LOCUS       NZ_BMUQ01000019        21086 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence19, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000019
VERSION     NZ_BMUQ01000019.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 226249)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 138859
            Orig. end                         :: 159945
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            155..661
                     /locus_tag="IE289_RS36635"
                     /old_locus_tag="GCM10010317_075530"
     CDS             155..661
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="IE289_RS36635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075530"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_099920727.1"
                     /transl_table=11
                     /translation="MDIRIRHAHPHEYDRIGEITAQAYLGDGLLDFGESDEYLGELRDV
                     AKRATAAEVLVAVDHDHVLGAVTFVPRGGPMADIARPGEAEIRMLAVARESRGRGAGET
                     LVRACVDHARATAGCARVVLSTQRTMHAAHRIYERLGFTRTPDRDWNPLPDLDDITLLT
                     YELTL"
     misc_feature    672..686
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     misc_feature    703..717
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    711..724
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     regulatory      739..831
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            973..3372
                     /locus_tag="IE289_RS36640"
                     /old_locus_tag="GCM10010317_075540"
     CDS             973..3372
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378224.1"
                     /locus_tag="IE289_RS36640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075540"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_190172807.1"
                     /transl_table=11
                     /translation="MTIAPADPASATAFAQQERKQVPVETDGPGTTLLRTLTDLTADLP
                     DADPGRVAAATLRGRSAHADDTELRELATEAAAGLISEDPVYSRLAARLLTISIAAEAA
                     SQGVTSFSGSIAAGHREGLIADRTAEFVRLHTARLDALIDTEGDDRFGYFGLRTLHSRY
                     LLRHPITRKVIETPQHFMLRVASGLAEDDTNRALDEVAALYGLMSRLDYLPSSPTLFNS
                     GTRHPQMSSCYLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRSRGSLIRGTNG
                     HSNGIVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHN
                     LNLAHWIPDEFMRRVDTDGQWSLFSPSDVPELVDLWGDEFDTAYRRAEAAGLAKKTIPA
                     RDLYGRMMRTLAQTGNGWMTFKDAANRTANQTAEPGHTVHSSNLCTEILEVTDDGETAV
                     CNLGSVNLGAFVVDGDIDWERLDETVRTAVTFLDRVVDINFYPTEQAGRSNAKWRPVGL
                     GAMGLQDVFFKLRVPFDSPQAKALSTRIAERIMLAAYEASADLAERSGPLPAWEKTRTA
                     RGVLHPDHYGVELTWPERWAALRERIAAVGMRNSLLLAIAPTATIASIAGVYECIEPQV
                     SNLFKRETLSGEFLQVNSYLVDELKKLGVWDAQTREALRESNGSVQGFTWVPQDVRDLY
                     RTAWEIPQRGLIDMAAARTPFLDQAQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLR
                     SRPATRIARAAQAQAQPEKTIPVQAIPDEDAVACSLENPESCEACQ"
     gene            3372..4385
                     /locus_tag="IE289_RS36645"
                     /old_locus_tag="GCM10010317_075550"
     CDS             3372..4385
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966409.1"
                     /locus_tag="IE289_RS36645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075550"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_190172808.1"
                     /transl_table=11
                     /translation="MSSTEKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLH
                     SDVADLAKLSQGEQHMIGRLVAFFATGDSIVSNNLVLTLYKHINSPEARLYLSRQLFEE
                     AVHVQFYLTLLDTYLPDPEDRAAAFDAVESIPSIREKAEFCFKWMDSVEKLDRLETKAD
                     RRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFE
                     VVDTVRKEEPELFDDQLQQQVTDMLKEAVEAELQFARDLCGEGLPGMNTDSMRQYLECV
                     ADQRLQRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGSVGFDEDF"
     misc_feature    4583..4593
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            4776..6857
                     /locus_tag="IE289_RS36650"
                     /old_locus_tag="GCM10010317_075560"
     CDS             4776..6857
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980615.1"
                     /locus_tag="IE289_RS36650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075560"
                     /product="putative Ig domain-containing protein"
                     /protein_id="WP_190172809.1"
                     /transl_table=11
                     /translation="MRETPPSRPARRLRRLLTAAAPALALTVAGLMAAPAANAQPAPTT
                     AKPSRAAQNAKALTAPAAQAVHSTGKAGQKVPTTHLCGAPTAGHAACFAQRRTDIKQKL
                     AAAISPNAAAAVSGLSPANLHSAYNLPSTGGSGLTVAVVDAYNDPNAESDLATYRSQFG
                     LSACTKANGCFKQVSQTGSTSSLPTNDTGWAGEEALDIDMVSAVCPNCNIVLVEANSAT
                     DSDLGTAENEAVTLGAKFVSNSWGGSESSSQTSEDTSYFKHPGVAITVSSGDSAYGAEY
                     PATSQYVTAVGGTALSTSSNTRGWTESVWKTSSTEGTGSGCSAYDAKPSWQTDTGCSKR
                     MEADVSAVADPATGVAVYDTYGGSGWAVYGGTSASSPIIAGVYALAGTPGSSDYPAKYP
                     YSHTSNLYDVTSGNNGSCSPSYFCTAATGYDGPTGWGTPNGTTAFASGTSTGNTVTVTN
                     PGSQSTTTGGSVSLQISASDSAGATLTYSASGLPTGLSISSSTGRISGTASTAGTYSVT
                     VSASDSTGASGSASFTWTVSTSGGGTCTSAQLLGNPGFESGNTTWSASSGVITNSSSEA
                     AHAGSYKAWLDGYGSTHTDTLSQSVTIPSGCKASFTFYLHIDTAETTTSSQYDKLTVTA
                     GSTTLATYSNLNAASGYAQKTFDLSSFAGSTVTLKFSGVEDSSLQTSFVVDDTAVTTS"
     gene            6957..7415
                     /locus_tag="IE289_RS36655"
                     /old_locus_tag="GCM10010317_075570"
     CDS             6957..7415
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072159.1"
                     /locus_tag="IE289_RS36655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075570"
                     /product="hypothetical protein"
                     /protein_id="WP_190172810.1"
                     /transl_table=11
                     /translation="MRRTTHHRILALTALTLLLAGCGTQGGGDAGGSRTVSPSPTTSHP
                     SCDTAPAELGAADTGHTYCLTAGGVLRLTLDGTTSRPWTPVKVSGTGLEATNSGVVLQA
                     GDASSAFKAVSAGTAHLTSSRPLCATAPGKVSCKGIQEWTVTVLVTKS"
     gene            7624..8586
                     /locus_tag="IE289_RS36660"
                     /old_locus_tag="GCM10010317_075580"
     CDS             7624..8586
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378238.1"
                     /locus_tag="IE289_RS36660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075580"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_190172811.1"
                     /transl_table=11
                     /translation="MLKNVAAVLLDGVHPFELGVVCEVFGIDRSDDGLPVYDFAVASAE
                     GPTLSTHAGFSLTTEHGLERLESADLIALPAGNSYVSRSYPPELLDALHRATDRGARVL
                     SVCSGVFVLGAAGLLDGRRCAVHWHHAEELSRQYPKAIVEPDVLYVDEDPVITSAGTAA
                     GIDACLHIVRKEQGPEVANAIARRMVVPPHRDGGQAQYIERPLPRSTCDTVGEVLVWME
                     RHLDREVTVEQLAARAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQELLESSDETMD
                     AIAGRTGFGTAAALRHQFVRSLGTTPQAYRRTFRGPRAA"
     misc_feature    7625..7641
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            complement(8634..10004)
                     /locus_tag="IE289_RS36665"
                     /old_locus_tag="GCM10010317_075590"
     CDS             complement(8634..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="IE289_RS36665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075590"
                     /product="cytochrome P450"
                     /protein_id="WP_099920733.1"
                     /sec_met_domain="p450 (E-value: 6.8e-72, bitscore: 236.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVKPAQPAAPQLPVPPLAGGGVPVLGHGWKLVRDPLGFLAR
                     LRDHGDVVRLKLGPKTVYALTSPALTGAMALSTDFKIDGPLWESLEGLLGKEGVATANG
                     PRHRRQRRTIQPAFRLDIIPEYGPIMEEEARALAERMGSGEPVDCTSESFRVAVRIAAR
                     CLLRGEFMDERAERLSVALATVFRGMYRRMVIPAGPLYRLPLPANRKFDRALADLHLLV
                     DEIVAERRASGQKPDDLLTALLEAKDENGEPIGEQEIHDQVVAILTPGSETVASTIMWL
                     LQVLTEHPEHAARVAEEVKSVVGDRPVAFDDVRKLTYTNNVVVESMRLRPAVWILTRRA
                     VTETELGGYRIPAGADIVYSPFAIQRDPRSYDGHLDFDPDRWLPERAKDVPKHAMSPFS
                     VGNRKCPSDHFSMAQLSLITATVASRWRFEQVSESNDATRVGITLRPYRLLLRALPR"
     gene            complement(10001..11086)
                     /gene="cyc1"
                     /locus_tag="IE289_RS36670"
                     /old_locus_tag="GCM10010317_075600"
     CDS             complement(10001..11086)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384601.1"
                     /locus_tag="IE289_RS36670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075600"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_190172845.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-64, bitscore: 213.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAFSHGTSSTPTVVAVPPALSLPVIESAFPRQLHPYWPRLQENT
                     RSWLREKRLMPADKVDEYADGLCYTDLMAGYYIGAPDEVMQAIADYSAWFFVWDDRHDR
                     DVIHGRPGAWRRLRFQLHAALDSPREHLHHRDPLVAGFADSMVRLYSFLTKKWNARFAR
                     HFHAVIEAYDREFRNRVNGTVPTVEEYLELRRLTFAHWIWTDLLEPSAGCELPTAVRNH
                     FAYRRAALLSQEFAAWYNDLCSLPKEIAGDEFHNLGISLIHHEGLTLEEAIQDTRRRIE
                     ECITEFLDAEKDLNRFSDTLADGTVHGKELSLAVKACLGNMRNWFSSVYWFHHESGRYT
                     VDSWDDRSTPPYVNNEAAGES"
     gene            complement(11396..12046)
                     /gene="def"
                     /locus_tag="IE289_RS36675"
                     /old_locus_tag="GCM10010317_075610"
     CDS             complement(11396..12046)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="IE289_RS36675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075610"
                     /product="peptide deformylase"
                     /protein_id="WP_054228148.1"
                     /transl_table=11
                     /translation="MAQQDTEQQHSGVLPVDDEGFVNDTEDGEEREAAYRERGTSRPIT
                     VVGNPVLHKECKDVTEFGPELDQLVADMFASQRTAEGVGLAANQIGVDLKVFVYDCQDD
                     EGKRHVGVVCNPVLVELPAEQRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPI
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKEALRQMAENEPRYPIVAND"
     gene            complement(12198..13178)
                     /locus_tag="IE289_RS36680"
                     /old_locus_tag="GCM10010317_075620"
     CDS             complement(12198..13178)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="IE289_RS36680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075620"
                     /product="hypothetical protein"
                     /protein_id="WP_060897921.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDREAGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGGAAVSGEPVGMDLGSAAVRLSPEGEAEVVWGRRLDPARVEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTAAGHAYPVFDEIELWAPSPVPTWVVLLEAATEEDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPAPLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            complement(13332..14612)
                     /locus_tag="IE289_RS36685"
                     /old_locus_tag="GCM10010317_075630"
     CDS             complement(13332..14612)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984465.1"
                     /locus_tag="IE289_RS36685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075630"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_190172812.1"
                     /transl_table=11
                     /translation="MSAVGVEIPGYGVVGRAPFTLTLVHAVALLLAVVSLAVVLWHGLD
                     ERGVALAFGILIAVGELTRWSGAEERESAPLAAAGALAYALLGENAGHRTDHGVLEIVA
                     VVVAAALIGCVPHVAQGRGPTADHLTRRVLTVGFAAVCFQPLYNQGRLMGWGGPSYALL
                     LVSLLVLTALCDAVLAAAMAHARTRWPFGPLLRDELRATLGIGSAVCATGAVMSLAVAV
                     VGLWALPVFSLPLLLTQLSVRRYAAVRVTYRQTIASLARATEIAGYTPTGHARRVAALS
                     RAVGRELGLSEPDLTVLEYAALMHDIGQLSLVDPVPAGATSVLSADEQRRIALLGGAVV
                     RQTGVDAEVAVVVERQADPYREQPVTARIVRAVNAYEEMAREAGPGGPLTALEKLRLAT
                     ARDYQPEVVESLARVLLRGTLTLPQAG"
     gene            complement(14609..16096)
                     /locus_tag="IE289_RS36690"
                     /old_locus_tag="GCM10010317_075640"
     CDS             complement(14609..16096)
                     /EC_number="3.1.4.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376704.1"
                     /locus_tag="IE289_RS36690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075640"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_190172813.1"
                     /transl_table=11
                     /translation="MGSIPTWARVYVVCVVLAAVACLAPLPAVHAPWWIVALLAALYAG
                     CERIPFPHSPKGAAARVAERGAPRGLGTFLPVLLAGAFLLPPPAAALVALPGALLARVE
                     QRPRWLRRVWRAAQLAVAVWAASRVHWALGGRDAIALPHFPYALVPAGAAVLTFCLVLT
                     ALDGGILALAERVPVRGAWRGLFSRSLASVAVHGLAGLMMAVLWRSPYGPVAALLVLLP
                     MYVSCWAFAQYHRERAAHQATIRALVQAVDIKDGYTRGHSERVGQASMMIARELGMDDE
                     RVEVLRFAGILHDVGKLGVPTRLLRKDGPLTPEERRIIELHPEYGHEMVRGIGFLGEAR
                     SAILHHHERIDGSGYPYGLVGRQIPEFARVVAVADAFDAMTSTRSYRRARPVPVALEEL
                     ERCAGAQFDPGMVRALVRALDRHGWHPAVTAGVYPPSPEFSTSLEQGGPPSPVSSRTEE
                     HPKDKDPSPTGADGRGADRDPTGVDPPSSGVVGRGRS"
     gene            complement(16252..16554)
                     /gene="rsrA"
                     /locus_tag="IE289_RS36695"
                     /old_locus_tag="GCM10010317_075650"
     CDS             complement(16252..16554)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326971.1"
                     /locus_tag="IE289_RS36695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075650"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_054228151.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDSDCTKFEVHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPTDLRAKVMGRIDLIRSGQTVPEHDVTATPQES"
     gene            complement(16551..17234)
                     /gene="sigR"
                     /locus_tag="IE289_RS36700"
                     /old_locus_tag="GCM10010317_075660"
     CDS             complement(16551..17234)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="IE289_RS36700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075660"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_054228152.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTDHGQAEQPEGQGTSTESSAERTARFERDALEFLD
                     QMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKK
                     QREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKAALQAIPEEFRIAV
                     YLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGLVPAGAGESNEA
                     KGSGS"
     gene            complement(17490..18122)
                     /locus_tag="IE289_RS36705"
                     /old_locus_tag="GCM10010317_075670"
     CDS             complement(17490..18122)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130780.1"
                     /locus_tag="IE289_RS36705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075670"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_190172846.1"
                     /transl_table=11
                     /translation="MDAIETVETDAGTARVTWHRAKKPRLVLAVSHGAGGGVEARDLQA
                     LAAVLPGHGVSVALVEQPWRVAGKKVAPAPKTLDVGWRGLWPTVAKPGLPVVAGGRSAG
                     ARVACRTATELGATAVLALSFPLHPPGRPEKSRADELLGAGVPTLVVQGGNDPFGKPAE
                     FPKGSHDLIEVPYGDHGFAVPKRAPIDQDAALEIITDGVVRWIASLG"
     gene            complement(18211..19026)
                     /locus_tag="IE289_RS36710"
                     /old_locus_tag="GCM10010317_075680"
     CDS             complement(18211..19026)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="IE289_RS36710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075680"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_190172814.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGIFEVEKWEPEETLDPDYNVAPTKDVYAVL
                     DRPLKDAESPKPVRQLRRLKWGLVPSWAKTPEGGARMINARAETVHEKPSYRRAFAARR
                     CIVPADGYYEWVTGSAERDLEVEGKKKRPRKQPYFVLPADGSVFAMAGLYEFWRDRTLP
                     DDHPRAWWVTCSVITTEAETSPLAVAPAEGPYALADIHPRMPLMLTPDRWDAWLDPART
                     DVDGLRELLAPPPAGLMRAYPVSTAVSNVRSNGPELLKELEGPEEGTLF"
     gene            19077..19799
                     /locus_tag="IE289_RS36715"
                     /old_locus_tag="GCM10010317_075690"
     CDS             19077..19799
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480455.1"
                     /locus_tag="IE289_RS36715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075690"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_190172815.1"
                     /transl_table=11
                     /translation="MDSTASTSLASLWDQVSGTQPDPDLWVVIATMVAALAVIVPHGVW
                     RVSRNAITIAHEGGHGLVALLTGRSLSGIRLHSDTSGLTVSRGKPTGLGMILTASAGYT
                     APPLLGLGGAALLGLGRITLLLWLATALLVAMLVMIRNAYGALTVVLTGGTFLVVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCSLLGGSRWLLGL"
     misc_feature    19881..19894
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
ORIGIN
        1 ggcgccgggg cgcagccccg tgccccaggg gcgcggggaa cggcgcgcca agcccccacc
       61 cacccgcagc cgaagaaccg cgccaacaac ccccacgggc cgtcggacac aaatccggcg
      121 gcccgttccc gcgccctgtt gcacactcac cggcatggac atccgcattc gacacgccca
      181 cccccacgaa tacgaccgca tcggcgagat caccgcacag gcctacctcg gcgacggcct
      241 gctcgacttc ggggagagcg acgagtacct cggcgaactg cgggacgtgg cgaaacgggc
      301 caccgccgcg gaggtcctcg tcgccgtgga ccacgaccac gtcctcggcg ccgtgacctt
      361 cgtaccgcgc ggcggcccca tggccgacat agcccgcccc ggcgaagccg agatccgtat
      421 gctcgccgtc gcacgcgagt cccgcggccg aggcgccggc gagaccctcg tccgcgcctg
      481 cgtcgaccac gcacgcgcca ccgccggctg cgcacgcgtc gtgctctcca cccagcgcac
      541 catgcacgcc gcccaccgca tctacgaacg cctcggcttc acccgcaccc ccgaccgcga
      601 ctggaacccg ctcccggacc tcgacgacat cactctcctc acctatgagt tgacactctg
      661 aaaccggcac gacacaacat ctgggggtgt caccgcagcc cggcacaaga tgtatgctca
      721 tgctcgctgt cgccgcaggg gaatccggtg caaatccgga actgtcccgc aacggtgtac
      781 ttgtacgtgt tcgcacatcc gcgcccatgt actcgcgtca gtccgaggac ctgccgacag
      841 cgcgcccggc catccggccc gggtgcatga cgtccgggcc tcgcggaatg ggccggtgga
      901 cgcgacgccg tgtgcgctcg tgagctgccc tgccctccgc caggccccgt gccgagcgag
      961 ggagagcccc aagtgaccat cgcgccagcc gacccggctt cagctaccgc tttcgcacag
     1021 caggagcgga agcaggtccc ggtggagacg gacggtcccg gtaccacgct gctgcgtacc
     1081 ctgaccgacc tcaccgccga cctccccgac gccgaccccg gccgggtcgc cgccgccacg
     1141 ctgcgcggcc ggtccgcgca cgcggacgac acggagctgc gcgagctggc caccgaggcg
     1201 gccgcgggcc tcatctccga ggaccccgtc tactcccggc tggcggccag gctgctgacg
     1261 atcagcatcg cggcggaggc cgcctcgcag ggcgtcacgt ccttctccgg gtcgatcgcc
     1321 gcgggtcacc gcgagggcct gatcgccgac cgcacggcgg agttcgtccg gctgcacacg
     1381 gcccggctgg acgcgctgat cgacaccgaa ggcgacgacc gcttcggcta cttcggcctg
     1441 cgcaccctgc acagccgcta tctgctccgg cacccgatca cccgcaaggt catcgagacc
     1501 ccccagcact tcatgctgcg cgtggcgtcg ggcctggccg aggacgacac gaaccgggcc
     1561 ctggacgagg tcgcggcgct ctacgggctc atgagccgcc tcgactacct cccctcctcc
     1621 cccacgctct tcaactccgg tacgcggcac ccgcagatgt cgtcctgcta cctcctcgac
     1681 tccccgctgg acgagctgga ctccatctac gaccgctacc accaggtggc ccgcctctcg
     1741 aagcacgcgg gcggcatcgg tctttcgtac tcccggatcc gttcgcgcgg ttcgctgatc
     1801 cgcggtacga acgggcactc caacgggatc gtcccgttcc tgaagaccct cgacgcctcg
     1861 gtcgccgcgg tgaaccaggg cggccggcgc aagggcgcgg ccgcggtcta cctggagacc
     1921 tggcactccg acatcgagga gttcctggag ctgcgcgaca acaccggtga ggacgcccgc
     1981 cgtacgcaca acctgaacct cgcgcactgg atcccggacg agttcatgcg ccgggtcgac
     2041 accgacggac agtggtccct cttctcgccc tccgacgtgc ccgagctggt cgacctgtgg
     2101 ggcgacgagt tcgacacggc gtaccgcagg gcggaggcgg ccggtctcgc caagaagacc
     2161 atcccggccc gtgacctcta cggccgcatg atgcgcaccc tcgcgcagac cggcaacggc
     2221 tggatgacct tcaaggacgc cgccaaccgc accgccaacc agacggcgga gccgggccac
     2281 accgtccact cctcgaacct ctgcaccgag atcctggagg tcacagacga cggggagacg
     2341 gcggtctgca acctcggctc ggtcaacctc ggcgccttcg tggtcgacgg ggacatcgac
     2401 tgggagcggc tggacgagac ggtccgtacc gccgtcacct tcctcgaccg tgtcgtcgac
     2461 atcaacttct acccgaccga gcaggccggc cggtcgaacg cgaagtggcg gcccgtcggc
     2521 ctcggcgcga tgggcctgca ggacgtcttc ttcaagctgc gcgtcccctt cgactccccg
     2581 caggccaagg ccctctccac ccggatcgcc gagcggatca tgctcgccgc gtacgaggcc
     2641 tcggccgacc tcgcggagcg cagcggcccg ctcccggcct gggagaagac ccgtacggcc
     2701 cgtggcgtcc tgcatcccga ccactacggc gtggagctga cctggccgga gcgctgggcg
     2761 gccctgcggg aacgtatcgc cgcggtcggc atgcgcaact ccctcctcct cgccatcgcg
     2821 cccaccgcca ccatcgcgtc catcgcgggt gtgtacgagt gcatcgagcc ccaggtgtcc
     2881 aacctgttca agcgcgagac gctctccggt gagttcctcc aggtcaactc ctacctggtg
     2941 gacgagctga agaagctcgg cgtgtgggac gcgcagaccc gcgaggcgct gcgcgagtcc
     3001 aacggttcgg tgcagggctt cacttgggtg ccgcaggacg tccgcgacct gtaccgcacg
     3061 gcctgggaga tcccgcagcg cggcctgatc gacatggccg ccgcccgcac cccgttcctg
     3121 gaccaggcgc agtccctgaa cctcttcctg gagacgccga ccatcggcaa gctctcctcg
     3181 atgtacgcgt acgcctggaa gtcgggactg aagacgacgt actacctgcg ctcccgcccg
     3241 gcgacccgta tcgcccgtgc cgcccaggcg caggcccagc ccgagaagac catccccgtg
     3301 caggcgatcc ccgacgagga cgccgtcgcc tgctcccttg agaaccccga gtcctgcgag
     3361 gcctgccagt aatgagctcc accgaaaaga acctgctcga cccgggcttc gaactcacgc
     3421 tccgccccat gcgctacccc gatttctacg agcgctaccg ggacgccatc aagaacacct
     3481 ggaccgtgga ggaggtcgac ctccactcgg acgtggccga cctggcgaag ctctcgcagg
     3541 gcgagcagca catgatcggc cggctggtcg cgttcttcgc gacgggcgac tcgatcgtgt
     3601 cgaacaacct cgtgctgacc ctctacaagc acatcaactc ccccgaggcg cgcctgtatc
     3661 tctccaggca gctgttcgag gaagcggtcc acgtccagtt ctatctgacc ctgctggaca
     3721 cctaccttcc cgacccggag gaccgcgcgg ccgccttcga cgccgtcgag agcatcccct
     3781 cgatccgcga gaaggccgag ttctgcttca agtggatgga ctcggtggag aagctggacc
     3841 gtctggagac caaggcggac cggcgtcgct tcctgctcaa cctcatctgc ttcgccgcgt
     3901 gcatcgaggg cctcttcttc tacggcgcct tcgcgtacgt ctactggttc cgcagccggg
     3961 gtctgctgca cggtctcgcc accggcacca actgggtgtt ccgcgacgag acgatgcaca
     4021 tgtccttcgc cttcgaggtg gtggacaccg tgcgcaagga ggagccggag ctcttcgacg
     4081 accagctcca gcagcaggtc accgacatgc tgaaagaggc cgtcgaggcc gagctgcagt
     4141 tcgcgcgcga cctgtgcggt gagggtctgc cgggcatgaa caccgactcg atgcgccagt
     4201 acctggagtg cgtggccgac cagcgtctcc agcgcctcgg cttcgccccg gtgtacggct
     4261 ccgagaaccc cttctccttc atggagctcc agggcgtcca ggagctgacc aacttcttcg
     4321 agcgccgccc ctcggcgtac caggtggcgg tggagggctc ggtcggcttc gacgaggact
     4381 tctgacggac gagaacttcc ggcggtacgg ggacttctga cggtacgaca ccggtgatgc
     4441 cgggccgcat gtcgcggccc ggcatcaccg cgtctcgtcc atgggccgtc catgcaccgt
     4501 ccatggaccc cctatggggc ggcaaagttc ttcgggcgtg gctatccggg ggtcatcggc
     4561 cccggctagg ttctggccgt cctgacatgt cacgtacagc ggcacgacag gacgaccgaa
     4621 ttggcatgcc catgtcgcat ccgcacttct ctcacgctac gcgcgtcacg ggcctgccac
     4681 gcaacgccga gaacccccac ttccggctgt ggagccgtgc gcggccctac cccggcccgc
     4741 acggcaccgg cctcaaaccg atggaggcag cacccatgcg tgagacaccc cccagcaggc
     4801 ccgcccggcg actgcgaaga cttctgaccg ccgccgcgcc cgccctcgcc ctcacggtcg
     4861 ccggactcat ggcggccccg gccgcgaacg cgcagccggc gccgaccacc gccaagccct
     4921 cccgggccgc ccagaacgcg aaggccctga ccgccccggc cgcgcaggcc gtgcactcca
     4981 cgggcaaggc gggccagaag gtgccgacca cgcacctgtg cggcgccccg acggccggtc
     5041 acgcggcctg tttcgcgcag cgccgcaccg acatcaagca gaagctggcc gccgcgatct
     5101 cgccgaacgc cgccgccgcg gtgtccggtc tgagcccggc caacctgcac agcgcctaca
     5161 acctgccctc caccggcggc tccggcctga ccgtcgccgt ggtcgacgcg tacaacgacc
     5221 ccaacgcgga gtcggacctc gcgacctacc gttcgcagtt cggcctgtcg gcctgcacca
     5281 aggccaacgg ctgcttcaag caggtcagcc agaccggctc gaccagctcc ctgccgacca
     5341 acgacaccgg ctgggcgggt gaggaagcgc tcgacatcga catggtcagc gcggtctgcc
     5401 cgaactgcaa catcgtcctc gtcgaggcca actcggccac cgactccgac ctcggcaccg
     5461 ccgagaacga ggccgtgacg ctgggcgcga agttcgtctc caacagctgg ggcggctccg
     5521 agtcctcctc gcagaccagc gaggacacct cgtacttcaa gcacccgggc gtcgccatca
     5581 ccgtctcctc cggtgactcc gcctacggcg ccgagtaccc ggccacgtcc cagtacgtga
     5641 cggccgtcgg cggcaccgcg ctgtccacca gctccaacac ccgcggctgg accgagtccg
     5701 tgtggaagac gagcagcacc gagggcaccg ggtccggctg ctccgcgtac gacgcgaagc
     5761 cgagctggca gaccgacacc ggctgctcca agcgcatgga ggccgacgtc tccgcggtcg
     5821 ccgaccccgc caccggcgtg gccgtctacg acacctacgg cggctccggc tgggcggtct
     5881 acggcggtac gagtgcctcc tcgccgatca tcgcgggtgt gtacgccctc gcgggcaccc
     5941 cgggctccag cgactacccg gcgaagtacc cgtactccca cacctcgaac ctgtacgacg
     6001 tgaccagcgg caacaacggc tcctgctcgc cctcgtactt ctgcaccgcg gccaccggct
     6061 acgacggccc gaccggctgg ggcaccccga acggcaccac cgccttcgcc tcgggcacca
     6121 gcaccggcaa cacggtgacc gtcaccaacc cgggcagcca gtccaccacc accggcggtt
     6181 cggtcagcct gcagatctcg gcgagcgaca gcgcgggcgc gaccctcacc tacagcgcga
     6241 gcggtctgcc gaccggtctt tcgatcagca gctccaccgg tcggatctcg ggcaccgcga
     6301 gcacggccgg tacgtacagc gtcaccgtct ccgcctccga cagcacgggt gcctccggct
     6361 ccgcctcctt cacctggacc gtcagcacct ccggcggcgg cacctgcacc tcggcgcagc
     6421 tgctcggcaa cccgggcttc gagtcgggca acaccacctg gagcgccagc agcggcgtga
     6481 tcaccaactc cagcagtgag gcggcgcacg ccggttcgta caaggcatgg ctggacggct
     6541 acggctcgac gcacaccgac acgctctccc agtcggtgac gatcccgtcc ggctgcaagg
     6601 ccagcttcac cttctacctg cacatcgaca ccgcggagac caccacaagc agccagtacg
     6661 acaagctgac ggtcaccgcc ggatcgacca ccctggcgac gtactcgaac ctcaacgccg
     6721 cctccggcta cgcccagaag accttcgacc tgtcctcgtt cgccgggtcc accgtcaccc
     6781 tgaagttcag cggtgtcgag gactcctcgc tccagaccag cttcgtcgtc gacgacaccg
     6841 ccgtcacgac cagctgacca gtggggccct ggccggcgtc gcggccaggg ccctgtgtcc
     6901 ctgtgtggat cctgatgcgg gggtggcacg tccaagcgac aaggaggtgc caccccatgc
     6961 gccgtacgac ccaccatcgg atcctcgccc tcacggccct gacgctgctc ctcgcgggct
     7021 gcggcacaca gggcggcggt gacgcgggcg gcagccgcac cgtgtcgccg tcccccacga
     7081 cgagccaccc aagctgtgac acggctcccg cggagctcgg cgcagccgac accggccaca
     7141 cgtactgcct cacggccggc ggcgtactcc gcctcaccct ggacggcacc accagtcggc
     7201 cgtggacacc cgtcaaggtc agcggcaccg ggctagaagc caccaacagc ggcgtcgtcc
     7261 tccaggcggg cgacgcgagc tccgccttca aggcggtctc ggcgggaacc gcccacctca
     7321 cctcgtcccg gccgctctgt gcgaccgccc cgggcaaggt gtcgtgcaag ggcattcagg
     7381 agtggacggt cacggtgctg gtcacgaagt cctagctgac ggtcgatgcg ccgctcgcgg
     7441 gccgcgccga tcagcgcggg cagggccacg accacgaaga gcgcgaggac ggtcaggatt
     7501 ccggcggtgg tgtccatgag tgtcttcatg aacaccactg tcgtaccgct cgcccttcgg
     7561 cgtcagtggc aggactgccg tacaccctcg atttcctgcc actgacgagg cacactggcg
     7621 gacatgctga aaaacgtggc cgcggtcctg ctcgacggtg tgcacccctt cgaactcggg
     7681 gtcgtctgcg aggtgttcgg catcgaccgc agcgacgacg gcctgcccgt ctacgacttc
     7741 gcggtcgcct ccgccgaggg cccgaccctg agcacccacg cggggttctc gctgaccacg
     7801 gagcacggcc tggagcggct ggagagcgcc gacctcatcg ctctccccgc cgggaactcc
     7861 tatgtgtccc ggtcctatcc gcccgaactg ctcgacgccc tgcaccgcgc cacggaccgc
     7921 ggcgcccggg tgctcagcgt ctgctccggt gtcttcgtgc tcggcgcggc cgggctcctc
     7981 gacgggcggc gctgcgccgt gcactggcac cacgccgagg agctctcccg gcagtacccg
     8041 aaggcgatcg tcgaaccgga cgtgctgtac gtggacgagg acccggtgat cacctcggcc
     8101 ggcaccgccg ccggaatcga cgcctgtctg cacatcgtcc gcaaggaaca gggccccgag
     8161 gtcgccaacg ccatcgcccg ccggatggtg gtgcccccgc accgggacgg cgggcaggcc
     8221 cagtacatcg agcgcccgct gccccgctcc acctgcgaca cggtcggcga ggtgctggtg
     8281 tggatggagc gccacctcga ccgggaggtg accgtcgagc agctcgcggc ccgcgcccac
     8341 atgtccccgc gcaccttcgc acgccgcttc cagcaggaga ccggcaccac cccgtaccgc
     8401 tggatcctgc gccagagggt gctgctggca caggagttgc tggagtcgtc ggacgagacg
     8461 atggacgcca tcgcgggccg caccgggttc ggcaccgcgg ccgcgctgcg ccaccagttc
     8521 gtccggagcc tggggacgac cccgcaggcg taccggcgca cgttcagggg cccgcgggcc
     8581 gcctgaacgc gcaccgggac ggacacgggg tcaccgcgga cgatgccgca cggtcaccgc
     8641 ggcagggccc tcagcagcag ccggtacgga cgcagggtga tgccgacgcg ggtcgcgtca
     8701 ttggactcgg agacctgctc gaaccgccac cgggacgcca ccgtcgccgt gatcaggctg
     8761 agctgcgcca tcgagaagtg gtcgctcggg cacttccggt tgcccacact gaaggggctc
     8821 atggcgtgct tcgggacgtc cttggcgcgt tccggaagcc agcggtcggg gtcgaaatcc
     8881 agatgcccgt cgtacgagcg cggatcacgc tggatggcga acgggctgta gacgatgtcg
     8941 gcaccggccg gtatccgata gccgccgagt tcggtttcgg tcaccgcccg ccgggtcaaa
     9001 atccatacgg cggggcgcag ccgcatcgac tcgacgacga cattgttggt gtacgtcagc
     9061 ttccggacgt cgtcgaatgc gacgggccgg tccccgacga cggatttgac ctcctcggcc
     9121 acccgagcgg cgtgttccgg gtgttcggtg aggacttgca gcagccacat gatcgtggac
     9181 gccacggttt cgctgccggg cgtgagtatc gctacgactt ggtcgtggat ctcctgttcg
     9241 ccgatcggct cgccgttctc gtccttcgct tccagcaatg ccgtcagcaa atcgtccggc
     9301 ttttgaccgg atgcgcggcg ctcggcgacg atctcgtcga cgaggagatg caaatcggcc
     9361 aatgcacggt cgaatttacg gttggccgga agcggcagcc gatagagcgg gcccgccggg
     9421 atcaccatgc gccggtacat accgcggaac acggtggcga gcgcgacgct cagccgctcg
     9481 gcgcgctcgt ccatgaactc gccgcgcagc agacagcggg ccgcgatgcg cacggcgacg
     9541 cggaacgact cggaggtgca gtcgacgggc tcgcccgacc ccatgcgctc ggcaagcgca
     9601 cgcgcctcct cctccatgat cggtccgtac tcggggatga tgtcgagccg gaacgcgggc
     9661 tggatggtgc ggcgctggcg acggtgcctc ggcccgttcg cggtggcgac gccctccttg
     9721 ccgagcaggc cttccaggga ctcccagagg ggtccgtcga tcttgaagtc ggtgctgagc
     9781 gccatcgctc cggtgagggc cggcgaggtg agcgcgtaca ccgtcttggg gcccagcttg
     9841 agccgtacga cgtcgccgtg gtcgcggagc cgggcgagga agcccagcgg gtcgcggacc
     9901 agtttccagc cgtggcccag gacgggtacg ccgcccccgg ccaggggtgg gacgggcagc
     9961 tgtggtgccg cgggttgcgc gggcttcacg gactcgacgg tcatgactca cctgccgctt
    10021 cgttgttgac gtacgggggt gtggagcggt cgtcccagct gtcgacggtg taccggccgg
    10081 actcgtggtg gaaccagtac acggagctga accagttccg catattgccg aggcacgctt
    10141 tcacggcgag gctcaattcc ttgccgtgca cggtgccgtc cgcgagggtg tcggagaacc
    10201 ggttgaggtc cttttccgcg tcgaggaatt cggtgatgca ttcctcgatc cgccgccggg
    10261 tgtcctggat cgcttcttcg agtgtcagcc cctcgtgatg gatgaggctg attccgagat
    10321 tgtggaactc gtcgcccgcg atttctttcg ggagcgagca gaggtcgttg taccaggcgg
    10381 cgaattcctg gctcagcagc gccgcccgcc gatatgcgaa atggttccgc acggcggtgg
    10441 gaagttcaca gcccgcgctc ggctccagaa ggtcggtcca gatccagtgc gcgaaggtga
    10501 gccgccgcag ttccagatat tcctcgaccg tgggcacggt gccgttgaca cggttgcgga
    10561 attcccggtc gtacgcctcg atcaccgcgt ggaaatgccg ggcgaagcgc gcgttccact
    10621 tcttggtcag gaacgagtac aggcgcacca tgctgtccgc gaaccccgcg accaggggat
    10681 cccggtggtg caggtgctcc ctgggggagt cgagagccgc gtgcagctgg aacctgagcc
    10741 tccgccaggc gccgggcctg ccgtggatga catcgcggtc gtggcggtcg tcccagacga
    10801 agaaccacgc gctgtagtcc gctatcgcct gcatgacctc gtcgggagcg ccaatgtagt
    10861 agcccgccat caggtccgta tagcaaaggc cgtcggcata ttcgtcgacc ttgtccgccg
    10921 gcatgaggcg tttttccctc agccacgaac gtgtgttctc ctggagcctc ggccaatacg
    10981 ggtgcagttg acggggaaac gcggactcga tcaccgggag agagagcgcc ggtggaaccg
    11041 cgaccacggt cggtgtcgat gaagtgccgt gtgagaatgc atgcacgaac aaacccctct
    11101 cagccgccag ttgacgctgc gcccctcccg ctgtgccggg cgtgcgccgt tgcgtatccc
    11161 cgcacttccc attcagcacc acaactgacc gttctgggaa cggatttact ccactcgcta
    11221 ccccacagtg ctgagaatct ccccttgtgt gactgaatat ggatcactag aggagcacgg
    11281 gggatcgaat gtgcgacgca catacgaacg gcgcctggtc agggagctcc ccctgaccag
    11341 acgccgctcg ggccgacccg cgcgtgcgcg cgagccccaa ctgtcctgcc gcgactcagt
    11401 cgttcgcgac gatcgggtag cggggctcgt tctcggccat ctgccgcagg gcttccttgc
    11461 gctcgcgctt ggagagccgg tcgatgtaga ggtagccgta caggtggtcg gtctcgtgct
    11521 ggaggcagcg cgcgaagtag ccggtgccac gcaccttgat cgggttgccc ttctcgtcct
    11581 gcccggtgac ctccgcgtag tcggggcggg ccagcggcgc gtacgcggtc ggcaccgaga
    11641 ggcagccctc gttgctgtcg tcgaggcggc gctgctcggc gggcagctcg acgaggacgg
    11701 ggttgcagac gacaccgacg tgccgcttgc cctcgtcgtc ctggcagtcg tagacgaaga
    11761 ccttcaggtc gacgccgatc tggttggccg ccaggcccac gccctcggcg gtgcgctggc
    11821 tggcgaacat gtcggcgacc agctggtcga gctcgggccc gaactcggtg acgtccttgc
    11881 actccttgtg cagcaccggg ttgccgacga ccgtgatcgg ccgcgaggta ccgcgctcac
    11941 ggtaggccgc ctcgcgctcc tcaccgtcct cggtgtcgtt gacgaagccc tcgtcgtcca
    12001 cggggagcac tccagagtgc tgctgctcgg tgtcctgctg cgccatgacc gacgtacgcc
    12061 ttcctcgaaa ccaggggtgt ggtgctcata cagggtacgg gggtggcacc ccgcgagggc
    12121 gcgggactgt gttgatctgc ggctccgccg cgtgggcgcg acaagccccc accggcccgc
    12181 ggtgaacccg caagcgctca gcagacctct tcgagatccc gccagtcccg ggagtcgggg
    12241 ctgtccgcga cccacccgtc cagcagcccc ctgaccagcg gagccggcgc agccaccccg
    12301 cactcccgct ccggcaccca cagctgcccg tcggtgcggt gaccgagcgg ccccggatgc
    12361 ccgggctcgc tgtggtcgtg cgggtcgaga tgctcaccgt cgccctcgtc ggacggcatc
    12421 cgcgactcgg aacacatccg gcacagcagc cgtacggacg aggaccagtc ctccgcggcg
    12481 aagccggcgt ccgccgcgag ctgctccagg gcgtcccggt cctcctcggt ggcggcctcc
    12541 aggaggacca cccaggtggg caccggagag ggcgcccaca gctcgatctc gtcgaagacc
    12601 ggataggcgt gcccggcggc ggtcgtccgc tccccgtgcg gcacaccgtc gtgcagaacg
    12661 acctcgcccc agcgccgccc agaggacggc agcggaatgg acaggacctc cacccgggcc
    12721 ggatcgagcc tgcgccccca cacgacctcg gcctcgccct ccggcgacag ccgtacggcc
    12781 gcactgccga ggtccatgcc caccggttcc ccggagacgg cggccccgcc gggcacccgc
    12841 agcccgtacg cctgccaggc acggcgggcc agcggccagt cctgcagggc ggtggcggcg
    12901 atcccgacgt tccaccagtc gggggcgccc gcctcccggt cgagaagtgc gacggccctg
    12961 aggcccgcgg cccgcgcctg ctcccagtcg tgccggaact tgtgcagcag ggccaggttg
    13021 aaccaggact ccgacagcca gggctccagg tccgcggcgc gcgtcagcag cgctcccgcg
    13081 tcctcgtacc ggccgtcgcc gatcagcgtg aacgcgcgat cggtggcctg ccgccatgag
    13141 gcggagggcc ggtgccgtcc cttgccgaag atcctcacga ttcccgcctg ccagttcctt
    13201 gcgtttcccg cctgccggtc ccttgaagag tttcttgaag acagcgcagc cccgggccga
    13261 cccgtgcccc cgaacaccct cttcctcgca tccaaccacg gaccgttgga cgggcgctca
    13321 ttacccatgg gttacccagc ctggggcagg gtaagggtgc cccgcaacag gaccctggcc
    13381 agcgactcca ctacctcggg ctgatagtcg cgggcggtgg ccaggcgcag cttctccagg
    13441 gcggtgaggg gccctcccgg gcctgcttcc cttgccatct cctcgtacgc gttgacggcc
    13501 cgcacgatcc gtgccgtgac cggctgctcc cggtacggat cggcctgccg ctccacgacc
    13561 acggcgacct cggcgtccac gccggtctgg cgtacgacgg cgccgccgag gagggctatg
    13621 cgccgctgct cgtcggcgga gagcacggag gtggcgccgg ccggcaccgg gtcgacgagg
    13681 ctgagctgtc cgatgtcgtg catgagcgcc gcgtactcca ggacggtcag atcgggctcg
    13741 gacaggccca gctcacggcc gacggcccgg ctgagcgcgg cgacccgccg ggcgtgcccg
    13801 gtgggggtgt acccggcgat ctcggtcgcc ctcgcgagtg aggcgatcgt ctgccgatag
    13861 gtgacgcgca cggcggcgta ccgccggacg gagagctggg tgagcagcag gggcagcgag
    13921 aacacgggca gcgcccacag cccgacgacc gccaccgcga gcgacatcac ggccccggtc
    13981 gcgcagaccg ccgacccgat gccgagggtg gcccgcagct cgtcccgcag cagcggtccg
    14041 aagggccagc gggtccgggc gtgcgccatc gccgccgcga gcacggcgtc gcacagcgcg
    14101 gtgagcacca gcagggagac cagcagcagg gcgtacgaag ggccgcccca gcccatcaac
    14161 cttccctggt tgtagagggg ttggaagcag acggcggcga agccgacggt gaggacgcgc
    14221 cgggtgaggt ggtcggcggt gggcccgcgg ccctgggcga cgtgcggtac gcagccgatg
    14281 agggccgcgg ccacgacgac ggcgacgatc tcgaggacgc cgtggtcggt gcggtgtccg
    14341 gcgttctcgc cgagcagcgc gtacgcgagg gctccggcgg cggcgagggg cgccgactcc
    14401 cgctcctcgg ccccgctcca gcgggtcagc tcccccacag cgatgaggat cccgaaggcg
    14461 agcgcgacgc ctcgttcgtc gagaccgtgc cagaggacga cggccagcga gacaacggcg
    14521 aggagcaggg cgaccgcgtg aacgagggtg agggtgaacg gggcccgccc gacgaccccg
    14581 tacccgggaa tctccacccc gacggcactc atgaccgccc ccgcccgacg acgccgctcg
    14641 acggagggtc gacacctgtc gggtcccggt ccgcgccacg cccgtcggcg cccgtcgggg
    14701 aagggtcttt gtctttcggg tgctcctctg tccgactgga aacgggtgat gggggtcccc
    14761 cctgttcgag cgaagtcgag aactcggggg agggcgggta gacccccgcg gtgaccgcag
    14821 gatgccaccc gtgtcggtcc agcgctcgca ccagggcccg taccatcccc ggatcgaact
    14881 gcgcccccgc acaccgttcc agttcctcca gcgccaccgg caccggccgg gcccgccggt
    14941 aggaccgggt cgacgtcatc gcgtcgaacg cgtcggcgac ggccaccacg cgcgcgaact
    15001 ccgggatctg gcgtcccacc agcccgtacg ggtacccgct cccgtcgatc cgctcatggt
    15061 ggtgcaggat cgccgaccgc gcctcgccga gaaagccgat gccgcgcacc atctcgtgcc
    15121 cgtactcggg atgcagctcg atgatccgcc gttcctccgg cgtcagcggc ccgtccttgc
    15181 gcaggagccg cgtggggacg cccagcttcc ccacgtcgtg caggatcccg gcgaaccgca
    15241 gcacttcgac gcgctcgtcg tccatgccca gctcacgggc gatcatcatg gacgcctgcc
    15301 cgacccgctc actgtgcccg cgcgtgtacc cgtccttgat gtcgacggcc tgcacgaggg
    15361 cccggatggt ggcctggtgg gcggcccgct cccggtggta ctgggcgaac gcccagcagg
    15421 acacgtacat cggcagcagg acgagcaacg cggcgacggg accgtacgga ctgcgccaca
    15481 gcaccgccat catcagcccg gcgagcccgt gcacggcgac ggaggcgagg gagcgcgaga
    15541 agagcccgcg ccaggcaccc cgcaccggca cccgctcggc gagcgccagg attccgccgt
    15601 cgagcgcggt caggaccagg cagaaggtga gcaccgcggc cccggcgggc acgagcgcgt
    15661 acgggaagtg gggcagggcg atcgcgtccc ggccgcccag cgcccagtgc acccgggacg
    15721 ccgcccagac cgcgacggcg agctgggccg cgcgccagac ccggcgcagc caccgcggcc
    15781 gctgctccac acgggcgagc agcgcccccg gcagcgccac gagcgcggcg gccggcggcg
    15841 gcagcagaaa agccccagcg agcagcacgg gcaggaaggt gcccagccct ctgggggcgc
    15901 cccgctcggc gacgcgggcg gcggcaccct tggggctgtg cgggaagggg atccgctcgc
    15961 agccggcgta cagcgcggcg agcagggcga cgatccacca gggtgcgtga acggcgggca
    16021 gcggagccag gcaggccacc gcggccagga cgacacagac gacgtagaca cgggcccacg
    16081 tcggaatcga ccccatcgcc tcgttccctc ccccggacgt cccctgcccc ggtcaggctc
    16141 cggagcctag ggcggtgggg acggtacggg ggcggcaatg gccgaatccg cgggctcgga
    16201 gcccgcggat tagcacgttc gggtgataac cggacgatct ccccggggag ttcaggactc
    16261 ctggggcgtc gcggtgacgt cgtgctcggg cacggtctga ccggaccgga tcaggtcgat
    16321 gcgacccatg accttggcgc gcagatcggt cggcacgtcg tcctggccgc agcaccgctt
    16381 gaccagcttc ttcacggcct gctcgagtcc gtacttctcg agacacgggg agcactcctc
    16441 gaagtgcacc tcgaacttgg tgcagtccga gtccggcatc tcatggtcga ggaactcgta
    16501 caggtggtcg agtacctcac tgcaatccgt ctcgtgcggc tctccgcagc tcatgagccc
    16561 gagcctttcg cttcgttcga ctctccggcg ccggccggga ccagcccgcg gtcacgggcg
    16621 tagtcctcga gcatgccgcg cagttggcga cggccccggt gcagccggga catcaccgta
    16681 ccgatgggtg tccccatgat gtccgcgatc tccttgtacg caaagccttc tacatcagcg
    16741 agatagaccg cgatgcggaa ttcctcgggg atcgcctgca gcgcagcctt gacgtccgag
    16801 tcgggcaggt ggtcgagcgc ctgcgactcc gcggagcgca gaccggtcga catgtgcgac
    16861 tcggcacgcg cgagctgcca gtcctcgatc tcctcggccg cactgcgctg gggttcgcgc
    16921 tgcttcttgc ggtacgagtt gatgaaggtg ttggtgagaa tgcgatacag ccaagccttg
    16981 aggttggtgc cctcgcggaa ctggtggaag gacgcgtacg ccttcgcgta cgtctcctgc
    17041 accaggtcct cggcgtcggc cgggttgcgc gtcatgcgca gggcggccga gtacatctgg
    17101 tcgaggaatt cgagcgcgtc ccgctcgaag cgcgcggtgc gctcggcgga cgactccgtg
    17161 ctcgtgccct ggccctcggg ctgctccgcc tggccgtgat cggtccctgc gtcggtccca
    17221 gtgaccggac ccacctcctc cagcgacgtg gcaggaccga aaccggtccc actcgaatcg
    17281 gaggatagac gaacatccac acccgccgcc gctcgaacgg gggcggtctt cgccgcgtgc
    17341 agcaccgtcc agtccagctc agggctactg ctgcggttcg ggcagatggt cgaacccatg
    17401 cggcggactt cctctcgttc gaacggttca gcacgctccg tgctgtctgc tcgacacaac
    17461 agtggtccac cgcccgacat tcccgtgcgt cacccgagtg acgcgatcca cctcacgacg
    17521 ccgtcggtga tgatctccag ggccgcgtcc tggtcgatcg gtgcccgttt cggcacggcg
    17581 aagccatgat cgccgtacgg cacctcgatc agatcgtgcg agcccttcgg gaactccgcg
    17641 ggcttgccga acgggtcgtt gccgccctgg acgacgaggg tgggcacccc ggcgccgagg
    17701 agttcgtcgg cgcgggactt ctcgggcctg ccgggcggat gcaacgggaa actgagggcg
    17761 aggacggcgg tggcgccgag ttccgtcgcc gtacggcagg cgacgcgggc tccggcgctg
    17821 cgcccgcccg cgaccaccgg cagtccgggc ttcgcgaccg tgggccacag gccccgccat
    17881 cccacgtcca gggtcttggg cgcgggcgcc accttcttcc cggccacccg ccagggctgc
    17941 tcgacgagcg cgacgctcac gccgtgcccg ggcagcaccg ccgccagcgc ctggagatcg
    18001 cgcgcctcga caccgccgcc cgcgccgtga ctcacagcga gcacgaggcg tggcttcttg
    18061 gcccggtgcc acgtgacgcg ggctgtaccg gcgtccgtct cgaccgtctc gatcgcgtcc
    18121 atgatctccg tcacgtcgga cttccatggt ctctgtcacg gaaggcttcc atggtctctg
    18181 tcatggaagg cttccatgac ctccgtcacg tcagaagagt gtgccctctt cggggccttc
    18241 cagctccttc agcagctccg gtccgttgct gcggacgttg ctgacggccg tggagacggg
    18301 ataggcacgc atcagcccgg cgggcggcgg cgcgagcagc tcgcgcaggc cgtcgacgtc
    18361 cgtacgggcc gggtcgagcc aggcgtccca gcggtccgga gtgagcatca ggggcatccg
    18421 ggggtggatg tcggcgaggg cgtacggccc ctcggcgggc gcgaccgcga gcggcgaggt
    18481 ctccgcctcg gtcgtgatca ccgagcacgt cacccaccag gcccgggggt ggtcgtcggg
    18541 gagcgtccgg tcgcgccaga actcgtacag tcctgccatc gcgaagaccg agccgtccgc
    18601 gggcagcacg aagtacggct gcttgcgcgg ccgcttcttc ttgccctcga cctcgagatc
    18661 gcgctcggcg gacccggtga cccactcgta gtagccgtcg gcgggaacga tgcaacgccg
    18721 ggcggcgaag gcacggcggt acgagggctt ctcgtgcacg gtctccgcgc gggcgttgat
    18781 catccgggcg ccgccctcgg gcgtcttggc ccaggacggg acgagccccc acttgagcct
    18841 gcgcagctgg cgaaccggct tcgggctctc cgcgtcctta agggggcggt cgaggacggc
    18901 atatacgtcc ttggtcggag ccacgttgta gtcggggtcc aaggtctcct cgggctccca
    18961 cttctcgacc tcaaagattc ctgcgagatc ctcgggccta cgactcgctg cataccgtcc
    19021 gcacatacgt gccacactgc cagattccgc gacaccagag ggagccaccg cagacaatgg
    19081 acagcaccgc atccacctcg ctggcctcgc tgtgggacca ggtctccggc acccagccgg
    19141 accccgatct gtgggtggtg atagccacca tggtcgccgc tctcgcggtg atcgtcccgc
    19201 acggcgtctg gcgtgtctcc cgcaacgcca tcaccatcgc gcacgagggc ggccacgggc
    19261 tggtggcgct gctgaccggg cggagcctca gtggtatccg gctgcactcc gacaccagcg
    19321 gcctcaccgt cagccgcggc aaacccaccg gcctcggcat gatcctcacc gcgtcggccg
    19381 gctacaccgc tcccccgctg ctcggcctcg gcggcgccgc gctgctgggc ctgggccgca
    19441 tcaccctgct gctgtggctg gccacggccc tgctcgtcgc gatgctggtg atgatccgca
    19501 acgcctacgg ggcgctcacg gtggtcctca ccggcggcac gttcctggtg gtgtcctggc
    19561 tcgccggacc ccaggtacag gcggccttcg cgtacgccgt ggtgtggttc ctgctgctcg
    19621 gcggcgtccg tccggccttc gagctccagg ccaagcgcag ccggggcggc gccggcgact
    19681 ccgacgccga ccagctctcc cgcctcaccc acgtcccggc ggggctgtgg ctgttcctgt
    19741 tccacgcggt gtccctgtgc tctctgctgg gcggcagccg ctggctgctg gggctttgag
    19801 tgcgagggcg tcgagcgcga gggcgtcgag cgcgggggcg ttgaggcacc cctgaaactt
    19861 tcgctcacat tccgtcactt ttgatcaaga tctaccccca cccccaccca ctaaagtggg
    19921 cgcatgaccg cgaaccccgc ccacaccgcc ctctggcccg ccccgcacgc gagcggagcc
    19981 gtcgacgcga cggtccacgt gccggggtcc aagtcggtca ccaaccgcgc cctggtcctc
    20041 gccgcgctcg cctcggagcc gggctggctg cgccgcccgc tgcgctcccg ggacacgctg
    20101 ctgatggcgg gcgcgctgcg cgcgatgggc gtcggtatcg aggagacggt ggcgtccagc
    20161 tccacggtcg ccgcgggccc ggacgcctcc ggcgaggcct ggcgggtcat cccctcgggt
    20221 ctccagggtc cggccacggt cgacgtcggc aacgccggca ccgtgatgcg cttcctgccc
    20281 ccggtcgccg ccctcgcgga cggccccatc cgcttcgacg gcgacccccg gtcgtacgag
    20341 cgcccgctga acggtgtgat cgacgcgctg cgtctgctcg gcgcccgcat cgacgacgac
    20401 ggccgcggcg cgctgccgct gaccgtgcac ggcggcggcg ccctggacgg cggcccggtg
    20461 gagatcgacg cgtcctcgtc gtcccagttc gtgagcgccc tcctcctgtc cggcccccgc
    20521 ttcaaccagg gggtggaggt ccgtcacatc ggctcgacgc tgccctcgat gccgcacatc
    20581 cggatgacgg tcgacatgtt gcgcgcggtc ggcgcgcagg tggacacccc ggagtcgggc
    20641 ggcgagccca acgtctggcg ggtcacgccc ggcgcgctgc tcggccgcga cctgatcatc
    20701 gagccggacc tgtcgaacgc ccagccgttc ctggcggcgg ccctggtgac cggcggcacg
    20761 gtcgtcgtcc ccgactggcc cgcccacacc acccagcccg gtgaccggct gcgggagatc
    20821 ttcaccgaaa tgggcggttc ctgcgaactg aacgacagcg gtctggagtt caccggttcg
    20881 ggtgccatcc acggcatcga cgtggacctg agcgaggtcg gcgagctgac cccaggcatc
    20941 gcggcggtcg cggccctcgc cgactccccg tccaccctgc ggggcgtggc ccatctgcgc
    21001 ctgcacgaga cggaccggct ggccgcgctc accaaggaga tcaacgaact cggcggtgac
    21061 gtcaccgaga ccgccgacgg cctgca
//
