LOCUS       NZ_BMUQ01000019        21047 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence19, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000019
VERSION     NZ_BMUQ01000019.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 226249)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 104566
            Orig. end                         :: 125613
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21047
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21047
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21047
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11047](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11047)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(11..26)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.93"
                     /tool="antismash"
     gene            complement(453..1241)
                     /locus_tag="IE289_RS36455"
                     /old_locus_tag="GCM10010317_075160"
     CDS             complement(453..1241)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984417.1"
                     /locus_tag="IE289_RS36455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075160"
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="WP_190172791.1"
                     /transl_table=11
                     /translation="MTVGTGIDSDEIHGNGTDWHAWQKSWDRQQEWYMPDREERFRVML
                     DMVEALCGPEPRVLDLACGTGTITARLLDRFPKATSTGVDLDPALLTIAEGTFAGDDRV
                     SLVTADLKDPHWATRLPYDSYDAVLTATALHWLHSEPLAVLYGQVAELVRDGGVFMNAD
                     HMIDESTPRINEAERAQRHARMDQARARGVLDWAAWWELAAQDPALAAPTARRFEIYGE
                     HADGDMPSVDWHTRVLREKGFGEARAVWRSPSDALVLAVK"
     gene            1354..1983
                     /locus_tag="IE289_RS36460"
                     /old_locus_tag="GCM10010317_075170"
     CDS             1354..1983
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="IE289_RS36460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075170"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_099920707.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPTRGKDSLTSVEAVRDLFGGNSSAARR
                     ATDADVTRFRSVRARLRAVFEAADGGDETLSVDLLNSLLLEFPVSPQISGHDHRDDDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSESTGLAAPSAQRTTASGER"
     gene            complement(1887..2321)
                     /gene="sodX"
                     /locus_tag="IE289_RS36465"
                     /old_locus_tag="GCM10010317_075180"
     CDS             complement(1887..2321)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="IE289_RS36465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075180"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_075028985.1"
                     /transl_table=11
                     /translation="MPELSQETERGRAVLPFGAAEVTGPSMVPTLQHGDRLVVQYGARV
                     RPGDVVVLRHPFQQDLLVVKRIAERREGGWWVLGDNAYAGGDSTDYGTVPEDLVLGKVR
                     FRYRPHLPGQRSPLAVVRWALGAARPVLSDRSASRRLRAR"
     gene            2466..2861
                     /gene="sodN"
                     /locus_tag="IE289_RS36470"
                     /old_locus_tag="GCM10010317_075190"
     CDS             2466..2861
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="IE289_RS36470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075190"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_004983535.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAGN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKA
                     STDPATGQKALDYIAQIDKIFWETKKA"
     gene            complement(3068..4021)
                     /locus_tag="IE289_RS36475"
                     /old_locus_tag="GCM10010317_075200"
     CDS             complement(3068..4021)
                     /NRPS_PKS="Domain: PKS_ER (14-313). E-value: 2.9e-42.
                     Score: 136.8. Matches aSDomain:
                     nrpspksdomains_IE289_RS36475_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056099.1"
                     /locus_tag="IE289_RS36475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075200"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_190172792.1"
                     /sec_met_domain="ADH_N (E-value: 1.2e-09, bitscore: 31.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.1e-14, bitscore:
                     48.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAQITSYGDAADVLRINDVDRPAPGAGEVLVRVEASSVNGHDV
                     IVRSGEMKIVSGRRFPLGTGLDFAGVVTGSGTGVEGLRVGDRVWGTVHPRQRHTIGGAA
                     EYVVVPADRLAPAPAALSAADAASLVVAGATALIAVRDTVRLAPGEKVLVRGAAGGVGT
                     AAVQLAHALGCHVTALARARHAPALTDLGADEVLDHGSTTSDRIGPFDVIVDTVGTELN
                     CYRSRLAKGGRMVTVGLSAPALAAIAASSVYGARRVRTFSANPDATVLRALADHVTSGA
                     LRPVVNGVYPLADIAAAHQAFERGGVVGKHVVAVSE"
     aSDomain        complement(3083..3979)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS36475_PKS_ER.1"
                     /evalue="2.90E-42"
                     /label="IE289_RS36475_PKS_ER.1"
                     /locus_tag="IE289_RS36475"
                     /protein_end="313"
                     /protein_start="14"
                     /score="136.8"
                     /tool="antismash"
                     /translation="VLRINDVDRPAPGAGEVLVRVEASSVNGHDVIVRSGEMKIVSGRR
                     FPLGTGLDFAGVVTGSGTGVEGLRVGDRVWGTVHPRQRHTIGGAAEYVVVPADRLAPAP
                     AALSAADAASLVVAGATALIAVRDTVRLAPGEKVLVRGAAGGVGTAAVQLAHALGCHVT
                     ALARARHAPALTDLGADEVLDHGSTTSDRIGPFDVIVDTVGTELNCYRSRLAKGGRMVT
                     VGLSAPALAAIAASSVYGARRVRTFSANPDATVLRALADHVTSGALRPVVNGVYPLADI
                     AAAHQAFERGGVVGKHVV"
     CDS_motif       complement(3515..3577)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS36475_0001"
                     /evalue="1.80E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="IE289_RS36475"
                     /protein_end="169"
                     /protein_start="148"
                     /score="26.7"
                     /tool="antismash"
                     /translation="GEKVLVRGAAGGVGTAAVQLA"
     gene            4169..5062
                     /locus_tag="IE289_RS36480"
                     /old_locus_tag="GCM10010317_075210"
     CDS             4169..5062
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377124.1"
                     /locus_tag="IE289_RS36480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075210"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_217567791.1"
                     /transl_table=11
                     /translation="MTDEPVAVSDDPRHELGEFLRTRRTRLRPQDVGLEPGPRRRVAGL
                     RREELALLAGVSSDYYQRMEQGRDVRPSEQVLDALARALNFTAEETRHLHSLAAAARTP
                     ARRPRHHAPEEVPPTTLRLLRTMTSPSVVVGRFLDVLAWNPLAGALLGEFTQRPRSERN
                     LLSLLLHPEADRTCPERAATVAELVAMLRTQVAAEPGHPRAVELVGELAVRSDEFAGLW
                     ARHDVAETTRGRMRVRHPLVGELNLDWDAYPMPDATGPVLIAFTAEEGGPDAERLQLLA
                     GLLVAPGPAAASRPRP"
     gene            5103..5528
                     /locus_tag="IE289_RS36485"
                     /old_locus_tag="GCM10010317_075220"
     CDS             5103..5528
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559754.1"
                     /locus_tag="IE289_RS36485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075220"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_054228117.1"
                     /transl_table=11
                     /translation="MTLEDLVRLRRARDRMDREYAEPLDVAALARTALMSPGHFQRSFR
                     AAYGETPYSYLMTRRIERAKALLRRGDLTVTEVCLAVGCTSLGSFSSRFTELVGETPSA
                     YRARPHDHGAPIPPCVAQRLTRPTRHRNPEAEPGTRL"
     misc_feature    5111..5125
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.44"
                     /tool="antismash"
     gene            5725..6141
                     /locus_tag="IE289_RS36490"
                     /old_locus_tag="GCM10010317_075230"
     CDS             5725..6141
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674926.1"
                     /locus_tag="IE289_RS36490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075230"
                     /product="VOC family protein"
                     /protein_id="WP_054228118.1"
                     /transl_table=11
                     /translation="MDLKLSQCFIAVDDHDKALAFYRDVLGLEVRGDVAFEGMRWVTVG
                     SPLQPDVQIVLEPPAASPDISPADKQAMAELLAKGILRGVIFSTADCDALYERVRASGA
                     DVLQEPMDQPYGVRDCAFRDPAGNLLRFTERPDA"
     misc_feature    complement(6213..6227)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.99"
                     /tool="antismash"
     gene            6255..7109
                     /locus_tag="IE289_RS36495"
                     /old_locus_tag="GCM10010317_075240"
     CDS             6255..7109
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655739.1"
                     /locus_tag="IE289_RS36495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075240"
                     /product="hypothetical protein"
                     /protein_id="WP_190172793.1"
                     /transl_table=11
                     /translation="MPSARPRVLYVSDLAYPAKGRRYCDEDIFLTSRLREEFDLAVCHP
                     LDAAALMTGFDAVVVRNSGPVLHYQAQYDAFRKQAVTEGVRMYNQLSGKGDMAGKGYLL
                     DLTAAGFPVIPTIDRADDLDRLPDVDTYVVKPKLGADSIGLEFVPRDRLPELSYGNILV
                     QPRIDFRYEVSFYFVDHTFQYALYAPRPDERWALEPYEPTERDREFAQRFVDWNDIAYG
                     IQRVDACRAPDGELLLVELEDLNPYLSLDVLSPDTRDAFVSRVKTSLRGLIGQETVRAA
                     HGV"
     gene            7130..7888
                     /locus_tag="IE289_RS36500"
                     /old_locus_tag="GCM10010317_075250"
     CDS             7130..7888
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984433.1"
                     /locus_tag="IE289_RS36500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075250"
                     /product="VOC family protein"
                     /protein_id="WP_190172794.1"
                     /transl_table=11
                     /translation="MADPIRWTYAFVDRPMKDFDRACGFWTAVTATKLSEPRGDQGEFV
                     TLLPDGTDACVKAQGVDAGEGGAHLDLAVEDVPALAESARRLGAEIVTTEEDLVVLRSP
                     GGQPFCAVRWHGESARPPVVPGPTGATSRLDQVCLDVAPSRFEAEVAFWSALTGWESHP
                     GALPEFHLLRPPAGLPFRILLQRLDTARPAAAHLDIACSDIEAVRAHHERLGAVLVGHG
                     ARWAVMRDPVGGTYCLTGRDPATGSLPAPA"
     gene            complement(7931..8263)
                     /locus_tag="IE289_RS36505"
                     /old_locus_tag="GCM10010317_075260"
     CDS             complement(7931..8263)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959102.1"
                     /locus_tag="IE289_RS36505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075260"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_060898647.1"
                     /transl_table=11
                     /translation="MSEPLLHLTERSLWDAARASGAYEMSTRGRTLQEEGFIHCSLRHQ
                     VPGVASFLYGGYDGPDELVLLVIDPERLDVPVRYEAVKPGGEEFPHIYGPIPVAAVVDV
                     EVWESA"
     gene            complement(8351..8764)
                     /locus_tag="IE289_RS36510"
                     /old_locus_tag="GCM10010317_075270"
     CDS             complement(8351..8764)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384635.1"
                     /locus_tag="IE289_RS36510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075270"
                     /product="YciI family protein"
                     /protein_id="WP_190172795.1"
                     /transl_table=11
                     /translation="MKYLVMVQGTQADYEGMRGKGSAHAPAWSEQELQAMYAYMGAISD
                     DLAKSGELVEGQELAEPAQTRLVTSGQDGKAVISDGPYSETKELIAGYWVLECESLERV
                     TEIAERVTRCPGPEGATNYPVVIRPILDGAGDI"
     gene            complement(8761..9060)
                     /locus_tag="IE289_RS36515"
                     /old_locus_tag="GCM10010317_075280"
     CDS             complement(8761..9060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480393.1"
                     /locus_tag="IE289_RS36515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075280"
                     /product="hypothetical protein"
                     /protein_id="WP_190172849.1"
                     /transl_table=11
                     /translation="MGTDEHVCPACRQPVATVVRRHKTLGAFVPVWGPGPCHNPECETY
                     VGEPGAGVGARSGGGAEARSVPGTGFQPGRDTGEPREHPGESVAENEEAEGADS"
     misc_feature    9127..9140
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            complement(9137..9748)
                     /locus_tag="IE289_RS36520"
                     /old_locus_tag="GCM10010317_075290"
     CDS             complement(9137..9748)
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384633.1"
                     /locus_tag="IE289_RS36520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075290"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_190172796.1"
                     /transl_table=11
                     /translation="MGVVIRTADEGDRELVTRLLDEAFQDDPVSVWVFPDAAHRRAKHP
                     GLMGMFAEVVLAEGRVDVTEDGTACALWLSVPADAGHADEEDDGPVRLREAVDPDNERV
                     ELIGRLTAGIHPAGRAHEYLWMIGVAPERQGEGLGTALVRSVLDRCDREGLPAYLEASN
                     AGSRRLYERLGFALTGSPLDLPDGPRMWPMWREPQPGRGA"
     gene            complement(10001..11047)
                     /locus_tag="IE289_RS36525"
                     /old_locus_tag="GCM10010317_075300"
     CDS             complement(10001..11047)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136650.1"
                     /locus_tag="IE289_RS36525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075300"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_190172797.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.3e-60, bitscore:
                     197.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRQVAPGPVGGQEAAGILEYARASVDPELRRAVDSLPGSMRRIA
                     LYHFGWEHADGTPAAGNAGKAIRPALVLTATGALGGRHAAAVQAAAAVELIHNFTLLHD
                     DVMDRDTTRRHRPTAWTVFGDADAILAGDAMQALAQRLLAEDSHPASQAAAARLASCVV
                     ELCEGQHADTAMEKRGPAEVTLDEVLAMAEAKTGALLGCACALGGLYAGADEEDVDALD
                     AFGREAGLAFQLIDDVIGIWGDPSRTGKPAGADLIARKKSLPVVAALASGTPAATELAE
                     LYGVPYEEGELERTVLAVERAGGRDWAQFQAADRMSRAMHELSRAIPDPEAAGGLLALA
                     EFVTRRSN"
     gene            complement(11224..12630)
                     /locus_tag="IE289_RS36530"
                     /old_locus_tag="GCM10010317_075310"
     CDS             complement(11224..12630)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="IE289_RS36530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075310"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_190172798.1"
                     /transl_table=11
                     /translation="MSVGEEVRAGQGKPQQSLGTSAARNLATTTKSAPQMQEISSRWLL
                     RMLPWVNVQGGTYRVNRRLSYSVGDGRVTFVKTGDRVQVIPAELGELSVLRSFEDQEVL
                     GELAQRCQQREFAPGEVLASFGSPSDEVFLLAHGKVQKIGTGPYGGDAVLGVLADGAYF
                     GEQALIDPDAIWEYTARAVTAVTVLALARQDLEQVAERSDFLREHLTSLRAIPEQRTNK
                     YGEKEIDLAAGHTGEEDIPGTFVDYEAAPREYELSIAQTVLRLHTRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELINNREFGLLNNCEYDQRLQPHDGVPSPDDLDELLSRRRGTK
                     LFLAHPRAISAFGRECNKRGLVPESVEIAGNRIPTWRGVPLFPCNKIPVSDARTTSIIA
                     MRTGEAEQGVIGLQQAGIPDEIEPSLSVRFMGINEQAIISYLVTAYYSAAVLVPDALGI
                     LENVEIGRWR"
     misc_feature    complement(12680..12693)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.09"
                     /tool="antismash"
     gene            12896..13129
                     /locus_tag="IE289_RS36535"
                     /old_locus_tag="GCM10010317_075320"
     CDS             12896..13129
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535203.1"
                     /locus_tag="IE289_RS36535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075320"
                     /product="hypothetical protein"
                     /protein_id="WP_099920715.1"
                     /transl_table=11
                     /translation="MAGFLDRAKEQAQRGLTQGKQKLDEVQAQRAGGDLLKKLGAAYYA
                     ERRGSGSPEATQQALQALESHISVNGDAFLRS"
     gene            13311..13901
                     /locus_tag="IE289_RS36540"
                     /old_locus_tag="GCM10010317_075330"
     CDS             13311..13901
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142330.1"
                     /locus_tag="IE289_RS36540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075330"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_190172799.1"
                     /transl_table=11
                     /translation="MAPPMSAGGFLNQLREEGVTVVEVGDWEHHNRNHKGPWGPVYGVM
                     IHHSVTSGSEHTVGICRAGRPDLPGPLCHGVITKDGVLHLVGYGRANHAGLGDDDVLRA
                     VIAEKALPPDNEANADGNRHFYGFECENLGDGNDPWPEVQLEAIEKVAAAICRHHGWTE
                     RSVIGHLEWQPGKVDPRGFTMASMRERVRDRLK"
     gene            13957..14913
                     /locus_tag="IE289_RS36545"
                     /old_locus_tag="GCM10010317_075340"
     CDS             13957..14913
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571359.1"
                     /locus_tag="IE289_RS36545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075340"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_190172800.1"
                     /sec_met_domain="PALP (E-value: 2.1e-19, bitscore: 63.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSPTTPDGPTTPATPDVPEALDPTALRPRLPSPLCQVEDERFTR
                     RGVRLLLKRDDLIHPELIGNKWRKLAPNLRAAAGRTVVTFGGAYSNHLRATAAAGRLLG
                     LTTVGVVRGQELADRPLNPSLTRCAADGMRLHFVDRSTYRRKSEPETLAALLRSVDAED
                     AYVVPEGGSNSLAVRGCRELGAELRGHGGVDVAALACGTGGTLAGLAAGLAPDQRALGI
                     PVLKGGFLGSDISALQEAAFGGRRGTWSLDDRFHFGGYARTTPELDTFAADFEQRHDLP
                     VERLYVAKMLYGLVTLVEERAFTRGTTVAAVITGAPF"
     gene            complement(14930..16525)
                     /locus_tag="IE289_RS36550"
                     /old_locus_tag="GCM10010317_075350"
     CDS             complement(14930..16525)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="IE289_RS36550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075350"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_190172801.1"
                     /transl_table=11
                     /translation="MDVLPLLLLVAGSAAVAGLARRTPVPAPLLLVAAGLAVSYVPGVP
                     GYELDPEIVLPLVLPPLLYTAATDSSYLDLRAHMRPIALLSVGYVLFATLAVGWAAYLL
                     VPSLPLPAALVFGAVVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAYKVA
                     LAAAVGEGATWAGGVREFLLAAVGGVVVGLVLMVPIHWLRTHLNEALLQNTLSLLIPFA
                     AYGIAEQVHASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLKGLGQYQGAQAAWYAVAVFLVVVAARFVWVYPATFLPRILSARVREREGSPTW
                     KGPFIIGWAGMRGVVSLAIAFSIPLTVNGGASFPDRNLLLFLTFTTVIGTLVVQGLTLP
                     PLIRLLKLPGRDVQAETLAEANAQAQASRVAEERLDALLTDERNALPPPLADRLRSVLE
                     RRRNAVWERLGAVNPVTGETADDTYRRLSREMISAEREMFVKLRDHRYIDDEMLRTLLR
                     RLDLEEAAAYREAA"
     gene            16587..16847
                     /locus_tag="IE289_RS36555"
                     /old_locus_tag="GCM10010317_075360"
     CDS             16587..16847
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639609.1"
                     /locus_tag="IE289_RS36555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075360"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_054228128.1"
                     /transl_table=11
                     /translation="MKQCTHADELPHPEPGPLSETCLECQAAGTHPVQLRLCLSCGHLG
                     CCDSSPLRHATEHFKETGHPVMRTFEPGESWRWCFVDHVLA"
     misc_feature    complement(16955..16968)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            17109..17522
                     /locus_tag="IE289_RS36560"
                     /old_locus_tag="GCM10010317_075370"
     CDS             17109..17522
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="IE289_RS36560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075370"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_054228129.1"
                     /transl_table=11
                     /translation="MSQIAGEPATKDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLIDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVDSTVAEDKTVSISLYKQRGAGPGPA"
     gene            17519..18613
                     /locus_tag="IE289_RS36565"
                     /old_locus_tag="GCM10010317_075380"
     CDS             17519..18613
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984444.1"
                     /locus_tag="IE289_RS36565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075380"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_075028856.1"
                     /transl_table=11
                     /translation="MRNGDGPVRDEERGTRELPAGRVDGLDGPRRAVEGVDGIPEQARP
                     HPEDAQESLSGQDDGQRDPEGAAPSTSSEGRRLVTGGTMSEHERHDKPGVQSVQGTQHG
                     PSAQHIQHDPQDRSGARAMFIELRKLQDGSAEYAELRNQLVRMHLPLVEHLARRFRNRG
                     EPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQ
                     ELRLALTTATAELSQQHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLDVPDTDD
                     ESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGI
                     SQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(18742..19191)
                     /locus_tag="IE289_RS36570"
                     /old_locus_tag="GCM10010317_075390"
     CDS             complement(18742..19191)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000792.1"
                     /locus_tag="IE289_RS36570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075390"
                     /product="hypothetical protein"
                     /protein_id="WP_190172802.1"
                     /transl_table=11
                     /translation="MSAEQIPTPDAPSAEPRPGRLTAAAALAALEGLVLAVGGVWMLVL
                     GATGDSGDRQQGVTLGVTLIVLALLPLLAARGLLLRRSWSRGPAVITQIMALPVAYSLL
                     QADSVAIPAGIALAAVAITALVLLVNSETTRALGIRGPGAAEETK"
     misc_feature    complement(19189..19204)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 24.53"
                     /tool="antismash"
     misc_feature    19312..19331
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.07"
                     /tool="antismash"
     gene            19350..20318
                     /locus_tag="IE289_RS36575"
                     /old_locus_tag="GCM10010317_075400"
     CDS             19350..20318
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="IE289_RS36575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075400"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_190172803.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEVVTTEYRGHARD
                     LGRQAAESDDIELVVALGGDGTVNEVVNGLLHNGPDLDRLPRLAVVPGGSTNVFARALG
                     LPNDAVEATGALLDALREDRERAIGLGLAAGTPGTEDESVPSRWFTFCAGLGFDAGVIG
                     RVEQQRERGKRSTHALYLRQVARQFLDEPHRRHGTITLDQPGQDPVTDLVMSIICNTSP
                     WTFLGNRPVYASPKASFDTGLDVLALNRMSTGAVARYATQLLTSSPERGPHGKHALSLH
                     DLTDFTLHSKAPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(20408..20417)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20579..20594)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20582..20593
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20638..20895
                     /locus_tag="IE289_RS36580"
                     /old_locus_tag="GCM10010317_075410"
     CDS             20638..20895
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="IE289_RS36580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_075410"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_006380970.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQATA"
     misc_feature    21013..21027
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.7"
                     /tool="antismash"
ORIGIN
        1 gtcggcctgg ccgacaaggc ggccaactac ccctcgcagc tctccggcgg tcagcagcag
       61 cgtgtcgcca tcgcccgagc gctggcgatg gacccgaagc tgatgctctt cgacgagccg
      121 acctcggcgc tcgacccgga gctggtcggt gacgtcctcg acgtcatgcg cgacctcgcc
      181 gagtccggca tgacgatgat cgtcgtcacc cacgagatgg gcttcgcccg cgaggtgggc
      241 gactcgctgg tcttcatgga cggcggtgtg gtggtcgagt ccggccaccc gcgtgacgta
      301 ctgacgaacc cgcagcacga gcggacgcag tcgttcctgt ccaaggtgct ctgagccacg
      361 gacaagagtg aaggggcggt acgggattcc cgtaccgccc cttcttcgtc cggtccgcgc
      421 ccggattcct cgtccggacc cccgcggcct gcttacttca ctgccagcac cagcgcgtcg
      481 gacggcgacc gccacaccgc ccgcgcctcc ccgaagccct tttcgcgcag cacgcgcgtg
      541 tgccagtcga cggacggcat gtcgccgtcg gcgtgctccc cgtagatctc gaagcggcgg
      601 gcggtcggcg cggcgagggc ggggtcctgg gccgccagct cccaccaggc ggcccagtcg
      661 agcaccccgc gcgccctggc ctggtccatc cgggcgtgcc gctgggcgcg ctcggcctcg
      721 ttgatccggg gcgtggactc gtcgatcatg tggtcggcgt tcatgaagac gccgccgtcg
      781 cggacgagct ccgcgacctg gccgtagagg accgcgaggg gctcgctgtg cagccagtgg
      841 agggccgtgg cggtcaggac ggcgtcgtac gagtcgtacg gcagccgggt cgcccagtgc
      901 gggtccttga ggtcggccgt gacgagggag accctgtcgt cgcccgcgaa ggtgccctcg
      961 gcgatggtga gcagcgccgg gtcgaggtcg acgccggtgc tggtggcctt cgggaagcgg
     1021 tcgaggagcc gggccgtgat ggtgccggtg ccgcaggcca ggtcgaggac gcgcggctcc
     1081 gggccgcaca gggcctcgac catgtcgagc atcacccgga agcgctcctc gcggtccggc
     1141 atgtaccact cctgttgccg gtcccagctc ttctgccagg cgtgccagtc ggtgccgttg
     1201 ccatggatct cgtcgctgtc gattccggtg ccgacggtca tggaagcctc ttctccgttc
     1261 gtcttcactc gcccgcgtaa taccctggaa gcgcaatcag ccgttacccc tgaccgcacg
     1321 catgacgata gagcgcctcc gtaaggacta caagtggaac tggcctatta ctcggattac
     1381 gcggtacgcc tcgtcaacac cgaggagccg acccggggca aggactcgct cacctcggtc
     1441 gaggcggtcc gggacctctt cggagggaac tcctccgcgg cccgccgcgc cacggacgcg
     1501 gacgtcaccc gcttccggtc ggtccgcgcc cggctgcgcg ccgtcttcga ggcggccgac
     1561 ggcggcgacg agaccctctc cgtggacctg ctgaactcac tcctcctgga gttccccgtc
     1621 agcccgcaga tctccggcca cgaccaccgg gacgacgacg ggcgcccgct gtggcacatg
     1681 cacctggcgg accacccgtc gaacgcgacc gcgggctacg cggcgatcgc cgccatggga
     1741 ctcgccttcc acctcaccga gtacggcgtg gaccgcctcg gcctctgcga ggcggccccc
     1801 tgccgcaacg cgtacctgga cacgtcgacg aaccgctccc ggcgctactg ctcggaccgc
     1861 tgcgcgacgc gcgccaacgt ggccgcctac cgggctcgca aacgcctgga ggccgaccgg
     1921 tcggagagca ccggcctggc ggcgccgagc gcccagcgga cgaccgcgag cggcgagcgc
     1981 tgacccggca ggtggggccg gtagcggaaa cgcacctttc cgaggacgag gtcctcgggc
     2041 acggtcccgt agtcggtgct gtccccaccc gcgtaggcgt tgtccccgag cacccaccaa
     2101 cccccctcgc gccgctccgc gatccgcttc acgaccagca ggtcctgctg gaacggatgg
     2161 cgcagaacga ccacgtcacc gggcctgacc cgggccccgt actgcacgac gagccgatct
     2221 ccgtgctgga gcgtgggcac catggagggc cccgtcacct cggccgcccc gaacggcagc
     2281 acggccctcc cacgctcggt ctcctgcgac agctccggca tcaccggcac ctccccggtc
     2341 catcctccac cagtcccagt ctcaccctgg acttttgtcc taagcccatg ggggcactcg
     2401 agaaaagacg tctcccacgg agtaatgtcc cacctgagaa gacgatcacg aggaaggaca
     2461 gctcaatgct ctcccgcctg tttgccccca aggtcaaggt cagcgcgcac tgcgacctgc
     2521 cctgcggcgt gtacgacccg gcccaggccc gcatcgaggc ggagtcggtg aaggccgtcc
     2581 aggaaaagat ggccggcaac gacgacccgc acttccaggc tcgcgccacc gtcatcaagg
     2641 agcagcgcgc cgagctcgcc aagcaccacg tgtcggtgct ctggagcgac tacttcaagc
     2701 ccccgcactt cgagaagtac ccggagctgc accagctggt caacgacacc ctgaaggccc
     2761 tctcggccgc caaggcgtcc acggacccgg ccacgggcca gaaggcgctg gactacatcg
     2821 cccagatcga caagatcttc tgggagacca agaaggcctg acctttggtc atacggctcg
     2881 acccgcgacc tgttcggttt ctccggtcac gcggtcccgc tgcccgcacc cggcccgcgg
     2941 gacgccgaac acggcgtccc tgacggtccg ggtgcggtct tctttcgccg ggcttcttcc
     3001 gccggcgttt cgttcgtcct tcgtccgggc ttcgttcggg cttcgttcgg gcttcgttcg
     3061 tccgacgtca ttcggatacg gcgaccacgt gcttgccgac gacgccgccg cgttcgaagg
     3121 cctggtgcgc cgcggcgatg tccgcgagtg ggtacacgcc gttcaccacc gggcgcagcg
     3181 ctcccgaggt gacgtggtcg gccagggcgc gcagcacggt ggcgtcgggg ttggcgctga
     3241 aggtgcggac gcgacgggcg ccgtacacgc tggatgccgc gatcgcggcc agggcggggg
     3301 ccgacagtcc gacggtgacc atccggccgc ccttggccaa ccggctccgg tagcagttca
     3361 gttccgtgcc gaccgtgtcg acgatgacgt cgaaggggcc gatccggtcc gaggtggtgg
     3421 agccgtggtc gaggacctcg tcggcgccga ggtcggtgag ggcgggggcg tgacgggcgc
     3481 gggccagtgc ggtcacgtgg cagcccaggg cgtgggcgag ttggacggcg gccgtgccga
     3541 cgccgcccgc cgcgccgcgg accaggacct tctctccggg cgcgaggcgt acggtgtccc
     3601 gcaccgcgat cagcgccgtc gcaccggcga cgaccaggga ggccgcgtcg gccgcggaga
     3661 gtgccgccgg ggcgggcgcg agccggtccg cggggacgac gacgtactcg gccgccccgc
     3721 cgatggtgtg ccgctgccgg gggtgaaccg tgccccacac ccggtccccg acccgcaggc
     3781 cctcgacgcc ggtgccggat ccggtgacga cgccggcgaa gtccagccct gtgccgagcg
     3841 ggaaccggcg ccccgagacg atcttcatct ccccggaacg gacgatcacg tcgtggccgt
     3901 tcacgctgga cgcctcgacg cggaccagta cttcacccgc gccgggggcg ggccggtcga
     3961 cgtcgttgat ccgcagcacg tccgccgcgt cgccgtaact cgtgatctga gcggccttca
     4021 tggcgctgtt cccttccgcg gtcggctgtt gcggttcaga tcctggtacc gggccgcggc
     4081 atcacggtcg ttcgtctttt ccccggttcg gctttcctgg gtccggcaga cccaccctcg
     4141 cgggccgcgc cgcgggcata ctgaagccgt gaccgacgag cccgtcgcgg tgagcgacga
     4201 tccccgacac gaactcgggg agttcctccg gactcgccgc acccgactgc ggccgcagga
     4261 cgtcggtctg gaacccggtc cgcggcggcg cgtcgccggg ctgcggcgcg aggaactggc
     4321 cctgctggcc ggggtcagtt cggactacta ccagcgcatg gagcagggcc gcgacgtacg
     4381 cccctccgag caggtcctgg acgccctcgc gcgcgccctc aacttcaccg ccgaggagac
     4441 ccggcatctg cacagcctcg ccgccgccgc gcgcacgccc gcgaggcgcc cgcgccacca
     4501 cgcgcccgag gaggtgccgc ccaccaccct gcggctgctg cgcacgatga cctccccctc
     4561 cgtggtcgtc ggccgcttcc tggacgtact ggcgtggaac ccgctcgccg gtgccctgct
     4621 cggcgagttc acccagcgcc cgcggagcga acgcaatctg ctgtcgctgc tgctgcatcc
     4681 ggaggccgac cggacgtgtc cggagcgggc cgccaccgtc gccgagctgg tcgcgatgct
     4741 gcgcacgcaa gtcgcggccg agccgggaca tccgcgcgcc gtcgagctgg tcggtgaact
     4801 cgccgtccgc agtgacgagt tcgcgggcct gtgggcacgt catgacgtgg cggagaccac
     4861 gcgcggccgg atgcgcgtcc gtcacccgct ggtcggggag ctgaacctgg actgggacgc
     4921 gtacccgatg ccggacgcca ccggccccgt actcatcgcc ttcaccgccg aggagggcgg
     4981 gcccgacgcc gagcgtctcc agttgctcgc cggcctgctc gtcgcccccg gcccggcggc
     5041 tgcgtcccgt ccgcggcctt gacccaccgg cctctgtcag tggcgcgtgc catcctgaag
     5101 aaatgactct ggaggatctg gtccggctgc gccgggcacg cgaccggatg gaccgcgagt
     5161 acgcggagcc gctggacgtc gccgcgctcg cgcgcaccgc gctgatgtca cccgggcact
     5221 tccagcggag cttccgggcg gcgtacgggg agacgccgta cagctatctc atgacccgcc
     5281 gaatagagcg ggccaaggcc ctgctgcggc ggggcgacct gacggtcacg gaggtctgcc
     5341 tcgccgtggg ctgtacgtcg ctcggttcgt tcagctcccg cttcacggag ctggtcggcg
     5401 agaccccgag cgcgtaccgg gcccggccgc acgaccacgg cgccccgatc ccgccgtgcg
     5461 tggcccagcg cctgacccgc ccgacccgcc accgcaaccc ggaagcggaa ccgggtacgc
     5521 ggctctagga cctgtccggc cgatcacggt ggaggaaagc tgcggcgcct cgtcgatacc
     5581 ggtgagcggg gtttggtgcg tgcagctgca aggcggagga gggagtcatg gcggagccat
     5641 ggcgaccgac gacaacgccg cagatgtgcg caccaaaccc cgcgtctccg ccgtgatcgg
     5701 ccggacaggt cctagcgtgg ggccatggat ctgaaactct cacagtgctt catcgccgtg
     5761 gacgaccatg acaaagcgct cgccttctac cgggacgtcc tcggcctgga ggtccggggt
     5821 gacgtcgcct tcgaggggat gcgctgggtg acggtcggct ccccgctcca gccggacgtc
     5881 cagatcgtcc tggagccccc cgccgcgagc ccggacatct cccccgccga caagcaggcc
     5941 atggccgagc tcctcgccaa gggcatcctg cgcggtgtca tcttctccac cgccgactgc
     6001 gacgccctct acgaacgcgt ccgcgcctcc ggcgccgatg tcctccagga gccgatggac
     6061 cagccgtacg gcgtccgcga ctgcgccttc cgcgacccgg cgggcaacct cctgcgcttc
     6121 accgaacgcc ccgatgcctg accccggcca cccccgcctc ggtcggcggg aggcagacta
     6181 cgtccgtgtg ttccgtggga gcgggtcgcc catggaacgg aacgtctgaa gtcccgtagt
     6241 ccgaggagtc atcgatgccg tccgcgcgcc cccgcgtcct ctacgtcagt gacctggcct
     6301 acccggccaa ggggcggcgg tactgcgacg aggacatctt cctcacctcc cggctgcgtg
     6361 aggagttcga cctcgccgtg tgccaccccc tggacgcggc cgcgctgatg accggcttcg
     6421 acgccgtggt cgtgcggaac agcgggcccg tgctgcacta ccaggcgcag tacgacgcgt
     6481 tccggaagca ggcggtcacg gaaggtgtcc gcatgtacaa ccagctgtcc ggcaaggggg
     6541 acatggcggg gaaggggtac ctgctggacc tcaccgcggc ggggttcccg gtcatcccga
     6601 ccatcgaccg cgcggacgac ctcgaccggc ttccggacgt cgacacctac gtcgtgaagc
     6661 ccaagctggg agcggattcc atcggcctgg agttcgtacc gcgcgaccgg ttgcccgaac
     6721 tgtcgtacgg caacatcctc gtccagccac gcatcgactt ccgctacgag gtgtccttct
     6781 acttcgtcga ccacaccttc cagtacgccc tgtacgcccc ccgcccggac gagcgctggg
     6841 ccctggaacc gtacgagccg accgagcggg accgggagtt cgcgcagcgg ttcgtcgact
     6901 ggaacgacat cgcgtacggc atccagcgcg tcgacgcctg ccgggccccc gacggcgaac
     6961 tgctcctcgt ggagttggag gacctgaacc cctatctgtc cctggacgtc ctctcccccg
     7021 acacgcggga cgccttcgtc tcacgggtga aaacatcgtt gcgcgggctg atcggacagg
     7081 agacggtacg agccgcacac ggtgtctgag agggagcggg aaacgaccca tggctgaccc
     7141 cattcgatgg acctacgcct tcgtcgaccg gcccatgaag gacttcgatc gcgcctgcgg
     7201 cttctggacc gcggtcacgg cgacgaagct gtccgaacca cgcggtgacc agggcgagtt
     7261 cgtgaccctg ctgcccgacg gcaccgacgc ctgcgtcaag gcgcagggcg tcgacgcggg
     7321 cgagggcggc gcccatctgg acctcgccgt cgaggacgta ccggcgctgg cggagtcggc
     7381 ccggcggctc ggtgccgaga tcgtcaccac cgaagaggac ctggtcgtcc tgcgctcccc
     7441 cggcggccag ccgttctgcg cggtccgttg gcacggcgag tcggcgcggc ctccggtcgt
     7501 cccgggcccc accggcgcca ccagccgcct cgaccaggtg tgcctggacg tggcgccctc
     7561 ccgcttcgag gccgaagtcg ccttctggag cgccctgacc ggatgggagt cgcaccccgg
     7621 cgcgctcccg gagttccacc tgctcaggcc gcccgccggg ctccccttcc gcatcctcct
     7681 gcaacgcctc gacaccgccc gccccgccgc cgcccacctc gacatcgcct gctcggacat
     7741 cgaggcggta cgcgcccacc acgagcggct cggtgccgtg ctcgtcggcc acggcgcccg
     7801 ctgggccgtc atgcgggacc cggtcggcgg cacgtactgc ctgaccggcc gggacccggc
     7861 gacgggcagc ctcccggccc cggcctgatc cgaagaacga cccgaagcga acgacccgag
     7921 gcggacagcc ctaggcggac tcccacacct ccacgtccac cacggccgcc accggaatcg
     7981 gcccgtagat gtgcgggaac tcctcgcccc cgggcttgac cgcctcgtag cgcaccggca
     8041 cgtccagccg ttcgggatcg atgaccagga gcaccagctc gtcggggccg tcatacccgc
     8101 cgtacaggaa ggaggcgacc ccggggacct ggtgccgcag cgagcagtgg atgaagccct
     8161 cctcctggag ggtgcggcca cgggtggaca tctcgtacgc gccggacgcg cgcgccgcgt
     8221 cccacaggga gcgctcggtg aggtgcaaca agggttcgga catgccgaca cgctacggcc
     8281 tcagccgggc cgcccgcgtc tccaagtagc gccgctcggg gagaccgagg gtcccgcggg
     8341 cgcatcccgc tcagatgtct ccggcgccgt ccaggatggg gcggatgacc accggatagt
     8401 tcgtggcgcc ctcgggacct gggcagcggg taacgcgctc ggcgatctcg gtgacccgct
     8461 ccaggctctc gcactccagt acccagtagc cggcgatcag ctccttggtc tcgctgtacg
     8521 gcccgtcgga gatgacggcc ttcccgtcct gcccggacgt gaccaggcgg gtctgtgccg
     8581 gttcggccag ctcctgtccc tcgacgagct caccggactt cgcgaggtcg tcgctgatcg
     8641 cgcccatgta cgcgtacatc gcctgcagct cctgctcgct ccaggccggg gcgtgcgcgg
     8701 agcccttgcc ccgcatgccc tcatagtccg cctgcgtacc ctgcaccatc accaggtact
     8761 tcatgagtcg gctccctcgg cttcctcatt ttccgcgacg gactccccgg gatgctcccg
     8821 gggctccccg gtgtccctgc cgggttggaa tccggtcccg ggtacggacc gggcctccgc
     8881 gccgcctccg gacctggccc cgactccggc gccgggctcg ccgacatacg tctcgcactc
     8941 cgggttgtgg caggggccgg gaccccatac gggaacgaac gcgcccagcg tcttgtggcg
     9001 ccgcacgacg gtggcgaccg gctgccggca ggcggggcag acatgctcat cggtgcccat
     9061 gcattcaggg taggtcggga gacgcttcag cgcttcctgc tgtacgtccg cacgaagacg
     9121 ccgctcttga acccgatcag gccccccgcc cgggctgcgg ctcgcgccac atcggccaca
     9181 tccgcggacc gtccggcagg tcgagagggc tccccgtgag ggcgaagccg agacgctcgt
     9241 agagtcggcg gctgccggcg ttgctcgcct ccagataggc gggcagaccc tcgcggtcgc
     9301 agcggtcgag gaccgaccgg acgagcgcgg tgccgaggcc ctcgccctgg cgctccggcg
     9361 ccacgccgat catccacagg tactcgtggg cgcggcccgc gggatggatc ccggccgtca
     9421 ggcggcctat cagctcgacc cgctcgttgt ccgggtcgac ggcctcacgc agccgtacgg
     9481 gaccgtcgtc ctcctcgtcg gcgtggccgg cgtcggcggg cacggacagc cacagcgcgc
     9541 acgccgtgcc gtcctccgtg acgtccacgc gcccctcggc gagcacgacc tcggcgaaca
     9601 tccccatcag cccggggtgc ttggcgcggc ggtgcgcagc gtccggaaag acccagacac
     9661 tcaccgggtc gtcctggaac gcctcgtcga gcagccgggt gaccagctcc cgatcgccct
     9721 cgtccgccgt acggatcacc acacccatgt cccaccctct cgcctcaacc gccgctgatc
     9781 gtacggctgt tgcagcctag ggcctgccgg gcctgccggg gctgtcgggc ctgtccgggc
     9841 ctgagtgggg cgggccccgc gcaccgtggg gatgtgcggg acccgctccg gccggagccc
     9901 ggtgccgtac ggaggtcagg tgccgtacgg tcccggaggc cccggggtct tcaaccgccc
     9961 ttctgaagga tcgagcgggt catccgaagg ttcgaacggg tcagttgctg cgccgcgtca
    10021 cgaactccgc gagcgcgagg aggccgcccg ccgcctccgg gtcggggatc gcccgggaca
    10081 gctcgtgcat cgcccgggac atccggtcgg ccgcctggaa ctgcgcccag tcacggccgc
    10141 ccgcccgctc gacggccagt accgtgcgct ccaactcccc ttcctcgtag ggaactccgt
    10201 acagctcggc gagttccgtc gccgccgggg tgccggaggc gagcgcggcg accacgggca
    10261 gggacttctt acgggcgatg aggtccgccc cggccggctt gccggtgcgg ctcgggtccc
    10321 cccagatccc gatcacgtcg tcgatcagct ggaaggcgag gccggcctcc cggccgaacg
    10381 cgtccagcgc gtcgacgtcc tcctcgtccg cccccgcgta cagcccgccg agcgcacacg
    10441 cgcagccgag cagcgcgccg gtcttggcct cggccatggc gagcacttcg tcgagggtga
    10501 cctcggcggg tccgcgcttc tccatggccg tgtccgcgtg ctgcccctcg cacagctcga
    10561 cgacgcagga cgcgagccgg gcggcggcgg cctgggacgc cgggtgcgag tcctcggcga
    10621 gcagccgctg ggcgagcgcc tgcatggcgt ccccggcgag gatcgcgtcg gcgtcgccga
    10681 acacggtcca cgcagtgggg cggtgtctgc gggtggtgtc ccggtccatg acgtcgtcgt
    10741 gcaacagcgt gaagttgtgg atcaactcca cggcggccgc cgcctgtacg gcggccgcgt
    10801 gccgaccgcc gagcgctccc gtggcggtga gcaccagggc cgggcggatc gccttgcccg
    10861 cgttgcccgc cgccggggtg ccgtccgcgt gctcccagcc aaagtggtag agcgcgatcc
    10921 ggcgcatgga tcccggcagc gagtcgacgg ccctgcgcag ctcggggtcg acggacgccc
    10981 gggcgtactc caggatgccc gccgcctcct gtccgcccac cgggccgggc gcgacctgcc
    11041 gatccatggg cctcccgtcc gcggaaccgc cgtccggccc gtccgcggga ccgccgtccg
    11101 agggcctgcc ctctatgggc ttgccgatgc gaccccgccc gtccagggtc tcggccggac
    11161 tccgcctcgc cctcggtgtt cccgcctgat cgggcgggaa cacggcggcc ggcgtcggga
    11221 aggtcaccgc cagcggccga tctcgacgtt ctccaggatg ccgagggcgt ccggcacgag
    11281 aaccgccgcc gagtagtacg ccgtcaccag gtaggagatg atcgcctgtt cgttgatgcc
    11341 catgaagcgc accgacaggc tcggctcgat ctcgtccggg atgcccgcct gctggaggcc
    11401 gatgacaccc tgctcggcct cgccggtacg catggcgatg atcgaggtcg tacgggcgtc
    11461 gctgacgggg atcttgttgc acgggaacag cggcacaccg cgccaggtcg ggatgcggtt
    11521 gcccgcgatc tcgacgctct cggggaccag tccgcgcttg ttgcactcgc ggccgaacgc
    11581 ggagatcgcg cgcgggtggg cgaggaacag cttggtgcca cgtcggcggc tgagcagctc
    11641 gtccaggtcg tcggggctgg gcacgccgtc gtgcggctgg agccgctggt cgtactcgca
    11701 gttgttgagc agtccgaact cccggttgtt gatgagctcg tgctcctggc gctccttcag
    11761 cgcctcgacg gtgaggcgga gctgctgctc cgtctggttc atcggctggt tgtagagatc
    11821 ggccacacgg gtgtgcaggc gcagcacggt ctgggcgatg ctcagttcgt actcgcgcgg
    11881 cgccgcctcg tagtccacga aggtgccggg gatgtcctcc tccccggtgt ggccggccgc
    11941 gaggtcgatc tccttctcgc cgtacttgtt ggtgcgctgc tccggaatcg cgcgcagcga
    12001 cgtgaggtgt tcgcgcagga agtcggagcg ctcggcgacc tgctcgaggt cctggcgggc
    12061 cagcgcgagc acggtgaccg cggtgacggc gcgggccgtg tactcccaga tggcgtccgg
    12121 gtcgatgagc gcctgctcgc cgaagtacgc gccgtcggcg aggacgccga ggaccgcgtc
    12181 gccgccgtac gggccggtgc cgatcttctg caccttgccg tgcgcgagca ggaacacctc
    12241 gtcggacggg ctgccgaacg aggcgagcac ttcgcccggt gcgaactccc gctgctggca
    12301 ccgttgggcg agctcgccga gcacctcctg atcctcgaac gagcggagca ctgacagctc
    12361 gccgagctcc gcggggatga cctgcacacg gtcaccggtc ttcacgaacg tcacgcggcc
    12421 gtcgcccacg gagtagctga gccgccggtt cacgcggtac gtgccaccct gcacgttcac
    12481 ccacggaagc atgcgcagca gccaccgtga gctgatctcc tgcatctggg gtgcggactt
    12541 ggtggtggtg gccaggttcc gcgcggccga tgtgccgaga ctctgctgcg gcttgccctg
    12601 ccccgcacgg acctcttcgc ctaccgacat gaaaattgcc ctcccggtcg tgcgctgatc
    12661 tgcgccgacc agccttccat cacggagcgt gccggtgcta ttacacgaat gagcgggaat
    12721 ggatcacggg ggattgggca gaggatccac ttttgtcgat cgatcgaaca gccggcgccg
    12781 tcgtcctcga acagccgcag ccctcgcctt cgaacagcgc ggagccgttg cgagcgggaa
    12841 ctccgagatc aggccaaccg tttgacgcgg tgacggacga cgacaggaga cggcaatggc
    12901 aggcttcctg gaccgcgcca aggaacaggc gcagcgaggg ctcacgcagg gcaagcagaa
    12961 gctcgacgag gtgcaggcgc agcgtgcggg cggcgacctc ctgaagaaac tgggcgcggc
    13021 gtactacgcg gagcggcgcg gcagcggctc ccccgaggcg acccagcagg ccctgcaggc
    13081 gctggagagc cacatctccg tgaacgggga cgcgttcctg cgctcctgac aggcctcgcg
    13141 gacacaccgc gaacgcgccg tgaacgcgct ggtcagacgc gcccgcgccc ctgaccggat
    13201 cgactcgcac gccgtacgaa cggctgggcc ggagccctgg gttccgggta caagctgcgg
    13261 tacgagacgg ccgcgaccgg tggccgccgc gcagtgcgaa ggaggcggcc atggccccac
    13321 ccatgtccgc gggcggtttc ctgaaccagc tcagggagga aggcgtcacc gtcgtcgagg
    13381 tcggcgactg ggagcatcac aaccgcaatc acaaggggcc ctggggtccg gtgtacggcg
    13441 tgatgatcca ccactcggtg acctcgggca gcgagcacac cgtcgggatc tgccgcgcgg
    13501 gccgcccgga cctgcccggt ccgctgtgcc acggcgtcat caccaaggac ggtgtcctgc
    13561 acctcgtggg ctacggccgg gccaaccacg cgggtctggg tgacgacgac gtgctgcgcg
    13621 ccgtgatcgc ggagaaggcg ctcccgccgg acaacgaggc gaacgccgac ggcaaccgcc
    13681 acttctacgg cttcgagtgc gagaacctcg gcgacggaaa tgatccgtgg cccgaggtac
    13741 agctagaggc catcgagaag gtcgcggccg cgatctgccg ccaccacggc tggacggagc
    13801 gttcggtcat cggccacctg gagtggcagc cgggcaaggt cgacccgcgc ggcttcacga
    13861 tggcctcgat gagagagcgc gtccgcgacc gcctcaagtg acggacgggc gcggggtggc
    13921 cgcccgcata ccggacaggt gtccgacaat ggtggggtgc ccagccccac aaccccggac
    13981 ggcccgacca ccccggccac tccggacgtc cccgaagcgc tcgacccgac cgctctgcgg
    14041 ccgaggctgc cctcgccgct gtgtcaggtc gaggacgagc gcttcacgcg ccgtggcgtg
    14101 cggctgctgc tcaagcggga cgatctgatc cacccggagc tgatcggcaa caagtggcgc
    14161 aagctcgccc cgaacctccg cgcggcggcg ggccgcacgg tggtcacgtt cggcggcgcg
    14221 tactccaacc atctgcgcgc caccgccgcc gcgggccgcc tcctcgggct gacgaccgtg
    14281 ggggtggtcc gcggccagga gctggccgac cgccccctca acccctcact gacccgctgc
    14341 gcggccgacg gcatgcgact gcacttcgtc gacagatcga cgtatcgccg caagagcgaa
    14401 ccggagacgc tggccgccct gctgcgctcg gtggacgccg aggacgcgta cgtcgtcccg
    14461 gagggcggca gcaactccct tgccgtacgc ggctgccggg aactcggcgc ggagctgcgg
    14521 ggccatggcg gtgtcgacgt ggccgccctg gcctgcggca ccggcggcac cctcgccggc
    14581 ctggccgccg gcctcgcccc cgaccagcgg gccctgggga tccccgtcct caagggcggc
    14641 ttcctgggga gtgacataag cgccctccag gaagccgcct tcggcggccg gcgcggcacc
    14701 tggtcactcg acgaccgctt ccacttcggc ggttacgccc gcaccacgcc cgaactcgac
    14761 accttcgccg cggacttcga acagcgccac gacctgcccg tggaacgtct ctatgtcgcc
    14821 aagatgctct acggacttgt caccctggtg gaagagaggg cgttcacacg ggggacgacg
    14881 gtggcggcgg tgatcacggg ggcaccgttc tgagccctcg tacggcgcct cacgccgctt
    14941 cccggtaggc cgccgcctcc tccaggtcga gtctgcgcag gagcgtgcgg agcatttcgt
    15001 cgtcgatgta gcggtggtcg cggagtttca cgaacatctc gcgttcggcg ctgatcatct
    15061 cgcgggacag gcggcggtag gtgtcgtcgg cggtctcccc ggtcaccggg ttgacggcgc
    15121 cgagccgttc ccagacggcg ttgcggcggc gttccaggac cgagcggagc cggtcggcga
    15181 gcggcggggg cagggcgttg cgctcgtcgg tgaggagtgc gtcgaggcgc tcctcggcga
    15241 cccgggacgc ctgcgcctgg gcgttcgcct cggcgagcgt ctcggcctgg acgtcgcgcc
    15301 ccggcagctt gagcaggcgg atgagagggg gcagggtcag cccctggacg accagggtcc
    15361 cgatcacggt ggtgaaggtg aggaagagga gcaggttgcg atcggggaag gaggcaccac
    15421 cgttcacggt gagcgggatg gagaaggcga tggcgagcga gaccaccccg cgcattccgg
    15481 cccagccgat gatgaacggg cccttccagg tgggggaccc ctcgcgctcc cggacgcgcg
    15541 ccgacaggat ccgcggcagg aaggtggcgg gatagaccca cacgaaccgg gcggcgacca
    15601 cgaccaggaa gacagccacc gcataccagg cggcctgggc tccctggtac tggccgaggc
    15661 ccttgaggac gaccggcagt tgcagtccga tcagggcgaa caccgccgac tccaggacga
    15721 acgcgaccat cttccacacc gcctcctcct ggagccgggt cgcgaagtcc acctcccagg
    15781 cacggtgccc gaggtagagc gcgacgacga ccaccgcgag cactccagag gcgtgcacct
    15841 gctcggcgat cccgtaggcg gcgaagggga tcaacaagga gagggtgttc tggagaagtg
    15901 cctcattcag gtgcgtgcgc aaccagtgga tcggaaccat caggacgaga ccgacgacca
    15961 cacccccgac tgccgcgagg aggaactcac ggacaccgcc cgcccaggtc gcgccctcgc
    16021 cgaccgcggc agcgagggcc accttgtagg cggtgatcgc ggtcgcgtcg ttcaccaggg
    16081 actcgccctg aaggatcgtg gtgatccgtg agggcagccc cacccggcgc gccaccgccg
    16141 tggccgccac cgcgtccggc ggcgccacca ccgctccgaa gaccagcgcc gcgggcagcg
    16201 gcaggctcgg cacgagcaga taggcggccc agccgacggc cagcgtcgcg aagagcacgt
    16261 accccaccga cagcagcgcg atgggccgca tatgcgcccg aagatcgagg tacgagctgt
    16321 cggtggccgc cgtgtacagc agcgggggca gcaccagcgg gagcacgatc tccgggtcga
    16381 gttcgtatcc gggcactcca gggacgtacg agacggccag gcccgccgcg acgagcaaca
    16441 gcggcgccgg caccggggta cgacgggcga gcccggcgac cgcggcgctc cccgcgacca
    16501 gcaacagcag tggcaatacg tccatcgtct tccgcccgcc ctcgttttcg cgcgacatcc
    16561 cgcacgcccg acgtaacctg gcaatcatga aacagtgcac gcacgccgac gagctgccgc
    16621 accccgaacc cggaccgctg agcgagacct gcctggagtg ccaggccgcc ggtacacatc
    16681 cggtgcagtt gcggctgtgt ctgagctgcg ggcacctcgg ctgctgcgac tcctcgccgc
    16741 tgcggcacgc gacggagcat ttcaaggaga ccggacatcc cgtgatgcgg accttcgagc
    16801 ccggtgagag ctggcgctgg tgcttcgtcg accacgtact ggcgtgaccc acggcccgga
    16861 cggttcgacc gtctgacgcc tgggtacgtc aacccggcgc gcgctcttcc tatttgggcc
    16921 cgcagacctc tagccactgt gcgtactcat aggcttacta tgagtgacag caagggacgg
    16981 ggtccccagg acagaaaagt tgggagcgcg gtagcgtcac cgctgaacca cctagcgcgt
    17041 taccccgggg ggcgaccctc ggcccccgaa aagagctcga aagagcttgt accaccttgg
    17101 aggtgagggt gtcccagatc gcaggcgagc ccgcgacgaa ggacttcgtg gaagtccggc
    17161 tgccggccgc gggtgcctac ctgtcggtgc tgcgtacggc tacggccggt ctcgcggccc
    17221 gtttggactt caccctcgac gagatcgagg acctccgcat cgcggtggac gaggcctgcg
    17281 cgattctgtt gcagcaggcc gttcccggat cggtgctcag ctgtgtcttc cgactcatcg
    17341 acgactcgct cgaggtgacg gtctccgctc cgaccaccga tggtcacgct ccgtcacggg
    17401 acacgttcgc gtggaccgtc ctgtcggcgc tcgcgggcaa ggtcgactcc accgtcgccg
    17461 aggacaagac cgtttcgatc agcctctaca aacagcgcgg cgcgggaccc gggccggcgt
    17521 gaggaacggg gacgggccgg tgcgggacga agagcgcggc acacgggagc ttcccgccgg
    17581 acgcgtcgac ggcctcgacg ggccgcggcg cgcggtggag ggcgtcgacg gcatccccga
    17641 acaggcccgg ccgcacccgg aggacgcaca ggagagcctc tccggccagg acgacgggca
    17701 acgggatccg gagggtgccg cgccgagcac gtcctcggaa gggcggcggc tggtgacggg
    17761 cgggactatg agcgagcacg agcgacacga caagccaggg gtgcagagcg tgcagggcac
    17821 gcagcacggg ccgagcgccc agcacatcca gcacgacccg caggaccgca gcggcgcgcg
    17881 ggcgatgttc atcgagctgc gcaagctgca ggacggcagc gcggagtacg cggagctgcg
    17941 caatcagctg gtccgcatgc acctcccgct cgtcgagcac ctcgcgcgcc gcttccgcaa
    18001 ccgcggtgag ccgctggacg acctcaccca ggtcgcgacc atcggcctga tcaagtcggt
    18061 cgaccgcttc gacccggagc gcggcgtcga gttctcgacg tacgcgactc cgacggtcgt
    18121 cggtgagatc aagcggcact tccgcgacaa gggctgggcg gtgcgggtgc cgcggcgcct
    18181 gcaggaactg cgcctggccc tgacgacggc gacggccgag ctgtcgcaac agcacgggcg
    18241 ctctcccacg gtccacgagc tggccgagaa gctggctatc tcggaggagg aggtcctgga
    18301 gggcctggag tccgccaacg cgtactccac gctgtcgctg gacgtccccg acacggacga
    18361 cgagtccccg gcggtcgcgg acacgctggg tgcggaggac gaggccctgg agggcgtcga
    18421 gtaccgggag tcgttgaagc ccctgctcga ggacctcccc ccgagagaga agcggatcct
    18481 gctccttcgc ttcttcggca acatgaccca gtcgcagatc gcacaggagg tcggcatctc
    18541 ccagatgcac gtctcccgcc tgctggcccg caccctcgcc cagctccgcg aaaagctcct
    18601 ggtcgaggag taaccgggca gccgccgagc gggggcgtcg ccacggagtc cccggtaggc
    18661 ggacgagccc agccctccgg gcgcggatcc cgccttctca gcgggcgcgc aaccggtgtg
    18721 gaccccgccg gcaggccgca gctacttggt ttcctcggcg gcaccggggc cacggatgcc
    18781 cagcgcccgg gtggtctcgg aattgacgag caggaccagc gccgtgatcg cgaccgccgc
    18841 gagggcgatt ccggcgggga tcgccacgct gtccgcctgg agcaggctgt aggcgacggg
    18901 cagcgccatg atctgggtga tgaccgcggg cccccggctc cagctgcggc gcagcagcag
    18961 gccgcgggcg gccagcaggg gcagcagcgc gagcacgatc agcgtcacac ccagggtcac
    19021 gccctgctgc cggtctcccg agtcacccgt agcccccagg acgagcatcc acacgccccc
    19081 cacggcgagg accagcccct ccagcgcggc cagcgcggcc gcggcggtca gccgtccggg
    19141 acggggctct gcggaggggg cgtcaggggt ggggatctgc tcagcgctca cccccgaagg
    19201 gtatccctcg ggccccggcg cgcggcccga ccccggccgc caccccaccg cctcccgcac
    19261 ctcaccgtgt cgagactcac gcccctatct cttaccggat ccctaactct gtctgggacc
    19321 agtacccctc ggtaggtacg ctgcatcgca tgcgtgcact tctcgtggtc aatccggcag
    19381 ctaccaccac aagtgcgcgc acgcgcgatg tcttgatcca cgcgctggcg agcgagatga
    19441 agctcgaggt ggtcacgacc gagtaccgcg ggcacgcccg ggacctcggc cggcaggccg
    19501 cggagagcga cgacatagaa cttgtggtcg cactcggcgg cgacggcacc gtcaacgagg
    19561 tcgtgaacgg tctcctgcac aacggccccg acctggaccg tctgccccgc ctcgcggtgg
    19621 tccccggcgg ctccaccaat gtcttcgccc gcgccctggg cctgcccaac gacgccgtgg
    19681 aggccaccgg cgccctgctg gacgcgctca gagaggaccg cgagcgcgcg atcggcctcg
    19741 gtctcgccgc gggcaccccc ggcaccgagg acgaatccgt cccctcccgc tggttcacct
    19801 tctgtgcggg actcggcttc gacgcggggg tgatcggccg ggtcgaacag cagcgcgagc
    19861 gcggcaagcg ttccactcat gccctctatt tgcgccaagt ggcacgtcag tttttggacg
    19921 aacctcaccg caggcacgga acgatcacac tggatcagcc cggccaggac ccggtcaccg
    19981 atcttgtgat gtccataatc tgcaacacct cgccctggac gtttctcggc aatcgtccgg
    20041 tgtacgcgtc acctaaggct tcgttcgata ccgggctcga cgtactcgct ctcaaccgca
    20101 tgtcgacggg cgcggttgcc cggtatgcca cccagttgct cacttcgtcc cccgagcgcg
    20161 gaccccacgg caagcacgcc ctgtccctgc acgacctgac cgacttcacc ttgcattcga
    20221 aggcgccgct ccccctccag atggacggcg accacctggg actgcgcact agcgtgacgt
    20281 tcacaggcgt acgccgtgca ctgcgtgtga ttgtgtgagc ggaagggccc aaagtccttt
    20341 cactcgaacg tttagaccag ggtccacccc atggaagtac ggctgtgacc tagtcgacac
    20401 cgaggaatca aaaaaaactt tccagaaggg gttgtatccg ccgctgaggt ttgcgagtct
    20461 ctacgtggcg atcgggacgg cccgcaacat cggccccaca gagagccaga acccctcctc
    20521 aaatcacagg accacgtcag gtaatcctgg cagtcggccc ttcacttgtt gagggattcg
    20581 tgaaagcgtt cacattcaca agcaacgtgc atgtaatacc aaggagaggt agcagccatg
    20641 gactggcgtc acaacgccgt ttgccgcgag gaagaccccg agctcttctt ccccatcggc
    20701 aacaccggtc ctgcgctgct gcagatcgag gaagccaagg ccgtctgccg ccgctgcccc
    20761 gtcatggagc agtgcctgca gtgggcgctc gagtccggcc aggactccgg cgtctggggt
    20821 ggcctcagcg aggacgagcg ccgcgcgatg aagcgccgtg ccgcccgcaa ccgggcccgt
    20881 caggccaccg cctgacaccc caccccgtaa cgagcctgag cccggcggcg cgtacagcga
    20941 gtacgcatct cccgcccccg agccgcagcg cgcagtaccc ccgatgcgca tagcaacgta
    21001 agcagtggcc ccggaccttc tggtccgggg ccactgtcat gcgcgac
//
