LOCUS       NZ_BMUQ01000018        38790 bp    DNA     linear   CON 02-SEP-2024
DEFINITION  Streptomyces mirabilis strain JCM 4551 sequence18, whole genome
            shotgun sequence.
ACCESSION   NZ_BMUQ01000018
VERSION     NZ_BMUQ01000018.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptomyces mirabilis
  ORGANISM  Streptomyces mirabilis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wu,L. and Ma,J.
  TITLE     The Global Catalogue of Microorganisms (GCM) 10K type strain
            sequencing project: providing services to taxonomists for standard
            genome sequencing and annotation
  JOURNAL   Int J Syst Evol Microbiol 69 (4), 895-898 (2019)
   PUBMED   30832757
REFERENCE   2  (bases 1 to 249318)
  AUTHORS   Sun,Q. and Ohkuma,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2020) Contact:Qinglan Sun Institute of
            Microbiology, Chinese Academy of Sciences, WFCC-MIRCEN World Data
            Centre for Microorganisms (WDCM); No. 3, yard 1, Beichen W Rd, Ao
            Yun Cun, Chaoyang, Beijing, Beijing 1000101, China URL
            :http://www.wdcm.org/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: gcType assembly pipeline
            Genome Coverage                   :: 117X
            Sequencing Technology             :: Illumina HiSeq X Ten
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_014650275.1-RS_2024_09_02
            Annotation Date                   :: 09/02/2024 04:52:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,311
            Genes (coding)                    :: 9,898
            CDSs (with protein)               :: 9,898
            Genes (RNA)                       :: 81
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 414
            CDSs (without protein)            :: 413
            Pseudo Genes (ambiguous residues) :: 0 of 414
            Pseudo Genes (frameshifted)       :: 172 of 414
            Pseudo Genes (incomplete)         :: 329 of 414
            Pseudo Genes (internal stop)      :: 40 of 414
            Pseudo Genes (multiple problems)  :: 115 of 414
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 210528
            Orig. end                         :: 249318
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BMUQ01000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..38790
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /tool="antismash"
     cand_cluster    1..38790
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..38790
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[35000:37483](-)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 720.7; E-value:
                     9.4e-220)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 400.805"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 442.841"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      complement(35001..37483)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 720.7; E-value:
                     9.4e-220)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 400.805"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 442.841"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     gene            complement(130..1359)
                     /locus_tag="IE289_RS35805"
                     /old_locus_tag="GCM10010317_073880"
     CDS             complement(130..1359)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673819.1"
                     /locus_tag="IE289_RS35805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073880"
                     /product="HTTM domain-containing protein"
                     /protein_id="WP_190172702.1"
                     /transl_table=11
                     /translation="MNRIAVSISRGIARVTDAALGPYQTAVIRIGFAATWLLFLLREFP
                     HRQEMYGPDGPWKWDLAQRLVADNHAFTILMWSDSQVWFETVYALAVLSALLLLVGWRT
                     RTMSVLFMVGVLSLQNRSIFMGDGGDNVIHLMAIYLVFTRCGQVWSLDARRARLTREAR
                     ARGDLPQAGAKDRVGLVLWAALGLLLAAATGAGRLSPGWLAIFWGLWAVQALWWAVGRL
                     ARTVEPRILLDVIANAVHNAALLVIMAEACLIYATAGWYKIQGSRWQDGTAVYYPLHLD
                     YFSPWPALSDLLASHGTIVMLVTYGTVAVQVAFPFTLINRRVKNVLLAAMMTEHAVIAV
                     VLGLPFFSLAMIAADAVFLPTSFLRRLGGWAARARGRLFPPGARKLPGQRAQGPRTPEP
                     AEDPHVGFTA"
     gene            complement(1356..2294)
                     /locus_tag="IE289_RS35810"
                     /old_locus_tag="GCM10010317_073890"
     CDS             complement(1356..2294)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119449.1"
                     /locus_tag="IE289_RS35810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073890"
                     /product="DUF5819 family protein"
                     /protein_id="WP_190172703.1"
                     /transl_table=11
                     /translation="MDAYDEGSKARHLPDGPDGSLPEGPASAGSTPDSTPSADQESVGQ
                     ESVGQESTDQESVPQHHDSQAPTAQAPGPQALGPQAPAADPPVPVPTPTGIASLPLRSQ
                     VVAALALAVVAVVACVHLGMVFLHVAPSNTVTKQHGRAIDDWIYPEFEQNWKLFAPNPL
                     QQNIDVQVRAQVRGADGGITETGWYDLSALDGAAIDGNLLPSHTQQNELRRAWDFYIGT
                     HDNDNRPVGLRGDLSQRYLRRIVVLRLDREGAGVKGAVVESVQVRSRTTNVPPPKWSEE
                     QVSDTPVLRELPWWTVPEEDVTDARTEASAG"
     gene            2661..3794
                     /locus_tag="IE289_RS35815"
                     /old_locus_tag="GCM10010317_073900"
     CDS             2661..3794
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119455.1"
                     /locus_tag="IE289_RS35815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073900"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_190172704.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 8.7e-15, bitscore:
                     49.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.7e-21, bitscore:
                     69.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTFTEEQQAAVEAAKAVFGGVAPDGVPSPAITAGAVADDFDRA
                     LWTKLADADLLSLLLAAEYGGAGLDAIALCLVLREAAKVLARVPLLESSAAAVAVQAYG
                     GEELKAELLARAGRGEVVLTVAANGRTGHDPAELAVTARRDGDAWVLDGVQTAVPWAEN
                     ADFTVVPAHTGAGRTVLALVPRVHEGVVLGEQISTTGERLGELRLESARITAREVIDAD
                     GAWEWLRELLATGTCALALGLGERVLAMTSAYTGKREQFGFPVATFQAVAVQAADRYID
                     LRAMEATLWQAAWRISTGAGGALPASGDVAVAKIWASEGVRRVVQTAQHLHGGFGADVD
                     YPLHRYHAWAKQLELSLGPAAAHEEALGDLLAAHPLG"
     misc_feature    2662..2676
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            complement(3991..4320)
                     /locus_tag="IE289_RS35820"
                     /old_locus_tag="GCM10010317_073910"
     CDS             complement(3991..4320)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019055193.1"
                     /locus_tag="IE289_RS35820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073910"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_054237233.1"
                     /transl_table=11
                     /translation="MPTVEVGDLADGDFLLDVREDDEWQAGHAAGALHIPISEFVARYG
                     ELTEAAPQDGRVHVICRSGGRSAQVTMYLVQQGIDAVNVDGGMQVWAAAGRPVVDDKGT
                     PGFVL"
     gene            complement(4410..5309)
                     /locus_tag="IE289_RS35825"
                     /old_locus_tag="GCM10010317_073920"
     CDS             complement(4410..5309)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381380.1"
                     /locus_tag="IE289_RS35825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073920"
                     /product="hypothetical protein"
                     /protein_id="WP_229889364.1"
                     /transl_table=11
                     /translation="MTTPEAEHSESDRTQAEDARPQGAGDADAHDESAPEAAPEPQARP
                     EERLERAVRAAEQALIEFEIAVETFRVEVENFSRLHHQKLGPMYSRLDELDAQIAEAVA
                     ARTGDVEDIRKADEARARVMPMPGVEELFHGWMDSEGLFPEAVAMLTDQSVRPPQRVRP
                     SDEARQLYRELVRKAHPDLAQDDDERSRRDEFIARVNAAYSRGDEALLRELSEEWAAGP
                     VPEEWKPSRSEELYARLEWLTQRKELLTLVARELEESAIGAMLKMAPEDPDRLLDEIAE
                     QLLAQVDEREKELARLVG"
     gene            complement(5494..6861)
                     /locus_tag="IE289_RS35830"
                     /old_locus_tag="GCM10010317_073930"
     CDS             complement(5494..6861)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825460.1"
                     /locus_tag="IE289_RS35830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073930"
                     /product="DUF2252 domain-containing protein"
                     /protein_id="WP_190172705.1"
                     /transl_table=11
                     /translation="MRGFAGRPVQAAPKEEGKALRRRVPRGVHAELSFDAGRPDAVTAV
                     EESNLGRIPELTPIRVGRMAATPFAFLRGSAGLMAYDLARTPATGIAAQICGDAHAANF
                     GLYGDARGGLVIDLNDFDETAHGPWEWDLKRLATSLVLAGREAGADEDTCRKAAHDAVG
                     AYRRTLRLLAKLPVLDAWNAIADEELVSHADAHDLLGTLERVMEKARANTSGRFAAKST
                     QPTEDGSHRFVDAPPVLRRVPDAEAAAVAASLEHYLTTVSEDRLPLLARYAVHDVAFRV
                     VGTGSVGTRSYVVLLLDHRGEPLVLQVKEARASALLPHLATAGHAIPEVPHEGRRVVLG
                     QKRMQVVSDILLGWTTVEGRPFQVRQFRNRKGSVDPAALAADQVDDYARMTGALLARAH
                     THTADPRLIAGYCGKSEELDESIASFAVAYADRTEADHAELVAAVREGRLAAELGV"
     gene            complement(7187..7558)
                     /locus_tag="IE289_RS35835"
                     /old_locus_tag="GCM10010317_073940"
     CDS             complement(7187..7558)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985770.1"
                     /locus_tag="IE289_RS35835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073940"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_060900223.1"
                     /transl_table=11
                     /translation="MPEPGTHDAGPCQRVDDGMARVFQLLGKRWTGLVVAVLLPHPAHF
                     ADLRRAIPGISERMLSDRLTELGAAGLVVREVDEGPPLRVVYGLTEAGAALQPALVELG
                     TWAEKHLPGSPPCPGELRK"
     gene            7662..8315
                     /locus_tag="IE289_RS35840"
                     /old_locus_tag="GCM10010317_073950"
     CDS             7662..8315
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073540.1"
                     /locus_tag="IE289_RS35840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073950"
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="WP_075033392.1"
                     /transl_table=11
                     /translation="MATLLHVDSSVFPGAASASRTVTDAFRKAWEEQHPQGTVIYRDLA
                     VNPVPHITADAHTAGFAPADAHTPEQAAAFAERLTFIEELEQADAILIGAPMYNFTIPS
                     TLKAWLDQVILIGRTAMSEDSKIKGTPVTVVASRGGSYAPGTPREGYEYVQNYLEAILR
                     DTLALDVHVIVPELTMAPHNPAMADLIPMYEASRAKAVDEAVTKAKEFAERFAA"
     gene            complement(8503..9345)
                     /locus_tag="IE289_RS35845"
                     /old_locus_tag="GCM10010317_073960"
     CDS             complement(8503..9345)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976615.1"
                     /locus_tag="IE289_RS35845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073960"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_190172706.1"
                     /transl_table=11
                     /translation="MIVVTGATGNVGRPLIEALAEAGEQVVAVSRRPLPSPTDGVRHAQ
                     ADLGSAESMRPVLEGADAFFILLAGELLGYGEAATDLLAAAGDAGVKRVVLLSSQINAT
                     RPDSASHGRLREFEEAVRGSGLDFTILRAGGFASNAFAWAESVRADRTVFAPFGDVALP
                     VVDPADIAAVAAVVLREDGHAGRTYEVTGPEAVSPRAQAEVIAGAIGEEVTFVELTREA
                     AHTHLAQFMPEDVIPGTLDILGAPLPAEQRVSPDVEKVLGRPATPFSGWVSRSLPAFK"
     misc_feature    9337..9350
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.05"
                     /tool="antismash"
     misc_feature    complement(9340..9354)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.1"
                     /tool="antismash"
     misc_feature    9341..9354
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.86"
                     /tool="antismash"
     gene            complement(9473..10507)
                     /locus_tag="IE289_RS35850"
                     /old_locus_tag="GCM10010317_073970"
     CDS             complement(9473..10507)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385274.1"
                     /locus_tag="IE289_RS35850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073970"
                     /product="YafY family protein"
                     /protein_id="WP_190172707.1"
                     /transl_table=11
                     /translation="MKADRLVATLLLLQARGRVTVREVAQELEVSERTARRDLEALTTA
                     GVPVYSQRGRGGGWSLVGGARTDLTGFTSREIGALFLAAGPLSASPELRAALRKLMRAV
                     PAPMRPHAEAAAKAILIDGVDWSRTAGGGGPHQHTLERAVLDGEQVRLGYAHPDRAPGE
                     RTVHPLGLVSKAGRWYLVAGTEEGLRTFRLSRVTSATRTGEPVRRPEGFDLAAAWRELA
                     AEVEQRLTAATVRARADRDALPVLRQLLGGRLRTGEAQIDGRVEFTADGPSVEVLAAQL
                     AGLGSRVEVLDPPEARESLVRLGRSLTAVYGGREKETHLDSHFPLGTYYTEDASVPVMA
                     AHHG"
     misc_feature    complement(10217..10219)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10580..10593
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.78"
                     /tool="antismash"
     misc_feature    complement(10580..10596)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.12"
                     /tool="antismash"
     misc_feature    complement(10586..10600)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.41"
                     /tool="antismash"
     gene            10671..11273
                     /locus_tag="IE289_RS35855"
                     /old_locus_tag="GCM10010317_073980"
     CDS             10671..11273
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385273.1"
                     /locus_tag="IE289_RS35855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073980"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_190172708.1"
                     /transl_table=11
                     /translation="MADSTNPPANPPTDPRGGLFKAVELTGRTLAALRPEQYDTVTPCP
                     DYSVRDMANHVVSVLRRVAVMGAGGSFMSVPHFAQDVPDGDWAKAWAEATKEFDAVWSD
                     PAVLGRQIGLPWGPVPGVVASVIYTNEFVLHAWDLAKATGQSPEWDPEMLAAPLANMHR
                     AVPAEPRGGQVPFGPVVEVHEDAPDIDKLVGWYGRRP"
     gene            complement(11426..12937)
                     /locus_tag="IE289_RS35860"
                     /old_locus_tag="GCM10010317_073990"
     CDS             complement(11426..12937)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010352239.1"
                     /locus_tag="IE289_RS35860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_073990"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_099921673.1"
                     /transl_table=11
                     /translation="MITRRALIGAGTAAVGLAVLPNSPVSAGSSAPWSTLAGKLQGQLV
                     LPTDSGYGVAKQLELGQFDSVNPRAVAYCVSSSDVSVALRFAQDNGLPSAVRSGGHSFA
                     GYSTTPGLIIDVSRLNAITVGNGTVDIGPGAKNVEILNALAPHALVVSEGGCPTVSAGG
                     FLQGGGFGFLTRPTGMACDAITSAEVVLADGCVVTASPTSHPDLFWAIRGGGGGNFGVV
                     TRFTVTPHEGDQMAISNLIFPYDRAADVLHGVGQWLVDAPRTIGGGAYLVQADAAPGTV
                     PALNVFLASRGTPAELASEAARLLSLTGAVTARQDAVMTYQQVMMMIFGCSTLTQDQCQ
                     RAGKSPSGVLTRPSFGLERTRLGSAPYAQSDWANVVTAFDADRKAGQARYLDFHFFGGA
                     ANDPARTDTAYVHRDSLFSVNYRVLINDPAQVTAEATAVATSWVDHGFDTIDPLSNGET
                     YQNWMDAELPNWRQSYYAENYARLKVVKAKYDPYRYFKFAQGIGA"
     gene            complement(13134..14834)
                     /locus_tag="IE289_RS35865"
                     /old_locus_tag="GCM10010317_074000"
     CDS             complement(13134..14834)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     conventional flavin-dependent halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_functions="biosynthetic-additional (t2pks) HAL
                     (Score: 414.8; E-value: 9.7e-127)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385271.1"
                     /locus_tag="IE289_RS35865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074000"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_099921674.1"
                     /sec_met_domain="Trp_halogenase (E-value: 4.4e-07,
                     bitscore: 22.9, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTKAEEAKKADKAAEWTECDVAILGSGLAGSIMGAILARQGANV
                     VLIDAGQHPRFAVGESQNPQLVEWLHILAVRYDVPEIKHMLDVKAVTEHIGPTHGRKQS
                     FGFVTHRPNREPDPHEATMFVIPKMLTEAVHLFRQDTDSHYLNVAAKYGCTLRQNWFAT
                     DLDVDDDGVTITGRNGEVFRAKYLIDASGFRSPLAQKFDLRENPPRHKHHARSLFTHYV
                     GIKPYDDVCNYPEALRPPAESPFHGGTLHHLIERGWFWIIPFDNYKDSKNPACSVGLTF
                     DERLYPKPKDMTPDQEFNHYLDMYPAVKRQFEGAKRIREWVSTDRLQYSSKRTIGARWC
                     LMSHAAGFIDPLYSRGLSNTFEVVDALAYRILDALREDDFTEERFEYVERLEQGLLEYN
                     DKIVNSSYIAFSHFRLWNAVFRVWACFTTPATMRQIMARQNFQLDGDDRHFKEMEKAPY
                     TGLWWPDSHAFKVLFDTTAETCERYEAGEIDGDKAADIVFEAIRDCESVNTPFGWKGPE
                     DLRFFRATTPTMMKFMWWASTSGPKEMRDLGRSMLAGVVKQGVRGRKVS"
     gene            complement(14945..16420)
                     /locus_tag="IE289_RS35870"
                     /old_locus_tag="GCM10010317_074010"
     CDS             complement(14945..16420)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 529.2; E-value: 2.3e-161)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037168.1"
                     /locus_tag="IE289_RS35870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074010"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190172709.1"
                     /transl_table=11
                     /translation="MDAFNADVIVAGAGPSGLMLAGELRLSGLSVIVLDRLEQPMQQSR
                     ALGFSARTIEEFGQRGLLEDFGPLETIPGGHFGGLPIDYRIVEGGNFGVRGVPQSRTEA
                     IINKWAVGLGADVRRGHEVIGLTQDENGVQVEVAGPEGVETLRAAYVVGCDGARSTVRH
                     LAGIDFPGVSATIEMKMADVAGVQLRLRPTGEVGEAGMVVVLPLGPGATRVVVFERGAG
                     VRPTQEPPTFEEVAAAFQRVTGEDISGAKQLWTSYFTDASRHAAEYRKGRVFLAGDAAH
                     IHLPIGAQGISAGVGDVVNLGWKLAAAVKGHAPEGLLDTYHSERHPVGARIVYNTLVQR
                     TLYLGGPEAQPLRDLFAELVQIEDVRRHLVGLVTGLDITYGAVEGGHPLLGRRLPDQEL
                     LVGDEKTTTYELLHQGRPVLLDLHDNAALREAAAAWSDRVDVVTATRPDAAAPAADLLV
                     RPDGYIAWVGADGSTDGLTDALAQWFGEPGTAA"
     misc_feature    complement(16433..16451)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.31"
                     /tool="antismash"
     misc_feature    complement(16496..16511)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            complement(16646..17041)
                     /locus_tag="IE289_RS35875"
                     /old_locus_tag="GCM10010317_074020"
     CDS             complement(16646..17041)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524785.1"
                     /locus_tag="IE289_RS35875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074020"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_095853649.1"
                     /transl_table=11
                     /translation="MSQPLPLSAAAEEFLAENALCTLTTLRPDGTPHVAPVRFTWDGEA
                     GLARVMTTVHRRKSRNLLARAGGRAAVCQLVGPRWITLEGPATVSTDPPRVVEGMRRYA
                     KRYWSQPPQPPGLAVIEIAVDRVMGLY"
     misc_feature    complement(16853..16855)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17089..18582)
                     /locus_tag="IE289_RS35880"
                     /old_locus_tag="GCM10010317_074030"
     CDS             complement(17089..18582)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385268.1"
                     /locus_tag="IE289_RS35880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074030"
                     /product="MFS transporter"
                     /protein_id="WP_190172710.1"
                     /transl_table=11
                     /translation="MSIQESTHSPAQAAGESGPVRRPGLILAFLCLAGFMTFLDVSIVN
                     VALPTIEDELNISTTALQYVVTTYGMLLGGFLLLTGRLADTLGRRRMLQTGLLLFAGSS
                     LLAGVSQNAAMLIGARGAQGLGAAFIATAALSLLTNNFEEGAARNKALGAWGALSGLAA
                     VAGVTLGGLLTDGPGWRWIFFINVPIGVIGALVAPMVVGESRSAQRSKSFDVAGAVTLT
                     AGLVLLIFTLGQTVSDSNVPTGRVVGGFILSAILLVSFIVIERRAKEPLMPLGIFRRPS
                     LRAANGIAILLLGTCVTLFFFASLFMQQVLDYSAVKTGFAYVPLAVLTAVGAGVASQVV
                     TKVAAKPVLLVGLALAATGMMLLWRAPSDASYLTDVLPAFVLMGLGLGMSFVPLQVSAF
                     AGIEERESGLAAGLINTAQEVGGALGLAVAATYAFRRVDELTAKAHGVPALVQEARTTV
                     FHDAFLVGACFAAAAFVVTLVLLPFTRSSEQSAAVPAHA"
     gene            18789..19196
                     /locus_tag="IE289_RS35885"
                     /old_locus_tag="GCM10010317_074040"
     CDS             18789..19196
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891503.1"
                     /locus_tag="IE289_RS35885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074040"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_075033417.1"
                     /transl_table=11
                     /translation="MTSPEAAHAAAAGTPQRCPIAPVLDIVFSRWTTPILWTLNAFGTQ
                     RFVELHRNIGTITPKVLTQRLRQLERDGLVIRTYYPEVPPRVEYEISDLGRTLAPLFAS
                     LFDWSTGHLPLVEQARQAFDEAEEQAAARNH"
     gene            complement(19211..19735)
                     /locus_tag="IE289_RS35890"
                     /old_locus_tag="GCM10010317_074050"
     CDS             complement(19211..19735)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115982.1"
                     /locus_tag="IE289_RS35890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074050"
                     /product="flavin reductase family protein"
                     /protein_id="WP_225900379.1"
                     /transl_table=11
                     /translation="MIPVSQAIPEQLGPVDGRALRTVCGHFATGVTVITSGSGDNATGA
                     TVNSFTSVSLDPALVLICLHDNSRLLPVVQESGGFVVNFLTQRQEPVAWAFAGRRTARI
                     EEVPHHRSVLDLPVLSEALAHLECRLVTEYDGGDHTILLGEVVGLRAPSEAEQEDPLIF
                     FQGSMRTPAWS"
     gene            complement(19907..21217)
                     /locus_tag="IE289_RS35895"
                     /old_locus_tag="GCM10010317_074060"
     CDS             complement(19907..21217)
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385265.1"
                     /locus_tag="IE289_RS35895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074060"
                     /product="cation:proton antiporter"
                     /protein_id="WP_190172711.1"
                     /transl_table=11
                     /translation="MTTLAAASPQDMKLAIMLADIGVVLVAGAALGRLAQKLRQPMVVG
                     EITAGVLLGPSVLGLLPGNLTEHLFPADVRPLLSAVSQVGLILFMFVVGWEFEKRLIRP
                     HARLAAGVSLSSIAMAFGLGVALAPFLYDEHSTVAGHHISFVAFATFIGTAMSVTAFPV
                     LARILTENKLLDTRAGSLSLASAAIDDLLAWCLLAYVSALVTANGNYSDLARIGLYSVL
                     YVAGMLLVVRPLVARLVWRWAATERWSALLAVLCAGALTSAWLTTWIGIHAIFGAFLFG
                     FVMPREPAMVLAEHLRKPMDHVSVVLLPVFFIVTGLGVDLGALTAGDFVALVAIIVVAC
                     TGKLVGAILPARLAGFSWRESKDLGLLMNTRGLTELIILNAAVSLGVLDTRMFTMLVIM
                     ALVTTAMAGPLLSRRRPVPAVVPEPSEPSEAPASRAA"
     gene            complement(21214..21660)
                     /locus_tag="IE289_RS35900"
                     /old_locus_tag="GCM10010317_074070"
     CDS             complement(21214..21660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383123.1"
                     /locus_tag="IE289_RS35900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074070"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_190172712.1"
                     /transl_table=11
                     /translation="MQSGPEALEISTLLDRYLIGLDDDELDDAWARGLFTKDALVEFPM
                     SRHEGLDGLAGYHRDALAAFAATQHLGSPAVVDLDDAGERAVLRANLVSTHVHHPDAAD
                     EPLFQVGTLATGEARRAAEGWRLSSLTFRVLWTRGTPPRPREPQ"
     misc_feature    complement(21637..21639)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21909..22604
                     /locus_tag="IE289_RS35905"
                     /old_locus_tag="GCM10010317_074080"
     CDS             21909..22604
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385263.1"
                     /locus_tag="IE289_RS35905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074080"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_190172713.1"
                     /transl_table=11
                     /translation="MPKIAADGQHLTVLNLFSTDAAEKQVKLLAAMRQIVDTAAYEGWI
                     SSTVHAGQDKPGTANFIQWRSTEDLESRYAGEEFKHRTLPLFGEITTSIRLLQNEIAFT
                     QQKPELGGVTEISPSRDDYTAIELFGVLPENQEDLIDALGESQTWLVDVPGYRTHTVLR
                     GLRARGIEGKFVVVYSQWDSKEAYDAFRSAPQGERSPERQKVDARVAALQTWQDENTYQ
                     VVHTRSAGE"
     gene            22924..23877
                     /locus_tag="IE289_RS35910"
                     /old_locus_tag="GCM10010317_074090"
     CDS             22924..23877
                     /NRPS_PKS="Domain: Polyketide_cyc2 (5-138). E-value: 5e-12.
                     Score: 38.4. Matches aSDomain:
                     nrpspksdomains_IE289_RS35910_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (161-298). E-value:
                     1.4e-07. Score: 24.0. Matches aSDomain:
                     nrpspksdomains_IE289_RS35910_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 410.4; E-value: 8.9e-126)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050070.1"
                     /locus_tag="IE289_RS35910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074090"
                     /product="aromatase/cyclase"
                     /protein_id="WP_190172714.1"
                     /transl_table=11
                     /translation="MEHPGMRQVAHEINIAVPADTVHRLIAEVGNWPRIFPSVIHVEYE
                     EAPEGEERLTIWETAPTAAGEPRCRPLRRIVEPAKLRVNFQHLVTASPVAGLGGAWLVE
                     PLGENASRVRLLHEFRTADDDPGALDRIGAEIDRSAVTELAALKENAEREYADAELTFS
                     FEDTVHVDGSAKDLFAFINEANLWSERLPHVATVRLEEDTVGLQTLEMDTRAKDGSVHT
                     TKSYRVTFPHQHIAYKQVTLPALMTLHTGHWTFTDTDQGVAATSQHTVSLNTDNIARIL
                     GDTATVADAREYVHTALSTNSLATLNHAKAHAEGRR"
     aSDomain        22939..23337
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35910_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.00E-12"
                     /label="IE289_RS35910_Polyketide_cyc2.1"
                     /locus_tag="IE289_RS35910"
                     /protein_end="138"
                     /protein_start="5"
                     /score="38.4"
                     /tool="antismash"
                     /translation="MRQVAHEINIAVPADTVHRLIAEVGNWPRIFPSVIHVEYEEAPEG
                     EERLTIWETAPTAAGEPRCRPLRRIVEPAKLRVNFQHLVTASPVAGLGGAWLVEPLGEN
                     ASRVRLLHEFRTADDDPGALDRIGAEIDR"
     aSModule        22939..23817
                     /domains="nrpspksdomains_IE289_RS35910_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_IE289_RS35910_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="IE289_RS35910"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        23407..23817
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35910_Polyketide_cyc2.2"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.40E-07"
                     /label="IE289_RS35910_Polyketide_cyc2.2"
                     /locus_tag="IE289_RS35910"
                     /protein_end="298"
                     /protein_start="161"
                     /score="24.0"
                     /tool="antismash"
                     /translation="FSFEDTVHVDGSAKDLFAFINEANLWSERLPHVATVRLEEDTVGL
                     QTLEMDTRAKDGSVHTTKSYRVTFPHQHIAYKQVTLPALMTLHTGHWTFTDTDQGVAAT
                     SQHTVSLNTDNIARILGDTATVADAREYVHTAL"
     gene            23874..24680
                     /locus_tag="IE289_RS35915"
                     /old_locus_tag="GCM10010317_074100"
     CDS             23874..24680
                     /NRPS_PKS="Domain: ACPS (141-184). E-value: 2.4e-08. Score:
                     25.8. Matches aSDomain:
                     nrpspksdomains_IE289_RS35915_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013786.5"
                     /locus_tag="IE289_RS35915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074100"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_129592043.1"
                     /transl_table=11
                     /translation="MTPTVRRLAVARGELDVWLLPPPDSPRDVPYDELDAYERGRADSY
                     RRPDDRQMYAAAHVGLRRVLAGYTGIEPSRLNLAGERYNGNGERHGRPVVLGVPGGAPQ
                     FSLSHSHGLAIVVVAESRVGADVQRLPSPQTAEACLPALHPAEREELEKIPEHERTMAF
                     GRLWTRKEAYLKGLGTGLTRGADLDYLGEAGLAERPTGWVVGNLPLCSTHIAAVALAGA
                     GDRPVALRAVPTAYLYAPDAVERLVEMEPGLRSMLRDPAQHGDLER"
     aSDomain        24297..24425
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35915_ACPS.1"
                     /evalue="2.40E-08"
                     /label="IE289_RS35915_ACPS.1"
                     /locus_tag="IE289_RS35915"
                     /protein_end="184"
                     /protein_start="141"
                     /score="25.8"
                     /tool="antismash"
                     /translation="ALHPAEREELEKIPEHERTMAFGRLWTRKEAYLKGLGTGLTRG"
     gene            complement(24831..25103)
                     /locus_tag="IE289_RS35920"
                     /old_locus_tag="GCM10010317_074110"
     CDS             complement(24831..25103)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850635.1"
                     /locus_tag="IE289_RS35920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074110"
                     /product="acyl-CoA carboxylase subunit epsilon"
                     /protein_id="WP_075033384.1"
                     /transl_table=11
                     /translation="MSIQRPALVPVPDPAPDPVSEPAAGPLFRIERGCPSPEELAALTA
                     VLMAVTAGPGVAPDDTARKHQVVALWRRPERVTGFDGPRTWRAAA"
     gene            complement(25118..26686)
                     /locus_tag="IE289_RS35925"
                     /old_locus_tag="GCM10010317_074120"
     CDS             complement(25118..26686)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019520922.1"
                     /locus_tag="IE289_RS35925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074120"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_067384835.1"
                     /transl_table=11
                     /translation="MEPAIPIELGGRLMELAERKDIARAGQDPKATERQHAKGKLTAHE
                     RIELLLDKGSFQEVEPLRRHRATGFGLEAKKPYGDGVITGWGTVEGRTVFVYAHDFRVF
                     GGALGEAHACKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVSALAGYGGIFQRNTRASG
                     VIPQISVMLGPCAGGAAYSPALTDFIFAVRDISQMFITGPDVVRAVTGEEISQNGLGGA
                     DVHGAVSGVAHFVHDDEESCLAEVRYLLSLLPSNNRELPPRHVSGDPGDRSGDVLLDLV
                     PHDGNRSYDMRGVVEELVDDGDYVEVHAGWAPNIVCALARIDGHTVGIVANQPAAMAGV
                     LDIKASEKAARFVQFCDSFNIPLVTLVDVPGFLPGVDQEHEGIIRRGAKLLYAYCNATV
                     PRVSVVLRKAYGGAYIVMDSRSIGADIALAWPTNEIAVMGAEGAANVVFRREIAAADDP
                     DAMRQEKIDQYKEELVHPYYAAERGLVDDVIDPRETRAVLARSLAMLAAKHAELPRRKH
                     GNPPQ"
     gene            complement(26732..27046)
                     /locus_tag="IE289_RS35930"
                     /old_locus_tag="GCM10010317_074130"
     CDS             complement(26732..27046)
                     /GO_function="GO:0000035 - acyl binding [Evidence IEA]"
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_PP (21-104). E-value: 1.3e-10.
                     Score: 33.5. Matches aSDomain:
                     nrpspksdomains_IE289_RS35930_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.5"
                     /locus_tag="IE289_RS35930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074130"
                     /product="acyl carrier protein"
                     /protein_id="WP_054237216.1"
                     /sec_met_domain="PP-binding (E-value: 3.8e-06, bitscore:
                     21.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPLSDDTPCSWLDRLPDPVQLRAMAPDARARTIGHCLRLELHDL
                     LAVPPGHRLSPGLPLRGQGLDTLDALHLGRRIRRALDAEVPAEVLRESTVGELTALLAR
                     "
     aSDomain        complement(26735..26983)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35930_PKS_PP.1"
                     /evalue="1.30E-10"
                     /label="IE289_RS35930_PKS_PP.1"
                     /locus_tag="IE289_RS35930"
                     /protein_end="104"
                     /protein_start="21"
                     /score="33.5"
                     /tool="antismash"
                     /translation="LRAMAPDARARTIGHCLRLELHDLLAVPPGHRLSPGLPLRGQGLD
                     TLDALHLGRRIRRALDAEVPAEVLRESTVGELTALLAR"
     gene            complement(27030..28394)
                     /locus_tag="IE289_RS35935"
                     /old_locus_tag="GCM10010317_074140"
     CDS             complement(27030..28394)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037170.1"
                     /locus_tag="IE289_RS35935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074140"
                     /product="MFS transporter"
                     /protein_id="WP_190172715.1"
                     /transl_table=11
                     /translation="MTTTRPDARDTTKRARRGRRGRRPGGVGSRRTPFRSLAVRNFRLF
                     AAGQVVSVAGTWMMVTAQDWLVLSLTGDSGTALGTVTALQFTPLLLFTLYGGRLADRHD
                     KRLLLTVANLVSGALALALAVLVLAGSAQLWQLYLFALGLGTVNAVEVPTRMAFVSEMV
                     GPELLPNASALSAAYFNTARVVGPALAGLLISAVGAGTAMLLNAASYLATVTGLRLMRP
                     GELLRTAPPERGVKVVDGLRYVRGHPDLFVPLALVAVVGLFGFNFQLTLPLLAKTVFHS
                     GATAFGLLTTAFAAGSLLAAFATTVRSARPAALTVTASALAFGLLETAAGWSPTYAWAA
                     VLLFLTGFATLYFAQAANHRIQLGSDAAYRGRVMALYTLILQGLTPLGALLVGWLTVRH
                     GARSGLYVGGLASSAAALAVLLAGRTRRFLPSHRPEPALLGPGPLPERQPHESPE"
     gene            complement(28399..29298)
                     /locus_tag="IE289_RS35940"
                     /old_locus_tag="GCM10010317_074150"
     CDS             complement(28399..29298)
                     /EC_number="3.-.-.-"
                     /NRPS_PKS="Domain: Abhydrolase_1 (33-131). E-value: 9e-09.
                     Score: 27.2. Matches aSDomain:
                     nrpspksdomains_IE289_RS35940_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050076.1"
                     /locus_tag="IE289_RS35940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074150"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_177324387.1"
                     /sec_met_domain="PF00561 (E-value: 7e-07, bitscore: 22.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6e-13, bitscore:
                     43.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSMSPGVRPVALAAGDVTLSALIAQPSGPPRATVVAVHGGGMSA
                     GYFDGQAHPDVSLLALGARLGYTMVAVDRPGYGLSAADAPSGQTLAEQSAALHAALRHL
                     AGRAETGAGVFLLAHSFGGKLALTYAACQAGDPDPAVPPLLGLDISGLGRDYAVDHPEG
                     GPDPHQHRHWKRNWGALRFYPPNTFREAEGLVAPMPPREQAEALQWPRRFPVAAAAVQV
                     PVRLTFAEQELWWHHDEDTVADLAAHFASAPSAAVDRQPGAGHNISLGWAARTYHLRAF
                     AFFEECLARRSAGASVTP"
     aSDomain        complement(28906..29199)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35940_Abhydrolase_1.1"
                     /evalue="9.00E-09"
                     /label="IE289_RS35940_Abhydrolase_1.1"
                     /locus_tag="IE289_RS35940"
                     /protein_end="131"
                     /protein_start="33"
                     /score="27.2"
                     /tool="antismash"
                     /translation="TVVAVHGGGMSAGYFDGQAHPDVSLLALGARLGYTMVAVDRPGYG
                     LSAADAPSGQTLAEQSAALHAALRHLAGRAETGAGVFLLAHSFGGKLALTYAA"
     gene            complement(29463..30938)
                     /locus_tag="IE289_RS35945"
                     /old_locus_tag="GCM10010317_074160"
     CDS             complement(29463..30938)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 588.8; E-value: 1.9e-179)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383113.1"
                     /locus_tag="IE289_RS35945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074160"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_229889365.1"
                     /transl_table=11
                     /translation="MDAQMDADVIVVGAGPAGLMLAGELRLGGVSVIVAERLARPTGQS
                     RGLGFTARAMESFDQRGLVPRFGGLEKSPMGHFGGVQFDYTVLEDAHFGARGVPQSQTE
                     AVLEEWAGELGADIRRGWEFLALEQDGTGVTVTVAAPDGERTLRAAYLVGADGGHSPVR
                     KAAGFDFPGTPATRGMYLADVVGCEIPPRFLGERLPGGMVMAAPLKEGVDRIIVCEHGT
                     PPADRSETPEFAEVAAAWERLTGEDISGGGADWVSSFTDATRQVTEYRRGRVLLVGDAA
                     HIHLPAGGQGLSTGVQDAVNLGWKLAATVQGRAPEGLLDTYHDERHAVGARLLMNTKAQ
                     GTVFLGGPESQPLRDLFAELIGLDSVKRHLAGVVSHLDVRYDLGDTGDSLVGRRLPPRA
                     LNTATGEVRTPELLHAAQGVLLDLADDSVLREAAARWKDRVTVVTGTPQDPAAFGGAAA
                     VLVRPDGYVAWADTGSAELCATLHRWFGAPEAR"
     gene            complement(31122..32780)
                     /locus_tag="IE289_RS35950"
                     /old_locus_tag="GCM10010317_074170"
     CDS             complement(31122..32780)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 533.0; E-value: 1.6e-162)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037166.1"
                     /locus_tag="IE289_RS35950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074170"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_190172716.1"
                     /transl_table=11
                     /translation="MTTDHQDTDTTILDTDVLVVGAGPAGLMLATELRLGGAEVVVVDQ
                     RPGPTTESRASTLHARTMEILDSRGLLDELGTPPCEPRGHFGGVPLDLTLPSSHPGQWK
                     VAQTRTEELLQRRAAVLGADLRRRHQLLSLEAKSEGAGRDEAGRDEAGQAGAGQDRVEA
                     EAIGPYGPVRIRARYLVGCDGEDSTVRRLVRAPFPGRDAARELLRADVSGVEVADRRFQ
                     RLEHGLAIAATREGVTRVMVHEFGRPAAERGGAEPDFAEVTDVWKRVTGEDISQGTPLW
                     VNAFGDANRQLAHYRHGRVLFAGDAAHRQMPSGGQALNLGVQDAFNLGWKLAAVVRGSA
                     GEDLLDTYHSERHTVGRQVLANIRAQVELLLGGPEVEPARALLTELVALDGVRQHLAGM
                     ISGLGIRYDVEGVEGYGAGGVGGDDFGAGAAKGVGVGPEIHSDEHPLLGRRLPDAWLEP
                     AECGARRRTTELLRTGRGLLLSLDGDGAPALRATAAPWSDRVAFVADRPAAGGPLPAGQ
                     ALLVRPDGHVAWAGSGPAGLARALTRWFGTPAADD"
     gene            complement(32783..33718)
                     /locus_tag="IE289_RS35955"
                     /old_locus_tag="GCM10010317_074180"
     CDS             complement(32783..33718)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-146). E-value:
                     2.3e-16. Score: 52.4. Matches aSDomain:
                     nrpspksdomains_IE289_RS35955_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (155-307). E-value:
                     1.2e-08. Score: 27.4. Matches aSDomain:
                     nrpspksdomains_IE289_RS35955_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 499.7; E-value: 5.8e-153)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389974.1"
                     /locus_tag="IE289_RS35955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074180"
                     /product="aromatase/cyclase"
                     /protein_id="WP_054237214.1"
                     /transl_table=11
                     /translation="MTTREVEHEITIAAPAPAVYRLLAEVTNWPRIFPPTIHVDRVEHD
                     GSQERIRIWATANGEAKNWTSRRELDPEALRITFRQEVTAPPVAAMGGTWIIEPLGENE
                     SRVRLLHDYRAVDDDPHDLLWIDEAVDKNSRSELAALKKNVEFAHAAEEVTFSFEDTVY
                     VDGSAKDVYAFINEANLWSERLPHVATVRLEEDTVGLQTLEMDTRAKDGSVHTTKSYRV
                     TFPHQRIAYKQVTLPALMTLHTGHWTFEDTDQGVAATSQHTVTLNTDNIESILGCGATV
                     ADAREYVHTALSTNSRATLTHAKAFAENRR"
     aSDomain        complement(32798..33253)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35955_Polyketide_cyc2.2"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.20E-08"
                     /label="IE289_RS35955_Polyketide_cyc2.2"
                     /locus_tag="IE289_RS35955"
                     /protein_end="307"
                     /protein_start="155"
                     /score="27.4"
                     /tool="antismash"
                     /translation="FSFEDTVYVDGSAKDVYAFINEANLWSERLPHVATVRLEEDTVGL
                     QTLEMDTRAKDGSVHTTKSYRVTFPHQRIAYKQVTLPALMTLHTGHWTFEDTDQGVAAT
                     SQHTVTLNTDNIESILGCGATVADAREYVHTALSTNSRATLTHAKAFA"
     aSModule        complement(32798..33706)
                     /domains="nrpspksdomains_IE289_RS35955_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_IE289_RS35955_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="IE289_RS35955"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(33281..33706)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35955_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.30E-16"
                     /label="IE289_RS35955_Polyketide_cyc2.1"
                     /locus_tag="IE289_RS35955"
                     /protein_end="146"
                     /protein_start="4"
                     /score="52.4"
                     /tool="antismash"
                     /translation="EVEHEITIAAPAPAVYRLLAEVTNWPRIFPPTIHVDRVEHDGSQE
                     RIRIWATANGEAKNWTSRRELDPEALRITFRQEVTAPPVAAMGGTWIIEPLGENESRVR
                     LLHDYRAVDDDPHDLLWIDEAVDKNSRSELAALKKNVE"
     misc_feature    33717..33732
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.71"
                     /tool="antismash"
     gene            complement(33769..34554)
                     /gene="fabG"
                     /locus_tag="IE289_RS35960"
                     /old_locus_tag="GCM10010317_074190"
     CDS             complement(33769..34554)
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-163). E-value: 2.3e-09. Score:
                     29.3. Matches aSDomain:
                     nrpspksdomains_IE289_RS35960_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 476.7; E-value: 4e-146)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389975.1"
                     /locus_tag="IE289_RS35960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074190"
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="WP_099921683.1"
                     /sec_met_domain="adh_short (E-value: 2.9e-34, bitscore:
                     112.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTLEKRVALISGATSGIGLASARALAAAGHRVFIGARSADNVAE
                     TVKILQEEGIDADGTVLDVRDPASVGAFVQAAVDRFGTVDVLVNNAGRSGGGVTADIED
                     ELWTDVIDTNLNSVFRLTREVLTTGGMRHKSRGRVINIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRAGYAAAYDTSEDAILEKFQAKIP
                     LGRYSTPEEVAGMVAYLASDTAASVTAQAINVCGGLGNF"
     aSDomain        complement(34066..34533)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35960_PKS_KR.1"
                     /evalue="2.30E-09"
                     /label="IE289_RS35960_PKS_KR.1"
                     /locus_tag="IE289_RS35960"
                     /protein_end="163"
                     /protein_start="7"
                     /score="29.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALISGATSGIGLASARALAAAGHRVFIGARSADNVAETVKILQE
                     EGIDADGTVLDVRDPASVGAFVQAAVDRFGTVDVLVNNAGRSGGGVTADIEDELWTDVI
                     DTNLNSVFRLTREVLTTGGMRHKSRGRVINIASTAGKQGVVLGAPYSASKHG"
     CDS_motif       complement(34459..34527)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS35960_0001"
                     /evalue="4.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IE289_RS35960"
                     /protein_end="32"
                     /protein_start="9"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LISGATSGIGLASARALAAAGHR"
     gene            complement(34652..34927)
                     /locus_tag="IE289_RS35965"
                     /old_locus_tag="GCM10010317_074200"
     CDS             complement(34652..34927)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ACP (13-82). E-value: 2e-16. Score:
                     52.1. Matches aSDomain: nrpspksdomains_IE289_RS35965_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 131.3; E-value: 2.3e-41)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385252.1"
                     /locus_tag="IE289_RS35965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074200"
                     /product="acyl carrier protein"
                     /protein_id="WP_054237212.1"
                     /sec_met_domain="PP-binding (E-value: 7.7e-10, bitscore:
                     33.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSEFTLDDLRRILQEGAGVDEGVDLDGDILDEPFEVLGYESLA
                     LLETGSRIEREYGIVLDEDLLTDADTPRALIEAVNQQFGADEPAAA"
     aSDomain        complement(34682..34888)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35965_ACP.1"
                     /evalue="2.00E-16"
                     /label="IE289_RS35965_ACP.1"
                     /locus_tag="IE289_RS35965"
                     /protein_end="82"
                     /protein_start="13"
                     /score="52.1"
                     /tool="antismash"
                     /translation="ILQEGAGVDEGVDLDGDILDEPFEVLGYESLALLETGSRIEREYG
                     IVLDEDLLTDADTPRALIEAVNQQ"
     gene            complement(35001..36215)
                     /locus_tag="IE289_RS35970"
                     /old_locus_tag="GCM10010317_074210"
     CDS             complement(35001..36215)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (68-402). E-value:
                     1.8e-32. Score: 104.7. Matches aSDomain:
                     nrpspksdomains_IE289_RS35970_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 720.7; E-value: 9.4e-220)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037162.1"
                     /locus_tag="IE289_RS35970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074210"
                     /product="ketosynthase chain-length factor"
                     /protein_id="WP_190172717.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.1e-46, bitscore:
                     153.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="t2clf (E-value: 2.8e-214, bitscore: 705.1,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTVVVTGLGIAAPNGLGTQDYWAATRTGKNGIGRVTRFDPSSY
                     PSTLAGEVPGFVAADVLPSRLLPQTDHMTRMALVAAEWALADAGIDPKELPEYDMGVVT
                     ASSSGGFEFGQGELEKLWSQGSQYVSAYQSFAWFYAVNSGQISIRNGLKGPSGVIVSDE
                     AGGLDAVAHGRRLIRKGTPMIVSGGVDASICPWGWVAQMAGDRLSTSDEPTRAYLPFDA
                     DAAGYVPGEGGAILIMESAESACERGAKIYGEIAGYGSTFDPRPGSDREPALRKAIELA
                     LADAGAAPEDVDVVFADAAGVPELDRIEADAISAVFGVRGVPVTAPKTMTGRLYSGAAP
                     LDVATALLAIEEGLIPPTVHINPDEEYGLDLVLNQSRTAQVRTALVLARGYGGFNSAVV
                     VRAVD"
     aSDomain        complement(35010..36011)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35970_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.80E-32"
                     /label="IE289_RS35970_PKS_KS.1"
                     /locus_tag="IE289_RS35970"
                     /protein_end="402"
                     /protein_start="68"
                     /score="104.7"
                     /tool="antismash"
                     /translation="QTDHMTRMALVAAEWALADAGIDPKELPEYDMGVVTASSSGGFEF
                     GQGELEKLWSQGSQYVSAYQSFAWFYAVNSGQISIRNGLKGPSGVIVSDEAGGLDAVAH
                     GRRLIRKGTPMIVSGGVDASICPWGWVAQMAGDRLSTSDEPTRAYLPFDADAAGYVPGE
                     GGAILIMESAESACERGAKIYGEIAGYGSTFDPRPGSDREPALRKAIELALADAGAAPE
                     DVDVVFADAAGVPELDRIEADAISAVFGVRGVPVTAPKTMTGRLYSGAAPLDVATALLA
                     IEEGLIPPTVHINPDEEYGLDLVLNQSRTAQVRTALVLARGYGGFNSAVVVRA"
     CDS_motif       complement(35520..35558)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IE289_RS35970_0001"
                     /evalue="2.40E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="IE289_RS35970"
                     /protein_end="232"
                     /protein_start="219"
                     /score="14.1"
                     /tool="antismash"
                     /translation="FDADAAGYVPGEG"
     gene            complement(36212..37483)
                     /locus_tag="IE289_RS35975"
                     /old_locus_tag="GCM10010317_074220"
     CDS             complement(36212..37483)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (5-397). E-value:
                     3.3e-54. Score: 176.3. Matches aSDomain:
                     nrpspksdomains_IE289_RS35975_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     784.6; E-value: 4.6e-239)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385254.1"
                     /locus_tag="IE289_RS35975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074220"
                     /product="beta-ketoacyl synthase"
                     /protein_id="WP_054237210.1"
                     /sec_met_domain="t2ks (E-value: 1.5e-248, bitscore: 818.5,
                     seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.7e-55, bitscore:
                     180.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGRRVVITGIEVLAPGGVGAKNFWNLLSEGRTATRRITFFDPSP
                     FRSRVAAEIDFDPAEHGLRPQEIRRMDRAAQFAVVAARGAVADSGIDIDAYDPYRVGVT
                     IGSAVGATMGLDEEYNVVSDGGRLHLVDHAYTAPHLYNYLVPSSFAAEVAWAVGAQGPN
                     TVVSTGCTSGIDSVGHAVELLREGSADVMITGSSDAPISPITMACFDAIKATTPRDDVP
                     ERASRPFDGTRNGFVLGEGAAVFVLEELESAKRRGAHIYAEIAGYATRSNAYHMTGLRP
                     DGAEMAEAITVALDEARMNATEIDYINAHGSGTKQNDRHETEAFKRSLGDHAYRTPVSS
                     IKSMVGHSLGAIGSIEIAASALAMENHVVPPTANLTTPDPKCDLDYVPLVAREQLTDAV
                     LTVGSGFGGFQSAMVLARPERSVA"
     aSDomain        complement(36293..37468)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IE289_RS35975_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.30E-54"
                     /label="IE289_RS35975_PKS_KS.1"
                     /locus_tag="IE289_RS35975"
                     /protein_end="397"
                     /protein_start="5"
                     /score="176.3"
                     /tool="antismash"
                     /translation="VVITGIEVLAPGGVGAKNFWNLLSEGRTATRRITFFDPSPFRSRV
                     AAEIDFDPAEHGLRPQEIRRMDRAAQFAVVAARGAVADSGIDIDAYDPYRVGVTIGSAV
                     GATMGLDEEYNVVSDGGRLHLVDHAYTAPHLYNYLVPSSFAAEVAWAVGAQGPNTVVST
                     GCTSGIDSVGHAVELLREGSADVMITGSSDAPISPITMACFDAIKATTPRDDVPERASR
                     PFDGTRNGFVLGEGAAVFVLEELESAKRRGAHIYAEIAGYATRSNAYHMTGLRPDGAEM
                     AEAITVALDEARMNATEIDYINAHGSGTKQNDRHETEAFKRSLGDHAYRTPVSSIKSMV
                     GHSLGAIGSIEIAASALAMENHVVPPTANLTTPDPKCDLDYVPLVAREQLTD"
     gene            complement(37480..37809)
                     /locus_tag="IE289_RS35980"
                     /old_locus_tag="GCM10010317_074230"
     CDS             complement(37480..37809)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225: Polyketide synthesis cyclase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C17/C2-C19 (Score: 198.2; E-value: 2.8e-61)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383120.1"
                     /locus_tag="IE289_RS35980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GCM10010317_074230"
                     /product="TcmI family type II polyketide cyclase"
                     /protein_id="WP_054237209.1"
                     /transl_table=11
                     /translation="MYSTLIVARMDPGSSVDVAKIFGDFDDTEMPHRMGTRRRQLFQYR
                     GLYFHLQDFDADNGGELIQHARHDPRFIQISEDLKPFIEAYDPATWRSPADAMATRFYN
                     WEASA"
     misc_feature    complement(37853..37867)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.62"
                     /tool="antismash"
     misc_feature    complement(37856..37869)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.67"
                     /tool="antismash"
     misc_feature    37857..37871
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.35"
                     /tool="antismash"
     misc_feature    complement(37910..37924)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.41"
                     /tool="antismash"
     CDS             complement(37976..>38786)
                     /codon_start=3
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948354.1"
                     /locus_tag="IE289_RS35985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="biotin/lipoyl-containing protein"
                     /protein_id="WP_190172718.1"
                     /transl_table=11
                     /translation="YGDPALRGHSFEFRINGEDPGRGFLPAPGTVSTFAPPSGPGVRLD
                     AGVQCGSVIGPAWDSLLAKLIVTGATREQALQRAARALEEFEIGGMATALPFHRAVVKD
                     PAFAPELTGSTDPFTVHTRWIETEFVNDIPAFTNPAEAAEAEDEPGRESVVVEVGGKRL
                     EVSLPSSLGMSLARTGLAAGAKPKRRAARRSGPVASGDTLASPMQGTIVKVAVEEGQEV
                     KEGDLVVVLEAMKMEQPLNAHRSGIVKSLTAEVGASVASGAAMCEITS"
     gene            complement(37976..>38790)
                     /locus_tag="IE289_RS35985"
ORIGIN
        1 gggcatggaa gccgtcgagc aggacggagg tgtcggcgag gcggtgccag gcgctcacgg
       61 ggtcgtggtc ctgccggcgg tcgcccaccg ggtcctgcac acggtccgtg gggtcgcttg
      121 cggggtcctt catgcggtga agcctacgtg cgggtcctcg gccggctccg gggtgcgcgg
      181 cccctgagcg cgctggcccg ggagcttgcg ggcgccgggc ggaaacagtc gtccacgcgc
      241 gcgtgccgcc catccgccga ggcgccgcag gaacgacgtc ggcaggaaca ccgcgtcggc
      301 ggcgatcatc gcgagcgaga agaagggcag cccgaggacc acggcgatca cggcgtgctc
      361 ggtcatcatg gcggccagca ggacgttctt gacgcgccgg ttgatcaggg tgaaggggaa
      421 ggcgacctgc acggcgaccg tcccgtaggt caccagcatc acgatcgtgc cgtgtgaggc
      481 cagcaggtcg gacagggcgg gccaggggga gaagtagtcc aggtggagcg ggtagtagac
      541 ggccgtgccg tcctgccagc gcgagccctg gatcttgtac cagccggcgg tcgcgtagat
      601 cagacacgcc tcggccatga tcacgagcag ggccgcgttg tgcacggcgt tggcgatgac
      661 gtcgagcagg atccgaggct ccacggtgcg cgccaggcgg ccgacggccc accacagcgc
      721 ctggaccgcc cacagccccc agaagatcgc cagccagccg gggctgagcc gccccgcgcc
      781 cgtcgccgcg gccagcagca gaccgagcgc cgcccacagg acaagaccga cccggtcctt
      841 ggccccggcc tgtgggaggt ccccacgcgc gcgtgcctcc cgcgtgagcc gggcccgccg
      901 ggcgtccagc gaccacacct gtccacaccg cgtgaacacc agatagatcg ccatgaggtg
      961 gatgacgttg tcgccgccgt cccccatgaa gatgctgcgg ttctgcagcg agagcacgcc
     1021 gaccatgaag agcacggaca tcgtgcgggt ccgccagccc accagcagca ggagagcgga
     1081 gaggacggcc agggcgtaga cggtctcgaa ccacacctgg ctgtcggacc acatcaggat
     1141 cgtgaaggcg tggttgtccg cgacgagccg ctgggcgagg tcccacttcc acggtccgtc
     1201 ggggccgtac atctcctggc ggtgcgggaa ctcgcgcagc aggaacagca gccaggtggc
     1261 ggcgaagccg atgcggatca cggccgtctg gtacgggccg agggctgcgt cggtgacccg
     1321 ggcgatgccg cgcgagatcg acactgcgat gcggttcatc cggcgctcgc ctccgtccgc
     1381 gcgtccgtca cgtcctcctc gggaacggtc caccagggca gctcgcgcag gacgggcgtg
     1441 tcggacacct gctcctcgct ccatttcggg ggcggcacgt tggtggtacg ggaacggacc
     1501 tggacgcttt cgacgacggc gcccttgacg ccggccccct cacggtcgag acgcagcacg
     1561 acgatccggc gcagatagcg ctgggagagg tcgccgcgca ggcccaccgg gcggttgtcg
     1621 ttgtcgtgcg tgccgatgta gaagtcccag gcccggcgca gttcgttctg ctgggtgtgg
     1681 ctcggcagca gattgccgtc gatcgccgcg ccgtccagcg cggacaggtc gtaccagccg
     1741 gtctcggtga tgccaccgtc cgcgccgcgg acctgcgcac ggacctggac gtcgatgttc
     1801 tgctgcaacg ggttgggggc gaagagcttc cagttctgct cgaactccgg gtagatccag
     1861 tcgtcgatcg cccggccgtg ctgcttggtg accgtgttcg agggcgcgac gtgcaggaac
     1921 accatgccga ggtgcacaca ggcgacaacc gcgacgaccg cgagggcgag cgcggcgaca
     1981 acctgggagc ggagggggag ggaggctatg ccggtggggg tggggacggg gacgggggga
     2041 tcggcggcgg gtgcctgggg gccgagtgcc tgggggccgg gggcctgagc agtgggcgcc
     2101 tgggaatcgt ggtgctgcgg aacggattcc tggtcggtgg attcctggcc gacggattcc
     2161 tggccgacgg attcctggtc cgcggagggg gtgctgtccg gggtggaacc ggcggaggcg
     2221 gggccctcgg gcagggagcc gtcagggccg tccggcagat gccgggcctt cgagccctcg
     2281 tcgtacgcgt ccattccgcc ccgattcccg atcccggtcc gattcccgcc gccggaccgc
     2341 gcggcgccgt ggcgcccgcg cgcaccacac cgcggcgtgc gcacgggaac ggtactcagg
     2401 ccggaccgcc cagcacagcc ccattcggca cagcgggcac aacagcgaca caacagcgac
     2461 cccgaggtta tccacagcgg tggacaccct acggccgccc gccccgccgc gtggtgcgac
     2521 agaccgaccg ttcggtctgt ctggatggca ggccttccac ggctcgaccg ttcccttctt
     2581 gtagaacctg ttctatcttg acgctccgtc agatccggtg tccgccgggt cggtggatcg
     2641 gtgcgtggga ggacagggac gtggacttca ccttcaccga ggagcagcag gcggcggtcg
     2701 aggcggcgaa ggcggtgttc ggcggggtcg cgcccgacgg agtacccagc cccgcgatca
     2761 ccgcgggcgc cgtcgccgac gacttcgacc gggcactgtg gacgaagctc gccgacgcgg
     2821 atctgttgag tctgttgctc gccgcggagt acggcggggc tggcctggac gcgatcgcgc
     2881 tgtgcctggt gctgcgcgag gcggcgaagg tgctcgcgcg ggtgccgctg ctggagagca
     2941 gtgcggcggc ggtggccgta caggcgtacg gcggcgagga gttgaaggcg gagctgctcg
     3001 cgcgggcggg ccggggcgag gtcgtgctga ccgtcgcggc gaacgggcgg accgggcacg
     3061 acccggccga actcgccgtg accgcacggc gggacggtga cgcgtgggtg ctggacgggg
     3121 tgcagacggc ggttccgtgg gcggagaacg ccgacttcac cgtcgtaccc gcacacacgg
     3181 gcgccggccg gaccgtcctc gcgctggtac cccgggttca tgagggtgtc gtcctcggcg
     3241 agcagatctc cacgaccggg gaacggctcg gcgagctgcg tctggaatcc gcgcggatca
     3301 ccgcccggga ggtcatcgac gcggacgggg cgtgggagtg gctgcgggag ctgttggcca
     3361 ccgggacgtg cgcgctggcg ctcgggctcg gtgagcgggt gctcgcgatg accagcgcgt
     3421 acacgggcaa gcgggagcag ttcgggttcc cggtcgccac gttccaggcc gtcgccgtgc
     3481 aggccgccga ccgctatatc gacctgcggg cgatggaggc gacgctgtgg caggccgcgt
     3541 ggcggatcag tacgggggcg gggggtgccc ttccggcgtc cggggacgtg gccgtcgcca
     3601 agatctgggc atcggaaggg gtacgacggg tcgtgcagac cgcgcagcat ctgcacgggg
     3661 ggttcggcgc cgacgtcgac tacccgctgc accggtacca cgcctgggcc aagcagcttg
     3721 agctgtcgct cggaccggcg gcggcgcacg aggaggcact gggggatctg ctcgcggccc
     3781 atcccctggg ctgaacgccc acgcccgcga cacgcgctcg cctctccggg cgcgtcctcg
     3841 cttctccagg cctgggcaag ccccgggcag cggtggtgaa cgccgctcgg cggatgcgag
     3901 cgcgggcgcg aaccccctgc cggtggctgc agggggcgtg aaccctcgct gatcgctacg
     3961 gcacgaagct gggagtcccc ctggcggtgg ctacagcacg aagccggggg tgcccttgtc
     4021 gtccacgacc gggcggccgg cggcggccca gacctgcatg ccaccgtcga cgttcacggc
     4081 gtcgatgccc tgctggacca ggtacatcgt gacctgcgcc gaacggcccc cggagcggca
     4141 gatcacatgg accctgccgt cctgcggcgc cgcctcggtc agctcgccgt agcgagcgac
     4201 gaactcactg atggggatgt gcagcgcccc cgcggcatgg cccgcctgcc actcgtcgtc
     4261 ctcccggacg tccagcagga agtctccgtc cgcgagatcc ccgacctcga ccgtgggcac
     4321 accagatcca aaactcatgc ccccgacgct acccgaccgg gcaggcgacc cgaagccccc
     4381 gccggacagg ccctaggacc tgtccggccc tagccgacca gccgggccag ttccttctcg
     4441 cgctcgtcga cctgggccag cagctgctcg gcgatctcgt ccaggagccg gtccgggtcc
     4501 tccggggcca tcttgagcat ggcgccgatg gcgctctcct ccagctcgcg ggcgaccagc
     4561 gtcagcagtt ccttgcgctg ggtgagccac tcgaggcggg cgtagagctc ctcgctgcgg
     4621 ctcggcttcc actcctcggg caccgggccc gccgcccact cctcggacag ctcccgcagc
     4681 agggcctcgt cgccacggct gtacgcggcg ttgacccggg cgatgaactc gtcgcgccga
     4741 ctgcgctcgt cgtcgtcctg tgccaggtcg gggtgggcct tgcggaccag ctcacggtag
     4801 agctgacggg cctcgtcgct ggggcgtacg cgctgcgggg ggcgtacgga ctggtccgtc
     4861 agcatcgcca ccgcctcggg gaacagtccc tcggagtcca tccagccgtg gaagagctcc
     4921 tcgaccccgg gcatcggcat gacccgcgcc cgcgcctcgt ccgccttgcg tatgtcctcc
     4981 acgtctccgg tgcgcgcggc gaccgcctcg gcgatctgcg cgtccagctc gtcgagccgc
     5041 gagtacatcg ggccgagctt ctggtggtgc aggcgcgaga agttctcgac ctcgacgcga
     5101 aaggtctcca cggcgatctc gaactcgatc aacgcctgct cggccgcccg cacggcccgc
     5161 tccagccgct cctcgggccg cgcctgcggc tcgggggccg cctccggggc ggactcgtcg
     5221 tgggcatccg catccccggc gccctggggc cgggcatcct cggcctgggt acggtcggac
     5281 tcgctgtgct cggcttccgg ggtcgtcacc cgaccagact aggccacggc cccgtacgac
     5341 tcgcggcctt cccccggccg gggcggtgcg ccacgccccg gccccgccgc tctcggccag
     5401 acctcgctcc tctcagcccg gccccgctcc tctcgattcg gcggcgcggc ggtgtccctc
     5461 ttgcggctca ccgttgcggc tcaccgttgt ggctcacacc ccgagctccg ccgccaaccg
     5521 cccctccctg accgccgcga ccagctccgc gtggtccgcc tccgtacggt cggcgtaggc
     5581 cacggcgaac gaggcgatgg actcgtccaa ctcctcgctc ttcccgcagt acccggcgat
     5641 gaggcggggg tcggcggtgt gggtgtgggc gcgcgcgaga agggcgccgg tcatacgggc
     5701 gtagtcgtcg acctggtcgg cggcgagggc ggcggggtcg acgctgccct tgcggttgcg
     5761 gaactggcgt acctggaagg ggcggccctc gacggtggtc cagccgagca ggatgtcgct
     5821 gacgacctgc atgcgcttct ggccgaggac gacccggcgg ccctcgtgcg gcacctccgg
     5881 tatggcgtgg cctgccgtcg ccaggtgcgg gagcagcgcc gaggcgcggg cttccttcac
     5941 ctggaggacc aggggttcgc cgcggtggtc gaggagcagc acgacatagg agcgggtgcc
     6001 gacgctgccg gtgccgacga cgcggaaggc gacgtcgtgc accgcgtacc gggcgaggag
     6061 ggggaggcgg tcctcggaga cggtggtcag gtagtgctcc agcgaggccg cgaccgccgc
     6121 ggcctccgcg tcgggtaccc ggcgcagcac cggaggcgcg tccacgaagc ggtggctgcc
     6181 gtcctccgtc ggctgggtcg acttggccgc gaaccgtccg ctggtgttgg cccgcgcctt
     6241 ctccatgacc cgctccaggg tgccgagcag gtcgtgggcg tcggcgtggg agacgagttc
     6301 ctcgtccgcg atggcgttcc acgcgtccag caccgggagc ttcgcgagca gccgcagcgt
     6361 gcgtcggtag gcaccgaccg cgtcgtgggc ggccttgcga caggtgtcct cgtccgcgcc
     6421 cgcttccctg cccgcgagca cgagcgaggt ggcgaggcgc ttgaggtccc actcccaggg
     6481 gccgtgtgcc gtctcgtcga agtcgttcag atcgatgacc aggccgccgc gcgcgtctcc
     6541 gtacaggccg aagttggccg cgtgggcgtc gccgcagatc tgggcggcga tgccggtcgc
     6601 gggggtgcgc gcgaggtcgt aggccatgag gcccgccgaa ccgcgcagga aggcgaaggg
     6661 ggtggccgcc atcctgccga cccgtatcgg agtgagctcc gggatccggc cgaggttgga
     6721 ctcctcgacg gcggtcaccg cgtccggccg gccggcgtcg aagctcagct ccgcgtgcac
     6781 gccgcgcggc acccgtcggc gcagcgcctt gccctcttcc ttgggtgcgg cctgcacggg
     6841 ccggcccgcg aatccccgca cgccgaagac tccggagacc ctggacgcct gccgaccctg
     6901 ctcactccgg cggctttctt cgctccgccg gccctgttcg ccctgttcgc cctgttcgcc
     6961 ctgatggtcc tgatgtccct gatggccctg cccgcccggc cggctccgct ggtcctgctg
     7021 cgcccgatca gctgcaccaa gatccgtcat accgactgcc tcccccgtca cgcacgaaca
     7081 tcaactcggg atgaccgtac cgccggtggc cgaaacgcgt cagaccctgt ggacaactcc
     7141 cagcctgtgg aaaacccggc ccctgcgaat cagccccggt ccagggtcac ttgcggagtt
     7201 cgcccgggca cggcgggctc cccggcaggt gcttctccgc ccaggttccg agttccacga
     7261 gcgcgggctg cagtgcggcg cccgcctccg tcaggccgta cacgacccgc agcggaggac
     7321 cctcgtcgac ctcgcggacg accagccccg ccgcgccgag ttccgtgagg cggtcggaga
     7381 gcatccgttc gctgatgccg gggatcgctc tgcgcaggtc ggcgaagtgc gcggggtgcg
     7441 gcagcaacac ggccacgacc aggccggtcc agcgcttccc gagcagttgg aagacgcggg
     7501 ccatgccgtc gtcgaccctc tggcacggcc ctgcgtcgtg agtccccggc tctggcatgg
     7561 gtccagggta ctgtgttccc gtggggggat gaaaaaaagt aagtagctgt gttacctcta
     7621 gtccagtacg aaaagttcgc cctcttctcc tggagatccc catggccacc ctcctgcacg
     7681 tcgactcgtc cgttttcccg ggcgcagcct ccgcctcccg cacggtcacg gacgcgttcc
     7741 gcaaggcctg ggaggagcag cacccgcagg gcaccgtgat ctaccgcgac ctcgccgtga
     7801 acccggtccc gcacatcacg gccgacgccc acaccgccgg tttcgccccc gcggacgcgc
     7861 acacccccga gcaggccgcg gccttcgccg agcgcctgac gttcatagag gagctggagc
     7921 aggcggacgc gatcctgatc ggcgcgccca tgtacaactt cacgatcccc tcgaccctca
     7981 aggcgtggct ggaccaggtg atcctcatcg gccgtaccgc catgagcgag gactcgaaga
     8041 tcaagggcac cccggtcacg gtcgtcgcca gccgcggcgg ctcctacgcg ccgggcaccc
     8101 cgcgcgaggg ttacgagtac gtccagaact acctggaggc gatcctgcgc gacaccctcg
     8161 ccctggacgt ccacgtcatc gtcccggagc tcacgatggc gccgcacaac ccggcgatgg
     8221 ccgacctgat cccgatgtac gaggcctccc gcgccaaggc cgtcgacgag gcggtcacga
     8281 aggccaagga gttcgccgag cgcttcgccg cgtagcccct ccgggggagg gccgaatgaa
     8341 cccctgcccc ggtacgcccc cacgacgcga cggccccgca ggtgcgtgac ctgcggggcc
     8401 gtctgcatgg gccgccgaat gcccactgcc gcgggggatg gatcacagcg ggcatccggc
     8461 ggcggtaccg gggggacgag cgggccgagt gggccgagtc ggctacttga acgccgggag
     8521 gctgcggctc acccagccgg agaagggggt ggccgggcgg cccaggacct tctccacatc
     8581 ggggctgacc cgctgttcgg cggggagcgg ggcgccgagg atgtccaggg tgccggggat
     8641 gacgtcctcc ggcatgaact gggccaggtg ggtgtgggcg gcctcgcggg tcagttccac
     8701 gaaggtcact tcctcaccga tggccccggc gatcacctcg gcctgcgcac gcgggctgac
     8761 cgcttcgggg cctgtcacct cgtacgtacg accggcatga ccgtcctcac gcaggacgac
     8821 cgcggcgacc gcggcgatgt ccgcggggtc gacgactggc agggccacgt caccgaacgg
     8881 ggcgaagacc gtgcggtcgg cgcggaccga ctcggcccag gcgaaggcgt tggaggcgaa
     8941 tccgcccgcg cgcaggatgg tgaagtcaag gcccgagccg cgtacggcct cctcgaactc
     9001 gcgcagcctg ccgtgcgagg cggagtcggg gcgggtggcg ttgatctgcg aggagagcag
     9061 gacgacccgc ttgacgccgg cgtccccggc ggcggccagc aggtcggtcg cggcctcgcc
     9121 gtaaccgagc agttcgccgg cgagcaggat gaagaaggcg tcggcgcctt cgaggaccgg
     9181 ccgcatgctc tcggcgctgc cgaggtcggc ctgggcgtga cggacaccgt ccgtcgggga
     9241 gggcagcggg cggcgcgaga ccgccacgac ctgctccccc gcctcggcga gcgcctcgat
     9301 cagcggacgt ccgacatttc cggtggctcc agtgacgaca atcatcagaa aaaactccct
     9361 agtgcgttaa tccgaaccag taatcagcag tcatcggttg catcggtgtg gggattggag
     9421 tggagagggg ggtggggatc ggtgtgggga tcggtgtggg gaaatccgcc ggtcatccgt
     9481 ggtgggcggc catgacaggg acgctagcat cctccgtata gtaggtacct agaggaaagt
     9541 ggctatccaa gtgggtctct ttctcgcgcc cgccgtacac cgcggtgagc gaacggccca
     9601 gccgtacgag cgactcccgc gcctccggag gatcgagcac ctcgacgcgg ctgccgagac
     9661 cggccagttg cgcggcgagc acctccaccg aaggaccgtc ggccgtgaac tcgacccggc
     9721 cgtcgatctg ggcctcgccc gtccgcagcc gaccgcccag cagttgccgc agcaccggca
     9781 gggcgtcgcg gtcggcccgc gcccgtacgg tcgccgcggt cagccgctgt tccacctcgg
     9841 cggccaactc ccgccaggcg gcggcgaggt cgaaaccctc cgggcgccgc accggctcac
     9901 cggtcctggt cgcggaggtg acccggctga gccggaaggt gcgcagcccc tcctcggtac
     9961 cggcgacgag gtaccagcgg ccggccttcg agaccaggcc gagcgggtgc accgtgcgct
    10021 cacccggagc ccggtcggga tgggcgtagc cgagccggac ctgttcgccg tcgagcaccg
    10081 cccgctccag agtgtgctgg tgggggccgc caccacccgc cgtgcgcgac cagtcgacac
    10141 cgtcgatgag gatggccttg gcggccgcct cggcgtgcgg ccgcatgggc gcgggcaccg
    10201 cccgcatcaa cttccgtaac gcggcacgca gttcgggcga ggccgacagg gggcccgcgg
    10261 ccaggaacaa cgccccgatc tcccgcgagg tgaaaccggt cagatcggtg cgggcgccgc
    10321 cgaccaggct ccagccgcca ccccggccgc gctgcgagta gacggggaca cccgcggtgg
    10381 tgagggcctc caggtcgcgc cgcgcggtgc gctccgacac ctccagctcc tgggccacct
    10441 cgcgcacggt cacccgcccg cgcgcctgga gcagcagcag ggtcgccacc agacggtcag
    10501 ccttcacaac gaccggcccc ctccgagatg ttgagatctg agacgttgag atccgtgatt
    10561 ttgagaggct ttgagccaat acatctattt tcagcaagat ctgatgaggc ttcagaaata
    10621 ggccacaaga tgacctgttt gacctcgacg atgaagacat gactcaagac atggctgaca
    10681 gcaccaatcc ccccgccaac ccgcccaccg acccccgtgg cggcctgttc aaggccgtcg
    10741 agctcaccgg acgtacgctc gccgcgctgc gccccgagca gtacgacacc gtcaccccgt
    10801 gtcccgacta ctcggtccgt gacatggcca accacgtggt gtccgtgctg cgccgggtcg
    10861 ccgtcatggg cgcgggcggc tccttcatga gcgttccgca cttcgcccag gacgtccccg
    10921 acggcgactg ggccaaggcc tgggcggagg cgacgaagga gttcgacgcg gtgtggtcgg
    10981 acccggccgt actgggccgc cagatcggcc tgccctgggg cccggttccc ggggtggtcg
    11041 cctcggtgat ctacaccaac gagttcgtgc tgcacgcctg ggacctggcg aaggcgaccg
    11101 gccagagccc cgagtgggac ccggagatgc tcgccgcgcc gctggccaac atgcaccggg
    11161 ccgtgcccgc ggaaccccgc ggcggccagg tgccgttcgg tccggtggtg gaggtgcacg
    11221 aggacgctcc cgacatcgac aagctggtgg gctggtacgg acgtcgtccc tgacggggcg
    11281 acgcggcaga cgatcgagcg ggcgggccgc cggacatcga tccggcggcc tttccctctg
    11341 tccaggttca agaaatgtcc gggttcacga gatgtccggg ttcacgagat gtccgatttc
    11401 gtgagaggtc cgggatcacg aagcgtcagg ctccgatgcc ctgggcgaac ttgaagtagc
    11461 ggtacgggtc gtacttcgcc ttcacgacct tcagccgcgc gtagttctcg gcgtagtacg
    11521 actgccgcca gttcggcagc tccgcgtcca tccagttctg gtacgtctcg ccgttggaca
    11581 gcgggtcgat ggtgtcgaac ccgtggtcca cccagctcgt ggcgacggcc gtggcttcgg
    11641 cggtgacctg ggccgggtcg ttgatcagga cccggtagtt gacggagaag agcgagtcac
    11701 ggtgcacgta cgccgtgtcg gtgcgggccg ggtcgttggc cgcgcccccg aagaagtgga
    11761 agtcgaggta ccgggcctgc ccggccttgc ggtcggcgtc gaaggccgtc accacgttcg
    11821 cccagtcgct ctgcgcgtag ggcgcgctgc ccagccgggt ccgctccaga ccgaaggacg
    11881 gccgggtgag caccccgctc ggcgacttcc cggcgcgctg gcactggtcc tgggtcaggg
    11941 tgctgcaacc gaagatcatc atcatgacct gctggtacgt catgaccgcg tcctggcggg
    12001 ccgtcaccgc gccggtcagc gacagcagcc gcgccgcctc cgaggccagt tctgccgggg
    12061 tgccgcggga ggcgaggaag acgttgagcg ccggtacggt gccgggcgcc gcgtcggcct
    12121 ggacgaggta ggcgccgccg ccgatggtgc ggggggcgtc caccagccac tggcccacgc
    12181 cgtgcagcac gtcggccgcg cggtcgtacg ggaagatcag gttgctgatg gccatctggt
    12241 cgccctcgtg cggggtgacc gtgaagcggg tgacgacacc gaagttgccg ccaccgccgc
    12301 cgcggatcgc ccagaagagg tcggggtggc tggtcggcga ggcggtcacc acgcagccgt
    12361 cggcgaggac cacctcggcc gaggtgatcg cgtcgcaggc catgccggtc gggcgggtca
    12421 ggaagccgaa tccgccgccc tggaggaagc cgccggccga cacggtgggg cagccgccct
    12481 cgctgaccac cagggcgtgc ggggcgagcg cgttgagtat ctcgacgttc ttggcgccgg
    12541 ggccgatgtc gacggttccg ttgccgacgg tgatcgcgtt gagccgcgac acatcgatga
    12601 tcaggccggg cgtggtcgag tagccggcga agctgtggcc gccgctgcgg accgcggacg
    12661 ggagtccgtt gtcctgggcg aagcgcagcg cgacggagac gtcggaggag ctgacgcagt
    12721 acgcgacggc ccgcgggttg accgagtcga actggccgag ttccagctgc ttggccacgc
    12781 cgtagccgga gtcggtaggc agcaccagct gtccctggag cttgcctgcg agggtgctcc
    12841 agggggcgga ggagcccgcg gagacggggc tgttgggcag gacggccagg ccgacggcgg
    12901 cggttcccgc accgatcagt gctctacgag tgatcacgga tgtcccaagg ttctaggaag
    12961 cggtggatgt aggtggaagt cagtgggggg agacgtaaag gaaggagaag ggggccggcg
    13021 ccgggcccac ggggggaagg tgggcccggc gccggaaccg gggggaaagt ggctctgaga
    13081 agacgggccc gggagacggg ccttcgaggc ggtgccttcg agaggggccg aggtcaggac
    13141 accttgcggc cgcgcacccc ctgcttgacg acgccggcca gcatcgagcg gccgaggtcg
    13201 cgcatctcct tggggccgga ggtgctggcc caccacatga acttcatcat cgtgggggtg
    13261 gtggcccgga agaaccggag gtcctcggga cccttccagc cgaagggcgt gttgacggac
    13321 tcgcagtcgc ggatcgcctc gaagacgatg tccgcggcct tgtcaccgtc gatctcgccc
    13381 gcctcgtacc gctcgcaggt ctcggcggtg gtgtcgaaga ggaccttgaa ggcgtggctg
    13441 tccggccacc acagacccgt gtagggcgcc ttctccatct ccttgaagtg ccggtcgtca
    13501 ccgtcgagct ggaagttctg gcgcgccatg atctggcgca tggtggccgg cgtggtgaag
    13561 cacgcccaca cccggaacac cgcgttccac agccggaagt ggctgaaggc gatgtaggag
    13621 ctgttgacga tcttgtcgtt gtactccagg agcccctgct ccaggcgctc cacgtactcg
    13681 aagcgctcct cggtgaagtc gtcctcgcgc agggcgtcca ggatccggta ggcgagggcg
    13741 tcgacgacct cgaaggtgtt ggacagaccg cgcgagtaca gcgggtcgat gaaaccggcc
    13801 gcgtgcgaca tcaggcacca gcgggcgccg atggtgcgct tggaggagta ctggaggcgg
    13861 tcggtggaga cccactcgcg gatccgcttg gcgccttcga actgccgctt caccgccggg
    13921 tacatgtcga ggtagtggtt gaactcctgg tccggcgtca tgtccttcgg cttggggtac
    13981 agccgctcgt cgaaggtcag gccgacactg caggccgggt tcttggagtc cttgtagttg
    14041 tcgaacggga tgatccagaa ccagccccgc tcgatgaggt ggtgcagggt gccgccgtgg
    14101 aagggcgact cggcgggcgg gcgcagcgcc tccgggtagt tgcacacgtc gtcgtacggc
    14161 ttgatgccga cgtagtgcgt gaacagtgag cgcgcgtggt gcttgtgccg gggcgggttc
    14221 tcgcgcaggt cgaacttctg tgcgagcggg gagcggaaac cgctcgcgtc gatcaggtac
    14281 ttggcccgga agacctcgcc gttcctgccg gtgatggtga cgccgtcgtc gtcgacgtcg
    14341 aggtcggtgg cgaaccagtt ctggcggagc gtgcagccgt acttggcggc gacgttcagg
    14401 tagtgcgagt ccgtgtcctg gcggaagagg tgcaccgcct cggtgagcat cttcgggatg
    14461 acgaacatcg tcgcctcgtg cgggtccggc tcgcggttcg gccggtgcgt gacgaagccg
    14521 aagctctgct tgcggccgtg cgtcgggccg atgtgctcgg tgaccgcctt cacgtccagc
    14581 atgtgcttga tctctggcac gtcgtagcgc acggccagaa tgtgcagcca ctcgacgagc
    14641 tgcgggttct gggactcgcc gacggcgaac ctggggtgct gacctgcgtc gatgagcacc
    14701 acgttcgcgc cctgacgggc caggatcgct cccatgatcg agcccgcgag gcccgacccc
    14761 aggatggcta cgtcgcattc ggtccactcg gcggccttgt cggccttctt cgcttcctca
    14821 gccttggtgg gcaagaccgc actcctcttt ctcgtttcac ggacgggtcg gatgggtggc
    14881 gcgcgtccta ctggagggat tcggatcaac gggtcggatc aacgggtcgg gtcgaccggg
    14941 ggattcaggc ggcggtgccg ggctcgccga accactgggc gagcgcgtcg gtcaggccgt
    15001 ccgtggagcc gtcggcgccg acccaggcga tgtagccgtc ggggcgtacg aggaggtcgg
    15061 cggccggggc ggcggcgtcg ggccgggtgg cggtgacgac gtcgacgcgg tcggaccagg
    15121 cggccgcggc ctcgcgcagc gccgcgttgt cgtgcaggtc gaggaggacc gggcggccct
    15181 ggtgcagcag ctcgtacgtg gtggtcttct cgtcgccgac cagcagttcc tggtcgggca
    15241 gccggcggcc gagcagcggg tgaccgccct cgacggcgcc gtaggtgatg tccaggccgg
    15301 tgaccaggcc gacgaggtga cgtcgtacgt cctcgatctg gaccagttcg gcgaacaggt
    15361 cgcgcagcgg ctgggcctcg ggaccgccga ggtagagggt gcgctggacc agggtgttgt
    15421 agacgatgcg ggcgccgacc gggtggcgct cggagtggta ggtgtcgagc aggccctccg
    15481 gggcgtgccc cttgaccgcg gcggcgagct tccagccgag gttgaccacg tcgccgacgc
    15541 ccgcgctgat gccctgggcg ccgatcggca ggtggatgtg ggcggcgtcg cccgcgagga
    15601 agacccggcc cttgcggtac tcggcggcgt gccggctggc gtcggtgaag tagctggtcc
    15661 acagctgctt ggcaccgctg atgtcctcgc cggtcacccg ctggaaggcg gcggccacct
    15721 cctcgaaggt gggcggctcc tgggtggggc ggacaccggc gccgcgctcg aagaccacca
    15781 cgcgggtggc gcccgggccg agcggcagga ccacgaccat gccggcctcg ccgacctcac
    15841 cggtggggcg cagccgcagc tggactccgg cgacgtccgc catcttcatc tcgatggtgg
    15901 cgctgacgcc ggggaagtcg atcccggcca ggtggcggac ggtggagcgg gcgccgtcac
    15961 agccgacgac gtacgcggcg cgcagcgtct cgacgccctc cgggcccgcg acctcgacct
    16021 ggaccccgtt ctcgtcctgc gtcaggccga tgacctcgtg gccccggcgg acgtcggcgc
    16081 ccagacccac ggcccacttg ttgatgatgg cctcggtgcg cgactgcgga acaccgcgga
    16141 caccgaaatt gccgccctcg acaatgcggt agtcgatggg gagtccaccg aaatggccgc
    16201 cgggtatggt ctccagcgga ccgaaatcct cgagaaggcc gcgctggccg aattcctcga
    16261 tcgtacgggc ggagaatccc agcgcacggg actgctgcat cggctgttcc agccggtcga
    16321 gcacgatgac cgagagacct gagaggcgca gttctcccgc gagcatgaga cccgagggtc
    16381 ccgctccggc aacgatcaca tcggcattga aggcgtccat attccctctc ccgctggcgt
    16441 tttctccagt attccgaggg ctcccgggaa gctgaatggc cgccgataca ggactctgac
    16501 aagttcgtca gaggccttgc agctactggg cggtacgggt tggcgagtac tgggcaggta
    16561 caggcggagc atgcgagagg gtgccggaag cgtcttccgg caccctctcg ccccgtatgt
    16621 gctccgggag ttcggtacag gccgttcagt acaggcccat cacgcggtcg accgcgatct
    16681 cgatgaccgc gaggcccggg ggctgcggcg gctgggacca gtaccgcttg gcgtagcgcc
    16741 gcatcccctc caccacccgg ggcgggtcgg tggagacggt ggccgggccc tccagggtga
    16801 tccagcgggg gccgaccagc tggcacacgg cggcccggcc accggccctg gctaacaggt
    16861 tgcgggactt gcggcggtgc accgtggtca tcacccgggc caggcccgcc tcgccgtccc
    16921 aggtgaaccg tacgggcgcg acgtgcggcg tgccgtccgg gcgaagggtg gtgagggtgc
    16981 acagggcgtt ctcggcgagg aactcctccg ccgcggcgga caggggcagg ggttgggaca
    17041 tggccgggtc cgttcttccg tcgtccgact tcggtctctg gtctgccgtc aggcgtgcgc
    17101 ggggacggcc gcggactgct cggaggacct agtgaaaggc agcagcacca aggtcaccac
    17161 gaaggcggcc gcggcgaagc aggcgcccac gaggaacgcg tcgtggaaga cggtcgtacg
    17221 ggcctcctgg accagggcgg gaacaccgtg ggccttggcc gtcagctcgt cgacccggcg
    17281 gaaggcgtag gtcgccgcga ccgcgaggcc gagcgcgccg ccgacttcct gggcggtgtt
    17341 gatgagaccg gcggccagac ccgactcgcg ctcctcgatc cccgcgaacg cggagacctg
    17401 cagcgggacg aaggacattc cgaggccgag gcccatcagg acgaaggcgg gcagcacgtc
    17461 cgtcaggtag gaggcgtcgg acggggcacg ccacagcagc atcatgccgg tcgcggcgag
    17521 cgcgaggccg accagcagga cgggcttggc ggcgaccttg gtgacgacct gggaggcgac
    17581 gccggcgccg acggcggtga gcaccgcgag cggcacgtac gcgaagccgg tcttgacggc
    17641 ggagtagtcc aggacctgct gcatgaagag gctggcgaag aagaacaggg tgacgcaggt
    17701 gccgagcagc aggatggcga tgccgttggc ggcgcgcagc gaggggcggc ggaagatgcc
    17761 gagcggcatc agcggctcct tggcgcggcg ctcgatgacg atgaaggaga cgagcaggat
    17821 cgcggagagg atgaacccgc cgacgacccg gccggtcggg acattggagt cggagacggt
    17881 ctgaccgagg gtgaagatca gcaggaccag gccggcggtg agggtgaccg caccggcgac
    17941 gtcgaaggac ttgctgcgct gggcggagcg gctctcgccg acgaccatcg gggcgaccag
    18001 ggcgccgatg acgccgatcg ggacgttgat gaagaagatc cagcgccagc cgggcccatc
    18061 ggtgagcaga ccgccgaggg tgacaccggc gacggcggcg agaccactga gcgcgcccca
    18121 ggcaccgagc gccttgttgc gggccgcgcc ctcttcgaag ttgttggtca gcaggctcag
    18181 cgcggcggtg gcgatgaacg cggcccccag tccctgggca ccgcgggcgc cgatcagcat
    18241 cgcggcgttc tgcgagaccc cggcgagcag cgaggaaccg gcgaacagga gcagaccggt
    18301 ctgcagcatc cggcggcggc cgagggtgtc ggcgagccgg ccggtcagca gcaggaagcc
    18361 gccgaggagc atgccgtagg tggtgacgac gtactggaga gcggtggtgg agatgttgag
    18421 ctcgtcctcg atggtcggca gggcgacgtt cacgatcgac acgtcgagga aggtcatgaa
    18481 gccggccagg cagaggaagg ccaggatgag gccggggcgg cggaccggcc cggactcgcc
    18541 cgccgcctgg gcggggctgt gggtggactc ttggatggac atgtcactcc ctaggagcat
    18601 gaggattctc ggacggggac gtacagggag gtactggctt tgctggcttc ttggaagcta
    18661 gcatcctggg tatagtaggt acctagagga aagtgacttc ccgaaaggtg atggtcggaa
    18721 tgaagagcac agtcacgcag ggccccacgg ccgcgagcgg cgccgccgac gcgaccggca
    18781 tgccggtcat gaccagcccc gaagccgcgc acgcggccgc cgccggcacc ccgcagaggt
    18841 gtccgatcgc cccggtcctc gacatcgtgt tcagccgctg gaccacgccg atcctgtgga
    18901 cgctgaacgc cttcggcacc cagcgcttcg tggaactgca ccgcaacatc ggcaccatca
    18961 cgccgaaggt gctgacgcag cggctgcgtc agctggagcg ggacgggctg gtgatccgca
    19021 cgtactaccc ggaggtgccg ccccgggtcg agtacgagat cagcgatctg ggacggaccc
    19081 tggcccccct gttcgcctcg ctcttcgact ggtcgaccgg ccacctgccg ctggtggagc
    19141 aggcgcggca ggcgttcgac gaggcggagg agcaggccgc ggcccgcaac cactgagccg
    19201 ggtaggtccc tcagctccat gccggtgtcc gcatggagcc ctggaagaag atcagcgggt
    19261 cctcctgttc ggcctcggag ggcgcgcgca gaccgacgac ctcgcccagc aggatggtgt
    19321 ggtcgccgcc gtcgtactcg gtgaccagcc ggcactccag atgcgcgagc gcctcgctga
    19381 gcaccggcag gtcgaggacg gacctgtggt gcggcacctc ctcgatccgg gcggtccgcc
    19441 gaccggcgaa cgcccaggcc acgggctcct gtcgctgcgt caggaagttc acgacgaagc
    19501 cgccggactc ctggaccacg ggcagcagcc gggagttgtc gtgcaggcag atgagcacca
    19561 gcgccgggtc cagggagacc gaggtgaagg agttcaccgt ggcgcccgtg gcgttgtcgc
    19621 cgctgcccga ggtgatgacc gtgacaccgg tggcgaagtg tccgcacacg gtgcgcagcg
    19681 cgcggccgtc gaccggaccg agctgctcgg ggatggcttg cgaaacgggg atcacgacag
    19741 ccctctcgtt ctcggatacg gggttacgga gttacgcggt tacggagtta cgggggttac
    19801 cgggttcggg ggttacggag tccggggtta cggagtccgg ggttacggag tcggggggtt
    19861 cggagtccgg gcacgcggag ttacgggggt tccggggcgt tcctgatcag gcggcgcgtg
    19921 aagccggggc ctcggacggc tcggacggct cgggcacgac ggccggcacc ggacgacgcc
    19981 tggacagcag cggacccgcc atcgccgtcg tgaccagcgc catgatcacg agcatcgtga
    20041 acatgcgggt gtcgagcacg cccaggctga cggccgcgtt gaggatgatg agttcggtca
    20101 gaccccgggt gttcatcagc agccccaggt ccttcgactc acgccaggag aacccggcca
    20161 gccgtgccgg aagaatggcg ccgaccagct tgccggtgca ggccacgacg atgatcgcga
    20221 cgagcgcgac gaagtcaccg gcggtgagcg caccgaggtc cacgccgagc ccggtgacga
    20281 tgaagaagac cggaagcagc acgacgctga cgtggtccat gggcttgcgc agatgctccg
    20341 cgaggaccat ggcgggctca cggggcatca cgaacccgaa caggaaggcc ccgaagatgg
    20401 cgtggatgcc gatccaggtg gtcagccagg ccgaggtcag ggcgcccgcg cacagcaccg
    20461 cgagcagcgc cgaccagcgc tcggtggccg cccagcgcca caccagccgg gccaccagcg
    20521 ggcgtacgac cagcagcatc ccggccacgt agagcacgct gtagagaccg atgcgggcga
    20581 ggtcggagta gttcccgttc gccgtgacca gggccgagac ataggccagc aggcaccagg
    20641 cgagcaggtc gtcgatggcg gcgctggcca gcgagagcga accggcccgg gtgtccagga
    20701 gcttgttctc ggtgaggatc cgcgcgagca cggggaaggc ggtcaccgac atcgcggtgc
    20761 cgatgaaggt ggcgaacgcg acgaaggaga tgtggtgtcc ggccaccgtg gagtgctcgt
    20821 cgtacaggaa cggggccagc gccacaccca ggccgaaggc catcgcgatc gacgagagcg
    20881 agacgcccgc ggcgagccgg gcgtgcggcc tgatcaggcg cttctcgaac tcccagccca
    20941 ccacgaacat gaacaggatc agaccgacct gggagaccgc ggacagcaac ggccgcacgt
    21001 cggcggggaa aaggtgctcg gtgaggttcc ccggcagcag accgaggacg ctcgggccga
    21061 gcaggacgcc cgcggtgatc tcgccgacca ccatcggctg acgcagcttc tgcgcgagcc
    21121 ggccgagtgc ggcgccggcc acgagcacca cgccgatgtc ggcaagcatg atcgcgagtt
    21181 tcatgtcctg gggactggcc gccgccagcg tcgtcattgg ggctcccggg gtcggggcgg
    21241 ggtgccgcgg gtccacagca cgcggaaggt cagggaggag agccgccagc cctcggcggc
    21301 gcggcgggct tcaccggtcg cgagggtgcc gacctggaac aggggctcgt ccgccgcgtc
    21361 ggggtggtgc acatgcgtcg agacgaggtt ggcgcgcagc acggcccgct caccggcgtc
    21421 gtcgaggtcg acgaccgcgg gcgaaccgag gtgctgggtg gcggcgaagg ccgccagcgc
    21481 gtcacggtgg tagccggcga gtccgtcgag gccctcgtgc cggctcatgg ggaactcgac
    21541 cagggcgtcc ttcgtgaaga gcccccgcgc ccacgcgtcg tcgagttcgt cgtcgtcgag
    21601 accgatgagg taccggtcaa ggagagtgga tatctctaat gcttccgggc ctgactgcat
    21661 tacccgagca tggcgcccac gccaatcggc aaccaaggcc gcttttcaca gccctgacga
    21721 agttgagaaa gatctgacac cgccctcgaa caattgacaa aagcgccgcc aatcctgaag
    21781 tgccgaccct ttcacatggg cagatcttct tgccatgctg cattcgtagc tgcattcgtg
    21841 gctccacccg caccttcatt cgcacctcca ttcgcactcc catttcctcg aacggaagag
    21901 acgagagaat gccgaagatc gcagccgatg gtcagcacct gaccgttctc aacctgttct
    21961 cgaccgacgc cgccgagaag caggtcaagc tgctcgccgc gatgcgccag atcgtcgaca
    22021 cggcggccta cgagggctgg atatccagca cggtccacgc cgggcaggac aagccgggaa
    22081 cggccaactt catccagtgg cgcagcaccg aggacctgga gagccgttac gccggtgagg
    22141 agttcaagca ccgcaccctc ccgctcttcg gtgagatcac cacctcgatc cgtctgctcc
    22201 agaacgagat cgccttcacg cagcagaagc cggagctggg cggcgtcacc gagatctccc
    22261 cgtcccgcga cgactacacg gccatcgagc tgttcggcgt gctgccggag aaccaggagg
    22321 acctgatcga cgccctgggc gagtcccaga cgtggctggt cgacgtcccc ggctaccgca
    22381 cccacacggt gctgcgcggc ctgcgtgccc gcggcatcga gggcaagttc gtcgtcgtct
    22441 actcccagtg ggacagcaag gaggcgtacg acgccttccg ctccgcgccg cagggtgagc
    22501 gctccccgga gcgccagaag gtcgacgccc gcgtcgccgc gctccagacc tggcaggacg
    22561 agaacaccta ccaggtcgtc cacacccgct ccgcgggcga gtgagccacc cggtggcggg
    22621 ccgaccggtc gggcggcggc cggcccgcca ccgggtctgc acgttgtttc acgtgaaaca
    22681 cccgcacggc ggctctgaag acatggcagc cccgcccgca cggcagaacc atccgcagca
    22741 ggtgcacgca caacagaagc acgtatgaca gatcgcgcac ggacgcggac gcacgggcgc
    22801 gttcccatcc ccactggctg gccgctgccg ggaatccccc acccggcagc ggcttttctg
    22861 tccgtcacgt tcccgttccc gtcccgcccc cgcgcgccac accaggacga ggagacagca
    22921 cgcatggaac acccgggcat gcgccaagtc gcgcacgaga tcaacatcgc ggtcccggcg
    22981 gacaccgtcc accggctgat cgccgaggtg gggaactggc cacggatctt cccctcggtc
    23041 atccacgtcg agtacgagga ggctcccgag ggcgaggagc ggctgacgat ctgggagacc
    23101 gcaccgaccg cggcgggcga accgcgctgc cgtccgctgc gccggatcgt cgaacccgcc
    23161 aagctgcggg tcaacttcca gcacctggtc accgcgtccc ccgtcgccgg cctcggcggc
    23221 gcctggctcg tcgaaccgct cggggagaac gcgtcccgag tacggctgct gcacgagttc
    23281 cggaccgccg acgacgaccc cggggccctg gaccggatcg gcgccgagat cgaccggagc
    23341 gccgtcacgg aactcgcggc actgaaggag aacgcggaac gcgaatacgc cgacgccgag
    23401 ttgacgttct ctttcgagga caccgtccat gtcgacggct ccgccaagga cctgttcgcc
    23461 ttcatcaacg aggcgaacct gtggtcggag cgtctgccgc acgtcgccac ggtccgtctg
    23521 gaagaggaca ccgtggggct ccagaccctg gagatggaca cccgggccaa ggacggctcc
    23581 gtccacacca ccaagtccta ccgggtgacc ttcccccacc agcacatcgc ctacaagcag
    23641 gtcaccctgc ccgcgctgat gaccctgcac acgggccact ggacgttcac cgacaccgac
    23701 cagggcgtcg cggccacctc ccagcacacc gtcagtctca acacggacaa catcgcccgc
    23761 atcctcggtg acaccgccac cgtcgccgac gcccgcgagt acgtccacac cgccctgtcc
    23821 accaacagcc tggcgaccct gaaccacgcc aaggctcacg cggagggccg ccgttgaccc
    23881 cgacggtgcg ccggctcgcc gtagcgcgag gggagttgga cgtgtggctg ctgccaccgc
    23941 ccgactcgcc gcgtgacgtc ccgtacgacg agctcgacgc gtacgagaga ggtcgggccg
    24001 actcctaccg tcgccccgac gaccgccaga tgtacgccgc ggcgcacgtg ggactgcgcc
    24061 gggtcctcgc cggttacacc ggcatcgaac cgagccggct caatctcgcc ggcgagcggt
    24121 acaacggcaa cggtgaacgc cacggccgac ccgtggtgct cggcgtgccc ggcggcgccc
    24181 cccagttctc gctctcgcac agccacggcc tggcgatcgt ggtggtggcg gagtcccggg
    24241 tgggcgccga cgtccagcga ctgccgtcgc cccagaccgc cgaggcgtgt ctgccggcgc
    24301 tgcatccggc cgaacgtgag gagctcgaga agattcccga gcacgaacgg accatggctt
    24361 tcggccgcct gtggacacgg aaggaggcct atctgaaggg gttgggcacc gggctgaccc
    24421 ggggggccga cctcgactac cttggtgagg cggggctggc cgagcggccg acggggtggg
    24481 tggtgggcaa cctgcccctg tgttccaccc acatcgcggc ggtggcgctg gccggggcgg
    24541 gggatcggcc cgtcgctctt cgcgccgtgc ctaccgctta tctctacgcc ccggacgcgg
    24601 tggagcgtct tgtggagatg gaaccggggc tacggtcgat gctccgggat cctgctcagc
    24661 atggggatct ggagcgctga ggagatgggg ggactgcggg tcgggctcag gatgcgggtt
    24721 gtcctgggct ggtcgcgcag ttccccgcgc ccctgagggg gcacgaccaa ggggccggag
    24781 agttctggtg aactctccgg ccccttcggg ctgtggtgcc cgtggcgggt tcaggctgcc
    24841 gctcgccagg tgcgggggcc gtcgaagccg gtgacgcgtt cggggcggcg ccacagggcg
    24901 acgacctggt gcttgcgggc cgtgtcgtcg ggtgcgacgc cggggcccgc ggtgacggcc
    24961 atcagtaccg cggtcagcgc ggccagctcc tccggggagg ggcagccgcg ctcgatccgg
    25021 aaaagcggac cggccgcggg ttcggagacg ggatcggggg cgggatcggg aacggggaca
    25081 agggcggggc gctggatact catggtttcc tccctgctca ctggggcggg ttgccgtgct
    25141 tgcggcgcgg cagctcggcg tgcttggccg cgagcatggc gagcgaacgg gccaggaccg
    25201 cccgcgtctc gcgcgggtcg atgacgtcgt cgaccagccc gcgttcggcg gcgtagtaag
    25261 ggtggaccag ctcctccttg tactggtcga ttttctcttg acgcatcgcg tcggggtcgt
    25321 ccgcggccgc gatctcccgc cggaagacca cgttggcggc cccctcggcg cccatgaccg
    25381 cgatctcgtt ggtcggccag gccagcgcga tgtcggcgcc gatggagcgg gagtccatca
    25441 cgatgtacgc gccgccgtac gccttgcgca gcaccaccga gacccgcggc acggtcgcgt
    25501 tgcagtacgc gtacagcagc ttggcgccgc gccggatgat gccctcgtgc tcctggtcca
    25561 cgcccggcag gaagccgggc acgtcgacca gcgtgaccag cgggatgttg aaggagtcgc
    25621 agaactgcac gaaccgcgcg gccttctcgc tcgccttgat gtccaggaca cccgccatgg
    25681 cggccggctg gttggcgacg atgccgacgg tgtgaccgtc gatccgggcc agggcgcaga
    25741 cgatgttcgg cgcccagccc gcgtgcacct ccacgtagtc gccgtcgtcg acgagttcct
    25801 cgacgacccc gcgcatgtcg tacgagcggt tgccgtcgtg cggcaccagg tcgagcagca
    25861 cgtccccgga ccggtcgccc gggtcgccgc tgacgtgccg gggcggcagc tcgcggttgt
    25921 tggacggcag cagcgacagc agatagcgca cctcggcgag gcagctctcc tcgtcgtcgt
    25981 ggacgaagtg cgccactccg gagacagcgc cgtgcacatc ggcgccgccg agcccgttct
    26041 ggctgatctc ctcgccggtg accgcgcgga ccacgtcggg cccggtgatg aacatctgcg
    26101 agatgtcccg gacggcgaag atgaagtcgg tcagggcggg cgagtacgcc gcaccgcccg
    26161 cgcacgggcc gagcatcacg ctgatctgcg ggatgacgcc ggaggcccgg gtgttgcgct
    26221 ggaagatgcc gccgtacccg gcgagcgcgg agacaccctc ctggatacgg gcgcccgcac
    26281 cgtcgttgag cgacaccagc ggcgccccgg ccgcgatggc catgtccatg attttgtgga
    26341 tcttgcaggc gtgggcctcg cccagcgcgc cgccgaagac acggaagtca tgggcgtaga
    26401 cgaagaccgt acggccctcg accgtgcccc agccggtgat cacaccgtcg ccgtagggct
    26461 tcttcgcctc caggccgaag ccggtcgccc ggtgccggcg cagcggttcg acctcctgga
    26521 agctgccctt gtccagcagt agctcgatgc gctcgtgagc ggtcagcttg cccttggcgt
    26581 gctgtcgttc ggtcgccttc gggtcctgtc cggcacgggc gatgtccttg cgttcggcca
    26641 gctccatcag ccggccgccc agttcgatgg gtatcgcggg ctccatgtac ggatctccca
    26701 ttcaagtgga tcaagaggaa agacggttcg gtcagcgggc gagcaacgcg gtcagttcgc
    26761 cgacggtgct ctcccgcagc acctcggcgg gcacctcggc gtcgagggcg cgccggatcc
    26821 ggcgccccag gtgcagggcg tcgagcgtgt ccaggccctg gccgcgcaac ggcagaccgg
    26881 gcgagagccg gtgccccggc gggaccgcga gcaggtcatg cagttcgagg cgcaggcagt
    26941 ggccgatggt gcgggcacgt gcgtcggggg ccatggcgcg cagctggacc gggtccggga
    27001 gccggtcgag ccaactgcac ggggtgtcgt cactcagggg actcatgggg ctgcctttca
    27061 gggagagggc cgggcccgag gagtgccggt tccggccggt ggctggggag gaatcggcgt
    27121 gtacgccccg cgagcagcac cgcgagcgcc gccgccgacg aggcgagccc tcccacgtac
    27181 aggccggagc gcgcaccgtg acgaacggtg agccagccca cgaggagggc gccgagtggg
    27241 gtgagtcctt gcaggatgag cgtgtagagc gccatcaccc ggccgcggta ggcggcgtcg
    27301 ctgcccaact ggatgcggtg gttggcggcc tgggcgaagt agagggtggc gaagccggtc
    27361 agaaacagca gcacggccgc ccacgcgtag gtgggcgacc agcccgccgc cgtctcgagg
    27421 agcccgaagg cgagtgcgga ggcggtgacg gtcagggcgg ccgggcgggc gctgcgcacg
    27481 gtggtggcga acgcggcgag cagcgaaccg gcggcgaacg ccgtggtcag cagcccgaac
    27541 gcggtcgcgc ccgagtggaa gacggtcttg gcgagcagcg gcagggtgag ttggaagttg
    27601 aagccgaaca ggccgaccac ggcgaccagt gccagcggca cgaacaggtc ggggtgcccg
    27661 cgcacgtacc gcagcccgtc gaccaccttg accccgcgct ccggcggggc cgtgcgcagg
    27721 agttcccccg ggcgcatcag ccgcagcccg gtcacggtgg cgagatagct ggccgcgttg
    27781 agcagcatgg ccgtccccgc gccgaccgcg ctgatcagca gtccggcgag ggcggggccc
    27841 accacgcggg cggtgttgaa gtaggcggcg ctgagcgccg aggcgttggg cagcaactcg
    27901 gggccgacca tctcgctgac gaacgccatc cgggtgggca cctcgaccgc gttgacggtg
    27961 ccgaggccca gcgcgaacag atacagctgc cacagctggg cggagccggc caggacgagt
    28021 acggcgagtg ccagcgcgag ggcgccggag accaggttgg cgacggtgag cagcagccgc
    28081 ttgtcgtggc ggtcggcgag ccggccgccg tacagcgtga acagcagcag gggggtgaac
    28141 tggagcgcgg tcacggtgcc cagggccgtg ccggagtccc ccgtcaggga gagcaccagc
    28201 cagtcctggg cggtgaccat catccaggtg cccgcgaccg agacgacctg gccggccgcg
    28261 aagagccgga agttgcgcac ggccagggac cggaagggcg tacgacggct gccgacgccc
    28321 ccgggccgcc tgcccctcct tccccgcctc gccctcttcg tcgtgtccct ggcgtcgggc
    28381 cgtgtggtcg tcatggcatc agggcgtcac ggacgcgccc gcggaccggc gtgcgaggca
    28441 ttcctcgaag aacgcgaacg cgcgcaggtg gtaggtgcgg gcggcccagc cgaggctgat
    28501 gttgtgcccg gcaccgggct gacggtcgac ggcggcggac ggcgccgagg cgaagtgcgc
    28561 ggcgaggtcg gcgacggtgt cctcgtcgtg gtgccaccac agttcctgct cggcgaacgt
    28621 cagccgcacc gggacctgca cggccgccgc cgcgaccggg aaccgccgcg gccactggag
    28681 tgcctcggcc tgctcgcgcg ggggcatcgg ggcgaccagc ccctccgcct cgcggaaggt
    28741 gttcggcggg tagaagcgca gggcacccca gttccgcttc cagtgccggt gctggtgcgg
    28801 gtcggggccg ccctccgggt ggtcgaccgc gtagtcccgg ccgagcccgg agatgtcgag
    28861 cccgagcagc ggcggtacgg ccggatccgg atcgccggcc tggcaggcgg cgtacgtcag
    28921 ggcgagcttg ccgccgaagg agtgcgcgag caggaacacc ccggcgcccg tctcggcgcg
    28981 gccggccagg tgccgcagcg ccgcgtgcag cgctgcggac tgctcggcca gggtctgacc
    29041 gctcggggcg tccgcggcgg acagcccgta gccgggccgg tcgacggcga ccatggtgta
    29101 gccgagccgg gcgccgaggg cgagcaggga gacgtcgggg tgggcctgcc cgtcgaagta
    29161 cccggcgctc attcctcccc cgtgcaccgc gacgaccgtg gcccgcggtg gcccggacgg
    29221 ttgggcgatc agcgcggaga gcgtgacgtc accggccgcc agggcgacgg ggcgcacacc
    29281 cggggacatc gagggcatgg ccgaaccggg tacggacgag gggatggtct cgaccgtggg
    29341 aacgctcact ggggtacttc ctctcgtgtt cgtgcttgcg tgttcgtgct tgcgtgtggg
    29401 tgctctcgtg cgggtgctct cgtcttggtg ctcgcgtgcg gatcggttgc cggtggtggt
    29461 tctcagcggg cctcgggtgc gccgaaccag cggtgcagcg tcgcgcacag ctccgccgaa
    29521 ccggtgtccg cccaggccac atagccgtcg gggcggacca gcaccgcggc ggcgccgccg
    29581 aacgcggccg ggtcctgcgg ggtgccggtg acgacggtga cgcggtcctt ccagcgggca
    29641 gccgcctcgc gcagcacgga gtcgtcggcg aggtcgagca gcacgccctg ggcggcgtgg
    29701 aggagttcgg gcgtacggac ctcgccggtg gcggtgttca gcgcccgcgg cggcaaccgg
    29761 cgcccgacca gcgagtcccc ggtgtccccg aggtcgtagc ggacgtcgag gtggctgacc
    29821 accccggcga ggtgccgctt gaccgaatcg aggccgatga gctcggcgaa cagatcccgc
    29881 agcggctggg actcggggcc gccgaggaag accgtgccct gtgccttggt gttcatcagc
    29941 agccgcgcgc cgaccgcgtg acgctcgtcg tggtaggtgt cgagcagtcc ttcgggggcc
    30001 cggccctgga cggtcgccgc cagcttccag ccgaggttga ccgcgtcctg gacaccggtg
    30061 ctcagtccct ggccgccggc cggcaggtgg atgtgcgcgg cgtcgccgac gagcagcacc
    30121 cgcccgcgcc ggtactcggt gacctggcgg gtggcatccg tgaaggagct gacccagtcc
    30181 gcgccgccgc cggagatgtc ctcacccgtc aaccgctccc aggccgcggc cacttcggcg
    30241 aactccgggg tctcactgcg gtcggccggc ggggtgccgt gctcgcacac gatgatccgg
    30301 tccacgccct ccttcagcgg cgcggccatc accatgccgc cgggcagccg ctcgcccagg
    30361 aagcgcggcg ggatctcgca gccgacgaca tccgcgaggt acatgccgcg ggtggcgggc
    30421 gtaccgggga agtcgaagcc cgcggccttg cgcaccgggc tgtgcccgcc gtcggcgccc
    30481 accaggtacg cggcgcgcag cgtgcgctcg ccgtcgggcg cggccacggt gacggtgacc
    30541 ccggtcccgt cctgctccag cgccaggaac tcccagcccc gccggatgtc ggcgccgagc
    30601 tcacccgccc actcctccag aaccgcctcc gtctgggact gcgggacgcc gcgggccccg
    30661 aagtgggcgt cctccagcac ggtgtagtcg aactgcaccc ctccgaagtg acccatcggg
    30721 ctcttctcca gcccgccgaa gcgcgggaca agaccgcgct ggtcgaagga ctccatggcg
    30781 cgggcggtga acccgagccc gcgcgactgt ccggtgggcc gcgccagccg ctcggcgacg
    30841 atgacactca ccccgcccag ccgcagttcc ccggccagca tcagcccggc cgggccggcg
    30901 ccgacgacga tgacgtccgc gtccatctgc gcgtccatgg gtgtcctctc ctcgcgcgcc
    30961 cgggcgcgcg tcgcatcggt gggtgacgtg cggtgcctca gctgtgcgtg tgcttgtccg
    31021 tgcgtgtgcg tgcgtgcgtg tgcgtgagct tgtccgtgcc ctgccgtgcc gtgcctttgc
    31081 ctgtgcgtgt gcttgtccgt gacgggcccg tgcggtcgta ctcagtcgtc ggcggccggg
    31141 gtgccgaacc agcgggtcag cgcccgcgcc agaccggccg gaccggaacc ggcccaggcc
    31201 acatggccgt cggggcggac cagcagggcc tgcccggccg gcagcgggcc gccggcagcg
    31261 gggcggtcgg cgacgaaggc gacccggtcc gaccaggggg ccgccgtcgc gcgcagcgcc
    31321 ggggcgccgt ccccgtccag ggacagcagc aagccgcgac cggtgcgcaa cagttcggtc
    31381 gtacggcgcc gcgcgccaca ctccgcgggc tccagccacg cgtccggcaa ccgccgtccg
    31441 agcagcgggt gttcgtcgga gtggatctcg gggccgacgc cgacgccctt ggcggcgccg
    31501 gccccgaagt cgtcgccccc gacgcccccg gcgccgtaac cctcgacgcc ctcgacgtcg
    31561 taccggatgc cgaggccgct gatcatcccg gcgaggtgct gccgtacgcc gtccagggcg
    31621 acgagttcgg tgagcagggc gcgggcaggt tcgacctccg ggccgccgag cagcagctcg
    31681 acctgggccc ggatgttggc gaggacctgg cggcccacgg tgtggcgctc ggagtggtag
    31741 gtgtccagga ggtcctcgcc cgcgctgccg cgaacgacgg cggcgagctt ccagccgagg
    31801 ttgaaggcgt cctggacgcc caggttgagg gcctgtccgc cgctcggcat ctgccggtgc
    31861 gccgcgtccc cggcgaacag gacgcgaccg tgccggtagt gggcgagctg ccggttggcg
    31921 tcgccgaagg cgttgaccca caggggggtg ccctggctga tgtcctcgcc ggtgacgcgc
    31981 ttccagacgt cggtgacctc cgcgaagtcc ggttcggcgc ctccgcgttc ggcggcgggg
    32041 cgcccgaact cgtggaccat cacccgggtc accccctcgc gggtggcggc gatggcgagc
    32101 ccgtgctcca ggcgctggaa gcgccggtcg gcgacctcga cgccggagac gtcggcgcgc
    32161 agcagttcgc gtgcggcgtc ccggcccggg aagggggccc ggaccaggcg ccgtacggtg
    32221 ctgtcctcgc cgtcgcagcc gaccaggtag cgggcccgga tgcggacggg accgtaggga
    32281 ccgatggcct cggcctccac cctgtcctgc ccggcgccgg cctgtccggc ctcgtcccgc
    32341 ccggcctcgt cccgcccggc cccctcgctc ttcgcttcca gggacagcag ctggtgccgg
    32401 cgccggagat cggcgcccag cacggcggcc cgccgctgca gcagctcctc ggtgcgggtc
    32461 tgcgcgacct tccactgccc ggggtgcgag ctgggcagcg tcaggtccag cggtacgccg
    32521 ccgaagtgac cgcgcggctc gcacggcggc gtaccgagct cgtccagcag cccgcgggag
    32581 tcgaggatct ccatcgtgcg ggcgtgcagg gtggaggccc gggattcggt ggtcgggccg
    32641 gggcgctggt cgacgacgac cacctcggcg ccgcccagcc tcagctcggt ggcgagcatc
    32701 agcccggcgg ggcccgctcc gaccacgagg acgtcggtgt ccaggatggt cgtgtcggtg
    32761 tcctgatggt ccgtcgtcat cgtcaacgcc tgttctctgc gaaggccttg gcgtgggtga
    32821 gggtggcccg gctgttggtg gacagggccg tgtggacgta ctcgcgcgcg tcggcgacgg
    32881 tggccccgca gccgaggatg ctctcgatgt tgtccgtgtt gagggtgacc gtgtgctggg
    32941 aggtcgccgc gacgccctgg tcggtgtcct cgaaggtcca gtgaccggtg tgcagggtca
    33001 tcagcgcggg gagcgtgacc tgcttgtacg cgatgcgctg gtgcgggaag gtcacccggt
    33061 aggacttggt ggtgtggacg gaaccgtcct tggcccgggt gtccatctcc agggtctgga
    33121 gccccacggt gtcctcttcc agacggaccg tggcgacgtg cggcagacgc tccgaccaca
    33181 ggttcgcctc gttgatgaag gcgtacacgt ccttcgccga accgtcgacg tagacggtgt
    33241 cctcgaagga gaacgtcacc tcctccgccg cgtgcgcgaa ctcgacgttc ttcttcagcg
    33301 cggccagctc ggagcggctg ttcttgtcga cggcctcgtc gatccacagg aggtcgtgcg
    33361 ggtcgtcgtc gacggcgcgg tagtcgtgca gcagccgtac ccgggactcg ttctcgccga
    33421 gcggctcgat gatccaggtg ccgcccatcg cggcgaccgg cggggcggtc acctcctggc
    33481 ggaaggtgat gcgcagggcc tcggggtcca gttcgcggcg cgaggtccag ttcttggcct
    33541 cgccgttggc ggtggcccag atccgtatcc gctcctggga gccgtcgtgc tccacgcggt
    33601 ccacgtggat ggtgggcggg aagatccggg gccagttggt gacctccgcc agcagccggt
    33661 acacggccgg tgcgggcgcg gcgatcgtga tctcgtgctc tacctcacgg gtcgtcatga
    33721 cgctttcttc tccatggctg ggtacgggct gccggtcggt gggggtgctc agaagttgcc
    33781 gagtccgccg cagacgttga tggcctgcgc ggtgaccgag gcggccgtgt cggaggcgag
    33841 gtaggcgacc atgccggcga cctcctcggg ggtggagtag cggccgagcg ggatcttggc
    33901 ctggaacttc tcgaggatgg cgtcctcgga ggtgtcgtag gcggccgcgt atccggcgcg
    33961 cacgcgctgg gccatcggcg tctcgacata gccggggcag acggcgttca cggtgatgcc
    34021 ggtgggggcc agctcattgc cgagggcctt ggtgaaaccg accacgccgt gcttcgaggc
    34081 ggagtagggg gctcccagga ccacgccctg cttgccggcc gtggaggcga tgttgatgac
    34141 gcggccacgg ctcttgtggc gcatgccgcc ggtggtgagc acctcccgcg tcagccggaa
    34201 cacgctgttg aggttggtgt cgatgacatc ggtccacagc tcgtcctcga tgtcggcggt
    34261 gacgccgcca ccggaccggc cggcgttgtt gaccaggacg tcgacggtgc cgaagcggtc
    34321 gaccgcggcc tgcacgaagg cgccgaccga ggcggggtcg cggacgtcga ggaccgtgcc
    34381 gtcggcgtcg atgccctcct cctggaggat cttgacggtc tcggcgacgt tgtccgcgct
    34441 gcgggcgccg atgaacacgc ggtggccggc cgcggccagc gcccgcgcgg acgcgaggcc
    34501 gatgccgctg gtggcccccg atatgagagc gacccgcttt tccagcgttg acatgtgctt
    34561 cctctccctc ttgtgctgcg ggggtgcggc ggtaccggac cggacgaggt caggtgaaag
    34621 gtttcgcccg gtccgggaac gccgtcgggc gtcaggcggc ggcgggctcg tcggcgccga
    34681 actgctggtt cacggcctcg atgagggcgc gcggggtgtc ggcgtcggtc agcaggtcct
    34741 cgtcgaggac gatcccgtac tcgcgctcga tacggctgcc ggtctccagg agcgccagcg
    34801 actcgtagcc gaggacttcg aacggctcgt cgaggatgtc gccgtcgagg tcgacgccct
    34861 cgtcgacacc ggcgccctcc tggaggatgc ggcgcaggtc gtccagggtg aattccgaag
    34921 tggacacgtg ggttccttcc caggtcgaaa tggatcgttc agtcgggggt cttgggggcg
    34981 tcgggggcag ggggtgccgg tcagtcgacg gcgcggacca cgacggccga gttgaagccg
    35041 ccgtaaccgc gggccaggac cagggcggtg cgcacctggg cggtgcgcga ctggttgagg
    35101 accaggtcga ggccgtactc ctcgtcgggg ttgatgtgga ccgtcggagg gatgaggccc
    35161 tcctcgatgg ccagcagcgc ggtggcgacg tcgagcgggg ccgcgccgga gtacagccgg
    35221 cccgtcatcg tcttgggcgc ggtgaccggg acaccccgga ccccgaagac cgccgagatc
    35281 gcgtcggcct cgatacggtc cagctccggc acgcccgccg cgtccgcgaa gaccacgtcg
    35341 acgtcctcgg gcgcggcgcc cgcgtcggcg agggcgagct cgatcgcctt gcgcagggcg
    35401 ggctcgcggt cgctgccggg ccgcgggtcg aacgtcgagc cgtagcccgc gatctcgccg
    35461 tagatcttgg cgccgcgctc gcacgccgac tcggccgact ccatgatcag gatggcgccg
    35521 ccctcgcccg gtacgtaacc ggccgcgtcg gcgtcgaagg gcaggtaggc acgggtcggc
    35581 tcgtcgctgg tgctcagccg gtcgccggcc atctgcgcca cccagcccca gggacagatc
    35641 gacgcgtcga cgcccccgga gacgatcatc ggggtgccct tgcggatgag ccgccggccg
    35701 tgcgccaccg cgtcgagacc gccggcctcg tcactgacga tgacgccgct ggggcccttg
    35761 agcccgttgc ggatggatat ctgaccgctg ttgacggcgt agaaccaggc gaaggactgg
    35821 tacgcggaca cgtactggct gccctggctc cacagcttct ccagctcgcc ctgtccgaac
    35881 tcgaagccgc ccgaggaact ggccgtgacg acgcccatgt cgtactcggg cagttccttg
    35941 gggtcgatgc ccgcgtccgc gagcgcccac tcggcggcga ccagcgccat ccgggtcatg
    36001 tggtcggtct gcggcagcag tcggctcggc agcacatccg cggcgacgaa accgggcacc
    36061 tcgcccgcca gggtcgacgg gtaggaggac gggtcgaagc gggtgacccg cccgatgccg
    36121 ttcttgccgg tccgggtggc ggcccagtag tcctgtgtgc ccagtccgtt gggggcggcg
    36181 atgcccagac cggtcactac caccgtggtg gtcatgccac gctcctctcg ggacgcgcca
    36241 gcaccatggc gctctggaat cccccgaagc cgctgccgac cgtgagcacc gcgtcggtga
    36301 gctgctcacg ggcgaccagc gggacgtagt cgaggtcgca cttggggtct ggggtggtga
    36361 ggttggccgt gggcggcacg acgtggttct ccatcgccag cgcggacgcg gcgatctcga
    36421 tcgagccgat cgcgccgagc gagtgcccga ccatcgactt gatcgagctg accggggtcc
    36481 ggtaggcgtg gtcgcccagg ctccgcttga acgcctcggt ctcgtggcgg tcgttctgct
    36541 tggtgcccga gccgtgcgcg ttgatgtagt cgatctcggt cgcgttcatc ctggcctcgt
    36601 cgagcgcgac cgtgatggcc tcggccatct ccgccccgtc cggacgcaga ccggtcatgt
    36661 ggtacgcgtt cgagcgcgtc gcatagcccg cgatctcggc gtagatgtgc gcgccgcgcc
    36721 gcttggcgct ctccagctcc tccaggacga acacggcggc accctccccg aggacgaacc
    36781 cgttgcgggt cccgtcgaag gggcgcgagg cgcgctcggg tacgtcgtcc cggggcgtcg
    36841 tcgccttgat cgcgtcgaag cacgccatcg tgatcggcga gatcggggcg tcggacgaac
    36901 ccgtgatcat gacgtccgcc gaaccctcac ggagcagctc cacggcgtgc ccgaccgagt
    36961 cgatgccgga cgtacagccc gtggagacca ccgtgttggg gccctgcgcg cccacggccc
    37021 acgcgacctc ggccgcgaag gagctgggga ccaggtagtt gtacaggtgc ggggccgtgt
    37081 aggcgtggtc gaccagatgg agccggccgc cgtcgctgac gacgttgtac tcctcgtcca
    37141 gacccatggt cgcgccgacc gcgctgccga tggtgacgcc gacgcggtac gggtcgtagg
    37201 cgtcgatgtc gataccgctg tcggcgaccg cgccacgggc cgcgaccacc gcgaactggg
    37261 cggcgcggtc catccggcgt atctcctgcg ggcgcagtcc gtgctccgcg ggatcgaagt
    37321 cgatctcggc ggcgacccgg gaacggaacg gactggggtc gaagaacgtg atgcggcggg
    37381 tggccgtacg gccctcgctc agcaggttcc agaagttctt cgccccgaca ccaccggggg
    37441 cgagcacctc gataccggtg atgacaactc gtcggccggt cacgcggacg cctcccagtt
    37501 gtagaagcgt gtggccatcg cgtcggccgg ggagcgccag gtggccgggt cgtacgcctc
    37561 gatgaacggc ttcaggtcct cgctgatctg tatgaagcgg gggtcgtgcc gggcgtgctg
    37621 gatcagctcg ccgccgttgt ccgcgtcgaa gtcctggagg tggaagtaca gaccccggta
    37681 ctggaagagc tggcgccggc gcgtgcccat gcggtgcggc atttccgtgt cgtcgaaatc
    37741 accgaaaatc ttcgcgacgt cgacgctcga cccgggatcc atccgagcca caatcagcgt
    37801 gctgtacata cgtttccctc tcctcggggc ccaccacaca acagttgacg aaagctcata
    37861 ttcagtatct tgggcggtac gtgcggtttc aatattcccc gtgtcaggga attgtcagac
    37921 cggttcagaa ttgcgttgga gaatgccggg aaatgccagg caatgccccg ggaattcagc
    37981 tggtgatttc gcacatggcg gcgcccgagg cgacggacgc gcccacttcg gcggtgaggc
    38041 tcttgacgat ccccgagcgg tgggcgttga ggggctgttc catcttcatg gcctccagga
    38101 cgacgacgag gtcgccctcc ttgacctcct ggccctcctc gaccgcgacc ttgacgatcg
    38161 tgccctgcat gggcgaggcg agcgtgtcac cggaggcgac cgggcccgac ctcctggccg
    38221 cgcggcgctt gggcttggcg ccggcggcga ggccggtgcg ggccagggac atgcccagcg
    38281 aggacggcag cgagacctcg aggcgcttgc cgccgacctc gacgacgacg gactcgcggc
    38341 ccggctcgtc ctccgcctcc gccgcctcgg cggggttggt gaaggccggg atgtcattga
    38401 cgaactcggt ctcgatccag cgggtgtgga ccgtgaacgg gtcggtggag ccggtcagtt
    38461 cgggggcgaa ggccgggtcc ttgacgaccg cgcggtggaa gggcagcgcg gtggccatcc
    38521 cgccgatctc gaactcctcg agggcgcggg cggcgcgctg gagcgcctgc tcccgggtgg
    38581 cgccggtgac gatcagcttc gcgagcaggg agtcccaggc cgggccgatc acactgccgc
    38641 actgcacacc cgcgtccagg cggacgccgg ggccggaggg cggcgcgaag gtggagaccg
    38701 tgccgggggc cgggaggaaa cccctgccgg ggtcttcgcc gttgatgcgg aactcgaagg
    38761 agtggccgcg cagggcgggg tcgccgtagc
//
