtacgc ggcgtccgcg
     4381 gccgccccgg cctccgccaa ccgcgccacc tccgccgcgt ccttgaccgc ccgcagcatc
     4441 ggcagggctt cggtgagtgc cacgtaccgc gtgtccggca gccgccgctg gaggccgagc
     4501 agatgcaggg cccaggagtt gtcgctgacg ccgaagcggc cgtcgctccc gaccagggac
     4561 gcggccgcct cgtacgggtc cttgccatcg gtccagtcgc gcagggtcag catgggggcc
     4621 gccgctgccg cgtccggggc ctccagggtc ggcacgacca gcacggggtc ctgcccggcc
     4681 ctgagcacca gcagggtgag gcgttcggtc tccacgggcc ggtagccggt cagccacacc
     4741 aggtcgggcc cgggggcgat caggacgccg tcgagtcccg cgtccgcggc ggcctcggcc
     4801 gcgcgccgca tacgggcctc gtagtcaccg gcggtgaagg gcgcgggttc accggcggtg
     4861 aagcgcgcgg gcgtgccggt catccatgcc tccgtctgtc cggagtttcc ccaggggcta
     4921 cgggcagcat cctgcccgtt cgccgatgcg gacgcgagcc ggttgcggcc atggcgtcgg
     4981 tccgggagct caactaacgg ttgatcgttg ccagtccatt agtgctaatg gttggatgtg
     5041 gatgtcccat taacttccag ggggaggcct cgggccatgc tcgtactggc acacatcagc
     5101 gatctgcatc tcgacggcac ccggcgcgcg acggagcggg ccgagcgggt gcgggaccgg
     5161 ctgtgggaac tgccggggcg ggtggacgcc ctgctggtga ccggcgacat cgcggaccac
     5221 ggcacggagg cggagtacga ggaggcggcg cgtctgctca ggctgcgcga cggggagccc
     5281 cctttccccg tactcacctg cccgggcaac cacgacagcc gcgcggccta ccgcaaggcc
     5341 ctgttcgggc agcccgcgtc cgaggggccg gtcaacagcg tccacgtctt cgacgacgcc
     5401 gccgtcctga tgtgcgactc cagcatcccg ggccaggacg aaggagagct ggacgaggag
     5461 acgtacgcct ggatcgagac gacgctcgac gaactggacg gagccgttcc ggcgttgctc
     5521 gccttccacc acccaccggt ggcgctgcac catccgctcc cggacgccta ccagctacgc
     5581 cggccggctt ccctggccac gctgttggag cgcaggcccg aggtcgtcgg gctgatcacc
     5641 gggcacgcgc acacgcccgc cgcgaccgcc ttcgccgggc ggccgctcgt cgtcggtccc
     5701 ggggtgacct ggacgctgcg gctgccctgg gagggcgagg gggccgccga ccgggacgcg
     5761 ccccctgggt tcgcgtttca tgtactggcc gacgacgggc ggctgaccag ccacttcagg
     5821 accgcctgac cgtttcgtcg gcgtcaggtc acgatgcccg ggaccgtgga cagttgttgg
     5881 tggttgccgt tcgcgtggcg cacgccgagc gtgaccgtgg tcccggggtc cgcggccgag
     5941 accgcccgcg cgaggtcggc ggccgagccg agccgtgccc cgccgaaggc gatcagggtg
     6001 tcaccgcgga ccaggcccgc ggtgtggccc gggccgggga tgtgcacacc gacgacgagc
     6061 gcgcccccgc cgtcgggggc gtcgacggcc tcgatgccga gcgcggcctt cccgggcgcg
     6121 ggctccggtg ccgtcgaagt gaccggactc ccgccgccgg gcgccgactt ggtgccaccg
     6181 gcctgcggcg cgccggatgc ctgcccgggc ccggacggcc ggccggacgg cccctgcgcc
     6241 gcccccgccc gcttctggaa gtccgccagc ctgctcatac cgatcaccgt ggcgccgacg
     6301 gtcccgatgc cgacgcccga caggaccagc acggtcgcga cgaggagacc gaagagcagg
     6361 gacatcagcc gcctgccacg ccgtcgcgcg gcgtgcgggc gcttggtggt gccggtcgaa
     6421 ctccggtcac cgcccggatc ctgaccgggc atcggcttgg gacgcagtgc ggcctgttcc
     6481 atggatcgcc tccggcagat gctctacgga ccgccccccg gctcttgctc taccctgcgc
     6541 tccggcgcac gacgattcac gaacgagtga gactgtcaaa cacgttcgag aagtgtgtcc
     6601 accacggccg cggcggctcc gcgcggcgac ccgctgtgca ccagttccgt ccggtgcacc
     6661 aggcgcggcg ccacgagcgg cacggccacc gccccgggga cgccggtggc cgcggcccgc
     6721 ggcagcagcg tgagaccgtg cccggcggcg gccagggcgg cgagggtgcg cgcgtcggtg
     6781 ccctcgtacc gcagggccgg gcggaagccc ccgctgccgt tcgcccggcg gaggtgggcc
     6841 aggggcattc ccgcgtcggg ggcgtccagc cagcgggcgt cgacgagatc ggcgaggcgc
     6901 agcccgtccc gccgggcgag cggatgcgtc tcgggcagca gcacgcagac gggttcctcg
     6961 ccgacgccgt acgtggtcag cggggccacg tcgggatgcc gcaaggggtc gttgggcgcc
     7021 gtcagtccgt ccaccaggcc cagctccgcc ccgccctgcg cgacggcggc ggggatctcc
     7081 tcgcgggcca gtacccgcag ggtcaccccg gcggcgggca gcgccgcgag cgtgcgcgaa
     7141 ccgagcgccg tcggtgtcgc cgcgagcgtc agcccgtgct cgggcgcgcc caccatccgt
     7201 acgacgtccg cgcgggccgc gtccaggcgc agcagcagcg gcccggcgtg ttcgaggagc
     7261 cgctcgcccg ccgccgtcgg tgccacggga cgccgggtca gcaggggcgc gccgagatcc
     7321 tgctccagcg cggcgatgtg ctgggacacc gcggactggg tgtagccgag ttcccgtgcg
     7381 gcctccgaga aggaggcgac gcgggccacg gtgacgtatg tgcgcaggag atgcggatcc
     7441 atgcgctcca ggatcccgta cggggcctgt atctcctcag cacccccatc agcgttgctt
     7501 atcgaaggtg cagtaatcat cgttggacgt gaacgagcgg gcccgccgac gatgaggaca
     7561 tgacgaacat cgcggcgcag accgctcgcc tcgccctcgt gggcgaccgc tccccgaacg
     7621 tcctcgccca cacccgcgtc ccccttctcc tggacgccct ggccacccgc gaccgcctcg
     7681 tcctcgacgc ctactgggtc ccgaccgagg acgccgagga cccggccgcg gtgcgcggct
     7741 tcgacgcggt gtgggtgctg cccggcagcc cgtaccgcag cgaggcgggg accctcaccg
     7801 cgatccgcac cgcgcgcgag gagggcatcc cgttcctggg gacatgcggc ggattccagc
     7861 acgcgctgct ggagttcgcg cgcgacgtct gcgggctcac ccgtgtcgcg cacgccgagc
     7921 aggaccccga cgccgatgac ctcctcatcg aaccgctcgc ctgttccctc ctgggccacg
     7981 aggccgccgt caccatcgaa ccgggttcgc tcgcccactc cgtgatgggc gccgagcgga
     8041 cggtcgagcg ctatttctgc gcgtacggcc ccacccgcca cctcgacacc ctgcgcgccc
     8101 acggcctgcg cttcagcggc cacgacgagg acggaaacgt acggatcgtc gaactcccgg
     8161 gccacccctt cttcctgggc accctcttcc agccggagca gtacggggac ggctcacgcc
     8221 cgcacccgat cgtgcgggcg ctggcacggg ccgccgtggc acacgcggcc gtcggggagc
     8281 tccgggaact cggcgcggtc ggcggggccg acgaggtcgg cgcggtcggc ggacggcgtc
     8341 agcctgtgtg acggacggag ccgtttgtca gtgccggctg ttacgttcgg cggcatgagc
     8401 gatcacgccc tgcggctgct ccgggagcag cctcacctgg ccgaactggc cgcgttcccc
     8461 ttcaacttcg acctggcccg ggccgaccac ggcgaggccg tccggctcgc ctcgggcggt
     8521 ccgctggagg cggtggcggg ggacgacacg ggcggcacgt atttcgtgtg cggggacggc
     8581 tccgtgctgt acgcggactc cgagggctcc gccggaatca tcggcaacag cgtcgacgag
     8641 gcgttggagg tgctggtcgg gctgcccggc tggcacgact acctggggct cgcgccggcc
     8701 gacggcgagg agaagatccg cgcggcggtc gccgagacgg aggaggagat ccgggagtac
     8761 cacgggatcg acgacgagcg gaccgagctg cgggccggcc tcggcctgcc cgagcgctcg
     8821 cccgtcgagc tcatcggcct gctgcacgcg gccctgctgc gcaccgagcc cgacttcctc
     8881 ctcctgaacg cggaggaggg cggcgcgcac gacctcctcg accgccaccc ccgtccccca
     8941 ctgtgggagg cggtcctcgc gcggggccgt accgacctca cactgctgcg cgagggctcg
     9001 gcgtgggacg aggtggccgg ggaccgggcg cgccgggcgc tcgcactgcg cgccgcccag
     9061 ttcgaccggc gcgagggcga tcttccgctg ctgcggcatc tgctgaggca cgaggccgag
     9121 gcgtcgatga ccgacgaact gcggctcgcc gccgtcctgg tgggcctgca cggacacgcg
     9181 gaggatctgc cgctgctgta cgaggtccgt gagacgggct tcgacacctg gtgcggactc
     9241 ggcgggatgc ccgagccggg cgctgatccg gccgagctgc ggagctgggc gcgcggcctg
     9301 gacgactcgc tcttcggtac cgaccccgcc gacgagccgc tgttcacctg gaccggcctc
     9361 gcccacgaac agggtctggt cgcgctcgcc cgcgccgcgc tgatccggcg gttggacgac
     9421 atcgacttcc gggcgtaccg cgacgcgcag gacagcaagg ccatcgagcg ccgcgatgcc
     9481 tcccaactga gcccgctcgt ccacgagttc gaggagttgg gcgacacctt tcaggcgctg
     9541 cgcgcccagc ggatgtacgt gcccctgcag accagggcct gggaccgcgt ctcggccctc
     9601 ctcaggctcg cccggctgga gcgggaggag ggccggttcg gcgcggcgat acgcacgttg
     9661 acctcactgc gggacaccct cgccgagccg gacggcggcg ccggcatcgg cgacagcggg
     9721 agcgacaact cgctggggca ctggcagcgc accaacctgg gcgcgtacat cgtcgaggag
     9781 cactacgcgg tcgcccggac cgcggccacc gacacggcgc tcgccgacga ggtccgggcc
     9841 gtcaccgtgg ccgccgggga gctcctggcg agactctccg ggacggccag ggcgaacgtg
     9901 gagcggcacc tcgccggtac gaccgacact catacggata cctatacgga cacccatacg
     9961 gacatccaca cggacaccgg tgcgaacccc gatgccgacc tcagtgcgga gccgacgccg
    10021 cctcagcctt cggcaggctg aactccgcgg cggctcccac ccccttcggc agggtgaacg
    10081 acggggtggc gcccgccgcg gtccggggag tgaggtccgg cggggattcc gtctccgcca
    10141 tgtcctgggg actgagcgcc ggcaccggca cggtcccggc ccccgtcccg ggaaacggga
    10201 ccgcgggggc ccggtccggc aggaagccgt gggcccggcg ggccaggtcc tcggcgccgt
    10261 aacggtggca gtcctggtgc cacttcagga ttccggacag ccagttctcg agttgcacca
    10321 catagccgtc catgatgccg cgcacctccg gcgagagctt gaagtcctcg tacagaacgg
    10381 gcagttcatg ggcggcgacg tgctggaact gctgcatgcg ctgggtcatc aggtcgtgga
    10441 tgatgccgag gccggtcggg tagtcgcagc cgaagaagtt ctgcacgacg aggatggcgt
    10501 tgtggacctc gccctcgtac tcgatctcct tctggtacga gaagacgtcg ttgatcagca
    10561 tcgcgtagtc gatggcggcg ttctccaacg accggacggg accgctccgg tacacctcgg
    10621 gcgggacctt ggggccgtgg cccaggcggc acaggttcag ggtgaggtcg gagccgaagg
    10681 tggcgcggcg catctccagg tagtcgaccg ggtcggggat gcggtgctgg agctggttcg
    10741 acagctccca cacccagctc tccgtcatct tgtccacgtc accgcgcagc ttgcgccgct
    10801 cgtccggcgt catcttcgcc gccgtgcgct cccacaggtc gaggaggccg tgctccatgg
    10861 cgttggccgg gaccggggtc ggctcgccgt cgatgggcat gcaggccgag aggcgttcgg
    10921 tggtcgtctt ggccgccgcc aggtcgcggc ggtgtccgaa gaccagcggg tagtagtcgt
    10981 cgccgtacgt cccccaggcc agccactgcg agccgaggtc gagggtctcc gcggtcgcgt
    11041 ccgggtggat gcccgcggcg cacagcggaa ggtcgtacgc gtccagcttg tcctcgtccc
    11101 agacgccctc ctggagcatg cccttctcgt acatccagcc ggtgaggcgg tcgcgggcgc
    11161 cgtccaggtg ggggctgagg gccggctcga agggcatgta gaagtcgggg agcagggacg
    11221 ggccgacctt ctggtacggg acgtgggtgt acctgcgcag ccgctgcgcc ccggccgcgg
    11281 agagcagggc gccgacgtcg acggccgaga tgccgaaccg ggcgctgccg agcggccggc
    11341 tgccctccac caccccctcg ttcatgtagc gactggagcg caggtgccac tcgtggccgc
    11401 ccgactgcca gtcctggagc ccctgggtgt acgcggcgac ggccgcggcc tggtccgggg
    11461 tgagcccctt ctccgcggcg agtgcgggca cttcggtgag ggccgtgtgc tcgaactggt
    11521 gcaggcgtga ggtgaggatg tcgttgacgg tctcggcggc ctcctgggtg gtgcagccga
    11581 agaaggtctc caggacgagg atgccgttgc tgagctcgcc ctcctcctcg acctcacgct
    11641 ggtaggagaa caggtcgttg cgcagatgga ccccgtcgga gaacgtctcc atcagcaccc
    11701 gcagcgggcg cgtcgccgcg acggaggcgg gcacctcggc cgtcgcgtac tccacgagcc
    11761 ccgccgacca gggggcgccg cccaccttgc ggcgcatctc gatgtactcg acggggttgg
    11821 cgatccgtcc ctcgttgatg ttggagagct cccacatcga ctcgttgagc aggtgctccg
    11881 tggacaccgc gaaccgcccc cgccagtccg ccgacatcga gggcaccgtg cgcgcccaga
    11941 ggtcggcgag ccccgcctcg accggattct ccggctccgg tacgggggtc gagaggtcca
    12001 gcggcatgaa gaggggcagc cggtccaggt aggccttgcc gccgtcgcgg tcctgggtgc
    12061 gtttgaaggt ctccaggaag tggtcgtcga agaagaagac ccacacgtac cagtcggtga
    12121 tgagcgagag tgccgggccg tcgcagtcgg ggtgggtgta cgcacagagc agcccgtagt
    12181 cgtgcgcgtc gaggtcggac tgttcccaga tgccggagcc ctccaacatg cccatcccac
    12241 gggcccattc gaccgtgtgg gcgcgcgcct cgtcgaggtg cgggttcagc cgcgcgggat
    12301 acggcatgta gaagtgcggg agttcgaacg gctgcgtcat ggccgggccc tacccagggc
    12361 cctccggggg catccgccgg gcgggacatg atcacaccat cgcgtgaatt tacccctttt
    12421 cgaggcaagt gaatggcacg gcgacggggc ccacaaggtg atcgcgctgc acggctggtg
    12481 gccgcttggc cctcaggccc gcacctggat cagggcgtgt gtgccgctcg tgcgccagcg
    12541 tccgccctcg gccgcgtcga gggcggcctc cgtgcgggcg tccaggccga cgatcacatc
    12601 ggacttgagg gtgcgcaggg cggcgaccgg gcccgggaag tacgcggtgg gctccgcgaa
    12661 gggggtggtg gcggggtagc gccggtcgcc gaccagacgg cggtagttca ggtcgccctt
    12721 cacgagggtc acgtcggcct cggcgaactc acggcgcagg tcgtcgggca tgtcggcgta
    12781 cggcagcggg gcacaggaga agggatgggc ccggacggtg aggcgaccgt cgcccatggc
    12841 cgcccacagc cggtggccgg actcggccgc cgcccccttc gcgccggtga ggtgacgcag
    12901 ggcgtcgacc acgtcggcgg tcgtggcgtc cgagacgtag tacgggtacg gcttcacgtg
    12961 caggagcgcc cgcccgacgc ggcggtggtg gagcagatgg tcgatcagga gcagatcggg
    13021 gatgagttcc cggccggagt tgtccgcgac caggcagagg gtgccgcccg cgaacaggga
    13081 acgcagcgac tcaccgtcgt tggcgaccag ttgggcgacg acgtccgatt ccccgtccgc
    13141 ggcggcgaga cggaagccga ggtccgcgcg gttgccccac agcgagccgt gcagcagcgc
    13201 ctcctcccgc tcctcgaccg gccgctcggt gagcgggtcg agcgcggcga gttcctcgtc
    13261 cgcctccggg gtgtcgagtt ccgcgagttt gaaagggcgg aaggggtcga tgcccttcca
    13321 ggcgccggga gtgaagtagc cgacggcttc gaggagttgg cggtagaagt agctctcgga
    13381 ccagaggaag ggcacatcga accaggagcg gccgaagtac tccgcgccgc cccaccgctc
    13441 ccactgttca cggtccgcgg cccgctcgcc gagcggttcg atgactccct cggtggcgtt
    13501 cttcagcagg gcgtcgagcg ctcggtgctg ctcggggccg tacgggaagg cgtcccgcac
    13561 cttccggacg agggccggat gccgctcggc cagcacgctc caggggaacg agcccggctc
    13621 gtcgctgagg atcacgggcg cgtcggcggg ttcagacatg tggctcacgg taccggccga
    13681 gccgaaaggg gcggcccacg ccgcgcgtgg gccgcccctc cccccgtggg ccgcgctcag
    13741 agggtcagtt tccagctgtt gagcttgccg gtgtccgacg cggccacgtc ctggacgcgg
    13801 agtttccatg tgccgttcgc ggtctcactg gacgcgtcga ccgtgtaggt ggtgttgacg
    13861 ttgtccgcgg agtccgagct gctggaggac ttcaggcggt acgtcgagcc gtccggggcg
    13921 accaggtcga tcaccaggtc accgcggtag gtgtgggtga tgtcgacgcc gacctggagg
    13981 gcggagggcg cgttgccggt gcggccgccg acggcgatcg aggactcgac ggccgacccg
    14041 ttgtccggga tcgagagggc ggtggtgttg gagaaggtcg tgccggtggt cgcaccgctc
    14101 acggcctgca cggtcttcgt cgcgtccgcg aggcccgcgc cgcagccgcc ggagcaggtg
    14161 ccgggcaggg cacgggcgtt gttcttgatg gccgtctcga cctgagccgg ggtgagcgag
    14221 gggttcgccg acttcatgag cgcgaccagg cccacgatgt gcggggtggc catgctcgtg
    14281 ccctggtagt acgcgtacga ctccgaggag ggggtcgtcg ttccggagtt cagcgtggag
    14341 tagatgccgt tggcggtggc ggtgctcatg tcgccgccgg gggccgagat gtcgacgatc
    14401 gaaccgtagt tggagtagga ggcccgggag ccgctgcggc cggtcgcggc gacggtgatg
    14461 acgttgttgc agctcgccgg ggagtagccg gcggcgttgt cgttgtcgtt gcccgccgcg
    14521 acgacgaccg tggtgccgcg gttcacggcg gcggtgatgg cgctctgggt ggccgaggtg
    14581 caggcgccgc tgccgccgag gctcatgttg atgaccttgg cgacgttggc gttggccggg
    14641 acgccggaga cggtgccgcc cgaggcccag gtgatggcgt cgatgatgtc ggagtcgtag
    14701 ccgccgcact tgccgaggac gcgcagcggg gagatcttcg caccgtaggc gatgcccgcg
    14761 atgcccttgt tgttgttcgt gaccgtggcg atggtgcccg ccacgtgcgt gccatgccag
    14821 gaggagtcgc tcgccgggat gccggaaccg cactcgttcg ccgcgtagtg gtcgcccggg
    14881 tcggccgggt tgctgtcgcg tccgtcgccg tcgaccgaga ccgccgtgtc ggagatgaag
    14941 tcgtatccgg cgacgatgtt cgcggcgacg tcggagtgcg ccacgtaacc ggtgtcgatg
    15001 acggcgaccg tcaccccgct gccggtggag gtggaccagg caccggggac gttcatgccc
    15061 gccttggcct cgtacaggtc ccactgcttg gtgtactcgg tgtcgttcgg gtcggcctgg
    15121 ggcgtgttca ggcggtccgg tacggcgtag gcgacctgcg ggtcggcgcg gtactgcgcg
    15181 atgacgtcgg cgacgtcctt cgtaccgagc ctgtcgccga ggccgacgag ggccgcgccg
    15241 gtgccgaggc ggcgggtgaa gtcgaggttc tcgcccgcct ccttgccctt ggtctcggcg
    15301 tcggcggagg cggcggagtt ggaggtggcc tcggcggcgc cggacttgta gccgacgatg
    15361 aggcgctcgg cgggagcggc gacggcctgc gcggcggcct gcgccgccgg ggtgaccgcc
    15421 gccttgccgg tggcggtcgc ggtggacggc tgggcggcgg cgaccgtggt ggtcattccg
    15481 gccagcaggg ccgcggagac cgcggcgacg gatatcagct tccgtcggac ttctcgtgag
    15541 ggggcgggac gcaagggctt gcctttcgtg gccggctccg ggcggtgaag ggcgcggcgg
    15601 agcagcggtc gaatcgcttc gtcgtcgaag cggcgggggg gtgcagtcca gaagcggcgc
    15661 gggggccggc catacgtcgc gagcgacctg tcaggggttg cctgtgggtc ggctgtgccc
    15721 gaacgatagg caaagcccag gtaatacgga tacaggggaa accctcgatc tggccggtaa
    15781 ccgcccctca agggctcccc gttggccggg agtgcccggt ttcacctggc tcgcgcatct
    15841 gaacgcacgg ccctgtgccc ccgtacttca cggtgcggcc acgcctgcgc gcgatgccgt
    15901 acggccgcac ccgccgaccc caccccgcga ggagacccac cggatgaccg cacaccgcac
    15961 cgccaccgcg gccgctgtcg ccgtggcggc cccgctgctt ctcctgacgt gggccgccgg
    16021 tccggcccag gcgcacggcg cgccgacgga tccggtcagc cgggtggtgg cctgttcgcc
    16081 ggagggcggc agcaacaccg gtacggcggc ctgcagggcg gcgatcgcgg cgaacggcgc
    16141 gcccttcacc gcctgggaca acctccgggt cgccggtgtg ggcggcaggg accgtcaggt
    16201 gatcccggac gggcagctgt gcagcggggg tctgcccgcc tacaagggac tgaacctggc
    16261 ccgcgccgac tggccctcca cgcggatgac gccgggcgcg accttcacgc tctcctacag
    16321 ttcgacgatt ccgcacacgg ggaccttcaa gctgtatctg tccaagcccg ggtacgaccc
    16381 gaccaagcct ctcaagtggt ccgatctgcc gacgaaaccg ttcgccaccg ccaccgatcc
    16441 ggcgctggtg aacggcgcct accggatcaa ggccacgctg ccctccgacc ggaccggccg
    16501 gcagatgctg tacacgatct ggcagaacac gagcacgagc gacacgtact actcgtgctc
    16561 ggacgtggtc ttcccggccg cgagcggcgg tggggccgcc gcgccgacga cctcgtcccc
    16621 cgcgcgtacg acacccacgg cgaaccggac ggctcagcgg agccaggagc cgaccgcgac
    16681 cacggccact cccgccgacc ggtcaccgtc gcccgccccg gagaccaccg cggcgacgac
    16741 ggaggtgacc gcgcccgacc atctgacgcc ggccgcggac agctcgtccg gcggcagcaa
    16801 cacgctcccc ctcgtcgccg gggcgggggg agcggtcgcg ttcctgctca ccgcgggcgt
    16861 cgccatcacg ctgcgacgcc gtcggtgacc gggattccgg gacgggtcag ttgacggtga
    16921 ccgccgggct gcccgactgg gtggtgtcgg agacgggcgc gtacttcgcg gtgaagtagc
    16981 cgctgctgaa gcagagcgac gagcccgagg acttcgcgaa cgcctggttg gtgaaggtga
    17041 tgctgttgtc ggtgttgctc gccgtgccgg tcaggctggg cgcctggtag acgcagttga
    17101 tgctgccgag cagggtgcgc agcacgacgg tggtctggat ggtggagccg gcggccgggg
    17161 tcacggtgac cgtgccgtcg gaggcgaccg tggtggtgta cgggaggttg ttgaccgtga
    17221 cgctggtgac gccgagcacg ccgatgacat tgctggtgca actgccgaag gtgtgggcgc
    17281 tgagcgactc ggtggccgcg ctgggggccg tcgggttgtc ggtgacggag gcggtgaagg
    17341 tcgacgcggc acaggagaca ccgctcgtgc cggtcgcgct ggagtagagc gtggcggcgg
    17401 tgccgctcgc cagtgaggcg gtgaggacgt caccggtggc gacggcggct ccgccggcgg
    17461 tgagcacggg ggtgtcgtcc gcggaggcgg gggcgatcgc ggagaccgag agcgcggcgg
    17521 cggtaccgag gagggcgagc agggatcgag tgcgcatggg ggtgcctctt tctcagacgg
    17581 gggtgcgggt gggtacgagg ccgtcgcgga catgccgtca cggcggaccg ctgccggtcc
    17641 gtgacgcctt ctccttacgt cacggaccgg cagcggaagc cgggcgaccg gacacggctc
    17701 aggggggaaa gtgccgtgcc ggtgccgcgg ggggaggtgg tttcggcgtt ggagcgcacc
    17761 gcacgttcag acatgccacg gccaccccgc gaggagcggg gggtccagga ggtggcgtac
    17821 gtgccgcgca tcggatccgg cgccacggat ccaagggaaa ccatgcagag ttctagacct
    17881 gatgaatggt caacgtcaag gcgtagtaag gaagttgaag gtcaacgcgg ccccaagaac
    17941 gaggccgtgg ccgaccggcc acgagctcgt cgcgggaccg agtgcgaggt cggcgttgct
    18001 gggcctccac agttggcaca caatcaacat ccctttgcca caagtctctt gacccacgaa
    18061 tgtaaccccc ggtaacttcc acgtcggcta ctgctgcgta acgagaaagc ccttgcgacc
    18121 gccgggagtt gtgaggaggc gtgcgcggca gccgctgtcc gcgccaggac aacgtgcccg
    18181 ttgaagcccc acctgcatga ctatgtccag ggagcagaac atggcctcgt cctcggatgc
    18241 cacggcgtcc accgattcga cccccgagaa cgaaagcggt tccggcagac gcgggcgggt
    18301 ccgcctgcgc cgcgccgcgg tgatggcggt gcctgccacc gcggtcgccg cgggactgat
    18361 gatcctcacc gcccagggcg ctctgggggt gcagttcgcc atctccggca tgccgttcac
    18421 cgtcacggcc accgaactca acggcaccgg cttcgagcag ttcgggaacc tcgacaacat
    18481 ggccgacggc agcccgaacg ccggcgacac cggcggccag gtcctcgtca tcacctccgc
    18541 gatcaagaac gcgacactca ccaagctgtg ccagagcgtc gacctgggcg gtacgaacct
    18601 ggtcatcacc gcgggcggcg gcacggacaa ggtgcaggcg accaatctga cgaccgactc
    18661 gaccgagctg tcgggcgacg cggccttcaa caacatcgag atcggcaacg acgcgagcac
    18721 gctcgacaag gccggggtcc aggggaacaa gggcgtcttc agccagcagg ccgacaccgt
    18781 ccacatcggg aacctgcggc agaccaacta cgccaccacg gcggcggtgt tcaagctccc
    18841 cggtctcaag ctccgcttca gcgactcggg ctgctgatgc cggccgtccg ggatctgcgg
    18901 tccgacttcc ggcggtggcg tgcggaccgc cccttctggg gcgggctgct gctcaccctg
    18961 ggcggggcgg agatcctcct caccgagaag gcgtccctga aggtcgtcat gcacatcggg
    19021 atgcagggca tggcgggcta tctgctgccg acggtcatga tcctgtgcgg tctgctgatc
    19081 ctcttcaacc cgacgcagcg cctcttctac tccctgctcg gcatcctcct ctccctcggc
    19141 acctggctca cctccaacct cggcggcttc ttcatcggcc tcctcctcgg agcgaccggc
    19201 agctgcctgg ccttcggctg gcttccccac caggagccgc gcaagcggcg tctgctgcgc
    19261 aggcgccgcc ggcagcagat ggcgaccgag gcgtagggga agcggaacgc aaggggcccg
    19321 ccccggccga gctcagggca atgggcggcc ggggcggaag ctgtgacggt gcgactccag
    19381 gaggcgccct gtcctccgac ttgcttgtac gcgcagggaa tttgccctcg cacgcagtgg
    19441 acgccggacg gccgcatcgg ggaacgtcac cctcgcgtag cgtgacgcgc cgtaccgacg
    19501 tccgagcgcc agggaggctt ccgatgggaa ccccgagtcc cttgacgggc agcccgagcc
    19561 ccttggtggt ggacgcgacg ggccgtgaca tccacgcgga agcggcccgc atccgcgcgc
    19621 gcgggccggc gacccgtgtc gccctgcccg gtggcgtcga ggcctgggcg gtcagcagcc
    19681 ccgagctgct caaacggctg ctcctggacc cacgggtgtc caaggacccg cgccggcact
    19741 ggcccgcctg gatcaacggg gagatctccc ccgagtggcc gctgttcacc tgggtcgcgg
    19801 tgcagaacat gttcaccgcg tacggcggtg accacaggcg gctgcggacc ctcgtctcca
    19861 cggcgttcac ggcccgccgc acggccgcgc tgcaaccccg gatcgaggag ataacctccg
    19921 gcctcctcga ccgcatcgcc gaggccggcg agcacggcga agtcgtcgac ctgcgcgagg
    19981 agttctgcta tccgatcccc atccaggtga tcagcgaact cttcggactg cccgaggaca
    20041 agcgggcgga cctcagggac ctggtggaca gcatcttcca cacctccgcg cagcccgagg
    20101 aggtgacggg caactacgcc aggctgtacg ccgtactggg tgaactagtc gccgagaagc
    20161 gggagtcgcc tggcgacgac ctgacctccg gcctcatcgc gtcccgcgac gagggcgacg
    20221 gccggctgag cgagcaggag ctgctcgaca cgctggtcct gatggtcagc gccggtcacg
    20281 agaccacggt caacctcatc gacaacgccg tgcacgccct gctcacccac cccgagcagc
    20341 tcgcacacct ccgcgccgga cgcgccacct gggacgacct gatcgaggag accctgcggg
    20401 tcgaggcgcc cgtcgcgagc ctgccgctgc gctacgccgt ggaggacctc gacctcgccg
    20461 aactgggcgg tccggacggc acggtgatcg gccggggcga ggcgatcctc gccgcgtacg
    20521 ccgccgccgg acgcgatccc gagcgccacg gcaaggacgc cgacctcttc gacgtgactc
    20581 gggcggacaa ggagcacctc gccttcggac acggtgtcca ccgctgcctc ggcgccccgc
    20641 tgggccgcct ggaggcccgc atcgccctcc ccgccctctt cgaccgtttc cccgacctcc
    20701 gactcgccgc accggcatcg gatctggagc cagtggactc cttcatctcc aacggccacc
    20761 gcaccctgcc cgcccggatt ctctagaagc gggcgctcac tcgccgcgcc accaggacag
    20821 gagtcgggtc cagccgcttc gcgggcggtc gggctccggg gcggggggct cggtcacgag
    20881 agccgggagg gggctcgcgt acgactgccg ctcgccttcg ggccgttgga ccgtcgtggt
    20941 gggcgggaaa cggacgggca gcgccgtcag cgcgcggtgg aacgggccgg gccgccagga
    21001 caactccccc accggcaacc ccagttcgac atcggggagg cggtcgagga gcttctccac
    21061 cgcggccgtc gcgatcagcc gggccgggct ctgcgccggg cagttgtggg gtcccgcgct
    21121 ccaggccaag tgggcccggt tgcccgcccg ctgatcgacc gtcagggcgg gatcggtgtt
    21181 ggccgcggcg agactgacga ccagcggatc gctcgcgcgc agcaccgctc cctcgtacac
    21241 gacgtcgtgc agcggatagt gcacggcgta gttggcgatc ggcggatcgg tccacagcac
    21301 ctcgtcgagg gcgtcctcca ccgggaggct gccgccggac agatcgcccg cgaaccgttc
    21361 gtcggacagc aggagccgca ggctgttcgc gatcaggttc tgctggggct cggtgccggc
    21421 gcccatcagc accacgaggg tgtggatcat ctcctcgtcg gtgaggtccg cgggatgcgc
    21481 catcagccag gacgtcatgt cctgaccggg tttgccccgc ttcagcgcga cgaggtcgac
    21541 cagggtgctg gtcagcagtt cgtcggcctt ctccgcgtcc accccgtcga agatcccgga
    21601 catgccctcg accagccgga ccccgtattc ggccgggcag ccgaagaggt ggttgaagac
    21661 cagcagcggc aggacctgcg cgtactcgcc gagcagatcc gcggtgccga gcggcgcgaa
    21721 gcggtcgatg agggtgtcgg cgctgcgctc cacatagccg cgcagggtgt tcggatcgac
    21781 gagcgcgagg ctgtcggtga tcgcgccgcg cagcctctcg tgctgctcgc cgtcggtgaa
    21841 cagcgcgttg ggccggtaca tcatcatcgg cacgaccggg ctgtccggcg ggacggtccc
    21901 gtcggcgagg tcgcgccagc ggcgggggtc cttggagaag gtctccggac tgcgcaggac
    21961 gtgcagggcg gcgtcgtagg aggtgacgag ggtggctctg acgccgggtg cgagctcgac
    22021 gggtgcggtc ggtcccgccg tgcgcagccg ccggtagacg gcggctgggt cggccgcgaa
    22081 cccgggcccg tacaggggct cgtgcgccgg gcagccgggc ggtggcccgg acggtggtga
    22141 cacggacggt ggcggtacgg gcggtggtgg ttcggaggtc acacgggctc cagttcgccg
    22201 ctgcgggtca tcaggtactc gacgagggcg atcagcgcct cggtggacga gacccggtcg
    22261 cgggcgtcgc agcgcacgag cggggtcgag ggcagcaggt cgagggcctc gcgcacctcg
    22321 tccaggtcgt gcgccgcgga
//
